Biological safety cabinet of multifunctional monitoring system
By setting up microparticle and plankton monitoring channels in the biosafety cabinet, the difficulty of cleaning and airflow impact of traditional biosafety cabinets is solved, and effective monitoring and sample collection of sterile environments are achieved.
Patent Information
- Application Number
- CN202422297256.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-19
- Publication Date
- 2025-08-19
- Estimated Expiration
- 2034-09-19
AI Technical Summary
Traditional biosafety cabinets cannot meet the sterile environmental needs of the biopharmaceutical industry. The surveillance camera is placed in the cabinet to increase the difficulty of cleaning, block wind speed and airflow, affect laminar airflow, and the microparticles and plankton bacteria collectors are large in size, affecting normal operation.
Design a biosafety cabinet with a multi-function monitoring system, with an external camera and a collector, which is connected to the inner liner through a bent pipe, and a microparticle and plankton monitoring channel is set up. The collection channel collects samples outside the cabinet, and the controller transmits and monitors data.
It realizes effective monitoring and sample collection of sterile environments, reduces the impact on the work area, maintains airflow fluidity, and reduces the burden of daily cleaning.
Smart Images
Figure CN223233841U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of biosafety cabinets, in particular to a biosafety cabinet with a multifunctional monitoring system. Background Art
[0002] The intended purpose of traditional biosafety cabinets is to provide a clean environment, protect operating samples from environmental contamination, and protect personnel and the environment from the impact of samples. They are suitable for daily microbial operations in ordinary laboratories.
[0003] However, when handling sterile products in the biopharmaceutical industry, traditional biosafety cabinets are no longer able to meet the demands of maintaining a sterile environment within the monitoring cabinet and ensuring traceability of sample operations. Conventional microparticle and airborne microorganism collectors are large, making them inoperable when placed inside the biosafety cabinet for sampling. The collectors themselves can even cause excessive microbial counts in the work area due to their inherent uncleanliness. Routine video surveillance is required for routine operations, and currently, the placement of surveillance cameras inside the biosafety cabinet not only makes daily cleaning difficult but also blocks downdrafts, impacting the laminar airflow within the cabinet.
[0004] Therefore, in summary, it is necessary to provide a new type of biosafety cabinet with a multifunctional monitoring system to address the deficiencies of the existing technology. Utility Model Content
[0005] The utility model provides a biosafety cabinet with a multifunctional monitoring system, which solves the problem that the existing monitoring camera is placed in the biosafety cabinet, which increases the difficulty of daily cleaning, blocks the wind speed of the downdraft, and affects the laminar airflow in the cabinet.
[0006] In order to achieve the above purpose, the technical solution adopted by the utility model is:
[0007] A biosafety cabinet with a multifunctional monitoring system comprises an outer shell, an inner shell arranged inside the outer shell, a threaded connector welded to the side wall of the inner shell, one end of the threaded connector is connected to a first elbow, the other end of the threaded connector is connected to a second elbow, and the second elbow is connected to a planktonic bacteria collector; a third elbow is inserted into the side wall of the inner shell, one end of the third elbow is connected to a microparticle collector; an operating table is provided at the bottom of the inner shell, a planktonic bacteria monitoring channel and a microparticle monitoring channel are provided on the inner wall of the inner shell, and a glass door is provided on the front wall of the inner shell.
[0008] Furthermore, the other end of the second curved pipe extends out of the outer liner, and one end of the second curved pipe extending out of the outer liner is connected to a floating bacteria collector.
[0009] Furthermore, the connection between the second curved pipe and the outer liner is sealed by sealant.
[0010] Furthermore, the third bend is connected to the adapter, and the adapter is fixed to the side wall of the inner liner by bolts and nuts; one end of the third bend is arranged in the inner liner, and the other end of the third bend extends out of the outer liner; the connection between the third bend and the outer liner is sealed by sealant.
