Transcranial magnetic stimulator and system for generating repeated pairwise stimulation

Abstract

The utility model discloses a transcranial magnetic stimulator and system for generating repeated pairwise stimulation, the transcranial magnetic stimulator adopts a main control module, a stimulation module and a coil module which are electrically connected in sequence, and a plurality of replacement modules are respectively connected with the single coil module. Or the plurality of replacement modules are respectively connected with the plurality of coil modules in a one-to-one correspondence manner, a stimulation instruction is issued to the plurality of control units in the stimulation module through the main control module, and the stimulation instruction comprises a started lock time interval, so that the plurality of stimulation units start stimulation at a certain time interval, and multi-beat paired stimulation or single-beat paired stimulation is realized. The transcranial magnetic stimulator for generating repeated paired stimulation is simple in technology, convenient to operate, low in cost and easy to widely popularize.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, and in particular to a transcranial magnetic stimulator and a system for generating repeated paired stimulation. Background Art

[0002] Transcranial magnetic stimulation (TMS) is a painless, non-invasive physical neuromodulation technology. Its main technical principle is to use the Faraday electromagnetic induction principle to apply a transient pulsed magnetic field to the cerebral cortex, causing the cortical neurons to depolarize and generate action potentials, thereby affecting the electrical activity of the cerebral cortex and achieving the effect of neuromodulation. Its non-invasive, painless physical characteristics and deep stimulation have been increasingly used in clinical and scientific research.

[0003] At present, most magnetic stimulators on the market only support single pulse, repetitive pulse, and burst pulse output modes. The few transcranial magnetic stimulators that can support paired stimulation modes and are specifically used to produce repetitive paired stimulation are also customized products for scientific research purposes launched by individual manufacturers. They are expensive and cannot support multiple stimulation modes, making them difficult to be widely promoted in clinical applications. Utility Model Content

[0004] The utility model aims to solve the technical problems existing in the background technology and propose a transcranial magnetic stimulator for generating repeated paired stimulation.

[0005] In order to achieve the above technical objectives, the technical solution adopted by the utility model in the first aspect is as follows:

[0006] A transcranial magnetic stimulator for generating repeated paired stimulation, comprising a main control module, a stimulation module and a plurality of coil modules electrically connected in sequence;

[0007] The stimulation module includes a plurality of control units and a plurality of replacement modules, wherein the plurality of control units are electrically connected to the plurality of replacement modules one by one, the control unit is electrically connected to the main control module, the plurality of replacement modules are connected to a single coil module, or the plurality of replacement modules are connected to the plurality of coil modules one by one;

[0008] The replacement module includes a stimulation unit, which is electrically connected to the coil module for activating magnetic stimulation of the coil module;

[0009] The main control module sends stimulation instructions to multiple control units to drive multiple stimulation units to start stimulation at certain time intervals.

[0010] Preferably, the replacement module further includes a heat dissipation unit, which is connected to the coil module for dissipating heat from the coil module.

[0011] Preferably, the heat dissipation unit includes a liquid cooling cycle heat dissipation component.

[0012] Preferably, the coil module is provided with an electrical interface and a heat dissipation pipe, the coil module is electrically connected to the stimulation unit via the electrical interface, and the coil module is connected to the liquid cooling circulation heat dissipation component via the heat dissipation pipe.

[0013] Preferably, the stimulation module further comprises a power supply unit and a control switch electrically connected to the power supply unit, the power supply unit is electrically connected to the control unit and the plurality of replacement modules respectively, and the control switch is used to turn on or off the power supply unit.

[0014] Preferably, the stimulation unit comprises a front-stage circuit, a boost circuit, a pulse capacitor and a thyristor, two ends of the boost circuit are electrically connected to the front-stage circuit and the pulse capacitor respectively, the control unit is electrically connected to the boost circuit and the thyristor respectively, the first end of the coil module is electrically connected to the positive end of the pulse capacitor through the thyristor, and the second end of the coil module is electrically connected to the negative end of the pulse capacitor;

[0015] Among them, under the instruction of the control unit to transmit the control voltage signal, the current in the previous circuit is sent to the pulse capacitor through the boost circuit. Under the instruction of the control unit to transmit the trigger control signal, the thyristor is opened, and the current flows from the positive end of the pulse capacitor through the thyristor and the coil module to resonate until the negative pressure is reached. The current flows back to the negative end of the pulse capacitor, causing the coil module to generate a transient magnetic field to achieve magnetic stimulation.

