Heat preservation box and automatic liquid nitrogen tank

Abstract

The utility model discloses a heat preservation box and an automatic liquid nitrogen container, the heat preservation box is used for being arranged on the automatic liquid nitrogen container, the heat preservation box comprises a box body, a box door and a temperature adjusting module, the box door is arranged on the box body in an opening and closing mode, and the temperature adjusting module is arranged in the box body; when the incubator is used, the temperature in the incubator body is low by adjusting the temperature adjusting module, and the biological tissue taken out from the automatic liquid nitrogen tank is placed in the incubator body of the incubator to be stored. The heat preservation box is arranged at the outlet of the automatic liquid nitrogen tank, and the temperature in the box body is adjusted through the temperature adjusting module, so that the biological tissue can be continuously in a low-temperature environment, and the poor preservation effect caused by repeated refrigeration of the biological tissue is avoided.

Description

Technical Field

[0001] The utility model belongs to the technical field of cryopreservation, and particularly relates to a heat preservation box and an automatic liquid nitrogen tank. Background Art

[0002] A liquid nitrogen tank is a common freezing storage container, which is widely used in hospitals and laboratories, mainly for storing biological tissues such as blood and stem cells; the traditional liquid nitrogen tank is made of double-layer stainless steel for the tank body. The cryopreservation tubes storing biological tissues are placed on the cryopreservation rack, and then the cryopreservation rack is placed in the tank body. By introducing liquid nitrogen into the tank body, the biological tissues in the tank body are in a low-temperature environment of more than one hundred degrees Celsius below zero, so as to achieve the purpose of long-term preservation.

[0003] However, a cryopreservation rack stores multiple biological tissues. It takes a long time to find a certain biological tissue, resulting in other biological tissues being exposed to normal temperature conditions and then entering the tank body for refrigeration again. Repeated refrigeration causes poor preservation effect of the biological tissues. Summary of the Utility Model

[0004] In view of this, the purpose of the utility model is to provide a heat preservation box, which solves the problem that when a user takes biological tissues from an existing liquid nitrogen tank, multiple biological tissues are repeatedly refrigerated, resulting in poor preservation effect.

[0005] The purpose of the utility model also lies in providing an automatic liquid nitrogen tank applying the heat preservation box.

[0006] In order to achieve the above purpose, the first technical solution of the utility model is realized as follows: a heat preservation box for being arranged on an automatic liquid nitrogen tank, the heat preservation box includes a box body, a box door and a temperature adjustment module. The box door is arranged on the box body in an openable and closable manner, and the temperature adjustment module is arranged in the box body; during use, the temperature in the box body is adjusted to be low through the temperature adjustment module, and the biological tissues taken out from the automatic liquid nitrogen tank are placed in the box body of the heat preservation box for preservation.

[0007] Furthermore, the heat preservation box further includes a control module, and the temperature adjustment module is connected to the control module.

[0008] Furthermore, the temperature adjustment module includes a temperature measurement unit and a temperature adjustment unit, and both the temperature measurement unit and the temperature adjustment unit are connected to the control module.

[0009] Furthermore, the temperature measurement unit includes at least one temperature sensor, at least one of the temperature sensors is arranged in the box body, and at least one of the temperature sensors is electrically connected to the control module.

[0010] Further, the temperature control unit includes a pipeline, a liquid inlet valve, and at least one nozzle. The pipeline is arranged inside the box body. The liquid inlet valve and the nozzle are both arranged on the pipeline, and the liquid inlet valve is electrically connected to the control module.

[0011] Further, a liquid outlet is arranged at the bottom of the box body.

[0012] Further, the incubator further includes an air outlet module arranged at the top of the box body.

[0013] Further, an air outlet is arranged at the top of the box body and is in communication with the inside thereof; the air outlet module includes a guide plate and an exhaust fan, and the exhaust fan and the guide plate are located on both sides of the air outlet.

[0014] Further, a slidable air baffle is arranged on the box body, and the air baffle is located at the position of the box door.

