Cleaning disc capable of conducting negative pressure cleaning on liquid injection and suction needles
By moving the cleaning tank from the lower part of the cleaning plate to the top and adopting a negative pressure design, the problem of excessive length and stroke of the needle body when cleaning the injection and liquid aspiration needle is solved, and more efficient cleaning effect and detection stability are achieved, simplifying the structure and operation of the cleaning tank.
Patent Information
- Application Number
- CN202422187119.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-06
- Publication Date
- 2025-08-15
- Estimated Expiration
- 2034-09-06
AI Technical Summary
When cleaning the existing cleaning plates, the needle length and downward movement stroke are too long when cleaning the injection and liquid aspiration needles, which affects the stability and efficiency of the detection operation.
Move the cleaning tank from the lower part of the cleaning plate to the top, adopt the negative pressure cleaning tank design, and seal the injection and liquid aspiration needle through the valve and the cylinder through hole, shorten the needle body length and downward movement stroke, and form a negative pressure state in the cleaning tank to prevent the leakage of cleaning water.
The needle body length and downward stroke of the injection and suction needles are shortened, and the factors influencing the detection operation are reduced, ensuring the cleaning effect and normal progress of the inspection, and simplifying the structure and disassembly and assembly process of the cleaning tank.
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Figure CN223222135U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a cleaning disk, in particular to a cleaning disk capable of performing negative pressure cleaning of injection and aspiration needles in a full-automatic single molecule immunoassay device, belonging to the technical field of medical inspection. Background Art
[0002] Since the first automated chemical analyzer was manufactured, over half a century has passed, and fully automated immunoassay analyzers have reached technological maturity. Today's fully automated immunoassay analyzers feature the following: 1. They utilize a multi-degree-of-freedom robotic arm to coordinate the movements of various modules; 2. They offer exceptional flexibility, enabling them to meet diverse analytical needs; 3. They offer rapid testing speeds and long, unattended, continuous operation times; and 4. Their integration of multiple technologies and fully automated processing yield more accurate and precise test results. Fully automated immunoassay analyzers handle all steps of the experimental testing process, including cuvette removal, sample addition, reaction solution addition, shaking, reaction initiation, measurement, analysis, and cleaning. By replacing manual labor, they not only save labor costs but, more importantly, eliminate human error and ensure data accuracy. With their speed, efficiency, high precision, and repeatability, fully automated immunoassay analyzers are widely used in processing, production, testing, and life support, and are poised to become a trend in medical testing.
[0003] During the test, nanomagnetic beads are used to bind to antibodies and antigens. After binding, the remaining liquid in the reaction cuvette must be cleaned to ensure detection results. The principle of magnetic separation and cleaning is as follows: in the enzyme-catalyzed chemiluminescent immunoassay technique, the cloned antibodies in the magnetic bead reagent react with the analyte in the sample, as well as the enzyme-labeled antibody or antigen in the reagent, through a nonspecific immune reaction, forming a magnetic immune complex that is suspended in the reaction system. In the magnetic field created by the magnet, the magnetic immune complex and unbound magnetic particles are quickly captured and attached to the area near the magnetic field. Liquid outside the magnetic particle complex is removed, separating the magnetic particle complex from the enzyme particles in the liquid. When the external magnetic field is removed and cleaning fluid is injected, the magnetic particle complex is evenly dispersed in the solution, completing the removal of free enzymes. The magnetic beads, acting as a reaction carrier for the antigen and antibody, have a suspending property that enables the immune reaction to occur quickly and uniformly, while also promoting the rapid separation of the immune complex from the solution.
[0004] In immunoassay analyzers, a cleaning tray is responsible for cleaning the cuvettes. During the cleaning process, the cuvettes undergo a repeated cycle of "injection, cleaning, and aspiration" before being sent to the next step for testing. Existing techniques present a problem: after a period of downtime, the injection and aspiration needles in the cleaning tray need to be cleaned. However, existing cleaning trays can only use the injection and aspiration needles to clean the magnetic beads in the cuvettes. Cleaning the injection and aspiration needles themselves requires complex steps and results in poor cleaning results.