[0011] Furthermore, the lower end of the outer liner is connected to the supporting legs, the front wall of the outer liner is provided with a front panel, and the front panel is provided with a controller.
[0012] Furthermore, a connecting bracket is provided at the lower portion of the side wall of the front panel, and a camera is provided on the connecting bracket.
[0013] Furthermore, a primary screen is provided at the front end of the operating table; and a primary screen is provided at the bottom end of the side wall of the inner container.
[0014] The beneficial effects of the present invention are:
[0015] The utility model is equipped with a microparticle collection channel and a planktonic bacteria collection channel, which can collect samples inside the cabinet outside the cabinet and transmit them to the controller, reducing the impact of the collector on the working area, and can effectively collect samples while achieving normal work.
[0016] The camera of the utility model is externally arranged on the outside of the glass door, and the operation inside the equipment can be clearly and effectively monitored through the glass door without affecting the flow of air flow and without involving daily cleaning and maintenance. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] In order to more clearly illustrate the embodiments of the present invention or the technical solutions of the prior art, a brief introduction will be given below to the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.
[0018] Figure 1 It is the main view of the present utility model.
[0019] Figure 2 It is a side view of the present utility model.
[0020] Figure 3 It is a top view of the utility model.
[0021] Figure 4 This is a schematic diagram of the particle collection device and monitoring device in this application.
[0022] Figure 5 This is a schematic diagram of the planktonic bacteria collection device in the present invention.
[0023] Figure 6 This is a schematic diagram of the primary screen arrangement in the present invention.
[0024] Figure 7 This is a schematic diagram of the primary screen structure in this utility model.
[0025] Description of Figure Numbers:
[0026] 1. Bottom leg; 2. Outer liner; 3. Planktonic bacteria monitoring channel; 31. First bend; 32. Threaded connector; 33. Second bend; 4. Microparticle monitoring channel; 41. Third bend; 42. Adapter; 43. Bolt thread; 44. Sealant; 5. Front panel; 51. Connecting bracket; 52. Camera; 6. Inner liner; 7. Glass door; 8. Operating table; 9. Primary screening screen; 10. Controller; 11. Planktonic bacteria collector; 12. Microparticle collector. DETAILED DESCRIPTION
[0027] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments of the present invention can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.
[0028] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. The following description of at least one exemplary embodiment is actually only illustrative and is in no way intended to limit the present invention and its application or use. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.
[0029] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present invention. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, they indicate the presence of features, steps, operations, devices, components and / or combinations thereof.
[0030] Unless otherwise specifically stated, the relative arrangement of the parts and steps, the numerical expressions and the numerical values described in these embodiments do not limit the scope of the present invention. At the same time, it should be clear that, for ease of description, the sizes of the various parts shown in the drawings are not drawn according to the actual proportional relationship. The techniques, methods and equipment known to ordinary technicians in the relevant fields may not be discussed in detail, but where appropriate, the techniques, methods and equipment should be considered as part of the authorization specification. In all examples shown and discussed here, any specific values should be interpreted as being merely exemplary and not as limitations. Therefore, other examples of the exemplary embodiments may have different values. It should be noted that similar numbers and letters represent similar items in the following figures, and therefore, once an item is defined in one figure, it does not need to be further discussed in subsequent figures.
[0031] In the description of the present invention, it needs to be understood that the directions or positional relationships indicated by directional words such as "front, back, up, down, left, right", "horizontal, vertical, vertical, horizontal" and "top, bottom" are usually based on the directions or positional relationships shown in the accompanying drawings. They are only for the convenience of describing the present invention and simplifying the description. Unless otherwise specified, these directional words do not indicate or imply that the device or element referred to must have a specific direction or be constructed and operated in a specific direction. Therefore, they cannot be understood as limiting the scope of protection of the present invention: the directional words "inside and outside" refer to the inside and outside relative to the outline of each component itself.
