Automatic blood sample injection treatment device

Abstract

The utility model discloses an automatic blood sample injection processing device, a blood sample is contained in a test tube, the test tube is inserted into a test tube rack, the test tube rack is driven by power to do linear motion, the automatic blood sample injection processing device comprises a sample uniform mixing mechanism, the sample uniform mixing mechanism comprises a uniform mixing assembly and a sample feeding mechanism, the test tube rubber sleeve is arranged below the supporting plate and rotationally connected with the supporting plate, the test tube rubber sleeve rotates under the driving of power, and the test tube rack can move to the position under the test tube rubber sleeve under the driving of the power; the moving assembly comprises a uniform mixing assembly mounting seat, the supporting plate is placed on the uniform mixing assembly mounting seat, a vertical guide structure is arranged between the uniform mixing assembly mounting seat and the supporting plate, and the uniform mixing assembly mounting seat is driven by power to move up and down. The utility model has the advantages of simple and compact structure and small volume, not only can reduce the cost, but also can save the installation space and facilitate the miniaturization of the instrument.

Description

Technical Field

[0001] The utility model relates to the technical field of in vitro diagnosis, and more specifically, to an automatic blood sample injection and processing device. Background Art

[0002] Currently, all the fully automatic chemiluminescence immunoassay analyzers on the market are medium-to-large chemiluminescence instruments with a high degree of automation and a measurement speed ranging from 100T / H to 600T / H. However, for clinical and a large number of primary hospitals, due to the limited sample volume, the utilization rate of medium-to-large instruments is low and the maintenance cost is high. In addition, the supporting reagents are 100 people / box. After the reagent box is opened, if it cannot be used up within a short period of time, it can only be discarded, which makes the cost of a single test higher. Moreover, for clinical use, the space for placing instruments is limited, and medium-to-large instruments cannot meet the requirements of clinical applications.

[0003] In order to meet the needs of clinical applications and grassroots hospitals, some manufacturers have launched miniaturized POCT single-person chemiluminescence immunoassay analyzers. However, in order to meet the miniaturization requirements of point of care testing (POCT) products, they have basically removed the complex automatic sampling mechanism on medium and large scales to reduce the overall volume of the instrument, and replaced it with a manual sampling design. The instrument cannot be fully automated, which affects the detection efficiency. Moreover, manual sampling is to manually add the sample to the designated sample well in advance, and the instrument then indirectly samples from the sample well. This requires that the amount of sample added manually must be more than the actual sampling amount of the instrument to avoid the problem of insufficient sampling due to sample hanging on the wall. The manual sampling method is not only complicated to operate and affects work efficiency, but also has problems such as sample waste caused by the need to use more sample volume in actual testing, and waste of disposable TIP consumables used for manual sampling.

[0004] Therefore, how to provide an automatic sample injection processing device with a simple structure, small size, and complete functions to solve the pain point that the miniaturized POCT single-portion chemiluminescence immunoassay analyzer requires manual sample addition and realize full automation of the instrument has become an urgent problem to be solved. Utility Model Content

[0005] The purpose of the utility model is to provide an automatic blood sample injection processing device, which has a simple and compact structure and a small size, which can not only reduce costs, but also save installation space and facilitate instrument miniaturization. Applying it to a POCT single-portion chemiluminescence immunoassay can solve the pain point that the current POCT single-portion chemiluminescence immunoassay has no automatic injection processing device and requires manual sample addition, thus realizing full automation of the instrument.

[0006] In order to achieve these purposes and other advantages of the utility model, an automatic blood sample injection processing device is provided. The blood sample is contained in a test tube, and the test tube is inserted into a test tube hole of a test tube rack. The test tube rack moves linearly under the driving force. The automatic blood sample injection processing device includes:

[0007] A sample mixing mechanism, comprising:

[0008] A mixing component, comprising:

[0009] Support plate;

[0010] The test tube rubber sleeve is arranged below the support plate and is rotatably connected to the support plate. The test tube rubber sleeve rotates under the driving force, and the test tube rack can move to the position directly below the test tube rubber sleeve under the driving force;

[0011] A mobile assembly comprising:

[0012] A mixing component mounting seat, the support plate is placed on the mixing component mounting seat, a vertical guide structure is arranged between the mixing component mounting seat and the support plate, and the mixing component mounting seat moves up and down under the driving force.

[0013] Preferably, the blood sample automatic sampling processing device further comprises:

[0014] A sample injection assembly comprising:

[0015] a test tube rack carrier, into which the test tube rack is inserted;

[0016] An injection guide rail, which is arranged on a fixed base;

[0017] An injection slide block is slidably arranged on the injection guide rail, and a test tube rack carrier is fixed on the injection slide block; a driving motor is arranged at one end of a fixed base;

[0018] A first driving pulley connected to an output end of the driving motor;

[0019] a first driven pulley rotatably disposed at the other end of the fixed base;

[0020] A first driving belt, which is arranged on the first driving pulley and the first driven pulley;

[0021] The card plate has one end clamped on the first driving belt and the other end connected to the side wall of the test tube rack carrier; when the driving motor drives the first active pulley to rotate, the first driving belt can drive the card plate to make a linear motion, and then the card plate drives the test tube rack carrier to make a linear motion.

[0022] Preferably, in the automatic blood sample injection processing device, the test tube rack has a plurality of test tube holes, and the plurality of test tube holes are arranged in sequence along the moving direction of the test tube rack.

[0023] Preferably, in the automatic blood sample injection processing device, the support plate is L-shaped, and the support plate includes a first straight portion and a second straight portion, the first straight portion is perpendicular to the moving direction of the test tube rack, the test tube rubber sleeve is arranged below the first straight portion and is rotatably connected to the first straight portion, and the second straight portion is placed on the mixing component mounting seat.

[0024] Preferably, in the automatic blood sample injection processing device, the mixing component further comprises:

[0025] A mixing bearing, which is arranged on the first straight portion;

[0026] A shaft rod, which is arranged in the shaft hole of the mixing bearing and passes through the shaft hole of the mixing bearing, the upper end of the shaft rod passes through the first straight portion, and the lower end of the shaft rod is fixedly connected to the test tube rubber sleeve;

[0027] A mixing motor, which is arranged at a corner of the support plate;

[0028] A second driving pulley connected to the output end of the mixing motor;

[0029] A second driven pulley, which is fixedly connected to the upper end of the shaft;

[0030] A second driving belt is disposed on the second driving pulley and the second driven pulley.

[0031] Preferably, in the automatic blood sample injection processing device, the guide structure includes a linear bearing and a sliding rod, the linear bearing is vertically arranged in the mixing component mounting seat, the sliding rod is vertically arranged in the linear bearing, and the top of the sliding rod is fixedly connected to the second straight portion.

[0032] Preferably, in the blood sample automatic sampling processing device, the moving component further comprises:

[0033] Mix the base;

[0034] A mixing guide rail, which is arranged on the mixing base along the vertical direction;

[0035] A mixing slider, which is slidably arranged on the mixing guide rail, and a mixing component mounting seat is fixed on the mixing slider;

[0036] The screw rod is vertically arranged, and the bottom of the screw rod rotates under the driving force of power. The upper end of the screw rod is fixedly connected to the mixing component mounting seat through a transmission nut, and passes through the mixing component mounting seat and the second straight portion, and can rotate relative to the mixing component mounting seat and the second straight portion.