[0005] The applicant submitted an invention patent application in 2023, with publication number CN116984298A and publication date November 3, 2023. The patent document discloses a method for cleaning the injection and aspiration needles in the cleaning tray of an immunoassay analyzer, wherein a cleaning tank is arranged inside the cleaning tray below the turntable; during normal operation, the injection needle and the aspiration needle are controlled to move downward and inserted into the reaction cup on the turntable to clean the reaction cup; when the injection and aspiration needles need to be cleaned, the reaction cup is first removed, and then the injection needle and the aspiration needle are controlled to move downward so that the injection needle and the aspiration needle pass through the turntable and are inserted into the cleaning tank for cleaning the injection needle and the aspiration needle.
[0006] In this patent document, the cleaning tank is located at the lower part of the cleaning tray. When cleaning the injection needle and the pipetting needle, it is necessary to control the injection needle and the pipetting needle to move downward and insert them into the cleaning tank for cleaning. Therefore, the needle body length of the injection and pipetting needles and the downward movement stroke of the injection and pipetting needles will be relatively long, which may cause some problems affecting the detection operation.
[0007] Therefore, how to redesign a cleaning tray so that it can shorten the needle body length and downward movement stroke of the injection and pipette needles when cleaning them, thereby reducing the probability of factors affecting the detection operation, is a technical problem that needs to be solved urgently. Utility Model Content
[0008] The technical problem to be solved by the present invention is to address the defects existing in the prior art and provide a cleaning tray that can perform negative pressure cleaning of injection and pipetting needles. When the injection and pipetting needles are cleaned, the length of the needle body of the injection and pipetting needles and the downward movement stroke of the injection and pipetting needles can be shortened, thereby reducing the probability of occurrence of factors affecting the detection operation.
[0009] In order to solve the above technical problems, the technical solution adopted by the utility model is: a cleaning disk capable of performing negative pressure cleaning of injection and aspiration needles, comprising a cleaning disk cylinder, a turntable mechanism arranged inside the cleaning disk cylinder and a needle lifting mechanism arranged above the cleaning disk cylinder, the injection needle and the aspiration needle are both arranged on the needle lifting mechanism, the reaction cup is placed on the turntable of the turntable mechanism, and the reaction cup can be driven to rotate by the turntable, and a negative pressure cleaning tank is provided on the top of the cleaning disk cylinder and below the needle lifting mechanism. Driven by the needle lifting mechanism, the injection needle and the aspiration needle can be moved down and inserted into the negative pressure cleaning tank for cleaning, and can also be moved down through the negative pressure cleaning tank and inserted into the reaction cup for normal detection.
[0010] Preferably, a pair of through holes is provided on the cleaning tank and located below each injection needle and aspiration needle; the pair of through holes includes an upper hole provided on the top surface of the cleaning tank and a lower hole provided on the bottom surface of the cleaning tank, and a valve is provided at the opening of each upper hole and lower hole; a cylinder through hole is provided on the top of the cleaning disk cylinder and located at the position of each pair of through holes;
[0011] When the injection needle and the pipetting needle are inserted into the reaction cup, they are inserted into the reaction cup after passing through the valve of the upper hole of the perforation, the valve of the lower hole of the perforation and the cylinder through hole on the top of the cleaning disk cylinder in sequence.
[0012] Preferably, a water inlet joint is provided on one end of the cleaning tank, and a water outlet joint is provided on the other end of the cleaning tank, the water inlet joint is connected to pump one, and the water outlet joint is connected to pump two.
[0013] Preferably, the cleaning tank includes a fully enclosed arc-shaped tank body and a tank flange arranged on one side of the arc-shaped tank body. The cleaning tank is screwed into the top of the cleaning disc cylinder by installing a screw through the tank flange, thereby setting the cleaning tank on the top of the cleaning disc cylinder.
[0014] Preferably, a cleaning chamber is provided in the arc-shaped trough body, and the water inlet joint and the water outlet joint are respectively provided at both ends of the arc-shaped trough body and both the water inlet joint and the water outlet joint are connected to the cleaning chamber, the upper hole is provided at the top of the arc-shaped trough body, and the lower hole is provided at the bottom of the arc-shaped trough body, and both the upper hole and the lower hole are connected to the cleaning chamber.
[0015] Preferably, the upper hole and the lower hole are both configured as countersunk holes, and the valve is disposed in the countersunk-shaped upper hole and the lower hole.
