Pulse ablation device

Abstract

According to the pulse ablation device, a multi-cavity tube is arranged in a catheter, a first line cavity, a second line cavity and a third line cavity are formed in the multi-cavity tube, a spring tube is arranged in the catheter and arranged on the peripheral face of the outer side of the multi-cavity tube in a sleeving mode, a fixing base is arranged at the far end of the catheter, and the near end of the fixing base is fixed to the far end of the multi-cavity tube; the electrode tip is arranged on the side, back on to the multi-cavity tube, of the fixing base and used for being fixed to target tissue. The electrode assembly comprises a first electrode and a second electrode; the first wire is arranged in the first wire cavity and electrically connected with the first electrode, the second wire is arranged in the second wire cavity and electrically connected with the second electrode, the third wire is arranged in the third wire cavity and electrically connected with the electrode tip, and the first electrode and the second electrode are located between the fixing base and the far end of the spring tube. The far end of the bourdon tube and any one of the first electrode and the second electrode are arranged at intervals in the axial direction of the catheter, and any two of the electrode tip, the first electrode and the second electrode can discharge at the same time and are opposite in electrical property.

Description

Technical Field

[0001] The utility model relates to the technical field of medical equipment, in particular to a pulse ablation device. Background Art

[0002] Atrial fibrillation (atrial arrhythmia) is the most common heart rhythm disorder, characterized by irregular heartbeats. It affects 0.5% to 1.5% of the general population. Patients with atrial fibrillation have a very high risk of stroke, and strokes caused by atrial fibrillation are often more severe, have a higher mortality rate, and are more likely to recur. Therefore, treatment of atrial fibrillation is urgent.

[0003] Pulse ablation is a novel non-thermal ablation technique used to treat atrial fibrillation. This technique uses a high-voltage pulsed electric field to create temporary electroporation holes in the cell membrane, inducing apoptosis and thereby achieving ablation of the target tissue. Pulse ablation offers advantages such as high precision, minimal damage, and rapid recovery, and has been widely used in cardiac therapy and minimally invasive surgery. The pulse ablation catheter is a key device for pulse ablation, delivering the pulsed electric field to the target tissue through the catheter, achieving ablation.

[0004] However, when a traditional pulse ablation catheter enters the body and contacts the target tissue, the electrode arrangement at the distal end of the catheter is restricted within the limited contact area, resulting in insufficient ablation area and affecting the ablation effect.

[0005] The above information disclosed in the background of this application is only used to understand the background of the concept of this application, and does not indicate or suggest that it contains information of the prior art. Utility Model Content

[0006] Based on this, it is necessary to provide a pulse ablation device to address the above problems.

[0007] The present application provides a pulse ablation device, comprising:

[0008] catheter;

[0009] a multi-lumen tube, disposed in the catheter, wherein a first line lumen, a second line lumen, and a third line lumen are formed in the multi-lumen tube;

[0010] A spring tube is provided in the catheter and sleeved on the outer circumference of the multi-lumen tube;

[0011] A fixing seat is provided at the distal end of the catheter, wherein the proximal end of the fixing seat is fixed to the distal end of the multi-lumen tube;

[0012] an electrode head, disposed on a side of the fixing seat facing away from the multi-lumen tube and used for fixing to a target tissue;

[0013] an electrode assembly, comprising a first electrode and a second electrode spaced apart from each other, wherein the first electrode and the second electrode are both disposed on an outer circumferential surface of the distal end of the catheter;

[0014] a first guide wire disposed in the first wire lumen and having a distal end electrically connected to the first electrode;

[0015] a second guide wire disposed in the second wire lumen and having a distal end electrically connected to the second electrode;

[0016] a third wire disposed in the third wire cavity and having a distal end electrically connected to the electrode head;

[0017] The first electrode and the second electrode are located between the fixing seat and the distal end of the spring tube, and the distal end of the spring tube is spaced apart from either the first electrode or the second electrode in the axial direction of the catheter. Any two of the electrode head, the first electrode and the second electrode can discharge simultaneously and have opposite electrical properties.

[0018] Before describing the beneficial effects that can be achieved by the pulse ablation device of the present application, it should be noted that, according to many current literatures and animal and human experiments, the ablation effect of pulse ablation depends on the combined effect of multiple factors, among which the electric field size is affected by the electrode size and spacing. The closer to the electrode, the stronger the electric field effect, and the electric field strength gradually decays with increasing distance from the electrode. The smaller the electrode size, the faster the field strength decays with increasing distance, and the tissue ablation effect also decreases accordingly.

