Bulk drug separation and purification device

Abstract

The utility model discloses a bulk drug separation and purification device which comprises a supporting frame, a bottom plate is fixedly connected to the upper surface of the supporting frame, an outer cylinder and an inner cylinder are fixedly connected to the upper surface of the bottom plate, a stirring device is arranged in the inner cylinder, a collecting box is arranged in the outer cylinder and the inner cylinder, and the collecting box is communicated with the inner cylinder through a purification mechanism. A component detector is arranged on the collecting box, a top plate is fixedly connected to the upper surface of the outer cylinder, a water tank is fixedly connected to the upper surface of the top plate, a liquid pump is fixedly connected to the side surface of the water tank, the liquid pump communicates with the outer cylinder through a water inlet pipe, and a refrigerator is arranged on the water inlet pipe; the side surface of one side, far away from the liquid pump, of the water tank is fixedly connected with a water outlet pipe, the water outlet pipe is communicated with the outer cylinder, and through the structure, when some toxic raw material medicines are separated and purified, the situation that the toxic raw material medicines are leaked due to damage of the device, and the surrounding environment and personnel are harmed can be avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of separation and purification devices for bulk drugs, and particularly relates to a separation and purification device for bulk drugs. Background Art

[0002] In the existing separation and purification devices for bulk drugs, when separating and purifying some highly toxic drugs, the drugs are likely to leak due to reasons such as device damage, which is likely to cause harm to the surrounding environment and personnel. For example, the Chinese patent discloses "a separation and purification device for the synthesis of bulk drugs", with the application number: "CN202120023428.3", which includes a box body and a collection box. The upper end of the box body is fixedly connected with an upper cover, the upper end of the upper cover is fixedly connected with a first shell, the lower end of the box body is fixedly connected with a second shell, and a stirring mechanism for stirring the liquid medicine is arranged in the box body. The stirring mechanism includes a second motor fixedly connected to the bottom of the inner part of the second shell, and the output shaft of the second motor is fixedly connected with a rotating cylinder. Through the above structure, the quality of liquid medicine separation and purification is improved. However, when in use, when separating and purifying some highly toxic drugs, the drugs are likely to leak due to reasons such as device damage, which is likely to cause harm to the surrounding environment and personnel, and there are limitations in use. Summary of the Utility Model

[0003] The purpose of the utility model is to solve at least one of the technical problems existing in the prior art, and provide a separation and purification device for bulk drugs. By setting an outer cylinder, an inner cylinder, a stirring device, a collection box, a component detector, a top plate, a water tank, a liquid pump, a water inlet pipe, a refrigerator, and a water outlet pipe, through the above structure, when separating and purifying some toxic bulk drugs, it can avoid leakage due to device damage and cause harm to the surrounding environment and personnel.

[0004] The utility model also provides the above-mentioned separation and purification device for bulk drugs, including: a support frame, the upper surface of the support frame is fixedly connected with a bottom plate, the upper surface of the bottom plate is fixedly connected with an outer cylinder and an inner cylinder, a stirring device is arranged inside the inner cylinder, a collection box is arranged in the outer cylinder and the inner cylinder, the collection box is connected with the inner cylinder through a purification mechanism, a component detector is arranged on the collection box, the upper surface of the outer cylinder is fixedly connected with a top plate, the upper surface of the top plate is fixedly connected with a water tank, a liquid pump is fixedly connected to the side surface of the water tank, the liquid pump is connected with the outer cylinder through a water inlet pipe, a refrigerator is arranged on the water inlet pipe, the side surface of the water tank far away from the liquid pump is fixedly connected with a water outlet pipe, and the water outlet pipe is connected with the outer cylinder. Through the above structure, when separating and purifying some toxic bulk drugs, it can avoid leakage due to device damage and cause harm to the surrounding environment and personnel.

[0005] A separation and purification device for bulk drugs according to the present utility model, wherein the stirring device includes a motor, the motor is fixedly connected to the lower surface of the bottom plate, the output end of the motor is fixedly connected to a rotating shaft, and the side surface of the rotating shaft is fixedly connected with stirring blades. Through the above structure, the stirring blades can be driven to rotate, facilitating the stirring of the bulk drugs and making the heating more sufficient.

