Self-heating microneedle patch
Through the design of self-heating microneedle patches, the microneedle patches are heated by heating materials, which solves the problem of low drug delivery efficiency, achieves efficient drug delivery and cost control, and expands the scope of application.
Patent Information
- Application Number
- CN202422273046.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-18
- Publication Date
- 2025-09-16
- Estimated Expiration
- 2034-09-18
AI Technical Summary
Existing microneedle patches are slow to deliver drugs beneath the skin, and the heating equipment is expensive, limiting their application and increasing treatment costs.
The self-heating microneedle patch design is adopted. By filling the holding dish with heating material, sealing it with a closed lid and adding water to make it heat up, the heat is transferred to the microneedle patch to accelerate the entry of the drug into the human body. Combined with soluble materials such as hyaluronic acid, the drug is quickly released under the action of heat.
It significantly improves the drug delivery efficiency, shortens the drug onset time, reduces treatment costs and expands the scope of application.
Smart Images
Figure CN223336610U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of microneedle patches, in particular to a self-heating microneedle patch. Background Art
[0002] Microneedle patches are an emerging drug delivery technology that has been widely used in the medical and beauty industries in recent years. By setting tiny needles on the patch, drugs are delivered directly to the dermis under the skin. The needles of microneedle patches are very small and are usually made of biodegradable materials. They can contact the epidermis of the skin but not the nerve endings, so they will not cause obvious pain. This method can effectively avoid the degradation of epidermal drugs in the digestive tract or reduce the pain and uneven drug delivery caused by traditional injections.
[0003] Since microneedle patches deliver drugs directly to the bottom of the skin through tiny needles, the drugs need to pass through multiple layers of the skin to enter the blood circulation or act on the lesion site. However, the barrier effect of the skin will cause the drugs to enter the human body more slowly, affecting the rapid effect of the drugs. To solve this problem, microneedle patches are often used in combination with heating equipment to improve the efficiency of drug delivery. However, the heating equipment currently used in clinical practice is expensive. This combined treatment method will increase the patient's treatment costs on the one hand, and on the other hand, it will limit the application scope of microneedle patch technology. Utility Model Content
[0004] In view of the deficiencies in the prior art, the present invention provides a self-heating microneedle patch, which solves the problem in the prior art that the microneedle patch is slow in delivering drugs to the skin.
[0005] According to an embodiment of the present utility model, a self-heating microneedle patch includes a holding dish and a fixing member. The top of the holding dish is open, and a closing cover is detachably provided at the opening. The holding dish contains a heating material. A mounting ring is fixedly provided at the bottom of the holding dish, and a microneedle patch is replaceably provided in the mounting ring. The fixing member is arranged on the outer wall of the holding dish, and the fixing assembly is used to fix the microneedle patch to the human body.
[0006] Compared with the existing technology, the present invention has the following beneficial effects: by filling the holding dish with heating material, closing the holding dish with a closing cover, and placing the microneedle patch in the mounting ring at the bottom of the holding dish, when in use, after the microneedle patch and the holding dish are fixed to the affected part of the human body through the fixing parts, the closing cover is opened and water is added to allow the heating material to generate heat. After the heat is transferred to the microneedle patch, the medicine loaded on the microneedle patch can quickly enter the human body, thereby significantly improving the drug administration efficiency of the microneedle patch and shortening the onset time of the medicine.
[0007] Furthermore, the bottom of the inner wall of the receiving dish is provided with a curved surface.
[0008] Furthermore, the closing cover is threadedly connected to the receiving vessel.
[0009] Furthermore, it also includes a spring. The inner wall of the mounting ring is provided with a plurality of mounting grooves at equal intervals along its circumferential direction. A ball is slidably provided in each mounting groove. Each ball is fixed with one end of a spring facing one side of the mounting groove, and the other end of the spring is fixed to the inner wall of the mounting groove.
[0010] Furthermore, the fixing member is a suction cup, which is fixed on the outer wall of the containing dish.
