Consumable for automatic preparation of PRP centrifugal extraction

Abstract

The consumable comprises an outer pipe body, a top cover, a base and a built-in central liquid taking pipe, the top cover is provided with an injection port, a suction port and a ventilation port, the upper end of the central liquid taking pipe is communicated with the suction port, the lower end of the central liquid taking pipe forms a liquid taking port in the outer pipe body, a sealed piston is arranged in the lower end of the outer pipe body, and a liquid taking port is formed in the upper end of the central liquid taking pipe. The base is provided with an operation opening, the piston is connected with an installation base, the installation base is exposed out of the operation opening, and the exposed end of the installation base is provided with a pushing taper hole. According to the utility model, the position of the boundary liquid level of red blood cells and PRP is changed by utilizing the axial movement of the piston, so that the structure of the consumable is simplified and the manufacturing cost is reduced; on the basis, the boundary liquid level can be automatically adjusted through the linear motor and the push rod mechanism, complex positioning and clamping structures do not need to be arranged, the structure of the liquid level adjusting device is greatly simplified, the cost of automatic equipment is reduced, and the adjusting precision of the boundary liquid level can be guaranteed.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, and particularly relates to a consumable for automatic preparation of PRP centrifugal extraction. Background Art

[0002] Platelet-rich plasma (PRP) is rich in various bioactive substances such as growth factors, cytokines and antimicrobial peptides, and has the functions of promoting cell proliferation, differentiation, matrix synthesis, tissue regeneration and repair, etc., playing an important role in regenerative medicine.

[0003] The Chinese patents CN216678283U (November 26, 2021) and CN 116273502A (March 31, 2023) previously applied for by the applicant respectively disclose a consumable for PRP preparation with an internal central liquid extraction tube and an automatic PRP centrifugal extraction integrated device. The former extracts PRP through the liquid extraction port at the lower end of the central liquid extraction tube, and completes the PRP preparation process in a set of consumables; the latter cooperates with the former to achieve a high degree of automation of PRP centrifugation and suction.

[0004] For the above-mentioned consumable for PRP preparation, the interface between red blood cells and PRP is adjusted by rotating the bottom cover; correspondingly, the automatic device is provided with an interface adjustment component, and through a visual recognition device, an adjustment motor and a rotating head are used to control the bottom cover to rotate to a predetermined position. It is found in research and trial that the rotating head and the bottom cover need to be accurately aligned, requiring circumferential fixation and axial sliding, which is difficult to achieve and results in a high equipment cost. In addition, the rotating bottom cover of the above-mentioned consumable for PRP preparation adopts a double-sealing method between the inner and outer walls of the outer tube body, and its sealing structure is complex and the manufacturing difficulty is high, and there is still a risk of leakage under high-speed centrifugation. Summary of the Utility Model

[0005] In order to more conveniently realize the automatic adjustment of the interface between red blood cells and PRP in the consumable, the utility model provides a consumable for automatic preparation of PRP centrifugal extraction.

[0006] The technical solution adopted by the utility model is as follows: A consumable for automatic preparation of PRP centrifugal extraction, including an outer tube body, a top cover, a base and an internally placed central liquid extraction tube. The top cover is provided with an injection port, a suction port and a ventilation port. The upper end of the central liquid extraction tube is communicated with the suction port, and the lower end forms a liquid extraction port in the outer tube body. It is characterized in that a sealed piston is arranged inside the lower end of the outer tube body, and an operation port is arranged on the base.

[0007] Preferably, it further includes a mounting base and an adjusting base. The mounting base and the piston are assembled into an integral structure. The mounting base is exposed from the operation port. One end of the exposed mounting base is provided with a pushing tapered hole. The adjusting base is detachably connected to the mounting base.

[0008] Preferably, the adjusting base and the mounting base are connected by a threaded connection or a rotary snap connection.

[0009] Preferably, the piston is made of an elastic material. An inner clamping groove is provided in the insertion hole at the lower end of the piston. The mounting base has an outer clamping groove. The piston is inserted and clamped with the mounting base.

[0010] Preferably, the main body part of the outer tube body, the cross sections of the top cover, the base and the adjusting base are polygons with the same shape.

[0011] Preferably, the ventilation port is provided with mesh grid holes.

