Full-automatic cell immunolabeling instrument

Abstract

The utility model relates to the technical field of medical equipment, in particular to a full-automatic cell immunolabeling instrument which comprises a cover plate and a replacement assembly, the replacement assembly is arranged at the top of the cover plate and comprises a test tube placing plate, the test tube placing plate is movably connected to the top of the cover plate, a placing groove is formed in the top of the test tube placing plate, and the test tube placing plate is arranged in the placing groove. And a liquid containing test tube is arranged in the containing groove, fixing plates are fixedly connected to the two sides of the test tube containing plate, first threaded holes are formed in the tops of the fixing plates, and threaded rods are in threaded connection with inner cavities of the first threaded holes. According to the full-automatic cell immunolabeling instrument, by installing the replacement assembly, after all reagents are added, a worker rotates an adjusting knob to screw out a threaded rod from the interiors of a first threaded hole and a second threaded hole, then a lifting handle lifts a test tube placement plate from a cover plate, different reagents are replaced, the worker does not need to take down all test tubes, and the operation is convenient. Therefore, the marking efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of medical device equipment, in particular to a full-automatic cell immune labeling instrument. Background Art

[0002] Cell immune labeling is an experimental technique for studying the function of the immune system at the cellular level. A cell immune labeling instrument usually refers to a flow cytometer, which is an instrument used to detect and analyze single cells. It can quickly and accurately measure the size, shape of cells and the expression of specific antigens. The flow cytometer combines hydrodynamic focusing technology and laser optical detection technology and can analyze thousands of cells at the single-cell level.

[0003] When the existing cell immune labeling instrument is performing labeling, after all the reagents in the test tube are added, the staff needs to remove all the test tubes on the test tube rack and then place test tubes filled with different reagents, thus reducing the labeling efficiency. Content of the Utility Model

[0004] The purpose of the utility model is to provide a full-automatic cell immune labeling instrument to solve the problem that when the existing cell immune labeling instrument is performing labeling, the staff needs to remove all the test tubes on the test tube rack as mentioned in the above background art. To achieve the above purpose, the utility model provides the following technical scheme: a full-automatic cell immune labeling instrument, including a cover plate and a replacement component. The replacement component is arranged on the top of the cover plate. The replacement component includes a test tube placement plate, the test tube placement plate is movably connected to the top of the cover plate. A placement groove is opened on the top of the test tube placement plate, and a liquid-containing test tube is arranged inside the placement groove. Fixed plates are fixedly connected to both sides of the test tube placement plate, a first threaded hole is opened on the top of the fixed plate, a threaded rod is threadedly connected to the inner cavity of the first threaded hole, an adjusting knob is fixedly connected to the top of the threaded rod, a second threaded hole is opened on the top of the cover plate, a handle is fixedly connected to one side of the test tube placement plate, and an adjusting component is arranged at the bottom of the cover plate.

[0005] Further preferably, the adjusting component includes a box body, the box body is arranged at the bottom of the cover plate, a first rotating motor is arranged on one side inside the box body, a lead screw is fixedly connected to the driving end of the first rotating motor, a pushing tube is arranged on the side surface of the lead screw, a support rod is fixedly connected to the top of the pushing tube, and a load-bearing platform is fixedly connected to the top of the support rod.

[0006] Further preferably, a servo motor is fixedly connected to the top of the load-bearing platform. The driving end of the servo motor is fixedly connected to a first connecting shaft. The top of the first connecting shaft is fixedly connected to a syringe cap. A liquid injection syringe is arranged at the bottom of the syringe cap. A rotating assembly is arranged at the bottom inside the box body. By installing the rotating assembly, the staff can turn on the second rotating motor to drive the second connecting shaft to rotate. The second connecting shaft drives the first bevel gear and the second bevel gear. The second bevel gear drives the rotating rod to control the slide clamp to move directly below the liquid adding hole. The reagent is sprayed on the slide clamp through the liquid adding pump for marking.

[0007] Further preferably, the rotating assembly includes a second rotating motor, which is fixedly connected to the bottom inside the box body. The driving end of the second rotating motor is fixedly connected to a second connecting shaft. The top of the second connecting shaft is fixedly connected to a first bevel gear. The other side of the first bevel gear is meshed with a second bevel gear. A rotating rod is fixedly connected inside the second bevel gear. The top of the rotating rod is fixedly connected to a tray. A slide clamp is arranged on the top of the tray. A liquid adding hole is formed in the top of the cover plate.

