Full-automatic multifunctional agglutination test workstation

Abstract

The utility model provides a full-automatic multifunctional agglutination test workstation, which relates to the field of animal epidemic disease detection, and adopts the technical scheme that the full-automatic multifunctional agglutination test workstation comprises a reaction table and a material table, the material table is positioned on one side of the reaction table, a sample area and / or a gun head area and / or a reagent area and / or a waste groove are arranged on the material table, a sample frame is detachably arranged in the sample area, and the sample frame is detachably arranged in the waste groove. A gun head box is arranged in the gun head area, a reagent container is detachably arranged in the reagent area, the reaction table is provided with a reagent area and / or a reaction area, the reaction area is detachably provided with a reaction plate, hole grooves are formed in the reaction plate, the lengths and the widths of the reaction plate, the sample frame and the reagent container are respectively the same, and the reaction table is connected with an oscillating unit and a swinging unit. And the oscillating unit and the swinging unit are electrically connected with the control unit respectively. According to the utility model, antibodies of various epidemic diseases such as brucellosis, avian influenza and the like can be detected, the universal detection level of the workstation is higher, and the equipment purchase cost investment is reduced.

Description

Technical Field

[0001] The utility model relates to the field of animal disease detection, in particular to a full-automatic multifunctional agglutination test workstation. Background Art

[0002] Animal diseases refer to infectious and parasitic diseases of animals, including Newcastle disease, brucellosis, pullorum, avian influenza, etc., which are serious hazards to humans and animals. Among them, those that require emergency, severe and compulsory prevention, control, and eradication measures are Class I diseases, which may cause major economic losses and require strict control and eradication measures to prevent their spread are Class II diseases, and those that are common and multiple, may cause major economic losses, and need to be controlled and purified are Class III diseases. The principle of prevention first is implemented for animal diseases, among which disease detection is a very important link.

[0003] In the prior art, a Chinese utility model patent with authorization announcement number CN217359930U discloses a heat source detector, including a frame, a sample carrying device and a reaction device arranged on the frame in sequence, and a sample transfer device is provided between the sample carrying device and the reaction device, which is used to transfer a single sample from the sample carrying device to the reaction device, thereby realizing the automation of the process of taking samples from the tiger red (brucellosis) plate agglutination test and mixing samples and reagents, improving the detection efficiency and reducing the risk of hospital infection; a Chinese invention patent with authorization announcement number CN105974145B discloses a fully automatic Newcastle disease detector, which realizes the automation of Newcastle disease detection and greatly improves the sampling efficiency; the fully automatic Newcastle disease detector is jointly controlled by a computer and a single-chip microcomputer, thereby avoiding errors caused by manual operation and improving the test accuracy.

[0004] In addition, since the detection of diseases such as brucellosis and pullorum adopts plate agglutination detection, while the detection of diseases such as avian influenza and Newcastle disease adopts blood agglutination detection, and the reagent types, storage conditions, reaction tube apertures, and detection steps of plate agglutination detection and blood agglutination detection are different, the layout of the corresponding reaction plates, reagent containers, and sample racks is quite different, as shown in the attached figure. Figure 1 and attached Figure 2 As shown, dedicated testing equipment is needed to complete the detection of diseases such as brucellosis, avian influenza, Newcastle disease and pullorum, which greatly increases the investment cost of the testing unit equipment and the utilization rate of various testing equipment is low. Utility Model Content

[0005] In order to solve the technical problem that the related equipment for brucellosis detection, avian influenza and Newcastle disease detection in the above-mentioned prior art cannot be used universally, the utility model provides a fully automatic multifunctional agglutination test workstation, which can complete the detection of brucellosis, avian influenza, Newcastle disease and other disease antibodies. The workstation has a high level of universal detection, reducing the cost investment in equipment procurement.

