Antigen adjuvant emulsifying device for animal immunization

Abstract

The utility model discloses an animal immunization antigen adjuvant emulsifying device which comprises a bottom plate, an emulsifying tank is arranged above the bottom plate, a top cover is fixedly installed on the top side of the emulsifying tank, two round holes are formed in the top side of the top cover, rotating rods are arranged in the two round holes, and the rotating rods are connected with the emulsifying tank. The top ends of the two rotating rods are fixedly connected with a first gear and a second gear in a sleeving mode respectively, the motor operates to drive the first stirring rods to stir mixed liquid in the emulsifying tank, the outer side of the output end of the motor is fixedly connected with a linkage gear in a sleeving mode, and the linkage gear is matched with the first gear and the second gear; when the linkage gear rotates clockwise, a first gear and a second gear can be driven to synchronously rotate anticlockwise, so that two rotating rods synchronously rotate anticlockwise, and a plurality of second stirring rods fixedly mounted on the outer sides of the two rotating rods are used for fully stirring mixed liquid; the plurality of first stirring rods rotate forwards, so that the mixing speed of the mixed liquid is greatly increased, and the emulsifying speed is greatly increased.

Description

Technical Field

[0001] The utility model relates to the technical field of antigen adjuvant emulsification, in particular to an antigen adjuvant emulsifying device for animal immunization. Background Art

[0002] In the experiment of preparing antiserum or antibody, it is necessary to immunize experimental animals with corresponding antigens. Before immunizing the animals, the antigen and adjuvant need to be mixed in a certain proportion to form a "water-in-oil" emulsion. This process is usually called the emulsification of antigen and adjuvant. The traditional emulsification methods mainly include grinding method, syringe injection, ultrasonic oscillation, etc. The first two methods take a long time and the emulsification is not sufficient, while the latter has unknown damage to the structure of the antigen itself.

[0003] A small antigen adjuvant emulsifying device proposed according to the publication number (CN211988064U) includes a support column, a stable base threadedly connected to the support column, a receiving tray embedded in the top opening of the support column through a cross bar, a motor fixedly installed in the receiving tray, a driving gear fixedly connected to the motor, a transmission gear meshing with the driving gear, and a stirring rod fixedly connected to the transmission gear. The stirring rod is horizontally supported and fixed on the support column through a first hoop. The stirring rod is driven by a motor to rotate, and the stirring blades below the stirring rod stir the mixture of antigen and adjuvant in the container to quickly mix the antigen and adjuvant.

[0004] However, in the above scheme, the stirring blades rotate fixedly, which easily leads to uneven mixing, further affecting the processing speed. And during the stirring and emulsifying process, due to the friction between the stirring rod and the liquid, the temperature of the mixture increases, and the mixture with too high temperature will reduce the emulsification quality. Therefore, an antigen adjuvant emulsifying device for animal immunization is proposed to solve the above problems. Summary of the Utility Model

[0005] Aiming at the deficiencies of the prior art, the utility model provides an antigen adjuvant emulsifying device for animal immunization, which solves the problems in the above background art.

[0006] In order to achieve the above purpose, the utility model adopts the following technical scheme:

[0007] An antigen adjuvant emulsifying device for animal immunity, comprising a bottom plate. Above the bottom plate is provided an emulsifying tank. The top side of the emulsifying tank is fixedly installed with a top cover. Two round holes are opened on the top side of the top cover. Rotating rods are arranged in both of the two round holes. First gears and second gears are respectively fixedly sleeved on the top ends of the two rotating rods. A plurality of second stirring rods are respectively fixedly installed on the outer sides of the two rotating rods. The plurality of second stirring rods are arranged on the same horizontal line. An installation frame is fixedly installed on the top side of the top cover. A linkage assembly is arranged between the installation frame and the first gear and the second gear. A circulation assembly is arranged on the top side of the installation frame. Water tanks and a cooling tank are respectively fixedly installed on the top side of the bottom plate. An annular water pipe is fixedly connected to the outer side of the emulsifying tank. A conveying assembly is arranged between the annular water pipe and the water tank.