[0015] The first technical solution of the present utility model is realized as follows: An automatic liquid nitrogen tank includes a tank body and the above-mentioned incubator, and the inside of the tank body is isolated from the inside of the incubator through a plug cover.

[0016] Compared with the prior art, the beneficial effects of the present utility model are as follows: By arranging an incubator at the outlet of the automatic liquid nitrogen tank and using a temperature adjustment module to adjust the temperature inside the box body, the biological tissue can be continuously in a low-temperature environment, avoiding poor preservation effects caused by repeated refrigeration of the biological tissue. Description of the Drawings

[0017] Figure 1 It is a structural diagram of the incubator provided in Embodiment 1 of the present utility model;

[0018] Figure 2 It is an internal structural diagram of the incubator provided in Embodiment 1 of the present utility model;

[0019] Figure 3 It is a structural diagram of the air outlet unit in the incubator provided in Embodiment 1 of the present utility model;

[0020] Figure 4 It is a structural diagram of the air baffle in the incubator provided in Embodiment 1 of the present utility model;

[0021] Figure 5 It is a structural diagram of the automatic liquid nitrogen tank provided in Embodiment 2 of the present utility model.

[0022] In the figure, 1 is an incubator, 11 is a box body, 111 is an air outlet, 12 is a box door, 121 is an air baffle, 13 is a temperature adjustment module, 131 is a temperature measurement unit, 132 is a temperature adjustment unit, 1321 is a pipeline, 1322 is a nozzle, 14 is a control module, 15 is an air outlet module, 151 is a flow guide plate, 152 is an exhaust fan, and 2 is a tank body. Detailed implementation mode

[0023] In order to make the purpose, technical solution and advantages of the present utility model more clear and understandable, the following further details the present utility model in conjunction with specific embodiments. It should be understood that the specific embodiments described herein are only used to explain the present utility model and are not used to limit the present utility model.

[0024] In the description of the present utility model, it should be clear that the terms "vertical", "horizontal", "longitudinal", "front", "rear", "left", "right", "upper", "lower", "horizontal", etc. indicate the orientation or position relationship based on the orientation or position relationship shown in the drawings. This is only for the convenience of describing the present utility model and does not mean that the indicated device or element must have a specific orientation or position. Therefore, it should not be construed as a limitation to the present utility model. In the description of the present utility model, it should be noted that unless otherwise clearly specified and limited, the terms "installation", "connection", and "connection" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be directly connected or indirectly connected through an intermediate medium. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0025] Embodiment 1

[0026] An incubator provided in this embodiment is used to be set on an automatic liquid nitrogen tank. As shown in Figure 1 、 Figure 2 , the incubator 1 includes a box body 11, a box door 12 and a temperature adjustment module 13. The box door 12 is movably provided on the box body 11, and the temperature adjustment module 13 is provided inside the box body 11. During use, the temperature inside the box body 11 is adjusted by adjusting the temperature adjustment module 13 to be at a low temperature, and the biological tissue taken out from the automatic liquid nitrogen tank is placed inside the box body 11 of the incubator 1 for preservation.

[0027] Based on the above structure, the incubator 1 is set at the outlet of the automatic liquid nitrogen tank, and the temperature inside the box body 11 is adjusted by the temperature adjustment module 13, so that the biological tissue leaving the automatic liquid nitrogen tank is not directly exposed to the normal temperature environment, but continuously remains in a low temperature environment, which can avoid the poor preservation effect caused by the repeated refrigeration of biological components.

[0028] In some embodiments of the present application, the incubator 1 further includes a control module 14, and the temperature adjustment module 13 is connected to the control module 14.

[0029] In this embodiment, the control module 14 is used to automatically control the temperature adjustment module 13, improving the convenience and accuracy of temperature adjustment in the box body 11.

[0030] In some embodiments of the present application, the temperature adjustment module 13 includes a temperature measurement unit 131 and a temperature adjustment unit 132, and both the temperature measurement unit 131 and the temperature adjustment unit 132 are connected to the control module 14.

