Liquid nitrogen cryopreservation box for tissue anatomy sampling

Abstract

The utility model belongs to the technical field of liquid nitrogen cryopreservation boxes, and particularly relates to a liquid nitrogen cryopreservation box for tissue anatomy sampling, which comprises a box body, an operation box fixedly connected to the lower part of the box body, a bottom plate fixedly connected to the lower part of the operation box, a heat preservation block fixedly connected to the inside of the box body, and a support plate slidably connected to the inside of the box body. A plurality of test tubes are slidably connected into the supporting plate, the test tubes are slidably connected into the heat preservation block, the upper portion of the box body abuts against a box cover, the lower portion of the box cover is fixedly connected with a heat preservation layer, the heat preservation layer abuts against the upper portions of the test tubes, and the lower portion of the supporting plate is highly connected with a plurality of threaded tubes. By arranging the driving assembly and the supporting plate, lifting of the supporting plate is achieved, hands do not need to stretch into the box body, the risk of frostbite is avoided, by arranging the fixing block, the sliding block and the fixing assembly, the box cover is easily opened and fixed, and the stability and safety of samples are maintained.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid nitrogen freezing boxes, in particular to a liquid nitrogen freezing box for tissue dissection sampling. Background Technique

[0002] In medical research and clinical diagnosis, tissue dissection sampling is a crucial task. After sampling, tissue samples need to be stored at extremely low temperatures to maintain their biological activity and structural integrity. The liquid nitrogen freezing box for tissue dissection sampling is a specially designed laboratory device, mainly used for low-temperature preservation of tissues during the biological dissection sampling process.

[0003] The prior art has the following defects or problems: The prior art with the publication number of CN205815765U discloses an improved centrifuge tube preservation box for liquid nitrogen quick freezing. The centrifuge tube preservation box includes a box cover, a box body, and a centrifuge tube seat. A plurality of vertically arranged centrifuge tube seats are evenly spaced along the horizontal direction in the box body. The centrifuge tube can be fitted and placed in the centrifuge tube seat. A liquid nitrogen storage tank is made on the box body below the bottom of the centrifuge tube seat, and a vertically arranged liquid nitrogen inflow through hole is made on the box body between adjacent centrifuge tube seats. The liquid nitrogen in the liquid nitrogen storage tank of this centrifuge tube preservation box will quickly freeze the bottom of the centrifuge tube, and the liquid nitrogen in the liquid nitrogen inflow through hole will quickly freeze the side wall of the centrifuge tube, improving the quick freezing effect. At the same time, since the liquid nitrogen storage tank is arranged below the centrifuge tube seat and the liquid nitrogen inflow through hole, the exposed area of the liquid nitrogen storage tank is reduced, greatly slowing down the evaporation rate of the liquid nitrogen, ensuring the quick freezing effect, saving liquid nitrogen, and bringing convenience to use.

[0004] Although the above device improves the quick freezing effect and slows down the evaporation rate of the liquid nitrogen through the design of the liquid nitrogen storage tank and the liquid nitrogen inflow through hole during use, when adding or removing the centrifuge tube, it is necessary to directly contact the liquid nitrogen environment, there is a risk of frostbite, and it is not convenient enough. There is no fixation between the box body and the box cover, which may cause the box cover to separate and damage the test tube. Content of the Utility Model

[0005] Aiming at the deficiencies of the prior art, the utility model provides a liquid nitrogen freezing box for tissue dissection sampling, which solves the problems of the risk of frostbite when adding or removing test tubes and the damage of test tubes caused by the lack of fixation between the box body and the box cover existing nowadays.