[0006] The utility model adopts the following technical solution to solve the above technical problems: a fully automatic multifunctional agglutination test workstation, comprising a reaction table and a material table, wherein the material table is located on one side of the reaction table, and a sample area and / or a gun tip area and / or a reagent area and / or a waste tank are arranged on the material table, a sample rack is detachably arranged in the sample area, a gun tip box is arranged in the gun tip area, a reagent container is detachably arranged in the reagent area, the reaction table is provided with a reagent area and / or a reaction area, a reaction plate is detachably arranged in the reaction area, a hole groove is arranged on the reaction plate, the reaction plate, the sample rack and the reagent container have the same length and width, the reaction table is connected with an oscillation unit and a swing unit, and the oscillation unit and the swing unit are electrically connected to a control unit respectively.

[0007] The utility model divides the material area and the reaction area into zones and adopts detachable reaction plates, sample racks and reagent containers with the same length and width. It can be laid out as required according to different detection contents, and can oscillate and tilt at a certain angle as required, so as to meet the needs of various disease antibody detection, improve the integration of disease detection and the universality of detection workstations, and reduce the purchase cost of equipment.

[0008] Furthermore, the gun tip box is detachably disposed in the gun tip area, and the gun tip box and the reaction plate have the same length and width.

[0009] The utility model arranges the gun tip box to match the length and width of the reaction plate, which can further enhance the flexibility of the layout of the reaction table and the material table of the workstation.

[0010] Furthermore, at least two reaction tables are provided, and the plurality of reaction tables are respectively connected to the corresponding swing units, and the plurality of reaction tables are respectively rotatably connected to an oscillation plate, and the oscillation plate is connected to the oscillation unit, and a mounting plate is provided at the lower part of the oscillation plate, and the mounting plate is provided on the bottom plate, and the swing unit is provided on the bottom plate.

[0011] Furthermore, the swing unit includes a swing motor, which is connected to a swing arm, and the swing arm can rotate in a vertical plane. A roller is provided at the end of the swing arm, and the roller can roll and rub against the bottom surface of the end of the reaction table. One side of the reaction table is hinged to the oscillation plate, and a limit stop arm is provided on the oscillation plate, and the limit stop arm can abut against the reaction table.

[0012] Furthermore, a limit bracket and a limit column are provided on the bottom plate, a limit switch is provided on the upper part of the limit bracket, a limit plate is provided on the end of the swing arm, the limit switch can sense the limit plate and send a corresponding electrical signal to the control unit, the top of the limit column can abut against the lower surface of the swing arm, and the height of the limit column and the limit switch is lower than the oscillation plate.

[0013] The limit switches and limit posts are used to form both electrical and mechanical limit measures, thereby improving the reliability of the swing arm limit and positioning.

[0014] Furthermore, the oscillation unit includes an oscillation motor and a belt transmission mechanism, the oscillation motor is connected to a transmission shaft through the belt transmission mechanism, the transmission shaft is rotatably disposed on the mounting plate, an eccentric wheel is disposed on the transmission shaft, and the eccentric wheel is connected to the oscillation plate.

[0015] Furthermore, the oscillation plate is of a rectangular structure, and eccentric support wheels are disposed at four corners of the oscillation plate, and the eccentric support wheels are rotatably disposed on the mounting plate.

[0016] The utility model can ensure the stable shaking of the oscillating plate and avoid imbalance by arranging a plurality of eccentric supporting wheels.

[0017] Furthermore, a limit clamping seat is also provided on the oscillation plate, and the limit clamping seat can be clamped with a clamping block at the bottom of the reaction table.

[0018] Furthermore, it also includes an image acquisition module, which includes a camera. The camera is swingably arranged on the mounting seat, the camera is electrically connected to the control unit, and a light panel is embedded on the bottom of the reaction table.

[0019] It can be seen from the above technical solutions that the utility model has the following advantages:

[0020] The utility model provides a fully automatic multifunctional agglutination test workstation, which can be laid out as required according to different detection contents by partitioning the material area and the reaction area and adopting detachable reaction plates, sample racks and reagent containers with the same length and width, and can be oscillated and tilted at a certain angle as required to meet the needs of various disease antibody detection, improve the integration of disease detection and the generalization of detection workstations, and reduce the purchase cost of equipment; the gun head box is set to the same length and width as the reaction plate to further enhance the flexibility of the layout of the reaction table and the material table of the workstation; the limit stop arm can limit the reaction plate after the reaction table is swung and tilted to prevent the reaction plate from tipping over; the limit switch and the limit column form two kinds of electrical and mechanical limit measures to improve the reliability of the swing arm limit; and the plurality of eccentric support wheels can ensure the stable shaking of the oscillation plate to avoid imbalance. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the technical solution of the utility model, the drawings required for use in the description will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0022] Figure 1 This is a schematic diagram of the layout of the plate agglutination test for brucellosis and pullorum.

