Equipment for removing endotoxin from animal serum

By designing an animal serum endotoxin removal equipment and using the combined action of twisted dragon and stirred leaves, the complicated process of activated carbon and endotoxin adsorption materials in the existing technology was solved, and efficient endotoxin removal effect was achieved.

CN223209044UActive Publication Date: 2025-08-12SHANGHAI XINZEMU BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422518205.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-17
Publication Date
2025-08-12
Estimated Expiration
2034-10-17

AI Technical Summary

Technical Problem

In the prior art, endotoxins exist in animal serum, and it is necessary to use activated carbon and endotoxin adsorption materials for adsorption treatment before filtering, but the process is cumbersome and inefficient.

Method used

An animal serum endotoxin removal equipment was designed, and the animal serum and activated carbon were mixed by motor drive, and combined with stirred leaves to stir endotoxin adsorption materials and serum to achieve efficient adsorption and filtration.

Benefits of technology

It has achieved efficient removal of endotoxins from animal serum, simplified the operation process and improved the processing efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides animal serum endotoxin removing equipment, and particularly relates to the technical field of animal serum, the animal serum endotoxin removing equipment comprises a barrel body and a barrel cover, the top of the barrel cover is fixedly connected with a first injection pipe, according to the animal serum endotoxin removing equipment, animal serum is put into the first injection pipe, then activated carbon is put into a second injection pipe, and the first injection pipe and the second injection pipe are connected. A first motor drives a packing auger to rotate, so that animal serum and activated carbon are better mixed and mixed for a long time, the animal serum is subjected to activated carbon impurity removal and adsorption, then an electric cylinder is started, the animal serum subjected to impurity removal is discharged from a discharging port, a first filter screen can isolate the activated carbon, an endotoxin adsorption material is put in through a third injection pipe, and the animal serum is subjected to impurity removal and adsorption. Then the animal serum is mixed with the animal serum subjected to impurity removal, stirring is conducted through the stirring blades, the effect of removing the toxin in the animal serum is completed, the control valve is opened, and the qualified animal serum is discharged from the discharging pipe.
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Description

Technical Field

[0001] The utility model relates to the technical field of animal serum, in particular to an animal serum endotoxin removal device. Background Art

[0002] Animal serum is the most widely used natural culture medium in cell culture. It is rich in nutrients necessary for cell growth and is often used for in vitro culture of animal cells. It has extremely important functions. It provides hormones that maintain cell exponential growth, nutrients that are absent or present in very small amounts in the basal culture medium, and major low-molecular nutrients. It can also provide binding proteins that can recognize vitamins, lipids, metals and other hormones, and can bind to or modulate the activity of the substances they bind to. Endotoxins exist in animal serum. When removing endotoxins, it is necessary to use activated carbon and endotoxin adsorption materials for adsorption treatment, and then filter after adsorption. Utility Model Content

[0003] The purpose of the present invention is to provide an animal serum endotoxin removal device to solve the problem that endotoxins exist in animal serum and that endotoxin removal requires adsorption treatment using activated carbon and endotoxin adsorption materials, followed by filtration after adsorption.

[0004] To achieve the above-mentioned objectives, the utility model provides the following technical solutions: an animal serum endotoxin removal device, comprising a barrel body and a barrel cover, the top of the barrel cover is fixedly connected to a first injection pipe, the top of the barrel cover is fixedly connected to a second injection pipe, the inner side of the barrel body is provided with a filtering mechanism, the filtering mechanism comprises a hopper, a first filter screen, a baffle, a chute, a discharge port, a slide plate, an electric cylinder, a first motor and an auger, the inner side of the barrel body is fixedly connected to the hopper, the inner side of the hopper is fixedly connected to the first filter screen, the bottom of the hopper is fixedly connected to the baffle, the inner side of the baffle is provided with a chute, the inner side of the chute is provided with a discharge port, the inner side of the chute is slidably connected to the slide plate, one side of the slide plate is fixedly connected to the electric cylinder, the top of the barrel cover is fixedly connected to the first motor, one end of the output shaft of the first motor is fixedly connected to the auger, and the inner side of the barrel body is provided with a stirring mechanism.

[0005] Preferably, a third filter is placed inside the first injection pipe.

[0006] Preferably, the discharge port is communicated with the hopper.

[0007] Preferably, the stirring mechanism includes a third injection pipe, a second motor, a fixed shaft, a stirring blade, a feed pipe, a control valve, a second filter and a discharge pipe. The third injection pipe is fixedly connected to the outside of the barrel body, the second motor is fixedly connected to the bottom of the barrel body, one end of the output shaft of the second motor is fixedly connected to the fixed shaft, the outside of the fixed shaft is fixedly connected to the stirring blade, the bottom of the barrel body is connected to the feed pipe, one end of the feed pipe is connected to the control valve, the other end of the feed pipe is fixedly connected to the second filter, and the bottom of the outer side of the barrel body is fixedly connected to the discharge pipe.