[0006] To achieve the above object, the present utility model provides the following technical solutions: A liquid nitrogen freezing box for tissue dissection sampling, comprising a box body, a manipulation box is fixedly connected to the lower part of the box body, a bottom plate is fixedly connected to the lower part of the manipulation box, a heat preservation block is fixedly connected inside the box body, a support plate is slidably connected inside the box body, a plurality of test tubes are slidably connected inside the support plate, the test tubes are slidably connected inside the heat preservation block, a box cover abuts against the upper part of the box body, a heat preservation layer is fixedly connected to the lower part of the box cover, and the heat preservation layer abuts against the upper parts of the test tubes. A plurality of threaded tubes are highly connected to the lower part of the support plate, and a driving assembly is arranged inside the manipulation box.

[0007] As a preferred technical solution of the present utility model, the driving assembly includes a worm, the worm is rotatably connected inside the manipulation box, a threaded rod is threadedly connected inside the threaded tube, the threaded tube is slidably connected inside the heat preservation block, the threaded rod is rotatably connected to the upper part of the bottom plate, a worm gear is fixedly connected to the lower part of the threaded rod, the worm gear meshes with the worm, and a hand wheel is fixedly connected inside the worm.

[0008] As a preferred technical solution of the present utility model, two fixing blocks are fixedly connected to the outside of the box body, a slider is slidably connected inside the fixing block, the slider is fixedly connected to one side of the box cover, and a fixing assembly is arranged inside the fixing block.

[0009] As a preferred technical solution of the present utility model, the fixing assembly includes a clamping block, the clamping block is slidably connected inside the slider, a connecting plate is fixedly connected to one side of the clamping block, a connecting rod is fixedly connected to the outside of the connecting plate, a sliding plate is fixedly connected to the outside of the connecting rod, and a compression spring is fixedly connected between the connecting rod and the fixing block.

[0010] As a preferred technical solution of the present utility model, a limiting rod is fixedly connected inside the fixing block, the connecting rod is slidably connected to the outer periphery of the limiting rod, and the compression spring is sleeved on the outer periphery of the limiting rod.

[0011] As a preferred technical solution of the present utility model, a plurality of positioning columns are fixedly connected to the lower part of the box cover, and the positioning columns are slidably connected inside the box body.

[0012] As a preferred technical solution of the present utility model, a gripping groove is formed in the upper part of the box cover.

[0013] Compared with the prior art, the present utility model provides a liquid nitrogen freezing box for tissue dissection sampling, which has the following beneficial effects:

[0014] 1. In the present utility model, by providing a driving assembly and a support plate, rotating the handwheel drives the worm to rotate, thereby causing the worm gear to rotate the threaded rod and realizing the lifting of the support plate. Users do not need to put their hands into the box body and do not directly contact the low-temperature environment inside the box body, and can take out the test tubes, avoiding the risk of frostbite. Since the support plate can move up and down, the cryogenic storage box can be designed to be more compact, saving space and reducing the consumption of liquid nitrogen at the same time;

[0015] 2. In the present utility model, by providing a fixing block, a slider and a fixing assembly, when the sliding plate slides outwards, the connecting rod will move accordingly, and the connecting plate drives the clamping block to withdraw from the slot of the slider, and the box cover can be opened. The triangular clamping block enables the slider to directly slide into the fixing block without sliding the sliding plate again, realizing the easy opening and fixing of the box cover, facilitating the access operation of the samples, and ensuring that the samples are not affected by the external environment during storage, maintaining the stability and safety of the samples. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 is a schematic structural diagram of the box body of a liquid nitrogen cryogenic storage box for tissue dissection sampling according to the present utility model;

[0017] Figure 2 is a schematic structural diagram of the worm of a liquid nitrogen cryogenic storage box for tissue dissection sampling according to the present utility model;

[0018] Figure 3 is a schematic structural diagram of the operation box of a liquid nitrogen cryogenic storage box for tissue dissection sampling according to the present utility model;

[0019] Figure 4 is a schematic structural diagram of the compression spring of a liquid nitrogen cryogenic storage box for tissue dissection sampling according to the present utility model.