[0023] Figure 2 Schematic diagram of the layout of the hemagglutination test for avian influenza and Newcastle disease.

[0024] Figure 3 It is a structural schematic diagram of a specific implementation method of the utility model.

[0025] Figure 4 It is a schematic diagram of the assembly structure of the reaction table, the material table, the oscillation unit and the swing unit in a specific implementation manner of the utility model.

[0026] Figure 5 It is a structural schematic diagram of a reaction platform in a specific implementation manner of the utility model.

[0027] Figure 6 It is a schematic diagram of the assembly structure of the reaction table, the material table, the oscillation unit and the swing unit in a specific implementation manner of the utility model.

[0028] Figure 7 It is a schematic diagram of the structure of the oscillation unit in a specific implementation manner of the utility model.

[0029] Figure 8 The assembly structure of the oscillating plate, the mounting plate and the bottom plate in the specific implementation mode of the utility model is shown in FIG. Figure 1 .

[0030] Fig. 9 The assembly structure of the oscillating plate, the mounting plate and the bottom plate in the specific implementation mode of the utility model is shown in FIG. Figure 2 .

[0031] Fig.10 It is a schematic diagram of the assembly structure of the camera and the adjustment bracket in a specific implementation manner of the utility model.

[0032] In the figure, 1. material table; 2. bottom plate; 3. waste trough; 4. gun tip box; 5. sample rack; 6. reaction table; 7. reaction plate; 8. reagent container; 9. limit seat 2; 10. limit seat 1; 11. limit support; 12. swing motor; 13. limit switch; 14. roller; 15. limit plate; 16. mounting plate; 17. oscillation plate; 18. oscillation motor; 19. belt transmission mechanism; 20. eccentric support wheel; 21. eccentric wheel; 22. camera; 23. adjustment bracket; 24. guide groove; 25. positioning bolt; 26. limit pin; 27. swing arm; 28. limit stop arm; 29. ​​positioning pin; 30. hinge; 31. limit holder; 32. pipette; 33. moving rod; 34. support beam. DETAILED DESCRIPTION

[0033] In order to make the purpose, features and advantages of the utility model more obvious and easy to understand, the technical scheme of the utility model will be clearly and completely described below in combination with the drawings in the specific embodiment. Obviously, the embodiments described below are only part of the embodiments of the utility model, not all of them. Based on the embodiments in this patent, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this patent.

[0034] like Figures 3 to 6 As shown, this specific embodiment provides a fully automatic multifunctional agglutination test workstation, including a reaction table 6 and a material table 1, the material table 1 is located on one side of the reaction table 6, and a sample area and / or a gun tip area and / or a reagent area and / or a waste tank 3 are arranged on the material table 1, a sample rack 5 is detachably arranged in the sample area, a gun tip box 4 is arranged in the gun tip area, and a reagent container 8 is detachably arranged in the reagent area, the reaction table 6 is provided with a reagent area and / or a reaction area, a reaction plate 7 is detachably arranged in the reaction area, and a hole groove is arranged on the reaction plate 7, and the length and width of the reaction plate 7, the sample rack 5 and the reagent container 8 are respectively the same. In order to further enhance the flexibility of the layout of the reaction table 6 and the material table 1 of this workstation, the gun tip box 4 is detachably arranged in the gun tip area, and the length and width of the gun tip box 4 and the reaction plate 7 are respectively the same; the reaction table 6 is connected to an oscillation unit and a swing unit, and the oscillation unit and the swing unit are respectively electrically connected to the control unit.