[0019] Against this background, the pulse ablation device of the present application can at least achieve the following beneficial effects: the present application optimizes the electrode arrangement, the spacing between the electrode head and the multiple electrodes on the outer circumference of the distal end of the catheter, and any two of the electrode head, the first electrode, and the second electrode can discharge simultaneously and have opposite electrical properties, which can form an effective electric field over a larger range, thereby achieving more uniform tissue ablation and avoiding the problem of insufficient local ablation. This also means that the ablation process is more efficient, thereby reducing surgical time and patient pain, and helping to improve overall treatment efficiency. The independent wire cavity design within the multi-lumen tube makes the wire arrangement more orderly and compact, reducing the possibility of wire entanglement or knotting during surgery, and also ensures electrical isolation between the wires, avoiding signal interference and short circuit problems, and improving the safety and reliability of the device. The structural design of adding a fixing seat and arranging the electrode head on the side of the fixing seat facing away from the multi-lumen tube enables the electrode head to be firmly mounted on the distal end of the catheter, ensuring that the electrode head will not loosen or shift during operation, improving the structural stability of the entire device, and reducing errors caused by catheter movement during surgery. In addition, the distal end of the multi-lumen tube is also connected to the fixing seat, which can also improve the stability of the relative position of the multi-lumen tube in the catheter, ensuring that electrical energy can be efficiently and reliably transmitted to the electrode head for pulse ablation. Among them, the spring tube can provide additional structural support, improve the structural stability of the catheter and the multi-lumen tube, and reduce the shaking or displacement that may occur during operation. The elastic properties of the spring tube give the catheter a certain degree of flexibility during operation, which can better adapt to the complex anatomical structure in the human body and improve the flexibility and accuracy of operation. Because the spring tube has a certain degree of elasticity, it can increase the transmission of torque to the distal end of the catheter during proximal manipulation, improve the maneuverability of the catheter, and facilitate the screwing of the electrode head into the target tissue. In addition, the spring tube is mostly made of metal, so the design of the distal end of the spring tube being spaced apart from the first electrode and the second electrode, that is, the distal end of the spring tube is away from the electrodes, ensuring that the electrodes will not be interfered with by the spring tube during operation, and avoiding the situation where the distal end of the spring tube and the electrode are connected due to high voltage.

[0020] In one embodiment, the fixing seat includes a main body and a protrusion connected to the main body, the protrusion is provided at the distal end of the main body, the electrode head is fixedly sleeved on the outer circumference of the protrusion, and a receiving cavity is provided at the proximal end of the main body, and the receiving cavity is used to be fixed and communicated with the distal end of the multi-lumen tube. The protrusion design of the fixing seat provides a stable structure so that the electrode head can be firmly fixed. The proximal end of the main body is provided with a receiving cavity, and the receiving cavity design of the fixing seat makes it easier to connect with the multi-lumen tube and facilitates installation.

[0021] In one embodiment, the third wire is passed through the fixing base and electrically connected to the electrode head, ensuring that electrical energy can be efficiently and reliably transmitted to the electrode head for pulse ablation.

[0022] In one embodiment, the electrode head is spiral-shaped and can be rotated by the catheter to drill into and fix to the target tissue. The spiral electrode head can rotate under the drive of the catheter to drill into the target tissue, thereby achieving firm fixation. This design not only ensures that the electrode head will not shift easily during the ablation process, but also provides a better fixation effect in irregular or harder tissues. And because the electrode head can penetrate deep into the target tissue, the ablation effect is enhanced. The spiral design increases the contact area between the electrode head and the tissue, allowing electrical energy to be more evenly transmitted to the target area, thereby improving the efficiency and effect of ablation.

[0023] In one embodiment, the distal end of the multi-lumen tube is exposed from the spring tube to be connected to the fixing seat.

[0024] In one embodiment, the first electrode and the second electrode are both annular and are disposed on the outer circumference of the distal end of the catheter, with the first electrode and the second electrode spaced apart in the axial direction of the catheter. The annular electrode covers the outer circumference of the catheter, providing a larger contact area, which helps improve the efficiency of electrical energy conduction and thus improves the ablation efficiency. The design of the annular electrode also makes the electric field distribution more uniform, which helps improve the ablation effect, ensures that the target tissue is subjected to a uniform electric field, and reduces the occurrence of unablated areas.

[0025] In one embodiment, the thickness of the first electrode in the radial direction of the catheter is 0.05 mm-0.3 mm.

