Calibration element and optical detection device
By designing a calibration element with a second surface with uneven concave and uneven convex convexity, the fixed protrusions replace the thermal motion of particles in the emulsion, the interstage difference and noise problems of the optical detection device between different analyzers are solved, and a more accurate calibration effect is achieved.
Patent Information
- Application Number
- CN202421350836.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-13
- Publication Date
- 2025-08-19
- Estimated Expiration
- 2034-06-13
AI Technical Summary
The existing optical detection devices have interstage differences between different analyzers, resulting in large differences in the concentration of the same solution to be tested between the instruments, and the noise and concentration differences in calibration with emulsions lead to an increase in error.
A calibration element is designed with a second uneven surface, and by providing a plurality of first protrusions to scatter light, the fixed protrusion replaces the thermal motion of particles in the emulsion to ensure the stability of the light signal.
Accurate calibration of different analyzers is achieved, errors between instruments are reduced, and the stability and accuracy of calibration are improved.
Smart Images
Figure CN223244327U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medical device calibration tools, in particular to a calibration element and an optical detection device. Background Art
[0002] Currently, in the medical field, when testing some medical solutions, such as protein solutions, optical detection devices are used to emit light to illuminate the solution for detection. Optical detection devices generally include an optical device, a base, and a photoelectric sensor. The light emitted by the optical device passes through a hole in the base, illuminates the solution, and is received by the photoelectric sensor. The solution is tested using nephelometry. In nephelometry, the photoelectric sensor receives light scattered by solution particles at a certain angle to the incident light. Therefore, there is a certain angle between the normal direction of the photoelectric sensor and the propagation direction of light. This angle tolerance must be strictly controlled. Otherwise, the light signal received by the photoelectric sensor will vary, resulting in large errors in testing between different instruments.
[0003] The optical detection devices in different analyzers can experience variations in optical signal intensity, known in the industry as "inter-instrument variability." This variability can lead to significant discrepancies in the concentration of the same test solution measured by different instruments. A common optical signal calibration method involves preparing a standard emulsion with one or more reagents. A high-performance instrument is then used to measure the standard emulsion to obtain an optical signal value. This optical signal value is then used as a reference for calibrating other instruments to ensure that the same optical signal value is obtained when measuring the standard emulsion.
[0004] However, the particles in the emulsion will undergo irregular thermal motion, and when light shines on these particles, signal fluctuations will occur. This signal fluctuation is noise, which means that using emulsion to calibrate the "inter-instrument difference" will still cause certain differences between instruments; secondly, the concentration of the emulsion prepared before each calibration is different, and this difference will further increase the difference between instruments to a certain extent. Utility Model Content
[0005] In view of this, the present invention provides a calibration element and an optical detection device, which are used to solve the technical problem that there are large errors in the existing calibration of different analyzers.
[0006] In order to solve the above technical problems, the first technical solution adopted by the present invention is:
[0007] A calibration element has a first side and a second side opposite to each other, light can enter from the first side and pass through the second side, a first surface is provided on the first side, a second surface is provided on the second side, and a plurality of first protrusions are provided on the second surface to make the second surface uneven, thereby being able to scatter light entering from the first surface and passing through the second surface.
[0008] In some embodiments of the calibration element, a plurality of second protrusions are further provided on the first surface, so that the first surface is uneven.
[0009] In some embodiments of the calibration element, a first groove is formed on the first side, and a bottom surface of the first groove is the first surface.
[0010] In some embodiments of the calibration element, a second groove is formed on the second side, and a bottom surface of the second groove is the second surface.
[0011] In some embodiments of the calibration element, a distance between any two points on the sidewalls of the first protrusion and / or the second protrusion does not exceed 1.2 mm and a maximum value is not less than 1.0 mm.
[0012] In some embodiments of the calibration element, a distance between adjacent second protrusions on the first surface is 0.8 mm-1.0 mm; and / or a distance between adjacent first protrusions on the second surface is 0.8 mm-1.0 mm.
[0013] In some embodiments of the calibration element, the first protrusion and / or the second protrusion is in the shape of a hemisphere or a cylinder.