[0035] This specific embodiment divides the material area and the reaction area into zones and adopts a detachable reaction plate 7, a sample rack 5, a gun tip box 4 and a reagent container 8 of the same length and width. It can be reasonably arranged according to the requirements of different disease detection. On the one hand, it meets the needs of different reagent supply and avoids contamination caused by the dripping of reagents and samples when the pipette is working. On the other hand, it also takes into account the detection efficiency and oscillates and tilts the reaction plate 7 and the reagent container 8 at a certain angle according to the detection requirements to meet the needs of various disease antibody detection, improve the integration of disease detection and the universality of detection workstations, and reduce the purchase cost of equipment.

[0036] like Figure 5 and Figure 6 As shown, in this specific embodiment, the material table 1 is provided with a sample area, a gun tip area, a reagent area and a waste tank 3, that is, a sample rack 5, a gun tip box 4 and a reagent container 8 are provided. The material table 1 is divided into zones by a limit seat 10 and a limit seat 2 9. The limit seat 10 is a cross-shaped structure, and the limit seat 2 9 is an L-shaped structure. The limit seat 10 and the limit seat 2 9 are both in contact with the outer wall of the adjacent sample rack 5, reagent container 8 or gun tip box 4 and can generate static friction and sliding friction. The friction generated by the limit seat 9 is detachably installed, and the waste trough 3 is set on the material table 1 by bolts; the reaction table 6 is divided into sections by the limit support 11, and a reagent container 8 and a reaction plate 7 are arranged on the reaction table 6. A spring pin is horizontally arranged on the inner wall of the limit support 11, and the spring pin can abut against the reaction plate 7 and the reagent container 8. By setting the spring pin, the reaction plate 7 can be placed conveniently on the one hand, and at the same time, it can ensure that the reaction plate 7 is reliably limited to prevent it from falling off when the reaction table 6 is in a tilted state.

[0037] like Figure 4 and Figure 6 As shown, in order to improve the detection efficiency, at least two reaction tables 6 are provided, and the multiple reaction tables 6 are respectively connected to the corresponding swing units. In the present specific embodiment, two reaction tables 6 are provided, and the multiple reaction tables 6 are respectively rotatably connected to the oscillation plate 17, the oscillation plate 17 is connected to the oscillation unit, a limit stop arm 28 is provided on the oscillation plate 17, and the limit stop arm 28 can abut against the reaction table 6, a mounting plate 16 is provided at the lower part of the oscillation plate 17, the mounting plate 16 is provided on the bottom plate 2, the swing unit is provided on the bottom plate 2, and the two swing units are provided on both sides of the oscillation unit, and the material table 1 is also supported on the bottom plate 2.

[0038] like Figure 6 and Figure 7As shown, preferably, in this specific embodiment, the swing unit can adopt the following specific structure: the swing unit includes a swing motor 12, the swing motor 12 is arranged on the bottom plate 2, the swing motor 12 is connected to a swing arm 27, the swing arm 27 can rotate in a vertical plane, one side of the reaction table 6 is hinged to the oscillation plate 17 through a hinge 30, when the swing arm 27 rotates, it can contact the reaction table 6, and push the reaction table 6 to rotate with the hinge as the center of the circle, in order to reduce friction and wear, a roller 14 is arranged at the end of the swing arm 27, and the roller 14 can roll and rub with the bottom surface of the end of the reaction table 6; in order to be able to It is able to improve the ability of limiting and positioning the swing arm 27 to avoid interference with the oscillation of the reaction table 6. A limit bracket and a limit column are arranged on the bottom plate 2. A limit switch 13 is arranged on the upper part of the limit bracket. The limit switch 13 adopts a normally closed proximity switch. A limit plate 15 is arranged at the end of the swing arm 27. The limit switch 13 can sense the limit plate 15 and send a corresponding electrical signal to the control unit when sensing the limit plate 15. The control unit controls the swing motor 12 to stop working. The top of the limit column can abut against the lower surface of the swing arm 27. The heights of the limit column and the limit switch 13 are both lower than the oscillation plate 17.

