Blood bias flow testing device of blood purifier

Abstract

The utility model provides a blood bias flow testing device of a blood purifier. The blood bias flow testing device comprises a testing rack, a sampler and a plurality of flow meters, the test bench is used for vertically fixing the blood purifier, so that the second end of the blood purifier faces downwards; the sampler comprises a plurality of connecting pipes and is detachably arranged at the second end of the blood purifier; the first end of the connecting pipe is communicated with a membrane wire; the first end of the flow meter is connected with the second end of the connecting pipe and used for detecting the flow of the test liquid in the corresponding connecting pipe. Therefore, the flow data of the test liquid in each area in the blood purifier can be obtained, the bias flow degree of the test liquid in the blood purifier can be obtained by analyzing the flow data, and a reference is provided for optimal design of the structure of the blood purifier. The problem that the bias flow degree of blood in the blood purifier cannot be obtained in the prior art is solved.

Description

Technical Field

[0001] The present application relates to the field of testing technology, and in particular to a blood deviation flow testing device for a blood purifier. Background Art

[0002] In a blood purifier, blood tends to flow toward areas of less resistance. Specifically, blood flows more easily near the central axis of a membrane bundle (composed of multiple membrane filaments) than near the edges. This phenomenon is known as bias flow. When bias flow occurs, the blood flow rate changes, leading to a decrease in solute removal efficiency. Therefore, the degree of blood bias flow is a key indicator of the effectiveness of a blood purifier design.

[0003] In the prior art, some methods are used to characterize the flow state of the liquid in the blood purifier. For example, the flow state of the dialysate can be characterized by X-ray CT. However, there is no relevant method to characterize the uniformity of the blood flow in the blood purifier, so it is impossible to obtain the degree of blood deviation in the blood purifier. Utility Model Content

[0004] In view of this, the present application provides a blood deviation flow testing device for a blood purifier to solve the problem in the prior art that the degree of blood deviation in the blood purifier cannot be obtained.

[0005] To achieve the above objectives, this application provides the following technical solutions:

[0006] The present application discloses a blood flow deviation test device for a blood purifier, wherein the blood purifier has a test liquid inlet and a test liquid outlet, and the blood purifier includes a plurality of membrane filaments fixed by sealing glue, the test liquid inlet is located at a first end of the blood purifier, and the test liquid outlet is located at a second end of the blood purifier. The blood flow deviation test device includes: a test bench, a sampler, and a plurality of flow meters;

[0007] The test bench is used to vertically fix the blood purifier so that the second end of the blood purifier faces downward;

[0008] The sampler is detachably mounted on the second end of the blood purifier, and comprises a plurality of connecting tubes, wherein the first ends of the connecting tubes are used to communicate with the membrane wire;

[0009] The first end of the flow meter is connected to the second end of the connecting pipe and is used to detect the flow rate of the test liquid in the corresponding connecting pipe.

[0010] Optionally, in the above-mentioned device, the test bench includes a vertical rod, a platform base, a first lifter and a fixing clamp;

[0011] The vertical rod is installed on the platform base;

[0012] The first lifter is mounted on the vertical rod;

[0013] One end of the fixing clamp is connected to the first lifter, and the other end of the fixing clamp has a clamping structure, and the clamping structure is used to fix the blood purifier;

[0014] The first lifter is used to control the lifting and lowering of the blood purifier.

[0015] Optionally, in the above-mentioned device, the sampler is a circular sampler, which includes a circular cover body, and the inner side of the circular cover body is provided with a thread shape that matches the thread shape of the blood purifier shell, so that when the circular sampler is set at the second end of the blood purifier, the end face of the connecting tube is tightly fitted with the end face of the blood purifier; the circular cover body is provided with a connecting hole for connecting the catheter.

[0016] Optionally, the above device further comprises a first conduit and a container;

[0017] The first end of the first conduit is connected to the connecting hole of the circular sampler;

[0018] The container is arranged on the platform base and is used for receiving the test liquid flowing out of the first conduit.

