Biochip packaging structure
By designing a biochip packaging structure including a protective case, frame and sealing plate, the problem of insufficient stability and reliability of biological wafers in the packaging structure is solved, multiple protection and temperature stability of biological wafers are achieved, and the stability and service life of biological chips are improved.
Patent Information
- Application Number
- CN202421999419.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-19
- Publication Date
- 2025-06-10
- Estimated Expiration
- 2034-08-19
AI Technical Summary
Bio-chips are susceptible to environmental conditions in the packaging structure, resulting in insufficient stability and reliability, and it is difficult to effectively protect their performance and service life.
A biological wafer packaging structure is designed, including protective shells, frames, sealing plates, limit slots, limit blocks, knobs and other components. Through technical means such as snapping mechanisms and heat-condensing pipes, multiple protection and temperature stability of biological wafers are achieved.
It effectively improves the stability, reliability and service life of biochips, prevents external physical and chemical damage, and ensures the accuracy of detection results and the purity of biological samples.
Smart Images

Figure CN222966126U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of packaging structures, in particular to a biological chip packaging structure. Background Art
[0002] Biological chips are high-tech components composed of substrates such as silicon wafers, glass, or polymers. They are fabricated using principles of molecular biology, genetic information, analytical chemistry, etc., through microelectromechanical automation or other precision machining techniques. As a product at the intersection of biotechnology and microelectronics, the bioactive molecules (such as DNA, RNA, proteins, etc.) on biological chips are very sensitive to environmental conditions (such as temperature, humidity, light, etc.). Biological chip packaging technology is a technology that integrates biological chips with other electronic components, sensors, etc. Through a tiny chip platform, biological chip technology can simultaneously detect and analyze multiple biological molecules, such as DNA, RNA, proteins, etc., providing a rapid, accurate, and high-throughput detection means for medical diagnosis. The packaging structure of biological chips ensures the stability and reliability of these biological molecules on the chips, thereby guaranteeing the accuracy of diagnostic results. For this reason, a biological chip packaging structure is proposed. Summary of the Utility Model
[0003] The utility model solves the technical problems in the above background art and provides a biological chip packaging structure.
[0004] The technical solution provided by the utility model to solve the above technical problems is as follows:
[0005] A biological chip packaging structure includes a protective shell. A frame is arranged inside the protective shell. A sealing plate is installed on the frame. A second limiting groove is arranged on the sealing plate. A limiting block is arranged in the second limiting groove. A limiting column is fixedly connected to the middle of the limiting block. A knob is installed on one side of the limiting column. A fixing block is installed on the side of the limiting column away from the knob. A spring is installed below the limiting block. The limiting column penetrates and is slidably connected to the sealing plate.
[0006] Preferably, a metal substrate is arranged inside the frame. An insulating layer is arranged on the metal substrate. An opening is arranged on one side of the insulating layer. A thermal conductive adhesive layer is arranged in the middle of the metal substrate. A chip seat is arranged in the middle of the thermal conductive adhesive layer.
[0007] Preferably, a chip is installed above the chip seat. An outer surface is arranged at the top of the insulating layer. Other external leads are installed on one side of the outer surface. A packaging colloid is installed between the insulating layer and the thermal conductive adhesive layer. Wires are installed on both sides of the chip.
[0008] Preferably, a fixing groove is provided on the frame, a transverse plate and a longitudinal plate are clamped on the fixing groove, and a first limiting groove is provided on the transverse plate and the longitudinal plate, and there are eight groups of the first limiting grooves.
[0009] Preferably, a clamping block is provided on one side of the sealing plate, and there are four groups of the sealing plate and the clamping block, and there are eight groups of the fixing block, the limiting column, the second limiting groove, the spring, the limiting block, and the knob.
[0010] Preferably, a heat conduction port is provided on the outer side of the protective shell, heat collecting pipes are installed on the frame, the transverse plate, and the longitudinal plate, and a bayonet is provided on the frame.
