Tissue stationary liquid sampling device
By designing a tissue fixation liquid sampling device including a sliding assembly and a sealing cover, the problems of liquid spillage and damage to volatile toxic liquids during fixation liquid sampling in biological research are solved, and a safe and convenient sampling process is achieved.
Patent Information
- Application Number
- CN202421551852.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-03
- Publication Date
- 2025-05-13
- Estimated Expiration
- 2034-07-03
AI Technical Summary
In biological research, the sampling process of tissue fixation fluid is prone to cause liquid leakage, polluting the environment, and volatile toxic liquids may cause teratogenic and carcinogenic, causing damage to the human body.
A tissue fixation fluid sampling device is designed, including a base, through-hole, opening and closing assembly, a housing, a fixing fluid bottle, a slide groove, a U-shaped frame and a sliding assembly. Through the cooperation of the sliding components, the movement and sampling of the fixed liquid bottle are achieved, and through the cooperation of the sealing cap and the water-absorbing plate, liquid spills and damage of volatile toxic liquids are avoided.
It effectively avoids the spillage of fixed liquid and damage of volatile toxic liquids, ensures the safety of R&D personnel, and improves the convenience and practicality of the sampling process.
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Figure CN222866275U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of tissue specimen processing research, and more specifically, particularly relates to a tissue fixative sampling device. Background Art
[0002] In biological research, tissue specimens often need to be fixed to ensure the integrity of the tissue specimens so that researchers can perform subsequent staining, immunohistochemistry and other operations. Generally speaking, tissue specimens are fixed by placing them in a tissue fixative, and a common tissue fixative is formalin fixative. Taking formalin fixative as an example, the formaldehyde in the formalin fixative reacts with the amino groups in the proteins in the tissue specimens to coagulate the proteins, thereby better preserving the antigenicity and fine structure of the tissue. In addition, formalin fixative has strong permeability and good fixation effect, which can meet the requirements of conventional HE, immunohistochemistry, in situ hybridization and other detection work.
[0003] Based on the above, the inventors have discovered the following problems: In current biological research, tissue fluid is usually required for testing. However, when sampling, the liquid is easily spilled outside and is inconvenient to clean, polluting the environment. If it is a volatile toxic liquid, it can cause malformations and carcinogenesis, causing great harm to the human body.
[0004] Therefore, in view of this, the existing structure and defects are studied and improved, and a tissue fixative sampling device is provided to achieve a purpose with greater practical value. Utility Model Content
[0005] In order to solve the above technical problems, the utility model provides a tissue fixative sampling device to solve the problems that the current tissue fixative may leak during sampling and is inconvenient to clean up, and if it is a volatile toxic liquid, it may cause teratogenicity and carcinogenesis, causing great harm to the human body.
[0006] The purpose and effect of the tissue fixative sampling device of the utility model are achieved by the following specific technical means:
[0007] A tissue fixative sampling device comprises a base, a through hole is provided at the bottom of the base, an opening and closing assembly is provided in the through hole, a shell is provided on the top of the base, a fixative bottle is provided in the shell, slide grooves are provided on both sides of the shell, a U-shaped frame is provided on the outside of the slide groove, a sliding assembly is provided in the U-shaped frame, and the sliding assembly is connected to the fixative bottle.
[0008] Furthermore, the sliding assembly includes a groove opened inside the U-shaped frame, a sliding rod is arranged in the groove, the sliding rod is sleeved with a sleeve, a sliding plate is arranged on the top of the sleeve, a sliding block is arranged on the bottom of the sleeve, and the sliding block and the sliding plate are connected to the sliding rod sleeve.
[0009] Furthermore, a mounting ring is provided on the top of the fixing liquid bottle, a connecting block is provided on one side of the mounting ring, and the sliding block passes through the sliding groove and is connected to the connecting block.
[0010] Furthermore, a spring 1 is provided on the top of the sliding rod, one end of the spring 1 is connected to the inner wall of the groove, and the other end of the spring 1 is connected to the sliding plate.
[0011] Furthermore, the opening and closing assembly includes receiving grooves opened on both sides of the through hole, a coil spring is arranged in the receiving groove, one end of the coil spring is connected to a baffle, and a water absorption plate is arranged on the top of the baffle.
[0012] Furthermore, a second spring is provided inside the shell, and a sealing cover is connected to the bottom of the second spring, and the size of the sealing cover matches the fixing liquid bottle.
[0013] Furthermore, a transparent window is provided on one side of the shell, and a scale is provided on one side of the transparent window.
[0014] Compared with the prior art, the utility model has the following beneficial effects:
[0015] 1. Through the cooperation of the U-shaped frame, the slide groove, the groove, the slide rod, the sleeve, the sliding plate, the slider and the connecting block, the sliding plate is pressed to drive the sleeve to move on the slide rod, and then drive the slider to move in the slide groove, and then drive the fixing liquid bottle to move, so that the fixing liquid bottle can be moved to the outside of the shell for sampling. Conversely, when the fixing liquid bottle is stored back into the shell, it is equipped with a sealing cover to avoid the situation where the fixing liquid is a partially volatile toxic liquid, which will cause teratogenicity, carcinogenicity, and damage to the human body, thereby ensuring the safety of R&D personnel.
