Rapid detection device for liquid sample

Abstract

The utility model discloses a rapid detection device. The device comprises an insertion plate, a detection element, a running plate auxiliary part and a covering layer. A detection area and a sample cavity are arranged on the detection surface of the insertion plate; the detection area is provided with a clamping groove or a plurality of clamping grooves arranged side by side. And the end part of each clamping groove is communicated with the sample cavity. The detection element is installed in the clamping groove. A running plate auxiliary part for absorbing liquid is arranged in the sample cavity. According to the utility model, the running board auxiliary parts covering the bottoms of all the detection elements on the same detection surface are arranged on the plugboard; the running board auxiliary part adopting the glass fiber sheet, the polyester film or the absorbent paper can enable the sample liquid to quickly and uniformly reach all the detection elements, so that each detection element is promoted to quickly and synchronously run. On the basis, the detection time can be effectively shortened, the detection result can be obtained within one minute, high accuracy is guaranteed, and meanwhile the detection efficiency is greatly improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of sample detection, and particularly relates to a rapid detection device for liquid samples. Background Art

[0002] To monitor drug abuse and combat illegal drug economic and trade activities, a rapid and simple on-site detection device is needed.

[0003] Existing detection devices are based on immunoassay, chromatography, mass spectrometry, etc. Although these devices and technologies can also perform on-site detection, the detection efficiency is far from sufficient. Currently, the most widely used detection devices still require more than 3 minutes to obtain detection results. Summary of the Invention

[0004] To make up for the deficiencies of the existing technology, the utility model provides a rapid detection device for detecting liquid samples.

[0005] A rapid detection device for detecting liquid samples provided by the utility model includes an insertion board, a detection element, a running board auxiliary, and a covering layer. One or more detection surfaces are provided on the insertion board. A detection area and a sample cavity are provided on the detection surface of the insertion board; a card slot or multiple card slots arranged side by side are provided on the detection area. The ends of each card slot communicate with the sample cavity. The detection element is installed in the card slot. The sample addition area at the bottom of the detection element is located in the sample cavity. A running board auxiliary for absorbing liquid is provided in the sample cavity. The running board auxiliary covers the sample addition areas at the bottoms of all detection elements on the same detection surface. The covering layer is attached to the detection surface of the insertion board; a sample addition window aligned with the running board auxiliary is provided on the covering layer.

[0006] Preferably, the running board auxiliary is made of a glass fiber sheet, a polyester film, or blotting paper.

[0007] Preferably, only one side of the insertion board is the detection surface.

[0008] Preferably, both sides of the insertion board are detection surfaces.

[0009] Preferably, the card slots on the two detection surfaces of the insertion board are respectively aligned; n sample circulation holes are provided at the bottom of the insertion board; n is the number of card slots on a single detection surface; the n sample circulation holes are respectively aligned with the ends of the n card slots on the same detection surface. The sample cavities on the two detection surfaces of the insertion board communicate through the sample circulation holes.

[0010] Preferably, there is a partial overlapping area between the sample circulation holes and the running board auxiliary.

[0011] Preferably, staples for fixing the detection element are provided on both side walls of each card slot.

[0012] Preferably, any two adjacent card slots on the same detection surface are separated by ribs. An opening that connects two adjacent card slots is provided on the rib. Further preferably, the position of the opening is aligned with the marking pad area on the detection element.

[0013] Preferably, groove structures are provided on the outer side walls of the two card slots closest to the two side edges of the plug board. The two groove structures are aligned with the openings on the ribs.

[0014] Preferably, a channel structure is provided in some or all of the ribs. The length direction of the channel structure is parallel to the length direction of the card slot, and the bottom end is communicated with the sample chamber.

[0015] Preferably, a residual sample storage chamber located above the detection area is provided on all or part of the detection surface of the plug board. The top end of the channel structure is communicated with the residual sample storage chamber.

[0016] Preferably, a protective cover is further included. A slot structure corresponding to the bottom of the plug board is provided on the protective cover. In the initial state, the bottom of the plug board is inserted into the slot structure on the protective cover.

