Agarose gel box convenient for cutting gel blocks
By introducing the design of adjusting channels, moving parts and clamping parts into the agarose gel box, the problem of inability to adjust the comb gap in the prior art is solved, and more convenient nucleic acid band observation and sample input are achieved.
Patent Information
- Application Number
- CN202421672745.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-16
- Publication Date
- 2025-06-03
- Estimated Expiration
- 2034-07-16
AI Technical Summary
In the existing agarose gel box, the gap between the comb teeth cannot be adjusted, which makes it inconvenient to observe the nucleic acid band and inconvenient to use.
An agarose gel box including adjustment channels, moving parts and clamps is designed, through which the spacing between adjacent comb teeth can be changed.
By adjusting the comb spacing, the observation of nucleic acid bands and the investment in samples are significantly facilitated, and the convenience of use is improved.
Smart Images
Figure CN222939049U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of gel boxes, in particular to an agarose gel box convenient for dividing gel blocks. Background Technique
[0002] Agarose gel electrophoresis technology is a common laboratory technology, which is widely used in separating proteins, nucleic acids, etc., especially in separating, purifying and identifying nucleic acids (DNA and RNA). This technology mainly uses agarose as the supporting medium. When stained with a low-concentration nucleic acid dye, nucleic acid bands of at least 1-10 ng can be detected under ultraviolet light, so as to determine the position of nucleic acid fragments in the gel. The preparation of agarose gel uses a diluted electrode buffer as the solvent, and a certain concentration of agarose sol is prepared by boiling water bath or microwave oven. The gel tray is placed in the gel maker, a gel comb with different gel hole sizes is inserted, poured into the horizontal gel tray, the comb is inserted, and it will become a gel after natural cooling. The comb is pulled out to form gel holes, and the sample is added to the gel holes to perform electrophoresis. In agarose gel operation, an agarose gel box is required.
[0003] In the existing technology, the agarose gel box includes a box body and a comb plate clamped and installed on the box body. The comb plate has comb teeth. Although it can meet the function of separating gel blocks, the comb teeth are fixedly connected, and the gap between the comb teeth cannot be adjusted, so it is not convenient to observe nucleic acid bands and is inconvenient to use. Content of the Utility Model
[0004] The purpose of the utility model is to solve the defects existing in the prior art, and to propose an agarose gel box convenient for dividing gel blocks. By setting an adjustment channel, a moving part and a clamping part, the distance between adjacent comb teeth can be changed, so as to facilitate the observation of nucleic acid bands and be convenient to use.
[0005] To achieve the above purpose, the utility model provides the following technical solution: an agarose gel box convenient for dividing gel blocks, including a box body, a card seat is fixedly connected to the side surface of the box body, a dividing component is arranged on the box body, the dividing component includes a dividing frame, a baffle is fixedly connected to the lower part of the dividing frame, an adjustment channel is arranged on the upper part of the dividing frame, a cross bar is fixedly connected to the upper surface of the dividing frame, a plurality of moving parts are arranged in the adjustment channel, the moving part includes a moving block slidably installed in the adjustment channel, a comb tooth is fixedly connected to the lower part of the moving block, a clamping part is fixedly connected to the upper part of the moving block, an arc part is arranged on the upper part of the clamping part, a clamping surface is arranged on the inner side of the clamping part, the cross bar passes through the clamping part, and the clamping surface is in contact with the cross bar. By setting an adjustment channel, a moving part and a clamping part, the distance between adjacent comb teeth can be changed, so as to facilitate the observation of nucleic acid bands and be convenient to use.
[0006] Further, the splitting frame and the card seat are engaged with each other. There are two card seats, and they are arranged axially symmetrically.
[0007] Further, the clamping member is made of an elastic material.
[0008] Further, the comb teeth are cuboids.
[0009] Further, the baffle is in contact with the inner wall of the box body.
[0010] Further, the baffle is located outside the comb teeth.
[0011] Further, the shape of the adjustment channel is strip-shaped.
[0012] Further, an anti-slip pad is fixedly connected to the clamping surface.
[0013] The utility model has the following beneficial effects:
[0014] An agarose gel box for facilitating the splitting of gel blocks proposed by the utility model can change the distance between adjacent comb teeth through the arranged adjustment channel, moving member and clamping member, so as to facilitate the observation of nucleic acid bands and is convenient to use. Description of the Drawings
[0015] Figure 1 is a schematic structural diagram of the split state of the utility model;
[0016] Figure 2 is a schematic structural diagram of the splitting component of the utility model;
[0017] Figure 3 is a schematic structural diagram of the moving member of the utility model;
[0018] Figure 4 is a schematic structural diagram of the clamping member of the utility model.
[0019] Legend Explanation:
[0020] 1. Box body; 101. Card seat; 2. Splitting component; 201. Splitting frame; 202. Baffle; 203. Cross bar; 204. Adjustment channel; 3. Moving member; 301. Comb teeth; 302. Moving block; 303. Clamping member; 3031. Arc part; 3032. Clamping surface. Detailed Embodiment
[0021] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.