[0026] In one embodiment, the width of the first electrode in the axial direction of the catheter is 0.75 mm-4.5 mm.

[0027] In one embodiment, the thickness of the second electrode in the radial direction of the catheter is 0.05 mm-0.3 mm.

[0028] In one embodiment, the width of the second electrode in the axial direction of the catheter is 0.75 mm-4.5 mm.

[0029] In one embodiment, the first and second electrodes are both tile-shaped and spaced apart along the circumference of the catheter on the outer circumference of the catheter. The tile-shaped first and second electrodes are spaced apart along the circumference of the catheter, providing a larger contact area and ensuring uniform distribution of the electric field in the target area, thereby improving electrical energy conduction efficiency and enhancing ablation efficiency and effectiveness.

[0030] In one embodiment, the first electrode and the second electrode are positioned in correspondence with each other in the axial direction of the catheter. Since the first electrode and the second electrode are positioned in correspondence with each other in the axial direction, more precise electric field positioning can be achieved, making the electric field between the two electrodes stronger and more concentrated, enabling more efficient conduction of electrical energy and improving ablation efficiency.

[0031] In one embodiment, the first electrode and the second electrode are at least partially offset in position along the axial direction of the catheter. Since the first electrode and the second electrode are at least partially offset in position along the axial direction of the catheter, the range of action of the electric field is expanded, covering a larger target area and improving the ablation effect.

[0032] In one embodiment, the angle of the first electrode in the circumferential direction of the catheter is 45° to 160°.

[0033] In one embodiment, the thickness of the first electrode in the radial direction of the catheter is 0.05 mm-0.3 mm.

[0034] In one embodiment, the width of the first electrode in the axial direction of the catheter is 1.5 mm to 12 mm.

[0035] In one embodiment, the angle of the second electrode in the circumferential direction of the catheter is 45° to 160°.

[0036] In one embodiment, the thickness of the second electrode in the radial direction of the catheter is 0.05 mm-0.3 mm.

[0037] In one embodiment, the width of the second electrode in the axial direction of the catheter is 1.5 mm to 12 mm.

[0038] In one embodiment, the first and second electrodes are both helical and interlaced around the outer circumference of the distal end of the catheter. This structural design ensures a more uniform distribution of the electric field within the target tissue, helping to improve the uniformity and thoroughness of ablation. The effective ablation range is maintained even at low voltages, as the helical structure consistently ablates surrounding tissue, and the ablation range increases with increasing voltage.

[0039] In one embodiment, both the first electrode and the second electrode are flexible electrodes. BRIEF DESCRIPTION OF THE DRAWINGS

[0040] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the conventional technology, the following briefly introduces the drawings required for use in the embodiments or the conventional technology descriptions. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0041] Figure 1 A schematic structural diagram of a pulse ablation device provided in one embodiment of the present invention.

[0042] Figure 2 A partial cross-sectional view of a pulse ablation device provided in one embodiment of the present invention.

[0043] Figure 3 A partial schematic diagram of a pulse ablation device provided in one embodiment of the present invention without showing a catheter.

[0044] Figure 4 A partial schematic diagram of a pulse ablation device provided by one embodiment of the present invention.

[0045] Figure 5 For this utility model Figure 4 A cross-sectional view of the pulse ablation device at line AA.

[0046] Figure 6 A structural schematic diagram of a fixing base provided in one embodiment of the utility model.

[0047] Figure 7 This is a structural schematic diagram of a pulse ablation device provided in the first embodiment of the present invention.

[0048] Figure 8 This is a comsol verification image of the pulse ablation device provided in the first embodiment of the present invention.

[0049] Figure 9 This is a structural schematic diagram of a pulse ablation device provided in the second embodiment of the present invention.

[0050] Figure 10 This is a comsol verification image of the pulse ablation device provided in the second embodiment of the present invention.

[0051] Figure 11 This is a structural schematic diagram of a pulse ablation device provided in the third embodiment of the present invention.

[0052] Figure 12 This is a comsol verification image of the pulse ablation device provided in the third embodiment of the present invention.

[0053] Figure 13 This is a structural schematic diagram of a pulse ablation device provided in the fourth embodiment of the present invention.

[0054] Figure 14 This is a comsol verification image of the pulse ablation device provided in the fourth embodiment of the present invention.

[0055] Figure 15 The pulse ablation device provided in the first embodiment of the present invention verifies the image with a comsol of 100V~600V.