[0008] Preferably, the third injection pipe is connected to the barrel body.

[0009] Preferably, the discharge pipe is connected to the barrel body.

[0010] Compared with the prior art, the beneficial effects of the utility model are as follows: when using the animal serum endotoxin removal equipment, the animal serum is placed in the first injection pipe, and then the activated carbon is placed in the second injection pipe, and the auger is driven to rotate by the first motor to better mix the animal serum and the activated carbon, and the mixture is mixed for a long time, so that the animal serum is subjected to activated carbon impurity removal and adsorption, and then the electric cylinder is started to discharge the animal serum after impurity removal from the discharge port, and the first filter can isolate the activated carbon, and the endotoxin adsorption material is placed through the third injection pipe and then mixed with the animal serum after impurity removal, and stirred by the stirring blade to complete the effect of removing endotoxins from the animal serum, and the control valve is opened, and the qualified animal serum is discharged from the discharge pipe, and the control valve is closed, and then the barrel cover is opened, the activated carbon is taken out, and the inside of the barrel body is rinsed, and the valve on the discharge pipe is opened, and the endotoxin adsorption material is discharged through the discharge pipe to complete the cleaning. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 This is a schematic diagram of the appearance structure of the connector of the utility model;

[0012] Figure 2 This is a schematic diagram of the structure of the first injection pipe and the second injection pipe cooperating with each other in the present utility model;

[0013] Figure 3 This is a schematic diagram of the structure of the mutual cooperation between the feed port and the slide plate of the utility model;

[0014] Figure 4 This is a schematic diagram of the structure of the mutual cooperation between the feed pipe and the control valve of the utility model;

[0015] Figure 5 This is a schematic diagram of the structure of the first injection pipe and the third filter screen cooperating with each other in the present utility model.

[0016] In the figure: 1. barrel body; 2. barrel cover; 3. first injection pipe; 4. second injection pipe; 5. filtering mechanism; 501. hopper; 502. first filter screen; 503. baffle; 504. chute; 505. discharge port; 506. slide plate; 507. electric cylinder; 508. first motor; 509. auger; 6. stirring mechanism; 601. third injection pipe; 602. second motor; 603. fixed shaft; 604. stirring blade; 605. discharge pipe; 606. control valve; 607. second filter screen; 608. discharge pipe; 7. third filter screen. DETAILED DESCRIPTION

[0017] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0018] It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification for people familiar with this technology to understand and read, and are not used to limit the conditions under which this application can be implemented. Therefore, they have no substantive technical significance. Any structural modification, change in proportional relationship or adjustment of size should still fall within the scope of the technical content disclosed in this application without affecting the efficacy and purpose that can be achieved by this application.

[0019] Example

[0020] See also Figure 1-5The utility model is an animal serum endotoxin removal device: it includes a barrel body 1 and a barrel cover 2, the top of the barrel cover 2 is fixedly connected to a first injection pipe 3, the top of the barrel cover 2 is fixedly connected to a second injection pipe 4, the inner side of the barrel body 1 is provided with a filtering mechanism 5, the filtering mechanism 5 includes a hopper 501, a first filter screen 502, a baffle 503, a chute 504, a discharge port 505, a slide plate 506, an electric cylinder 507, a first motor 508 and an auger 509, the inner side of the barrel body 1 is fixedly connected to the hopper 501, the inner side of the hopper 501 is fixedly connected to the first filter screen 502, the bottom of the hopper 501 is fixedly connected to the baffle 503, the inner side of the baffle 503 is provided with a chute 504, the inner side of the chute 504 is provided with a discharge port 505, 5. A slide plate 506 is slidably connected to the inner side of the slide 504, and an electric cylinder 507 is fixedly connected to one side of the slide plate 506. A first motor 508 is fixedly connected to the top of the barrel cover 2, and one end of the output shaft of the first motor 508 is fixedly connected to an auger 509. A stirring mechanism 6 is provided on the inner side of the barrel body 1. When in use, the animal serum is put into the first injection tube 3, and then the activated carbon is put into the second injection tube 4. The auger 509 is driven to rotate by the first motor 508 to better mix the animal serum and the activated carbon. The mixture is mixed for a long time, so that the animal serum is adsorbed by the activated carbon to remove impurities. Then the electric cylinder 507 is started to discharge the animal serum after impurities removal from the discharge port 505, and the first filter screen 502 can isolate the activated carbon.

[0021] Furthermore, a third filter screen 7 is placed inside the first injection pipe 3 .

[0022] Furthermore, the discharge port 505 is connected to the hopper 501 .

