Liquid nitrogen container device for storing tissue embryos

By designing an automated liquid nitrogen tank device and using a servo motor and electric cylinder to drive the sealing cover, the problem of inconvenient storage of embryos in the liquid nitrogen tank is solved, and the effect of automated storage and reasonable utilization of the liquid nitrogen tank space is achieved.

CN223080918UActive Publication Date: 2025-07-11HUANGS SAIER BIOTECHNOLOGY (GUANGXI) CO LTD
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Patent Information

Application Number
CN202422143653.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-02
Publication Date
2025-07-11
Estimated Expiration
2034-09-02

AI Technical Summary

Technical Problem

In the prior art, tissue embryos are inconvenient to store and take up in liquid nitrogen tanks, and the liquid nitrogen storage space is unreasonable and requires frequent manual operations.

Method used

A liquid nitrogen tank device including a support structure and an embryo storage structure is designed. The movement of the sealing cover is driven by a servo motor and a electric cylinder, and the suspension and positioning of the embryo storage part is realized through a special-shaped moving block and a locking nut, and the opening operation of the liquid nitrogen tank is automatically controlled.

Benefits of technology

It realizes automation and simplification of embryo storage, rationally utilizes the liquid nitrogen tank space, reduces manual operations, and improves storage and access efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a liquid nitrogen container device for storing tissue embryos, and belongs to the technical field of tissue embryo storage. The tissue and embryo storage liquid nitrogen container device comprises a supporting structure and an embryo storage structure. The supporting structure comprises a supporting seat, a sliding rail and a driving part, a supporting rod and an electric cylinder are installed between the supporting seat and the sliding rail, and the driving part is installed on the sliding rail; the embryo storage structure comprises a liquid nitrogen tank, a buffer piece, a hollow pipe and a movable connecting piece, the liquid nitrogen tank is placed on the top surface of the supporting seat, a sealing cover is installed at an opening in the upper end of the liquid nitrogen tank through a hasp, and the movable connecting piece is slidably connected to the interior of the sliding groove and the interior of the hollow pipe; an embryo storage part is inserted into the movable connecting piece. When embryos are stored, the space of the liquid nitrogen tank can be reasonably utilized to suspend and store the embryos, meanwhile, manual operation is reduced, and the embryos can be taken more simply and conveniently.
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Description

Technical Field

[0001] The utility model relates to the technical field of tissue embryo storage, and particularly relates to a liquid nitrogen tank device for storing tissue embryos. Background Technique

[0002] Cryopreserving embryos is the only method in the world that can maturely preserve fertility function. This technology involves embryos obtained through in vitro cultivation techniques. Blastocysts are the final stage of embryo culture in vitro. The embryos are stored in a liquid nitrogen environment at -196°C for long-term preservation. Embryo cryopreservation technology is a key link in the embryo industry system. Different embryo storage devices used during embryo cryopreservation result in different cooling rates and preservation effects, and thus different degrees of cryo-injury to the embryos. Therefore, it is crucial to screen more efficient in vitro embryo cryopreservation schemes. Optimizing cryopreservation can effectively improve the survival rate and developmental ability of embryos after cryopreservation.

[0003] Currently, placing tissue embryos in liquid nitrogen is a common method for preserving embryos. However, during the placement and retrieval processes, it requires manual opening and closing. At the same time, it is not possible to reasonably place the tissue embryos into the liquid nitrogen tank according to the liquid level height of the liquid nitrogen. This is not convenient during retrieval and is also not conducive to the rational utilization of the liquid nitrogen storage space. For this reason, it is necessary to propose a liquid nitrogen tank device for storing tissue embryos to solve the above problems. Summary of the Utility Model

[0004] To make up for the above deficiencies, the utility model provides a liquid nitrogen tank device for storing tissue embryos, aiming to improve the problems that it requires manual opening and closing during the placement and retrieval processes, and it is not possible to reasonably place the tissue embryos into the liquid nitrogen tank according to the liquid level height of the liquid nitrogen, which is not convenient during retrieval and is also not conducive to the rational utilization of the liquid nitrogen storage space.

