Anti-blocking vinorelbine liposome injection mixer

Abstract

The utility model discloses an anti-clogging vinorelbine liposome injection mixer, which relates to the technical field of medical drug preparation, and comprises a mixing outer cylinder, the middle part of the front end of the mixing outer cylinder is movably connected with a maintenance window, the middle part of the bottom end of the mixing outer cylinder is integrally connected with a blanking cylinder, and the upper end of the interior of the blanking cylinder is rotatably connected with a sealing cover. A connecting rod is connected to the middle of the sealing cover in a penetrating mode, an adjusting button is connected to the outer side of the right end of the connecting rod, a filter screen is slidably connected to the bottom end in the discharging barrel, supporting rods are fixedly connected to the left end and the right end of the filter screen, and connecting rods are fixedly connected to the upper ends of the supporting rods. The anti-blocking vinorelbine lipidosome injection mixer is provided with the connecting rod, the connecting rod is driven by the driving piece to drive the filter screen to move up and down, so that the liquid medicine discharging efficiency is improved, medicine residues and the like are prevented from being deposited and blocking the filter screen, the detachable material cover is correspondingly matched to be opened, and the filter screen is taken out for fine cleaning; the medicine residue is prevented from influencing subsequent medicine mixing and blocking filter screen holes.

Description

Technical Field

[0001] The utility model relates to the technical field of medical drug preparation, in particular to a clogging-proof Vinorelbine Tartrate Liposome Injection Mixer. Background Technique

[0002] Vinorelbine tartrate is a white or off-white powder or crystalline powder. It is a semi-synthetic vinblastine antitumor new drug with high anti-cancer activity and a broad anti-tumor spectrum. Liposome is a targeted drug carrier. It can activate the body's own immune function by being phagocytosed by the macrophage system, and change the in-vivo distribution of the encapsulated drug, so that the drug mainly accumulates in tissues and organs such as the liver, spleen, lungs and bone marrow, thereby increasing the therapeutic index of the drug, reducing the therapeutic dose of the drug and reducing the toxicity of the drug.

[0003] For example, the utility model with the application number CN202320187634.7 discloses a Vinorelbine Tartrate Liposome Injection Mixer with a clogging-proof function, belonging to the technical field of medical drug preparation. It includes a mixer body. A gas storage cavity and a gas delivery component are arranged at the top of the mixer body. The inner side of the gas delivery component is communicated with the mixer body. An outlet and a metering mechanism are arranged at the bottom of the mixer body. The utility model solves the problem of easy clogging of the existing drug outlet. The liposome suspension and the lyophilized support are put into the mixer body. A hose is connected to an external blower. The gas is sprayed into the mixer body through the pipe body. The sprayed air flow causes the flow direction of the drug to change, thereby accelerating the mixing speed. After the mixing is completed, the outlet is opened, and the motor is started to drive the stirring plate to rotate by the rotating shaft, so as to play a role in quantitatively controlling the discharged liquid medicine and prevent the liquid medicine from gushing out and causing the outlet to be blocked.

[0004] The mixers similar to the above application still have the following deficiencies:

[0005] Some of the unmixed liquid medicine inside the mixer is likely to accumulate and block at the outlet, and at the same time, it is difficult to clean the outlet after preparation.

[0006] Therefore, in view of this, research and improvement are carried out on the existing structure and deficiencies, and a clogging-proof Vinorelbine Tartrate Liposome Injection Mixer is proposed. Content of the Utility Model

[0007] The purpose of the utility model is to provide a clogging-proof Vinorelbine Tartrate Liposome Injection Mixer to solve the problems raised in the above background technique.