[0011] As another embodiment of the present invention, the fixing member is a strap, and both ends of the strap are respectively fixedly arranged on both sides of the outer wall of the container. BRIEF DESCRIPTION OF THE DRAWINGS
[0012] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the present utility model.
[0013] Figure 2 It is a bottom view of an embodiment of the present utility model.
[0014] Figure 3 This is a cross-sectional structural diagram of an embodiment of the present utility model.
[0015] Figure 4 This is a schematic diagram of ball installation according to an embodiment of the present invention.
[0016] Figure 5 This is a schematic diagram of the overall structure of another embodiment of the present utility model.
[0017] In the above drawings: 1. Container; 2. Closing cover; 3. Heating material; 4. Mounting ring; 5. Microneedle patch; 6. Arc surface; 7. Spring; 8. Ball; 9. Suction cup; 10. Strap. DETAILED DESCRIPTION
[0018] The technical solution of the present invention is further described below with reference to the accompanying drawings and embodiments.
[0019] like Figure 1As shown in FIG3 , an embodiment of the utility model provides a self-heating microneedle patch, comprising a holding dish 1 and a fixing member. The top of the holding dish 1 is open, and a closing cover 2 is detachably provided at the opening. The holding dish 1 contains a heating material 3, and a mounting ring 4 is fixedly provided at the bottom of the holding dish 1. A microneedle patch 5 is replaceably provided in the mounting ring 4. The fixing member is provided on the outer wall of the holding dish 1, and the fixing assembly is used to fix the microneedle patch 5 to the human body. In this embodiment, the microneedle patch 5 is composed of a base and a needle tip. The needle tip of the microneedle patch 5 is made of a soluble material such as hyaluronic acid (HA) as a carrier, which can be loaded with the required drug. The carrier material such as hyaluronic acid can be accelerated to dissolve when heated, so that the drug in the needle tip is quickly released into the wound to play a role. The heating material 3 in the holding dish 1 is mainly composed of calcium oxide, reduced iron powder, activated carbon, sodium chloride and anhydrous magnesium sulfate (a mixture of iron powder and activated carbon can also be used. After the proportion is adjusted, the maximum heating temperature reaches 50-60°C and the duration can reach 2-3 hours). When in use, the microneedle patch 5 is placed in the mounting ring 4. The mounting ring 4 plays a role in positioning the microneedle patch 5 and prevents the microneedle patch 5 from relative displacement with the holding dish 1. The needle tip of the microneedle patch 5 faces outward, and tweezers can be used to assist in placing it, and then the end of the microneedle patch 5 with the needle tip is placed. The device is placed in close contact with the affected area of the human body, and then the container 1 and the microneedle patch 5 are fixed to the skin of the human body by a fixing member. The closing cover 2 is then opened. The closing cover 2 can be a polyethylene film (a polyethylene film is suitable for disposable use of the device). A small amount of water is added to the container 1 to make the substances in the container 1 react and release heat. Preferably, the bottom of the container 1 is made of a heat-conducting material (such as copper, aluminum, graphite sheet, etc., which can be selected from existing heat-conducting materials). After the heat is transferred to the microneedle patch 5, the microneedle patch 5 is heated. The heat promotes the separation of carrier materials such as hyaluronic acid at the needle tip of the microneedle patch 5, so that the drug loaded therein can quickly enter the human body. At the same time, the microneedle patch 5 heats the skin, which can dilate blood vessels, increase local blood flow, improve skin permeability, enhance drug penetration and absorption efficiency, and thus greatly improve the efficiency of transdermal drug delivery. Preferably, by proportioning the heating material, the heating temperature is made between 50°C and 60°C, so that the antibacterial effect on the wound can be achieved without damaging normal cells.
[0020] like Figure 3 As shown, further, the bottom of the inner wall of the container 1 is provided with an arc surface 6. The bottom of the inner wall of the container 1 is provided with an arc surface 6, which can facilitate the cleaning of the container 1 and avoid the situation where dead corners are not cleaned properly.