[0008] Further preferably, a controller is fixedly connected to the top of the box body. A frame is fixedly connected to the top of the box body. A liquid adding pump is arranged on one side of the frame.

[0009] Further preferably, a hidden groove is formed in one side of the box body. A first liquid storage bottle is arranged at the bottom of the inner wall of the hidden groove. A second liquid storage bottle is arranged on the other side of the first liquid storage bottle.

[0010] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0011] In the present utility model, by installing the replacement component, after all the reagents are added, the staff rotates the adjustment knob to screw the threaded rod out of the first threaded hole and the second threaded hole, and then lifts the test tube placement plate from the cover plate by the handle to replace different reagents, without the staff removing all the test tubes, thereby improving the marking efficiency.

[0012] In the present utility model, by installing the adjustment component, turn on the first rotating motor to drive the lead screw to rotate. The lead screw drives the load-bearing platform to lift and lower through the push tube. Then turn on the servo motor to drive the first connecting shaft to rotate. The first connecting shaft moves the liquid injection syringe to directly above the liquid-containing test tube through the syringe cap. Then control the load-bearing platform to lift and lower through the first rotating motor to insert the liquid injection syringe into the liquid-containing test tube, and the reagent in the liquid-containing test tube can be extracted. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 is a schematic three-dimensional structure diagram of the present utility model;

[0014] Figure 2Schematic diagram of the three-dimensional unfolded structure of the present utility model;

[0015] Figure 3 For the present utility model Figure 2 Enlarged structure diagram at position A in it;

[0016] Figure 4 Partial three-dimensional detailed structure diagram of the present utility model;

[0017] Figure 5 For the present utility model Figure 4 Enlarged structure diagram at position B in it;

[0018] Figure 6 For the present utility model Figure 4 Enlarged structure diagram at position C in it.

[0019] In the figure: 1. Cover plate; 2. Replacement component; 201. Test tube placement plate; 202. Placement groove; 203. Liquid-containing test tube; 204. Fixed plate; 205. First threaded hole; 206. Threaded rod; 207. Adjusting knob; 208. Second threaded hole; 209. Handle; 3. Adjusting component; 301. Box body; 302. First rotating motor; 303. Lead screw; 304. Pushing tube; 305. Support rod; 306. Load-bearing platform; 307. Servo motor; 308. First connecting shaft; 309. Syringe needle cap; 310. Liquid injection syringe; 4. Rotating component; 401. Second rotating motor; 402. Second connecting shaft; 403. First bevel gear; 404. Second bevel gear; 405. Rotating rod; 406. Tray; 407. Slide glass clamp; 408. Liquid addition hole; 5. Controller; 6. Frame; 7. Liquid addition pump; 8. Hidden groove; 9. First liquid storage bottle; 10. Second liquid storage bottle. Specific implementation manners

[0020] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0021] Please refer to Figures 1-6, the present utility model provides a technical solution: a full-automatic cell immunolabeling instrument, including a cover plate 1 and a replacement component 2. The replacement component 2 is arranged on the top of the cover plate 1. The replacement component 2 includes a test tube placement plate 201. The test tube placement plate 201 is movably connected to the top of the cover plate 1. A placement groove 202 is provided on the top of the test tube placement plate 201. A liquid-containing test tube 203 is arranged inside the placement groove 202. Fixed plates 204 are fixedly connected to both sides of the test tube placement plate 201. A first threaded hole 205 is provided on the top of the fixed plate 204. A threaded rod 206 is threadedly connected to the inner cavity of the first threaded hole 205. An adjustment knob 207 is fixedly connected to the top of the threaded rod 206. A second threaded hole 208 is provided on the top of the cover plate 1. A handle 209 is fixedly connected to one side of the test tube placement plate 201. An adjustment component 3 is arranged at the bottom of the cover plate 1.

[0022] In this embodiment, as Figure 1 , Figure 2 , Figure 4 and Figure 5 shown, the adjustment component 3 includes a box body 301. The box body 301 is arranged at the bottom of the cover plate 1. A first rotary motor 302 is arranged on one side inside the box body 301. A lead screw 303 is fixedly connected to the transmission end of the first rotary motor 302. A push tube 304 is arranged on the side surface of the lead screw 303. A support rod 305 is fixedly connected to the top of the push tube 304. A load-bearing platform 306 is fixedly connected to the top of the support rod 305.

