Medicament isolation packaging bottle

Abstract

The utility model belongs to the technical field of medical instruments, and particularly discloses a medicament isolation packaging bottle. The medicament isolation packaging bottle comprises a bottle cap, a bottle body and an isolation piece arranged in the bottle body, the internal space of the bottle body is divided into at least two independent spaces by the isolation piece, and a communicating piece for controlling the closing and communicating states of the two adjacent spaces is further arranged in the bottle body. According to the medicament isolation packaging bottle provided by the utility model, the isolation piece and the communicating piece are arranged in the bottle body, so that the pollution risk can be effectively reduced, the safety is improved, and the operation process of an operator can be simplified.

Description

Technical Field

[0001] The utility model belongs to the technical field of medical devices, and particularly relates to a medicament isolation packaging bottle. Background Art

[0002] Existing medical medicament containers usually use a single chamber to place medicaments. Although using traditional single-chamber medicament containers can ensure the compliance of medicaments during storage, for some special medicaments, such as biological agents, products with unstable active ingredients, etc., this medicament packaging method has many inconveniences and possibilities of contamination in actual use. Specifically, when it is necessary to dilute, dissolve or compound medicaments, users need to manually put the medicaments in the single-chamber container and diluents or solvents stored in other containers into the same chamber for mixing. This process is not only time-consuming and laborious, but also due to different operation methods of different operators, the concentration of the finally prepared liquid medicine will vary, thus affecting the consistency and effectiveness of treatment. In addition, manual mixing will also increase the risk of drug contamination and may endanger the safety of patients.

[0003] Therefore, there is an urgent need in the market for a new type of medicament packaging device that can simplify the process of preparing liquid medicine, reduce the errors caused by manual operation, and reduce the possibility of medicament contamination on the premise of ensuring the stability and effectiveness of medicaments. Summary of the Invention

[0004] In order to solve the above problems, the utility model provides a medicament isolation packaging bottle, which includes a bottle cap, a bottle body and an isolation member arranged in the bottle body. The isolation member divides the internal space of the bottle body into at least two independent spaces, and a communication member for controlling the closed and connected states between adjacent two spaces is also arranged in the bottle body.

[0005] Further, the isolation member includes at least one isolation part connected to the bottle body and a sealing part connected to the isolation part.

[0006] Further, the isolation part is in a circular ring structure, and the sealing part is arranged at the central hole of the isolation part.

[0007] Further, the isolation part is parallel to the bottom surface of the bottle body or is arranged at a certain angle, and the upper surface and / or the lower surface of the isolation part is / are plane or curved surface; when the upper surface and / or the lower surface of the isolation part is / are curved surface, its thickness gradually increases from the center to the periphery.

[0008] Further, a retaining piece is embedded on the upper surface and / or the lower surface of the sealing part, and the retaining piece is in contact with the isolation part.

[0009] Further, the communication member is a tapered needle, the diameter of the tapered needle gradually decreases from the top to the bottom, and a plurality of through holes are provided.

[0010] Further, the connecting member includes at least one connecting needle for piercing the sealing portion to connect adjacent spaces, and a pushing plate disposed at the top of the connecting needle.

[0011] Further, a first groove for the connecting needle to extend into is provided above the sealing portion.

[0012] Further, a plurality of through holes are provided on the side wall of the connecting needle along its length direction, and a tip is provided at the bottom of the connecting needle.

[0013] Further, when the number of spaces in the bottle body is 2, the length of the connecting needle is greater than the thickness of the sealing portion; when the number of spaces in the bottle body is more than 2, the total length of the connecting needles is greater than the sum of the height of the middle space and the thicknesses of all the sealing portions.

[0014] Further, a second groove is provided at the center of the top of the pushing plate.

[0015] Further, the pushing plate is funnel-shaped.

[0016] Further, the side wall of the connecting needle adjacent to the through hole is a curved surface structure with a smooth transition.