[0019] Optionally, the above device further includes a second catheter;

[0020] The first end of the second conduit is connected to the second end of the flow meter;

[0021] The container is also used to receive the test liquid flowing out of the second catheter.

[0022] Optionally, in the above-mentioned device, the test bench includes a second lifter;

[0023] The sampler is a square sampler, and the square sampler includes a square cover;

[0024] The second lifter is connected to one end of the square sampler and is used to control the lifting of the square sampler.

[0025] Optionally, the above device further comprises a third conduit and a container;

[0026] The first end of the third conduit is connected to the second end of the flow meter;

[0027] The container is arranged on the platform base and is used for receiving the outflowing test liquid.

[0028] Optionally, the above-mentioned device further comprises a chromatography data processing system;

[0029] The chromatography data processing system is communicatively connected with the flow meter;

[0030] The chromatography data processing system is used to record the data in the flow meter and calculate the relative standard deviation of the blood purifier based on the data.

[0031] Optionally, in the above-mentioned device, the area where the connecting tube of the circular sampler is provided is not larger than the test liquid outlet area of ​​the blood purifier.

[0032] Optionally, in the above-mentioned device, the area where the connecting tube of the square sampler is provided is not smaller than the test liquid outlet area of ​​the blood purifier.

[0033] It can be seen from the above technical solution that the blood deviation test device for the blood purifier provided by the present application includes: a test bench, a sampler and a plurality of flow meters; the test bench is used to vertically fix the blood purifier so that the second end of the blood purifier faces downward; the sampler includes a plurality of connecting tubes, and the sampler is detachably arranged at the second end of the blood purifier; the first end of the connecting tube is used to communicate with the membrane filament; the first end of the flow meter is connected to the second end of the connecting tube, and is used to detect the flow rate of the test liquid in the corresponding connecting tube. It can be seen that the present application can obtain the flow data of the test liquid in the membrane filament in different areas of the test blood purifier, and the deviation degree of the test liquid in the blood purifier can be obtained by analyzing the flow data, which solves the problem that the deviation degree of blood in the blood purifier cannot be obtained in the prior art. Furthermore, the deviation degree of the test liquid in the blood purifier can also provide a reference for the optimized design of the blood purifier structure. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are merely embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without any creative work.

[0035] Figure 1 This is a schematic diagram of the structure of the blood purifier in this application;

[0036] Figure 2 A schematic diagram of a blood bias flow testing device for a blood purifier disclosed in an embodiment of the present application;

[0037] Figure 3 A schematic diagram of the liquid flow in the blood purifier in this application;

[0038] Figure 4 This is a schematic structural diagram of a circular sampler disclosed in an embodiment of the present application;

[0039] Figure 5 A schematic diagram of another blood bias flow testing device for a blood purifier disclosed in an embodiment of the present application;

[0040] Figure 6 This is a schematic structural diagram of a square sampler disclosed in an embodiment of the present application. DETAILED DESCRIPTION

[0041] The following will be combined with the drawings in the embodiments of this application to clearly and completely describe the technical solutions in the embodiments of this application. Obviously, the embodiments described are only part of the embodiments of this application, not all of the embodiments. Based on the embodiments in this application, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0042] In this application, the terms "comprises," "comprising," or any other variations thereof are intended to encompass non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus. In the absence of further limitations, an element defined by the phrase "comprising a ..." does not preclude the presence of additional identical elements in the process, method, article, or apparatus that includes the element.

[0043] Furthermore, in this document, relational terms such as first and second, etc. are used merely to distinguish one entity or operation from another entity or operation, but do not necessarily require or imply any actual relationship or order between these entities or operations.

[0044] As can be seen from the background technology, in the existing technology, some methods are used to characterize the flow state of the liquid in the blood purifier. For example, the flow state of the dialysate can be characterized by X-ray CT method. However, there is no relevant method to characterize the uniformity of the blood flow in the blood purifier, so the degree of blood deviation in the blood purifier cannot be obtained.