[0023] In order to facilitate the adsorption of endotoxins, the stirring mechanism 6 includes a third injection pipe 601, a second motor 602, a fixed shaft 603, a stirring blade 604, a discharge pipe 605, a control valve 606, a second filter 607 and a discharge pipe 608. The outer side of the barrel body 1 is fixedly connected to the third injection pipe 601, the bottom of the barrel body 1 is fixedly connected to the second motor 602, one end of the output shaft of the second motor 602 is fixedly connected to the fixed shaft 603, the outer side of the fixed shaft 603 is fixedly connected to the stirring blade 604, the bottom of the barrel body 1 is connected to the discharge pipe 605, one end of the discharge pipe 605 is connected to the control valve 606, and the discharge pipe 608 is fixedly connected to the second motor 602. The other end of the tube 605 is fixedly connected to a second filter screen 607, and the outer bottom of the barrel body 1 is fixedly connected to a discharge pipe 608. The endotoxin adsorption material is put in through the third injection pipe 601, and then mixed with the animal serum that has been removed from the impurities, and stirred by the stirring blade 604 to complete the effect of removing endotoxins from the animal serum. The control valve 606 is opened, and the qualified animal serum is discharged from the discharge pipe 605. The control valve 606 is closed, and then the barrel cover 2 is opened, the activated carbon is taken out, and the inside of the barrel body 1 is rinsed. The valve on the discharge pipe 608 is opened, and the endotoxin adsorption material is discharged through the discharge pipe 608 to complete the cleaning.

[0024] Furthermore, the third injection pipe 601 is connected to the barrel body 1.

[0025] Furthermore, the discharge pipe 608 is connected to the barrel body 1.

[0026] Working principle: When in use, put the animal serum into the first injection tube 3, and then put the activated carbon into the second injection tube 4, and drive the auger 509 to rotate through the first motor 508 to better mix the animal serum and activated carbon, and mix them for a long time to remove impurities from the animal serum by activated carbon adsorption, and then start the electric cylinder 507 to discharge the animal serum after impurities removal from the discharge port 505, and the first filter 502 can isolate the activated carbon, and put the endotoxin adsorption material through the third injection tube 601, and then mix it with the animal serum after impurities removal, and stir it through the stirring blade 604 to complete the effect of removing endotoxins from the animal serum, open the control valve 606, and the qualified animal serum is discharged from the discharge pipe 605, close the control valve 606, and then open the barrel cover 2, take out the activated carbon, and rinse the inside of the barrel body 1, open the valve on the discharge pipe 608, and the endotoxin adsorption material is discharged through the discharge pipe 608 to complete the cleaning.

[0027] Although the embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these implementation rules without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An animal serum endotoxin removal device, comprising a barrel (1) and a barrel cover (2), characterized in that: The top of the barrel cover (2) is fixedly connected to a first injection pipe (3), the top of the barrel cover (2) is fixedly connected to a second injection pipe (4), the inner side of the barrel body (1) is provided with a filtering mechanism (5), the filtering mechanism (5) comprises a hopper (501), a first filter screen (502), a baffle (503), a chute (504), a discharge port (505), a slide plate (506), an electric cylinder (507), a first motor (508) and an auger (509), the inner side of the barrel body (1) is fixedly connected to a hopper (501), the inner side of the hopper (501) is fixedly connected to the first filter screen ( 502), a baffle (503) is fixedly connected to the bottom of the hopper (501), a chute (504) is provided on the inner side of the baffle (503), a discharge port (505) is provided on the inner side of the chute (504), a slide (506) is slidably connected to the inner side of the chute (504), an electric cylinder (507) is fixedly connected to one side of the slide (506), a first motor (508) is fixedly connected to the top of the barrel cover (2), an auger (509) is fixedly connected to one end of the output shaft of the first motor (508), and a stirring mechanism (6) is provided on the inner side of the barrel body (1).

2. The animal serum endotoxin removal device according to claim 1, characterized in that: A third filter screen (7) is placed inside the first injection pipe (3).

3. The animal serum endotoxin removal device according to claim 1, characterized in that: The discharge port (505) is communicated with the hopper (501).

4. The animal serum endotoxin removal device according to claim 1, characterized in that: The stirring mechanism (6) comprises a third injection pipe (601), a second motor (602), a fixed shaft (603), a stirring blade (604), a discharge pipe (605), a control valve (606), a second filter (607) and a discharge pipe (608). The outer side of the barrel body (1) is fixedly connected to the third injection pipe (601), the bottom of the barrel body (1) is fixedly connected to the second motor (602), one end of the output shaft of the second motor (602) is fixedly connected to the fixed shaft (603), the outer side of the fixed shaft (603) is fixedly connected to the stirring blade (604), the bottom of the barrel body (1) is connected to the discharge pipe (605), one end of the discharge pipe (605) is connected to the control valve (606), the other end of the discharge pipe (605) is fixedly connected to the second filter (607), and the outer bottom of the barrel body (1) is fixedly connected to the discharge pipe (608).

5. The animal serum endotoxin removal device according to claim 4, characterized in that: The third injection pipe (601) is connected to the barrel body (1).

6. The animal serum endotoxin removal device according to claim 4, characterized in that: The discharge pipe (608) is connected to the barrel body (1).