[0008] To achieve the above object, the present utility model provides the following technical solutions: An anti-clogging vinorelbine liposome injection mixer, comprising a mixing outer cylinder, the middle of the front end of the mixing outer cylinder is movably connected with a maintenance window, the middle of the bottom end of the mixing outer cylinder is integrally connected with a feeding cylinder, the upper end inside the feeding cylinder is rotatably connected with a sealing cover, a connecting rod runs through the middle of the sealing cover, an adjusting knob is connected to the outside of the right end of the connecting rod, a filter screen is slidably connected to the bottom end inside the feeding cylinder, support rods are fixedly connected to the left and right ends of the filter screen, a connecting rod is fixedly connected to the upper end of the support rods, a spring is sleeved in the middle of the connecting rod, a driving motor is arranged at the lower left side of the mixing outer cylinder, an eccentric wheel is connected to the output end of the driving motor, a material cover is threadedly connected to the bottom end of the feeding cylinder, fixing seats are fixedly connected to the middle of the left and right sides of the feeding cylinder, and a diversion cylinder is fixedly connected to the middle inside the feeding cylinder.

[0009] Further, an upper cover is connected to the upper end of the mixing outer cylinder, feeding boxes are slidably connected to the left and right sides of the upper cover, and inclined plates are fixedly connected to the inside of the feeding boxes.

[0010] Further, the feeding boxes are communicated with the mixing outer cylinder through the upper cover.

[0011] Further, a placing seat is fixedly connected to the bottom end of the mixing outer cylinder, and the placing seat is in an open ring shape.

[0012] Further, a sliding groove is formed inside the placing seat, and a seat door is slidably connected to the inside of the sliding groove.

[0013] Further, the filter screen is in transmission connection with the driving motor through the support rods, the connecting rod and the eccentric wheel, and the connecting rod is elastically connected to the spring through the fixing seat.

[0014] Further, the diversion cylinder is in a hollow frustum shape, and the filter screen is in an inward concave frustum shape.

[0015] The present utility model provides an anti-clogging vinorelbine liposome injection mixer, which has the following beneficial effects:

[0016] The present utility model is provided with a connecting rod. By driving the connecting rod to drive the filter screen to move up and down, the liquid medicine discharge efficiency is improved, and the deposition of medicinal residues and the like is avoided from clogging the filter. Correspondingly, the detachable material cover is opened, and the filter screen is taken out for fine cleaning, so as to avoid the influence of residual medicinal residues on subsequent drug mixing and the clogging of the filter screen pores. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic front view of the overall structure of an anti-clogging vinorelbine liposome injection mixer of the present utility model;

[0018] Figure 2Schematic internal sectional view of the material discharge cylinder of a clog - proof vinorelbine liposome injection mixer of the present utility model;

[0019] Figure 3 Schematic connection structure diagram of the material discharge cylinder and the drainage cylinder of a clog - proof vinorelbine liposome injection mixer of the present utility model.

[0020] In the figure: 1. Mixing outer cylinder; 2. Upper cover; 3. Feeding box; 4. Inclined plate; 5. Maintenance window; 6. Material discharge cylinder; 7. Sealing cover; 8. Connecting rod; 9. Adjusting knob; 10. Filter screen; 11. Support rod; 12. Connecting rod; 13. Spring; 14. Driving motor; 15. Eccentric wheel; 16. Material cover; 17. Fixed seat; 18. Drainage cylinder; 19. Placing seat; 20. Chute; 21. Seat door. Specific embodiments

[0021] The following further describes in detail the embodiments of the present utility model in conjunction with the drawings and embodiments. The following embodiments are used to illustrate the present utility model, but cannot be used to limit the scope of the present utility model.

[0022] As Figure 1 and Figure 2 shown, a clog - proof vinorelbine liposome injection mixer includes a mixing outer cylinder 1. A maintenance window 5 is movably connected to the middle of the front end of the mixing outer cylinder 1. The middle of the bottom end of the mixing outer cylinder 1 is integrally connected with a material discharge cylinder 6. The upper end inside the material discharge cylinder 6 is rotatably connected with a sealing cover 7. A connecting rod 8 penetrates through the middle of the sealing cover 7. The outer side of the right end of the connecting rod 8 is connected with an adjusting knob 9. The bottom end inside the material discharge cylinder 6 is slidably connected with a filter screen 10. The left and right ends of the filter screen 10 are fixedly connected with support rods 11. The upper ends of the support rods 11 are fixedly connected with a connecting rod 12. A spring 13 is sleeved in the middle of the connecting rod 12. A driving motor 14 is arranged at the left end below the mixing outer cylinder 1. The output end of the driving motor 14 is connected with an eccentric wheel 15. The bottom end of the material discharge cylinder 6 is threadedly connected with a material cover 16. The middle parts of the left and right sides of the material discharge cylinder 6 are fixedly connected with fixed seats 17. The filter screen 10 is in transmission connection with the driving motor 14 through the support rods 11, the connecting rod 12 and the eccentric wheel 15. The connecting rod 12 is elastically connected with the spring 13 through the fixed seat 17. Driven by the driving motor 14, the eccentric wheel 15 rotates rapidly, driving the connecting rod 12 to reciprocate up and down, thereby driving the filter screen 10 integrated with the support rods 11 to slide up and down, vibrating the mixed liquid medicine stored in the middle of the upper end of the filter screen 10. On the one hand, it improves the efficiency of liquid medicine discharge, and on the other hand, it can vibrate the incompletely mixed liquid medicine, facilitating the discharge of the mixed liquid and preventing blockage.