[0045] In view of this, the present application provides a blood deviation flow testing device for a blood purifier to solve the problem in the prior art that the degree of blood deviation in the blood purifier cannot be obtained.

[0046] The present invention provides a blood flow deviation test device for a blood purifier. Figure 1 and Figure 2As shown, the blood purifier 3 has a test liquid inlet 1 and a test liquid outlet 2. The test liquid is used to replace blood for testing. The blood purifier 3 includes a plurality of membrane filaments 17 fixed in the shell of the blood purifier 3 by a sealing glue 7. The membrane filaments 17 can be hollow fiber membrane filaments. The test liquid inlet 1 is located at the first end of the blood purifier, and the test liquid outlet 2 is located at the second end of the blood purifier. At the same time, the blood purifier 3 also has a dialysate inlet and a dialysate outlet. The flow directions of the test liquid and the dialysate in the blood purifier 3 are as shown in FIG. Figure 3 The covers at the test liquid inlet 1 and the test liquid outlet 2 of the blood purifier 3 are detachable.

[0047] The blood deviation flow testing device of the blood purifier comprises: a test stand 6 , a sampler 8 and a plurality of flow meters 11 .

[0048] The test stand 6 is used to vertically fix the blood purifier 3 so that the second end of the blood purifier 3 faces downward, thereby ensuring that the test liquid enters from the test liquid inlet 1 and flows out from the test liquid outlet 2. The material of the test stand 6 can be selected according to actual conditions and can be an iron stand or other materials.

[0049] The sampler 8 includes a circular cover 14 and a plurality of connecting tubes 15. The sampler 8 is detachably mounted on the second end of the blood purifier 3. When a blood flow deviation test is required, the cover at the test fluid outlet 2 of the blood purifier 3 is removed and the sampler 8 is mounted on the second end of the blood purifier 3. The sampler 8 can be removed when no further testing is required or the sampler is replaced.

[0050] The structure of the sampler 8 is not limited to Figure 2 In some optional embodiments, the sampler 8 may not include Figure 2 The circular cover 14 shown only includes a plurality of connecting tubes 15 .

[0051] The first end of the connecting tube 15 is used to communicate with the membrane filament 17. When the connecting tube 15 is connected to the membrane filament 17, the end face of the connecting tube 15 and the sealing glue 7 on the end face of the blood purifier 3 are tightly fitted or one end of the connecting tube 15 is inserted into the sealing glue 7, so that the test liquid in various areas of the blood purifier 3 will flow into the connecting tube 15 of the sampler 8. The connecting tube 15 and the membrane filament 17 are connected to at least the central axis area and the edge area of ​​the membrane bundle of the blood purifier 3, so as to detect the flow rate of the blood purifier 3 in the central axis area of ​​the membrane bundle and the flow rate in the edge area. By analyzing the flow data of different areas, it is possible to detect whether there is a flow deviation phenomenon in the blood purifier 3. For example, a number of connecting tubes 15 are set in the central axis area of ​​the membrane bundle, and a number of connecting tubes 15 are also set in the edge areas in different directions.

[0052] The first end of the flowmeter 11 is connected to the second end of the connecting tube 15, and is used to detect the flow rate of the test liquid in the corresponding connecting tube. By performing data analysis on the test liquid flow rate in each connecting tube detected, the relative standard deviation of the test liquid flow rate in each connecting tube can be obtained. The smaller the relative standard deviation, the smaller the degree of blood deviation, which indicates that the design of the blood purifier is more reasonable. Generally speaking, a relative standard deviation of less than 10% is usually considered to be a low degree of variation and is often used as one of the standards for data quality control. This means that the degree of variation in the data set is relatively small and the data is relatively stable. For certain specific industries or experimental requirements, a stricter relative standard deviation requirement range may be set, such as less than 5%. Therefore, a relative standard deviation threshold can be set in advance, such as 7%. When the calculated relative standard deviation is less than 7%, it means that the blood purifier has a small degree of blood deviation and a more reasonable structural design. Otherwise, it means that the blood purifier has a large degree of blood deviation and an unreasonable structural design, which needs to be improved.