[0017] Preferably, one or more reinforcing structures are provided on the inner side wall of the protective cover.

[0018] The beneficial effects of the present utility model are as follows:

[0019] 1. The present utility model provides a running board auxiliary on the plug board that covers the bottoms of all detection elements on the same detection surface; the running board auxiliary made of fiberglass sheet, polyester film or blotting paper can enable the sample liquid to reach all detection elements quickly and evenly, promoting the running board of each detection element quickly and synchronously. Based on this, the present utility model can effectively shorten the detection time, obtain the detection result in 1 minute, ensure high accuracy and greatly improve the detection efficiency.

[0020] 2. The present utility model provides longitudinal and transverse exhaust structures on the detection surface of the plug board, and the inside of each card slot can be effectively exhausted, avoiding the situation that the running board effect is affected due to the inability to release the internal pressure of the card slot.

[0021] 3. The present utility model installs detection elements and running board auxiliaries on both side surfaces of the plug board, increasing the number of types of detection targets of the detection device. Description of the Drawings

[0022] Figure 1 is an exploded schematic diagram of Embodiment 1 of the present utility model;

[0023] Figure 2 is a front view of the plug board in Embodiment 1 of the present utility model;

[0024] Figure 3Schematic diagram of the insertion plate for installing the detection element in Embodiment 1 of the present utility model;

[0025] Figure 4 Internal schematic diagram of the protective cover in Embodiment 1 of the present utility model;

[0026] Figure 5 Explosion schematic diagram of Embodiment 2 of the present utility model.

[0027] Reference numerals: 1, insertion plate; 1-1, card slot; 1-2, staple; 1-3, rib; 1-4, sample cavity; 1-5, sample flow hole; 1-6, residual sample storage cavity; 1-7, channel structure; 1-8, opening; 1-9, partition structure; 1-10, flange structure; 2, protective cover; 2-1, reinforcement structure; 3, detection element; 4, running plate auxiliary; 5, covering layer; 5-1, sample addition window. Detailed implementation manners

[0028] The following describes in detail the structure involved in the present utility model in conjunction with the embodiments. The embodiments are only the preferred implementation manners of the present utility model and do not limit the present utility model.

[0029] Embodiment 1

[0030] As Figure 1 shown, a rapid liquid sample detection device includes an insertion plate 1, a covering layer 5, a protective cover 2 and a detection element 3. The insertion plate 1 is a rigid structure, and both of its two side surfaces are detection surfaces. The protective cover 2 is provided with a slot structure corresponding to the bottom of the insertion plate 1. The bottom of the insertion plate 1 is inserted into the slot structure on the protective cover 2.

[0031] The detection surface of the insertion plate 1 is divided into a top area, a detection area and a sample addition area arranged in sequence from top to bottom. Six card slots 1-1 are arranged at intervals along the width direction of the insertion plate 1 in the detection area; Staples 1-2 for fixing the detection element 3 are provided on both side walls of each card slot 1-1. Adjacent two card slots 1-1 are separated by ribs 1-3. The card slot 1-1 is used to accommodate the detection element 3. In this embodiment, the detection element 3 adopts a reagent strip. The outer surface of the rib 1-3 is flush with the edge of the detection surface. An inwardly concave sample cavity 1-4 is provided in the sample addition area on the detection surface. The end (i.e., the bottom end) of each card slot 1-1 communicates with the top of the sample cavity 1-4. The sample addition area at the bottom end of the detection element 3 extends into the sample cavity 1-4.

[0032] A sample chamber 1-4 is provided with a running plate auxiliary member 4. The running plate auxiliary member 4 covers the sampling areas at the bottoms of all the detection elements 3 on the same detection surface. The running plate auxiliary member 4 is used to quickly absorb the sample, assist in running the plate, ensure high accuracy and greatly improve the detection efficiency. In this embodiment, the running plate auxiliary member 4 is made of a glass fiber sheet. In some other embodiments, the running plate auxiliary member 4 is made of a polyester film or absorbent paper.