[0011] Preferably, a top cover is provided on the top end of the protective shell, and a sealing ring is provided between the protective shell and the top cover.
[0012] With the above structure, the utility model has the following advantages:
[0013] 1. In the utility model, a buckle mechanism is provided. By manually pressing the knob, the limiting block on the limiting column driven by the knob moves downward in the second limiting groove, and then drives the fixing block on the limiting column to slide downward in the first limiting groove to a proper position. Then rotate the knob, and then drive the fixing block to be clamped in the first limiting groove. This device can place multiple biochips, and at the same time disperse the biochips for placement, which is convenient for the staff to take out the biochips. At the same time, it can avoid contaminating other biochips, effectively protect the performance of the biochips, and help improve the stability, reliability, and service life of the biochip.
[0014] 2. In the utility model, heat collecting pipes are provided, which can provide a certain degree of thermal isolation and thermal stability, prevent the biochip from being damaged due to overheating or overcooling, and ensure the performance stability under different temperature conditions. At the same time, a heat conduction port is provided to dissipate the temperature inside the protective shell and avoid the performance of the biochip being affected by too high temperature. The encapsulation material usually has chemical stability, which can prevent the biochip from being chemically corroded or contaminated, avoid adverse effects on biological samples, ensure the accuracy of biological detection results, and ensure the purity of biological samples and reagents.
[0015] 3. In the utility model, a protective shell and a top cover are provided, which can provide a physical barrier for the biochip to prevent it from being physically damaged by the external environment, such as mechanical impact, vibration, friction, etc. At the same time, the circuit of the biochip is isolated from the external environment to prevent the circuit from being interfered by external electromagnetic fields and ensure the accuracy and stability of signal transmission.
[0016] The above summary is only for the purpose of the specification and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments, and features described above, further aspects, embodiments, and features of the present utility model will be readily apparent by reference to the accompanying drawings and the following detailed description. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments of the present application. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.
[0018] Figure 1 is a schematic structural diagram of a biological chip packaging structure of the present utility model;
[0019] Figure 2 is an exploded view of a biological chip packaging structure of the present utility model;
[0020] Figure 3 is a partial cross-section of a biological chip packaging structure of the present utility model Figure 1 ;
[0021] Figure 4 is a partial cross-section of a biological chip packaging structure of the present utility model Figure 2 。
[0022] As shown in the figure: 1, protective shell; 2, top cover; 3, sealing ring; 4, frame; 5, heat collecting pipe; 6, bayonet; 7, first limiting groove; 8, transverse plate; 9, longitudinal plate; 10, fixing groove; 11, sealing plate; 12, clamping block; 13, fixing block; 14, limiting column; 15, second limiting groove; 16, spring; 17, limiting block; 18, knob; 19, chip; 20, wire; 21, chip seat; 22, external pin; 23, outer surface; 24, insulating layer; 25, opening; 26, encapsulating colloid; 27, heat-conducting adhesive layer; 28, metal substrate; 29, heat-conducting port. DETAILED DESCRIPTION OF THE EMBODIMENTS
[0023] The following will describe in detail the embodiments of the present application. The examples of the embodiments are shown in the drawings, where the same or similar reference numerals represent the same or similar elements or elements with the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary and are only used to explain the present application and should not be construed as a limitation of the present application.
[0024] In the description of the present application, it should be noted that unless otherwise clearly specified and defined, the terms "installed", "connected", and "coupled" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two components or the interaction relationship between two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood according to specific circumstances.
[0025] The following further elaborates on the present utility model in conjunction with the full text:
[0026] Combined with the attached Figures 1 to 4 , a biochip packaging structure includes a protective shell 1. Inside the protective shell 1, a frame 4 is provided. A sealing plate 11 is installed on the frame 4. A second limiting groove 15 is provided on the sealing plate 11. A limiting block 17 is arranged in the second limiting groove 15. A limiting column 14 is fixedly connected to the middle of the limiting block 17. A knob 18 is installed on one side of the limiting column 14. A fixing block 13 is installed on the side of the limiting column 14 away from the knob 18. A spring 16 is installed below the limiting block 17. The limiting column 14 penetrates and is slidably connected to the sealing plate 11. This device can place multiple biochips 19 and disperse the placement of the biochips 19 at the same time, which is convenient for the staff to take out the biochips 19 and avoid contaminating other biochips 19. It can effectively protect the performance of the biochips 19 and help improve the stability, reliability, and service life of the biochip.