[0016] Preferably, a cleaning disc partition is provided inside the cleaning disc cylinder, and the cleaning disc partition divides the interior of the cleaning disc cylinder into an upper cylinder space located at the upper position and a lower cylinder space located at the lower position; the turntable of the turntable mechanism is located in the upper cylinder space, and insulation material and a heating device are provided inside the upper cylinder space.
[0017] Preferably, the heating device adopts an electric heating film.
[0018] The beneficial effects of the present invention are as follows: by moving the cleaning tank upwards, the present invention shortens the needle length of the injection and aspiration needle and the downward movement of the injection and aspiration needle when performing the cleaning operation of the injection and aspiration needle itself, compared with the prior art, thereby reducing the probability of factors affecting the detection operation; in addition, by designing the cleaning tank to be in a negative pressure state, when the injection and aspiration needle pass through the cleaning tank, there will be no problem of cleaning water leakage, thereby ensuring the normal progress of the detection operation. By designing the specific structure of the cleaning tank, the volume of the cleaning chamber is made smaller, which makes it easier to form a negative pressure state in a smaller cleaning chamber. The cleaning tank is only provided with a one-in and one-out structure, which makes the cleaning tank structure in the present invention simpler. The cleaning tank is mounted to the outside of the cleaning disk cylinder by screws, which makes it easier to disassemble and assemble the cleaning tank. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 This is a schematic diagram of the axial cross-sectional structure of the cleaning disc in the embodiment of the present utility model;
[0020] Figure 2 Schematic diagram of the three-dimensional structure of the cleaning tank in the cleaning tray of the utility model Figure 1 ;
[0021] Figure 3 Schematic diagram of the three-dimensional structure of the cleaning tank in the cleaning tray of the utility model Figure 2 ;
[0022] Figure 4 for Figure 2 A schematic diagram of the enlarged structure of the middle part A;
[0023] Figure 5 for Figure 1 A schematic diagram of a partial axial cross-sectional structure located at a through hole of a cylinder;
[0024] Figure 6 This is a schematic diagram of a partial axial cross-sectional structure of a cleaning tray in an embodiment of the present utility model when an injection needle is inserted into a reaction cup;
[0025] Figure 7 This is a schematic diagram of a partial axial cross-sectional structure of a cleaning disk in an embodiment of the present utility model when cleaning an injection needle;
[0026] Figure 8 This is a schematic diagram of a partial axial cross-sectional structure of a cleaning plate in an embodiment of the present utility model when cleaning the inner wall of a pipette needle;
[0027] Figure 9 This is a schematic diagram of a partial axial cross-sectional structure of a cleaning plate in an embodiment of the utility model when cleaning the outer wall of a liquid pipette needle. Figure 1 ;
[0028] Figure 10 This is a schematic diagram of a partial axial cross-sectional structure of a cleaning plate in an embodiment of the utility model when cleaning the outer wall of a liquid pipette needle. Figure 2 .
[0029] In the figure: 1. Cleaning disk cylinder, 111. Cylinder through hole, 112. Cleaning disk partition, 2. Turntable mechanism, 211. Turntable, 212. Turntable motor and reducer, 3. Needle lifting mechanism, 4. Reaction cup, 5. Cleaning tank, 511. Tank body, 512. Tank body flange, 513. Cleaning chamber, 6. Injection needle, 7. Aspiration needle, 8. Through hole, 811. Upper hole, 812. Lower hole, 9. Valve, 10. Water inlet connector, 11. Water outlet connector. DETAILED DESCRIPTION
[0030] The technical solution of the present utility model is further described in detail below with reference to the accompanying drawings and specific embodiments.
[0031] In order to shorten the needle body length of the injection and pipetting needles and the downward stroke of the injection and pipetting needles, the applicant moved the original cleaning tank from the bottom of the cleaning tray to the top of the cleaning tray, and carried out the work of cleaning the needle body in the cleaning tank on the top of the cleaning tray. This shortened the needle body length of the injection and pipetting needles and the downward stroke of the injection and pipetting needles. However, after moving to the top of the cleaning tray, the cleaning tank is located between the injection and pipetting needles and the reaction cup. When performing the detection operation, the injection and pipetting needles located at the upper position need to be moved downward and inserted into the reaction cup. At this time, the cleaning tank is located between the injection and pipetting needles and the reaction cup. When the injection and pipetting needles move downward, they need to pass through the cleaning tank to be inserted into the reaction cup. There is cleaning water in the cleaning tank. Therefore, the cleaning tank needs to be improved to ensure that the cleaning water will not leak out when the injection and pipetting needles pass through the cleaning tank.