[0016] 2. Through the cooperation of the storage groove, coil spring, baffle and water absorption plate, when the fixed liquid bottle moves down, the baffle is driven to open, and then the fixed liquid bottle is used for sampling. After sampling, the fixed liquid bottle is stored back into the shell, the baffle rebounds, and the water absorption plate is used to absorb the dripping liquid. The water absorption plate is adhered to the surface of the baffle, which is convenient for subsequent direct replacement and improves convenience. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 The utility model is a stereoscopic schematic diagram of a tissue fixative sampling device.
[0018] Figure 2 The utility model is a schematic diagram of some components of a tissue fixative sampling device.
[0019] Figure 3 The utility model is a cross-sectional schematic diagram of a tissue fixative sampling device.
[0020] Figure 4 The utility model is a tissue fixative sampling device Figure 3 An enlarged schematic diagram of point A in FIG.
[0021] In the figure, the corresponding relationship between the component names and the figure numbers is as follows:
[0022] 1. Base; 2. Through hole; 3. Shell; 4. Fixing liquid bottle; 5. Slide groove; 6. U-shaped frame; 7. Groove; 8. Slide rod; 9. Sleeve; 10. Sliding plate; 11. Sliding block; 12. Mounting ring; 13. Spring 1; 14. Storage groove; 15. Coil spring; 16. Baffle; 17. Water absorption plate; 18. Transparent window; 19. Scale; 20. Connecting block; 21. Spring 2; 22. Sealing cover. DETAILED DESCRIPTION
[0023] The following is a further detailed description of the implementation of the present invention in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but cannot be used to limit the scope of the present invention.
[0024] In the description of the present invention, unless otherwise specified, "multiple" means two or more; the terms "upper", "lower", "left", "right", "inner", "outer", "front end", "rear end", "head", "tail" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", "third" and the like are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.
[0025] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "connected" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0026] Example:
[0027] As attached Figure 1 To Attachment Figure 4 As shown:
[0028] The utility model provides a tissue fixative sampling device, comprising a base 1, a through hole 2 is opened at the bottom of the base 1, an opening and closing component is arranged in the through hole 2, a shell 3 is arranged on the top of the base 1, a fixative bottle 4 is arranged in the shell 3, slide grooves 5 are arranged on both sides of the shell 3, a U-shaped frame 6 is arranged on the outer side of the slide groove 5, a sliding component is arranged in the U-shaped frame 6, and the sliding component is connected to the fixative bottle 4; the base 1 is cylindrical, and its size is larger than that of the shell 3, and it can be placed in a horizontal position when in use, so as to improve the stability of the device and avoid tipping.
[0029] Among them, the sliding assembly includes a groove 7 opened inside the U-shaped frame 6, a sliding rod 8 is arranged in the groove 7, the sliding rod 8 is sleeved with a sleeve 9, a sliding plate 10 is arranged on the top of the sleeve 9, and a slider 11 is arranged at the bottom of the sleeve 9, and the slider 11 and the sliding plate 10 are both sleeved and connected with the sliding rod 8.
[0030] The top of the fixing liquid bottle 4 is provided with a mounting ring 12 , one side of the mounting ring 12 is provided with a connecting block 20 , and the sliding block 11 passes through the sliding groove 5 and is connected with the connecting block 20 .
[0031] Among them, a spring 13 is provided on the top of the sliding rod 8, one end of the spring 13 is connected to the inner wall of the groove 7, and the other end of the spring 13 is connected to the sliding plate 10.
[0032] Among them, the opening and closing component includes a storage groove 14 opened on both sides of the through hole 2, a coil spring 15 is provided in the storage groove 14, one end of the coil spring 15 is connected to a baffle 16, and the top of the baffle 16 is provided with a water absorption plate 17. Through the cooperation of the storage groove 14, the coil spring 15, the baffle 16 and the water absorption plate 17, when the fixed liquid bottle 4 moves down, the baffle 16 is driven to open, and then the fixed liquid bottle 4 is used for sampling. After sampling, the fixed liquid bottle 4 is stored back into the shell 3, the baffle 16 rebounds, and cooperates with the water absorption plate 17 to absorb the dripping liquid, and the water absorption plate 17 is adhered to the surface of the baffle 16, which is convenient for subsequent direct replacement and improves convenience.
