Inflammation antibody detection kit

Abstract

The utility model discloses an inflammation antibody detection kit, and relates to the technical field of inflammation antibody detection kits, in particular to an inflammation antibody detection kit which comprises a lower layer plate, an upper layer plate and a fixed block, a sample inlet is formed in the top of the fixed block, and rotating columns are fixedly installed on the front face and the rear face of the fixed block. An observation window is formed in the top of the upper-layer plate, a handle is fixedly connected to the side face of the upper-layer plate, an extrusion mechanism is arranged at the top of the upper-layer plate, a flow dividing groove is formed in the bottom end of the sample inlet, a through hole is formed in the fixing block, a containing groove is formed in the top of the lower-layer plate, and a supporting plate is fixedly installed at the inner bottom of the containing groove; a nitrocellulose membrane is arranged at the top of the supporting plate, a sample pad and a water absorption pad are arranged at the top of the nitrocellulose membrane, a clamping column is fixedly connected to the bottom of the upper-layer plate, a clamping groove is formed in the top of the lower-layer plate, a sample can be rapidly spread out for a contact reaction due to the arrangement of the extrusion mechanism, and internal parts can be conveniently replaced due to the arrangement of the rotating mechanism.

Description

Technical Field

[0001] The utility model relates to the technical field of inflammatory antibody detection kits, in particular to an inflammatory antibody detection kit. Background Art

[0002] At present, there are many markers selected for detecting inflammation, including CRP, PCT, SAA, IL-6 and HBP, etc. In the prior art, when the above markers are rapidly detected, some indicators can be detected by integrated test strips, while others need to be detected by separate test strips. Therefore, when testing, it is necessary to collect and prepare samples, and then add the samples to the injection holes of each test strip one by one for testing. This test method does not detect each inflammatory indicator at the same time. First, it is too cumbersome, and second, there will be differences in test time when testing samples, which affects the accuracy of the test.

[0003] An inflammatory antibody detection kit disclosed in the Chinese utility model patent application disclosure CN218298270U has the advantages of extending the contact time and thus enhancing the detection sensitivity, but the inflammatory antibody detection kit still has disadvantages: First, when the sample is injected into the kit, the inflammatory antibody detection kit naturally flows to the detection pad for binding reaction. During actual use, the natural contact reaction rate may be slow, resulting in low detection efficiency; Second, after the inflammatory antibody detection kit is used for a long time, the effect of the nitrocellulose membrane used for detection reaction inside will decrease. If it is not replaced in time, the detection result may be biased. Utility Model Content

[0004] 1. Technical issues to be resolved

[0005] In view of the deficiencies of the prior art, the utility model provides an inflammatory antibody detection kit, which solves the problems raised in the above-mentioned background technology.

[0006] (II) Technical solution

[0007] To achieve the above objectives, the utility model is implemented through the following technical solutions: an inflammatory antibody detection kit, comprising a lower plate, an upper plate and a fixed block, the top of the fixed block is provided with an injection port, the front and rear surfaces of the fixed block are fixedly installed with rotating columns, the top of the upper plate is provided with an observation window, the side of the upper plate is fixedly connected with a handle, the top of the upper plate is provided with an extrusion mechanism, the bottom end of the injection port is provided with a diversion groove, the interior of the fixed block is provided with a through hole, the top of the lower plate is provided with a placement groove, the inner bottom of the placement groove is fixedly installed with a support plate, the top of the support plate is provided with a nitrocellulose membrane, the top of the nitrocellulose membrane is provided with a sample pad and a water absorbent pad, the bottom of the upper plate is fixedly connected with a card column, and the top of the lower plate is provided with a card groove.

[0008] Optionally, the lower plate and the upper plate have the same size, the lower plate and the upper plate are symmetrically arranged on the left and right sides, and the fixing block is located at the center between the left and right lower plates and the upper plate.

[0009] Optionally, the end of the upper plate is rotatably connected to a rotating column, the observation window is supported by a transparent material, and the handle is fixedly mounted on the side of the upper plate opposite to the rotating end.

[0010] Optionally, the extrusion mechanism includes an extrusion rod, a pressing handle and an extrusion plate, wherein the extrusion rod is slidably connected to the top of the upper plate, the pressing handle is fixedly installed on the top of the extrusion rod, and the extrusion plate is fixedly connected to the bottom end of the extrusion rod.

[0011] Optionally, a storage groove is provided at the bottom of the upper plate, the pressing handle is located above the top of the upper plate, the size of the extrusion plate is matched with the size of the storage groove, and the extrusion plate is located inside the storage groove.