[0005] The utility model is implemented as follows:

[0006] The utility model provides a liquid nitrogen tank device for storing tissue embryos, including a support structure and an embryo storage structure.

[0007] The support structure includes a support base, a slide rail, and a driving member. A support rod and an electric cylinder are installed between the support base and the slide rail, and the driving member is installed on the slide rail. The embryo storage structure includes a liquid nitrogen tank, a buffer member, a hollow tube, and a movable connecting member. The liquid nitrogen tank is placed on the top surface of the support base. A sealing cover is installed at the upper opening of the liquid nitrogen tank through a buckle. A buffer member is installed on the sealing cover, and the buffer member is connected to the driving member. The hollow tube is fixed on the sealing cover. A chute is provided inside the hollow tube, and the movable connecting member is slidably connected inside the chute and the hollow tube. An embryo storage part is inserted into the movable connecting member.

[0008] In one embodiment of the utility model, a placement groove matching the liquid nitrogen tank is provided on the top surface of the support base, and universal wheels are circumferentially installed on the bottom of the support base.

[0009] In one embodiment of the utility model, the driving member includes two threaded rods, a servo motor and a slider. The two threaded rods are rotatably connected to the inside of the slide rail, and the two threaded rods are connected to each other through a transmission part. The servo motor is installed on one side of the slide rail and connected to one of the threaded rods. The slider is threaded through the threaded rod, and the slider is slidably connected to the inside of the slide rail. A connecting frame is fixed to the top surface of the slider.

[0010] In an embodiment of the utility model, the transmission part includes two transmission wheels and a transmission chain, the two transmission wheels are respectively key-connected to the two threaded rods, and the transmission chain is transmission-connected to the two transmission wheels.

[0011] In one embodiment of the utility model, the buffer member includes a movable plate and a connecting column, the connecting column slides through the movable plate, one end of the connecting column is fixed to the sealing cover, and the other end of the connecting column is fixed to a limiting plate. A spring is sleeved on the connecting column, and the two ends of the spring are respectively fixed to the limiting plate and the movable plate, and the movable plate is fixed to the connecting frame.

[0012] In an embodiment of the present utility model, through holes matching the connecting posts are provided inside the movable plate, and the connecting posts are circumferentially distributed on the movable plate.

[0013] In one embodiment of the utility model, the movable connecting piece includes a special-shaped movable block and an insert tube, the special-shaped movable block is slidably connected to the inside of the hollow tube and the slide groove, a threaded column is fixed on one side of the special-shaped movable block, the threaded column passes through the slide groove and extends to the outside, a locking nut is threadedly connected to the threaded column, and the insert tube is symmetrically fixed on the other side of the special-shaped movable block.

[0014] In one embodiment of the utility model, the embryo storage part is an embryo storage bucket and an embryo storage box, and a plug-in column is fixed on one side of the embryo storage bucket and the embryo storage box, and the plug-in column is plugged into the interior of the insertion tube.

[0015] The beneficial effects of the present utility model are as follows: An apparatus for storing tissue embryos in a liquid nitrogen tank obtained by the above design. When in use, hang the embryo storage part containing embryos on the insertion tube, then move the special-shaped movable block up and down to a suitable position, and position and fix the special-shaped movable block by rotating the locking nut. Since the special-shaped movable block can slide in the hollow tube, it can be used to hang embryo storage parts of different heights. Then, use the electric cylinder to drive the slide rail to move upward. When it reaches a suitable height, use the driving member to move the sealing cover above the filling port of the tank. At this time, use the electric cylinder to retract to insert the embryo storage part into the liquid nitrogen tank, and at the same time, use the buckle to fix the sealing cover at the filling port of the liquid nitrogen tank to complete the storage operation. Conversely, the embryo storage part can be taken out. In this way, when storing embryos, the space of the liquid nitrogen tank can be reasonably utilized to store the embryos suspended, and at the same time, reducing manual operation for taking and placing embryos can be simpler and more convenient. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the following will briefly introduce the drawings required for the embodiments. It should be understood that the following drawings only show some embodiments of the present utility model, and thus should not be regarded as limiting the scope. For those of ordinary skill in the art, without creative efforts, other related drawings can also be obtained based on these drawings.