[0016] The utility model provides a system in a second aspect, characterized by comprising a transcranial magnetic stimulator for generating repeated paired stimulation as in any one of the above solutions.

[0017] Compared with the prior art, the utility model has the following beneficial technical effects: a main control module, a stimulation module and a coil module are electrically connected in sequence, a plurality of replacement modules are respectively connected to a single coil module, or a plurality of replacement modules are respectively connected to a plurality of coil modules in a one-to-one correspondence, and a stimulation instruction is issued to a plurality of control units in the stimulation module through the main control module, wherein the stimulation instruction includes a start-up lock interval, so that a plurality of stimulation units start stimulation at a certain time interval, so as to realize multi-beat paired stimulation or single-beat paired stimulation, and the transcranial magnetic stimulator for generating repeated paired stimulation is simple in technology, easy to operate, low in cost, and easy to be widely promoted. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 The structure of the embodiment of the utility model is shown in FIG. Figure 1 ;

[0019] Figure 2 The structure of the embodiment of the utility model is shown in FIG. Figure 2 ;

[0020] Figure 3 The structure of another embodiment of the utility model is shown in FIG. Figure 2 ;

[0021] Figure 4 The structure of the embodiment of the utility model is shown in FIG. Figure 3 ;

[0022] Figure 5 It is an equivalent single-path schematic diagram of the stimulation unit and the coil module in the embodiment of the utility model.

[0023] Figure numbers: 100 main control module, 200 stimulation module, 201 control unit, 202 replacement module, 2021 stimulation unit, 2021a pre-stage circuit, 2021b boost circuit, 2021c pulse capacitor, 2021d thyristor, 2022 heat dissipation unit, 203 power supply unit, 204 control switch, 300 coil module, 301 electrical interface, 302 heat dissipation pipe. DETAILED DESCRIPTION

[0024] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features in the embodiments can be combined with each other.

[0025] In the description of the present utility model, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or component referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present utility model. In addition, the terms "first", "second", etc. are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, features defined as "first", "second", etc. may explicitly or implicitly include one or more features. In the description of the present utility model, unless otherwise specified, "multiple" means two or more.

[0026] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or a specific connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood by specific circumstances.

[0027] The specific embodiments of the present utility model are described in detail below with reference to the accompanying drawings.

[0028] like Figure 1-Figure 5 As shown, the utility model proposes a transcranial magnetic stimulator for generating repeated paired stimulation in the first aspect, which includes a main control module 100, a stimulation module 200 and a plurality of coil modules 300 electrically connected in sequence, the stimulation module 200 includes a plurality of control units 201 and a plurality of replacement modules 202, the plurality of control units 201 are electrically connected to the plurality of replacement modules 202 in a one-to-one correspondence, the control unit 201 is electrically connected to the main control module 100, the plurality of replacement modules 202 are respectively connected to a single coil module 300, or the plurality of replacement modules 202 are respectively connected to the plurality of coil modules 300 in a one-to-one correspondence, the replacement module 202 includes a stimulation unit 2021, the stimulation unit 2021 is electrically connected to the coil module 300 for activating the magnetic stimulation of the coil module 300, wherein the main control module 100 sends a stimulation instruction to the plurality of control units 201 to drive the plurality of stimulation units 2021 to start stimulation at a certain time interval.