[0031] In this embodiment, the temperature in the box body 11 is detected in real time by the temperature measurement unit 131, and the detection result is sent to the control module 14. The control module 14 controls the opening and closing of the temperature adjustment unit 132 according to the detection result.

[0032] Specifically, a temperature threshold of the box body 11 is set on the control module 14. If the temperature in the box body 11 detected by the temperature measurement unit 132 is higher than the temperature threshold, the control module 14 sends a signal to control the opening of the temperature adjustment unit 132, and vice versa to control the closing of the temperature adjustment unit 132.

[0033] In some embodiments of the present application, the temperature measurement unit 131 includes at least one temperature sensor. At least one of the temperature sensors is disposed in the box body 11, and at least one of the temperature sensors is electrically connected to the control module 14.

[0034] Specifically, three temperature sensors are provided, which are respectively located beside the inner door 12 of the box body 11, the upper inner side of the box body 11, and the lower inner side of the box body 11, and are respectively used to detect the temperatures at the upper part, the lower part and the door 12 of the box body 11 to ensure the accuracy of temperature measurement.

[0035] In some embodiments of the present application, the temperature adjustment unit 132 includes a pipeline 1321, a liquid inlet valve and at least one nozzle 1322. The pipeline 1321 is disposed inside the box body 11, and both the liquid inlet valve and the nozzle 1322 are disposed on the pipeline 1321, and the liquid inlet valve is electrically connected to the control module 14.

[0036] The pipeline 1321 is disposed at the top inside the box body 11 for transporting liquid nitrogen, and the liquid nitrogen is sprayed into the box body 11 through the nozzle 1322. The liquid nitrogen quickly vaporizes in the box body 11 to lower the temperature inside the box body 11.

[0037] Specifically, the pipeline 1321 is in a circular ring structure or a frame structure, at least one nozzle 1322 is uniformly disposed on the pipeline 1321, and the control end of the liquid inlet valve is electrically connected to the control module 14 to control whether the liquid nitrogen is sprayed or not.

[0038] In some embodiments of the present application, a liquid outlet is provided at the bottom of the box body 11 to facilitate the discharge of small water droplets condensed by the cold air out of the box body 11 .

[0039] Specifically, the liquid outlet is arranged on the outer peripheral edge of the bottom of the box body 11 .

[0040] like Figure 3 As shown, in some embodiments of the present application, the thermal insulation box 1 further includes an air outlet module 15 disposed on the top of the box body 11 for discharging excess nitrogen in the box body 11 .

[0041] In some embodiments of the present application, the top of the box body 11 is provided with an air outlet 111 which passes through it, and the air outlet module 15 includes a guide plate 151 and an exhaust fan 152, and the exhaust fan 152 and the guide plate 151 are located on both sides of the air outlet 111.

[0042] In this embodiment, the excess nitrogen in the box 11 is discharged from the air outlet 111, and the discharged nitrogen is gathered by the guide plate 151 to prevent the nitrogen from escaping everywhere. The exhaust fan 152 is used to collect the discharged nitrogen and recycle it.

[0043] like Figure 4 As shown, in some embodiments of the present application, a slidable air baffle 121 is provided on the box body 11 , and the air baffle 121 is located at the box door 12 .

[0044] This embodiment can adjust the size of the box door 12 by providing an air baffle 121 to prevent excessive contact between the gas in the box body 11 and the air, thereby ensuring the temperature regulation effect in the box body 11.

[0045] Example 2

[0046] An automatic liquid nitrogen tank, the structure is as follows Figure 5 As shown, it includes a tank body 2 and the thermal insulation box 1 described in Example 1, and the interior of the tank body 2 is isolated from the interior of the thermal insulation box 1 by a plug cover.