[0056] Figure 16 The pulse ablation device provided in the fourth embodiment of the present invention verifies the image with a comsol of 100V~600V.

[0057] Reference numerals:

[0058] 10. Pulse ablation device; 100. Catheter; 200. Electrode head; 300. Electrode assembly; 310. First electrode; 320. Second electrode; 400. Handle; 500. Multi-lumen tube; 510. First line cavity; 520. Second line cavity; 530. Third line cavity; 600. Fixing seat; 610. Main body; 611. Receiving cavity; 620. Protrusion; 700. Spring tube. DETAILED DESCRIPTION

[0059] To make the above-mentioned objects, features, and advantages of the present invention more clearly understood, the following detailed description of specific embodiments of the present invention is provided in conjunction with the accompanying drawings. The following description sets forth many specific details to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways than those described herein, and those skilled in the art may make similar modifications without departing from the scope of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0060] In this application, the “proximal end” may be considered as the end closer to the operator, and the “distal end” may be considered as the end farther away from the operator.

[0061] See also Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 and Figure 5In some embodiments, the present application provides a pulse ablation device 10, which includes a catheter 100, an electrode head 200, an electrode assembly 300, and a handle 400. The proximal end of the catheter 100 is connected to the handle 400, and the distal end of the catheter 100 is connected to the electrode head 200, and the electrode head 200 can be used to fix to the target tissue. The electrode assembly 300 includes a first electrode 310 and a second electrode 320 spaced apart from each other, and the first electrode 310 and the second electrode 320 are both arranged on the outer circumference of the distal end of the catheter 100. Among them, any two of the electrode head 200, the first electrode 310 and the second electrode 320 can discharge simultaneously and have opposite electrical properties.

[0062] Before describing the beneficial effects that can be achieved by the pulse ablation device 10 of the present application, it should be noted that, according to current literature and animal and human experiments, the ablation effect of pulse ablation depends on the combined effect of multiple factors, among which the electric field size is affected by the electrode size and spacing. The closer to the electrode, the stronger the electric field effect, and the electric field strength gradually decays with increasing distance from the electrode. The smaller the electrode size, the faster the field strength decays with increasing distance, and the tissue ablation effect also decreases accordingly.

[0063] Against this backdrop, the pulse ablation device 10 of the present application can achieve at least the following beneficial effects: The present application optimizes the electrode arrangement, with the spacing between the electrode head 200 and the multiple electrodes on the outer peripheral surface of the distal end of the catheter 100 being set. Any two of the electrode head 200, the first electrode 310, and the second electrode 320 can discharge simultaneously and with opposite electrical properties, thereby forming an effective electric field over a larger area, thereby achieving more uniform tissue ablation and avoiding the problem of insufficient local ablation. This also means making the ablation process more efficient, thereby reducing surgical time and patient pain, and helping to improve overall treatment efficiency.

[0064] Specifically, if Figure 2 、 Figure 3 and Figure 5As shown, in some embodiments, the pulse ablation device 10 further includes a first guidewire, a second guidewire, and a third guidewire (not shown), and a multi-lumen tube 500 disposed within the catheter 100. The multi-lumen tube 500 includes a first lumen 510, a second lumen 520, and a third lumen 530. The first guidewire is disposed within the first lumen 510, and its distal end is electrically connected to the first electrode 310. The second guidewire is disposed within the second lumen 520, and its distal end is electrically connected to the second electrode 320. The third guidewire is disposed within the third lumen 530, and its distal end is electrically connected to the electrode head 200. The independent lumen design within the multi-lumen tube 500 allows for a more orderly and compact arrangement of the guidewires, reduces the possibility of guidewire entanglement or kinking during surgery, ensures electrical isolation between the guidewires, avoids signal interference and short circuits, and improves the safety and reliability of the device. The material of the multi-lumen tube 500 may include but is not limited to PEBAX (polyether block polyamide), PTFE (polytetrafluoroethylene), TPU (thermoplastic polyurethane elastomer), PVC (polyvinyl chloride) and other polymer materials.