[0032] For ease of description, spatially relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used herein to describe the spatial positional relationship of a device or feature to other devices or features as shown in the figures. It should be understood that spatially relative terms are intended to include different orientations of the device in use or operation in addition to the orientation described in the figures. For example, if the device in the drawings is inverted, the device described as "above other devices or structures" or "above other devices or structures" will be positioned as "below other devices or structures" or "below their position devices or structures". Thus, the exemplary term "above" can include both "above" and "below". The device can also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatially relative descriptions used here are interpreted accordingly.
[0033] In addition, it should be noted that the use of words such as "first" and "second" to limit components is only for the convenience of distinguishing the corresponding components. Unless otherwise stated, the above words have no special meaning and therefore cannot be understood as limiting the scope of protection of this utility model.
[0034] The utility model provides a technical solution: a biological safety cabinet with a multifunctional monitoring system, such as Figure 1-7 As shown, it includes an outer liner 2, an inner liner 6 is arranged in the outer liner 2, and a threaded connector 32 is welded on the side wall of the inner liner 6, one end of the threaded connector 32 is connected to the first bend 31, and the other end of the threaded connector 32 is connected to the second bend 33, the other end of the second bend 33 extends out of the outer liner 2, and one end of the second bend 33 extends out of the outer liner 2 to be connected to the planktonic bacteria collector 11; the connection between the second bend 33 and the outer liner 2 is sealed by a sealant 44.
[0035] A third curved pipe 41 is inserted into the side wall of the inner liner 6, and the third curved pipe 41 is connected to the adapter 42, and the adapter 42 is fixed to the side wall of the inner liner 6 by bolts and nuts 43; one end of the third curved pipe 41 is set in the inner liner 6, and one end of the third curved pipe 41 extends out of the outer liner 2 and is connected to the particle collector 12; the connection between the third curved pipe 41 and the outer liner 2 is sealed by a sealant 44.
[0036] An operating table 8 is provided at the bottom of the inner container 6 , a planktonic bacteria monitoring channel 3 and a microparticle monitoring channel 4 are provided on the inner wall of the inner container 6 , and a glass door 7 is provided on the front wall of the inner container 6 .
[0037] The lower end of the outer liner 2 is connected to the bottom leg 1, and the front wall of the outer liner 2 is provided with a front panel 5, and the controller 10 is provided on the front panel 5; the lower part of the side wall of the front panel 5 is provided with a connecting bracket 51, and the connecting bracket 51 is provided with a camera 52, and the transmission line of the camera 52 is connected to the controller 10.
[0038] A primary screen 9 is provided at the front end of the operating table 8 ; a primary screen 9 is provided at the bottom end of the side wall of the inner container 6 .
[0039] Assembly process:
[0040] The third elbow 41 and the adapter 42 are connected together by welding to form an assembly, and then the assembly is connected to the inner liner 6 by bolts and nuts 43. After being assembled with the outer liner 2, the joint is sealed with sealant 44.
[0041] The threaded connector 32 is welded to the inner liner 6 by welding, and the first bend 31 and the second bend 33 are connected through the threaded connector 32 . After being assembled with the outer liner 2 , the connection is sealed with a sealant 44 .
[0042] Assemble the front panel 5, the connecting bracket 51, and the camera 52, and then respectively install and assemble the bottom legs 1, the outer liner 2 and the inner liner 6, the glass door 7, the operating table 8, and the primary screening net 9 to form the final product.
[0043] Usage process:
[0044] When using a safety cabinet, the number of particles in the cabinet is monitored through the particle monitoring channel. The number of particles is an important indicator for cleanliness evaluation, and the cleanliness level of the cabinet can be determined by the number of particles. When the expected environment of the product is Class A, the number of 5μm particles in the cabinet is required to be ≤20 / m3, and the number of 0.5μm particles is required to be ≤3520 / m3. If this standard is exceeded, the environment in the cabinet is determined to be unsuitable for the intended use.