[0017] In summary, the present utility model includes at least one of the following beneficial technical effects:

[0018] 1. Improving the stability of the liquid medicine:

[0019] By storing the pharmaceutical ingredients separately, chemical reactions or degradation caused by premature mixing of the pharmaceuticals are avoided, thereby maintaining the long-term stability of the pharmaceutical ingredients;

[0020] 2. Ensuring the consistency of the liquid medicine concentration:

[0021] By pre-placing a quantitative amount of the pharmaceutical and its diluent or solvent, etc. into a specific space, it is ensured that the pharmaceutical ingredients are mixed in a preset ratio each time of use, avoiding concentration differences caused by different operators. The effectiveness of the pharmaceutical can be maximized, thereby improving the treatment effect;

[0022] 3. Reducing the risk of contamination:

[0023] The pharmaceutical isolation packaging bottle is a disposable sealed package, and the operation is simple. The pharmaceutical and the diluent or solvent, etc. are mixed inside the packaging bottle, reducing the chance of the pharmaceutical being exposed to the external environment, reducing the risk of contamination, and ensuring the quality and safety of the pharmaceutical;

[0024] 4. Enhancing safety:

[0025] By reducing the manual operation steps, the possibility of operation errors is reduced, and the safety of the entire use process is improved;

[0026] 5. Simplifying the operation process:

[0027] The operator does not need to perform additional liquid medicine transfer steps and can achieve the mixing of medicine components in one bottle body through simple operations;

[0028] 6. Adapt to various types of medicines:

[0029] Whether the medicine components are in solid or liquid form, this packaging bottle can be applicable, improving the versatility and flexibility of the packaging bottle;

[0030] 7. Reduce medical waste:

[0031] The packaging bottle is designed compactly, reducing the usage amount of materials and at the same time reducing the waste generated by manual mixing, such as syringes, etc. Description of the Drawings

[0032] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required to be used in the embodiments. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0033] Figure 1 It is a cross-sectional view of the liquid medicine separation packaging bottle (2 independent spaces) of the present invention;

[0034] Figure 2 It is a cross-sectional view of the liquid medicine separation packaging bottle (3 independent spaces) of the present invention;

[0035] Figure 3 It is a cross-sectional view of the liquid medicine separation packaging bottle (2 independent spaces) of the present invention;

[0036] Figure 4 It is a top view of the separator of the present invention;

[0037] Figure 5a It is a cross-sectional view of the separator of the present invention;

[0038] Figure 5b It is a cross-sectional view of the separator of the present invention;

[0039] Figure 5c It is a cross-sectional view of the separator of the present invention;

[0040] Figure 5d It is a cross-sectional view of the separator of the present invention;

[0041] Figure 5e It is a cross-sectional view of the separator of the present invention;

[0042] Figure 5fCross-sectional view of the separator of the present utility model;

[0043] Figure 5g Cross-sectional view of the separator of the present utility model;

[0044] Figure 5h Cross-sectional view of the separator of the present utility model;

[0045] Figure 5i Cross-sectional view of the separator of the present utility model;

[0046] Figure 6 Schematic structural view of the connecting member of the present utility model;

[0047] Figure 7 Schematic structural view of the connecting member of the present utility model;

[0048] Figure 8 Partial cross-sectional view of the connecting needle of the present utility model.

[0049] In the figure: 1, bottle cap; 2, bottle body; 3, separator; 31, separation part; 32, sealing part; 33, baffle; 34, first groove; 4, connecting member; 41, connecting needle; 42, push plate; 43, through hole; 44, tip; 45, second groove; 5, sealing cover. Detailed implementation manners

[0050] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying Figures 1-7 drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all of the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0051] An embodiment of the present application discloses a pharmaceutical isolation packaging bottle. Referring to Figure 1 and Figure 2 , a pharmaceutical isolation packaging bottle includes a bottle cap 1, a bottle body 2, and a separator 3 disposed inside the bottle body 2. The separator 3 divides the internal space of the bottle body 2 into at least two independent spaces, and a connecting member 4 for controlling the closed and connected states between adjacent two spaces is further disposed inside the bottle body 2.