[0053] The blood deviation test device for the blood purifier provided by the present application includes: a test bench, a sampler and a plurality of flow meters; the test bench is used to vertically fix the blood purifier so that the second end of the blood purifier faces downward; the sampler includes a plurality of connecting tubes, and the sampler is detachably arranged at the second end of the blood purifier; the first end of the connecting tube is used to communicate with the membrane filament; the first end of the flow meter is connected to the second end of the connecting tube, and is used to detect the flow rate of the test liquid in the corresponding connecting tube. It can be seen that the present application can obtain the flow data of the test liquid in each area of ​​the test blood purifier, and by analyzing the flow data, the deviation degree of the test liquid in the blood purifier can be obtained, which provides a reference for the optimal design of the blood purifier structure. It solves the problem that the deviation degree of blood in the blood purifier cannot be obtained in the prior art.

[0054] Optionally, in another embodiment of the present application, reference may be made to Figure 2 The test bench includes a vertical rod 21, a platform base 22, a first lifter 5 and a fixing clamp 4.

[0055] The vertical rod 21 is installed on the platform base 22 , and the first lifter 5 can be installed on the vertical rod 21 .

[0056] One end of the fixing clamp 4 is connected to the first lifter 5, and the other end of the fixing clamp 4 has a clamping structure, which is used to fix the blood purifier 3. The first lifter 5 contains a rotating nut, and the tightness of the first lifter 5 is adjusted by rotating the nut. When the adjustment is loose, the first lifter 5 can be moved up and down, and the nut can be tightened when it needs to be fixed.

[0057] The first lifter 5 is used to control the lifting and lowering of the blood purifier 3 , so that when the height of the blood purifier 3 needs to be adjusted, it can be adjusted through the first lifter 5 .

[0058] Optionally, in another embodiment of the present application, reference may be made to Figure 2 The sampler is a circular sampler, which includes a circular cover 14 and a plurality of connecting tubes 15. Figure 4 As shown, the multiple connecting tubes 15 can be 5-9 mm stainless steel catheters with sharp ends.

[0059] The inner side of the circular cover 14 is provided with a thread shape that matches the thread shape of the outer shell of the blood purifier 3, so that when the circular sampler is set at the second end of the blood purifier 3, the end face of the connecting tube 15 is tightly fitted with the end face of the blood purifier 3.

[0060] A connecting hole 18 for connecting a conduit is provided near the edge of the circular cover 14 and can be used to connect with other connecting conduits.

[0061] Alternatively, in another embodiment of the present application, the area of ​​the circular sampler where the connecting tube 15 is provided is no larger than the test fluid outlet area of ​​the blood purifier 3. This allows for the blood flow deviation test to be performed only on certain areas of the blood purifier 3, depending on actual needs. Test fluid flowing out of non-test areas will flow into the cover of the circular sampler and out through the connecting hole 18.

[0062] Optionally, in another embodiment of the present application, when a circular sampler is used, as shown in FIG. Figure 2 As shown, the blood deviation flow testing device of the blood purifier may further include a first conduit 9 and a container 16 .

[0063] The first end of the first conduit 9 is connected to the connecting hole 18 of the circular sampler. For some test liquids in non-test areas of the blood purifier 3, they will flow directly into the circular sampler. At this time, the first conduit 9 can be used to guide these liquids.

[0064] The container 16 is provided on the platform base 22 for receiving the test liquid flowing out of the first conduit 9. In this way, the test liquid can be directed to the container 16 for storage.

[0065] Optionally, in another embodiment of the present application, the blood deviation flow testing device of the blood purifier further includes a second catheter 10 .

[0066] The first end of the second conduit 10 is connected to the second end of the flow meter 11 , and guides the liquid flowing through each connecting pipe of the sampler to the container 16 for storage.