[0045] Implementation method: After the equipment is started, the particle collector 12 begins to collect air and identify the number of particles, and transmits the data to the controller 10 on the product. When the number of particles in the cabinet exceeds the set value, the controller 10 triggers an alarm, prompting the user that there is a problem with the cleanliness of the cabinet, and to stop using it and conduct an investigation.
[0046] Online sampling of planktonic bacteria can be completed through the planktonic bacteria monitoring channel. The number of planktonic bacteria is an important indicator for the evaluation of sterile production. The culture dish is placed on the planktonic bacteria monitoring channel 3, and the air flow in the cabinet passes through the culture dish through the operation of the planktonic bacteria collector 11. After sampling, the culture dish is placed in a biochemical incubator and cultured at 30℃~35℃ for 3~5 days. The results are observed. Sterile production requires that the number of colonies after culture is less than 1CFU / dish to be qualified.
[0047] The camera 52 can be used to monitor in real time the accuracy of particle and airborne bacteria sampling, the loading and unloading of samples in the cabinet, and other information such as sample manipulation. The camera 52 has the advantage of being placed outside the glass door 7, effectively avoiding the camera 52 being located within the work area and affecting the airflow within the work area, and can also reduce the need for daily cleaning of the camera. The signals collected by the camera 52 can be transmitted to the controller 10.
[0048] The above is only a preferred specific implementation method of the present invention, but the protection scope of the present invention is not limited to this. Any technician familiar with the technical field within the technical scope disclosed by the present invention can make equivalent replacements or changes based on the technical solution and inventive concept of the present invention, which should be covered by the protection scope of the present invention.
Claims
1. A biosafety cabinet with a multifunctional monitoring system, characterized in that: The invention comprises an outer liner (2), an inner liner (6) is arranged in the outer liner (2), a threaded connector (32) is welded on the side wall of the inner liner (6), one end of the threaded connector (32) is connected to a first curved pipe (31), the other end of the threaded connector (32) is connected to a second curved pipe (33), and the second curved pipe (33) is connected to a floating bacteria collector (11); a third curved pipe (41) is inserted into the side wall of the inner liner (6), one end of the third curved pipe (41) is connected to a microparticle collector (12); an operating table (8) is arranged at the bottom of the inner liner (6), a floating bacteria monitoring channel (3) and a microparticle monitoring channel (4) are arranged on the inner wall of the inner liner (6), and a glass door (7) is arranged on the front wall of the inner liner (6).
2. The biosafety cabinet with a multifunctional monitoring system according to claim 1, characterized in that: The other end of the second curved pipe (33) extends out of the outer bladder (2), and one end of the second curved pipe (33) extending out of the outer bladder (2) is connected to the floating bacteria collector (11).
3. The biosafety cabinet of the multifunctional monitoring system according to claim 2, characterized in that: The connection between the second curved pipe (33) and the outer bladder (2) is sealed by a sealant (44).
4. The biosafety cabinet with a multifunctional monitoring system according to claim 1, characterized in that: The third curved pipe (41) is connected to the adapter (42), and the adapter (42) is fixed to the side wall of the inner liner (6) by means of bolts and nuts (43); one end of the third curved pipe (41) is arranged in the inner liner (6), and the other end of the third curved pipe (41) extends out of the outer liner (2); the connection between the third curved pipe (41) and the outer liner (2) is sealed by means of a sealant (44).
5. The biosafety cabinet with a multifunctional monitoring system according to claim 1, characterized in that: The lower end of the outer bladder (2) is connected to the bottom leg (1), and the front wall of the outer bladder (2) is provided with a front panel (5), and the front panel (5) is provided with a controller (10).
6. The biosafety cabinet with a multifunctional monitoring system according to claim 5, characterized in that: A connecting bracket (51) is provided at the lower part of the side wall of the front panel (5), and a camera (52) is provided on the connecting bracket (51).
7. The biosafety cabinet with a multifunctional monitoring system according to claim 1, characterized in that: The front end of the operating table (8) is provided with a primary screen (9); the bottom end of the side wall of the inner container (6) is provided with a primary screen (9).