[0047] The method for using the automatic liquid nitrogen tank with the incubator 1 provided in this embodiment is as follows:

[0048] Before use, connect the incubator 1 to the outlet of the tank body 2, and isolate the interior of the tank body 2 and the interior of the incubator 1 through a plug cover. The interior of the tank body 2 is always in a low-temperature environment, and biological tissues are stored in the tank body 2. When taking or placing biological tissues, open the box door 12 and the plug cover, move the cryopreservation rack storing the biological tissues from the tank body 2 into the box body 11, fasten the plug cover to seal the tank body 2 to continuously maintain a low temperature, and slide the air baffle 121 to leave an appropriate size for the box door 12 to facilitate the user to take or place biological tissues. At the same time, the temperature measurement unit 131 in the temperature adjustment module 13 detects the temperature inside the box body 11 in real time, and sends the detection result to the control module 14. The control module 14 controls the closing and opening of the liquid inlet valve according to the detection result, so as to timely spray liquid nitrogen into the box body 11 through the pipeline 1321 and the nozzle 1322 to keep the box body 11 in a low-temperature state continuously and improve the preservation effect of biological tissues.

[0049] As described above, only the preferred specific implementation manner of the present utility model is given, but the protection scope of the present utility model is not limited thereto. Any changes or substitutions that can be easily thought of by those skilled in the art within the technical scope disclosed by the present utility model should be covered by the protection scope of the present utility model. Therefore, the protection scope of the present utility model should be subject to the protection scope of the claims.

Claims

1. An insulated box, used to be installed on an automatic liquid nitrogen tank, characterized in that: The incubator (1) comprises a box body (11), a box door (12) and a temperature regulating module (13); the box door (12) is arranged on the box body (11) in an openable and closable manner, and the temperature regulating module (13) is arranged in the box body (11); when in use, the temperature in the box body (11) is kept at a low temperature by adjusting the temperature regulating module (13), and the biological tissue taken out from the automatic liquid nitrogen tank is placed in the box body (11) of the incubator (1) for storage.

2. The thermal insulation box according to claim 1, characterized in that: The thermal insulation box (1) also includes a control module (14), and the temperature adjustment module (13) is connected to the control module (14).

3. The thermal insulation box according to claim 2, characterized in that: The temperature adjustment module (13) comprises a temperature measuring unit (131) and a temperature adjustment unit (132), and both the temperature measuring unit (131) and the temperature adjustment unit (132) are connected to the control module (14).

4. The thermal insulation box according to claim 3, characterized in that: The temperature measuring unit (131) comprises at least one temperature sensor, at least one of the temperature sensors is arranged in the box (11), and at least one of the temperature sensors is electrically connected to the control module (14).

5. The thermal insulation box according to claim 4, characterized in that: The temperature adjustment unit (132) comprises a pipeline (1321), a liquid inlet valve and at least one nozzle (1322); the pipeline (1321) is arranged inside the box (11); the liquid inlet valve and the nozzle (1322) are both arranged on the pipeline (1321); and the liquid inlet valve is electrically connected to the control module (14).

6. The thermal insulation box according to any one of claims 1 to 5, characterized in that: The bottom of the box body (11) is provided with a liquid outlet.

7. The thermal insulation box according to any one of claims 1 to 5, characterized in that: The heat preservation box (1) also includes an air outlet module (15) arranged on the top of the box body (11).

8. The thermal insulation box according to claim 7, characterized in that: The top of the box body (11) is provided with an air outlet (111) which is in communication therewith; the air outlet module (15) comprises a guide plate (151) and an exhaust fan (152); the exhaust fan (152) and the guide plate (151) are located on both sides of the air outlet (111).

9. The thermal insulation box according to any one of claims 1 to 5, characterized in that: A slidable air baffle plate (121) is provided on the box body (11), and the air baffle plate (121) is located at the box door (12).

10. An automatic liquid nitrogen tank, characterized in that: It comprises a tank body (2) and an insulation box (1) as claimed in any one of claims 1 to 9, wherein the interior of the tank body (2) is isolated from the interior of the insulation box (1) by a plug cover.

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