[0008] Preferably, the linkage assembly includes a motor fixedly installed on the top side of the installation frame. The output end of the motor rotates through the installation frame and the top cover and extends into the emulsifying tank. A linkage gear is fixedly sleeved on the outer side of the output end of the motor. The linkage gear meshes with the first gear and the second gear.

[0009] Preferably, a plurality of first stirring rods are fixedly installed on the outer side of the output end of the motor. The plurality of first stirring rods are not on the same horizontal line as the two groups of second stirring rods.

[0010] Preferably, the conveying assembly includes a first water pump fixedly installed on the top side of the water tank. A suction pipe is fixedly installed on one side of the first water pump. The other end of the suction pipe extends into the water tank. A conveying pipe is fixedly installed on the other side of the first water pump. The other end of the conveying pipe is fixedly connected and communicated with one end of the annular water pipe. The other end of the annular water pipe is fixedly connected with a discharge pipe. The other end of the discharge pipe is fixedly connected to the top side of the cooling tank and is communicated with the cooling tank.

[0011] Preferably, the circulation assembly includes a second water pump fixedly installed on the top side of the installation frame. A connecting pipe is fixedly installed on one side of the second water pump. The other end of the connecting pipe extends into the cooling tank. A discharging pipe is fixedly installed on the other side of the second water pump. The other end of the discharging pipe is fixedly connected to the top side of the water tank and is communicated with the water tank.

[0012] Preferably, a connecting plate is fixedly installed on the inner wall of the emulsifying tank. The other ends of the two rotating rods and the output end of the motor are all rotatably connected to the connecting plate.

[0013] Preferably, a discharge port and a feed port are respectively arranged on the bottom side of the emulsifying tank and the top side of the top cover. A solenoid valve is arranged on the outer side of the discharge port.

[0014] Preferably, a bracket is fixedly installed on the top side of the bottom plate. The number of brackets is three. The other ends of the three brackets are all fixedly connected to the bottom side of the emulsifying tank.

[0015] Compared with the prior art, the beneficial effects of the present utility model are as follows: For the antigen adjuvant emulsifying device for animal immunization, the operation of the motor drives multiple first stirring rods to stir the mixed liquid in the emulsifying tank. Since a linkage gear is fixedly sleeved outside the output end of the motor, and the linkage gear meshes with the first gear and the second gear, when the linkage gear rotates clockwise, it can drive the first gear and the second gear to rotate counterclockwise synchronously, so that the two rotating rods rotate counterclockwise synchronously, and further multiple second stirring rods fixedly installed on the outer sides of the two rotating rods fully stir the mixed liquid. Cooperating with the forward rotation of multiple first stirring rods, the mixing speed of the mixed liquid is greatly increased, and further the emulsifying speed is greatly increased.

[0016] The operation of the first water pump drives the extraction pipe to extract the water source in the water tank, and then the water source is conveyed through the conveying pipe into the annular water pipe. Since the annular water pipe is fixedly connected to the inner and outer sides of the emulsifying tank, when the water source flows in the annular water pipe, it can take away the temperature on the emulsifying tank, and further can take away the heat generated during stirring, so as to ensure the quality of emulsifying the mixed liquid. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 is a three-dimensional schematic diagram of the structure of the present utility model;

[0018] Figure 2 is a front three-dimensional schematic diagram of the structure of the present utility model;

[0019] Figure 3 is a sectional schematic diagram of the structure of the present utility model;

[0020] Figure 4 is the structure of the present utility model Figure 3 partial schematic diagram of part A in;

[0021] Figure 5 is a schematic diagram of some parts of the annular water pipe structure of the present utility model.

