Low-speed horizontal centrifugal machine for collecting high-capacity urine cells

By designing a low-speed horizontal centrifuge for large-capacity urine cell collection and fixing the centrifuge tube with clamping units and butterfly bolts, the cell loss problem caused by multiple centrifugation is solved, and efficient cell collection and stable separation is achieved.

CN223184717UActive Publication Date: 2025-08-05河北明志康华生物科技有限公司
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Patent Information

Application Number
CN202422308244.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-23
Publication Date
2025-08-05
Estimated Expiration
2034-09-23

AI Technical Summary

Technical Problem

When handling large-capacity urine samples, existing centrifuges require multiple centrifugation operations, resulting in cell loss and insufficient clamping force, affecting the separation effect.

Method used

A low-speed horizontal centrifuge for large-capacity urine cell collection was designed, by increasing the centrifugal capacity and fixing the centrifuge tube with clamping units and butterfly bolts, combined with the bulge of the tray to provide lateral force balance to avoid damage to the centrifuge tube and leakage.

Benefits of technology

The centrifugal collection is achieved for a few or one-time centrifugal collection, which improves the efficiency of cell collection in urine samples, reduces cell loss, increases the number of cell collection, and improves the stability of centrifugal separation.

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Abstract

The low-speed horizontal centrifugal machine comprises a machine body, a centrifugal support is in transmission connection with an inner cavity of the machine body, a plurality of clamping units are fixedly connected to the peripheral side of the centrifugal support, a centrifugal tube is clamped between every two adjacent clamping units, a protrusion is arranged at the bottom end of each centrifugal tube in an abutting mode, and a tray is fixedly connected to the bottom face of each protrusion. The tray is fixedly connected with the centrifugal bracket; the clamping unit comprises a fixing assembly and a clamping assembly, the clamping assembly comprises a first pipe clamp and a second pipe clamp, one end of the first pipe clamp is hinged to one end of the second pipe clamp through a pin shaft, the other end of the first pipe clamp and the other end of the second pipe clamp are fixedly connected with mounting plates respectively, and the two mounting plates are in threaded connection with each other; the outer side of the first pipe clamp and the outer side of the second pipe clamp are fixedly connected with supporting rods correspondingly. According to the utility model, the centrifugal capacity is increased to realize less-time or one-time centrifugal collection, so that the urine sample cell collection efficiency can be effectively improved, the cell loss is avoided, and the cell collection quantity is increased.
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Description

Technical Field

[0001] The utility model relates to the technical field of centrifugation, in particular to a low-speed horizontal centrifuge for collecting large-capacity urine cells. Background Art

[0002] Currently, most urine cells in China are collected by centrifugation, and most centrifuges have a single tube capacity of 30-50mL. The capacity of a single urine sample used for cell staining is usually 200-300mL. If a 50mL capacity centrifuge is used, multiple centrifugation cycles are required. Urine is a trace cell sample, and multiple decanting of the supernatant can easily cause cell loss, resulting in a small amount of cells collected, which affects the subsequent cell staining and histochemistry results. In addition, increasing the capacity of the centrifuge tube will increase the centrifugal pressure, resulting in insufficient clamping force for the centrifuge tube, affecting the effect of centrifugal separation. Therefore, there is an urgent need for a low-speed horizontal centrifuge for large-capacity urine cell collection to solve the above problems. Utility Model Content

[0003] In order to solve the above technical problems, the present invention proposes a low-speed horizontal centrifuge for collecting large-capacity urine cells. By increasing the centrifugal capacity, the present invention can achieve fewer or one centrifugal collections, effectively improving the efficiency of urine sample cell collection, avoiding cell loss, and increasing the number of collected cells.

[0004] To achieve the above purpose, the present invention provides the following solutions:

[0005] A low-speed horizontal centrifuge for collecting large-capacity urine cells comprises a body, an inner cavity of the body is transmission-connected to a centrifugal support, a plurality of clamping units are fixedly connected to the circumference of the centrifugal support, a centrifuge tube is clamped between adjacent clamping units, a protrusion is provided at the bottom end of the centrifuge tube, a tray is fixedly connected to the bottom surface of the protrusion, and the tray is fixedly connected to the centrifuge support; the clamping unit comprises a fixing assembly and a clamping assembly, the clamping assembly comprises a first tube clamp and a second tube clamp, one end of the first tube clamp and one end of the second tube clamp are hingedly connected by a pin, the other end of the first tube clamp and the other end of the second tube clamp are respectively fixedly connected to a mounting plate, the two mounting plates are penetrated by a butterfly bolt, and the butterfly bolt is screwed with a nut; the outer side of the first tube clamp and the outer side of the second tube clamp are respectively fixedly connected to a support rod, and the support rod is detachably connected to the fixing assembly.