[0067] Optionally, in another embodiment of the present application, the blood deviation flow testing device of the blood purifier is as follows: Figure 5As shown, the test bench includes a second lifter 19. The second lifter 19 includes a rotating nut, which is mounted on the vertical rod 21. The tightness of the second lifter 19 can be adjusted by rotating the nut. When the adjustment is loose, the second lifter 19 can be moved up and down. When it needs to be fixed, the nut can be tightened.

[0068] The sampler is a square sampler, which includes a square cover 13 and multiple connecting tubes 15. Its structure is as follows: Figure 6 As shown, the multiple connecting tubes 15 can be 5-9 mm stainless steel catheters with sharp ends.

[0069] The second lifter 19 is connected to the connecting end of the square sampler and is used to control the lifting of the square sampler. When testing is required, the cover at the test liquid outlet 2 of the blood purifier 3 is removed, and the square sampler is controlled by the second lifter 19 to fit tightly with the blood purifier 3. The connecting tube 15 of the square sampler is connected to the membrane wire 17 of the blood purifier 3. When the connecting tube 15 is connected to the membrane wire 17, the end face of the stainless steel catheter 15 and the sealing glue 7 on the end face of the blood purifier 3 are tightly fitted or one end of the stainless steel catheter 15 is inserted into the sealing glue 7.

[0070] Optionally, in another embodiment of the present application, the area where the connecting tube 15 of the square sampler is set is not smaller than the test liquid outlet area of ​​the blood purifier 3, which can meet the requirements of connecting the membrane filaments in different areas of the blood purifier 3.

[0071] Optionally, in another embodiment of the present application, the blood deviation flow testing device of the blood purifier can be referred to Figure 5 , may further include a third conduit 20 and a container 16.

[0072] A first end of the third conduit 20 is connected to a second end of the flow meter 11 .

[0073] The container 16 is disposed on the platform base 22 for receiving the outflowing test liquid.

[0074] It should be noted that the first end of the third conduit 20 is connected to the second end of the flowmeter 11, and the liquid flowing through the sampler through each connecting tube 15 is directed to the container 16 for storage. At the same time, for areas where no connecting tube 15 is set, test liquid may also flow. At this time, the container 16 can also accommodate the test liquid in the area where no connecting tube 15 is set.

[0075] Optionally, in another embodiment of the present application, the blood deviation flow testing device of the blood purifier can be referred to Figure 2 and Figure 5, and may also include a chromatography data processing system (abbreviated as HLPC) 12. The chromatography data processing system 12 can fully automate the analysis process such as data acquisition, data processing, qualitative and quantitative analysis, data storage, and report output.

[0076] The chromatography data processing system is communicatively connected with the flow meter.

[0077] The chromatography data processing system is used to record the data in the flow meter and calculate the relative standard deviation of the blood purifier based on the data.

[0078] Optionally, in another embodiment of the present application, the blood deviation flow testing device of the blood purifier can be referred to Figure 2 and Figure 5 , the connecting tube and the membrane wire are connected by the sealing glue 7. When the current sampler is a circular sampler, when the cover 14 is installed on the shell of the blood purifier 3, the end face of the stainless steel tube 15 is just tightly fitted with the sealing glue 7 on the end face of the blood purifier 3 or inserted into the sealing glue 7. When the current sampler is a square sampler, the lifting device 19 is moved so that the end face of the stainless steel tube 15 of the square sampler is tightly fitted with the sealing glue 7 on the end face of the blood purifier 3 or one end of the stainless steel tube 15 in the square sampler 13 is inserted into the sealing glue 7.

[0079] In some embodiments, the process of using the blood bias flow testing device for the blood purifier to test the degree of bias flow in the blood purifier is as follows:

[0080] 1. Prepare the test solution.

[0081] 2. Connect the blood purifier to the dialysis machine according to the clearance experimental device diagram in the standard "YY 0053-2016 Hemodialysis and Related Treatment Hemodialysis Devices, Hemodiafiltration Devices, Hemofilters and Hemoconcentrators". The priming solution is normal saline solution, the priming flow rate QB is set to 100 mL / min, and the priming time is 30 minutes. The priming is to flush impurities and remove air in the blood purifier, and at the same time, to infiltrate the hollow fiber membrane in the blood purifier.