[0032] Example: Figure 1As shown, the cleaning tray includes a cleaning tray body 1, a turntable mechanism 2 disposed inside the cleaning tray body 1, and a needle lifting mechanism 3 disposed above the cleaning tray body 1; a reaction cup 4 is placed on a turntable 211 of the turntable mechanism 2, which drives the reaction cup 4 to rotate. A closed cleaning tank 5 is disposed on the top of the cleaning tray body 1 and below the needle lifting mechanism 3. Both the injection needle 6 and the aspiration needle 7 are disposed on the needle lifting mechanism 3. Figure 2 and Figure 3 As shown, since the injection needles and the pipette needles are distributed circumferentially of the turntable, the closed cleaning tank 5 is correspondingly arranged in an arc shape, and a pair of through holes 8 are provided on the cleaning tank 5 and below each injection needle 6 and pipette needle 7. In this embodiment, three injection needles 6 and three pipette needles 7 are provided, so a total of six pair of through holes 8 are provided in the cleaning tank 5. The pair of through holes 8 include an upper hole 811 provided on the top surface of the cleaning tank 5 and a lower hole 812 provided on the bottom surface of the cleaning tank 5, as shown in FIG. Figure 4 As shown, a valve 9 is provided at the opening of each upper hole 811 and lower hole 812. The valve 9 is made of silicone material and has a cross slit in the middle, thus forming a petal shape to facilitate the needle to pass through. Figure 2 and Figure 3 As shown, a water inlet joint 10 is provided on one end of the cleaning tank 5, and a water outlet joint 11 is provided on the other end of the cleaning tank 5. The water inlet joint 10 is connected to pump 1 (not shown in the figure), and the water outlet joint 11 is connected to pump 2 (not shown in the figure). Pump 1 is used to send cleaning water and air into the cleaning tank 5, and pump 2 is used to extract the cleaning water and air in the cleaning tank 5. Pump 2 can form a certain negative pressure in the cleaning tank 5, so that through the cooperation of the above-mentioned pump 1 and pump 2, the cleaning water circulates between the cleaning tank 5 and the outside world and the cleaning tank 5 can form a certain negative pressure state. The negative pressure state and the cooperation between the needle body and the valve can prevent the cleaning water from flowing out of the cleaning tank 5. It should be noted here that the cleaning tank 5 is not completely filled with cleaning water. Since the outside air will also be sent into the cleaning tank 5, the cleaning tank 5 is in a mixed state of air and cleaning liquid. In addition, as Figure 5 As shown, in order to facilitate the insertion of the needle into the reaction cup, a cylinder through hole 111 is opened on the top of the cleaning disk cylinder 1 and at the position of each through hole 8.
[0033] like Figure 6As shown, the cleaning method of the injection and aspiration needles in the cleaning disk is that during normal detection work, driven by the downward movement of the needle body lifting mechanism, the injection needle 6 and the aspiration needle 7 can descend and sequentially pass through the valve 9 of the upper hole 811 of the perforation, the valve 9 of the lower hole 812 of the perforation and the cylinder through hole 111 on the top of the cleaning disk cylinder 1, and then be inserted into the reaction cup 4 to clean the reaction cup; when the injection and aspiration needles need to be cleaned, it is only necessary to control the downward movement of the needle body lifting mechanism so that the injection needle and the aspiration needle are inserted into the cleaning tank from the perforation on the cleaning tank for cleaning.
[0034] When the needle passes through the valve, a sealing structure is formed between the needle and the valve. Since the cleaning water in the cleaning tank flows rapidly and the cleaning tank is in a negative pressure state, the cleaning water in the cleaning tank will not leak out from the valve, thereby avoiding the occurrence of cleaning water leakage problems.