[0006] Preferably, the centrifugal support includes a central shaft and several support plates, one end of all the support plates are fixedly connected to each other and formed as one piece, the top end of the central shaft passes through one end of the support plate and is fixedly connected to the support plate, the bottom end of the central shaft is transmission-connected to the centrifuge; the other end of the support plate is fixedly connected to the fixed assembly.

[0007] Preferably, the fixing assembly includes a fixing plate, which is divided into a fixing section and two mounting sections, one side of the fixing section is fixedly connected to the other end of the support plate, and one end of the two mounting sections is fixedly connected to the two ends of the fixing section at an angle and formed as one piece; a groove is provided on the top surface of the mounting section, and two clips are provided on the top surface of the groove, and the two clips are fixedly installed on both sides of the groove by a number of hexagon socket bolts; a connecting piece is fixedly connected between the two clips, and the connecting piece is detachably connected to the support rod.

[0008] Preferably, the groove is adapted to the support rod.

[0009] Preferably, a telescopic rod is fixedly connected to one side surface of the fixed section, a sliding hole is opened at the other end of the support plate, a first flange ring is fixedly connected to one end of the inner wall of the sliding hole, a second flange ring is sleeved and fixedly connected to the outer side surface of one end of the telescopic rod, the inner wall of the first flange ring is slidably connected to the outer side surface of the telescopic rod, and the outer side surface of the second flange ring is slidably connected to the inner wall of the sliding hole.

[0010] Preferably, a spring is fixedly connected between an end surface of the telescopic rod close to the second flange ring and an end surface of the sliding hole.

[0011] Preferably, the protrusion is made of elastic rubber, silicone or polyurethane.

[0012] Compared with the prior art, the present invention has the following advantages and technical effects:

[0013] The utility model utilizes two clamping units to secure the centrifuge tube, facilitating centrifugal operation of large-capacity centrifuge tubes. Meanwhile, butterfly bolts are used to tighten the outer side of the centrifuge tube, reducing the use of conventional tools and improving work efficiency. Furthermore, the tray utilizes protrusions to balance the lateral force at the bottom of the centrifuge tube, preventing damage or leakage to the centrifuge tube due to increased torque at the bottom when the centrifuge tube is subjected to centrifugal force. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] The accompanying drawings, which constitute part of this application, are intended to provide a further understanding of this application. The exemplary embodiments and descriptions of this application are intended to explain this application and do not constitute an improper limitation on this application. In the accompanying drawings:

[0015] Figure 1 This is a side view schematic diagram of the three-dimensional structure of the utility model;

[0016] Figure 2 This is a structural diagram of the centrifugal support and the clamping unit of the utility model;

[0017] Figure 3 It is a schematic diagram of the side structure of the clamping assembly;

[0018] Figure 4 Schematic diagram of the cross-sectional structure of the telescopic rod and the support plate;

[0019] Figure 5 It is a schematic diagram of the three-dimensional structure of the centrifugal bracket from the side;

[0020] Among them, 1. body; 2. centrifugal bracket; 21. central axis; 22. support plate; 3. centrifuge tube; 4. protrusion; 5. tray; 6. first pipe clamp; 7. second pipe clamp; 8. pin; 9. mounting plate; 10. butterfly bolt; 11. nut; 12. support rod; 13. fixing plate; 14. groove; 15. clip; 16. connecting plate; 17. telescopic rod; 18. sliding hole; 19. first flange ring; 20. second flange ring; 30. spring. DETAILED DESCRIPTION

[0021] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments in this application can be combined with each other. The present application will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0022] It should be noted that all components in the technical solution of this application require necessary additional facilities for water supply, oil supply, electricity supply and gas supply for driving and / or control. If there is no further explanation, it is assumed that the existing technology is used and equipped, and no special explanation is required.

[0023] It should be noted that, in order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below with reference to the accompanying drawings and specific implementation methods.