[0012] Preferably, pressing plate grooves are provided at the positions corresponding to the injection port, the suction port and the ventilation port on the top cover. Pressing plates are assembled in the pressing plate grooves. The pressing plates are respectively provided with a first through hole, a second through hole and the mesh grid holes corresponding to the injection port, the suction port and the ventilation port.

[0013] Preferably, a positioning part is provided on the surface of the pressing plate facing the top cover, and a positioning port is correspondingly provided on the top cover.

[0014] Preferably, a first seal is provided between the outer peripheral wall of the piston and the inner peripheral wall of the outer tube body, and a second seal is provided between the lower surface of the piston and the upper surface of the base.

[0015] Preferably, at least two seal ring grooves for accommodating sealing rings are provided on the outer peripheral wall of the piston. The sealing rings form the first seal; a V-shaped sealing protrusion is provided at the bottom of the piston, and a V-shaped sealing groove opening is correspondingly provided on the base. The V-shaped sealing protrusion and the V-shaped sealing groove opening form the second seal.

[0016] The utility model has the following beneficial effects: The utility model uses the axial movement of the piston to change the position of the demarcation liquid surface between red blood cells and PRP, simplifies the structure and manufacturing cost of the consumable itself; on this basis, the automatic adjustment of the demarcation liquid surface can be realized by a linear motor and a push rod mechanism, without setting complex positioning and clamping structures, greatly simplifies the structure of the liquid surface adjustment device, reduces the cost of automatic equipment, and can ensure the accuracy of the demarcation liquid surface adjustment. Description of the Drawings

[0017] Figure 1 It is a schematic diagram of an embodiment of the utility model.

[0018] Figure 2It is an assembly schematic diagram of an embodiment of the present utility model (the sealing ring is not shown).

[0019] Figure 3 It is an assembly schematic diagram of the top cover and the pressing plate in an embodiment of the present utility model.

[0020] Figure 4 It is an assembly schematic diagram of the piston, the mounting seat and the adjusting seat in an embodiment of the present utility model.

[0021] Figure 5 It is an assembly schematic diagram of the piston, the mounting seat and the adjusting seat in another embodiment of the present utility model.

[0022] Outer tube body 1; top cover 2, injection port 201, suction port 202, ventilation port 203, pressing plate groove 204, positioning port 205; base 3, operation port 301, V-shaped sealing groove port 302; central liquid extraction tube 4, liquid extraction port 401; piston 5, insertion hole 501, inner card slot 502, sealing ring groove 503, V-shaped sealing protrusion 504; mounting seat 6, top push tapered hole 601, outer card slot 602; adjusting seat 7; pressing plate 8, first through hole 801, second through hole 802, mesh grid hole 803, positioning part 804. Detailed implementation manners

[0023] The present utility model will be further described below in conjunction with embodiments and the accompanying drawings.

[0024] In the embodiment, as Figures 1 to 4 shown, it is a consumable for automated preparation of PRP centrifugal extraction, specifically including an outer tube body 1, a top cover 2, a base 3 and an internally placed central liquid extraction tube 4. The top cover 2 is provided with an injection port 201, a suction port 202 and a ventilation port 203. The upper end of the central liquid extraction tube 4 is communicated with the suction port 202, and the lower end forms a liquid extraction port 401 inside the outer tube body 1. The lower end inside the outer tube body 1 is provided with a sealed piston 5, and the base 3 is provided with an operation port 301. The piston 5 is made of medical-grade elastic materials such as rubber and silica gel, and other components of the consumable are made of medical-grade transparent materials such as PVC, PC, and ABS. Ultrasonic welding / adhesive bonding processes are used for each connection part. Among them, the outer tube body 1 and the central liquid extraction tube 4 are similar in structure to those in the patent document CN216678283U. The outer tube body 1 is divided into upper and lower chambers and a throat chamber in the middle. The lower end of the central liquid extraction tube 4 is located at the throat chamber. Rubber plugs are provided in the injection port 201 and the suction port 202, and a bacteria-proof membrane is provided in the ventilation port 203. In this embodiment, the position of the demarcation liquid surface between red blood cells and PRP is changed by the axial movement of the piston 5, which simplifies the structure of the consumable itself and reduces the cost; on this basis, the piston 5 is pushed by a linear motor-driven push rod mechanism through the operation port 301, so that the automatic adjustment of the demarcation liquid surface can be realized without setting complex positioning and clamping structures, greatly simplifying the structure of the liquid surface adjustment device, reducing the cost of the automatic equipment, and ensuring the accuracy of the demarcation liquid surface adjustment.

