Sample concentration device

Abstract

The utility model relates to a sample concentration device, which comprises a base, a supporting structure, a fixing structure and an air blowing part used for blowing dry air, a containing groove is arranged in the base, the air blowing part is arranged in the containing groove, the supporting structure is arranged on the base, and the fixing structure is arranged on the base. The fixing structure is installed over the base through the supporting structure and located within the working range of the air blowing part, the fixing structure comprises a plurality of clamping assemblies arranged at intervals, each clamping assembly comprises a clamping part, and each clamping part is provided with a clamping groove allowing a dialysis bag containing samples to stretch into and be fixed. According to the sample concentration device provided by the utility model, the problem that the concentration efficiency and the experiment cost cannot be considered at the same time in the existing concentration equipment is solved.

Description

Technical Field

[0001] The utility model relates to the technical field of experimental equipment, in particular to a sample concentrating device. Background Art

[0002] During experiments, protein samples of varying concentrations are used, requiring sample concentration. Currently, the most common method involves placing the dialysis bag containing the sample directly on the test bench and using a fan to blow through it, but this method has low concentration efficiency. Using ultrafiltration tubing in conjunction with centrifugal equipment for sample concentration is faster, but can be cumbersome when processing large numbers of samples. Furthermore, the wear and tear of the ultrafiltration tubing can lead to relatively high costs. Utility Model Content

[0003] The main purpose of the utility model is to provide a sample concentration device, aiming to solve the problem that existing concentration equipment cannot take into account both concentration efficiency and experimental cost.

[0004] To achieve the above-mentioned objectives, the present invention proposes a sample concentrator device, comprising a base, a supporting structure, a fixing structure, and a blowing portion for blowing out dry air. The base is provided with a receiving groove, the blowing portion is arranged in the receiving groove, the supporting structure is arranged on the base, the fixing structure is installed directly above the base through the supporting structure, and is within the operating range of the blowing portion. The fixing structure includes a plurality of spaced-apart clamping assemblies, the clamping assembly includes a clamping portion, and the clamping portion has a fixed clamping groove for a dialysis bag containing a sample to extend into.

[0005] According to some embodiments of the present invention, the supporting structure includes a shell, which is arranged on the base. An installation cavity connected to the accommodating groove and an air outlet is provided in the shell. The installation cavity is connected to the outside world through the air outlet, and the fixing structure is arranged in the installation cavity.

[0006] According to some embodiments of the present invention, a heating portion is further included, and the heating portion is disposed in the receiving tank and is located on the wind path of the blowing portion.

[0007] According to some embodiments of the present invention, the shell is made of a transparent material.

[0008] According to some embodiments of the present invention, a mounting assembly connected to the supporting structure is further included, the fixed structure is connected to the supporting structure via the mounting assembly, and each of the clamping assemblies is movably mounted on the mounting assembly.

[0009] According to some embodiments of the present invention, the mounting assembly includes a first connecting part and a second connecting part, the first connecting part is connected to the supporting structure, the clamping assembly is connected to the first connecting part through the second connecting part, and the clamping assembly is movably arranged in the x direction relative to the first connecting part.

[0010] According to some embodiments of the present invention, the second connecting portion is movably mounted on the first connecting portion along the x-direction, and the clamping assembly is movably mounted on the second connecting portion along the y-direction.

[0011] According to some embodiments of the present invention, the clamping assembly is rotatably mounted on the second connecting portion, and the axis direction of rotation of the clamping assembly is perpendicular to the extension direction of the second connecting portion.

[0012] According to some embodiments of the present invention, the clamping assembly further includes a clamping seat, the clamping portion is rotatably mounted on the clamping seat, and the clamping end of the clamping portion can cooperate with the end face of the clamping seat to form the clamping groove.

[0013] According to some embodiments of the present invention, an air guide portion capable of guiding the wind direction of the blowing portion is further included, and the air guide portion covers the notch of the accommodating slot.