[0037] Preferably, in the blood sample automatic sampling processing device, the mixing base is L-shaped and includes a horizontal portion and a vertical portion, the vertical portion is arranged between the test tube rack carrier and the second straight portion, the mixing guide rail is arranged on the vertical portion, the lower end of the screw rod passes through the horizontal portion, and the moving assembly further includes:

[0038] A ball bearing, the outer ring of which is fixed to the lower part of the vertical part and / or the top of the horizontal part of the mixing base, and the lower end of the screw is fixed to the inner ring of the ball bearing;

[0039] A height control motor is disposed on the top of the horizontal portion of the mixing base;

[0040] A third driving pulley connected to an output end of the height control motor;

[0041] a third driven pulley, which is rotatably disposed at the bottom of the horizontal portion and fixedly connected to the lower end of the screw rod;

[0042] A third driving belt is arranged on the third driving pulley and the third driven pulley.

[0043] Preferably, in the blood sample automatic sampling processing device, a test tube rack sensing window is provided on the test tube rack carrier, and the test tube rack sensing window is opposite to the test tube rack; hollow detection windows are respectively provided at positions opposite to each test tube hole on both sides of the test tube rack, and the height of the hollow detection window is higher than the height of the test tube rack carrier;

[0044] The blood sample automatic sampling processing device also includes:

[0045] A mounting bracket, which is arranged upstream of the mixing component, and includes a door-shaped structure bracket and a side bracket. The test tube rack carrier can pass through the door-shaped structure bracket under the drive of the driving motor. The side bracket is located on one side of the test tube rack carrier, and a code scanning slot is provided on the side bracket;

[0046] A test tube barcode scanner is fixed on the side bracket and is opposite to the barcode scanning slot. When any test tube is opposite to the barcode scanning slot, the test tube barcode scanner can only scan the barcode on the test tube opposite to the barcode scanning slot through the barcode scanning slot. The test tube barcode scanner, the barcode scanning slot and the test tube rubber sleeve are distributed on the same vertical plane.

[0047] A test tube detection assembly comprising:

[0048] A first detection unit, comprising a first reflective sensor, a second reflective sensor, a third reflective sensor and a first photoelectric transmitter, which are sequentially arranged on one side of the door-shaped structure support from top to bottom, wherein the setting height of the first reflective sensor is consistent with the position of the test tube cap at the top of the long test tube placed in the test tube hole, the setting height of the second reflective sensor is consistent with the position of the test tube cap at the top of the short test tube placed in the test tube hole, the setting height of the third reflective sensor is consistent with the height of the middle part of the bullet-shaped test tube placed in the test tube hole, and the height is within the range of the hollow detection window, and the first photoelectric transmitter is close to the third reflective sensor, and the height is within the range of the hollow detection window;

[0049] The second detection unit includes a first photoelectric receiver and a fourth reflective sensor arranged on the other side of the door-shaped structure support, the first photoelectric receiver is opposite to the first photoelectric transmitter, and the fourth reflective sensor can be opposite to the test tube rack sensing window during the movement of the test tube rack.

[0050] The utility model at least has the following beneficial effects:

[0051] The automatic blood sample injection processing device provided by the utility model integrates test tube detection and identification, test tube barcode scanning sample ID automatic entry and sample mixing, and has a high degree of automation, making the instrument operation easier and the overall test efficiency higher. The automatic blood sample injection processing device provided by the utility model has a simple and compact structure, and is not only small in size, but also saves installation space and is conducive to instrument miniaturization, and can also reduce costs.

[0052] Other advantages, objectives and features of the present invention will be embodied in part through the following description, and in part will be understood by those skilled in the art through research and practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0053] Figure 1 It is a structural schematic diagram of a blood sample automatic sampling processing device according to an embodiment of the utility model;

[0054] Figure 2 It is a structural schematic diagram of the automatic blood sample injection processing device according to one embodiment of the utility model from another angle;

[0055] Figure 3 It is a structural schematic diagram of the automatic blood sample injection processing device according to one embodiment of the utility model from another angle;

[0056] Figure 4 is a schematic structural diagram of a sample mixing mechanism according to an embodiment of the utility model;

[0057] Figure 5It is a schematic diagram of the structure of a test tube detection assembly for detecting and identifying a long test tube according to an embodiment of the utility model;

[0058] Figure 6 This is a schematic diagram of the structure of a test tube detection component for detecting and identifying a short test tube according to an embodiment of the utility model;

[0059] Figure 7 It is a schematic diagram of the structure of a test tube detection component for detecting and identifying a bullet-shaped test tube according to an embodiment of the utility model;

[0060] Figure 8 It is a flowchart of the test tube detection and identification method of the utility model;

[0061] Fig. 9 It is a flowchart of the utility model for judging whether there is a test tube in the detected test tube hole;

[0062] Fig.10 It is a flowchart of test tube type identification of the utility model;

[0063] Fig.11 It is a flow chart of the sample mixing control method of the utility model. DETAILED DESCRIPTION

[0064] The present invention will be further described in detail below in conjunction with the accompanying drawings so that those skilled in the art can implement the invention with reference to the description.

[0065] It should be noted that, in the description of the present invention, the terms "lateral", "longitudinal", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0066] like Figures 1 to 11 As shown, the utility model provides an automatic blood sample injection processing device, the blood sample is contained in a test tube, the test tube is inserted into a test tube hole of a test tube rack, and the test tube rack performs linear motion under the driving of a power, including:

[0067] A sample mixing mechanism, comprising:

[0068] A mixing component, comprising:

[0069] Support plate;

[0070] The test tube rubber sleeve is arranged below the support plate and is rotatably connected to the support plate. The test tube rubber sleeve rotates under the driving force of power, and the test tube rack can be moved to the bottom of the test tube rubber sleeve under the driving force of power. The contact surface between the test tube rubber sleeve and the test tube is provided with an exhaust groove 5161 to prevent negative pressure from being generated when the test tube is mixed. When the test tube rubber sleeve rises, the test tube is lifted.

[0071] A mobile assembly comprising:

[0072] The mixing component mounting seat, the support plate is placed on the mixing component mounting seat, but not fixed together, a vertical guide structure is provided between the mixing component mounting seat and the support plate, and the mixing component mounting seat moves up and down under the driving force. Under normal circumstances, the support plate is lifted up and down together with the mixing component mounting seat, and when the test tube rubber sleeve contacts the test tube, the support plate is lifted up by the test tube and separated from the top of the mixing component mounting seat, thereby playing a buffering role. During the lifting process, the guide structure plays a guiding role, so that the support plate can only move vertically relative to the mixing component mounting seat.

[0073] The automatic blood sample injection and processing device provided by the present solution, when in use, is powered to drive the test tube rack to make linear motion. When a test tube moves to the bottom of the test tube rubber cover, the mixing component mounting seat moves downward under the power drive, and the support plate erected on the mixing component mounting seat also moves downward. When the test tube rubber cover contacts the test tube, the support plate is lifted up by the test tube and detached from the top of the mixing component mounting seat, thereby playing a buffering role. The power then drives the test tube rubber cover to rotate to mix the sample. Finally, the mixing component mounting seat is driven upward by the power, and moves upward against the support plate, thereby moving the test tube rubber cover upward. The power drives the test tube rack to continue to move forward, and then repeats continuously.

[0074] In another embodiment, the blood sample automatic sampling and processing device further comprises:

[0075] A sample injection assembly comprising:

[0076] a test tube rack carrier, into which the test tube rack is inserted;

[0077] An injection guide rail, which is arranged on a fixed base (not shown);

[0078] An injection slide block is slidably arranged on the injection guide rail, and a test tube rack carrier is fixed on the injection slide block; a driving motor is arranged at one end of a fixed base;

[0079] A first driving pulley connected to an output end of the driving motor;

[0080] a first driven pulley rotatably disposed at the other end of the fixed base;

[0081] A first driving belt, which is arranged on the first driving pulley and the first driven pulley;

[0082] The card plate has one end stuck on the first driving belt and the other end connected to the side wall of the test tube rack carrier; when the driving motor drives the first active pulley to rotate, the first driving belt can drive the card plate to move linearly, and then the card plate drives the test tube rack carrier to move linearly. The belt card is a small card, one end of which is stuck on the belt and the other end is fixed to the test tube rack carrier by screws, which plays the role of connecting the first driving belt and the test tube rack carrier, so that the test tube carrier follows the belt movement.