[0006] A separation and purification device for bulk drugs according to the present utility model, wherein the purification mechanism includes a heating plate, the heating plate is fixedly connected to the inner wall of the inner cylinder, and a temperature sensor adapted to the heating plate is arranged in the inner cylinder. Through the above structure, it is convenient to heat the raw materials and turn the bulk drugs into steam.

[0007] A separation and purification device for bulk drugs according to the present utility model, wherein the purification mechanism further includes a steam delivery pipe, the steam delivery pipe is fixedly connected to the side surface of the inner cylinder near the top plate and is communicated with the inner cylinder, one end of the steam delivery pipe away from the inner cylinder is fixedly connected with a distribution plate, the lower surface of the distribution plate is fixedly connected with a chromatographic column, and the bottom end of the chromatographic column is fixedly connected with a collection box. Through the above structure, the separated and purified bulk drugs at the separation edge can be collected.

[0008] A separation and purification device for bulk drugs according to the present utility model, wherein a partition plate is fixedly connected to the side surface of the inner cylinder, one end of the partition plate away from the inner cylinder is fixedly connected to the inner wall of the outer cylinder, and the steam delivery pipe penetrates through the partition plate and extends below the partition plate. Through the above structure, it is convenient to condense the bulk drug steam delivered by the steam delivery pipe.

[0009] A separation and purification device for bulk drugs according to the present utility model, wherein a feed pipe is fixedly connected to the top plate, the feed pipe penetrates through the water tank and the top plate and is communicated with the inside of the inner cylinder. Through the above structure, it is convenient to transport the mixture of bulk drugs into the inner cylinder.

[0010] A separation and purification device for bulk drugs according to the present utility model, wherein a first discharge pipe is fixedly connected to the lower surface of the bottom plate, the first discharge pipe penetrates through the bottom plate and is communicated with the collection box, and a solenoid valve is arranged on the first discharge pipe. Through the above structure, it is convenient to take out the drugs collected in the collection box.

[0011] A separation and purification device for bulk drugs according to the present utility model, wherein a second discharge pipe is fixedly connected to the lower surface of the bottom plate, the second discharge pipe penetrates through the bottom plate and is communicated with the inner cylinder, and a solenoid valve is arranged on the second discharge pipe. Through the above structure, it is convenient to discharge the waste liquid in the inner cylinder.

[0012] Beneficial effects

[0013] Compared with the prior art, for this raw drug separation and purification device, by providing an outer cylinder, an inner cylinder, a stirring device, a collection box, a component detector, a top plate, a water tank, a liquid pump, a water inlet pipe, a refrigerator, and a water outlet pipe, with the above structure, when separating and purifying some toxic raw drugs, it can avoid leakage caused by device damage and harm to the surrounding environment and personnel. Brief Description of the Drawings

[0014] The following further describes the present invention in conjunction with the drawings and embodiments;

[0015] Figure 1 It is the overall structure diagram of a raw drug separation and purification device of the present invention;

[0016] Figure 2 It is the bottom view structure diagram of a raw drug separation and purification device of the present invention;

[0017] Figure 3 It is the transverse sectional structure diagram of a raw drug separation and purification device of the present invention;

[0018] Figure 4 It is the longitudinal sectional structure diagram of a raw drug separation and purification device of the present invention.

[0019] Legend Explanation:

[0020] 1. Support frame; 2. Bottom plate; 3. Outer cylinder; 4. Top plate; 5. Water tank; 6. Water outlet pipe; 7. Water inlet pipe; 8. Refrigerator; 9. Liquid pump; 10. Feed pipe; 11. Motor; 12. First discharge pipe; 13. Rotating shaft; 14. Stirring blade; 15. Heating plate; 16. Collection box; 17. Chromatographic column; 18. Distribution plate; 19. Steam delivery pipe; 20. Partition board; 21. Inner cylinder; 22. Second discharge pipe; 23. Component detector. Specific Embodiments

[0021] This part will describe the specific embodiments of the present invention in detail. The preferred embodiments of the present invention are shown in the drawings. The role of the drawings is to supplement the description in the text part of the specification, enabling people to intuitively and vividly understand each technical feature and the overall technical solution of the present invention, but it cannot be understood as a limitation on the protection scope of the present invention.