[0014] The utility model has at least the following beneficial effects:

[0015] In the present invention, a receiving groove is provided in the base, the blowing part is provided in the receiving groove, the supporting structure is provided on the base, the fixing structure is installed directly above the base through the supporting structure, and is within the operating range of the blowing part, the fixing structure includes a plurality of clamping assemblies arranged at intervals, the clamping assembly includes a clamping part, and the clamping part has a fixed clamping groove for the dialysis bag containing the sample to extend into. The experimenter first fixes a plurality of dialysis bags containing samples on the clamping assemblies respectively, and then turns on the blowing part, which blows dry air to the dialysis bag. On the one hand, the moisture in the sample is transferred to the dry air through the osmotic pressure principle, and on the other hand, the evaporation of the moisture in the liquid sample in the dialysis bag is accelerated by accelerating the air flow rate near the dialysis bag, thereby concentrating the sample. Compared to the prior art method of placing the dialysis bag containing the sample directly on the test bench and using a fan to blow directly, which can only blow to one side of the dialysis bag, the present application has the clamping assembly suspended directly above the base, and the clamping assemblies are spaced apart, so that the blowing part can speed up the air flow rate in various parts of the dialysis bag, and adopts a blowing part that can blow out dry air, thereby accelerating the evaporation of water in the sample and improving the concentration efficiency of the sample; at the same time, compared to using ultrafiltration tubes in conjunction with centrifugal equipment to concentrate the sample, the present application does not need to use consumables such as ultrafiltration tubes, and the experimental cost is lower. The sample concentration device provided by the utility model solves the problem that the existing concentration equipment cannot take into account both concentration efficiency and experimental cost. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0017] Figure 1 A schematic structural diagram of a sample concentrator provided in an embodiment of the present utility model;

[0018] Figure 2 for Figure 1 Top view of the sample concentrator in Figure 2.

[0019] Description of reference numerals:

[0020] 100-sample concentrator; 1-base; 11-accommodating tank; 2-support structure; 21-housing; 3-fixing structure; 31-clamping assembly; 311-clamping portion; 312-clamping seat; 4-blowing portion; 5-heating portion; 6-installation assembly; 61-first connecting portion; 62-second connecting portion; 7-air guide portion. DETAILED DESCRIPTION

[0021] The following is a clear and complete description of the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0022] It should be noted that if the embodiments of the present invention involve directional indications (such as up, down, left, right, front, back, etc.), the directional indications are only used to explain the relative position relationship, movement status, etc. between the various components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indications will also change accordingly.

[0023] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present invention, the descriptions of "first", "second", etc. are only for descriptive purposes and cannot be understood as indicating or suggesting their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of such features. In addition, the meaning of "and / or" appearing throughout the text includes three parallel schemes. Taking "A and / or B" as an example, it includes scheme A, or scheme B, or a scheme in which A and B are satisfied at the same time. In addition, the technical solutions between the various embodiments can be combined with each other, but it must be based on the ability of ordinary technicians in this field to implement. When the combination of technical solutions is mutually contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.

[0024] The utility model provides a concentrating device. Figures 1 to 2 This is a specific embodiment of a concentration device provided by the utility model.

[0025] like Figure 1 and Figure 2 As shown, an embodiment of the present invention provides a sample concentrator 100, comprising a base 1, a support structure 2, a fixed structure 3, and a blowing portion 4 for blowing out dry air. The base 1 is provided with a receiving groove 11, the blowing portion 4 is disposed in the receiving groove 11, the support structure 2 is disposed on the base 1, the fixed structure 3 is mounted directly above the base 1 through the support structure 2, and is within the operating range of the blowing portion 4, the fixed structure 3 includes a plurality of spaced-apart clamping assemblies 31, the clamping assembly 31 includes a clamping portion 311, and the clamping portion 311 has a clamping groove for a dialysis bag containing a sample to extend into and fix.

[0026] In the present invention, a receiving groove 11 is provided in the base 1, the blowing part 4 is provided in the receiving groove 11, the supporting structure 2 is provided on the base 1, the fixing structure 3 is installed directly above the base 1 through the supporting structure 2, and is within the operating range of the blowing part 4, the fixing structure 3 includes a plurality of clamping assemblies 31 arranged at intervals, the clamping assembly 31 includes a clamping part 311, and the clamping part 311 has a fixed clamping groove for a dialysis bag containing a sample to extend into. The experimenter first fixes a plurality of dialysis bags containing samples on the clamping assembly 31 respectively, and then turns on the blowing part 4, which blows dry air to the dialysis bag. On the one hand, the moisture in the sample is transferred to the dry air through the osmotic pressure principle, and on the other hand, the evaporation of the moisture in the liquid sample in the dialysis bag is accelerated by accelerating the air flow rate near the dialysis bag, thereby concentrating the sample. Compared to the prior art method of placing the dialysis bag containing the sample directly on the test bench and using a fan to blow directly, which can only blow to one side of the dialysis bag, the present application has the clamping assembly 31 suspended directly above the base 1, and the clamping assemblies 31 are spaced apart, so that the blowing part 4 can speed up the air flow rate in various parts of the dialysis bag, and adopts a blowing part 4 that can blow out dry air, thereby accelerating the evaporation of water in the sample and improving the concentration efficiency of the sample; at the same time, compared to using ultrafiltration tubes in conjunction with centrifugal equipment to concentrate the sample, the present application does not need to use consumables such as ultrafiltration tubes, and the experimental cost is lower. The sample concentration device 100 provided by the utility model solves the problem that the existing concentration equipment cannot take into account both concentration efficiency and experimental cost.