[0083] The driving motor drives the first active pulley to rotate, thereby causing the test tube rack carrier to perform linear motion.

[0084] In another embodiment, in the automatic blood sample injection processing device, the test tube rack has a plurality of test tube holes, and the plurality of test tube holes are arranged in sequence along the movement direction of the test tube rack.

[0085] In another embodiment, in the automatic blood sample injection processing device, the support plate is L-shaped, that is, an L-shaped bracket, and the support plate includes a first straight portion and a second straight portion, the first straight portion is perpendicular to the moving direction of the test tube rack, the test tube rubber sleeve is arranged below the first straight portion and is rotatably connected to the first straight portion, and the second straight portion is placed on the mixing component mounting seat.

[0086] In another embodiment, in the blood sample automatic sampling processing device, the mixing component further comprises:

[0087] A mixing bearing, which is arranged on the first straight portion;

[0088] A shaft rod, which is arranged in the shaft hole of the mixing bearing and passes through the shaft hole of the mixing bearing, the upper end of the shaft rod passes through the first straight portion, and the lower end of the shaft rod is fixedly connected to the test tube rubber sleeve;

[0089] A mixing motor, which is arranged at a corner of the support plate;

[0090] A second driving pulley connected to the output end of the mixing motor;

[0091] A second driven pulley, which is fixedly connected to the upper end of the shaft;

[0092] A second driving belt is disposed on the second driving pulley and the second driven pulley.

[0093] The mixing motor drives the second active belt pulley to rotate, and then the second driven belt pulley drives the shaft rod and the test tube rubber sleeve to rotate.

[0094] In another embodiment, in the automatic blood sample injection and processing device, the guide structure includes a linear bearing and a sliding rod, the linear bearing is vertically arranged in the mixing component mounting seat, the sliding rod is vertically arranged in the linear bearing, and the top of the sliding rod is fixedly connected to the second straight portion.

[0095] The function of the linear bearing is to allow the slide rod to slide freely up and down in the direction of the linear bearing. The L-shaped bracket is fixedly installed on the upper end of the slide rod by screws, and the linear bearing is fixedly installed on the mixing component mounting seat. The mixing component mounting seat is driven by power to rise and fall. Under normal circumstances, the L-shaped bracket is lifted up and lifted up by the mixing component mounting seat. When the test tube rubber sleeve contacts the test tube, the L-shaped bracket is lifted up by the test tube and separated from the top of the mixing component mounting seat, thereby playing a buffering role. During the lifting process, the slide rod moves upward relative to the mixing component mounting seat.

[0096] In another embodiment, in the blood sample automatic sampling processing device, the moving component further comprises:

[0097] Mix the base;

[0098] A mixing guide rail, which is arranged on the mixing base along the vertical direction;

[0099] A mixing slider, which is slidably arranged on the mixing guide rail, and a mixing component mounting seat is fixed on the mixing slider;

[0100] The screw rod is vertically arranged, and the bottom of the screw rod rotates under the driving force of power. The upper end of the screw rod is fixedly connected to the mixing component mounting seat through a transmission nut, and passes through the mixing component mounting seat and the second straight portion, and can rotate relative to the mixing component mounting seat and the second straight portion.

[0101] The power drives the lead screw to rotate, thereby causing the mixing component mounting seat to move up and down.

[0102] In another embodiment, in the blood sample automatic sampling processing device, the mixing base is L-shaped and includes a horizontal portion and a vertical portion, the vertical portion is arranged between the test tube rack carrier and the second straight portion, the mixing guide rail is arranged on the vertical portion, the lower end of the screw rod passes through the horizontal portion, and the moving assembly further includes:

[0103] A ball bearing, the outer ring of which is fixed to the lower part of the vertical part and / or the top of the horizontal part of the mixing base, and the lower end of the screw is fixed to the inner ring of the ball bearing;

[0104] A height control motor is disposed on the top of the horizontal portion of the mixing base;

[0105] A third driving pulley connected to an output end of the height control motor;

[0106] a third driven pulley, which is rotatably disposed at the bottom of the horizontal portion and fixedly connected to the lower end of the screw rod;

[0107] A third driving belt is arranged on the third driving pulley and the third driven pulley.

[0108] The height control motor drives the third active pulley to rotate, thereby rotating the lead screw.

[0109] In another embodiment, in the blood sample automatic sampling and processing device, a test tube rack sensing window is provided on the test tube rack carrier, and the test tube rack sensing window is opposite to the test tube rack, so that the light emitted by the fourth reflective sensor is irradiated to the test tube rack through the test tube rack sensing window and then reflected back to the fourth reflective sensor for reception, and the amount of light reflected back is used to determine whether there is a test tube rack in the test tube rack carrier. In actual use, during the movement of the test tube rack, the test tube rack sensing window can be made to pass through the door-shaped structure bracket first, so that the presence of a test tube rack can be detected first, and then the presence of a test tube and the type of the test tube can be detected; hollow detection windows are respectively provided on both sides of the test tube rack at positions opposite to each test tube hole, and the height of the hollow detection window is higher than the height of the test tube rack carrier; a barcode is attached to the test tube, and the barcode on the test tube does not affect the detection of the first detection unit and the second detection unit;

[0110] The blood sample automatic sampling processing device also includes:

[0111] A mounting bracket is arranged upstream of the mixing component, that is, the test tube first passes through the mounting bracket and then moves toward the mixing component. The mounting bracket includes a door-shaped structure bracket and a side bracket. The test tube rack carrier can pass through the door-shaped structure bracket under the drive of the driving motor. The side bracket is located on one side of the test tube rack carrier, and a code scanning slot is provided on the side bracket;

[0112] The test tube barcode scanner is fixed on the side bracket and is opposite to the barcode scanning slot. When any test tube is opposite to the barcode scanning slot, the test tube barcode scanner can only scan the barcode on the test tube opposite to the barcode scanning slot through the barcode scanning slot (so that there is only one barcode image on the image taken by the barcode scanner to avoid two barcodes appearing in the taken image and causing misidentification). The test tube barcode scanner, the barcode scanning slot and the test tube rubber sleeve are distributed on the same vertical plane, so that the test tube rubber sleeve can be used to rotate the test tube while scanning the test tube barcode; the test tube barcode scanner shoots the sample barcode attached to the test tube through the barcode scanning slot opened on the mounting bracket to realize the automatic entry of sample ID information, and uses the blocking of the barcode scanning slot to prevent the barcode of the adjacent test tube from being mistakenly shot and identified.

[0113] A test tube detection assembly comprising:

[0114] A first detection unit, comprising a first reflective sensor, a second reflective sensor, a third reflective sensor and a first photoelectric transmitter, which are sequentially arranged on one side of the door-shaped structure support from top to bottom, wherein the setting height of the first reflective sensor is consistent with the position of the test tube cap at the top of the long test tube placed in the test tube hole, the setting height of the second reflective sensor is consistent with the position of the test tube cap at the top of the short test tube placed in the test tube hole, the setting height of the third reflective sensor is consistent with the height of the middle part of the bullet-shaped test tube placed in the test tube hole, and the height is within the range of the hollow detection window, and the first photoelectric transmitter is close to the third reflective sensor, and the height is within the range of the hollow detection window;

[0115] The second detection unit includes a first photoelectric receiver and a fourth reflective sensor arranged on the other side of the door-shaped structure support, the first photoelectric receiver is opposite to the first photoelectric transmitter, and the fourth reflective sensor can be opposite to the test tube rack sensing window during the movement of the test tube rack.