[0052] Among them, the material of the bottle body is not specifically limited here and any material that can be used to hold the medicament can be adopted, including but not limited to glass, plastics (such as polypropylene (PP), polyethylene (PE), polyester (PET)), ceramics, metals, etc. The structure and material of the bottle cap are also not specifically limited. The structure of the bottle cap can be specifically adjusted according to its material, but it needs to satisfy the function of sealing the bottle body. Common structures include but are not limited to a rubber stopper and a combination of a rubber stopper and an aluminum cap. The materials of the bottle cap include but are not limited to rubber, aluminum metal, etc., and it needs to satisfy the function of being pierced to achieve the mixing of the medicament. The structure of the separator is not specifically limited here, as long as it can satisfy the requirement of dividing the internal space of the bottle body into at least two independent spaces. For example, by horizontally arranging a circular rubber sheet in the bottle body, the internal space of the bottle body can be divided into at least two independent spaces. The number and volume of the independent spaces can be adjusted according to the preparation requirements of the medicament. The number of independent spaces can be Figure 1 the two shown in Figure 2 the three shown in, or can be four, five or even more. The contents of each space can be set according to the properties (such as density, etc.) of the medicament, diluent, solvent, etc. When necessary, negative pressure can be set in one or more spaces to achieve the effect that the medicament, diluent, solvent, etc. quickly flow from one space into another space. The contents of each space can be either solid or liquid, but the contents in at least one space must be liquid. For example, when the number of spaces is two, the spaces from top to bottom can be set in three ways: liquid + solid, solid + liquid or liquid + liquid; when the number of spaces is three, the spaces from top to bottom can be set in seven ways: liquid + liquid + solid, liquid + solid + liquid, solid + liquid + liquid, liquid + solid + solid, solid + liquid + solid, solid + solid + liquid, liquid + liquid + liquid, and so on. The connecting member is used to control the closed and connected states between adjacent two spaces and can be adjusted accordingly according to the specific structure of the separator. The triggering methods of the connecting member include but are not limited to inserting a straw, syringe, infusion set, atomization device, etc. from the bottle cap, and are not specifically limited here. In this way, the mixing sequence and mixing method of the medicament can be flexibly controlled according to needs to ensure the accuracy and consistency of the medicament preparation.

[0053] The liquid separation bottle of this embodiment is suitable for holding medicaments of types such as oral liquids, injections, atomization inhalants, etc.

[0054] Working principle: When preparing the medicine, hold the medicine bottle and insert the straw, the needle of the syringe / infuser, or the puncture column of the atomizing device (refer to the vaccine atomizing device disclosed in the utility model patent with the application number 202121737266.6) through the bottle cap, triggering the connecting member, and instantly converting the adjacent two spaces in the bottle body from a closed state to a connected state. At this time, the medicine, diluent or solvent, etc. in the adjacent spaces can be mixed with each other. In addition, the mixing of the medicine, diluent or solvent, etc. in different spaces can be adjusted by controlling the depth of insertion of the straw, the needle of the syringe / infuser, or the puncture column of the atomizing device into the bottle body. For example, two partition members are provided in the bottle body, forming three independent spaces. At this time, the operator can first control the straw, the needle of the syringe / infuser, or the puncture column of the atomizing device to insert into the bottle body to a first depth (such as about 1 cm), so that the first space and the second space are connected, while the third space and the second space are still in a sealed state. After the medicine, diluent or solvent, etc. in the first space and the second space are mixed, then control the straw, the needle of the syringe / infuser, or the puncture column of the atomizing device to insert into the bottle body to a second depth (such as about 2 cm), so that the third space and the second space are connected, and further mix the medicine, diluent or solvent, etc. in the three spaces. This kind of operation is especially suitable for situations with strict requirements on the mixing sequence. During the operation, the operator can, according to his own habits and the preset mixing effect, etc., such as holding the bottle body and shaking the bottle cap up and down, to achieve the effect of fully mixing the medicine with the diluent or solvent, etc. In this way, not only can the pollution risk be effectively reduced and the safety be increased, but also the operation process of the operator can be simplified.

[0055] Refer to Figure 3 and Figure 4 , the partition member 3 includes at least one partition part 31 connected to the bottle body 2 and a sealing part 32 connected to the partition part 31. Preferably, the partition part 31 is in an annular structure, and the sealing part 32 is arranged at the central hole of the partition part 31.

[0056] Among them, the partition part is connected to the inner side wall of the bottle body, preferably integrally formed to ensure the firmness and sealing performance of the connection. The sealing part is connected to the partition part, preferably by an interference connection method, so that a contact pressure is generated between the sealing part and the partition part, thereby increasing the tightness of the connection and ensuring good sealing performance. The design of the sealing part needs to meet the requirement that it can be pierced by the connecting member (such as a connecting needle) when an external force is applied, so as to realize the connection between adjacent spaces when needed. Preferably, the sealing part is cylindrical. In this embodiment, by providing that the partition member includes a partition part and a sealing part, it is easier to connect the partition member with the bottle body, and at the same time, a better sealing effect can be achieved.