[0022] Refer to Figures 1-4, an embodiment of the utility model provides a device for separating and purifying bulk drugs, which includes: a support frame 1, a bottom plate 2 fixedly connected to the upper surface of the support frame 1, an outer cylinder 3 and an inner cylinder 21 fixedly connected to the upper surface of the bottom plate 2. The outer cylinder 3 and the inner cylinder 21 are fixed. A stirring device is arranged inside the inner cylinder 21 to facilitate stirring of the bulk drugs. A collection box 16 is arranged inside the outer cylinder 3 and the inner cylinder 21. The collection box 16 is connected to the inner cylinder 21 through a purification mechanism to facilitate collection of the separated liquid medicine. A composition detector is arranged on the collection box 16 to detect the components in the water. A top plate 4 is fixedly connected to the upper surface of the outer cylinder 3, and a water tank 5 is fixedly connected to the upper surface of the top plate 4 to store water. A liquid pump 9 is fixedly connected to the side surface of the water tank 5. The liquid pump 9 is connected to the outer cylinder 3 through a water inlet pipe 7 to facilitate pumping out the water between the outer cylinder 3 and the inner cylinder 21. A cooler 8 is arranged on the water inlet pipe 7 to cool the water. An outlet pipe 6 is fixedly connected to the side surface of the water tank 5 away from the liquid pump 9. The outlet pipe 6 is connected to the outer cylinder 3 to facilitate transporting the water to the space between the outer cylinder 3 and the inner cylinder 21.

[0023] The stirring device includes a motor 11, which is fixedly connected to the lower surface of the bottom plate 2. The output end of the motor 11 is fixedly connected to a rotating shaft 13 to drive the rotation of the rotating shaft 13. Stirring blades 14 are fixedly connected to the side surface of the rotating shaft 13 to stir the bulk drugs. The purification mechanism includes a heating plate 15, which is fixedly connected to the inner wall of the inner cylinder 21. A temperature sensor adapted to the heating plate 15 is arranged inside the inner cylinder 21 to facilitate heating of the bulk drugs and control the temperature at the same time to avoid affecting the quality of the liquid medicine. The purification mechanism also includes a steam delivery pipe 19 to facilitate steam delivery. The steam delivery pipe 19 is fixedly connected to the side surface of the inner cylinder 21 close to the top plate 4 and is connected to the inner cylinder 21. One end of the steam delivery pipe 19 away from the inner cylinder 21 is fixedly connected to a distribution plate 18. The distribution plate 18 is fixed. Chromatographic columns 17 are fixedly connected to the lower surface of the distribution plate 18. The bottom ends of the chromatographic columns 17 are fixedly connected to the collection box 16 to facilitate fixing the chromatographic columns 17. A partition plate 20 is fixedly connected to the side surface of the inner cylinder 21. One end of the partition plate 20 away from the inner cylinder 21 is fixedly connected to the inner wall of the outer cylinder 3. The partition plate 20 is fixed. The steam delivery pipe 19 penetrates through the partition plate 20 and extends below the partition plate 20 to facilitate the water flow between the outer cylinder 3 and the inner cylinder 21 to condense the steam. A feed pipe 10 is fixedly connected to the top plate 4. The feed pipe 10 penetrates through the water tank 5 and the top plate 4 and is connected to the inside of the inner cylinder 21 to facilitate injecting the bulk drugs into the inner cylinder 21. A first discharge pipe 12 is fixedly connected to the lower surface of the bottom plate 2. The first discharge pipe 12 penetrates through the bottom plate 2 and is connected to the collection box 16. An electromagnetic valve is arranged on the first discharge pipe 12 to facilitate taking out the liquid medicine collected in the collection box 16. A second discharge pipe 22 is fixedly connected to the lower surface of the bottom plate 2. The second discharge pipe 22 penetrates through the bottom plate 2 and is connected to the inner cylinder 21. An electromagnetic valve is arranged on the second discharge pipe 22 to facilitate discharging the waste liquid inside the inner cylinder 21.