[0020] In the figure: 1. Box body; 2. Operation box; 3. Bottom plate; 4. Box cover; 5. Heat insulation layer; 6. Heat insulation block; 7. Support plate; 8. Threaded tube; 9. Threaded rod; 10. Worm gear; 11. Worm; 12. Handwheel; 13. Test tube; 14. Holding groove; 15. Fixing block; 16. Slider; 17. Sliding plate; 18. Positioning column; 19. Connecting rod; 20. Connecting plate; 21. Clamping block; 22. Limiting rod; 23. Compression spring. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0021] The technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0022] Please refer to Figures 1-4 In this embodiment, a liquid nitrogen cryopreservation box for tissue dissection sampling includes a box body 1. A manipulation box 2 is fixedly connected to the lower part of the box body 1. A bottom plate 3 is fixedly connected to the lower part of the manipulation box 2. A heat preservation block 6 is fixedly connected inside the box body 1. A support plate 7 is slidably connected inside the box body 1. A plurality of test tubes 13 are slidably connected inside the support plate 7. The test tubes 13 are slidably connected inside the heat preservation block 6. A box cover 4 abuts against the upper part of the box body 1. A heat preservation layer 5 is fixedly connected to the lower part of the box cover 4. The heat preservation layer 5 abuts against the upper parts of the test tubes 13. A plurality of threaded tubes 8 are height-connected to the lower part of the support plate 7. A driving assembly is arranged inside the manipulation box 2. Two fixing blocks 15 are fixedly connected to the outside of the box body 1. A slider 16 is slidably connected inside the fixing block 15. The slider 16 is fixedly connected to one side of the box cover 4. A fixing assembly is arranged inside the fixing block 15. A plurality of positioning columns 18 are fixedly connected to the lower part of the box cover 4. The positioning columns 18 are slidably connected inside the box body 1. A grip groove 14 is formed in the upper part of the box cover 4.

[0023] Specifically, the box body 1 serves as the main structure of the cryopreservation box, providing a container for protecting the internal components and the test tubes 13, and at the same time serving as the installation basis for other components. The manipulation box 2 is located at the lower part of the box body 1 and is used to accommodate the driving assembly and other operating machinery, providing space for operations. The bottom plate 3 is fixed to the lower part of the manipulation box 2, providing stable support for the entire cryopreservation box. The heat preservation block 6 is fixed inside the box body 1, and its main function is to maintain the temperature inside the box, reduce the volatilization of liquid nitrogen, and provide a low-temperature environment for the test tubes 13. The support plate 7 is slidably connected inside the box body 1 and is used to carry the test tubes 13 so that they can move up and down as needed. The test tubes 13 are slidably connected inside the support plate 7 and the heat preservation block 6 and are used to place the tissue samples to be preserved, facilitating individual picking and placing. The box cover 4 covers the upper part of the box body 1 to protect the internal samples from the external environment. The heat preservation layer 5 is fixed to the lower part of the box cover 4, providing additional heat preservation effect and reducing heat exchange. The threaded tubes 8 connect the support plate 7 and the driving assembly, and the support plate 7 can move up and down through threaded connection. The fixing blocks 15 are fixed to the outside of the box body 1 and are used to fix the box cover 4 to ensure sealing. The slider 16 is slidably connected inside the fixing block 15 and is fixedly connected to one side of the box cover 4, and is used for locking and unlocking the box cover 4. The positioning columns 18 ensure the correct alignment between the box cover 4 and the box body 1, further enhancing the fixing effect of the box cover 4. The grip groove 14 on the upper part of the box cover 4 provides a position convenient for the user to apply force, enabling the user to more easily open the box cover 4.

[0024] In this embodiment, the driving assembly includes a worm 11. The worm 11 is rotatably connected inside the manipulation box 2. A threaded rod 9 is threadedly connected inside the threaded tube 8. The threaded tube 8 is slidably connected inside the heat preservation block 6. The threaded rod 9 is rotatably connected to the upper part of the bottom plate 3. A worm gear 10 is fixedly connected to the lower part of the threaded rod 9. The worm gear 10 meshes with the worm 11. A hand wheel 12 is fixedly connected inside the worm 11.