[0022] In the figure: 1, bottom plate; 2, bracket; 3, emulsifying tank; 4, top cover; 5, mounting frame; 6, motor; 7, first stirring rod; 8, linkage gear; 9, rotating rod; 10, first gear; 11, second gear; 12, second stirring rod; 13, connecting plate; 14, feed inlet; 15, discharge outlet; 16, solenoid valve; 17, water tank; 18, cooling tank; 19, annular water pipe; 20, first water pump; 21, extraction pipe; 22, conveying pipe; 23, discharge pipe; 24, second water pump; 25, connecting pipe; 26, drainage pipe. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0023] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0024] Embodiment: Refer to Figures 1-5 , an antigen adjuvant emulsifying device for animal immunization, which includes a bottom plate 1. An emulsifying tank 3 is arranged above the bottom plate 1. A top cover 4 is fixedly installed on the top side of the emulsifying tank 3. Two round holes are opened on the top side of the top cover 4. Rotating rods 9 are arranged in both of the two round holes. First gears 10 and second gears 11 are fixedly sleeved on the top ends of the two rotating rods 9 respectively. A plurality of second stirring rods 12 are fixedly installed on the outer sides of the two rotating rods 9 respectively. The plurality of second stirring rods 12 are arranged on the same horizontal line. An installation frame 5 is fixedly installed on the top side of the top cover 4. A linkage assembly is arranged between the installation frame 5, the first gear 10 and the second gear 11. A circulation assembly is arranged on the top side of the installation frame 5. A water tank 17 and a cooling box 18 are fixedly installed on the top side of the bottom plate 1 respectively. An annular water pipe 19 is fixedly connected to the outer side of the emulsifying tank 3. A conveying assembly is arranged between the annular water pipe 19 and the water tank 17. The linkage assembly includes a motor 6 fixedly installed on the top side of the installation frame 5. The output end of the motor 6 rotates through the installation frame 5 and the top cover 4 and extends into the emulsifying tank 3. A linkage gear 8 is fixedly sleeved on the outer side of the output end of the motor 6. The linkage gear 8 meshes with the first gear 10 and the second gear 11. A plurality of first stirring rods 7 are fixedly installed on the outer side of the output end of the motor 6. The plurality of first stirring rods 7 and the two groups of second stirring rods 12 are not on the same horizontal line. A connecting plate 13 is fixedly installed on the inner wall of the emulsifying tank 3. The other ends of the two rotating rods 9 and the output end of the motor 6 are rotatably connected to the connecting plate 13. When the motor 6 operates, it drives the plurality of first stirring rods 7 to stir the mixed liquid in the emulsifying tank 3. And because the linkage gear 8 is fixedly sleeved on the outer side of the output end of the motor 6, the linkage gear 8 will also rotate synchronously. And the linkage gear 8 meshes with the first gear 10 and the second gear 11. So when the linkage gear 8 rotates clockwise, it can drive the first gear 10 and the second gear 11 to rotate counterclockwise synchronously, so that the two rotating rods 9 rotate counterclockwise synchronously. Furthermore, the plurality of second stirring rods 12 fixedly installed on the outer sides of the two rotating rods 9 fully stir the mixed liquid, cooperating with the forward rotation of the plurality of first stirring rods 7 to greatly improve the mixing speed of the mixed liquid. And through the arranged connecting plate 13, it can ensure that the two rotating rods 9 and the output end of the motor 6 can rotate stably.

[0025] Specifically, the conveying component includes a first water pump 20 fixedly installed on the top side of the water tank 17. One side of the first water pump 20 is fixedly installed with a suction pipe 21, and the other end of the suction pipe 21 extends into the water tank 17. The other side of the first water pump 20 is fixedly installed with a conveying pipe 22. The other end of the conveying pipe 22 is fixedly connected and communicated with one end of the annular water pipe 19. The other end of the annular water pipe 19 is fixedly connected with a discharge pipe 23, and the other end of the discharge pipe 23 is fixedly connected to the top side of the cooling tank 18 and communicated with the cooling tank 18. By operating the first water pump 20, the suction pipe 21 is driven to extract the water source in the water tank 17, and then the water source is conveyed into the annular water pipe 19 through the conveying pipe 22. Since the annular water pipe 19 is fixedly connected to the inside and outside of the emulsifying tank 3, when the water source flows in the annular water pipe 19, it can take away the temperature on the emulsifying tank 3, and further can take away the heat generated during stirring, thereby ensuring the quality of the emulsification of the mixed liquid. After the water flow passes through the annular water pipe 19, it will flow into the cooling tank 18 along the discharge pipe 23 for natural cooling.