[0023] In this embodiment, as Figure 1 , Figure 2 , Figure 4 and Figure 5 shown, a servo motor 307 is fixedly connected to the top of the load-bearing platform 306. A first connecting shaft 308 is fixedly connected to the transmission end of the servo motor 307. A syringe needle cap 309 is fixedly connected to the top of the first connecting shaft 308. An injection syringe needle 310 is arranged at the bottom of the syringe needle cap 309. A rotation component 4 is arranged at the bottom inside the box body 301. Then, the staff turns on the first rotary motor 302 through the controller 5. The first rotary motor 302 drives the lead screw 303 to rotate. The lead screw 303 pushes the load-bearing platform 306 to rise and fall through the push tube 304. Then, the servo motor 307 is turned on. The servo motor 307 drives the first connecting shaft 308 to rotate. The first connecting shaft 308 moves the injection syringe needle 310 to directly above the liquid-containing test tube 203 through the syringe needle cap 309. Then, the load-bearing platform 306 is controlled to rise and fall through the first rotary motor 302, and the injection syringe needle 310 is inserted into the liquid-containing test tube 203 to extract the reagent. After the extraction is completed, the injection syringe needle 310 is controlled to move to directly above the liquid addition hole 408.

[0024] In this embodiment, as Figure 1 , Figure 2 , Figure 4 and Figure 6As shown in the figure, the rotating assembly 4 includes a second rotating motor 401. The second rotating motor 401 is fixedly connected to the bottom inside the box body 301. The driving end of the second rotating motor 401 is fixedly connected to a second connecting shaft 402. The top of the second connecting shaft 402 is fixedly connected to a first bevel gear 403. The other side of the first bevel gear 403 is meshed with a second bevel gear 404. The inside of the second bevel gear 404 is fixedly connected to a rotating rod 405. The top of the rotating rod 405 is fixedly connected to a tray 406. A slide clamp 407 is arranged on the top of the tray 406. A liquid adding hole 408 is opened at the top of the cover plate 1. Immediately afterwards, the staff turns on the second rotating motor 401 to drive the second connecting shaft 402 to rotate. The second connecting shaft 402 drives the first bevel gear 403 and the second bevel gear 404. The second bevel gear 404 drives the rotating rod 405 to control the slide clamp 407 to move directly below the liquid adding hole 408. The reagent is sprayed on the slide clamp 407 through the liquid adding pump 7 for marking.

[0025] In this embodiment, as Figure 1 and Figure 2 shown, a controller 5 is fixedly connected to the top of the box body 301. A frame 6 is fixedly connected to the top of the box body 301. A liquid adding pump 7 is arranged on one side of the frame 6.

[0026] In this embodiment, as Figure 1 and Figure 2 shown, a hidden groove 8 is opened on one side of the box body 301. A first liquid storage bottle 9 is arranged at the bottom of the inner wall of the hidden groove 8. A second liquid storage bottle 10 is arranged on the other side of the first liquid storage bottle 9.

[0027] The usage method and advantages of the present utility model: For this fully automatic cell immune labeling instrument, during use, the working process is as follows:

[0028] As Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 、 Figure 5 and Figure 6As shown, when using this device, the staff places the test tube placement plate 201 on the cover plate 1, aligns the first threaded hole 205 on the fixing plate 204 with the second threaded hole 208 on the cover plate 1, and then rotates the adjustment knob 207. The adjustment knob 207 drives the threaded rod 206, screws the threaded rod 206 into the first threaded hole 205 and the second threaded hole 208 to install the test tube placement plate 201. Then, the staff turns on the first rotating motor 302 through the controller 5. The first rotating motor 302 drives the lead screw 303 to rotate. The lead screw 303 drives the load-bearing platform 306 to lift and lower through the push tube 304. Then, the servo motor 307 is turned on. The servo motor 307 drives the first connecting shaft 308 to rotate. The first connecting shaft 308 moves the liquid injection syringe 310 to directly above the liquid-containing test tube 203 through the syringe cap 309. Then, the load-bearing platform 306 is lifted and lowered by controlling the first rotating motor 302 to insert the liquid injection syringe 310 into the liquid-containing test tube 203 to extract the reagent. After the extraction is completed, the liquid injection syringe 310 is controlled to move directly above the liquid addition hole 408. Immediately afterwards, the staff turns on the second rotating motor 401 to drive the second connecting shaft 402 to rotate. The second connecting shaft 402 drives the first bevel gear 403 and the second bevel gear 404. The second bevel gear 404 drives the rotating rod 405 to control the slide clamp 407 to move directly below the liquid addition hole 408. The reagent is sprayed on the slide clamp 407 through the liquid addition pump 7 for marking. When all the reagents are added, the staff rotates the adjustment knob 207. The adjustment knob 207 drives the threaded rod 206 to screw the threaded rod 206 out of the first threaded hole 205 and the second threaded hole 208. Then, the handle 209 is used to lift the test tube placement plate 201 from the cover plate 1 to replace different reagents.

