Anti-radiation IVC system for mice

Abstract

The utility model belongs to the technical field of experimental animal feeding, and particularly relates to a mouse anti-radiation IVC system which comprises a host, a cage frame and cage boxes, the host is arranged on one side of the cage frame, a plurality of cage boxes are installed on the cage frame, an illumination regulator is arranged on the cage frame, a radiation detector is installed on one side of each cage box, and the radiation detector is connected with the host. Lead plates are arranged on the side face and the bottom face of each cage box, an air supply mechanism and an air exhaust mechanism are arranged between the main machine and the cage frame, and the air supply mechanism and the air exhaust mechanism are connected with all the cage boxes respectively. The illumination regulator is arranged on the cage frame, growth of animals under natural illumination conditions can be simulated, the radiation detector is installed on one side of each cage box, the radiation condition in the living environment of mice can be monitored in real time, the lead plates are arranged on the side face and the bottom face of each cage box, and therefore the radiation condition of the mice can be monitored in real time. The experimental animal in the cage can be effectively protected from radiation interference, the accuracy of an experimental model is ensured, and data is more sufficient.

Description

Technical Field

[0001] The utility model belongs to the technical field of experimental animal breeding, and particularly relates to a mouse radiation protection IVC system. Background Art

[0002] Laboratory animal science is the foundation and important supporting condition for life science research. The IVC system (independent ventilation cage) has a truly sustainable SPF barrier environment, providing an SPF environment for small rodents, effectively preventing cross-infection and protecting experimental animals. The laboratory animal IVC system is an efficient, safe and convenient animal breeding and experimental equipment that can provide strong support for scientific researchers, promote the improvement of laboratory animal welfare and the smooth development of scientific research.

[0003] The genomes of experimental mice are highly similar to those of humans, and they also have certain similarities with humans in metabolic pathways and genetic backgrounds. Therefore, they can better simulate the human response after exposure to radiation. In the development and testing of radiation-proof drugs, researchers need to raise mice in a radiation-proof IVC system, and evaluate the impact and potential risks of radiation on the genetic material of organisms through experiments and observation of the growth and development of the offspring of experimental mice. Utility Model Content

[0004] The purpose of the utility model is to overcome the shortcomings of the existing technology and provide a mouse radiation protection IVC system to provide a clean, safe and comfortable breeding environment for experimental mice, protect the mice from radiation, and at the same time be able to monitor the radiation conditions of the environment in each cage in real time.

[0005] To achieve the above-mentioned purpose, the technical solution adopted by the present invention is: a mouse radiation protection IVC system, including a main unit, a cage frame and cage boxes, the main unit is arranged on one side of the cage frame, and several cage boxes are installed on the cage frame. A light regulator is provided on the cage frame, and a radiation detector is installed on one side of each cage box. Lead plates are provided on the side and bottom of each cage box. An air supply mechanism and an exhaust mechanism are provided between the main unit and the cage frame, and the air supply mechanism and the exhaust mechanism are respectively connected to each cage box.

[0006] Preferably, the lead plate includes a fixed lead plate, a front lead plate and a rear lead plate. The fixed lead plate is installed under the cage box. The fixed lead plate includes an integrally formed bottom plate and two side plates. Lead plate mounting grooves are provided on the front and rear sides of the fixed lead plate. The front lead plate and the rear lead plate are respectively installed in the two lead plate mounting grooves.

[0007] Preferably, a support frame is provided on the lower side of each fixed lead plate, and the support frame is fixedly provided on the cage frame.

[0008] Preferably, the thickness of the lead plate is 8 mm.

[0009] Preferably, temperature regulators are provided on both the air supply mechanism and the air exhaust mechanism.

[0010] Preferably, the air supply mechanism includes an air supply pipe, an air supply box and an air supply fan, the air outlet of the air supply fan is connected to the air supply box, one end of the air supply pipe is connected to the air supply box, the other end of the air supply pipe is respectively connected to each cage box, and a temperature regulator is installed on the air supply box; the exhaust mechanism includes an exhaust pipe, an exhaust box and an exhaust fan, the exhaust branch pipes of each cage box are connected to the exhaust box, the air inlet of the exhaust fan is connected to the exhaust box, the air outlet of the exhaust fan is connected to the exhaust pipe, and a temperature regulator is installed on the exhaust box.

[0011] Preferably, filters are provided in both the exhaust box and the supply air box.

[0012] Preferably, a plurality of independent spaces for placing cage boxes are arranged on the cage frame, guide rails are provided on both sides of each independent space, and supporting side panels are provided on both sides of each cage box, and the supporting side panels are installed on the guide rails.