[0027] It should be noted that the blowing unit 4 is actually a dehumidifier.

[0028] Since the dialysis bag is directly exposed to the external environment and is easily affected by the external temperature and humidity, in some embodiments, Figure 1 As shown, the support structure 2 includes a shell 21, which is arranged on the base 1. The shell 21 is provided with a mounting cavity connected to the receiving tank 11 and an air outlet. The mounting cavity is connected to the outside world through the air outlet, and the fixing structure 3 is arranged in the mounting cavity. In this way, the shell 21 can, on the one hand, separate the dialysis bag from the external environment to prevent it from being excessively affected by external temperature and humidity, and allows the dry air blown out by the blowing part 4 to contact the sample in the dialysis bag for a longer time, thereby improving the sample concentration efficiency. On the other hand, it can protect the dialysis bag.

[0029] Preferably, in order to achieve controllable temperature in the housing 21 and improve the concentration efficiency of the sample, in some embodiments, as Figure 1As shown, the sample concentrator 100 further includes a heating unit 5, which is disposed within the receiving tank 11 and in the air path of the blowing unit 4. With this arrangement, when the outside temperature is low, the air blown by the blowing unit 4 is converted into warm air by the heating unit 5, thereby raising the temperature within the installation chamber and maintaining it within the optimal temperature range of approximately 37 degrees Celsius, thereby improving sample concentration efficiency.

[0030] Since the experimenter needs to turn off the blowing part 4 after the sample in the dialysis bag is concentrated to the required concentration to avoid over-concentration of the sample, in some embodiments, the material of the housing 21 is transparent. In this way, the transparent housing 21 allows the experimenter to observe the sample in the dialysis bag in real time to avoid over-concentration.

[0031] Since the wind force at different positions in the blowing range of the blowing part 4 is different, the sample concentration speed is different. Therefore, in some embodiments, Figure 1 and Figure 2 As shown, the sample concentrator 100 further includes a mounting assembly 6 connected to the support structure 2. The fixed structure 3 is connected to the support structure 2 via the mounting assembly 6, and each of the clamping assemblies 31 is movably mounted on the mounting assembly 6. This arrangement allows the clamping assemblies 31 to be movably mounted on the mounting assembly 6, allowing the experimenter to adjust the position of the clamping assemblies 31 according to actual needs, thereby changing the concentration rate of samples at different positions, thereby improving the applicability of the sample concentrator 100.

[0032] Furthermore, the specific structure of the mounting assembly 6 is not limited, as long as each of the clamping assemblies 31 is movably mounted on the mounting assembly 6. For example, in some embodiments, Figure 1 and Figure 2 As shown, the mounting assembly 6 includes a first connecting portion 61 and a second connecting portion 62. The first connecting portion 61 is connected to the support structure 2, and the clamping assembly 31 is connected to the first connecting portion 61 via the second connecting portion 62. The clamping assembly 31 is movable in the x-direction relative to the first connecting portion 61. This arrangement allows experimenters to increase the number of clamping assemblies 31 and adjust the spacing between the multiple clamping assemblies 31 in the x-direction according to actual conditions, allowing the sample concentrator 100 to simultaneously concentrate more samples and improve overall concentration efficiency.