[0029] The above shows and describes the basic principles, main features and advantages of the present invention. Technical staff in this industry should understand that the present invention is not limited by the above embodiments. The above embodiments and the descriptions in the specification are only preferred examples of the present invention and are not used to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed. The scope of protection claimed by the present invention is defined by the appended claims and their equivalents.

Claims

1. A fully automatic cell immune labeling instrument, comprising a cover plate (1) and a replacement component (2), characterized in that: The replacement component (2) is arranged on the top of the cover plate (1), and the replacement component (2) comprises a test tube placement plate (201), the test tube placement plate (201) is movably connected to the top of the cover plate (1), a placement groove (202) is provided on the top of the test tube placement plate (201), a liquid-containing test tube (203) is provided inside the placement groove (202), fixing plates (204) are fixedly connected to both sides of the test tube placement plate (201), a threaded hole (205) is provided on the top of the fixing plate (204), a threaded rod (206) is threadedly connected to the inner cavity of the threaded hole (205), an adjustment knob (207) is fixedly connected to the top of the threaded rod (206), a threaded hole (208) is provided on the top of the cover plate (1), a handle (209) is fixedly connected to one side of the test tube placement plate (201), and an adjustment component (3) is provided at the bottom of the cover plate (1).

2. The fully automatic cell immune labeling instrument according to claim 1, characterized in that: The adjustment assembly (3) comprises a box (301), wherein the box (301) is arranged at the bottom of the cover plate (1), and a rotating motor (302) is arranged on one side inside the box (301), a screw rod (303) is fixedly connected to the transmission end of the rotating motor (302), a push tube (304) is arranged on the side surface of the screw rod (303), a support rod (305) is fixedly connected to the top of the push tube (304), and a load-bearing platform (306) is fixedly connected to the top of the support rod (305).

3. The fully automatic cell immune labeling instrument according to claim 2, characterized in that: A servo motor (307) is fixedly connected to the top of the load-bearing platform (306), a connecting shaft (308) is fixedly connected to the driving end of the servo motor (307), a syringe cover (309) is fixedly connected to the top of the connecting shaft (308), an injection syringe (310) is arranged at the bottom of the syringe cover (309), and a rotating assembly (4) is arranged at the bottom of the box body (301).

4. The fully automatic cell immune labeling instrument according to claim 3, characterized in that: The rotating assembly (4) comprises a second rotating motor (401), wherein the second rotating motor (401) is fixedly connected to the bottom of the housing (301), the transmission end of the second rotating motor (401) is fixedly connected to a second connecting shaft (402), the top of the second connecting shaft (402) is fixedly connected to a first bevel gear (403), the other side of the first bevel gear (403) is meshingly connected to a second bevel gear (404), the interior of the second bevel gear (404) is fixedly connected to a rotating rod (405), the top of the rotating rod (405) is fixedly connected to a tray (406), the top of the tray (406) is provided with a glass slide clamp (407), and the top of the cover plate (1) is provided with a liquid adding hole (408).

5. The fully automatic cell immune labeling instrument according to claim 2, characterized in that: A controller (5) is fixedly connected to the top of the box (301), a frame (6) is fixedly connected to the top of the box (301), and a liquid adding pump (7) is provided on one side of the frame (6).

6. The fully automatic cell immune labeling instrument according to claim 2, characterized in that: A hidden groove (8) is provided on one side of the box body (301), a first liquid storage bottle (9) is provided at the bottom of the inner wall of the hidden groove (8), and a second liquid storage bottle (10) is provided on the other side of the first liquid storage bottle (9).

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