[0013] Compared with the existing technology, the above technical solution has the following beneficial effects:

[0014] 1. The utility model includes a main unit, a cage frame and a cage box. A light regulator is provided on the cage frame. The light regulator can adjust the light in the growth environment of the experimental animals, effectively simulate the effects of different light conditions on the experimental animals, and at the same time simulate the growth of animals under natural light conditions. A radiation detector is installed on one side of each cage box, which can realize real-time monitoring of the radiation conditions in the living environment of the mice. Lead plates are provided on the sides and bottom of each cage box, which can effectively protect the experimental animals in the cage from radiation interference, ensure the accuracy of the experimental model, and make the data more sufficient.

[0015] 2. The temperature regulator can automatically heat the system when the ambient temperature drops, ensuring the stability of the internal temperature of the system and protecting the experimental animals. When the heating reaches the system set value, the temperature regulator stops heating to ensure the stability of the animal growth environment temperature.

[0016] 3. The purpose of setting a temperature regulator in the exhaust mechanism is because the distance between the exhaust branch pipe and the exhaust box 11 is very long. During this process, the temperature will continue to drop, thereby affecting the temperature inside the cage. Therefore, a temperature regulator is also set in the exhaust box for heating to ensure the stability of the internal temperature of the system. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a structural diagram of the present utility model.

[0018] Figure 2 This is a schematic diagram of the host structure.

[0019] Figure 3 Schematic diagram of the structure of the cage box and lead plate.

[0020] Figure 4 Schematic diagram of the structure of the lead plate.

[0021] Figure 5 It is the main view of the present utility model.

[0022] Figure 6 for Figure 5 Enlarged view of point A in the middle.

[0023] Figure 7 This is a structural diagram of the guide rail.

[0024] Among them: 1. host 2. cage frame 3. cage box 4. host screen 5. exhaust duct 6. air supply duct 7. alarm light 8. casters 9. air supply box 10. air supply fan 11. exhaust box 12. exhaust fan 13. temperature regulator 14. rear lead plate 15. front lead plate 16. fixed lead plate 17. drinking water bottle 18. support side plate 19. radiation monitor 20. lead plate mounting slot 21. light regulator 22. guide rail 23. support frame. DETAILED DESCRIPTION

[0025] Figures 1 to 7 This is the best embodiment of the present invention, Figures 1 to 7 The utility model is further described.

[0026] like Figure 1 As shown, the utility model is a mouse radiation protection IVC system, including a host 1, a cage 2 and a cage 3. The host 1 is arranged on one side of the cage 2, and several cages 3 are installed on the cage 2. A light regulator 21 is provided on the cage 2. In this embodiment, a light regulator 21 is provided on each side of the cage 2. The control system in the host 1 can adjust the light regulator 21 to simulate the growth of experimental animals under light in a natural environment, and can adjust the light cycle, light intensity and color temperature; a radiation detector 19 is installed on one side of each cage 3, and lead plates are provided on the side and bottom of each cage 3. The radiation detector 19 can monitor the radiation conditions of the living environment of the experimental mice in real time, and the lead plates around the cage 3 can effectively protect the experimental animals in the cage 3 from radiation interference.

[0027] An air supply mechanism and an exhaust mechanism are provided between the main unit 1 and the cage frame 2. The air supply mechanism and the exhaust mechanism are respectively connected to each cage box 3. The air supply mechanism provides fresh air for the mice in the cage box 3. At the same time, the exhaust mechanism extracts the exhaust gas in the cage box 3. The main unit 1 is also equipped with a temperature and humidity sensor, a wind speed sensor, a pressure difference sensor, etc., which can monitor the temperature and humidity of the entire system, the size of the wind speed inside the system, and the pressure difference inside the cage box 3 in real time, so that the experimenters can understand the living environment of the experimental mice in real time in the monitoring room, thereby ensuring that the mice can metabolize, reproduce and carry out other life activities normally in a comfortable environment.

[0028] The main unit 1 is provided with a main unit screen 4 and an alarm light 7. The main unit screen 4 is a touch screen. System parameters such as the ventilation rate, pressure differential value, and the maximum and minimum temperature and humidity values are set on the main unit screen 4 for easy operation. The main unit screen 4 can also realize the function of the screen being on during the day and off at night, ensuring that the nocturnal life activities of the experimental small animals are not disturbed by light. The alarm light 7 is used to continuously flash when the main unit 1 experiences malfunctions such as unstable pressure differential, large changes in temperature and humidity, and unstable ventilation rate, so that the operator can easily observe the system abnormality and avoid damage to the normal life activities of the experimental animals caused by the system abnormality. Casters 8 are provided below the main unit 1 and the cage frame 2. Casters 8 are universal casters with self-locking function.

