Cell cryopreservation box

By designing an automated cell freezing box, using a clamping pad connected by an extrusion linkage mechanism and an extrusion spring, the problems of easy shaking when moving and difficulty in accessing the test tube in the prior art are solved, and efficient and safe cell freezing operation is achieved.

CN222967785UActive Publication Date: 2025-06-13LINXCELL BIOTECHNOLOGIES
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Patent Information

Application Number
CN202421692766.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-17
Publication Date
2025-06-13
Estimated Expiration
2034-07-17

AI Technical Summary

Technical Problem

The existing cell freezing box is prone to shaking and bumping the tube body when moving, which affects the cell storage status. The test tube has a small gap and is difficult to use, making it easy to cause accidental contact and time-consuming problems.

Method used

A cell freezing box including a box body, a freezing chamber, a first ply plate and a second ply plate is designed. The ply plate is equipped with an extrusion linkage mechanism. The threaded screw rod is driven by a two-way motor to automatically clamp and scale the ply plate. Combined with the clamping pad and telescopic rod connected by the extrusion spring, automatic operation and test tube fixation are realized.

Benefits of technology

The automated operation of the splint is realized, which reduces the time and risk of manual operation and the risk of accidental contact, improves the efficiency and safety of cell freezing, and avoids test tube shaking and rupture.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a cell cryopreservation box in the technical field of cell cryopreservation, which comprises a box body, a cryopreservation chamber arranged in the box body, a plurality of groups of first clamping plates arranged in the cryopreservation chamber and second clamping plates matched with the first clamping plates, and extrusion linkage mechanisms for driving the first clamping plates and the second clamping plates to move relatively are mounted on the first clamping plates and the second clamping plates. The extrusion linkage mechanism comprises a two-way motor arranged at the left ends of the first clamping plate and the second clamping plate and a connecting rod arranged at the right ends of the first clamping plate and the second clamping plate, the two-way motor is started, the first clamping plate and the second clamping plate are pushed by a connecting block to be away from and tightened, and automatic clamping and scaling of the two clamping plates are achieved; manual operation for controlling the distance between the two groups of clamping plates is not needed, the operation is simple, and the automation degree is high; a telescopic rod is arranged at the bottom of a supporting movable block, so that a first clamping plate and a second clamping plate 7 ascend and descend, test tubes are convenient to take and store, and the test tubes descend into the freezing chamber 3 when needing to be frozen, and the cell freezing efficiency is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell cryopreservation, in particular to a cell cryopreservation box. Background Technique

[0002] Cells are the basic units that make up organisms in biology. Cells are dynamic and determine our life states. In order to achieve the long-term storage of cells, the cell cryopreservation technology has emerged. Cell cryopreservation is to place cells in a low-temperature environment to reduce cell metabolism, so that cells can be temporarily separated from the growth state and their cell characteristics can be preserved. In this way, cells can be resuscitated for experiments and medical applications when needed.

[0003] Most of the existing cell cryopreservation boxes are composed of several test tubes inside. When moving, it is easy to shake and bump the tube body, which affects the cell storage state. At the same time, due to the small gap between the tube bodies of the test tubes, when using, it is necessary to take them from inside the cryopreservation box, which is easy to accidentally touch other test tubes and takes time. Therefore, those skilled in the art have provided a cell cryopreservation box to solve the problems raised in the above background technique. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a cell cryopreservation box to solve the problems raised in the above background technique.

[0005] To achieve the above purpose, the utility model provides the following technical solution: A cell cryopreservation box, including a box body, a bottom plate arranged at the bottom of the box body, a cryopreservation chamber opened inside the box body, multiple groups of first clamping plates arranged in the cryopreservation chamber, and second clamping plates cooperating with the first clamping plates. An extrusion linkage mechanism for driving their relative movement is installed on the first clamping plates and the second clamping plates;

[0006] The extrusion linkage mechanism includes a bidirectional motor arranged at the left ends of the first clamping plate and the second clamping plate and a connecting rod at the right ends. The bidirectional motor and the connecting rod are both installed on a supporting movable block. Both output ends of the bidirectional motor are connected with threaded lead screws. Two groups of sliding members are threadedly sleeved on the two groups of threaded lead screws. Two groups of the sliding members are slidably sleeved on the connecting rod. The other ends of the sliding members are fixedly connected with connecting blocks, and the other ends of the connecting blocks are respectively welded to the left and right end faces of the first clamping plate and the second clamping plate.

[0007] Preferably: Convex blocks are arranged at the left and right ends of the first clamping plate and the second clamping plate. The convex blocks are slidably installed in a chute, and the chute is dug on the inner side of the supporting movable block.