[0035] Therefore, this embodiment moves the cleaning tank upward. Compared with the existing technology, when performing the cleaning operation of the injection and pipetting needles themselves, the needle body length of the injection and pipetting needles and the downward movement stroke of the injection and pipetting needles are shortened, thereby reducing the probability of factors affecting the detection operation; in addition, by designing the cleaning tank to be in a negative pressure state, when the injection and pipetting needles pass through the cleaning tank, there will be no problem of cleaning water leakage, thereby ensuring the normal progress of the detection operation.
[0036] Therefore, if Figure 2 and Figure 5As shown, the cleaning tank 5 includes a fully enclosed arcuate tank body 511 and a tank flange 512 disposed on one side of the arcuate tank body 511. The cleaning tank 5 is screwed onto the top of the cleaning disc body 1 via a mounting screw (not shown) passing through the tank flange 512, thereby placing the cleaning tank 5 on the top of the cleaning disc body 1. A cleaning chamber 513 is disposed within the arcuate tank body 511. An inlet connector 10 and an outlet connector 11 are disposed at opposite ends of the arcuate tank body 511, both of which are in communication with the cleaning chamber 513. The upper hole 811 is disposed at the top of the arcuate tank body 511, and the lower hole 812 is disposed at the bottom of the arcuate tank body 511. Both the upper hole 811 and the lower hole 812 are in communication with the cleaning chamber 513. Both the upper hole 811 and the lower hole 812 are configured as countersunk holes, and the valve 9 is disposed in the countersunk upper hole 811 and the lower hole 812. Since the cleaning tank 5 in this embodiment is relatively small in size, it is two-thirds smaller than the cleaning tank in the patent document mentioned in the background art. The above-mentioned arrangement makes the volume of the cleaning chamber 513 even smaller, which makes it easier to form a negative pressure state in the smaller cleaning chamber 513. In addition, the cleaning tank in the prior art is provided with multiple water inlets, while the cleaning tank in this embodiment is only provided with a single inlet and a single outlet, making the cleaning tank structure in this embodiment simpler. The cleaning tank in the prior art is installed inside the cleaning disc body, which is very inconvenient when the cleaning tank needs to be disassembled. The cleaning tank in this embodiment is installed on the top of the cleaning disc body 1 by screws, located outside the cleaning disc body 1, making it easier to disassemble and assemble the cleaning tank.
[0037] During routine work, when cleaning the magnetic beads in the reaction cup using a cleaning tray, when using an injection needle to inject liquid into the reaction cup, since the injection needle is inserted into the liquid in the reaction cup, when cleaning the injection needle, only the inner wall of the injection needle needs to be cleaned; and when using a pipette needle to aspirate liquid into the reaction cup, since the pipette needle needs to be inserted into the liquid in the reaction cup, when cleaning the pipette needle, both the inner and outer walls of the pipette needle need to be cleaned. In the prior art, when cleaning the injection needle and the pipette needle, the needle body is inserted into the cleaning tank and then left stationary for cleaning. This cleaning method, especially when cleaning the outer wall of the pipette needle, can often only clean a small distance, and the cleaning effect is not very good.
[0038] In this embodiment, since the position and structure of the cleaning tank are changed, the cleaning steps are also changed. The cleaning method of the injection and aspiration needles in this embodiment includes an injection needle cleaning method and a aspiration needle cleaning method. The specific steps of the injection needle cleaning method are as follows:
[0039] When negative pressure is formed in the cleaning chamber 513 of the cleaning tank:
[0040] 1) If Figure 7 As shown, the needle lifting mechanism is controlled to descend, so that the injection needle 6 is inserted into the cleaning chamber 513 from the upper hole 811 perforated on the cleaning tank, and then the needle lifting mechanism is stopped;
[0041] 2) Control the injection needle 6 to start injecting cleaning water, and the cleaning water is injected into the cleaning chamber 513. Finally, the cleaning water is pumped away through the water outlet joint, so that the inner wall of the injection needle 6 is cleaned by the cleaning water flowing through the injection needle 6, thereby improving the cleaning effect.