[0025] Specifically, the worm gear 11 is rotatably connected inside the operation box 2. By operating the handwheel 12, the worm gear 11 can rotate, thereby driving the entire drive assembly. The threaded rod 9 is internally threaded with the threaded tube 8. When the worm gear 11 rotates, the worm wheel 10 engaged with it will rotate the threaded rod 9, causing the threaded rod 9 to move up and down inside the threaded tube 8. The support plate 7 is connected to the threaded rod 9. When the threaded rod 9 moves up and down, the support plate 7 also moves up and down accordingly, thereby adjusting the height of the support plate 7. By rotating the handwheel 12, the user can precisely control the height of the support plate 7, enabling the test tube 13 to be pushed to the opening of the box body 1. The user can easily pick up and place the test tube 13 without directly contacting the low-temperature environment inside the box body 1. This design avoids the operator's hand directly entering the low-temperature environment, reduces the risk of frostbite, and also reduces the evaporation of liquid nitrogen caused by the body heat. Since the support plate 7 can move up and down, the cryogenic storage box can be designed to be more compact, saving space and also reducing the consumption of liquid nitrogen because only the area where the test tube 13 is located needs to be kept at a low temperature.

[0026] In this embodiment, the fixing assembly includes a clamping block 21. The clamping block 21 is slidably connected inside the slider 16. One side of the clamping block 21 is fixedly connected to a connecting plate 20. The outside of the connecting plate 20 is fixedly connected to a connecting rod 19. The outside of the connecting rod 19 is fixedly connected to a sliding plate 17. A compression spring 23 is fixedly connected between the connecting rod 19 and the fixing block 15. A limiting rod 22 is fixedly connected inside the fixing block 15. The connecting rod 19 is slidably connected to the outer periphery of the limiting rod 22. The compression spring 23 is sleeved on the outer periphery of the limiting rod 22.

[0027] Specifically, the clamping block 21 is designed as a triangular block and can slide in the slot inside the fixing block 15. When the sliding plate 17 is operated, the clamping block 21 moves accordingly. The triangular corner of it matches the internal structure of the fixing block 15 to achieve the locking of the box cover 4. The connecting plate 20 is used to connect the clamping block 21 and the connecting rod 19. When the sliding plate 17 moves, the connecting plate 20 drives the connecting rod 19 to move, and then the clamping block 21 slides inside the fixing block 15 to complete the locking or unlocking action. One end of the connecting rod 19 is connected to the connecting plate 20, and the other end is connected to the sliding plate 17, converting the operation of the sliding plate 17 into a linear motion of the clamping block 21. The sliding plate 17 is located outside the fixing block 15 for the operator to apply force. By sliding the sliding plate 17, the movement of the connecting rod 19 can be controlled, and then the movement of the clamping block 21 can be driven. The compression spring 23 is sleeved on the outer periphery of the limiting rod 22, providing elastic force to ensure that the fixing assembly can return to the initial position in the unlocked state and providing additional fixing force in the locked state. The limiting rod 22 is fixed inside the fixing block 15, restricting the rotation range of the connecting rod 19 to ensure the accuracy and safety of the operation.