[0008] Preferably: A telescopic rod is arranged at the bottom of the supporting movable block, and the other end of the telescopic rod is installed on the bottom plate.

[0009] Preferably, an elastic pad is provided on the bottom plate, and a number of sets of columnar movable members are installed above the elastic pad.

[0010] Preferably, a number of sets of semi-circular placement grooves are provided on the first clamping plate and the second clamping plate, a clamping pad is provided in each set of placement grooves, and the clamping pad is connected to the placement grooves on the first clamping plate and the second clamping plate by compression springs.

[0011] Preferably, the upper end of the box body is movably connected with a cover plate, and a lock is fixedly installed on the cover plate.

[0012] Preferably, a lock is provided on the contact surface of the cover plate, and the sealing ring is located inside the cryopreservation chamber.

[0013] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0014] 1. In the present utility model, when the bidirectional motor 10 is started, the rotation directions of the two screw rods 12 are opposite, driving the sliding members 14 to move towards each other or approach each other, so that the first clamping plate and the second clamping plate are pushed by the connecting block to move away and tighten, realizing the automatic clamping and scaling of the two clamping plates, and no longer requiring manual operation to control the distance between the two clamping plates. The operation is simple and the automation degree is high.

[0015] 2. In the present utility model, the clamping pad connected by the compression spring fixes the freezing test tube, avoiding the shaking of the test tube and achieving a protective effect.

[0016] 3. In the present utility model, through the arrangement of the telescopic rod, the first clamping plate and the second clamping plate are raised and lowered, which is convenient for taking and storing the test tube, and when freezing is required, it descends into the freezing chamber, improving the efficiency of cell cryopreservation. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 is a schematic diagram of the overall structure of the present utility model;

[0018] Figure 2 is a schematic diagram of the internal structure of the cryopreservation chamber of the present utility model;

[0019] Figure 3 is a schematic diagram of the partial structure of the clamping plate of the present utility model;

[0020] Figure 4 is a schematic diagram of the structure of the supporting movable block of the present utility model.

[0021] In the figure: 1. Box body, 2. Cover plate, 3. Cryopreservation chamber, 4. Sealing ring, 5. Lock, 6. First clamping plate, 7. Second clamping plate, 8. Clamping pad, 9. Support movable block, 10. Telescopic rod, 11. Bidirectional motor, 12. Threaded lead screw, 13. Connecting block, 14. Sliding member, 15. Connecting rod, 16. Elastic pad, 17. Columnar movable member, 18. Bottom plate, 19. Convex block, 20. Chute, 21. Compression spring. Detailed implementation manner

[0022] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0023] Please refer to Figures 1 to 4 , in the embodiment of the present invention, a cell cryopreservation box includes a box body 1, a bottom plate 18 provided at the bottom of the box body 1, a cryopreservation chamber 3 opened inside the box body 1, multiple groups of first clamping plates 6 provided in the cryopreservation chamber 3, and a second clamping plate 7 that cooperates with the first clamping plate 6. An extrusion linkage mechanism for driving their relative movement is installed on the first clamping plate 6 and the second clamping plate 7.

[0024] During use, the extrusion linkage mechanism includes a bidirectional motor 11 provided at the left ends of the first clamping plate 6 and the second clamping plate 7 and a connecting rod 15 at the right ends. Both the bidirectional motor 11 and the connecting rod 15 are installed on the support movable block 9. Both output ends of the bidirectional motor 11 are connected with threaded lead screws 12. Two groups of threaded lead screws 12 are threadedly sleeved with sliding members 14. Two groups of sliding members 14 are slidably sleeved on the connecting rod 15. The connecting rod 15 plays a role of support and fixation, so that the first clamping plate 6 and the second clamping plate 7 are kept flat and stable. The other ends of the sliding members 14 are fixedly connected with connecting blocks 13. The other ends of the connecting blocks 13 are respectively welded to the left and right end faces of the first clamping plate 6 and the second clamping plate 7. When the bidirectional motor 10 is started, the rotation directions of the two groups of threaded lead screws 12 are opposite, driving the sliding members 14 to move towards or close to each other, so that the first clamping plate 6 and the second clamping plate 7 are pushed by the connecting blocks 13 to move away and tighten, realizing the automatic clamping and scaling of the two groups of clamping plates, and no longer requiring manual operation to control the distance between the two groups of clamping plates. The operation is simple and the degree of automation is high.