[0026] Specifically, the circulating component includes a second water pump 24 fixedly installed on the top side of the mounting frame 5. One side of the second water pump 24 is fixedly installed with a communicating pipe 25, and the other end of the communicating pipe 25 extends into the cooling tank 18. The other side of the second water pump 24 is fixedly installed with a discharge pipe 26, and the other end of the discharge pipe 26 is fixedly connected to the top side of the water tank 17 and communicated with the water tank 17. By setting the second water pump 24, after the warm water is naturally cooled in the cooling tank 18 for a period of time, the second water pump 24 can be operated to drive the communicating pipe 25 to extract the cooled water source, and then the water source is conveyed into the water tank 17 through the discharge pipe 26, thereby realizing the recycling of water resources.

[0027] Specifically, a discharge port 15 and a feed port 14 are respectively arranged on the bottom side of the emulsifying tank 3 and the top side of the top cover 4. An electromagnetic valve 16 is arranged on the outside of the discharge port 15. A bracket 2 is fixedly installed on the top side of the bottom plate 1, and the number of brackets 2 is three. The other ends of the three brackets 2 are all fixedly connected to the bottom side of the emulsifying tank 3. By setting the electromagnetic valve 16, after the mixing is completed, by placing the collection container below the discharge port 15, and then the electromagnetic valve 16 operates to discharge the emulsified mixed liquid from the discharge port 15 into the collection container.

[0028] All the electrical components appearing in this article are electrically connected to the external main controller and 220V mains electricity, and the main controller can be a conventional known device such as a computer for control.

[0029] In use: Before emulsifying the antigen and adjuvant, pour the required antigen and adjuvant into the emulsifying tank 3 through the feed port 14 in sequence. Then start the motor 6 to drive multiple first stirring rods 7 to stir the mixed liquid in the emulsifying tank 3. Since the linkage gear 8 is fixedly sleeved on the outer side of the output end of the motor 6, the linkage gear 8 will also rotate synchronously. The linkage gear 8 meshes with the first gear 10 and the second gear 11. Therefore, when the linkage gear 8 rotates clockwise, it can drive the first gear 10 and the second gear 11 to rotate counterclockwise synchronously, so that the two rotating rods 9 rotate counterclockwise synchronously. Furthermore, multiple second stirring rods 12 fixedly installed on the outer sides of the two rotating rods 9 fully stir the mixed liquid, cooperating with the forward rotation of the multiple first stirring rods 7 to greatly improve the mixing speed of the mixed liquid. During the stirring process of the multiple first stirring rods 7 and the multiple second stirring rods 12, due to the friction with the liquid, the temperature of the mixed liquid will increase. At this time, start the first water pump 20 to drive the extraction pipe 21 to extract the water source in the water tank 17, and then transport the water source through the delivery pipe 22 to the annular water pipe 19. Since the annular water pipe 19 is fixedly connected to the inner and outer sides of the emulsifying tank 3, when the water source flows in the annular water pipe 19, it can take away the temperature on the emulsifying tank 3, and further can take away the heat generated during stirring, thus ensuring the quality of the emulsification of the mixed liquid. The water flow will flow into the cooling tank 18 along the discharge pipe 23 after flowing through the annular water pipe 19. After the warm water naturally cools in the cooling tank 18 for a period of time, start the second water pump 24 to drive the connecting pipe 25 to extract the cooled water source, and then transport the water source through the discharge pipe 26 to the water tank 17, thus realizing the recycling of water resources.

[0030] It should be noted that in this text, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device.