[0065] Specifically, if Figure 2 、 Figure 3 and Figure 6 As shown, in some embodiments, the pulse ablation device 10 further includes a fixing seat 600, which is provided at the distal end of the catheter 100, and the proximal end of the fixing seat 600 is fixed to the distal end of the multi-lumen tube 500, and the electrode head 200 is provided on the side of the fixing seat 600 facing away from the multi-lumen tube 500, and the third wire is passed through the fixing seat 600 and is electrically connected to the electrode head 200. Among them, the fixing seat 600 can be an insulating fixing seat 600 made of insulating material. The structural design of adding the fixing seat 600 and arranging the electrode head 200 on the side of the fixing seat 600 facing away from the multi-lumen tube 500 enables the electrode head 200 to be firmly mounted on the distal end of the catheter 100, ensuring that the electrode head 200 will not loosen or shift during operation, thereby improving the structural stability of the entire device and reducing errors caused by the movement of the catheter 100 during surgery. In addition, the distal end of the multi-lumen tube 500 is also connected to the fixing seat 600, which can also improve the stability of the relative position of the multi-lumen tube 500 in the catheter 100, and the third wire is passed through the fixing seat 600 and electrically connected to the electrode head 200, ensuring that electrical energy can be efficiently and reliably transmitted to the electrode head 200 for pulse ablation.

[0066] Specifically, if Figure 3 and Figure 4As shown, in some embodiments, the electrode head 200 is spiral-shaped and can be rotated under the drive of the catheter 100 to drill into and fix to the target tissue. The spiral electrode head 200 can be rotated under the drive of the catheter 100 to drill into the target tissue, thereby achieving a firm fixation. When the electrode head 200 drills into the target tissue, the electrode head 200 can abut against the target tissue around it and will not move axially or radially, allowing the electrode head 200 to be reliably fixed in the target tissue. After the ablation of a target tissue target point is completed, the electrode head 200 can be unscrewed through the catheter 100 to release the electrode head 200 from the target tissue, and then the electrode head 200 can be reused to drill into the next target point for ablation until all target tissue target points are ablated. This design not only ensures that the electrode head 200 will not be easily displaced during the ablation process, but also provides a better fixation effect in irregular or hard tissues. And because the electrode head 200 can penetrate deep into the target tissue, the ablation effect is enhanced. The spiral design increases the contact area between the electrode head 200 and the tissue, allowing electrical energy to be more evenly transmitted to the target area, thereby improving ablation efficiency and effectiveness. The electrode head 200 can be made of a conductive material, including but not limited to metals such as platinum-iridium alloy, gold, nickel-cobalt-chromium-molybdenum alloy, stainless steel, and titanium alloy. The electrode head 200 also acts as an electrode, capable of releasing pulse energy. After penetrating the target tissue, it works together with the electrode assembly 300 to achieve pulse ablation of the target tissue.

[0067] More specifically, if Figure 2 、 Figure 3 and Figure 6 As shown, in some embodiments, the fixing seat 600 includes a main body 610 and a protrusion 620 connected to the main body 610, the protrusion 620 is provided at the distal end of the main body 610, the electrode head 200 is fixedly sleeved on the outer circumference of the protrusion 620, and the proximal end of the main body 610 is provided with a receiving cavity 611, and the receiving cavity 611 is used to be fixed and communicated with the distal end of the multi-lumen tube 500. The protrusion 620 design of the fixing seat 600 provides a stable structure, so that the electrode head 200 can be firmly fixed. The proximal end of the main body 610 is provided with a receiving cavity 611, and the receiving cavity 611 design of the fixing seat 600 makes it easier to connect with the multi-lumen tube 500 and facilitates installation.

[0068] See also Figure 2 and Figure 3In some embodiments, the pulse ablation device 10 further includes a spring tube 700 disposed within the catheter 100. The spring tube 700 is sheathed around the outer circumference of the multi-lumen tube 500. The distal end of the multi-lumen tube 500 is exposed outside the spring tube 700 for connection to the fixing seat 600. The first electrode 310 and the second electrode 320 are located between the fixing seat 600 and the distal end of the spring tube 700. The distal end of the spring tube 700 is spaced apart from either the first electrode 310 or the second electrode 320 in the axial direction of the catheter 100. The spring tube 700 can provide additional structural support, enhance the structural stability of the catheter 100 and the multi-lumen tube 500, and reduce potential shaking or displacement during operation. The elastic properties of the spring tube 700 provide the catheter 100 with a certain degree of flexibility during operation, allowing it to better adapt to the complex anatomical structures in the human body and improve operational flexibility and precision. Because the spring tube 700 has a certain degree of elasticity, it can increase the transmission of torque to the distal end of the catheter 100 during proximal manipulation, thereby improving the maneuverability of the catheter 100 and facilitating the insertion of the electrode head 200 into the target tissue. Furthermore, the spring tube 700 is generally made of metal. Therefore, the design of spacing the distal end of the spring tube 700 from the first electrode 310 and the second electrode 320 (i.e., the distal end of the spring tube 700 is away from the electrodes) prevents the distal end of the spring tube 700 from becoming electrically conductive with the first electrode 310 and the second electrode 320 due to high voltage.