[0024] Depend on Figure 1 The shown low-speed horizontal centrifuge for collecting large-capacity urine cells includes a body 1, an inner cavity of the body 1 is transmission-connected to a centrifugal support 2, a plurality of clamping units are fixedly connected to the circumference of the centrifugal support 2, a centrifuge tube 3 is clamped between adjacent clamping units, the bottom end of the centrifuge tube 3 is abutted with a protrusion 4, the bottom surface of the protrusion 4 is fixedly connected to a tray 5, and the tray 5 is fixedly connected to the centrifuge support 2; the clamping unit includes a fixing assembly and a clamping assembly, the clamping assembly includes a first tube clamp 6 and a second tube clamp 7, one end of the first tube clamp 6 and one end of the second tube clamp 7 are hingedly connected by a pin 8, the other end of the first tube clamp 6 and the other end of the second tube clamp 7 are respectively fixedly connected to a mounting plate 9, the two mounting plates 9 are penetrated by a butterfly bolt 10, the butterfly bolt 10 is screwed with a nut 11, and the mounting plate 9 is clamped between the butterfly bolt 10 and the nut 11 for fixing the first tube clamp 6 and the second tube clamp 7, and the butterfly bolt 10 can facilitate the rapid opening and closing of the first tube clamp 6 and the second tube clamp 7. Support rods 12 are fixedly connected to the outer sides of the first pipe clamp 6 and the second pipe clamp 7 respectively. The support rods 12 are detachably connected to the fixing assembly.

[0025] A further optimized solution is that the centrifugal support 2 includes a central shaft 21 and a plurality of support plates 22. One end of each support plate 22 is fixedly connected to each other and integrally formed. The top end of the central shaft 21 passes through one end of the support plate 22 and is fixedly connected to the support plate 22. The bottom end of the central shaft 21 is transmission-connected to the centrifuge. The centrifuge can provide driving force to the central shaft 21 through an internal drive mechanism to drive it to rotate. This is prior art and will not be described in detail here. The other end of the support plate 22 is fixedly connected to a fixed assembly.

[0026] Further optimization scheme, the fixing assembly includes a fixing plate 13, the fixing plate 13 is divided into a fixing section and two mounting sections, the fixing plate 13 and the support frame 2 form a plum blossom-shaped structure, which is convenient for fixing the centrifuge tube 3. One side of the fixing section is fixedly connected to the other end of the support plate 22, and one end of the two mounting sections is fixedly connected to the two ends of the fixing section at an angle and integrally formed; the top surface of the mounting section is provided with a groove 14, and the groove 14 is adapted to the support rod 12. The top surface of the groove 14 is provided with two clips 15, and the two clips 15 are fixedly installed on both sides of the groove 14 by a number of hexagon socket bolts; a connecting piece 16 is fixedly connected between the two clips 15, and the connecting piece 16 is detachably connected to the support rod 12. By removing any one of the clips 15, the connecting piece 16 can be opened to facilitate the installation of the support rod 12.

[0027] In a further optimized solution, the telescopic rod 17 is fixedly connected to one side of the fixed section, and a sliding hole 18 is defined at the other end of the support plate 22. A first flange ring 19 is fixedly connected to one end of the inner wall of the sliding hole 18. A second flange ring 20 is sleeved and fixedly connected to the outer side of one end of the telescopic rod 17. The inner wall of the first flange ring 19 is slidably connected to the outer side of the telescopic rod 17, and the outer side of the second flange ring 20 is slidably connected to the inner wall of the sliding hole 18. A spring 30 is fixedly connected between the end surface of the telescopic rod 17 near the second flange ring 20 and the end surface of the sliding hole 18. The detachable connection between the first flange ring 19 and the second flange ring 20 limits the sliding movement of the telescopic rod 17 within the support plate 22. At the same time, the spring 30 pre-tightens the telescopic rod 17 to prevent it from sliding freely and affecting the balance of the centrifugal stand 2.

[0028] According to a further optimization scheme, the protrusion 4 is made of elastic rubber, silicone or polyurethane. The protrusion 4 balances the lateral force of the centrifuge tube 3 during the centrifugation process through the friction with the centrifuge tube 3, thereby reducing the probability of damage or leakage of the centrifuge tube 3.

[0029] The working process of this embodiment is as follows:

[0030] The present invention primarily comprises a centrifuge body, a centrifuge stand 2, a first tube clamp 6, a second tube clamp 7, and a butterfly bolt 10. First, a 100 mL urine sample is placed into an assembled urine slab centrifuge tube 3, and the lid is tightened. The upper edges of the first and second tube clamps 6 and 7 are then positioned against the lower edge of the tube cap of the centrifuge tube 3. The tube clamp is then secured with the butterfly bolt 10, ensuring that the centrifuge tube 3 does not fall out of the clamping assembly during centrifugation.

[0031] Then place the clamping assembly carrying the centrifuge tube 3 into the groove at one end of the centrifuge bracket 2, open one of the clips 14, insert the support rod 12 into the groove, press the connecting piece 16 onto the support rod 12, and tighten the clip 14 to prevent the tube from detaching from the centrifuge during the centrifugation process.