[0057] Refer to Figures 5a-5i, the isolation part 31 is arranged parallel to or at an angle to the bottom surface of the bottle body 2, and the upper surface and / or the lower surface of the isolation part 31 is a plane or a curved surface; when the upper surface and / or the lower surface of the isolation part 31 is a curved surface, its thickness gradually increases from the center to the periphery. Among them, the isolation part is preferably made of glass material and is integrally formed with the bottle body to ensure the firmness and tightness of the connection. The sealing part is preferably made of rubber material to provide good sealing performance. When the structure of the isolation part is as Figures 5h-5i shown, after the connecting part pierces the sealing part, it is necessary to hold the bottle body at a certain angle so that the contents in each space can fully flow into other spaces.

[0058] Referring to Figure 5e , a retaining piece 33 is embedded on the upper surface and / or the lower surface of the sealing part 32, and the retaining piece 33 is in contact with the isolation part 31 to further increase the connection tightness between the sealing part and the isolation part.

[0059] Referring to Figure 6 , the connecting part 4 includes at least one connecting needle 41 for piercing the sealing part 32 to connect adjacent spaces, and a push plate 42 arranged at the top of the connecting needle 41.

[0060] Among them, the connecting needle is used to pierce the sealing part, and the length of the connecting needle is long enough to connect two adjacent spaces. When the operator inserts a straw, a syringe, an infusion set or an atomization device from the bottle cap, the push plate receives the pressure of the straw, the syringe, the infusion set or the atomization device and moves downward along the bottle body, thereby driving the connecting needle to move downward along the bottle body and piercing the sealing part to control the closed and connected states between two adjacent spaces. The structure of the connecting part in this embodiment is simple, and the closed and connected states between two adjacent spaces can be controlled only by two components.

[0061] Referring to Figure 1 , the connecting part is a tapered needle, the diameter of which gradually decreases from the top to the bottom, and a plurality of through holes 43 are provided on the needle body. At this time, the isolation part can be a rubber sheet, which is arranged inside the bottle body by interference connection, or the rubber sheet can be fixed by arranging a groove on the inner side wall of the bottle body. A sealing cover 5 can also be arranged at the bottom of the bottle body to facilitate filling the medicine. The structure of the connecting part in this embodiment is simple and the operation is convenient.

[0062] As Figure 5c , 5d , 5f, 5g, 5h shown, a first groove 34 for the connecting needle 41 to extend into is provided above the sealing part 32.

[0063] In this embodiment, by providing the first groove, it is used to guide and limit the position of the connecting needle, ensuring that the connecting needle can move accurately along the predetermined path when piercing the sealing part, improving the accuracy and reliability of the connecting needle piercing, thereby avoiding the situation that the connecting needle deviates or the piercing fails during the piercing process, and ensuring the consistency and effectiveness of the medicine mixing process.

[0064] Refer to Figure 6 , a plurality of through holes 43 are provided along the length direction of the side wall of the connecting needle 41, and a tip 44 is provided at the bottom of the connecting needle 41.

[0065] Among them, in this embodiment, by providing a plurality of through holes, the flow rate of the medicament or diluent and solvent can be increased, the mixing speed can be improved, and the high efficiency of medicament mixing can be ensured; by providing a tip, the connecting needle can more easily pierce the sealing portion, reducing the puncture difficulty and ensuring the smoothness of the puncture process. Preferably, the distance between two adjacent through holes is the same as the thickness of the center of the sealing portion to ensure as small a dead volume as possible.

[0066] Refer to Figure 6 , when the number of spaces in the bottle body 2 is 2, the length of the connecting needle 41 is greater than the thickness of the sealing portion 32. When the number of spaces in the bottle body 2 is more than 2, the total length of the connecting needle 41 is greater than the sum of the height of the middle space and the thicknesses of all the sealing portions 32.

[0067] In this embodiment, by limiting the length of the connecting needle, it can be ensured that the connecting needle is long enough to penetrate the sealing portion. Specifically: when the number of spaces in the bottle body 2 is 2, the length of the connecting needle 41 is designed to be greater than the thickness of the sealing portion 32 to ensure that the connecting needle 41 can smoothly penetrate the sealing portion 32 and realize the connection between two adjacent spaces. When the number of spaces in the bottle body 2 is more than 2, the total length of the connecting needle 41 needs to be greater than the sum of the height of the middle space and the thicknesses of all the sealing portions 32 to ensure that the connecting needle 41 can penetrate each sealing portion 32 in sequence and realize the connection between all adjacent spaces.