[0024] Working principle: During use, the mixture of the active pharmaceutical ingredients is injected into the inner cylinder 21 from the feed pipe 10. The motor 11 drives the stirring blade 14 to rotate to stir the active pharmaceutical ingredients. The heating plate 15 heats the active pharmaceutical ingredients to turn the raw materials into steam, which is transported to the distribution plate 18 through the steam delivery pipe 19 for uniform distribution. At the same time, when the steam delivery pipe 19 transports steam, the liquid pump 9 and the refrigerator work to keep the water flow between the outer cylinder 3 and the inner cylinder 21 in a flowing state and cool it, condensing the steam to make it better uniformly distributed on the distribution plate 18. Then it is separated through the chromatographic column 17 for re-purification, and finally transported to the collection box 16 for collection. The waste liquid in the inner cylinder 21 can be discharged through the second discharge pipe 22, and the liquid medicine in the collection box 16 can be discharged through the first discharge pipe 12. When a leakage occurs, the composition detector 23 detects a change in the components in the water, and a prompt can be given through an additional alarm device.

[0025] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those of ordinary skill in the art, various changes can be made without departing from the gist of the present invention.

Claims

1. A device for separating and purifying raw materials, characterized in that: include: A support frame (1), the upper surface of the support frame (1) is fixedly connected to a bottom plate (2), the upper surface of the bottom plate (2) is fixedly connected to an outer cylinder (3) and an inner cylinder (21), a stirring device is arranged in the inner cylinder (21), a collecting box (16) is arranged in the outer cylinder (3) and the inner cylinder (21), the collecting box (16) is connected to the inner cylinder (21) through a purification mechanism, a component detector (23) is arranged on the collecting box (16), the outer cylinder ( 3) A top plate (4) is fixedly connected to the upper surface of the top plate (4), a water tank (5) is fixedly connected to the upper surface of the top plate (4), a liquid pump (9) is fixedly connected to the side surface of the water tank (5), the liquid pump (9) is connected to the outer cylinder (3) through a water inlet pipe (7), a refrigerator (8) is arranged on the water inlet pipe (7), a water outlet pipe (6) is fixedly connected to the side surface of the water tank (5) away from the liquid pump (9), and the water outlet pipe (6) is connected to the outer cylinder (3).

2. A bulk drug separation and purification device according to claim 1, characterized in that: The stirring device comprises a motor (11), wherein the motor (11) is fixedly connected to the lower surface of the bottom plate (2), a rotating shaft (13) is fixedly connected to the output end of the motor (11), and a stirring blade (14) is fixedly connected to the side surface of the rotating shaft (13).

3. A bulk drug separation and purification device according to claim 1, characterized in that: The purification mechanism comprises a heating plate (15), wherein the heating plate (15) is fixedly connected to the inner wall of the inner cylinder (21), and a temperature sensor adapted to the heating plate (15) is arranged in the inner cylinder (21).

4. A bulk drug separation and purification device according to claim 1, characterized in that: The purification mechanism further comprises a steam delivery pipe (19), wherein the steam delivery pipe (19) is fixedly connected to the side surface of the inner cylinder (21) close to the top plate (4) and is in communication with the inner cylinder (21); an end of the steam delivery pipe (19) away from the inner cylinder (21) is fixedly connected to a distribution plate (18); a lower surface of the distribution plate (18) is fixedly connected to a chromatographic column (17); and a bottom end of the chromatographic column (17) is fixedly connected to a collection box (16).

5. A bulk drug separation and purification device according to claim 4, characterized in that: A partition (20) is fixedly connected to the side surface of the inner cylinder (21); one end of the partition (20) away from the inner cylinder (21) is fixedly connected to the inner wall of the outer cylinder (3); and the steam delivery pipe (19) passes through the partition (20) and extends to the bottom of the partition (20).

6. A bulk drug separation and purification device according to claim 1, characterized in that: A feed pipe (10) is fixedly connected to the top plate (4); the feed pipe (10) passes through the water tank (5) and the top plate (4), and is in communication with the inner cylinder (21).

7. A bulk drug separation and purification device according to claim 1, characterized in that: A first discharge pipe (12) is fixedly connected to the lower surface of the bottom plate (2); the first discharge pipe (12) passes through the bottom plate (2) and is connected to the collection box (16); and a solenoid valve is provided on the first discharge pipe (12).

8. A bulk drug separation and purification device according to claim 1, characterized in that: A second discharge pipe (22) is fixedly connected to the lower surface of the bottom plate (2); the second discharge pipe (22) passes through the bottom plate (2) and is connected to the inner tube (21); and a solenoid valve is provided on the second discharge pipe (22).

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