[0023] As Figure 2 and Figure 3As shown, a drainage cylinder 18 is fixedly connected to the middle end inside the blanking cylinder 6. The drainage cylinder 18 is in a hollow frustum shape, and the filter screen 10 is in an inwardly concave frustum shape. The drainage cylinder 18 is a hollow frustum-shaped structure with a wider upper part and a narrower lower part, which can guide the liquid medicine inside the mixing outer cylinder 1 to flow into the concave part in the middle of the filter screen 10 for liquid drainage.

[0024] As Figure 1 shown, an upper cover 2 is connected to the upper end of the mixing outer cylinder 1. Feeding boxes 3 are slidably connected to the left and right sides of the upper cover 2. An inclined plate 4 is fixedly connected inside the feeding boxes 3. The feeding boxes 3 are communicated with the mixing outer cylinder 1 through the upper cover 2. The feeding boxes 3 provided at the left and right ends of the upper cover 2 can slide outward or contract inward, so as to facilitate the expansion of feeding during feeding and retract into the upper cover 2 for sealing when not in use, reducing pollution and improving the protection effect. A placing seat 19 is fixedly connected to the bottom end of the mixing outer cylinder 1. The placing seat 19 is in an open ring shape. A sliding groove 20 is formed inside the placing seat 19. A seat door 21 is slidably connected inside the sliding groove 20. An opening is provided at the front end of the annular placing seat 19 at the bottom end of the mixing outer cylinder 1, which is used for placing the material receiving part to pass through. At the same time, the seat door 21 matching the shape of the placing seat 19 slides and adjusts along with the sliding groove 20, so as to be closed when not in use, preventing external dust and other sundries from invading and affecting the blanking cylinder 6.

[0025] In summary, as Figures 1 to 3As shown, when the anti-clogging vinorelbine liposome injection mixer is in use, first, pull out the feeding boxes 3 at the left and right ends of the upper cover 2 outwards, and then inject materials through the left and right feeding boxes 3 respectively. Inclined plates 4 are arranged inside both feeding boxes 3, so that the injected mixture can be guided downward by the inclined plates 4 and discharged through the upper cover 2 and into the internal part of the mixing outer cylinder 1. Then, push the feeding boxes 3 back into the upper cover 2 for sealing, which can prevent the contamination of the liquid medicine and avoid the splashing of the liquid medicine during the mixing process and other impacts. After that, under the drive of the electrical components at the upper end of the upper cover 2, the raw materials inside the mixing outer cylinder 1 are fully mixed until they are fully mixed. Then, pull the seat door 21 to slide left and right to open it, put the cylinder for collecting the liquid medicine into the fixed seat 17, place it directly below the blanking cylinder 6, and then turn the adjustment knob 9 to drive the connecting rod 8 to drive the sealing cover 7 to flip and open the fixed seat 17, so that the mixed liquid medicine inside the mixing outer cylinder 1 is discharged through the drainage cylinder 18, filtered by the filter screen 10, and discharged from the blanking cylinder 6 for collection. At the same time, under the drive of the transmission motor 14, the eccentric wheel 15 rotates rapidly, driving the connecting rod 12 to reciprocate up and down, thereby driving the filter screen 10 integrated with the support rod 11 to slide up and down, vibrating the mixed liquid medicine stored in the middle of the upper end of the filter screen 10, vibrating the liquid medicine that is not fully mixed, facilitating the discharge of the mixed liquid, preventing clogging, and improving the discharge efficiency of the liquid medicine. Correspondingly, the spring 13 in the middle of the connecting rod 12 is elastically buffered with the placement seat 19 at the outer end of the blanking cylinder 6, reducing the impact on the filter screen 10, the support rod 11, the blanking cylinder 6, and the material cover 16, and improving the screening and filtering effect of the liquid medicine. Finally, after the liquid medicine is discharged, clean the inside, and can cooperate with the opening of the inspection window 5 to clean the inside carefully. Correspondingly, rotate the spiral material cover 16 to open it, take out the internal filter screen 10 for cleaning, etc., to prevent the attachment of medicinal residues, etc., which not only affects the next mixing of the liquid medicine, but also is easy to accumulate and block the discharge of the liquid medicine. In this way, the use process of the entire anti-clogging vinorelbine liposome injection mixer is completed.