[0017] Figure 1 is a schematic structural diagram of the apparatus for storing tissue embryos in a liquid nitrogen tank provided by the embodiment of the present utility model;

[0018] Figure 2 is a schematic structural diagram of the support of the apparatus for storing tissue embryos in a liquid nitrogen tank provided by the embodiment of the present utility model;

[0019] Figure 3 is a schematic structural diagram of the driving member of the apparatus for storing tissue embryos in a liquid nitrogen tank provided by the embodiment of the present utility model;

[0020] Figure 4 is a schematic cross-sectional structural diagram of the liquid nitrogen tank of the apparatus for storing tissue embryos in a liquid nitrogen tank provided by the embodiment of the present utility model;

[0021] Figure 5 is a schematic diagram of a partially disassembled structure of the apparatus for storing tissue embryos in a liquid nitrogen tank provided by the embodiment of the present utility model;

[0022] Figure 6 is of the present utility model Figure 5 Enlarged view at A in

[0023] In the figure: 100 - support structure; 110 - support base; 111 - universal wheel; 120 - slide rail; 130 - support rod; 140 - electric cylinder; 150 - driving member; 151 - threaded rod; 152 - servo motor; 153 - slider; 154 - connecting frame; 155 - transmission part; 1551 - transmission wheel; 1552 - transmission chain; 200 - embryo storage structure; 210 - liquid nitrogen tank; 220 - sealing cover; 230 - buffer member; 231 - movable plate; 232 - connecting column; 233 - limiting plate; 234 - spring; 240 - hollow tube; 241 - chute; 250 - movable connecting piece; 251 - special-shaped movable block; 252 - threaded column; 253 - locking nut; 254 - insertion tube; 260 - embryo storage part. Detailed implementation manners

[0024] To make the objectives, technical solutions, and advantages of the embodiments of the present utility model clearer, the technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model. Apparently, the described embodiments are only a part rather than all of the embodiments of the present utility model. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0025] Embodiment

[0026] Please refer to Figures 1 - 6 , the present utility model provides a technical solution: a liquid nitrogen tank device for storing tissue embryos, including a support structure 100 and an embryo storage structure 200.

[0027] Please refer to Figure 1 and Figure 2 , the support structure 100 includes a support base 110, a slide rail 120, and a driving member 150. A support rod 130 and an electric cylinder 140 are installed between the support base 110 and the slide rail 120, and the driving member 150 is installed on the slide rail 120.

[0028] The top surface of the support seat 110 is provided with a placement groove that matches the liquid nitrogen tank 210. The bottom of the support seat 110 is circumferentially installed with universal wheels 111. The universal wheels 111 can move the device to improve the flexibility of transfer. The driving member 150 includes two threaded rods 151, a servo motor 152 and a slider 153. The two threaded rods 151 are rotatably connected to the inside of the slide rail 120. The two threaded rods 151 are connected to each other through a transmission part 155. The servo motor 152 is installed on one side of the slide rail 120 and connected to a threaded rod 151. Here, the end of the output shaft of the servo motor 152 is connected to a threaded rod 151. The slider 153 is threaded through the threaded rod 151. The slider 153 is slidably connected to the slide rail 120. Internally, a connecting frame 154 is fixed to the top surface of the slider 153; the transmission part 155 includes two transmission wheels 1551 and a transmission chain 1552, the two transmission wheels 1551 are respectively keyed to the two threaded rods 151, and the transmission chain 1552 is transmission-connected to the two transmission wheels 1551. Here, the servo motor 152 working under the action of the transmission part 155 can simultaneously drive the two threaded rods 151 to rotate, and the rotation of the threaded rods 151 can make the slider 153 and the connecting frame 154 move.