[0069] A variety of embodiments are further provided below to illustrate various structures and arrangements of the electrode assembly 300 , which is intended to further clarify the technical solution of the present application and does not indicate or imply any specific limitation on the electrode assembly 300 .

[0070] See also Figure 7 and Figure 8 In a first embodiment, the first electrode 310 and the second electrode 320 of the electrode assembly 300 are both annular and are sleeved on the outer circumference of the distal end of the catheter 100. The first electrode 310 and the second electrode 320 are spaced apart in the axial direction of the catheter 100. For example, the spacing between the first electrode 310 and the second electrode 320 in the axial direction of the catheter 100 can be about 4 mm. This is only an example, and other sizes are also possible. The annular electrode covers the outer circumference of the catheter 100, providing a larger contact area, which helps to improve the efficiency of electrical energy conduction and thus improve the ablation efficiency. The design of the annular electrode also makes the electric field distribution more uniform, which helps to improve the ablation effect, ensure that the target tissue can be subjected to a uniform electric field, and reduce the occurrence of unablated areas.

[0071] Furthermore, in the first embodiment, the thickness of the first electrode 310 in the radial direction of the catheter 100 is 0.05 mm-0.3 mm, and the width of the first electrode 310 in the axial direction of the catheter 100 is 0.75 mm-4.5 mm.

[0072] Furthermore, in the first embodiment, the thickness of the first electrode 310 in the radial direction of the catheter 100 is 0.1 mm, and the width of the first electrode 310 in the axial direction of the catheter 100 is 2 mm.

[0073] Furthermore, in the first embodiment, the thickness of the second electrode 320 in the radial direction of the catheter 100 is 0.05 mm to 0.3 mm, and the width of the second electrode 320 in the axial direction of the catheter 100 is 0.75 mm to 4.5 mm.

[0074] Furthermore, in the first embodiment, the thickness of the second electrode 320 in the radial direction of the catheter 100 is 0.1 mm, and the width of the second electrode 320 in the axial direction of the catheter 100 is 2 mm.

[0075] See also Figure 9 and Figure 10 In the second embodiment, the first electrode 310 and the second electrode 320 are both tile-shaped and are spaced apart on the outer peripheral surface of the catheter 100 along the circumference of the catheter 100, and the positions of the first electrode 310 and the second electrode 320 in the axial direction of the catheter 100 correspond to each other. Such an arrangement can be roughly considered that the projections of the first electrode 310 and the second electrode 320 in the radial direction of the catheter 100 are aligned. The tile-shaped first electrode 310 and the second electrode 320 are spaced apart along the circumference of the catheter 100, providing a larger contact area and ensuring a uniform distribution of the electric field in the target area, which helps to improve the efficiency of electric energy conduction. Since the positions of the first electrode 310 and the second electrode 320 in the axial direction correspond to each other, more precise electric field positioning can be achieved, making the electric field between the two electrodes stronger and more concentrated, and being able to conduct electric energy more effectively, thereby improving the ablation efficiency.

[0076] Furthermore, in the second embodiment, the angle of the first electrode 310 in the circumferential direction of the catheter 100 is 45°~160°, the thickness of the first electrode 310 in the radial direction of the catheter 100 is 0.05mm-0.3mm, and the width of the first electrode 310 in the axial direction of the catheter 100 is 1.5mm-12mm.

[0077] Furthermore, in the second embodiment, the angle of the second electrode 320 in the circumferential direction of the catheter 100 is 45°~160°, the thickness of the second electrode 320 in the radial direction of the catheter 100 is 0.05mm-0.3mm, and the width of the second electrode 320 in the axial direction of the catheter 100 is 1.5mm-12mm.

[0078] See also Figure 11 and Figure 12In the third embodiment, both the first electrode 310 and the second electrode 320 are tile-shaped and spaced apart along the circumference of the catheter 100 on the outer circumference of the catheter 100. Furthermore, the first electrode 310 and the second electrode 320 are at least partially offset in the axial direction of the catheter 100. This arrangement generally means that the projections of the first electrode 310 and the second electrode 320 in the radial direction of the catheter 100 only partially overlap and are offset. Because the first electrode 310 and the second electrode 320 are at least partially offset in the axial direction of the catheter 100, the range of action of the electric field is expanded, covering a larger target area and enhancing the ablation effect.