[0028] Working principle and usage process of the present utility model: The user can unlock the lid 4 by pushing the sliding plate 17. When the sliding plate 17 slides outwards, the connecting rod 19 will move accordingly, driving the clamping block 21 to withdraw from the slot of the sliding block 16 through the connecting plate 20. At this time, the lid 4 can be opened. During the process of opening the lid 4, the positioning post 18 will slide along the inside of the box body 1 to ensure the correct alignment between the lid 4 and the box body 1. After the lid 4 is opened, the user can observe the test tube 13 on the support plate 7. Since the support plate 7 can move up and down, the user can drive the worm 11 to rotate by rotating the handwheel 12, and then make the worm gear 10 rotate the threaded rod 9 to realize the lifting of the support plate 7. When the support plate 7 rises to the appropriate position, the test tube 13 will be pushed to the opening of the box body 1, facilitating the user to take and place. When taking and placing the test tube 13, the user only needs to gently slide the test tube 13 out of the support plate 7, and then put a new test tube 13 or put the taken-out test tube 13 back again. Since the test tube 13 is slidably connected to both the support plate 7 and the heat preservation block 6, the user can easily take and place the test tube 13 alone without moving other test tubes 13. After completing the taking and placing of the test tube 13, the user can rotate the handwheel 12 again to lower the support plate 7 to an appropriate position. Then, the user can cover the lid 4 back on the box body 1, and the sliding block 16 directly slides into the fixed block 15 through the triangular clamping block 21, making the clamping block 21 re-enter the slot of the sliding block 16 to realize the locking of the lid 4.

[0029] Finally, it should be noted that the above are only the preferred embodiments of the present utility model and are not used to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.

Claims

1. A liquid nitrogen freezing box for tissue anatomical sampling, comprising a box body (1), a manipulation box (2) is fixedly connected to the lower part of the box body (1), and a bottom plate (3) is fixedly connected to the lower part of the manipulation box (2), and it is characterized in that: Inside the box body (1), a heat preservation block (6) is fixedly connected. Inside the box body (1), a support plate (7) is slidably connected. Inside the support plate (7), a plurality of test tubes (13) are slidably connected. The test tubes (13) are slidably connected inside the heat preservation block (6). The upper part of the box body (1) abuts against a box cover (4). The lower part of the box cover (4) is fixedly connected with a heat preservation layer (5). The heat preservation layer (5) abuts against the upper parts of the test tubes (13). A plurality of threaded tubes (8) are height-connected to the lower part of the support plate (7). A driving component is arranged inside the operation box (2).

2. The liquid nitrogen storage box for tissue dissection sampling according to claim 1, wherein: The driving component includes a worm (11). The worm (11) is rotatably connected inside the operation box (2). A threaded rod (9) is threadedly connected inside the threaded tube (8). The threaded tube (8) is slidably connected inside the heat preservation block (6). The threaded rod (9) is rotatably connected to the upper part of the bottom plate (3). The lower part of the threaded rod (9) is fixedly connected with a worm gear (10). The worm gear (10) meshes with the worm (11). A hand wheel (12) is fixedly connected inside the worm (11).

3. The liquid nitrogen cryopreservation box for tissue dissection sampling according to claim 2, characterized in that: Two fixing blocks (15) are fixedly connected to the outside of the box body (1). A slider (16) is slidably connected inside the fixing block (15). The slider (16) is fixedly connected to one side of the box cover (4). A fixing component is arranged inside the fixing block (15).

4. A liquid nitrogen cryopreservation box for tissue anatomical sampling according to claim 3, characterized in that: The fixing component includes a clamping block (21). The clamping block (21) is slidably connected inside the slider (16). One side of the clamping block (21) is fixedly connected with a connecting plate (20). The outside of the connecting plate (20) is fixedly connected with a connecting rod (19). The outside of the connecting rod (19) is fixedly connected with a sliding plate (17). A compression spring (23) is fixedly connected between the connecting rod (19) and the fixing block (15).

5. A liquid nitrogen cryopreservation box for tissue anatomical sampling according to claim 4, characterized in that: A limiting rod (22) is fixedly connected inside the fixing block (15). The connecting rod (19) is slidably connected to the outer circumference of the limiting rod (22). The compression spring (23) is sleeved on the outer circumference of the limiting rod (22).

6. A liquid nitrogen cryopreservation box for tissue dissection sampling according to claim 1, characterized in that: A plurality of positioning columns (18) are fixedly connected to the lower part of the box cover (4). The positioning columns (18) are slidably connected inside the box body (1).

7. A liquid nitrogen freezing box for tissue dissection sampling according to claim 1, characterized in that: A grip groove (14) is formed in the upper part of the box cover (4).

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