[0029] See also Figures 1 - 6 The embryo storage structure 200 includes a liquid nitrogen tank 210, a buffer 230, a hollow tube 240 and a movable connecting member 250. The liquid nitrogen tank 210 is placed on the top surface of the support seat 110. A sealing cover 220 is installed at the upper opening of the liquid nitrogen tank 210 through a buckle. The sealing cover 220 is installed with a buffer 230. The buffer 230 is connected to the driving member 150. The hollow tube 240 is fixed on the sealing cover 220. Here, a sealing ring is provided between the sealing cover 220 and the tank mouth of the liquid nitrogen tank 210, so that the sealing performance can be enhanced. A chute 241 is provided inside the hollow tube 240. The movable connecting member 250 is slidably connected to the chute 241 and the inside of the hollow tube 240. The embryo storage part 260 is plugged into the movable connecting member 250.

[0030] The buffer member 230 includes a movable plate 231 and a connecting column 232. The connecting column 232 slides through the movable plate 231. One end of the connecting column 232 is fixed to the sealing cover 220, and the other end of the connecting column 232 is fixed to the limiting plate 233. A spring 234 is sleeved on the connecting column 232. The two ends of the spring 234 are respectively fixed to the limiting plate 233 and the movable plate 231. The movable plate 231 is fixed to the connecting frame 154. A through hole matching the connecting column 232 is opened inside the movable plate 231. The connecting column 232 is circumferentially distributed on the movable plate 231. The setting of the buffer member 230 here can facilitate the sealing cover 220 to be further fixed to the liquid nitrogen tank 210 through a buckle.

[0031] The movable connecting piece 250 includes a special-shaped movable block 251 and an insertion tube 254. The special-shaped movable block 251 is slidably connected inside the hollow tube 240 and the chute 241. A threaded post 252 is fixed on one side of the special-shaped movable block 251. The threaded post 252 penetrates through the chute 241 and extends to the outside. A locking nut 253 is threadedly connected to the threaded post 252. The insertion tubes 254 are symmetrically fixed on the other side of the special-shaped movable block 251. The embryo storage part 260 is an embryo storage barrel and an embryo storage box. Insertion posts are fixed on one side of both the embryo storage barrel and the embryo storage box. The insertion posts are inserted inside the insertion tubes 254. Here, several movable connecting pieces 250 are provided. By using the movable connecting pieces 250, it is convenient to hang the storage barrel and storage box for storing embryos, so that they can be in a suspended state and the storage space of the liquid nitrogen tank 210 can be reasonably utilized. At the same time, the distance between the movable connecting pieces 250 can be adjusted, so that it can adapt to embryo storage devices of different sizes and be more flexible in use.

[0032] Specifically, the working principle of the tissue embryo storage liquid nitrogen tank device: When in use, hang the embryo storage part 260 containing embryos on the insertion tube 254, then move the special-shaped movable block 251 up and down to a suitable position, and position and fix the special-shaped movable block 251 by rotating the locking nut 253. Since the special-shaped movable block 251 can slide in the hollow tube 240, it is suitable for hanging embryo storage parts 260 of different heights. Then, drive the slide rail 120 to move upward by the electric cylinder 140. When it moves to a suitable height, the servo motor 152 drives the two threaded rods 151 to rotate simultaneously under the action of the transmission part 155. In this way, the slider 153 and the connecting frame 154 will drive the sealing cover 220 to move towards the filling port of the liquid nitrogen tank 210. When the sealing cover 220 moves to the upper inlet of the liquid nitrogen tank 210, the electric cylinder 140 retracts to insert the embryo storage part 260 into the liquid nitrogen tank 210. At the same time, use the buckle to fix the sealing cover 220 at the filling port of the liquid nitrogen tank 210 to complete the storage operation. Conversely, the embryo storage part 260 can be taken out. In this way, when storing embryos, the space of the liquid nitrogen tank 210 can be reasonably utilized to store the embryos in a suspended state, and at the same time, reducing manual operation for taking and placing embryos can be more simple and convenient.

[0033] It should be noted that the specific model specifications of the electric cylinder 140 and the servo motor 152 need to be selected and determined according to the actual specifications of the device. The specific selection calculation method adopts the existing technology in this field, so it will not be elaborated in detail here.

[0034] The power supply and principle of the electric cylinder 140 and the servo motor 152 are clear to those skilled in the art and will not be described in detail here.