[0014] In some embodiments of the calibration element, a protrusion is further provided on the calibration element to form a platform, and the body of the calibration element and the platform are combined to form an L-shape or a T-shape, and the platform is used to be clamped on the base.
[0015] In some embodiments of the calibration element, the platform has a table surface opposite to the calibration element body, and an orthographic projection area of the calibration element body toward the table surface is smaller than an area of the table surface.
[0016] In order to solve the above technical problems, the second technical solution adopted by the present invention is:
[0017] An optical detection device, comprising:
[0018] A base having a first hole and a second hole that are discontinuous, and a placement groove that is in communication with both the first hole and the second hole;
[0019] an optical device capable of extending into the first hole and used for transmitting optics;
[0020] a photoelectric sensor, disposed on a side of the second hole away from the first hole and configured to receive light emitted from the second hole;
[0021] And the calibration element described in the previous embodiment, the calibration element can extend into the placement groove, so that the light emitted by the optical device passes through the first side and enters the second hole after being scattered by the second side.
[0022] The implementation of the present invention will have at least the following beneficial effects:
[0023] The above-mentioned calibration element is applied to an optical detection device, which can enable itself and the optical detection device to have the technical effect of small calibration error for different analyzers. Specifically, the calibration element of the present invention can allow light to pass through, and due to the effect of the first protrusion on the second surface of the second side, the light will be scattered when passing through the first protrusion. Compared with the emulsion equipped in the calibration element, the first protrusion is fixed, so the scattered light intensity signal will not change like the thermal motion of particles in the emulsion, thereby enabling more accurate calibration of each analyzer, solving the technical problem of large errors in the existing calibration of different analyzers. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.
[0025] Figure 1 Schematic diagram of the overall structure of an optical detection device in one embodiment;
[0026] Figure 2 is a cross-sectional view of an optical detection device in one embodiment;
[0027] Figure 3 for Figure 1 Schematic diagram of the structure of the calibration element;
[0028] Figure 4 for Figure 3 Schematic diagram of the structure on the other side of the calibration component.
[0029] in:
[0030] 1. Body; 2. Platform; 3. First side; 31. First groove; 32. First surface; 4. Second side; 41. Second groove; 42. Second surface; 43. First protrusion;
[0031] 5. Base; 51. First hole; 52. Second hole; 53. Placement slot; 6. Optical device; 7. Photoelectric sensor. DETAILED DESCRIPTION
[0032] To facilitate understanding of the present invention, a more comprehensive description of the present invention will be provided below with reference to the accompanying drawings. The drawings illustrate preferred embodiments of the present invention. However, the present invention may be implemented in many other forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to provide a more thorough and comprehensive understanding of the disclosure of the present invention.
[0033] It should be noted that when an element is referred to as being "fixed to" another element, it may be directly attached to the other element or there may be an intermediate element. When an element is referred to as being "connected to" another element, it may be directly connected to the other element or there may be an intermediate element. The terms "vertical," "horizontal," "left," "right," and similar expressions used herein are for illustrative purposes only.
[0034] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which this invention pertains. The terms used herein in the specification of this invention are intended only to describe specific embodiments and are not intended to limit the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.
[0035] like Figure 1-4 As shown, in an embodiment of the calibration element, the calibration element has a first side 3 and a second side 4 opposite to each other, and light can enter from the first side 3 and pass through the second side 4. A first surface 32 is provided on the first side 3, and a second surface 42 is provided on the second side 4. A plurality of first protrusions 43 are provided on the second surface 42 to make the second surface 42 uneven, thereby being able to scatter light entering from the first surface 32 and passing through the second surface 42.
[0036] In this embodiment, the calibration element allows light to pass through. Due to the action of the first protrusion 43 on the second surface 42 of the second side 4, the light will be scattered when passing through the first protrusion 43. Compared with the emulsion provided in the calibration element, the first protrusion 43 is fixed, so the scattered light intensity signal will not change due to the thermal motion of particles in the emulsion, thereby enabling more accurate calibration of each analyzer, solving the technical problem of large errors in the existing calibration of different analyzers.