[0039] like Figure 8 and Fig. 9 As shown, preferably, in this specific embodiment, the oscillation unit can adopt the following specific structure: the oscillation unit includes an oscillation motor 18 and a belt transmission mechanism 19, the oscillation motor 18 is connected to a transmission shaft through the belt transmission mechanism 19, the transmission shaft is rotatably arranged on the mounting plate 16 through a bearing, an eccentric wheel 21 is arranged on the transmission shaft, the eccentric wheel 21 is connected to the oscillation plate 17, and when the eccentric wheel 21 rotates, it can drive the oscillation plate 17 to rotate and realize oscillation; in order to ensure the stability of the oscillation plate 17, the oscillation plate 17 is of a rectangular structure, and eccentric support wheels 20 are arranged at the four corners of the oscillation plate 17, and the eccentric support wheels 20 are rotatably arranged on the mounting plate 16 through a rotating shaft and a bearing; since there is a gap in the hinge connection between the reaction table 6 and the oscillation plate 17, the hinge 30 is subjected to torque during the oscillation process, and in order to reduce the torque on the hinge 30 and prevent deformation, a limit card seat 31 is also arranged on the oscillation plate 17, and the limit card seat 31 can be engaged with the card block at the bottom of the reaction table 6 to ensure that the reaction table 6 and the oscillation plate 17 move synchronously during oscillation.

[0040] like Figure 1 and Fig.10As shown, in order to further realize automation, this specific embodiment also includes a pipette gun 32, which is arranged on a mounting seat, and the mounting seat is movably arranged on a moving rod 33 through a slide rail and is connected to a driving unit 1, and the moving rod 33 is movably arranged on a support beam 34 through a slide rail and is connected to a driving unit 2, and the mounting seat is perpendicular to the direction of movement of the moving rod 33, and the pipette gun 32, the driving unit 1 and the driving unit 2 are all electrically connected to the control unit; this specific embodiment also includes an image acquisition module, and the image acquisition module includes a camera 22. Due to the different inclination angles of the reaction table 6 when acquiring images for different disease detection, in order to acquire images more clearly, the camera 22 is adjusted by adjusting the bracket 2 3 is swingably arranged on the mounting seat, and the camera 22 is provided with a positioning bolt 25 to fix the position. According to the disease detection type and detection requirements of this workbench, a 45° limit pin 26 and a 60° limit pin 26 are provided on the adjustment bracket 23, and an arc-shaped guide groove 24 is provided. When adjusting, the positioning bolt 25 is loosened, and the camera 22 is rotated until the positioning pin 29 on the camera 22 abuts against the corresponding limit pin 26, and then the positioning bolt 25 is tightened. The camera 22 is electrically connected to the control unit. A light panel is embedded on the bottom of the reaction table 6, and the limit support 11 has no bottom and is a frame structure. The light panel can enhance the light intensity at the bottom of the reaction plate 7, which is convenient for image acquisition.

[0041] The working process of this fully automatic multifunctional agglutination test workstation is:

[0042] First, the reaction table 6 and the material table 1 are arranged according to the requirements of the disease antibodies to be detected, and then the steps of sampling, adding reagents, oscillating, image acquisition and judgment are carried out in sequence according to the national or international standards for the corresponding disease antibody detection.

[0043] From the above specific implementations, it can be seen that the utility model has the following beneficial effects:

[0044] 1. By partitioning the material area and the reaction area and using detachable reaction plates 7, sample racks 5 and reagent containers 8 of the same length and width, the layout can be carried out according to the requirements of different detection contents, and oscillate and tilt at a certain angle as required, so as to meet the needs of various disease antibody detection, improve the integration of disease detection and the universality of detection workstations, and reduce the purchase cost of equipment;

[0045] 2. Setting the gun tip box 4 to the same length and width as the reaction plate 7 can further enhance the flexibility of the layout of the reaction table 6 and the material table 1 of this workstation;

[0046] 3. The limiting arm 28 can limit the reaction plate 7 after the reaction table 6 swings and tilts, thereby preventing the reaction plate 7 from falling over;

[0047] 4. The limit switch 13 and the limit column form two kinds of limit measures, namely electrical and mechanical, to improve the reliability of the limit of the swing arm 27;

[0048] 5. By providing a plurality of eccentric support wheels 20, the oscillation plate 17 can be ensured to shake stably and avoid imbalance.