[0029] like Figure 2 As shown, the air supply mechanism includes an air supply pipe 6, an air supply box 9 and an air supply fan 10. The air outlet of the air supply fan 10 is connected to the air supply box 9, and the air inlet of the air supply fan 10 is connected to the outside world. One end of the air supply pipe 6 is connected to the air supply box 9, and the other end of the air supply pipe 6 is connected to each cage box 3. Air is continuously supplied to each cage box 3 through the air supply fan 10. A temperature regulator 13 is installed on the air supply box 9. When the temperature and humidity sensor detects the internal temperature of the system environment, when the internal temperature of the system environment is lower than the set temperature, the temperature regulator 13 turns on the heating mode. When the temperature reaches the set value, the temperature regulator stops heating, thereby effectively ensuring the stability of the internal temperature of the system and providing a constant temperature for the experimental animals. A warm growth environment is provided to ensure that all life activities of the experimental animals are normal; the exhaust mechanism includes an exhaust pipe 5, an exhaust box 11 and an exhaust fan 12. The exhaust branch pipes of each cage 3 are connected to the exhaust box 11, the air inlet of the exhaust fan 12 is connected to the exhaust box 11, the air outlet of the exhaust fan 12 is connected to the exhaust pipe 5, the exhaust pipe 5 is connected to the outside world, and a temperature regulator 13 is installed on the exhaust box 11. The purpose of setting the temperature regulator 13 in the exhaust mechanism is because the exhaust branch pipe is a long distance away from the exhaust box 11. During this process, the temperature will continue to drop, thereby affecting the temperature inside the cage 3. Therefore, a temperature regulator 13 is also set in the exhaust box 11 for heating to ensure that the internal temperature of the system is stable.

[0030] Filters are installed in both the exhaust box 11 and the supply box 9. Both the air entering the cage 3 and the air being exhausted are filtered by the filters. In this embodiment, two supply fans 10 and two exhaust fans 12 are provided. When the system is operating normally, the two supply fans 10 operate simultaneously. When one of the two supply fans 10 is damaged, the host 1 controls the power of the other supply fan 10 to increase to meet the air volume required by the system. When the system is operating normally, the two exhaust fans 12 operate simultaneously. When one of the exhaust fans 12 is damaged, the host 1 controls the power of the other exhaust fan 12 to increase to ensure that the exhaust gas inside the system is discharged normally.

[0031] like Figures 3 and 4 As shown, the lead plate includes a fixed lead plate 16, a front lead plate 14 and a rear lead plate 15. The fixed lead plate 16 is installed under the cage box 3. The fixed lead plate 16 includes an integrally formed bottom plate and two side plates. Lead plate mounting grooves 20 are provided on the front and rear sides of the fixed lead plate 16. The front lead plate 14 and the rear lead plate 15 are respectively installed in the two lead plate mounting grooves 20. The lead plate in this embodiment uses stainless steel sheet metal to encapsulate lead liquid or stainless steel sheet metal to encapsulate lead plate. Using stainless steel sheet metal to encapsulate lead liquid or lead plate can effectively protect the experimenter, because lead has certain toxicity. Long-term contact with exposed lead will be harmful to the health of the experimenter. Secondly, the laboratory needs to use disinfectant for disinfection spray or wiping regularly. Stainless steel sheet metal can effectively protect the internal lead plate to avoid exposure. Lead has a high density, which enables it to effectively absorb and scatter radiation, including X-rays, gamma rays, etc. At the same time, the high atomic number of lead also enhances its ability to block radiation. Lead plates are widely used in hospital X-ray rooms, CT rooms, radiotherapy rooms, etc. to make protective walls, isolation screens, nurse stations, etc. to protect medical staff and patients from radiation harm.

[0032] In this embodiment, the thickness of the lead plate is 8 mm. The 8 mm thickness here refers to the effective thickness of 8 mm after the lead liquid solidifies. This size can effectively protect experimental mice of different ages and can effectively prevent radiation such as X-rays, gamma rays, and neutrons.

[0033] like Figures 5 and 6 As shown, a support frame 23 is provided on the lower side of each fixed lead plate 16. The support frame 23 is fixedly provided on the cage frame 2. The function of the support frame 23 is to support the lead plate. Since the lead plate is very heavy, it is prevented from falling off from the cage frame 2.