[0026] The embodiments of the present invention are given for purposes of illustration and description, and are not exhaustive or limit the present invention to the disclosed form. Many modifications and variations are obvious to those of ordinary skill in the art. The embodiments are selected and described to better illustrate the principles and practical applications of the present invention, and enable those of ordinary skill in the art to understand the present invention and thus design various embodiments with various modifications suitable for specific purposes.

Claims

1. A clogging-proof Vinorelbine liposome injection mixer, comprising a mixing outer cylinder (1), characterized in that: A maintenance window (5) is movably connected to the middle of the front end of the mixing outer cylinder (1). A blanking cylinder (6) is integrally connected to the middle of the bottom end of the mixing outer cylinder (1). A sealing cover (7) is rotatably connected to the upper end inside the blanking cylinder (6). A connecting rod (8) is connected through the middle of the sealing cover (7). An adjusting knob (9) is connected to the outer side of the right end of the connecting rod (8). A filter screen (10) is slidably connected to the bottom end inside the blanking cylinder (6). Support rods (11) are fixedly connected to the left and right ends of the filter screen (10). A connecting rod (12) is fixedly connected to the upper end of the support rod (11). A spring (13) is sleeved on the middle of the connecting rod (12). A driving motor (14) is arranged on the left end of the lower side of the mixing outer cylinder (1). An eccentric wheel (15) is connected to the output end of the driving motor (14). A material cover (16) is threadedly connected to the bottom end of the blanking cylinder (6). Fixed seats (17) are fixedly connected to the middle of the left and right sides of the blanking cylinder (6). A diversion cylinder (18) is fixedly connected to the middle end inside the blanking cylinder (6).

2. The anti-clogging vinorelbine liposome injection mixer according to claim 1, wherein An upper cover (2) is connected to the upper end of the mixing outer cylinder (1). Feeding boxes (3) are slidably connected to the left and right sides of the upper cover (2). An inclined plate (4) is fixedly connected to the inside of the feeding box (3).

3. The anti-blocking vinorelbine liposome injection mixer according to claim 2, characterized in that The feeding box (3) is communicated with the mixing outer cylinder (1) through the upper cover (2).

4. A clogging-proof vinorelbine liposome injection mixer according to claim 1, characterized in that, A placing seat (19) is fixedly connected to the bottom end of the mixing outer cylinder (1). The placing seat (19) is in an open ring shape.

5. The anti-clogging vinorelbine liposome injection mixer according to claim 4, characterized in that, A chute (20) is formed inside the placing seat (19). A seat door (21) is slidably connected to the inside of the chute (20).

6. The anti-clogging vinorelbine liposome injection mixer according to claim 1, characterized in that, The filter screen (10) is in transmission connection with the driving motor (14) through the support rod (11), the connecting rod (12), and the eccentric wheel (15). The connecting rod (12) is elastically connected to the spring (13) through the fixed seat (17).

7. The anti-clogging vinorelbine liposome injection mixer according to claim 1, wherein The diversion cylinder (18) is in a hollow frustum shape. The filter screen (10) is in an inward concave frustum shape.

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