[0033] Among them, a spring 21 is provided inside the shell 3, and a sealing cover 22 is connected to the bottom of the spring 21. The size of the sealing cover 22 matches the fixing liquid bottle 4. Through the cooperation of the U-shaped frame 6, the slide groove 5, the groove 7, the slide rod 8, the sleeve 9, the sliding plate 10, the slider 11 and the connecting block 20, the sliding plate 10 is pressed to drive the sleeve 9 to move on the slide rod 8, and then drive the slider 11 to move in the slide groove 5, and then drive the fixing liquid bottle 4 to move, so that the fixing liquid bottle 4 can be moved to the outside of the shell 3 for sampling. On the contrary, when the fixing liquid bottle 4 is stored back into the shell 3, it is matched with the sealing cover 22 to avoid the situation where the fixing liquid is a partially volatile toxic liquid, which will cause teratogenicity and carcinogenicity, and cause harm to the human body, thereby ensuring the safety of R&D personnel.
[0034] A transparent window 18 is disposed on one side of the housing 3 , and a scale 19 is disposed on one side of the transparent window 18 .
[0035] The specific usage and function of this embodiment are as follows:
[0036] First, check the integrity of the device. Then, when sampling is needed, through the cooperation of the U-shaped frame 6, the slide groove 5, the groove 7, the slide rod 8, the sleeve 9, the sliding plate 10, the slider 11 and the connecting block 20, press the sliding plate 10, drive the sleeve 9 to move on the slide rod 8, and then drive the slider 11 to move in the slide groove 5, and then drive the fixing liquid bottle 4 to move, so that the fixing liquid bottle 4 can be moved to the outside of the shell 3 for sampling. On the contrary, when the fixing liquid bottle 4 is stored back into the shell 3, it is matched with the sealing cover 22 to avoid the fixing liquid being a partially volatile toxic liquid, which will cause teratogenicity and carcinogenicity, and cause harm to the human body. Damage occurs to ensure the safety of R&D personnel, and when the fixing liquid bottle 4 moves down, the baffle 16 is driven to open through the cooperation of the storage groove 14, the coil spring 15, the baffle 16 and the water absorption plate 17, and then the fixing liquid bottle 4 is used for sampling. After sampling, the fixing liquid bottle 4 is stored back into the shell 3, the baffle 16 rebounds, and the water absorption plate 17 is matched to absorb the dripping liquid, and the water absorption plate 17 is adhered to the surface of the baffle 16, which is convenient for subsequent direct replacement and improves convenience. When in use, the amount of liquid in the fixing liquid bottle 4 can be observed through the transparent window 18 and then according to the scale 19.
[0037] The embodiments of the present invention are provided for the purpose of illustration and description, and are not intended to be exhaustive or to limit the present invention to the disclosed forms. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiments are selected and described to better illustrate the principles and practical applications of the present invention, and to enable those of ordinary skill in the art to understand the present invention and thereby design various embodiments with various modifications suitable for specific purposes.
Claims
1. A tissue fixative sampling device, comprising a base (1), characterized in that: The bottom of the base (1) is provided with a through hole (2), an opening and closing component is arranged in the through hole (2), the top of the base (1) is provided with a shell (3), a fixing liquid bottle (4) is arranged in the shell (3), sliding grooves (5) are arranged on both sides of the shell (3), a U-shaped frame (6) is arranged on the outside of the sliding groove (5), a sliding component is arranged in the U-shaped frame (6), and the sliding component is connected to the fixing liquid bottle (4).
2. A tissue fixative sampling device as claimed in claim 1, characterized in that: The sliding assembly comprises a groove (7) opened inside the U-shaped frame (6), a sliding rod (8) is arranged in the groove (7), the sliding rod (8) is sleeved with a sleeve (9), a sliding plate (10) is arranged on the top of the sleeve (9), a sliding block (11) is arranged on the bottom of the sleeve (9), and the sliding block (11) and the sliding plate (10) are both sleeved and connected with the sliding rod (8).
3. A tissue fixative sampling device as claimed in claim 2, characterized in that: A mounting ring (12) is provided on the top of the fixing liquid bottle (4), a connecting block (20) is provided on one side of the mounting ring (12), and the sliding block (11) passes through the sliding groove (5) and is connected to the connecting block (20).
4. A tissue fixative sampling device as claimed in claim 3, characterized in that: A spring (13) is provided at the top of the slide rod (8), one end of the spring (13) is connected to the inner wall of the groove (7), and the other end of the spring (13) is connected to the sliding plate (10).
5. A tissue fixative sampling device as claimed in claim 4, characterized in that: The opening and closing assembly comprises a receiving groove (14) provided on both sides of the through hole (2), a coil spring (15) being provided in the receiving groove (14), one end of the coil spring (15) being connected to a baffle (16), and a water absorption plate (17) being provided on the top of the baffle (16).
6. A tissue fixative sampling device as claimed in claim 5, characterized in that: A second spring (21) is arranged inside the housing (3), and a sealing cover (22) is connected to the bottom of the second spring (21), wherein the size of the sealing cover (22) matches that of the fixing liquid bottle (4).
7. A tissue fixative sampling device as claimed in claim 6, characterized in that: A transparent window (18) is provided on one side of the housing (3), and a scale (19) is provided on one side of the transparent window (18).