[0042] The method for cleaning the liquid-absorbing needle includes a method for cleaning the inner wall of the needle body and a method for cleaning the outer wall of the needle body. The specific steps of the method for cleaning the inner wall of the needle body of the liquid-absorbing needle are as follows:
[0043] When negative pressure is formed in the cleaning chamber 513 of the cleaning tank:
[0044] A1: If Figure 8 As shown, the needle lifting mechanism is controlled to descend, so that the liquid-absorbing needle 7 is inserted into the cleaning water in the cleaning chamber 513 from the upper hole 811 perforated on the cleaning tank, and then the needle lifting mechanism is stopped;
[0045] A2: Control the liquid-absorbing needle 7 to start absorbing cleaning water. Part of the cleaning water is absorbed by the liquid-absorbing needle 7, and the other part of the cleaning water is drawn out through the water outlet joint, so that the inner wall of the liquid-absorbing needle 7 is cleaned by the cleaning water flowing through the liquid-absorbing needle 7.
[0046] The specific steps of the method for cleaning the outer wall of the needle body of the liquid-absorbing needle are as follows:
[0047] When negative pressure is formed in the cleaning chamber 513 of the cleaning tank:
[0048] B1: If Figure 9 and Figure 10 As shown, the needle lifting mechanism is controlled to descend, so that the liquid-absorbing needle 7 is inserted into the cleaning cavity 513 from the upper hole 811 of the cleaning tank, and then continues to pass through the lower hole 812 of the cleaning tank from the cleaning cavity 513;
[0049] B2: Then control the needle lifting mechanism to rise, driving the liquid aspiration needle 7 from the lower hole 812 perforated on the cleaning tank back into the cleaning chamber 513;
[0050] B3: Then repeat steps B1 and B2 until the outer wall of the needle is cleaned;
[0051] After the outer wall of the needle body is cleaned, the needle body lifting mechanism is controlled to rise, driving the liquid-absorbing needle 7 to be drawn out from the upper hole 811 of the cleaning tank.
[0052] It should be noted that, in this embodiment, the cleaning of the inner and outer walls of the aspiration needle are generally carried out separately. This is because when cleaning the outer wall of the needle body, the aspiration needle needs to be controlled to stop aspirating liquid. This can avoid the problem of unstable negative pressure in the cleaning tank being sucked away by the aspiration needle during the up and down movement of the aspiration needle, thereby preventing the aspiration needle from sucking away part of the cleaning water and air in the cleaning tank.
[0053] When cleaning the outer wall of the pipette needle, this embodiment is carried out by controlling the pipette needle to rise and fall repeatedly in coordination with the cleaning water in the cleaning tank. In this way, the length of the outer wall of the pipette needle to be cleaned can be determined by controlling the stroke of the pipette needle to rise and fall, so that this embodiment can select the length of the outer wall of the pipette needle to be cleaned according to actual working conditions, which is more practical.
[0054] like Figure 1 As shown, a wash disc partition 112 is disposed within the wash disc cylinder 1. This partition 112 divides the interior of the wash disc cylinder 1 into an upper cylinder space located at the top and a lower cylinder space located at the bottom. The turntable 211 of the turntable mechanism 2 is located within the upper cylinder space. Insulating material and a heating device (not shown) are disposed within the upper cylinder space. The heating device utilizes an electric heating film. The insulating material and heating device heat the interior of the upper cylinder space and maintain a constant temperature. This is because a reaction cup must maintain a certain operating temperature after being placed on the turntable. This embodiment, by locating the turntable within the insulating space of the upper cylinder space, ensures that the reaction cups on the turntable are always maintained at a constant operating temperature.
[0055] The turntable mechanism 2 further includes a turntable motor and reducer 212, which are mounted on the cleaning disk partition 112. The rotating shaft 6121 of the turntable motor and reducer 612 extends into the space of the upper cylinder and is connected to the turntable 211. In the prior art, the turntable is driven by a belt drive, which results in a complex transmission structure and occupies a large amount of space. In this embodiment, the turntable motor, which is integrated with the reducer, is directly connected to the turntable, eliminating the belt drive structure, thereby simplifying the structure of the rotation mechanism and reducing the occupied space.
