Full-automatic transdermal diffusion system

Abstract

The utility model discloses a full-automatic transdermal diffusion system which comprises an experiment shell, the experiment shell comprises an automatic sampling device, a storage pool, a fixing frame, a transdermal diffusion device and a reaction device, and the automatic sampling device is installed at the rear end in the experiment shell; the storage pool, the fixing frame, the transdermal diffusion device and the reaction device are all mounted in the experiment shell; the automatic sampling device comprises a sliding rail, a driving threaded rod, a control mounting box and a rotary connecting pipe, the driving threaded rod is mounted at the top of the sliding rail, the control mounting box is mounted on the sliding rail, a lifting block is mounted at the bottom of the control mounting box, and the rotary connecting pipe is mounted on the lifting block. According to the device, automatic sampling can be realized, an experimenter does not need to detect a sample regularly, and meanwhile, the experimenter is effectively prevented from staying beside the diffusion cell day and night.

Description

Technical Field

[0001] The utility model relates to the technical field of cosmetic ointment penetration performance testing, in particular to a full-automatic transdermal diffusion system. Background Art

[0002] A transdermal diffusion meter is a tool used to test and evaluate the permeability of drugs, cosmetics, and other substances through human skin. Transdermal diffusion refers to the process by which substances enter the body through human skin. A transdermal diffusion meter can simulate the physiological conditions of human skin and measure and evaluate the permeation rate and amount of drugs, cosmetics, and other substances as they pass through human skin. Transdermal diffusion meters have a wide range of applications in clinical medicine, cosmetics, and other fields. In clinical medicine, transdermal diffusion meters can be used to evaluate the permeability of drugs and their absorption within patients, thereby assessing their efficacy and safety. In the cosmetics field, transdermal diffusion meters can be used to assess the permeability and bioavailability of cosmetic ingredients through human skin, thereby formulating cosmetics suitable for human skin.

[0003] Existing transdermal diffusion instruments have the following defects:

[0004] Existing transdermal diffusion instruments are relatively simple and have a single function. They typically require applying samples such as drugs or cosmetics to transdermal cells and then manually separating them for testing. This method requires manual sampling by experimenters and requires them to stay by the diffusion cell day and night without rest. Therefore, a solution is needed. Utility Model Content

[0005] (1) Technical problems solved

[0006] In view of the deficiencies of the prior art, the present invention provides a fully automatic transdermal diffusion system to solve the problems raised in the above background technology.

[0007] (2) Technical solution

[0008] To achieve the above objectives, the present invention is implemented through the following technical solutions: a fully automatic transdermal diffusion system, including an experimental shell, the experimental shell including an automatic sampling device, a storage tank, a fixing frame, a transdermal diffusion device and a reaction device, the automatic sampling device is installed at the rear end inside the experimental shell, the storage tank, the fixing frame, the transdermal diffusion device and the reaction device are all installed inside the experimental shell, and the transdermal diffusion device is provided in a group, and a group of transdermal diffusion devices is respectively located at the left and right ends of the reaction device; the automatic sampling device includes a sliding rail, a driving threaded rod, a control installation box and a rotating connecting pipe, the driving threaded rod is installed at the top of the sliding rail, the control installation box is installed on the sliding rail, and the rear end is connected to the driving threaded rod, the bottom of the control installation box is installed with a lifting block, the rotating connecting pipe is installed on the lifting block, the top of the rotating connecting pipe is provided with several groups of pump bodies distributed in a laterally equidistant manner, and the bottom input end of the pump body is installed with a sampling needle, and the sampling needle is located at the bottom of the rotating connecting pipe.

[0009] Preferably, the transdermal diffusion device includes a heating block and a diffusion cell. Three groups of installation grooves distributed in a laterally equidistant manner are provided on the top of the heating block. Connecting grooves are provided on the left and right sides of the installation grooves. The diffusion cell is installed in the installation grooves. Fixed feet are provided at the bottom of the heating block.

[0010] Preferably, the diffusion pool is in a cylindrical structure, and sampling tubes are provided on both the left and right sides of the diffusion pool, and the sampling tubes are in an inclined structure.

[0011] Preferably, the reaction device includes a first fixed plate, a second fixed plate and a reaction bottle, the top of the first fixed plate is provided with two groups of connecting columns distributed in a symmetrical manner, the second fixed plate is fixed on the top of the two groups of connecting columns, and the surfaces of the first fixed plate and the second fixed plate are both provided with several groups of fixing holes.

[0012] (3) Beneficial effects

[0013] The utility model provides a fully automatic transdermal diffusion system with the following beneficial effects:

[0014] This fully automatic transdermal diffusion system can realize automatic sampling, eliminating the need for experimenters to test samples regularly. It also effectively avoids experimenters waiting by the diffusion pool day and night without rest, thereby improving the use effect of the device and bringing better convenience to experimenters. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0016] Figure 2 This is a schematic structural diagram of the automatic sampling device of the utility model;

[0017] Figure 3 This is a schematic structural diagram of the side surface of the automatic sampling device of the utility model;

[0018] Figure 4 This is a schematic structural diagram of the transdermal diffusion device of the present invention;

[0019] Figure 5 It is a structural diagram of point A of the present utility model.