[0035] The above are only the preferred embodiments of the present utility model and are not intended to limit the present utility model. For those skilled in the art, various modifications and variations can be made to the present utility model. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.

Claims

1. A liquid nitrogen tank device for storing tissue embryos, comprising a support structure (100) and an embryo storage structure (200) mounted on the support structure (100), characterized in that: The support structure (100) comprises a support seat (110), a slide rail (120) and a driving member (150); a support rod (130) and an electric cylinder (140) are installed between the support seat (110) and the slide rail (120); and the driving member (150) is installed on the slide rail (120); The embryo storage structure (200) comprises a liquid nitrogen tank (210), a buffer component (230), a hollow tube (240) and a movable connecting component (250). The liquid nitrogen tank (210) is placed on the top surface of the support seat (110). A sealing cover (220) is installed at the upper opening of the liquid nitrogen tank (210) by means of a buckle. A buffer component (230) is installed on the sealing cover (220). The buffer component (230) is connected to the driving component (150). The hollow tube (240) is fixed on the sealing cover (220). A slide groove (241) is provided inside the hollow tube (240). The movable connecting component (250) is slidably connected to the slide groove (241) and the inside of the hollow tube (240). The embryo storage part (260) is plugged into the movable connecting component (250).

2. The device for storing tissue embryos in a liquid nitrogen tank according to claim 1, characterized in that, A placement groove matching the liquid nitrogen tank (210) is provided on the top surface of the support seat (110), and a universal wheel (111) is circumferentially mounted on the bottom of the support seat (110).

3. The liquid nitrogen tank device for storing tissue embryos according to claim 1, wherein The driving member (150) comprises two threaded rods (151), a servo motor (152) and a slider (153); the two threaded rods (151) are rotatably connected to the inside of the slide rail (120); the two threaded rods (151) are transmission-connected via a transmission part (155); the servo motor (152) is installed on one side of the slide rail (120) and is connected to one of the threaded rods (151); the slider (153) is threadedly penetrated through the threaded rod (151); the slider (153) is slidably connected to the inside of the slide rail (120); and a connecting frame (154) is fixed to the top surface of the slider (153).

4. An apparatus for storing tissue embryos in a liquid nitrogen tank according to claim 3, characterized in that, The transmission part (155) comprises two transmission wheels (1551) and a transmission chain (1552); the two transmission wheels (1551) are respectively key-connected to the two threaded rods (151); and the transmission chain (1552) is transmission-connected to the two transmission wheels (1551).

5. The device for storing tissue embryos in a liquid nitrogen tank according to claim 3, wherein, The buffer member (230) includes a movable plate (231) and a connecting column (232). The connecting column (232) slidably penetrates through the movable plate (231). One end of the connecting column (232) is fixed to the sealing cover (220), and a limiting plate (233) is fixed to the other end of the connecting column (232). A spring (234) is sleeved on the connecting column (232), and both ends of the spring (234) are fixed to the limiting plate (233) and the movable plate (231) respectively. The movable plate (231) is fixed to the connecting frame (154).

6. The liquid nitrogen tank device for storing tissue embryos according to claim 5, characterized in that, A through hole matching the connecting column (232) is formed inside the movable plate (231), and the connecting columns (232) are circumferentially distributed on the movable plate (231).

7. An apparatus for storing liquid nitrogen for tissue embryos according to claim 1, characterized in that, The movable connecting member (250) includes a special-shaped movable block (251) and an insertion tube (254). The special-shaped movable block (251) is slidably connected inside the hollow tube (240) and the chute (241). A threaded column (252) is fixed to one side of the special-shaped movable block (251). The threaded column (252) penetrates through the chute (241) and extends to the outside, and a locking nut (253) is threadedly connected to the threaded column (252). The insertion tubes (254) are symmetrically fixed to the other side of the special-shaped movable block (251).

8. An apparatus for storing liquid nitrogen for tissue embryos according to claim 7, characterized in that, The embryo storage part (260) is an embryo storage barrel and an embryo storage box. Plug columns are fixed to one side of the embryo storage barrel and the embryo storage box respectively, and the plug columns are inserted into the inside of the insertion tubes (254).