[0037] Specifically, the calibration element can be a block-shaped structure, such as a rectangular block, a square block, or a polygonal prism structure. In terms of arrangement, the first surface 32 can be perpendicular to the incident direction of the light, so that the direction of the light does not change. The light is then scattered by the first protrusions 43 on the second surface 42. To this end, the first surface 32 and the second surface 42 are preferably parallel.
[0038] More specifically, the calibration element can be manufactured by an injection molding process, and the first surface 32 can be a surface with a relatively high smoothness.
[0039] In an embodiment of the calibration element, a plurality of second protrusions are further provided on the first surface 32 to make the first surface 32 uneven.
[0040] In combination with the previous embodiment, in this embodiment, protrusions are provided on both the first surface 32 and the second surface 42 to ensure scattering, thereby improving the stability of the calibration test.
[0041] In an embodiment of the calibration element, a first groove 31 is defined on the first side 3 , and a bottom surface of the first groove 31 is a first surface 32 .
[0042] In this embodiment, the first groove 31 is provided, and a sunken design is formed compared to the notch position of the first groove 31 , thereby preventing the first surface 32 and the second protrusion on the first surface 32 from being scratched.
[0043] In an embodiment of the calibration element, a second groove 41 is formed on the second side 4 , and a bottom surface of the second groove 41 is a second surface 42 .
[0044] In combination with the previous embodiment, similarly, by providing the second groove 41 , a sunken design is formed at the position of the notch of the second groove 41 , thereby preventing the second surface 42 and the first protrusion 43 on the second surface 42 from being scratched.
[0045] It should also be noted that both the first protrusion 43 and the second protrusion are microstructures. This arrangement facilitates compact arrangement, such as uniform distribution, to ensure that light passes through the protrusions. Specifically, in one embodiment of the calibration element, the distance between any two points on the sidewalls of the first protrusion 43 and / or the second protrusion does not exceed 1.2 mm, and the maximum distance is no less than 1.0 mm.
[0046] In this embodiment, taking the first and second protrusions 43 and 44 as arched shapes, the edges and surfaces of the protrusions are circular, elliptical, or other shapes, with a size range of 1.0 mm to 1.2 mm. This small size facilitates compact arrangement and prevents scratches caused by protrusions. Furthermore, compared to larger protrusions, the further distance from the second hole 51 on the base 5 facilitates light scattering into the second hole 51. The shapes of the first and second protrusions 43 and 44 can be various, such as an arched bridge structure, a column, a cone, or a portion of a sphere.
[0047] In one embodiment of the calibration element, the distance between adjacent second protrusions on the first surface 32 is 0.8 mm to 1.0 mm, and / or the distance between adjacent first protrusions 43 on the second surface 42 is 0.8 mm to 1.0 mm.
[0048] In this embodiment, the second protrusions can be arranged in a matrix or other manner to be evenly distributed, and the spacing between adjacent protrusions is small, which is conducive to forming a tight arrangement, thereby ensuring that light can be scattered after passing through. The first protrusions 43 are similar and will not be described in detail.
[0049] In one embodiment of the calibration element, the first protrusion 43 and / or the second protrusion are in the shape of a hemisphere or a cylinder.
[0050] In this embodiment, by configuring the first protrusion 43 to be a hemisphere or a cylinder, processing can be facilitated and consistency can be improved. The second protrusion is similarly described and will not be further described.
[0051] In an embodiment of the calibration element, a protrusion is further provided on the calibration element to form a platform 2 . The body 1 of the calibration element and the platform 2 are combined to form an L-shape or a T-shape. The platform 2 is used to be clamped on the base 5 .
[0052] In this embodiment, it can be understood that the calibration element is divided into two parts, one part is a main body 1 having a first side 3 and a second side 4, and the other part is a platform 2 formed by a protrusion. The two are integrally formed, and the platform 2 is formed at the end of the main body 1, so that an L-shaped or T-shaped structural shape can be formed, which can be conveniently connected with the base 5, for example, placed on the base 5. In this way, when the platform 2 is placed at the same position on different bases 5 each time, variables can be eliminated to ensure that the position of the calibration element relative to the base 5 is in one place, thereby improving the accuracy of calibration.
[0053] In an embodiment of the calibration element, the platform 2 has a table surface opposite to the calibration element body 1 , and the orthographic projection area of the calibration element body 1 toward the table surface is smaller than the area of the table surface.