[0029] The specific implementation is as follows: In this embodiment, two embodiments are included, one of which is that multiple replacement modules 202 are respectively connected to a single coil module 300, and a stimulation instruction is issued to multiple control units 201 in the stimulation module 200 through the main control module 100, wherein the stimulation instruction includes a start lock interval, so that multiple stimulation units 2021 start stimulation at a certain time interval, such as one stimulation unit 2021 first outputs a stimulation, and then the next stimulation unit 2021 outputs a second stimulation at a very small time interval, and so on, to complete a single-beat paired stimulation, wherein the time interval is 1-10m s, specifically, it is to be greater than the time consumed by the stimulation process itself. Secondly, multiple replacement modules 202 are respectively connected to multiple coil modules 300 in a one-to-one correspondence, and one stimulation unit 2021 corresponds to one coil module 300. For example, one stimulation unit 2021 first outputs a stimulation to its corresponding coil module 300, and then the next stimulation unit 2021 outputs a second stimulation to its corresponding coil module 300 at a very small time interval, and so on, to complete multi-beat paired stimulation, and the time interval is also 1-10ms, so as to realize that the transcranial magnetic stimulator for generating repeated paired stimulation supports multiple stimulation modes.

[0030] Furthermore, the replacement module 202 also includes a heat dissipation unit 2022, which is connected to the coil module 300 for dissipating heat from the coil module 300, and the heat dissipation unit 2022 includes a liquid cooling circulation heat dissipation component.

[0031] The coil module 300 is provided with an electrical interface 301 and a heat dissipation pipe 302 . The coil module 300 is electrically connected to the stimulation unit 2021 via the electrical interface 301 , and the coil module 300 is connected to the liquid cooling circulation heat dissipation component via the heat dissipation pipe 302 .

[0032] Specifically, the replacement module 202 is an integrated module packaged by a stimulation unit 2021 and a heat dissipation unit 2022, wherein in actual products, the stimulation unit 2021 and the heat dissipation unit 2022 are both rectangular structures of the same size, and the first ends of both are provided with an interface electrically connected to the control unit 201, the second end of the stimulation unit 2021 is electrically connected to the electrical interface 301 of the coil module 300, and the second end of the heat unit 2022 is connected to the heat dissipation pipe 302 of the coil module 300, wherein, in this embodiment, the heat dissipation unit 2022 adopts a liquid-cooled liquid-cooled circulating heat dissipation component, which is composed of a shell, inlet and outlet water valves, a water tank, a heat exchanger, a compressor, a heat dissipation block, a fan and a power supply, wherein the heat dissipation pipe 302 is a double-nozzle structure, which is respectively connected to the inlet and outlet water valves, so that the heat dissipation liquid can circulate between the liquid-cooled circulating heat dissipation component and the coil module 300, thereby achieving a heat dissipation effect.

[0033] Furthermore, the stimulation module 200 also includes a power supply unit 203 and a control switch 204 electrically connected to the power supply unit 203 . The power supply unit 203 is electrically connected to the control unit 201 and the plurality of replacement modules 202 , respectively. The control switch 204 is used to turn on or off the power supply unit 203 .

[0034] The stimulation unit 2021 includes a front-stage circuit 2021a, a boost circuit 2021b, a pulse capacitor 2021c and a thyristor 2021d, two ends of the boost circuit 2021b are electrically connected to the front-stage circuit 2021a and the pulse capacitor 2021c, respectively, the control unit 201 is electrically connected to the boost circuit 2021b and the thyristor 2021d, the first end of the coil module 300 is electrically connected to the positive end of the pulse capacitor 2021c through the thyristor 2021d, and the second end of the coil module 300 is electrically connected to the negative end of the pulse capacitor 2021c;

[0035] Among them, under the instruction of the control unit 201 to transmit the control voltage signal, the current in the front-stage circuit 2021a is sent to the pulse capacitor 2021c through the boost circuit 2021b, and under the instruction of the control unit 201 to transmit the trigger control signal, the thyristor 2021d is opened, and the current flows from the positive end of the pulse capacitor 2021c through the thyristor 2021d and the coil module 300 to resonate until the negative pressure is reached, and the current flows back to the negative end of the pulse capacitor 2021c, so that the coil module 300 generates a transient magnetic field to achieve magnetic stimulation.