[0116] Before the instrument injects the sample, the uncapped sample tube is placed in the test tube hole 41 of the test tube rack 40, and the test tube rack is inserted into the test tube rack carrier 11. After the test tube rack is detected to be in place by the fourth reflective sensor 322, feedback is given to the control system. The control system controls the injection drive motor 15 to move the test tube rack carrier to the test tube detection position, and sequentially detects the status and type information of the test tubes in all the test tube holes and feeds back to the control system for record and preservation. The control system selects the test tube holes with long test tubes or short test tubes according to the status and type information of the test tubes in the test tube holes, and scans the test tube barcode of the test tube in the test tube hole, obtains the sample ID information and feeds it back to the control system. The control system displays the test tube status information and the corresponding sample ID information in the test tube hole in the UI interface, and provides it to the instrument user for sample application operation before testing.

[0117] Before each test sampling, the control system determines whether a long test tube or a short test tube is placed in the test tube hole for sampling based on the state and type information of the test tube in the test tube hole and the sample type is selected as a whole blood sample. Then, the control system mixes the sample in the test tube according to the sample mixing control method and then controls the pipetting mechanism to absorb the sample.

[0118] Reference Figure 7 , the test tube detection and identification method comprises the following steps:

[0119] S10: When the test tube is detected, when the amount of light received by the receiving holes of the reflective sensors in the first reflective sensor 311, the second reflective sensor 312, the third reflective sensor 313 and the fourth reflective sensor 322 exceeds the set threshold, they return a value of 1 respectively, otherwise they return a value of 0 respectively. When the test tube is detected, when the amount of light received by the first photoelectric receiver 321 exceeds the set threshold, it returns a value of 1, otherwise it returns a value of 0.

[0120] S20: judging whether there is a test tube in the detected test tube hole according to the return values ​​of the third reflective sensor 313 and the first photoelectric receiver 321.

[0121] S30: Further, the test tube type of the detected test tube is determined according to the values ​​returned by the first reflective sensor 311 and the second reflective sensor 312 .

[0122] S40: The return values ​​of the first reflective sensor 311, the second reflective sensor 312, the third reflective sensor 313 and the first photoelectric receiver 321 are combined into an identification code in order, and the returned identification code is compared with a preset identification code to determine the type of the detected test tube.

[0123] When there is a test tube containing non-dark liquid (such as serum or plasma) in the test tube hole being detected, the light emitted by the emitting hole of the third reflective sensor 313 passes through the hollow detection window 45 and illuminates the test tube wall. The amount of light reflected back to the receiving hole of the third reflective sensor 313 will exceed the set threshold value, and it returns a value of 1.

[0124] When there is a test tube containing dark liquid (such as whole blood) in the test tube hole to be detected, part of the light emitted by the emission hole of the third reflective sensor 313 is absorbed after passing through the hollow detection window 45, and the amount of light reflected back to the receiving hole of the third reflective sensor 313 is less than the set threshold value, and it returns to 0. At the same time, the light emitted by the first photoelectric transmitter 314 is blocked, and the amount of light received by the first photoelectric receiver 321 is less than the set threshold value, and it returns to 0.

[0125] When there is no test tube in the test tube hole to be detected, the light emitted by the emission hole of the third reflective sensor 313 passes through the hollow detection window 45 without being reflected by the test tube, and the light amount of the receiving hole of the third reflective sensor 313 is lower than the set threshold value, and it returns a value of 0. At the same time, after the light emitted by the first photoelectric transmitter 314 passes through the hollow detection window 45, the light amount received by the first photoelectric receiver 321 is greater than the set threshold value, and it returns a value of 1.

[0126] In summary, when the third reflective sensor 313 returns a value of 1, it can be determined that a test tube exists. When the third reflective sensor 313 returns a value of 0, it is necessary to combine the return value of the first photoelectric receiver 321 to determine whether a test tube exists.

[0127] Further, refer to Figure 8 In one example of the method, step S20: judging whether there is a test tube in the detected test tube hole according to the return value of the third reflective sensor 313 and the first photoelectric receiver 321, specifically includes the following steps:

[0128] S21: When the third reflective sensor 313 returns a value of 1, it is determined that a test tube exists in the detected test tube hole, and the return value of the first photoelectric receiver 321 can be ignored.

[0129] S22: When the third reflective sensor returns a value of 0 and the first photoelectric receiver 321 returns a value of 0, it is determined that a test tube exists in the detected test tube hole.

[0130] S23: When the third reflective sensor returns a value of 0 and the first photoelectric receiver 321 returns a value of 1, it is determined that there is no test tube in the detected test tube hole.

[0131] Further, after it is determined through the above step S20 that there is a test tube in the detected test tube hole, refer to Fig. 9 , through step S30: judging the test tube type of the detected test tube according to the values ​​returned by the first reflective sensor 311 and the second reflective sensor 312, specifically including the following steps:

[0132] S31: When the first reflective sensor 311 returns a value of 1, it is determined that the detected test tube is the long test tube 42. The return value of the second reflective sensor 312 can be ignored.

[0133] S32 : When the first reflective sensor 311 returns a value of 0 and the second reflective sensor 312 returns a value of 1, it is determined that the detected test tube is a short test tube 43 .

[0134] S33 : When the first reflective sensor 311 returns a value of 0 and the second reflective sensor 312 returns a value of 0, it is determined that the detected test tube is a bullet-shaped test tube 44 .

[0135] According to the above detection steps, and according to the order combination of the first reflective sensor 311, the second reflective sensor 312, the third reflective sensor 313, and the first photoelectric receiver 321, their possible return values ​​are preset as identification codes. The preset return value identification codes are shown in Table 1, wherein the “×” in the table indicates that the return value can be ignored.

[0136] Table 1 Preset return value identification code table

[0137]

[0138] Furthermore, before each test sampling, the control system of the analyzer determines whether the sampled test tube is a long test tube or a short test tube according to the state and type information of the test tube in the test tube hole and the sample type is selected as a whole blood sample, and then mixes the sample in the test tube according to the sample mixing control method, referring to Figure 8 , the sample mixing control method comprises the following steps:

[0139] S50: When the sample is mixed, the height control motor 531 is controlled to make the test tube rubber cover 516 descend to a height corresponding to the test tube to cover the test tube opening.

[0140] Specifically, after the sample injection drive motor 15 rotates, it drives the test tube rack carrier to carry the test tube rack to make a linear motion along the guide rail direction, and controls the drive motor to rotate to the preset sampling coordinates and mixing coordinates corresponding to each test tube hole. The origin of the coordinates is sensed by the origin sensor. In this way, the test tubes can be moved one by one to the bottom of the test tube rubber sleeve 516.