[0033] Each detection surface of the plug board 1 corresponds to a covering layer 5. Two covering layers 5 are respectively attached to the two detection surfaces of the plug board 1; the covering layer 5 is used to prevent the detection elements 3 from shifting or falling off during transportation and detection, assist in running the plate and ensure the detection effectiveness. In this embodiment, the covering layer 5 is a panel adhesive.

[0034] The plug board 1 can be made of a transparent material or a non-transparent material; the covering layer 5 can be made of a transparent material or a non-transparent material; and the transparent or non-transparent plug board 1 and the covering layer 5 can be arbitrarily combined. The covering layer 5 can be made of a flexible material or a rigid material.

[0035] Six observation window groups corresponding to the six card slots 1-1 are formed on the covering layer 5; each observation window group includes two observation windows respectively aligned with the detected object name identification area and the detected object detection result display area on the detection element 3. A sampling window 5-1 aligned with the running plate auxiliary member 4 is also formed on the covering layer 5.

[0036] Six sample circulation holes 1-5 are formed at the bottom of the plug board 1 in the sampling area; the six sample circulation holes 1-5 are respectively aligned with the bottoms of the six card slots 1-1 on the same detection surface. The six sample circulation holes 1-5 connect the sample chambers 1-4 at the bottoms of the two detection surfaces of the plug board 1, thereby improving the uniformity of running the plate.

[0037] As a non-essential preferred solution, there is a partial overlapping area between the sample circulation holes 1-5 and the running plate auxiliary member 4.

[0038] In some embodiments, a residual sample storage chamber 1-6 is provided in the top area of the detection surface of the plug board 1. According to actual requirements, the residual sample storage chamber 1-6 can be provided only on one of the detection surfaces, or on both detection surfaces.

[0039] In some embodiments, openings 1-8 are provided on all the ribs 1-3. The two ends of the opening 1-8 are respectively communicated with two adjacent card slots 1-1. The position of the opening 1-8 is aligned with the marked pad area on the detection element 3. Groove structures are provided on the outer sidewalls of the two card slots 1-1 closest to the two side edges of the plug board 1. The two groove structures are aligned with the openings 1-8 on the ribs 1-3 and jointly form a lateral exhaust structure when the adhesive covering layer 5 is pasted. In addition, the opening 1-8 also functions to block the upward flow of the liquid sample along the gap formed by the sidewall of the card slot 1-1 and the side of the detection element 3 under capillary action.

[0040] In some embodiments, a channel structure 1-7 is provided in the strip-shaped rib 1-3. The two ends of the channel structure 1-7 are respectively communicated with the residual sample storage cavity 1-6 in the top area and the sample cavity 1-4 in the sample adding area. On the one hand, the channel structure 1-7 serves as a longitudinal exhaust structure when the adhesive covering layer 5 is pasted, and on the other hand, it can absorb the excess sample liquid in the sample cavity 1-4 into the residual sample storage cavity 1-6 by capillary action. The channel structure 1-7 is truncated by the opening 1-8 on the rib 1-3.

[0041] In some embodiments, partition structures 1-9 are provided in some of the channel structures 1-7; further preferably, along the arrangement direction of each channel structure 1-7, the channel structures 1-7 provided with the partition structures 1-9 and the channel structures 1-7 not provided with the partition structures 1-9 are arranged alternately. The partition structure 1-9 helps to increase the pressure difference and improve the exhaust effect.

[0042] In some embodiments, a surrounding convex edge structure 1-10 is provided at the edge of the detection surface of the plug board 1; the covering layer 5 is arranged inside the convex edge structure 1-10. On the one hand, the convex edge structure 1-10 can prevent the middle part of the detection surface from directly contacting the support surface when the plug board 1 is placed flat, thus playing a role in protecting the covering layer 5 and the detection element 3; on the other hand, it can provide positioning when pasting the covering layer 5.

[0043] In some embodiments, the residual sample storage cavity 1-6 located in the top area of the detection surface of the plug board 1 is a single-hole or multi-hole structure.