[0079] Furthermore, in the third embodiment, the angle of the first electrode 310 in the circumferential direction of the catheter 100 is 45°~160°, the thickness of the first electrode 310 in the radial direction of the catheter 100 is 0.05mm-0.3mm, and the width of the first electrode 310 in the axial direction of the catheter 100 is 1.5mm-12mm.

[0080] Furthermore, in the third embodiment, the angle of the second electrode 320 in the circumferential direction of the catheter 100 is 45°~160°, the thickness of the second electrode 320 in the radial direction of the catheter 100 is 0.05mm-0.3mm, and the width of the second electrode 320 in the axial direction of the catheter 100 is 1.5mm-12mm.

[0081] See also Figure 13 and Figure 14 In the fourth embodiment, both the first electrode 310 and the second electrode 320 are flexible electrodes. They are helically shaped and interlaced around the outer circumference of the distal end of the catheter 100. This structural design ensures a more uniform distribution of the electric field within the target tissue, helping to improve the uniformity and thoroughness of ablation. Even at low voltages, the helical structure maintains an effective ablation range, consistently ablating surrounding tissue. The ablation range also increases with increasing voltage.

[0082] It should be noted that the present application conducts comsol verification on the arrangement of the electrode assembly 300 of the first embodiment, the second embodiment, the third embodiment and the fourth embodiment respectively, referring to Figure 8 、 Figure 10 、 Figure 12 and Figure 14 The comsol image shows that under the high voltage of 2000V, the ablation effect of the electrode arrangement in different embodiments is excellent. It is judged that the above electrode arrangement is acceptable. Figure 15 and Figure 16As shown, the first and fourth embodiments were further explored, and both were verified by COMSOL at low voltage (below 800V). Experiments were carried out in COMSOL at 100V~600V in sequence. The traditional electrode arrangement of the first embodiment was verified to be unable to achieve effective ablation. Only with the gradual increase of voltage can ablation be achieved between the two electrodes. The new electrode arrangement scheme - the fourth embodiment, can maintain an effective ablation range even at low voltage. The spiral structure can always ablate the surrounding tissues, and the ablation range also increases with the increase of voltage, which has a better ablation effect than the electrode arrangement scheme of the first embodiment.

[0083] It should be emphasized that the present application does not specifically limit the number of electrode assemblies 300, and the number and arrangement of electrode assemblies 300 can be flexibly adjusted according to actual needs. Figure 12 In the third embodiment shown, the number of electrode assemblies 300 is set to two, and the two sets of electrode assemblies 300 are spaced apart and distributed along the axial direction of the catheter 100. Similarly, the first embodiment, the second embodiment, the fourth embodiment, or other embodiments not shown can also be implemented in the same manner, and the number is not limited to two, but can also be three, four, or more.

[0084] The technical features of the above-mentioned embodiments can be combined arbitrarily. In order to make the description concise, not all possible combinations of the technical features in the above-mentioned embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0085] The above-described embodiments merely represent several implementations of the present invention. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the utility model patent. It should be noted that a person skilled in the art would be able to make various modifications and improvements without departing from the concept of the present invention, and these modifications and improvements fall within the scope of protection of the present invention. Therefore, the scope of protection of the present utility model patent shall be determined by the appended claims.

[0086] In the description of the present invention, it should be understood that the terms "axial", "radial", "circumferential", "length", "width", "thickness", "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like to indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0087] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of the technical features being referred to. Thus, a feature specified as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of this utility model, "plurality" means at least two, such as two, three, etc., unless otherwise specifically defined.

[0088] In the present invention, unless otherwise expressly specified or limited, when a first feature is "above" or "below" a second feature, it may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediary. Furthermore, when a first feature is "above," "above," or "above" a second feature, it may mean that the first feature is directly above or diagonally above the second feature, or simply means that the first feature is at a higher level than the second feature. When a first feature is "below," "below," or "below" a second feature, it may mean that the first feature is directly below or diagonally below the second feature, or simply means that the first feature is at a lower level than the second feature.

[0089] In this utility model, unless otherwise specified or limited, the terms "installed," "connected," "connect," "fixed," etc. should be understood in a broad sense. For example, they can refer to fixed connection, detachable connection, or integration; mechanical connection, electrical connection; direct connection, or indirect connection through an intermediate medium; internal communication between two components, or interaction between two components, unless otherwise specified. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on specific circumstances.