[0141] Specifically, a limit sensor is provided on the side of the mixing component mounting seat 524 away from the test tube rack or the injection guide rail, and the limit sensor can be an infrared grating blocking sensor. An L-shaped baffle 538 is provided at the bottom of the mixing component mounting seat 524. The L-shaped baffle 538 includes a horizontal first sheet and a vertical second sheet, so that the bottom of the slide rod is fixedly connected to the first sheet (so that the L-shaped baffle 538 and the slide rod and the L-shaped bracket form a whole), and the second sheet is on the same side as the side of the mixing component mounting seat 524 away from the test tube rack or the injection guide rail, and the screw rod passes through the first sheet and can rotate relative to the first sheet. When the L-shaped bracket is placed on the mixing component mounting seat 524, the L-shaped baffle 538 is located below the mixing component mounting seat 524 and is separated from the mixing component mounting seat 524 by a certain distance, so that the baffle can move upward relative to the mixing component mounting seat 524. When the test tube rubber sleeve 516 on the mixing component 51 contacts the test tube, the test tube will lift up the entire mixing component 51, and the baffle will also move upwards. Because the limit sensor is fixed on the mixing component mounting base 524, the limit sensor will not move upwards. The upward movement of the baffle will block the light path of the infrared light transmission, so that the test tube can be sensed to be lifted up. At this time, the controller controls the height control motor to stop rotating, and the mixing component 51 will no longer move downward. In this way, the test tube rubber sleeve 516 can be lowered to the height corresponding to the test tube to cover the test tube mouth, and even if the test tube height is different, the test tube mouth can be covered.

[0142] The rotating speed and rotating direction of the test tube are adjusted by controlling the mixing motor 511, and the rotation of the test tube is used to generate a vortex in the sample liquid in the test tube.

[0143] Furthermore, the steps of making the sample liquid in the test tube generate a sufficient vortex are as follows:

[0144] S61: Control the mixing motor to rotate continuously for several circles at a certain speed in the same direction and then stop. Wait for a while to allow the liquid in the test tube to stir by itself due to inertia. The vortex formed causes the material at the bottom to float upward layer by layer.

[0145] S62: Continue to control the mixing motor to perform the next round of rotation according to the steps described in S61.

[0146] S63: Rotate in the same direction for multiple rounds according to the steps in S61 until convection is formed between the liquid layers due to the influence of eddy currents.

[0147] When the liquid is completely suspended, the control method of repeated forward and reverse rotation is adopted to make the liquid layer form turbulence to further mix the substances in the liquid layer, thereby achieving the effect of multi-dimensional full mixing.

[0148] Furthermore, the steps of making the sample liquid in the test tube form turbulence and fully mix are as follows:

[0149] S71: Control the mixing motor to rotate continuously in the positive direction at a certain speed for several circles and then stop, wait for a while, and let the liquid in the test tube be stirred in the positive direction due to inertia.

[0150] S72: Control the mixing motor to rotate continuously in the reverse direction at a certain speed for several circles and then stop, wait for a while, and let the liquid in the test tube be stirred in the reverse direction due to inertia.

[0151] S73: Continue to repeat steps S71 and S72 until the liquid in the tube is fully mixed by repeated forward and reverse rotation.

[0152] Compared with the existing test tube detection technology, the test tube detection component adopts a detection method combining reflection detection and transmission detection based on the principle of photoelectric detection to detect the test tube and identify the type of the test tube through the detection and identification method. This solves the problem that only one of the detection methods can detect the presence or absence of test tubes of the same type and cannot identify and distinguish the types of test tubes.

[0153] When the analyzer is loading samples, the control system will detect the status and type information of all test tubes in the test tube wells in turn and record and save them. Based on the status and type information of the test tubes in the test tube wells, the control system selects the test tube wells with long test tubes and short test tubes, scans the test tube barcodes of the test tubes in the test tube wells to obtain the sample ID information, and displays the test tube status information and corresponding sample ID information in the test tube wells in the UI interface, which is provided to the instrument user for sample application operations before testing.

[0154] Before each test sampling, the control system of the analyzer determines whether the test tube placed in the test tube hole for sampling is a long test tube or a short test tube according to the state and type information of the test tube in the test tube hole and the sample type is selected as a whole blood sample, and then performs a mixing operation on the sample in the test tube according to the sample mixing control method, and the sample mixing control method includes the following steps:

[0155] When mixing the sample, the height control motor is controlled to make the test tube rubber sleeve drop to the height corresponding to the test tube and cover the test tube mouth, and the friction between the test tube rubber sleeve and the test tube mouth is used to drive the test tube to rotate synchronously with the test tube rubber sleeve. The rotation speed and rotation direction of the test tube are adjusted by controlling the mixing motor, and the rotation of the test tube is used to make the sample liquid in the test tube produce a vortex, and the convection effect formed by the vortex is used to fully mix the liquid. However, to achieve a perfect mixing effect, sufficient vortex is very important. Therefore, how to control the rotation of the test tube to produce sufficient vortex is more critical. The steps to produce sufficient vortex in the sample liquid in the test tube are as follows:

[0156] First, the mixing motor is controlled by a multi-round intermittent rotation control method. Each round controls the mixing motor to rotate at a certain speed in the same direction, and stops rotating after a certain number of turns, allowing the liquid in the test tube to stir by itself due to inertia. The vortex formed causes the bottom layer of material to float to the upper layer layer by layer. After waiting for a while, the mixing motor is controlled to rotate for the next round. After multiple rounds of rotation in the same direction, convection is formed between the liquid layers due to the vortex. The above intermittent rotation control steps can avoid the centrifugal effect caused by the long-term synchronous rotation of the test tube and the liquid, resulting in liquid overflow and the failure to achieve a sufficient mixing effect due to the attachment of some materials to the inner wall of the test tube due to the centrifugal force.

[0157] When the liquid suspension no longer shows obvious stratification, a control method of repeated positive and negative rotation is then used to make the liquid layer form turbulence to further mix the substances in the liquid layer, thereby achieving a multi-dimensional full mixing effect.

[0158] The sample mixing control method described in the utility model adopts a control method combining intermittent rotation control and repeated positive and negative rotation control, which is better than the control method that only adopts repeated positive and negative rotation. Because if the sample volume in the test tube is too much, turbulence can only be formed in a fixed liquid layer in the liquid, rather than a real vortex, so that no convection effect can be formed, and the liquids between the liquid layers cannot be mixed with each other, and the overall mixing effect will be greatly reduced.

[0159] The sampling component described in the utility model is used to realize automatic sampling of a test tube rack containing sample test tubes; the test tube barcode scanner is used to scan and identify the barcode information of the test tube to realize the function of automatically entering the sample ID information; the test tube detection component is used to detect and identify the situation of the test tube placed in the test tube rack and display the optional status of the test tube on the screen of the instrument through the UI interface, which can prevent the operator from mistakenly selecting the wrong sampling position for the test; the sample mixing mechanism can not only be used to vortex mix the sample in the test tube, but also can be used to rotate the test tube to change the barcode orientation when scanning and identifying the test tube barcode, so that the test tube barcode direction can be placed at will without being affected by scanning and identifying the test tube barcode, thereby improving the operation efficiency.

[0160] Compared with the visual detection principle using expensive cameras and complex image recognition algorithms, the test tube detection assembly of the utility model has a simple structure and lower cost. Compared with only one detection method in the photoelectric detection principle, the utility model adopts a detection method combining reflection detection and transmission detection, which can not only identify all types of test tubes, but also has higher reliability.

[0161] Compared with the sample mixing mechanism of medium and large chemiluminescence instruments, which uses shaking to mix the sample and then uses a puncture needle to take samples, the sample mixing mechanism described in the utility model adopts a liquid-free design, so the POCT single-portion chemiluminescence immunoassay can only use a disposable TIP for sampling. Before using the disposable TIP for sampling, the test tube must be uncapped. If the uncapped test tube is still shaken to mix the sample, it will cause sample splashing. The sample mixing mechanism described in the utility model adopts a vortex mixing method, which solves the disadvantage that the shaking mixing method cannot mix the sample of the uncapped test tube.

[0162] The automatic sampling processing device and its control system provided by the utility model integrate automatic sampling, test tube detection and identification, test tube barcode scanning sample ID automatic entry and sample mixing, and have a high degree of automation, making the instrument operation easier and making the overall test efficiency higher. The automatic sampling processing device provided by the utility model has a simple and compact structure, is not only small in size, can save installation space, is conducive to instrument miniaturization, but also can reduce costs.