[0022] Referring to Figures 1-4 , an embodiment provided by the present invention: an agarose gel box convenient for dividing gel blocks, including a box body 1, a card seat 101 is fixedly connected to the side surface of the box body 1, a dividing component 2 is arranged on the box body 1, the dividing component 2 includes a dividing frame 201, the dividing frame 201 is engaged with the card seat 101, the number of the card seats 101 is two and they are arranged axially symmetrically, a baffle 202 is fixedly connected to the lower part of the dividing frame 201, the baffle 202 is in contact with the inner wall of the box body 1, and the dividing frame 201 can be directly engaged with the card seat 101 to make the baffle 202 fully contact with the box body 1, thereby completing the blocking of the preparation solution;
[0023] The baffle 202 is located outside the comb teeth 301, an adjustment channel 204 is arranged on the upper part of the dividing frame 201, the shape of the adjustment channel 204 is strip-shaped, a cross bar 203 is fixedly connected to the upper surface of the dividing frame 201, a plurality of moving parts 3 are arranged in the adjustment channel 204, the moving parts 3 include moving blocks 302 slidably installed in the adjustment channel 204, a comb tooth 301 is fixedly connected to the lower part of the moving block 302, the comb tooth 301 is a cuboid, and the comb tooth 301 can divide the gel blocks of the agarose gel to form a sample input area. A clamping part 303 is fixedly connected to the upper part of the moving block 302, the clamping part 303 is made of an elastic material, an arc part 3031 is arranged on the upper part of the clamping part 303, the inner side of the clamping part 303 has a clamping surface 3032, an anti-slip pad is fixedly connected to the clamping surface 3032, the cross bar 203 passes through the clamping part 303, and the clamping surface 3032 is in contact with the cross bar 203.
[0024] When it is necessary to change the gap between the comb teeth 301, by changing the position of the moving block 302, the position of the comb teeth 301 can be changed, so as to conveniently change the distance between adjacent comb teeth 301, and good friction force is provided by the clamping part 303 and the clamping surface 3032, which can ensure the stability of the moving block 302, is convenient to use, and adjacent comb teeth 301 can also be combined together to form larger comb teeth 301 to provide a larger sample input area.
[0025] By arranging the adjustment channel 204, the moving parts 3 and the clamping part 303, the distance between adjacent comb teeth 301 can be changed, so as to conveniently observe the nucleic acid bands and is convenient to use.
[0026] Working principle: When in use, the splitting frame 201 can be directly snapped onto the card seat 101, enabling the baffle 202 to be in full contact with the box body 1, thus completing the blocking of the prepared solution. The comb teeth 301 can split the agarose gel block to form a sample input area. When it is necessary to change the gap between the comb teeth 301, by changing the position of the moving block 302, the position of the comb teeth 301 can be changed, thereby facilitating the change of the spacing between adjacent comb teeth 301. And through the clamping member 303 and the clamping surface 3032, good friction force is provided, which can ensure the stability of the moving block 302. It is convenient to use. Also, adjacent comb teeth 301 can be combined together to form larger comb teeth 301, providing a larger sample input area.
[0027] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.
Claims
1. An agarose gel box for facilitating the segmentation of gel blocks, comprising a box body (1), characterized in that: The side of the box body (1) is fixedly connected to a card seat (101), the box body (1) is provided with a partition assembly (2), the partition assembly (2) comprises a partition frame (201), the lower part of the partition frame (201) is fixedly connected to a baffle (202), the upper part of the partition frame (201) is provided with an adjustment channel (204), the upper surface of the partition frame (201) is fixedly connected to a cross bar (203), a plurality of moving parts (3) are provided in the adjustment channel (204), and the moving parts (3) are arranged in a plurality of movable parts (3) and a plurality of movable ... ) comprises a moving block (302) slidably mounted in an adjustment channel (204), the lower portion of the moving block (302) being fixedly connected with comb teeth (301), the upper portion of the moving block (302) being fixedly connected with a clamping member (303), the upper portion of the clamping member (303) being provided with an arc portion (3031), the inner side of the clamping member (303) being provided with a clamping surface (3032), the cross bar (203) passing through the clamping member (303), and the clamping surface (3032) being in contact with the cross bar (203).
2. The agarose gel box for facilitating the segmentation of gel blocks according to claim 1, characterized in that: The split frame (201) and the card seat (101) are mutually engaged, and there are two card seats (101) which are arranged in an axisymmetric manner.
3. The agarose gel box for facilitating the segmentation of gel blocks according to claim 1, characterized in that: The clamping member (303) is made of elastic material.
4. The agarose gel box for facilitating the segmentation of gel blocks according to claim 1, characterized in that: The comb teeth (301) are rectangular parallelepiped.
5. The agarose gel box for facilitating the segmentation of gel blocks according to claim 1, characterized in that: The baffle (202) is in contact with the inner wall of the box body (1).
6. The agarose gel box for facilitating the segmentation of gel blocks according to claim 1, characterized in that: The baffle (202) is located outside the comb teeth (301).
7. The agarose gel box for facilitating the segmentation of gel blocks according to claim 1, characterized in that: The adjustment channel (204) is in the shape of a long strip.
8. The agarose gel box for facilitating the segmentation of gel blocks according to claim 1, characterized in that: An anti-slip pad is fixedly connected to the clamping surface (3032).