[0044] In some embodiments, the hole structure of the residual sample storage cavity 1-6 is a neatly arranged honeycomb shape.

[0045] In some embodiments, the residual sample storage cavity 1-6 is located at the top end of the plug board 1 and can be formed by a single square or a multi-group square arrangement.

[0046] In some embodiments, the residual sample storage cavity 1-6 is located at the top end of the plug board 1, and the residual sample storage cavity 1-6 can communicate with one channel structure 1-7 or multiple channel structures 1-7.

[0047] In some embodiments, the rigid insertion plate 1 is integrally formed, and further, specifically by one-shot injection molding.

[0048] In some embodiments, the card slots 1-1 on the detection surface are one or more; the number of staples 1-2 on the card slots 1-1 can be multiple; each staple 1-2 is arranged at the upper end, middle, lower end or any other position on the side wall of the card slot 1-1, and can be either symmetric or asymmetric. The staple 1-2 helps prevent the liquid sample from flowing upward along the gap formed between the side wall of the card slot 1-1 and the side of the detection element 3. The size of the staple 1-2 is larger than the size that can form capillary flow to effectively prevent the liquid from passing through the gap between the side of the detection element 3 and the side wall of the card slot 1-1.

[0049] In some embodiments, the card slot 1-1 can accommodate one or more detection elements 3.

[0050] In some embodiments, the bottom surface of the sample cavity 1-4 is a flat structure or an inclined surface structure. Preferably, the bottom surface of the sample cavity 1-4 is a flat structure.

[0051] In some embodiments, the opening 1-8 on the rib 1-3 is formed by hollowing out the bottom of the rib 1-3. The opening 1-8 provided on the channel structure 1-7 can be located at any position on the channel structure 1-7.

[0052] In some embodiments, a reinforcement structure 2-1 is provided inside the inner cavity of the protective sleeve 2; on the one hand, the reinforcement structure 2-1 can improve the structural strength of the protective sleeve 2 to ensure that the protective sleeve 2 has a certain supporting effect; on the other hand, the four reinforcement structures 2-1 can jointly squeeze and clamp the bottom of the insertion plate 1, making the matching between the protective sleeve 2 and the insertion plate 1 assembled with the detection element 3 and the covering layer 5 more reliable, so that the protective sleeve 2 does not fall off.

[0053] In some embodiments, the reinforcement structure 2-1 inside the protective sleeve 2 is one or more.

[0054] In some embodiments, reinforcement structures 2-1 are provided at the four corners of the bottom of the inner cavity of the protective sleeve 2

[0055] In some embodiments, the reinforcement structure 2-1 inside the protective sleeve 2 is located on the left and right sides inside the protective sleeve 2.

[0056] In some embodiments, the reinforcement structure 2-1 inside the protective sleeve 2 is located on the front and back sides inside the protective sleeve 2.

[0057] In some embodiments, the reinforcement structure 2-1 inside the protective sleeve 2 is located on the left side inside the protective sleeve 2.

[0058] In some embodiments, the reinforcement structure 2-1 inside the protective sleeve 2 is located on the right side inside the protective sleeve 2.

[0059] In some embodiments, the reinforcement structure 2-1 inside the protective sleeve 2 is located at the inner front side of the protective sleeve 2.

[0060] In some embodiments, the reinforcement structure 2-1 inside the protective sleeve 2 is located at the inner rear side of the protective sleeve 2.

[0061] The working principle of this embodiment is as follows:

[0062] Separate the protective sleeve 2 from the insertion plate 1; insert the bottom of the insertion plate 1 into the sample to be measured, so that the running plate auxiliary member 4 contacts the sample to be measured; hold for a period of time, and then take it out; the sample to be measured entering the sample chamber 1-4 contacts each detection element 3 quickly and fully under the guidance of the running plate auxiliary member 4; each detection element 3 starts to run the plate quickly; after the running plate is completed, observe the detection result through the observation window on the covering layer 5. During the running plate process, the detection device can be placed vertically, horizontally or in any position, and normal running plate can be achieved.