[0068] Refer to Figure 6 , a second groove 45 is provided at the center of the top of the push plate 42.

[0069] Refer to Figure 7 , the push plate 42 is funnel-shaped.

[0070] In this embodiment, by providing a second groove at the center of the top of the push plate or setting the push plate to be funnel-shaped, when the operator uses a straw, syringe, infusion set or atomization device to trigger the connection device, the connecting needle can smoothly penetrate the sealing portion after piercing the bottle cap, playing a positioning role, thereby reducing the risk that the connecting needle cannot smoothly penetrate the sealing portion due to operator error (such as the needle being inserted obliquely). In summary, this embodiment not only improves the speed and efficiency of medicament mixing, but also enhances the simplicity and reliability of the operation, ensuring the smooth progress of the medicament mixing process.

[0071] Refer to Figure 8 , the side wall of the connecting needle 41 adjacent to the through hole 43 is a curved surface structure with a smooth transition.

[0072] In this embodiment, by defining the structure of the connecting needle, it is possible to maximize the avoidance of friction between the connecting needle and the sealing part during the puncture process, thereby preventing uneven force application and generating particles.

[0073] The above are all preferred embodiments of this application. The protection scope of this application is not limited thereby. Therefore, all equivalent changes made according to the structure, shape, and principle of this application shall be covered within the protection scope of this application.

Claims

1. A pharmaceutical isolation packaging bottle, characterized in that: The pharmaceutical isolation packaging bottle comprises a bottle cap (1), a bottle body (2), and an isolation member (3) arranged in the bottle body (2); the isolation member (3) divides the internal space of the bottle body (2) into at least two independent spaces; and a connecting member (4) for controlling the closed and connected states between two adjacent spaces is also arranged in the bottle body (2).

2. The pharmaceutical isolation packaging bottle according to claim 1, characterized in that: The isolating member (3) comprises at least one isolating portion (31) connected to the bottle body (2) and a sealing portion (32) connected to the isolating portion (31).

3. The pharmaceutical isolation packaging bottle according to claim 2, characterized in that: The isolation portion (31) is a circular ring-shaped structure, and the sealing portion (32) is arranged at the central hole of the isolation portion (31).

4. The pharmaceutical isolation packaging bottle according to claim 3, characterized in that: The isolation portion (31) is parallel to or arranged at a certain angle to the bottom surface of the bottle body (2), and the upper surface and / or the lower surface of the isolation portion (31) is a plane or a curved surface; when the upper surface and / or the lower surface of the isolation portion (31) is a curved surface, its thickness gradually increases from the center to the periphery, and a baffle (33) is embedded in the upper surface and / or the lower surface of the sealing portion (32), and the baffle (33) is in contact with the isolation portion (31).

5. The pharmaceutical isolation packaging bottle according to claim 2, characterized in that: The connecting piece (4) comprises at least one connecting needle (41) for piercing the sealing portion (32) to connect adjacent spaces, and a push plate (42) arranged on the top of the connecting needle (41).

6. The pharmaceutical isolation packaging bottle according to claim 5, characterized in that: The connecting piece (4) is a conical needle, the diameter of which gradually decreases from the top end to the bottom end, and is provided with a plurality of through holes (43), and the side walls of the connecting needle (41) adjacent to the through holes (43) are a curved surface structure with a smooth transition.

7. The medicine isolation packaging bottle according to claim 5, characterized in that: A first groove (34) for the connecting needle (41) to extend into is provided above the sealing portion (32).

8. The pharmaceutical isolation packaging bottle according to claim 5, characterized in that: The side wall of the connecting needle (41) is provided with a plurality of through holes (43) along its length direction, and the bottom of the connecting needle (41) is provided with a tip (44).

9. The pharmaceutical isolation packaging bottle according to claim 5, characterized in that: When the number of spaces in the bottle body (2) is two, the length of the connecting needle (41) is greater than the thickness of the sealing portion (32); when the number of spaces in the bottle body (2) is more than two, the total length of the connecting needle (41) is greater than the sum of the height of the intermediate space and the thickness of all the sealing portions (32).

10. The medicine isolation packaging bottle according to claim 5, characterized in that: A second groove (45) is provided at the center of the top of the push plate (42), or the push plate (42) is funnel-shaped.

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