[0027] Among them, a metal substrate 28 is provided inside the frame 4, an insulating layer 24 is provided on the metal substrate 28, an opening 25 is provided on one side of the insulating layer 24, a thermal conductive adhesive layer 27 is provided in the middle of the metal substrate 28, a chip socket 21 is provided in the middle of the thermal conductive adhesive layer 27, a wafer 19 is installed above the chip socket 21, an outer surface 23 is provided at the top end of the insulating layer 24, other external pins 22 are installed on one side of the outer surface 23, an encapsulation colloid 26 is installed between the insulating layer 24 and the thermal conductive adhesive layer 27, wires 20 are installed on both sides of the wafer 19, a fixing groove 10 is provided on the frame 4, a transverse plate 8 and a longitudinal plate 9 are clamped on the fixing groove 10, the transverse plate 8 and the longitudinal plate 9 are provided with eight groups of first limiting grooves 7, four groups of a sealing plate 11 and a clamping block 12 are provided, eight groups of a fixing block 13, a limiting post 14, a second limiting groove 15, a spring 16, a limiting block 17 and a knob 18 are provided, a heat conduction port 29 is provided on the outer side of the protective shell 1, the frame 4, the transverse plate 8 and the longitudinal plate 9 are all installed with heat collecting pipes 5. The heat collecting pipes 5 can provide a certain degree of thermal isolation and thermal stability, prevent the biological wafer 19 from being damaged due to overheating or overcooling, and ensure its performance stability under different temperature conditions. At the same time, the heat conduction port 29 is provided to regulate the temperature inside the protective shell 1 so that it always remains at an appropriate temperature and avoid the influence of too high temperature on the performance of the biological wafer 19. The frame 4 is provided with a bayonet 6, a top cover 2 is provided at the top end of the protective shell 1, and a sealing ring 3 is provided between the protective shell 1 and the top cover 2. The encapsulation material usually has chemical stability, can prevent the biological wafer 19 from being chemically corroded or contaminated, avoid having an adverse impact on the biological sample, ensure the accuracy of the biological detection result, and ensure the purity of the biological sample and the reagent.
[0028] Working principle of the present utility model: First, the biochip 19 is disposed on the chip holder 21, and the wire 20 is electrically connected between the chip 19 and the external pin 22. The encapsulation colloid 26 covers the chip 19 and the chip holder 21 and is filled between the external pins 22. The external pins 22 are disposed on the encapsulation colloid 26. Secondly, by increasing the contact area between the insulating layer 24 and the heat-conducting adhesive layer 27 and the metal substrate 28, the bonding force with the metal substrate 28 can be increased, and the bonding strength between the insulating layer 24, the heat-conducting adhesive layer 27 and the metal substrate 28 can be improved to protect the biochip 19. Then, the whole is placed in the cavity composed of the frame 4, the transverse plate 8 and the longitudinal plate 9. The staff manually presses the knob 18, and the knob 18 drives the limiting column 14 to move downward, and then drives the limiting block 17 to move downward in the second limiting groove 15. The limiting block 17 is provided to limit the limiting column 14, and then drives the fixing block 13 on the limiting column 14 to move downward. The fixing block 13 slides to a suitable position in the first limiting groove 7, and then the knob 18 is rotated, and then the fixing block 13 on the limiting column 14 is clamped in the first limiting groove 7, thereby performing secondary protection on the biochip 19. At the same time, when the biochip 19 is taken, other biochips 19 can be avoided from being contaminated, and the performance of the biochip 19 can be effectively protected, which helps to improve the stability, reliability and service life of the biochip. After that, the top cover 2 is covered, and the heat collecting pipe 5 is started through external control. The heat collecting pipe 5 is a prior art and can provide a certain degree of thermal isolation and thermal stability in the protective shell 1 to prevent the biochip 19 from being damaged due to overheating or overcooling and ensure the performance stability under different temperature conditions. At the same time, a heat conduction port 29 is provided to regulate the temperature in the protective shell 1 so that it always remains at a suitable temperature to avoid the performance of the biochip 19 being affected by too high or too low temperature. When the biochip 19 needs to be taken out, the top cover 2 is opened, and then the staff manually rotates the knob 18. Under the action of the spring 16, the knob 18 drives the limiting block 17 on the limiting column 14 to move upward in the second limiting groove 15, and then drives the fixing block 13 on the limiting column 14 to move upward. The fixing block 13 leaves the first limiting groove 7, and the sealing plate 11 is removed to expose the biochip 19 to be taken out.