[0032] Note that before centrifugation, the centrifuge tube 3 containing the sample needs to be leveled or the same volume of sample needs to be added. Centrifuge at 3500 rpm for 10 minutes. After centrifugation, release the fixing assembly and remove the clamping assembly along with the centrifuge tube. Without removing the clamping assembly, simply pour out the liquid in the centrifuge tube and inject the remaining sample into the centrifuge tube 3. Repeat the above steps. Repeat multiple times if the cell count is low.

[0033] After centrifugation is completed, the clamping assembly is disassembled and obvious cell sediment can be seen at the bottom of the centrifuge tube 3, which can be used for subsequent cell smear or other diagnosis.

[0034] The above are merely preferred embodiments of the present application, but the scope of protection of the present application is not limited thereto. Any changes or substitutions that can be easily conceived by a person skilled in the art within the technical scope disclosed in this application should be included in the scope of protection of the present application. Therefore, the scope of protection of the present application should be based on the scope of protection of the claims.

Claims

1. A low-speed horizontal centrifuge for large-volume urine cell collection, characterized in that: The invention comprises a machine body (1), wherein the inner cavity of the machine body (1) is connected to a centrifugal support (2) in a transmission manner, a plurality of clamping units are fixedly connected to the peripheral side of the centrifugal support (2), a centrifugal tube (3) is clamped between adjacent clamping units, a protrusion (4) is provided at the bottom end of the centrifugal tube (3), a tray (5) is fixedly connected to the bottom surface of the protrusion (4), and the tray (5) is fixedly connected to the centrifugal support (2); the clamping unit comprises a fixing assembly and a clamping assembly, and the clamping assembly comprises a first tube clamp (6) and a second tube clamp (7). One end of the first pipe clamp (6) and one end of the second pipe clamp (7) are hinged via a pin shaft (8); the other end of the first pipe clamp (6) and the other end of the second pipe clamp (7) are respectively fixedly connected with a mounting plate (9); butterfly bolts (10) pass through the two mounting plates (9); the butterfly bolts (10) are screwed with nuts (11); the outer sides of the first pipe clamp (6) and the outer sides of the second pipe clamp (7) are respectively fixedly connected with support rods (12), and the support rods (12) are detachably connected to the fixing assembly.

2. The low-speed horizontal centrifuge for large-capacity urine cell collection according to claim 1, characterized in that: The centrifuge support (2) comprises a central shaft (21) and a plurality of support plates (22), one end of each of the support plates (22) being fixedly connected to each other and integrally formed, the top end of the central shaft (21) passing through one end of the support plate (22) and being fixedly connected to the support plate (22), the bottom end of the central shaft (21) being transmission-connected to the centrifuge; and the other end of the support plate (22) being fixedly connected to the fixing assembly.

3. The low-speed horizontal centrifuge for large-capacity urine cell collection according to claim 2, characterized in that: The fixing assembly comprises a fixing plate (13), the fixing plate (13) is divided into a fixing section and two mounting sections, one side of the fixing section is fixedly connected to the other end of the support plate (22), one end of the two mounting sections is fixedly connected to the two ends of the fixing section at an angle and is integrally formed; a groove (14) is provided on the top surface of the mounting section, two clips (15) are provided on the top surface of the groove (14), and the two clips (15) are fixedly installed on both sides of the groove (14) by a plurality of hexagon socket bolts; a connecting piece (16) is fixedly connected between the two clips (15), and the connecting piece (16) is detachably connected to the support rod (12).

4. The low-speed horizontal centrifuge for large-capacity urine cell collection according to claim 3, characterized in that: The groove (14) is adapted to the support rod (12).

5. The low-speed horizontal centrifuge for large-capacity urine cell collection according to claim 3, characterized in that: A telescopic rod (17) is fixedly connected to one side of the fixed section, a sliding hole (18) is opened at the other end of the support plate (22), a first flange ring (19) is fixedly connected to one end of the inner wall of the sliding hole (18), a second flange ring (20) is sleeved and fixedly connected to the outer side of one end of the telescopic rod (17), the inner wall of the first flange ring (19) is slidably connected to the outer side of the telescopic rod (17), and the outer side of the second flange ring (20) is slidably connected to the inner wall of the sliding hole (18).

6. The low-speed horizontal centrifuge for large-capacity urine cell collection according to claim 5, characterized in that: A spring (30) is fixedly connected between an end surface of the telescopic rod (17) close to the second flange ring (20) and an end surface of the sliding hole (18).

7. The low-speed horizontal centrifuge for large-capacity urine cell collection according to claim 1, characterized in that: The protrusion (4) is made of elastic rubber, silicone or polyurethane.