[0049] The above description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but will conform to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A fully automatic multifunctional agglutination test workstation, comprising a reaction table (6) and a material table (1), characterized in that: The material table (1) is located on one side of the reaction table (6); a sample area and / or a gun tip area and / or a reagent area and / or a waste tank (3) are arranged on the material table (1); a sample rack (5) is detachably arranged in the sample area; a gun tip box (4) is arranged in the gun tip area; a reagent container (8) is detachably arranged in the reagent area; the reaction table (6) is provided with a reagent area and / or a reaction area; a reaction plate (7) is detachably arranged in the reaction area; a hole groove is arranged on the reaction plate (7); the length and width of the reaction plate (7), the sample rack (5) and the reagent container (8) are respectively the same; the reaction table (6) is connected to an oscillating unit and a swinging unit; and the oscillating unit and the swinging unit are respectively electrically connected to a control unit.

2. The fully automatic multifunctional agglutination test workstation according to claim 1, characterized in that: The gun tip box (4) is detachably arranged in the gun tip area, and the gun tip box (4) and the reaction plate (7) have the same length and width.

3. The fully automatic multifunctional agglutination test workstation according to claim 2, characterized in that: At least two reaction tables (6) are provided, and the plurality of reaction tables (6) are respectively connected to corresponding swing units, and the plurality of reaction tables (6) are respectively rotatably connected to an oscillation plate (17), and the oscillation plate (17) is connected to the oscillation unit. A mounting plate (16) is provided at the lower part of the oscillation plate (17), and the mounting plate (16) is provided on the bottom plate (2), and the swing unit is provided on the bottom plate (2).

4. The fully automatic multifunctional agglutination test workstation according to claim 3, characterized in that: The swing unit comprises a swing motor (12), the swing motor (12) is connected to a swing arm (27), the swing arm (27) can rotate in a vertical plane, a roller (14) is arranged at the end of the swing arm (27), the roller (14) can roll and rub with the bottom surface of the end of the reaction table (6), one side of the reaction table (6) is hinged to the oscillation plate (17), a limit stop arm (28) is arranged on the oscillation plate (17), and the limit stop arm (28) can abut against the reaction table (6).

5. The fully automatic multifunctional agglutination test workstation according to claim 4, characterized in that: A limit bracket and a limit column are arranged on the bottom plate (2); a limit switch (13) is arranged on the upper part of the limit bracket; a limit plate (15) is arranged at the end of the swing arm (27); the limit switch (13) can sense the limit plate (15) and send a corresponding electrical signal to the control unit; the top of the limit column can abut against the lower surface of the swing arm (27); and the height of the limit column and the limit switch (13) is lower than that of the oscillating plate (17).

6. The fully automatic multifunctional agglutination test workstation according to any one of claims 3 to 5, characterized in that: The oscillation unit comprises an oscillation motor (18) and a belt transmission mechanism (19). The oscillation motor (18) is connected to a transmission shaft via the belt transmission mechanism (19). The transmission shaft is rotatably arranged on a mounting plate (16). An eccentric wheel (21) is arranged on the transmission shaft. The eccentric wheel (21) is connected to an oscillation plate (17).

7. The fully automatic multifunctional agglutination test workstation according to claim 6, characterized in that: The oscillating plate (17) is of rectangular structure. The four corners of the oscillating plate (17) are all provided with eccentric supporting wheels (20). The eccentric supporting wheels (20) are rotatably arranged on the mounting plate (16).

8. The fully automatic multifunctional agglutination test workstation according to claim 7, characterized in that: A limit clamping seat (31) is also provided on the oscillating plate (17), and the limit clamping seat (31) can be clamped with a clamping block at the bottom of the reaction table (6).

9. The fully automatic multifunctional agglutination test workstation according to claim 1, characterized in that: It also includes an image acquisition module, which includes a camera (22). The camera (22) is swingably arranged on a mounting seat, and the camera (22) is electrically connected to a control unit. A light panel is embedded on the bottom of the reaction table (6).

Images