[0012] Optionally, the diverter trough is connected with the injection port, the top of the through hole is connected with the bottom of the diverter trough, the bottom of the through hole passes through the interior of the placement groove, the absorbent pad and the sample pad are respectively located on the left and right sides of the top of the nitrocellulose membrane, the nitrocellulose membrane is provided with a target detection line and a quality control line, and the card column is clamped in the interior of the card slot.

[0013] The utility model provides an inflammatory antibody detection kit, which has the following beneficial effects:

[0014] 1. The inflammatory antibody detection kit has the effect of sample test by setting the sample pad. By the coordinated setting of the squeezing rod and the squeezing plate, the squeezing rod and the squeezing plate can be pressed downward by the pressing handle during use so that the sample can quickly fill the entire placement groove, thereby improving the sample binding reaction speed and achieving the purpose of improving work efficiency.

[0015] 2. The inflammatory antibody detection kit has a handle setting so that the upper plate can be easily opened. The upper plate can be easily turned upward and opened during use by coordinating the rotating column and the clamping column, thereby facilitating the replacement of the internal plain film and achieving the purpose of improving the quality of use. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0017] Figure 2 This is a schematic diagram of the main structure of the utility model;

[0018] Figure 3 This is a schematic diagram of the top view structure of the utility model;

[0019] Figure 4 It is a schematic diagram of the main cross-sectional structure of the utility model.

[0020] In the figure: 1. lower plate; 2. upper plate; 3. fixing block; 4. injection port; 5. rotating column; 6. observation window; 7. handle; 8. squeezing rod; 9. pressing handle; 10. storage slot; 11. squeezing plate; 12. diversion slot; 13. through hole; 14. placement slot; 15. support plate; 16. nitrocellulose membrane; 17. sample pad; 18. absorbent pad; 19. card column; 20. card slot. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0022] Embodiment 1:

[0023] See also Figures 1 to 4The utility model provides a technical solution: an inflammatory antibody detection kit, comprising a lower plate 1, an upper plate 2 and a fixed block 3. The lower plate 1 has the same size as the upper plate 2. The lower plate 1 and the upper plate 2 are both symmetrically arranged on the left and right. The fixed block 3 is located at the center between the left and right lower plates 1 and the upper plate 2. An injection port 4 is provided on the top of the fixed block 3. Rotating columns 5 are fixedly installed on the front and rear surfaces of the fixed block 3. The end of the upper plate 2 is rotatably connected to the rotating column 5. The observation window 6 is supported by a transparent material. The handle 7 is fixedly installed on the side of the upper plate 2 opposite to the rotating end. The setting of the observation window 6 is convenient for observing the reaction of the internal sample. An observation window 6 is provided on the top of the upper plate 2. A shunt slot 12 is provided at the bottom end of the injection port 4. A through hole 13 is provided inside the fixed block 3. A placement groove 14 is provided on the top of 1, a support plate 15 is fixedly installed on the inner bottom of the placement groove 14, a nitrocellulose membrane 16 is provided on the top of the support plate 15, a sample pad 17 and a water absorbent pad 18 are provided on the top of the nitrocellulose membrane 16, a card column 19 is fixedly connected to the bottom of the upper plate 2, a card slot 20 is provided on the top of the lower plate 1, the shunt groove 12 is connected with the injection port 4, the top of the through hole 13 is connected with the bottom of the shunt groove 12, the bottom of the through hole 13 passes through the inside of the placement groove 14, the water absorbent pad 18 and the sample pad 17 are respectively located on the left and right sides of the top of the nitrocellulose membrane 16, the nitrocellulose membrane 16 is provided with a target detection line and a quality control line, the card column 19 is connected to the inside of the card slot 20, and the arrangement of the card column 19 and the card slot 20 facilitates the connection between the upper plate 2 and the lower plate 1.

[0024] When using the inflammatory antibody detection kit, the antibody sample is first injected into the interior of the injection port 4, diverted through the diversion groove 12, and then injected into the interior of the placement groove 14 through the through holes 13 on both sides. First, a preliminary sample reaction is carried out through the sample pad 17, and then the sample is quickly distributed to the surface of the nitrocellulose membrane 16 through the extrusion mechanism so that it can fully contact and react. Then, during the contact reaction, the excess water will be absorbed by the absorbent pad 18 to avoid affecting the result of the sample reaction detection. At this time, the internal reaction result can be observed and judged through the observation window 6. After long-term use, the upper plate 2 can be rotated upward through the rotating column 5 through the handle 7 to make the card column 19 detach from the interior of the card slot 20. Then the nitrocellulose membrane 16, the sample pad 17 and the absorbent pad 18 in the placement groove 14 can be replaced and the interior can be cleaned. It is very convenient to use and easy to operate.