[0054] In this embodiment, specifically, the plane size of the platform 2 is larger than the main body 1, so that when the platform 2 is placed on the base 5, the main body 1 can be prevented from colliding with the base 5. The large size of the platform 2 can also make it easier for staff to pick it up, avoiding direct contact between human hands or robotic arms and the protrusions, thereby avoiding scratching the protrusions.
[0055] The present invention also relates to an optical detection device, comprising the calibration element of the previous embodiment, as well as a base 5, an optical device 6, and a photoelectric sensor 7. The base 5 is provided with a first hole 51 and a second hole 52, which are non-contiguous, and a placement slot 53 communicating with both the first hole 51 and the second hole 52. The optical device 6 is capable of extending into the first hole 51 and is configured to emit light. The photoelectric sensor 7 is disposed on a side of the second hole 52, away from the first hole 51, and is configured to receive light emitted from the second hole 52.
[0056] In combination with the previous embodiment, the platform 2 is placed on the slot of the placement slot 53, the extension direction of the first hole 51 is perpendicular to the first surface 32, and the optical device 6 emits light to the calibration element placed in the placement slot 53. The optical light enters the calibration element from the first surface 32 and is emitted from the second surface 42. After being scattered by the second protrusion on the second surface 42, it can enter the second hole 52 and be received by the photoelectric sensor 7. The photoelectric sensor 7 receives the signal to obtain a standard optical signal value, and then the calibration element is placed in each optical detection device in each analyzer for calibration.
[0057] It should be noted that the optical detection device in this embodiment can be used as a standard calibration tool, that is, the optical detection device is independent, and can also be used to measure standard optical signal values.
[0058] The technical features of the above embodiments can be combined arbitrarily. In order to make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0059] The above embodiments merely illustrate several implementations of the present invention. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that a person skilled in the art would be able to make numerous variations and improvements without departing from the spirit of the present invention, and these variations and improvements fall within the scope of protection of the present invention. Therefore, the scope of protection of the present utility model patent shall be determined by the appended claims.
Claims
1. A calibration element, characterized in that The calibration element has a first side and a second side opposite to each other, and light can enter from the first side and exit from the second side. A first surface is provided on the first side, and a second surface is provided on the second side. A plurality of first protrusions are provided on the second surface to make the second surface uneven, thereby scattering the light entering from the first surface and exiting from the second surface.
2. The calibration element according to claim 1, wherein A plurality of second protrusions are further provided on the first surface to make the first surface uneven.
3. The calibration element according to claim 1, wherein A first groove is formed on the first side, and a bottom surface of the first groove is the first surface.
4. The calibration element according to claim 1, wherein A second groove is formed on the second side, and a bottom surface of the second groove serves as the second surface.
5. The calibration element according to claim 2, wherein The distance between any two points on the sidewall of the first protrusion and / or the second protrusion does not exceed 1.2 mm and the maximum value is not less than 1.0 mm.
6. The calibration element according to claim 2, wherein The spacing between adjacent second protrusions on the first surface is 0.8 mm-1.0 mm; and / or the spacing between adjacent first protrusions on the second surface is 0.8 mm-1.0 mm.
7. The calibration element according to claim 2, wherein The first protrusion and / or the second protrusion are in a shape of a hemisphere or a cylinder.
8. The calibration element according to claim 1, wherein The calibration element is further provided with a protrusion to form a platform. The body of the calibration element is combined with the platform to form an L-shape or a T-shape. The platform is used to be clamped on the base.
9. The calibration element according to claim 8, wherein The platform has a table surface opposite to the calibration element body, and an orthographic projection area of the calibration element body toward the table surface is smaller than an area of the table surface.
10. An optical detection device, characterized in that: include: A base having a first hole and a second hole that are discontinuous, and a placement groove that is in communication with both the first hole and the second hole; an optical device capable of extending into the first hole and used for transmitting optics; a photoelectric sensor, disposed on a side of the second hole away from the first hole and configured to receive light emitted from the second hole; And the calibration element according to any one of claims 1 to 9, wherein the calibration element can extend into the placement groove so that light emitted by the optical device passes through the first side and enters the second hole after being scattered by the second side.