[0090] It should be noted that when an element is referred to as being "provided on," "fixed on," or "disposed on" another element, it may be directly on the other element or there may be an intermediate element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be an intermediate element. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only implementation methods.

[0091] In the description of this specification, the description with reference to the terms "one embodiment", "other implementation methods", etc. means that the specific features, structures, materials or features described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic descriptions of the above terms do not necessarily refer to the same embodiment or example. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which this application belongs. The terms used herein in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application.

Claims

1. A pulse ablation device, characterized in that: include: catheter; a multi-lumen tube, disposed in the catheter, wherein a first line lumen, a second line lumen, and a third line lumen are formed in the multi-lumen tube; A spring tube is provided in the catheter and sleeved on the outer circumference of the multi-lumen tube; A fixing seat is provided at the distal end of the catheter, wherein the proximal end of the fixing seat is fixed to the distal end of the multi-lumen tube; an electrode head, disposed on a side of the fixing seat facing away from the multi-lumen tube and used for fixing to a target tissue; an electrode assembly, comprising a first electrode and a second electrode spaced apart from each other, wherein the first electrode and the second electrode are both disposed on an outer circumferential surface of the distal end of the catheter; a first guide wire disposed in the first wire lumen and having a distal end electrically connected to the first electrode; a second guide wire disposed in the second wire lumen and having a distal end electrically connected to the second electrode; a third wire disposed in the third wire cavity and having a distal end electrically connected to the electrode head; The first electrode and the second electrode are located between the fixing seat and the distal end of the spring tube, and the distal end of the spring tube is spaced apart from either the first electrode or the second electrode in the axial direction of the catheter. Any two of the electrode head, the first electrode and the second electrode can discharge simultaneously and have opposite electrical properties.

2. The pulse ablation device according to claim 1, characterized in that The fixing seat includes a main body and a protrusion connected to the main body, the protrusion is arranged at the distal end of the main body, the electrode head is fixedly sleeved on the outer circumference of the protrusion, and a receiving cavity is opened at the proximal end of the main body, and the receiving cavity is used to be fixed and connected with the distal end of the multi-lumen tube.

3. The pulse ablation device according to claim 1, characterized in that: The distal end of the third wire is passed through the fixing seat and is electrically connected to the electrode head; And / or, the electrode head is spiral-shaped and can be rotated by the catheter to drill into and fix to the target tissue; And / or, the distal end of the multi-lumen tube is exposed from the spring tube to be connected to the fixing seat.

4. The pulse ablation device according to any one of claims 1 to 3, characterized in that: The first electrode and the second electrode are both annular and sleeved on the outer circumference of the distal end of the catheter. The first electrode and the second electrode are spaced apart in the axial direction of the catheter.

5. The pulse ablation device according to claim 4, characterized in that: The thickness of the first electrode in the radial direction of the catheter is 0.05 mm to 0.3 mm; And / or, the width of the first electrode in the axial direction of the catheter is 0.75 mm-4.5 mm; and / or, the thickness of the second electrode in the radial direction of the catheter is 0.05 mm-0.3 mm; And / or, the width of the second electrode in the axial direction of the catheter is 0.75 mm-4.5 mm.

6. The pulse ablation device according to any one of claims 1 to 3, characterized in that: The first electrode and the second electrode are both tile-shaped and are arranged at intervals on the outer peripheral surface of the catheter along the circumference of the catheter.

7. The pulse ablation device according to claim 6, characterized in that: The first electrode and the second electrode are located at corresponding positions in the axial direction of the catheter.

8. The pulse ablation device according to claim 6, characterized in that: The positions of the first electrode and the second electrode in the axial direction of the catheter are at least partially staggered.

9. The pulse ablation device according to claim 6, characterized in that: The angle of the first electrode in the circumferential direction of the catheter is 45° to 160°; And / or, the thickness of the first electrode in the radial direction of the catheter is 0.05 mm-0.3 mm; And / or, the width of the first electrode in the axial direction of the catheter is 1.5 mm-12 mm; and / or, the angle of the second electrode in the circumferential direction of the catheter is 45° to 160°; and / or, the thickness of the second electrode in the radial direction of the catheter is 0.05 mm-0.3 mm; And / or, the width of the second electrode in the axial direction of the catheter is 1.5 mm-12 mm.

10. The pulse ablation device according to any one of claims 1 to 3, characterized in that: The first electrode and the second electrode are both spiral-shaped and staggeredly coiled on the outer circumference of the distal end of the catheter; And / or, both the first electrode and the second electrode are flexible electrodes.

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