[0033] In some embodiments, as Figure 1 and Figure 2As shown, the second connecting portion 62 is movably mounted on the first connecting portion 61 along the x-direction, and the clamping assembly 31 is movably mounted on the second connecting portion 62 along the y-direction. This arrangement allows the experimenter to adjust the spacing between the multiple clamping assemblies 31 in the y-direction. When the dialysis bag is large, two clamping assemblies 31 can be used to jointly secure a dialysis bag, allowing the sample concentrator 100 to accommodate dialysis bags of a wider range of sizes, thereby improving the applicability of the sample concentrator 100.

[0034] Furthermore, in some embodiments, Figure 1 As shown, the clamping assembly 31 is rotatably mounted on the second connecting portion 62, with the axis of rotation of the clamping assembly 31 being perpendicular to the extension direction of the second connecting portion 62. This arrangement allows the two clamping assemblies 31 in both the x- and y-directions to cooperate and secure a dialysis bag, allowing the sample concentrator 100 to accommodate dialysis bags of a wider variety of sizes, thereby enhancing the applicability of the sample concentrator 100.

[0035] Specifically, in some embodiments, Figure 1 As shown, the clamping assembly 31 also includes a clamping seat 212. The clamping portion 311 is rotatably mounted on the clamping seat 212. The clamping end of the clamping portion 311 can cooperate with the end surface of the clamping seat 212 to form the clamping groove. In this arrangement, the clamping portion 311 cooperates with the end surface of the clamping seat 212 to form the clamping groove to clamp the dialysis bag. Compared to the prior art method of providing two clamping portions 311, which are close to each other to clamp the filter paper, the structure is simpler.

[0036] Since the wind force at different positions of the blowing part 4 is different, in order to improve the concentration efficiency, the experimenter needs to specifically adjust the position of the clamping assembly 31. Therefore, in some embodiments, as shown in FIG. Figure 1 As shown, the sample concentrator 100 further includes an air guide 7 for directing the air flow from the air blowing portion 4. The air guide 7 covers the opening of the receiving slot 11. By providing the air guide 7 to change the air flow direction of the air blowing portion 4, the experimenter does not need to adjust the position of each clamping assembly 31, thereby improving experimental efficiency.

[0037] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A sample concentrator, characterized in that: The invention comprises a base, a supporting structure, a fixing structure and a blowing part for blowing out dry air. The base is provided with a receiving groove, the blowing part is arranged in the receiving groove, the supporting structure is arranged on the base, the fixing structure is installed directly above the base through the supporting structure, and is within the operating range of the blowing part. The fixing structure comprises a plurality of clamping assemblies arranged at intervals, the clamping assembly comprises a clamping part, and the clamping part has a fixed clamping groove for a dialysis bag containing a sample to extend into.

2. The sample concentrator according to claim 1, wherein The supporting structure includes a shell, which is arranged on the base. The shell is provided with an installation cavity connected to the accommodating groove and an air outlet. The installation cavity is connected to the outside world through the air outlet. The fixing structure is arranged in the installation cavity.

3. The sample concentrator according to claim 2, wherein: It also includes a heating part, which is arranged in the containing tank and is located on the wind path of the blowing part.

4. The sample concentrator according to claim 2, wherein: The shell is made of transparent material.

5. The sample concentrator according to claim 1, wherein It also includes a mounting assembly connected to the support structure, the fixed structure is connected to the support structure through the mounting assembly, and each of the clamping assemblies is movably mounted on the mounting assembly.

6. The sample concentrator according to claim 5, wherein: The mounting assembly includes a first connecting portion and a second connecting portion, the first connecting portion is connected to the supporting structure, the clamping assembly is connected to the first connecting portion via the second connecting portion, and the clamping assembly is movably arranged relative to the first connecting portion in the x direction.

7. The sample concentrator according to claim 6, wherein: The second connecting portion is movably mounted on the first connecting portion along the x-direction, and the clamping assembly is movably mounted on the second connecting portion along the y-direction.

8. The sample concentrator according to claim 6, wherein: The clamping assembly is rotatably mounted on the second connecting portion, and the axis direction of the clamping assembly is perpendicular to the extending direction of the second connecting portion.

9. The sample concentrator according to claim 1, wherein: The clamping assembly further comprises a clamping seat, the clamping portion is rotatably mounted on the clamping seat, and the clamping end of the clamping portion can cooperate with the end surface of the clamping seat to form the clamping groove.

10. The sample concentrator according to claim 1, wherein: It also includes an air guide portion that can guide the wind direction of the blowing portion, and the air guide portion covers the notch of the accommodating slot.

Images