[0025] In the embodiment, as Figure 2 , 4 shown, it further includes a mounting seat 6 and an adjusting seat 7. The mounting seat 6 and the piston 5 are assembled into an integral structure. The mounting seat 6 is exposed from the operation port 301. One end of the exposed mounting seat 6 is provided with a pushing tapered hole 601. The adjusting seat 7 and the mounting seat 6 are detachably connected by threads. The adjusting seat 7 of this embodiment plays a role in reference adjustment for the piston 5, that is, before leaving the factory, by pulling the adjusting seat 7 outwards, the piston 5 is made to contact the base 3, ensuring the consistency of the position of the piston 5 when the consumable leaves the factory, that is, the internal effective volume of the consumable is the same. And after injecting whole blood and before centrifugation starts, the adjusting seat 7 is detached from the mounting seat 6 by rotation, so that the push rod mechanism directly acts on the mounting seat 6 during the subsequent adjustment process to ensure sufficient adjustment stroke. In another embodiment, as Figure 5 shown, the adjusting seat 7 and the mounting seat 6 are connected by a rotary buckle. The end of the mounting seat 6 is provided with two rotary buckles extending radially, and the adjusting seat 7 is correspondingly provided with two rotary openings. When the adjusting seat 7 is rotated in the reverse direction to align the rotary openings with the rotary buckles, the adjusting seat 7 can be detached.

[0026] In the embodiment, as Figure 4 shown, the piston 5 is made of an elastic material such as medical-grade silicone. An inner card slot 502 is provided in the insertion hole 501 at the lower end of the piston 5, and the mounting seat 6 has an outer card slot 602. The piston 5 and the mounting seat 6 are inserted and clamped. The elastic piston 5 is convenient for installation with the mounting seat 6 and can achieve better sealing with the outer tube body 1. Moreover, the inner card slot 502 or the outer card slot 602 can be set as a polygonal structure, so that the piston 5 and the mounting seat 6 are circumferentially fixed after assembly to prevent relative rotation between the two.

[0027] In the embodiment, as Figure 1 , 2 shown, the cross-sections of the main body part of the outer tube body 1, the top cover 2, the base 3 and the adjusting seat 7 are polygons with the same shape. The polygonal structure facilitates the alignment of the edges, making production more convenient and the product appearance more beautiful. The welding lines on the inner surfaces of the upper and lower ports of the main body part of the outer tube body 1 are consistent with the external polygonal structure of the main body, so that workers do not need to confirm whether the upper cover main body and the lower cover are aligned during the welding and assembly processes, thus simplifying the operation.

[0028] In the embodiment, as Figure 3As shown in the figure, pressing plate grooves 204 are provided at positions corresponding to the injection port 201, the suction port 202 and the ventilation port 203 on the top cover 2. A pressing plate 8 is assembled in the pressing plate grooves 204. The pressing plate 8 is respectively provided with a first through hole 801, a second through hole 802 and a mesh grid hole 803 corresponding to the injection port 201, the suction port 202 and the ventilation port 203. The mesh grid hole 803 is used to distinguish the injection port 201 from the air port 203, which plays a prompting role for the operator to avoid the needle from being inserted into the ventilation port 203 and prevent clinical misoperation.

[0029] In the embodiment, as Figure 3 shown, a positioning portion 804 is provided on the surface of the pressing plate 8 facing the top cover 2, and a corresponding positioning port 205 is provided on the top cover 2. The positioning portion 804 adopts a non-circular columnar structure, and the corresponding positioning port 205 also adopts a non-circular hole, and they cooperate with each other to achieve a foolproof design, avoiding the worker from installing the mesh grid hole 803 on the pressing plate 8 in the wrong direction.