[0034] like Figure 7As shown, a plurality of independent spaces for placing cages 3 are arranged on the cage frame 2. Guide rails 22 are provided on both sides of each independent space. Support side panels 18 are provided on both sides of each cage 3. Support side panels 18 are mounted on the guide rails 22, which support the cage 3. Water bottles 17 and 26 are also provided on the cages 3 to provide water for the experimental animals, ensuring their normal life activities.

[0035] When the present invention is in use, each cage box 3 is installed on the cage frame 2, and the host 1 is powered on. It can remotely monitor the experimental mice and detect the temperature and humidity parameters of the entire system, the system air flow velocity, and the pressure difference in the cage box. The air intake mechanism delivers fresh and clean air to the cage box 3, and the exhaust mechanism discharges the exhaust gas in the cage box 3. At the same time, the control system in the host 1 adjusts the light regulator 21 to simulate the growth of experimental animals under light in a natural environment, and can adjust the light cycle, light intensity, and color temperature. When the internal temperature of the system is lower than the set temperature, the temperature regulator 13 is turned on to heat the flowing gas inside the system, effectively ensuring the stability of the internal environmental temperature of the system. Similarly, the host 1 can detect the radiation conditions of the living environment of the mice under the protection of the lead plate, and the lead plate can effectively protect the experimental animals from radiation damage.

[0036] The above description is merely a preferred embodiment of the present invention and does not constitute any limitation thereto. Any person skilled in the art may utilize the above disclosure to modify or remodel the present invention into equivalent embodiments. However, any simple modification, equivalent variation, or modification of the above embodiment that does not depart from the technical content of the present invention and is based on the technical essence of the present invention shall still fall within the scope of protection of the present invention.

Claims

1. A mouse radiation protection IVC system, characterized by: The invention comprises a main unit (1), a cage frame (2) and a cage box (3), wherein the main unit (1) is arranged on one side of the cage frame (2), a plurality of cage boxes (3) are installed on the cage frame (2), a light regulator (21) is arranged on the cage frame (2), a radiation detector (19) is installed on one side of each cage box (3), a lead plate is arranged on the side and bottom of each cage box (3), an air supply mechanism and an air exhaust mechanism are arranged between the main unit (1) and the cage frame (2), and the air supply mechanism and the air exhaust mechanism are respectively connected to each cage box (3).

2. The mouse radiation protection IVC system according to claim 1, characterized in that: The lead plate comprises a fixed lead plate (16), a front lead plate (14) and a rear lead plate (15). The fixed lead plate (16) is installed below the cage box (3). The fixed lead plate (16) comprises an integrally formed bottom plate and two side plates. Lead plate mounting grooves (20) are provided on the front and rear sides of the fixed lead plate (16). The front lead plate (14) and the rear lead plate (15) are respectively installed in the two lead plate mounting grooves (20).

3. The mouse radiation protection IVC system according to claim 2, characterized in that: A support frame (23) is provided on the lower side of each fixed lead plate (16), and the support frame (23) is fixedly provided on the cage frame (2).

4. A mouse radiation protection IVC system according to claim 1 or 2, characterized in that: The thickness of the lead plate is 8 mm.

5. The mouse radiation protection IVC system according to claim 1, characterized in that: A temperature regulator (13) is provided on both the air supply mechanism and the air exhaust mechanism.

6. The mouse radiation protection IVC system according to claim 1, characterized in that: The air supply mechanism includes an air supply pipe (6), an air supply box (9) and an air supply fan (10), the air outlet of the air supply fan (10) is connected to the air supply box (9), one end of the air supply pipe (6) is connected to the air supply box (9), and the other end of the air supply pipe (6) is connected to each cage box (3), and a temperature regulator (13) is installed on the air supply box (9); the exhaust mechanism includes an exhaust pipe (5), an exhaust box (11) and an exhaust fan (12), the exhaust branch pipes of each cage box (3) are connected to the exhaust box (11), the air inlet of the exhaust fan (12) is connected to the exhaust box (11), the air outlet of the exhaust fan (12) is connected to the exhaust pipe (5), and a temperature regulator (13) is installed on the exhaust box (11).

7. The mouse radiation protection IVC system according to claim 6, characterized in that: Filters are provided in both the exhaust box (11) and the supply box (9).

8. The mouse radiation protection IVC system according to claim 1, characterized in that: A plurality of independent spaces for placing cage boxes (3) are arranged on the cage frame (2), guide rails (22) are provided on both sides of each independent space, and support side panels (18) are provided on both sides of each cage box (3), and the support side panels (18) are mounted on the guide rails (22).

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