[0063] In some other embodiments, the sample to be measured is loaded into the protective sleeve 2, and then the bottom of the insertion plate 1 is inserted into the protective sleeve 2 to achieve the contact between the running plate auxiliary member 4 and the sample to be measured, hold for a period of time, and then take it out; the detection element 3 runs the plate, and after one minute, read the detection result corresponding to the analyte on the detection element 3.

[0064] The process of inserting the bottom of the insertion plate 1 into the sample to be measured and holding it can be in a static state or a moving state; the holding method is preferably the static state. The holding duration is 1 second to 1 hour, preferably 1 to 15 seconds.

[0065] Embodiment 2

[0066] A rapid detection device for detecting liquid samples. The difference between this embodiment and Embodiment 1 is only that: only one side of the insertion plate 1 is the detection surface, and no card slot 1-1 is provided on the other detection surface.

Claims

1. A liquid sample rapid detection device, comprising an insert plate (1), a detection element (3), a running plate auxiliary member (4) and a covering layer (5); characterized in that: One or more detection surfaces are provided on the plug board (1); the detection surface of the plug board (1) is provided with a detection area and a sample cavity (1-4); the detection area is provided with a card slot (1-1) or a plurality of card slots (1-1) arranged side by side; the ends of each card slot (1-1) are connected to the sample cavity (1-4); the detection element (3) is installed in the card slot (1-1); the sample loading area of ​​the detection element (3) is in the sample cavity (1-4); a running board auxiliary part (4) for absorbing liquid is provided in the sample cavity (1-4); the running board auxiliary part (4) covers the sample loading areas of all the detection elements (3) on the same detection surface; the covering layer (5) is attached to the detection surface of the plug board (1); and a sample loading window (5-1) aligned with the running board auxiliary part (4) is provided on the covering layer (5).

2. A liquid sample rapid detection device according to claim 1, characterized in that: The running board auxiliary component (4) is made of glass fiber sheet, polyester film or absorbent paper.

3. A liquid sample rapid detection device according to claim 1, characterized in that: Only one side surface of the plug board (1) is a detection surface.

4. A liquid sample rapid detection device according to claim 1, characterized in that: Both side surfaces of the plug board (1) are detection surfaces.

5. A liquid sample rapid detection device according to claim 4, characterized in that: The card slots on the two detection surfaces of the plug board (1) are aligned respectively; n sample flow holes (1-5) are provided at the bottom of the plug board (1); n is the number of card slots on a single detection surface; the n sample flow holes (1-5) are aligned with the ends of the n card slots (1-1) on the same detection surface; the sample cavities (1-4) on the two detection surfaces of the plug board (1) are connected via the sample flow holes (1-5).

6. A liquid sample rapid detection device according to claim 1, characterized in that: Any two adjacent card slots (1-1) on the same detection surface are separated by a convex rib (1-3); the convex rib (1-3) is provided with an opening (1-8) for connecting the two adjacent card slots (1-1).

7. A liquid sample rapid detection device according to claim 6, characterized in that: A channel structure (1-7) is provided in part or all of the convex ribs (1-3); the length direction of the channel structure (1-7) is parallel to the length direction of the card slot, and the bottom end is connected to the sample cavity.

8. The liquid sample rapid detection device according to claim 1, characterized in that: The entire or part of the detection surface of the plug board (1) is provided with a residual sample storage cavity (1-6) located above the detection area; the top of the channel structure (1-7) is connected to the residual sample storage cavity (1-6).

9. The liquid sample rapid detection device according to claim 1, characterized in that: It also comprises a protective cover (2); the protective cover (2) is provided with a slot structure corresponding to the bottom of the plug board (1); in an initial state, the bottom of the plug board (1) is plugged into the slot structure on the protective cover (2).

10. A liquid sample rapid detection device according to claim 9, characterized in that: One or more reinforcement structures (2-1) are arranged on the inner side wall of the protective cover (2).

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