[0030] In the embodiment, as Figure 2 、 4 shown, there are two seals provided between the piston 5 and the outer tube body 1, that is, a first seal is provided between the outer peripheral wall of the piston 5 and the inner peripheral wall of the outer tube body 1, and a second seal is provided between the lower surface of the piston 5 and the upper surface of the base 3. Specifically, at least two seal rings grooves 503 for accommodating sealing rings are provided on the outer peripheral wall of the piston 5, and the sealing rings form the first seal; a V-shaped sealing protrusion 504 is provided at the bottom of the piston 5, and a corresponding V-shaped sealing groove opening 302 is provided on the base 3. The V-shaped sealing protrusion 504 and the V-shaped sealing groove opening 302 form the second seal. The multiple sealing structure is used to ensure good sealing performance, and the second seal mainly plays a sealing role during the centrifugation process. Before leaving the factory, by pulling the adjusting seat 7 outwards, the piston 5 is brought into contact with the base 3, that is, the V-shaped sealing protrusion 504 and the V-shaped sealing groove opening 302 maintain a preliminary seal; during centrifugation, the greater the centrifugal force, the closer the V-shaped sealing protrusion 504 fits with the V-shaped sealing groove opening 302, and the better the sealing effect, so the blood leakage situation in the high-speed centrifugation state can be eliminated.

[0031] Obviously, the above-mentioned embodiments of the present invention are only examples for explaining the present invention, rather than limiting the implementation manners of the present invention. Other obvious changes or variations derived from the essential spirit of the present invention still fall within the protection scope of the present invention.

Claims

1. A consumable for automated preparation of PRP by centrifugal extraction, comprising an outer tube body (1), a top cover (2), a base (3) and a built-in central liquid collection tube (4), wherein the top cover (2) is provided with an injection port (201), a suction port (202) and a vent (203), the upper end of the central liquid collection tube (4) is connected to the suction port (202), and the lower end forms a liquid collection port (401) in the outer tube body (1), characterized in that: A sealed piston (5) is provided inside the lower end of the outer tube body (1); an operating port (301) is provided on the base (3); a mounting seat (6) is connected to the piston (5); the mounting seat (6) is exposed from the operating port (301); and a push cone hole (601) is provided at one exposed end of the mounting seat (6).

2. The consumable material for automated preparation of PRP by centrifugal extraction according to claim 1, characterized in that: It also comprises an adjustment seat (7), wherein the adjustment seat (7) is detachably connected to the mounting seat (6).

3. The consumable material for automated preparation of PRP by centrifugal extraction according to claim 2, characterized in that: The adjustment seat (7) is connected to the mounting seat (6) via a threaded connection or a rotating buckle connection.

4. The consumable material for automated preparation of PRP by centrifugal extraction according to claim 2, characterized in that: The piston (5) is made of elastic material, an inner slot (502) is provided in the insertion hole (501) at the lower end of the piston (5), the mounting seat (6) has an outer slot (602), and the piston (5) and the mounting seat (6) are plugged and fixed.

5. The consumable material for automated preparation of PRP by centrifugal extraction according to claim 2, characterized in that: The cross-sections of the main body of the outer tube body (1), the top cover (2), the base (3) and the adjustment seat (7) are polygonal in shape.

6. The consumable material for automated preparation of PRP by centrifugal extraction according to claim 1, characterized in that: The vent (203) is provided with a mesh hole (803).

7. The consumable material for automated preparation of PRP by centrifugal extraction according to claim 6, characterized in that: A pressure plate groove (204) is provided on the top cover (2) at positions corresponding to the injection port (201), the suction port (202) and the vent (203); the pressure plate groove (204) is equipped with a pressure plate (8); and the pressure plate (8) is provided with a first through hole (801), a second through hole (802) and the mesh hole (803) corresponding to the injection port (201), the suction port (202) and the vent (203), respectively.

8. The consumable material for automated preparation of PRP by centrifugal extraction according to claim 7, characterized in that: A positioning portion (804) is provided on a side of the pressing plate (8) facing the top cover (2), and a positioning opening (205) is correspondingly provided on the top cover (2).

9. The consumable material for automated preparation of PRP by centrifugal extraction according to claim 1, characterized in that: A first seal is provided between the outer peripheral wall of the piston (5) and the inner peripheral wall of the outer tube body (1), and a second seal is provided between the lower surface of the piston (5) and the upper surface of the base (3).

10. The consumable material for automated preparation of PRP by centrifugal extraction according to claim 9, characterized in that: The outer peripheral wall of the piston (5) is provided with at least two sealing ring grooves (503) for accommodating sealing rings, and the sealing rings form the first seal; the bottom of the piston (5) is provided with a V-shaped sealing protrusion (504), and the base (3) is correspondingly provided with a V-shaped sealing notch (302), and the V-shaped sealing protrusion (504) and the V-shaped sealing notch (302) form the second seal.

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