[0031] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An antigen adjuvant emulsification device for animal immunization, comprising a bottom plate (1), characterized in that: An emulsification tank (3) is arranged above the bottom plate (1), a top cover (4) is fixedly mounted on the top side of the emulsification tank (3), two round holes are provided on the top side of the top cover (4), a rotating rod (9) is arranged in each of the two round holes, the top ends of the two rotating rods (9) are respectively fixedly sleeved with a first gear (10) and a second gear (11), a plurality of second stirring rods (12) are respectively fixedly mounted on the outer sides of the two rotating rods (9), and the plurality of second stirring rods (12) are arranged on the same horizontal line, a mounting frame (5) is fixedly mounted on the top side of the top cover (4), a linkage assembly is arranged between the mounting frame (5) and the first gear (10) and the second gear (11), a circulation assembly is arranged on the top side of the mounting frame (5), a water tank (17) and a cooling box (18) are respectively fixedly mounted on the top side of the bottom plate (1), an annular water pipe (19) is fixedly connected to the outer side of the emulsification tank (3), and a conveying assembly is arranged between the annular water pipe (19) and the water tank (17).

2. The antigen adjuvant emulsification device for animal immunization according to claim 1, characterized in that: The linkage assembly comprises a motor (6) fixedly mounted on the top side of a mounting frame (5); the output end of the motor (6) rotates through the mounting frame (5) and the top cover (4) and extends into the emulsification tank (3); a linkage gear (8) is fixedly sleeved on the outer side of the output end of the motor (6); the linkage gear (8) is matched with the first gear (10) and the second gear (11).

3. The antigen adjuvant emulsification device for animal immunization according to claim 2, characterized in that: A plurality of first stirring rods (7) are fixedly mounted on the outer side of the output end of the motor (6), and the plurality of first stirring rods (7) and the two groups of second stirring rods (12) are not located on the same horizontal line.

4. The antigen adjuvant emulsification device for animal immunization according to claim 1, characterized in that: The conveying assembly comprises a first water pump (20) fixedly mounted on the top side of a water tank (17), an extraction pipe (21) fixedly mounted on one side of the first water pump (20), the other end of the extraction pipe (21) extending into the water tank (17), a conveying pipe (22) fixedly mounted on the other side of the first water pump (20), the other end of the conveying pipe (22) being fixedly connected to and communicating with one end of an annular water pipe (19), the other end of the annular water pipe (19) being fixedly connected to a discharge pipe (23), the other end of the discharge pipe (23) being fixedly connected to the top side of a cooling box (18) and communicating with the cooling box (18).

5. The antigen adjuvant emulsification device for animal immunization according to claim 1, characterized in that: The circulation assembly comprises a second water pump (24) fixedly mounted on the top side of a mounting frame (5), a connecting pipe (25) fixedly mounted on one side of the second water pump (24), the other end of the connecting pipe (25) extending into the cooling box (18), and a discharge pipe (26) fixedly mounted on the other side of the second water pump (24), the other end of the discharge pipe (26) fixedly connected to the top side of a water tank (17) and communicating with the water tank (17).

6. The antigen adjuvant emulsification device for animal immunization according to claim 1, characterized in that: A connecting plate (13) is fixedly mounted on the inner wall of the emulsifying tank (3), and the other ends of the two rotating rods (9) and the output end of the motor (6) are both rotatably connected to the connecting plate (13).

7. The antigen adjuvant emulsification device for animal immunization according to claim 1, characterized in that: The bottom side of the emulsification tank (3) and the top side of the top cover (4) are respectively provided with a discharge port (15) and a feed port (14), and a solenoid valve (16) is provided outside the discharge port (15).

8. The antigen adjuvant emulsification device for animal immunization according to claim 1, characterized in that: A bracket (2) is fixedly mounted on the top side of the bottom plate (1), the number of the brackets (2) is three, and the other ends of the three brackets (2) are all fixedly connected to the bottom side of the emulsification tank (3).

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