[0036] The utility model provides a system in a second aspect, characterized by comprising a transcranial magnetic stimulator for generating repeated paired stimulation as in any one of the above solutions.

[0037] The above are one or more implementation methods provided in combination with specific content, and it is not intended that the specific implementation of the utility model is limited to these descriptions. Any method, structure, etc. similar to or identical to the method, structure, etc. of the utility model, or any technical deduction or replacement based on the concept of the utility model, shall be deemed to be within the protection scope of the utility model.

Claims

1. A transcranial magnetic stimulator for producing repeated paired stimulation, characterized in that: It comprises a main control module (100), a stimulation module (200) and a plurality of coil modules (300) which are electrically connected in sequence; The stimulation module (200) comprises a plurality of control units (201) and a plurality of replacement modules (202), wherein the plurality of control units (201) are electrically connected to the plurality of replacement modules (202) in a one-to-one correspondence, the plurality of control units (201) are electrically connected to the main control module (100), the plurality of replacement modules (202) are connected to a single coil module (300), or the plurality of replacement modules (202) are connected to the plurality of coil modules (300) in a one-to-one correspondence; The replacement module (202) comprises a stimulation unit (2021), wherein the stimulation unit (2021) is electrically connected to the coil module (300) to activate magnetic stimulation of the coil module (300); The main control module (100) sends stimulation instructions to the plurality of control units (201) to drive the plurality of stimulation units (2021) to start stimulation at certain time intervals.

2. A transcranial magnetic stimulator for generating repeated paired stimulation according to claim 1, characterized in that: The replacement module (202) further comprises a heat dissipation unit (2022), wherein the heat dissipation unit (2022) is connected to the coil module (300) to dissipate heat from the coil module (300).

3. A transcranial magnetic stimulator for generating repeated paired stimulation according to claim 2, characterized in that: The heat dissipation unit (2022) includes a liquid cooling circulation heat dissipation component.

4. A transcranial magnetic stimulator for generating repeated paired stimulation according to claim 3, characterized in that: The coil module (300) is provided with an electrical interface (301) and a heat dissipation pipe (302); the coil module (300) is electrically connected to the stimulation unit (2021) via the electrical interface (301); and the coil module (300) is connected to the liquid-cooling circulation heat dissipation component via the heat dissipation pipe (302).

5. A transcranial magnetic stimulator for generating repeated paired stimulation according to claim 1, characterized in that: The stimulation module (200) further comprises a power supply unit (203) and a control switch (204) electrically connected to the power supply unit (203); the power supply unit (203) is electrically connected to the control unit (201) and the plurality of replacement modules (202), respectively; the control switch (204) is used to turn on or off the power supply unit (203).

6. A transcranial magnetic stimulator for generating repeated paired stimulation according to claim 1, characterized in that: The stimulation unit (2021) comprises a front-stage circuit (2021a), a boost circuit (2021b), a pulse capacitor (2021c) and a thyristor (2021d); two ends of the boost circuit (2021b) are electrically connected to the front-stage circuit (2021a) and the pulse capacitor (2021c), respectively; the control unit (201) is electrically connected to the boost circuit (2021b) and the thyristor (2021d), respectively; a first end of the coil module (300) is electrically connected to the positive end of the pulse capacitor (2021c) through the thyristor (2021d); and a second end of the coil module (300) is electrically connected to the negative end of the pulse capacitor (2021c); Wherein, under the instruction of the control unit (201) to transmit a control voltage signal, the current in the front-stage circuit (2021a) is sent to the pulse capacitor (2021c) through the boost circuit (2021b), and under the instruction of the control unit (201) to transmit a trigger control signal, the thyristor (2021d) is opened, and the current flows from the positive end of the pulse capacitor (2021c) through the thyristor (2021d) and the coil module (300) to resonate until negative pressure is reached, and the current flows back to the negative end of the pulse capacitor (2021c), so that the coil module (300) generates a transient magnetic field to achieve magnetic stimulation.

7. A system, characterized in that: It comprises a transcranial magnetic stimulator for generating repeated paired stimulation as described in any one of claims 1 to 6 above.

Images