[0020] In the figure, 1. Experimental housing; 2. Automatic sampling device; 3. Storage tank; 4. Fixed frame; 5. Transdermal diffusion device; 6. Reaction device; 7. Sliding track; 8. Driving threaded rod; 9. Control installation box; 10. Rotating connecting tube; 11. Lifting block; 12. Pump body; 13. Sampling needle; 14. Heating block; 15. Diffusion tank; 16. Sampling tube; 17. Mounting slot; 18. Connecting slot; 19. Fixing foot; 20. First fixing plate; 21. Second fixing plate; 22. Reaction bottle; 23. Connecting column; 24. Fixing hole. DETAILED DESCRIPTION

[0021] The following will be combined with the accompanying drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0022] See also Figure 1-5 , the embodiment of the utility model provides a technical solution: a fully automatic transdermal diffusion system, including an experimental housing 1, the experimental housing 1 includes an automatic sampling device 2, a storage tank 3, a fixing frame 4, a transdermal diffusion device 5 and a reaction device 6, the automatic sampling device 2 is installed at the rear end of the experimental housing 1, the storage tank 3, the fixing frame 4, the transdermal diffusion device 5 and the reaction device 6 are all installed inside the experimental housing 1, and the transdermal diffusion device 5 is provided in a group, and a group of the transdermal diffusion devices 5 is respectively located at the left and right ends of the reaction device 6;

[0023] The automatic sampling device 2 includes a sliding track 7, a driving threaded rod 8, a control installation box 9 and a rotating connecting tube 10. The driving threaded rod 8 is installed on the top of the sliding track 7. The control installation box 9 is installed on the sliding track 7, and the rear end is connected to the driving threaded rod 8. A lifting block 11 is installed at the bottom of the control installation box 9. The rotating connecting tube 10 is installed on the lifting block 11. The top of the rotating connecting tube 10 is provided with several groups of pump bodies 12 distributed in a laterally equidistant manner. A sampling needle 13 is installed at the bottom input end of the pump body 12. The sampling needle 13 is located at the bottom of the rotating connecting tube 10. When sampling the transdermal diffusion device 5 at different positions, the driving threaded rod 8 can be driven to rotate forward or flip, and further drive the hole control installation box 9 to move left or right on the sliding track 7, and then the rotating connecting tube 10 can be located directly above the transdermal diffusion device 5, and then the lifting block 11 drives the rotating connecting tube 10 to descend, so that the sampling needle 13 on the rotating connecting tube 10 is inserted into the diffusion pool 15, and then the pump body 12 extracts the sample in the diffusion pool 15, and the rotating connecting tube 10 can rotate, and then the sampling tube 16 on the side of the diffusion pool 15 can be inserted for sampling.

[0024] Furthermore, the transdermal diffusion device 5 includes a heating block 14 and a diffusion pool 15. Three groups of mounting grooves 17 are provided on the top of the heating block 14 and are distributed in a laterally equidistant manner. Connecting grooves 18 are provided on the left and right sides of the mounting grooves 17. The diffusion pool 15 is installed in the mounting grooves 17. A fixing foot 19 is provided at the bottom of the heating block 14. The heating block 14 can heat the diffusion pool 15 and can also fix the diffusion pool 15, making it convenient to fix the diffusion pool 15.

[0025] Differently, the diffusion pool 15 is cylindrical in structure, and sampling tubes 16 are provided on both sides of the diffusion pool 15 . The sampling tubes 16 are inclined in structure, and the sampling tubes 16 on the sides of the diffusion pool 15 are for facilitating sampling by the sampling needle 13 .

[0026] Effectively, the reaction device 6 includes a first fixed plate 20, a second fixed plate 21 and a reaction bottle 22. Two groups of connecting columns 23 distributed in a symmetrical manner are provided on the top of the first fixed plate 20. The second fixed plate 21 is fixed on the top of the two groups of connecting columns 23. Several groups of fixing holes 24 are provided on the surfaces of the first fixed plate 20 and the second fixed plate 21. When in use, the sampling needle 13 will inject the sampled material into the reaction bottle 22 in the reaction device 6, which further facilitates the detection of the material.

[0027] Working principle: During operation, when sampling the transdermal diffusion device 5 at different positions, the driving threaded rod 8 can be driven to rotate forward or flip, and further drive the hole control mounting box 9 to move left or right on the sliding track 7, and then the rotating connecting tube 10 can be located directly above the transdermal diffusion device 5, and then the lifting block 11 drives the rotating connecting tube 10 to descend, so that the sampling needle 13 on the rotating connecting tube 10 is inserted into the diffusion pool 15, and then the pump body 12 extracts the sample in the diffusion pool 15, and the rotating connecting tube 10 can rotate, and then the sampling tube 16 on the side of the diffusion pool 15 can be inserted for sampling. After the sampling is completed, the automatic sampling device 2 moves to the top of the reaction device 6, and then the sampling needle 13 will inject the sampled material into the reaction bottle 22 in the reaction device 6, which further facilitates the detection of the material.