[0025] Embodiment 2:

[0026] See also Figures 1 to 4The utility model provides a technical solution: an inflammatory antibody detection kit, a handle 7 is fixedly connected to the side of the upper plate 2, and a squeezing mechanism is arranged on the top of the upper plate 2, the squeezing mechanism includes a squeezing rod 8, a pressing handle 9 and a squeezing plate 11, the squeezing rod 8 is slidably connected to the top of the upper plate 2, the pressing handle 9 is fixedly installed on the top of the squeezing rod 8, the squeezing plate 11 is fixedly connected to the bottom end of the squeezing rod 8, a storage groove 10 is opened at the bottom of the upper plate 2, the pressing handle 9 is located above the top of the upper plate 2, the size of the squeezing plate 11 is adapted to the size of the storage groove 10, the squeezing plate 11 is located inside the storage groove 10, and the arrangement of the squeezing mechanism can facilitate the internal sample to be quickly spread out for binding reaction.

[0027] When using the inflammatory antibody detection kit, when the sample enters the placement groove 14, the pressing handle 9 can be pressed downward to push the squeezing rod 8 to drive the squeezing plate 11 to move downward, so that the squeezing plate 11 is separated from the interior of the storage groove 10, and the sample is squeezed to quickly fill the interior of the placement groove 14, so that it can fully contact and react with the nitrocellulose membrane 16. It is very convenient to use and highly practical.

[0028] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. An inflammatory antibody detection kit, comprising a lower plate (1), an upper plate (2) and a fixing block (3), characterized in that: The fixed block (3) has an injection port (4) at the top, and rotating columns (5) are fixedly mounted on the front and rear surfaces of the fixed block (3). The top of the upper plate (2) has an observation window (6), and a handle (7) is fixedly connected to the side of the upper plate (2). The top of the upper plate (2) has an extrusion mechanism. The bottom of the injection port (4) has a diversion slot (12). The fixed block (3) has a through hole (13) inside. The top of the lower plate (1) has a placement slot (14), and a support plate (15) is fixedly mounted on the inner bottom of the placement slot (14). The top of the support plate (15) has a nitrocellulose membrane (16), and the top of the nitrocellulose membrane (16) has a sample pad (17) and a water absorbent pad (18). The bottom of the upper plate (2) has a fixedly connected clamping column (19), and the top of the lower plate (1) has a clamping slot (20).

2. An inflammatory antibody detection kit according to claim 1, characterized in that: The lower plate (1) and the upper plate (2) have the same size, and the lower plate (1) and the upper plate (2) are both symmetrically arranged on the left and right sides, and the fixing block (3) is located at the center between the left and right lower plates (1) and the upper plate (2).

3. An inflammatory antibody detection kit according to claim 1, characterized in that: The end of the upper plate (2) is rotatably connected to the rotating column (5), the observation window (6) is supported by a transparent material, and the handle (7) is fixedly mounted on the side of the upper plate (2) opposite to the rotating end.

4. An inflammatory antibody detection kit according to claim 1, characterized in that: The extrusion mechanism comprises an extrusion rod (8), a pressing handle (9) and an extrusion plate (11); the extrusion rod (8) is slidably connected to the top of the upper plate (2); the pressing handle (9) is fixedly mounted on the top of the extrusion rod (8); and the extrusion plate (11) is fixedly connected to the bottom end of the extrusion rod (8).

5. An inflammatory antibody detection kit according to claim 4, characterized in that: A storage groove (10) is provided at the bottom of the upper plate (2), the pressing handle (9) is located above the top of the upper plate (2), the size of the extrusion plate (11) is matched with the size of the storage groove (10), and the extrusion plate (11) is located inside the storage groove (10).

6. An inflammatory antibody detection kit according to claim 1, characterized in that: The shunt groove (12) is connected to the injection port (4), the top of the through hole (13) is connected to the bottom of the shunt groove (12), the bottom of the through hole (13) penetrates into the interior of the placement groove (14), the absorbent pad (18) and the sample pad (17) are respectively located on the left and right sides of the top of the nitrocellulose membrane (16), the nitrocellulose membrane (16) is provided with a target detection line and a quality control line, and the card column (19) is connected to the interior of the card slot (20).

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