[0029] The present utility model and its implementation manners have been described above. Such description is not restrictive. What is shown throughout the text is only one of the implementation manners of the present utility model, and the actual structure is not limited thereto. Generally speaking, if those of ordinary skill in the art are inspired by it and design similar structural manners and embodiments to this technical solution without creative work without departing from the creative purpose of the present utility model, they shall fall within the protection scope of the present utility model.
Claims
1. A biochip packaging structure, comprising a protective shell (1), characterized in that: A frame (4) is arranged inside the protective shell (1), a sealing plate (11) is installed on the frame (4), a second limiting groove (15) is arranged on the sealing plate (11), a limiting block (17) is arranged in the second limiting groove (15), a limiting column (14) is fixedly connected to the middle of the limiting block (17), a knob (18) is installed on one side of the limiting column (14), a fixed block (13) is installed on the side of the limiting column (14) away from the knob (18), a spring (16) is installed below the limiting block (17), and the limiting column (14) passes through and is slidably connected to the sealing plate (11).
2. The biochip packaging structure according to claim 1, characterized in that: A metal substrate (28) is arranged in the frame (4), an insulating layer (24) is arranged on the metal substrate (28), an opening (25) is arranged on one side of the insulating layer (24), a heat-conducting adhesive layer (27) is arranged in the middle of the metal substrate (28), and a chip seat (21) is arranged in the middle of the heat-conducting adhesive layer (27).
3. The biochip packaging structure according to claim 2, characterized in that: A chip (19) is installed above the chip seat (21); an outer surface (23) is provided at the top of the insulating layer (24); an external pin (22) is installed on one side of the outer surface (23); a packaging colloid (26) is installed between the insulating layer (24) and the thermal conductive adhesive layer (27); and wires (20) are installed on both sides of the chip (19).
4. The biochip packaging structure according to claim 1, characterized in that: The frame (4) is provided with a fixing groove (10), a transverse plate (8) and a longitudinal plate (9) are clamped on the fixing groove (10), the transverse plate (8) and the longitudinal plate (9) are provided with first limiting grooves (7), and eight groups of the first limiting grooves (7) are provided.
5. The biochip packaging structure according to claim 1, characterized in that: A clamping block (12) is provided on one side of the sealing plate (11), and the sealing plate (11) and the clamping block (12) are provided in four groups, and the fixing block (13), the limiting column (14), the second limiting groove (15), the spring (16), the limiting block (17), and the knob (18) are provided in eight groups.
6. The biochip packaging structure according to claim 1, characterized in that: The outer side of the protective shell (1) is provided with a heat conducting port (29), the frame (4), the transverse plate (8) and the longitudinal plate (9) are all equipped with heat collecting pipes (5), and the frame (4) is provided with a bayonet (6).
7. The biochip packaging structure according to claim 1, characterized in that: A top cover (2) is arranged at the top of the protective shell (1), and a sealing ring (3) is arranged between the protective shell (1) and the top cover (2).