[0028] The components of the present invention, 1. experimental housing; 2. automatic sampling device; 3. storage tank; 4. fixing frame; 5. transdermal diffusion device; 6. reaction device; 7. sliding track; 8. driving threaded rod; 9. control installation box; 10. rotating connecting pipe; 11. lifting block; 12. pump body; 13. sampling needle; 14. heating block; 15. diffusion cell; 16. sampling tube; 17. mounting slot; 18. connecting slot; 19. fixing foot; 20. first fixing plate; 21. second fixing plate; 22. reaction bottle; 23. connecting column; 24. fixing hole, are all universal standard parts or parts known to those skilled in the art, and their structure is simple and convenient. The structure and principle are known to technicians in this field through technical manuals or conventional experimental methods. The problem solved by the utility model is that the existing transdermal diffusion instrument is relatively simple and has a single function. It is usually necessary to apply samples such as medicines or cosmetics on the transdermal cells, and then manually let the transdermal diffusion instrument perform separate tests. In this way, the experimenter needs to manually take samples, and the experimenter has to wait by the diffusion pool day and night without any rest. The utility model can realize automatic sampling through the combination of the above-mentioned components, without the experimenter having to test the samples regularly, and at the same time effectively avoids the experimenter having to wait by the diffusion pool day and night.

[0029] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It is obvious to those skilled in the art that the present invention is not limited to the details of the above exemplary embodiments and that the present invention can be implemented in other specific forms without departing from the spirit or essential characteristics of the present invention. Therefore, from all perspectives, the embodiments should be regarded as illustrative and non-restrictive. The scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes that fall within the meaning and range of equivalents of the claims be included in the present invention. Any reference signs in the claims should not be construed as limiting the claim to which they relate.

[0030] In addition, it should be understood that although this specification is described in terms of implementation methods, not every implementation method contains only one independent technical solution. This narrative method of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment can also be appropriately combined to form other implementation methods that can be understood by those skilled in the art.

Claims

1. A fully automatic transdermal diffusion system, characterized by: The invention comprises an experimental housing (1), wherein the experimental housing (1) comprises an automatic sampling device (2), a storage tank (3), a fixing frame (4), a transdermal diffusion device (5) and a reaction device (6), wherein the automatic sampling device (2) is installed at the rear end of the interior of the experimental housing (1), and the storage tank (3), the fixing frame (4), the transdermal diffusion device (5) and the reaction device (6) are all installed inside the experimental housing (1), and the transdermal diffusion device (5) is provided in a group, and the group of transdermal diffusion devices (5) is respectively located at the left and right ends of the reaction device (6); The automatic sampling device (2) comprises a sliding track (7), a driving threaded rod (8), a control installation box (9) and a rotating connecting pipe (10), wherein the driving threaded rod (8) is installed on the top of the sliding track (7), the control installation box (9) is installed on the sliding track (7), and the rear end is connected to the driving threaded rod (8), a lifting block (11) is installed at the bottom of the control installation box (9), and the rotating connecting pipe (10) is installed on the lifting block (11), and a plurality of groups of pump bodies (12) distributed in a transversely equidistant manner are provided on the top of the rotating connecting pipe (10), and a sampling needle (13) is installed at the bottom input end of the pump body (12), and the sampling needle (13) is located at the bottom of the rotating connecting pipe (10).

2. The fully automatic transdermal diffusion system according to claim 1, characterized in that: The transdermal diffusion device (5) comprises a heating block (14) and a diffusion cell (15). The top of the heating block (14) is provided with three groups of mounting grooves (17) distributed in a transversely equidistant manner. Connecting grooves (18) are provided on both the left and right sides of the mounting grooves (17). The diffusion cell (15) is installed in the mounting grooves (17). The bottom of the heating block (14) is provided with fixing feet (19).

3. The fully automatic transdermal diffusion system according to claim 2, characterized in that: The diffusion pool (15) is in a cylindrical structure. Sampling tubes (16) are provided on both the left and right sides of the diffusion pool (15). The sampling tubes (16) are in an inclined structure.

4. The fully automatic transdermal diffusion system according to claim 1, characterized in that: The reaction device (6) comprises a first fixing plate (20), a second fixing plate (21) and a reaction bottle (22); the top of the first fixing plate (20) is provided with two groups of connecting columns (23) distributed in a symmetrical manner; the second fixing plate (21) is fixed on the top of the two groups of connecting columns (23); and the surfaces of the first fixing plate (20) and the second fixing plate (21) are both provided with a plurality of fixing holes (24).

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