[0021] Furthermore, the closure cover 2 is threadedly connected to the container 1. In this embodiment, a rotating handle is provided on the closure cover 2 for convenient rotation. By detachably connecting the closure cover 2 to the opening of the container 1 through threads, the heating material 3 in the container 1 can be easily replaced, thereby achieving the reuse of the container 1 and saving medical costs.
[0022] like Figure 3 and 4 As shown, further, a spring 7 is included. The inner wall of the mounting ring 4 is provided with a plurality of mounting grooves at equal intervals along its circumferential direction. A ball 8 is slidably mounted within each mounting groove. Each ball 8 is fixed to one end of a spring 7 facing one side of the mounting groove, and the other end of the spring 7 is fixed to the inner wall of the mounting groove. Under the action of the spring 7, one side of each ball 8 extends out of the mounting groove. After the microneedle patch 5 is placed into the mounting ring 4, the base portion can be restrained by the ball 8, preventing it from falling out of the mounting ring 4. The presence of the spring 7 also makes it easier to insert the base portion between the ball 8 and the bottom of the holding dish 1.
[0023] like Figure 1 As shown in FIG4 , the fixing member is a suction cup 9, which is fixed to the outer wall of the container 1. Specifically, the suction cup 9 is made of silicone or polyurethane, which makes the suction cup 9 soft and elastic, can fit well on the skin surface, and provides effective adsorption, allowing medical personnel to quickly fix the microneedle patch 5 and the container 1 to the human body.
[0024] like Figure 5 As shown, as another embodiment of the present invention, the fixing member is a strap 10, and the two ends of the strap 10 are respectively fixedly arranged on the two sides of the outer wall of the container 1. Specifically, the strap 10 is made of an elastic material (such as spandex, nylon, etc.), which facilitates the device to be attached to the human body and fixes the device to the human body to prevent it from slipping off the human skin. Preferably, the strap 10 can also be provided with an adjustment buckle for adjusting the length of the strap 10 (similar to the adjustment buckle for adjusting the length of a backpack strap or the adjustment buckle for adjusting the length of a belt). The adjustment buckle is existing in the art and will not be described in detail here.
[0025] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model and are not limiting. Although the utility model is described in detail with reference to the preferred embodiments, ordinary technicians in this field should understand that the technical solution of the utility model can be modified or replaced by equivalents without departing from the purpose and scope of the technical solution of the utility model, which should be included in the scope of the claims of the utility model.
Claims
1. A self-heating microneedle patch, characterized by: include: A holding dish (1) is provided, wherein the top of the holding dish (1) is open and a detachable closing cover (2) is provided at the opening. A heating material (3) is accommodated in the holding dish (1). A mounting ring (4) is fixedly provided at the bottom of the holding dish (1), and a microneedle patch (5) is replaceably provided in the mounting ring (4). A fixing member is arranged on the outer wall of the containing dish (1), and the fixing assembly is used to fix the microneedle patch (5) to the human body.
2. A self-heating microneedle patch according to claim 1, characterized in that: The bottom of the inner wall of the containing dish (1) is provided with an arc surface (6).
3. The self-heating microneedle patch according to claim 1, wherein: The closing cover (2) is threadedly connected to the receiving container (1).
4. The self-heating microneedle patch according to claim 1, wherein: The invention also includes a spring (7). The inner wall of the mounting ring (4) is provided with a plurality of mounting grooves at equal intervals along its circumferential direction. A ball (8) is slidably provided in each mounting groove. One end of each ball (8) is fixedly provided with a spring (7) toward one side of the mounting groove, and the other end of the spring (7) is fixed to the inner wall of the mounting groove.
5. The self-heating microneedle patch according to claim 1, wherein: The fixing member is a suction cup (9), and the suction cup (9) is fixedly arranged on the outer wall of the containing dish (1).
6. The self-heating microneedle patch according to claim 1, characterized in that: The fixing member is a binding belt (10), and the two ends of the binding belt (10) are respectively fixedly arranged on the two sides of the outer wall of the containing dish (1).