[0025] In one embodiment, specifically, bumps 19 are provided at both the left and right ends of the first clamping plate 6 and the second clamping plate 7. The bumps 19 are slidably installed in the sliding grooves 20, and the sliding grooves 20 are dug on the inner side of the supporting movable block 9. A number of groups of semi-circular placement grooves are provided on the first clamping plate 6 and the second clamping plate 7. A clamping pad 8 is provided in each group of placement grooves. The clamping pad 8 is connected to the placement grooves on the first clamping plate 6 and the second clamping plate 7 by compression springs 21. When the freezing test tube is placed in the freezer, at this time, the freezing test tube is stored between the two clamping plates through the placement groove, and it is not completely fixed. It is easy to hit the wall during movement, resulting in the problem of breakage. Through the relative movement of the bumps 19 at both ends of the first clamping plate 6 and the second clamping plate 7 inside the sliding grooves 20, the two clamping plates are urged to clamp each other. At the same time, the clamping pad 8 connected by the compression spring 21 fixes the freezing test tube, avoiding the shaking of the test tube and achieving the protective effect. When the test tube needs to be taken out, the bidirectional motor 10 is started to make the bumps 19 move away from each other inside the sliding grooves 20, so as to realize the separation between the two clamping plates.

[0026] Specifically, a telescopic rod 10 is provided at the bottom of the supporting movable block 9, and the other end of the telescopic rod 10 is installed on the bottom plate 18. Through the setting of the telescopic rod 10, the first clamping plate 6 and the second clamping plate 7 are raised and lowered, which is convenient for taking and storing the test tube, and when freezing is required, it descends into the freezer 3 to improve the efficiency of cell cryopreservation.

[0027] Among them, an elastic pad 16 is provided on the bottom plate 18, and a number of groups of columnar movable members 17 are installed above the elastic pad 16. The movable members 17 can shrink into the elastic pad 16 to different depths according to different pressures to adapt to the bottom fixation of freezing test tubes with different diameters.

[0028] In one embodiment, specifically, the upper end of the box body 1 is movably connected with a cover plate 2. A lock catch 5 is fixedly installed on the cover plate 2. A lock catch 5 is provided on the contact surface between the cover plate 2 and the cover plate 2. The sealing ring 4 is located inside the cryopreservation chamber 3, which can effectively improve the tightness of the cell cryopreservation box and improve the quality of cell cryopreservation.

[0029] The above is only a preferred specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, according to the technical solution and the inventive concept of the present invention, makes equivalent substitutions or changes, and should be covered within the protection scope of the present invention.

Claims

1. A cell freezing box, comprising a box body (1), a bottom plate (18) arranged at the bottom of the box body (1), a freezing chamber (3) opened inside the box body (1), a plurality of first clamping plates (6) arranged in the freezing chamber (3), and a second clamping plate (7) cooperating with the first clamping plates (6), characterized in that: The first clamping plate (6) and the second clamping plate (7) are provided with a squeezing linkage mechanism for driving the relative movement thereof; The extrusion linkage mechanism comprises a bidirectional motor (11) arranged at the left end of the first clamping plate (6) and the second clamping plate (7) and a connecting rod (15) at the right end. The bidirectional motor (11) and the connecting rod (15) are both installed on the supporting movable block (9). The two output ends of the bidirectional motor (11) are connected to threaded screws (12). Two groups of the threaded screws (12) are threadedly sleeved with sliding members (14). Two groups of the sliding members (14) are slidably sleeved on the connecting rod (15). The other ends of the sliding members (14) are fixedly connected to connecting blocks (13). The other ends of the connecting blocks (13) are respectively welded to the left and right end surfaces of the first clamping plate (6) and the second clamping plate (7).

2. A cell freezing box according to claim 1, characterized in that: The first clamping plate (6) and the second clamping plate (7) are both provided with protrusions (19) at the left and right ends. The protrusions (19) are slidably installed in a slide groove (20). The slide groove (20) is dug inside the supporting movable block (9).

3. A cell freezing box according to claim 2, characterized in that: A telescopic rod (10) is provided at the bottom of the supporting movable block (9), and the other end of the telescopic rod (10) is mounted on the bottom plate (18).

4. A cell freezing box according to claim 3, characterized in that: An elastic pad (16) is arranged on the bottom plate (18), and a plurality of groups of columnar movable parts (17) are installed above the elastic pad (16).

5. A cell freezing box according to claim 2, characterized in that: A plurality of groups of semicircular placement grooves are provided on the first clamping plate (6) and the second clamping plate (7), a clamping pad (8) is provided in each group of placement grooves, and the clamping pad (8) is connected to the placement grooves on the first clamping plate (6) and the second clamping plate (7) via a compression spring (21).

6. A cell freezing box according to claim 1, characterized in that: The upper end of the box body (1) is movably connected to a cover plate (2), and a lock buckle (5) is fixedly mounted on the cover plate (2).

7. A cell freezing box according to claim 6, characterized in that: A lock buckle (5) is provided on the contact surface between the cover plates (2), and the sealing ring (4) is located inside the freezing chamber (3).