[0163] like Figures 1 to 4 As shown, an automatic sample injection processing device includes a sample injection component 10, a mounting bracket 20, a test tube code scanner 60, a sample mixing mechanism 50 and a test tube detection component 30.

[0164] The injection assembly 10 includes a test tube rack carrier 11, an injection slider 13, an injection guide rail 14, an injection drive motor 15, a first active pulley 17, a first driven pulley 18 and a first driving belt 16. The output end of the injection drive motor 15 is provided with a first active pulley 17, the injection drive motor 15 and the injection guide rail 14 are both mounted on a base (not shown) of the instrument, and a first driven pulley 18 is provided on the base (not shown) opposite to the other end where the injection drive motor 15 is mounted, and the first active pulley 17 is connected to the first driven pulley 18 via the first driving belt 16;

[0165] The test tube rack carrier 11 is fixed on the sample injection slide 13 , and the sample injection slide 13 is assembled on the sample injection guide rail 14 . A belt clamp 19 for connecting and fixing the first driving belt 16 is provided on the side wall of the test tube rack carrier 11 .

[0166] The injection drive motor 15 drives the first drive belt 16 to move back and forth in a straight line through the first active pulley 17 and the first driven pulley 18. The first drive belt 16 that moves back and forth in a straight line passes through the belt clamp 19 to drive the test tube rack carrier 11 to slide on the injection guide rail 14. The test tube rack 40 inserted and placed on the test tube rack carrier 11 can be moved to corresponding working positions such as the test tube detection position, the sample mixing position and the sampling position by controlling the injection drive motor 15.

[0167] Among them, a sample mixing mechanism 50 and a test tube barcode scanner 60 are provided on one side of the mounting bracket 20. A door-shaped structure bracket 21 is provided on the other side of the mounting bracket 20. Test tube detection components 30 for test tube detection and identification are provided on both sides of the door-shaped structure bracket 21. The middle of the door-shaped structure bracket is a test tube feeding area for the test tube rack 40 to enter and exit. The mounting bracket 20 is fixed on the base of the instrument (not shown) and is located between the sample introduction component 10 and the test tube barcode scanner 60.

[0168] The test tube barcode scanner 60 captures the sample barcode attached to the test tube through the barcode scanning slot 22 provided on the mounting bracket 20 to realize the automatic entry of sample ID information, and uses the barcode scanning slot 22 to prevent the barcode of an adjacent test tube from being mistakenly captured and identified.

[0169] The sample mixing mechanism includes a mixing component 51 and a moving component 52. A mixing bearing 513 is provided at one end of an L-shaped bracket 510 of the mixing component 51. A shaft 514 passing through the shaft hole is provided in the shaft hole of the mixing bearing 513. A second driven pulley 515 is provided at the upper end of the shaft 514. A test tube rubber sleeve 516 is provided at the lower end of the shaft 514 to cover the mouth of the test tube so that the test tube rotates with the test tube rubber sleeve. A mixing motor 511 for mixing the test tube is provided at the corner of the L-shaped bracket 510. A second driving pulley 512 is provided at the output end of the mixing motor 511.

[0170] The second active pulley 512 is connected to the second driven pulley 515 through the second driving belt 517. The mixing motor 511 drives the second driven pulley 515 to rotate through the second active pulley 512 and the second driving belt 517. The second driven pulley 515 is connected to the test tube rubber sleeve 516 through the shaft 514. When the test tube rubber sleeve 516 covers the test tube, the test tube rotates with the test tube rubber sleeve 516. The mixing motor 511 is controlled to rotate repeatedly and continuously to drive the test tube to rotate, thereby driving the sample in the test tube to rotate to form a vortex to achieve mixing of the sample in the test tube.

[0171] A mixing guide rail 522 is provided on the mixing base 521 of the moving component 52 in the vertical direction, and a mixing slider 523 is installed on the mixing guide rail 522, and the mixing slider 523 is fixedly connected to the mixing component mounting seat 524. A linear bearing 525 is provided in the mixing component mounting seat 524 along the direction of the mixing guide rail 522, and a sliding rod 526 is provided in the linear bearing 525. The sliding rod 526 can slide freely up and down along the direction of the linear bearing 525. The upper end of the sliding rod 526 is fixedly connected to the L-shaped bracket 510 of the mixing component, so that the mixing component can move freely up and down along the direction of the linear bearing. The mixing component 51 fixed on the upper end of the sliding rod 526 will fall down and lean against the top of the mixing component mounting seat 524 due to gravity. When the mixing assembly mounting seat moves downward with the mixing assembly, when the test tube rubber sleeve 516 on the mixing assembly 51 contacts the test tube, the test tube will lift up the entire mixing assembly 51 to play a buffering role, thereby preventing the test tube rubber sleeve from covering the test tube too tightly and causing excessive friction at the bottom of the test tube to affect the smoothness of the test tube rotation.

[0172] The lower end of the mixing base 521 of the mobile assembly 52 is provided with a height control motor 531 and a ball bearing 532. A screw rod 533 is provided through the ball bearing 532 along the direction of the mixing guide rail 522. The screw rod 533 is fixedly assembled with the inner ring of the ball bearing 532, and the outer ring of the ball bearing 532 is fixed with the mixing base 521, so that the screw rod 533 is indirectly fixed on the mixing base 521 and can only rotate freely but cannot move up and down. The upper end of the screw rod 533 is fixedly connected to the mixing assembly mounting seat 524 through a transmission nut 534, and the lower end of the screw rod 533 is provided with a third driven pulley 535. The output end of the height control motor 531 is provided with a third active pulley 536, and the third active pulley 536 is connected to the third driven pulley 535 through a third driving belt 537. When the height control motor rotates with the screw rod 533 through the third driving belt 537, the transmission nut 534 drives the mixing assembly mounting seat 524 to move up and down along the direction of the screw rod 533.

[0173] In particular, the test tube barcode scanner 60, the barcode scanning slot 22 and the test tube rubber sleeve 516 should be distributed on a plane, so that the test tube rubber sleeve 516 can be used to rotate the test tube while scanning the test tube barcode, and the surface with the test tube barcode can be rotated toward the test tube barcode scanner 60, so that the test tube barcode can be photographed by the test tube barcode through the barcode scanning slot 22, so as to realize the automatic rotating test tube scanning function, which is far superior to the products without test tube rotation function on the market.

[0174] The test tube rack carrier 11 is used to place the inserted test tube rack 40. The inner end of the test tube rack carrier 11 is provided with a test tube rack sensing window 12. The test tube rack 40 is provided with a test tube hole 41 for placing the test tube. The test tube hole 41 can be used to place three types of test tubes, namely, a long test tube 42, a short test tube 43 and a bullet-shaped test tube 44. Hollow detection windows 45 are provided on both sides of the test tube hole 41 of the test tube rack 40, so that light can pass through the hollow detection window 45 and pass through the test tube rack 40;

[0175] Among them, Figures 5 to 7 As shown, the test tube detection assembly includes a first detection unit 31 and a second detection unit 32, and the first detection unit 31 and the second detection unit 32 are respectively arranged on both sides of the door-shaped structure of the mounting bracket 20. The first detection unit 31 is composed of a first reflective sensor 311, a second reflective sensor 312, a third reflective sensor 313 and a first photoelectric transmitter 314. The second detection unit is composed of a first photoelectric receiver 321 and a fourth reflective sensor 322.

[0176] Among them, the first reflective sensor 311, the second reflective sensor 312, the third reflective sensor 313 and the first photoelectric emitter 314 in the first detection unit 31 are arranged vertically, and the arrangement order from high to low is the first reflective sensor 311, then the second reflective sensor 312, then the third reflective sensor 313, and finally the first photoelectric emitter 314.