[0056] In summary, the present invention moves the cleaning tank upwards, which shortens the needle length of the injection and aspiration needle and the downward movement of the injection and aspiration needle when performing the cleaning operation of the injection and aspiration needle itself, compared with the prior art, thereby reducing the probability of factors affecting the detection operation; in addition, by designing the cleaning tank to be in a negative pressure state, when the injection and aspiration needle pass through the cleaning tank, there will be no problem of cleaning water leakage, ensuring the normal progress of the detection operation. Through the specific structural design of the cleaning tank, the volume of the cleaning chamber is made smaller, which makes it easier to form a negative pressure state in a smaller cleaning chamber. The cleaning tank is only provided with a one-in and one-out structure, which makes the cleaning tank structure in the present invention simpler. The cleaning tank is mounted to the outside of the cleaning disk cylinder by screws, which makes it easier to disassemble and assemble the cleaning tank.
[0057] The term "plurality" in this embodiment refers to "two or more." The above embodiments are intended only to illustrate the present invention and are not intended to limit the present invention. Persons skilled in the art may make various modifications or alterations without departing from the spirit and scope of the present invention. Therefore, all equivalent technical solutions are intended to fall within the scope of protection of the present invention, which is defined by the claims.
Claims
1. A cleaning tray capable of performing negative pressure cleaning on injection and aspiration needles, comprising a cleaning tray body, a turntable mechanism disposed within the cleaning tray body, and a needle lift mechanism disposed above the cleaning tray body. Both the injection and aspiration needles are disposed on the needle lift mechanism. A cuvette is placed on a turntable of the turntable mechanism, and the turntable drives the cuvette to rotate. The invention is characterized in that: A negative pressure cleaning tank is provided on the top of the cleaning disk cylinder and below the needle lifting mechanism. Driven by the needle lifting mechanism, the injection needle and the aspiration needle can be moved downward and inserted into the negative pressure cleaning tank for cleaning, or can be moved downward and passed through the negative pressure cleaning tank and inserted into the reaction cup for normal detection.
2. The cleaning tray according to claim 1, wherein: A pair of through holes is provided on the cleaning tank and located below each injection needle and aspiration needle; the pair of through holes includes an upper hole provided on the top surface of the cleaning tank and a lower hole provided on the bottom surface of the cleaning tank, and a valve is provided at the opening of each upper hole and lower hole; a cylinder through hole is provided on the top of the cleaning disk cylinder and located at the position of each pair of through holes; When the injection needle and the pipetting needle are inserted into the reaction cup, they are inserted into the reaction cup after passing through the valve of the upper hole of the perforation, the valve of the lower hole of the perforation and the cylinder through hole on the top of the cleaning disk cylinder in sequence.
3. The cleaning tray according to claim 2, wherein: A water inlet joint is provided on one end of the cleaning tank, and a water outlet joint is provided on the other end of the cleaning tank. The water inlet joint is connected to pump one, and the water outlet joint is connected to pump two.
4. The cleaning tray according to claim 3, wherein: The cleaning tank includes a fully enclosed arc-shaped tank body and a tank flange arranged on one side of the arc-shaped tank body. The cleaning tank is screwed into the top of the cleaning disc cylinder through the tank flange by installing screws, so that the cleaning tank is arranged on the top of the cleaning disc cylinder.
5. The cleaning tray according to claim 4, characterized in that: A cleaning chamber is provided in the arc-shaped trough body, and a water inlet joint and a water outlet joint are respectively provided at both ends of the arc-shaped trough body and both the water inlet joint and the water outlet joint are connected to the cleaning chamber, the upper hole is provided at the top of the arc-shaped trough body, and the lower hole is provided at the bottom of the arc-shaped trough body, and both the upper hole and the lower hole are connected to the cleaning chamber.
6. The cleaning tray according to claim 5, characterized in that: The upper hole and the lower hole are both configured as countersunk holes, and the valves are configured in the countersunk-shaped upper hole and the lower hole.
7. The cleaning tray according to any one of claims 1 to 6, characterized in that: A cleaning disc partition is provided inside the cleaning disc cylinder, which divides the interior of the cleaning disc cylinder into an upper cylinder space located at an upper position and a lower cylinder space located at a lower position; the turntable of the turntable mechanism is located in the upper cylinder space, and insulation material and a heating device are provided inside the upper cylinder space.
8. The cleaning tray according to claim 7, characterized in that: The heating device adopts an electric heating film.
Citation Information
Patent Citations
Cleaning method for liquid injection and suction needles in immunity analyzer cleaning disc and cleaning disc
CN116984298A
Cited By
Negative pressure cleaning method for liquid injection and suction needles in cleaning disc
CN119387262A