[0177] Furthermore, the height at which the first reflective sensor 311 is set should be consistent with the height of the test tube cap position 46 at the top of the long test tube 42 placed in the test tube hole 41, the height at which the second reflective sensor 312 is set should be consistent with the height of the test tube cap position 46 at the top of the short test tube 43 placed in the test tube hole 41, the height at which the third reflective sensor 313 is set should be consistent with the middle height of the bullet-shaped test tube 44 placed in the test tube hole 41 and the height should be within the range of the hollow detection window 45, and the first photoelectric emitter 314 should be set directly below the third reflective sensor 313 and the height should be within the range of the hollow detection window 45.

[0178] The first photoelectric receiver 321 in the second detection unit 32 is arranged opposite to the first photoelectric transmitter 314 in the first detection unit 31. The fourth reflective sensor 322 in the second detection unit 32 is arranged at the same height as the test tube rack sensing window 12 in the test tube rack carrier 11, so that the light emitted by the fourth reflective sensor 322 is irradiated to the test tube rack 40 through the test tube rack sensing window 12 and then reflected back to the fourth reflective sensor 322 for reception, and the presence or absence of the test tube rack 40 in the test tube rack carrier 11 is determined by judging the amount of the reflected light.

[0179] Further, after the test tube rack 40 is inserted into the test tube rack carrier 11 and abutted against the inner end, the fourth reflective sensor 322 detects that the test tube rack is in place, and then the sample injection assembly 10 drives the test tube rack carrier 11 to move at the spacing between the test tube holes 41, and sequentially detects the status and type of the test tubes in all the test tube holes 41. The test tube status is present or absent, and the test tube types are long test tubes 42, short test tubes 43, and bullet-shaped test tubes 44. All test tubes have their test tube caps 46 removed before the injection test.

[0180] Furthermore, the utility model also proposes a control system applied to an automatic sample injection processing device. The control system includes a method for realizing test tube detection and identification and a method for sample mixing control.

[0181] Reference Figure 7 , the test tube detection and identification method comprises the following steps:

[0182] S10: When the test tube is detected, when the amount of light received by the receiving holes of the reflective sensors in the first reflective sensor 311, the second reflective sensor 312, the third reflective sensor 313 and the fourth reflective sensor 322 exceeds the set threshold, they return a value of 1 respectively, otherwise they return a value of 0 respectively. When the test tube is detected, when the amount of light received by the first photoelectric receiver 321 exceeds the set threshold, it returns a value of 1, otherwise it returns a value of 0.

[0183] S20: judging whether there is a test tube in the detected test tube hole according to the return values ​​of the third reflective sensor 313 and the first photoelectric receiver 321.

[0184] S30: Further, the test tube type of the detected test tube is determined according to the values ​​returned by the first reflective sensor 311 and the second reflective sensor 312 .

[0185] S40: The return values ​​of the first reflective sensor 311, the second reflective sensor 312, the third reflective sensor 313 and the first photoelectric receiver 321 are combined into an identification code in order, and the returned identification code is compared with a preset identification code to determine the type of the detected test tube.

[0186] When there is a test tube containing non-dark liquid (such as serum or plasma) in the test tube hole being detected, the light emitted by the emitting hole of the third reflective sensor 313 passes through the hollow detection window 45 and illuminates the test tube wall. The amount of light reflected back to the receiving hole of the third reflective sensor 313 will exceed the set threshold value, and it returns a value of 1.

[0187] When there is a test tube containing dark liquid (such as whole blood) in the test tube hole to be detected, part of the light emitted by the emission hole of the third reflective sensor 313 is absorbed after passing through the hollow detection window 45, and the amount of light reflected back to the receiving hole of the third reflective sensor 313 is less than the set threshold value, and it returns to 0. At the same time, the light emitted by the first photoelectric transmitter 314 is blocked, and the amount of light received by the first photoelectric receiver 321 is less than the set threshold value, and it returns to 0.

[0188] When there is no test tube in the test tube hole to be detected, the light emitted by the emission hole of the third reflective sensor 313 passes through the hollow detection window 45 without being reflected by the test tube, and the light amount of the receiving hole of the third reflective sensor 313 is lower than the set threshold value, and it returns a value of 0. At the same time, after the light emitted by the first photoelectric transmitter 314 passes through the hollow detection window 45, the light amount received by the first photoelectric receiver 321 is greater than the set threshold value, and it returns a value of 1.

[0189] In summary, when the third reflective sensor 313 returns a value of 1, it can be determined that a test tube exists. When the third reflective sensor 313 returns a value of 0, it is necessary to combine the return value of the first photoelectric receiver 321 to determine whether a test tube exists.

[0190] Further, refer to Figure 8 In one example of the method, step S20: judging whether there is a test tube in the detected test tube hole according to the return value of the third reflective sensor 313 and the first photoelectric receiver 321, specifically includes the following steps:

[0191] S21: When the third reflective sensor 313 returns a value of 1, it is determined that a test tube exists in the detected test tube hole, and the return value of the first photoelectric receiver 321 can be ignored.

[0192] S22: When the third reflective sensor returns a value of 0 and the first photoelectric receiver 321 returns a value of 0, it is determined that a test tube exists in the detected test tube hole.

[0193] S23: When the third reflective sensor returns a value of 0 and the first photoelectric receiver 321 returns a value of 1, it is determined that there is no test tube in the detected test tube hole.

[0194] Further, after it is determined through the above step S20 that there is a test tube in the detected test tube hole, refer to Fig. 9 , through step S30: judging the test tube type of the detected test tube according to the values ​​returned by the first reflective sensor 311 and the second reflective sensor 312, specifically including the following steps:

[0195] S31: When the first reflective sensor 311 returns a value of 1, it is determined that the detected test tube is the long test tube 42. The return value of the second reflective sensor 312 can be ignored.

[0196] S32 : When the first reflective sensor 311 returns a value of 0 and the second reflective sensor 312 returns a value of 1, it is determined that the detected test tube is a short test tube 43 .

[0197] S33 : When the first reflective sensor 311 returns a value of 0 and the second reflective sensor 312 returns a value of 0, it is determined that the detected test tube is a bullet-shaped test tube 44 .

[0198] Furthermore, before each test sampling, the control system of the analyzer determines the position of the test tube in the test tube hole.

[0199] Status and type information, if the sample tube hole is a long tube or a short tube and the sample type is a whole blood sample, the sample in the tube is mixed according to the sample mixing control method, refer to Figure 8, the sample mixing control method comprises the following steps:

[0200] S50: When the sample is mixed, the height control motor 531 is controlled to make the test tube rubber cover 516 descend to a height corresponding to the test tube to cover the test tube opening.

[0201] The rotating speed and rotating direction of the test tube are adjusted by controlling the mixing motor 511, and the rotation of the test tube is used to generate a vortex in the sample liquid in the test tube.

[0202] Furthermore, the steps of making the sample liquid in the test tube generate a sufficient vortex are as follows:

[0203] S61: Control the mixing motor to rotate continuously for several circles at a certain speed in the same direction and then stop. Wait for a while to allow the liquid in the test tube to stir by itself due to inertia. The vortex formed causes the material at the bottom to float upward layer by layer.

[0204] S62: Continue to control the mixing motor to perform the next round of rotation according to the steps described in S61.

[0205] S63: Rotate in the same direction for multiple rounds according to the steps in S61 until convection is formed between the liquid layers due to the influence of eddy currents.

[0206] When the liquid is completely suspended, the control method of repeated forward and reverse rotation is adopted to make the liquid layer form turbulence to further mix the substances in the liquid layer, thereby achieving the effect of multi-dimensional full mixing.

[0207] Furthermore, the steps of making the sample liquid in the test tube form turbulence and fully mix are as follows:

[0208] S71: Control the mixing motor to rotate continuously in the positive direction at a certain speed for several circles and then stop, wait for a while, and let the liquid in the test tube be stirred in the positive direction due to inertia.

[0209] S72: Control the mixing motor to rotate continuously in the reverse direction at a certain speed for several circles and then stop, wait for a while, and let the liquid in the test tube be stirred in the reverse direction due to inertia.

[0210] S73: Continue to repeat steps S71 and S72 until the liquid in the tube is fully mixed by repeated forward and reverse rotation.

[0211] Although the implementation scheme of the utility model has been disclosed as above, it is not limited to the applications listed in the specification and implementation modes. It can be fully applied to various fields suitable for the utility model. For those familiar with the art, additional modifications can be easily implemented. Therefore, without departing from the general concept defined by the claims and the scope of equivalents, the utility model is not limited to the specific details and the illustrations shown and described herein.

Claims

1. A blood sample automatic sampling and processing device, wherein the blood sample is contained in a test tube, the test tube is inserted into a test tube hole of a test tube rack, and the test tube rack moves linearly under the driving force, characterized in that: include: A sample mixing mechanism, comprising: A mixing component, comprising: Support plate; The test tube rubber sleeve is arranged below the support plate and is rotatably connected to the support plate. The test tube rubber sleeve rotates under the driving force, and the test tube rack can move to the position directly below the test tube rubber sleeve under the driving force; A mobile assembly comprising: A mixing component mounting seat, the support plate is placed on the mixing component mounting seat, a vertical guide structure is arranged between the mixing component mounting seat and the support plate, and the mixing component mounting seat moves up and down under the driving force.

2. The blood sample automatic sampling processing device according to claim 1, characterized in that: Also includes: A sample injection assembly comprising: a test tube rack carrier, into which the test tube rack is inserted; An injection guide rail, which is arranged on a fixed base; An injection slide block is slidably disposed on the injection guide rail, and a test tube rack carrier is fixed on the injection slide block; A driving motor is arranged at one end of the fixed base; A first driving pulley connected to an output end of the driving motor; a first driven pulley rotatably disposed at the other end of the fixed base; A first driving belt, which is arranged on the first driving pulley and the first driven pulley; The card plate has one end clamped on the first driving belt and the other end connected to the side wall of the test tube rack carrier; when the driving motor drives the first active pulley to rotate, the first driving belt can drive the card plate to make a linear motion, and then the card plate drives the test tube rack carrier to make a linear motion.

3. The blood sample automatic sampling processing device according to claim 2, characterized in that: The test tube rack has a plurality of test tube holes, and the plurality of test tube holes are arranged in sequence along the moving direction of the test tube rack.

4. The blood sample automatic sampling processing device according to claim 3, characterized in that: The support plate is L-shaped and includes a first straight portion and a second straight portion. The first straight portion is perpendicular to the moving direction of the test tube rack. The test tube rubber sleeve is arranged below the first straight portion and is rotatably connected to the first straight portion. The second straight portion is placed on the mixing component mounting seat.

5. The blood sample automatic sampling processing device according to claim 4, characterized in that: The mixing component also includes: A mixing bearing, which is arranged on the first straight portion; A shaft rod, which is arranged in the shaft hole of the mixing bearing and passes through the shaft hole of the mixing bearing, the upper end of the shaft rod passes through the first straight portion, and the lower end of the shaft rod is fixedly connected to the test tube rubber sleeve; A mixing motor, which is arranged at a corner of the support plate; A second driving pulley connected to the output end of the mixing motor; A second driven pulley, which is fixedly connected to the upper end of the shaft; A second driving belt is disposed on the second driving pulley and the second driven pulley.

6. The blood sample automatic sampling processing device according to claim 4, characterized in that: The guide structure includes a linear bearing and a sliding rod. The linear bearing is arranged in the mixing component mounting seat along the vertical direction. The sliding rod is vertically arranged in the linear bearing. The top of the sliding rod is fixedly connected to the second straight portion.

7. The blood sample automatic sampling processing device according to claim 4, characterized in that: The mobile component also includes: Mix the base; A mixing guide rail, which is arranged on the mixing base along the vertical direction; A mixing slider, which is slidably arranged on the mixing guide rail, and a mixing component mounting seat is fixed on the mixing slider; The screw rod is vertically arranged, and the bottom of the screw rod rotates under the driving force of power. The upper end of the screw rod is fixedly connected to the mixing component mounting seat through a transmission nut, and passes through the mixing component mounting seat and the second straight portion, and can rotate relative to the mixing component mounting seat and the second straight portion.

8. The blood sample automatic sampling processing device according to claim 7, characterized in that: The mixing base is L-shaped and includes a horizontal portion and a vertical portion, the vertical portion is arranged between the test tube rack carrier and the second straight portion, the mixing guide rail is arranged on the vertical portion, the lower end of the screw rod passes through the horizontal portion, and the moving assembly further includes: A ball bearing, the outer ring of which is fixed to the lower part of the vertical part and / or the top of the horizontal part of the mixing base, and the lower end of the screw is fixed to the inner ring of the ball bearing; A height control motor is disposed on the top of the horizontal portion of the mixing base; A third driving pulley connected to an output end of the height control motor; a third driven pulley, which is rotatably disposed at the bottom of the horizontal portion and fixedly connected to the lower end of the screw rod; A third driving belt is arranged on the third driving pulley and the third driven pulley.

9. The blood sample automatic sampling processing device according to claim 3, characterized in that: The test tube rack carrier is provided with a test tube rack sensing window, and the test tube rack sensing window is opposite to the test tube rack; hollow detection windows are respectively provided at positions opposite to each test tube hole on both sides of the test tube rack, and the height of the hollow detection window is higher than the height of the test tube rack carrier; The blood sample automatic sampling processing device also includes: A mounting bracket, which is arranged upstream of the mixing component, and includes a door-shaped structure bracket and a side bracket. The test tube rack carrier can pass through the door-shaped structure bracket under the drive of the driving motor. The side bracket is located on one side of the test tube rack carrier, and a code scanning slot is provided on the side bracket; A test tube barcode scanner is fixed on the side bracket and is opposite to the barcode scanning slot. When any test tube is opposite to the barcode scanning slot, the test tube barcode scanner can only scan the barcode on the test tube opposite to the barcode scanning slot through the barcode scanning slot. The test tube barcode scanner, the barcode scanning slot and the test tube rubber sleeve are distributed on the same vertical plane. A test tube detection assembly comprising: A first detection unit, comprising a first reflective sensor, a second reflective sensor, a third reflective sensor and a first photoelectric transmitter, which are sequentially arranged on one side of the door-shaped structure support from top to bottom, wherein the setting height of the first reflective sensor is consistent with the position of the test tube cap at the top of the long test tube placed in the test tube hole, the setting height of the second reflective sensor is consistent with the position of the test tube cap at the top of the short test tube placed in the test tube hole, the setting height of the third reflective sensor is consistent with the height of the middle part of the bullet-shaped test tube placed in the test tube hole, and the height is within the range of the hollow detection window, and the first photoelectric transmitter is close to the third reflective sensor, and the height is within the range of the hollow detection window; The second detection unit includes a first photoelectric receiver and a fourth reflective sensor arranged on the other side of the door-shaped structure support, the first photoelectric receiver is opposite to the first photoelectric transmitter, and the fourth reflective sensor can be opposite to the test tube rack sensing window during the movement of the test tube rack.

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