[0082] 3. After the priming is completed, remove the cover at the test fluid outlet of the blood purifier, install the blood deviation test device, set the test fluid flow rate QB to 100mL / min, circulate for 3 minutes, then set the test fluid flow rate (QB) to 200mL / min and the dialysate flow rate (QD) to 500mL / min and continue to circulate.

[0083] 4. When the cycle lasts for 10 minutes, the HPLC data processing system records the flow rate in each flow meter connected to the sampler at this moment and calculates the relative standard deviation.

[0084] 5. Determine the degree of blood deviation based on the relative standard deviation - the smaller the relative standard deviation, the smaller the degree of blood deviation, which means the more reasonable the design of the blood purifier.

[0085] When using Figure 2 When the structure is shown, the process of testing the blood purifier is as follows:

[0086] 1. Prepare the test solution, which is a 40 μmol / L VB12 aqueous solution with a protein concentration of 60 g / L ± 5 g / L and a volume of 4 L.

[0087] 2. Connect the blood purifier to the dialysis machine according to the clearance experimental protocol in the standard "YY 0053-2016 Hemodialysis and Related Treatment Hemodialysis Machines, Hemodiafilters, Hemofilters and Hemoconcentrators". Pre-flush the blood purifier with physiological saline solution (0.9% NaCl) for about 30 minutes, with a pre-flush flow rate QB of 100 mL / min.

[0088] 3. After the priming is completed, remove the cover at the outlet of the test liquid of the blood purifier, install the blood deviation test device, use a circular sampler, set the test liquid flow rate QB to 100mL / min, and circulate for 3min. The priming liquid is used for pre-filling in the front, and the test liquid circulates for 3 minutes in the back to clean out the residual saline in the blood chamber and fill the blood chamber with the test liquid. Then set the test liquid flow rate (QB) to 200mL / min and the dialysate flow rate (QD) to 500mL / min and continue to circulate;

[0089] 4. When the cycle is completed after 10 minutes, the HPLC data processing system records the flow rate in each flow meter connected to the sampler at this moment and calculates the relative standard deviation to be 1.89%;

[0090] 5. The relative standard deviation threshold of the blood purifier is set to 7%. From this, it can be judged that the degree of blood deviation in the blood purifier is small, indicating that the structural design of the blood purifier is reasonable.

[0091] When using Figure 5 The structure shown is different from the previous embodiment in that the sampler of the blood deviation flow testing device of the blood purifier is a square sampler. The other steps are the same and will not be repeated here.

[0092] The relative standard deviation calculated is 1.76%. The relative standard deviation threshold of the blood purifier is set to 7%, which shows that the blood flow deviation of the blood purifier is small, indicating that the structure design of the blood purifier is reasonable.

[0093] Each embodiment in this specification is described in a progressive manner. The same or similar parts between the embodiments can be referred to each other. Each embodiment focuses on the differences from other embodiments. In particular, for system or system embodiments, since they are basically similar to method embodiments, the description is relatively simple. For relevant parts, refer to the partial description of the method embodiment. The system and system embodiments described above are merely schematic, wherein the units described as separate components may or may not be physically separated, and the components displayed as units may or may not be physical units, that is, they may be located in one place, or they may be distributed on multiple network units. Some or all of the modules can be selected according to actual needs to achieve the purpose of the solution of this embodiment. A person of ordinary skill in the art can understand and implement it without expending creative work.

[0094] Professionals may further appreciate that the units and algorithm steps of each example described in conjunction with the embodiments disclosed herein can be implemented in electronic hardware, computer software, or a combination of the two. In order to clearly illustrate the interchangeability of hardware and software, the above description has generally described the components and steps of each example according to their functions. Whether these functions are performed in hardware or software depends on the specific application and design constraints of the technical solution. Professionals and technicians may use different methods to implement the described functions for each specific application, but such implementation should not be considered to be beyond the scope of the present invention.

[0095] The above description of the disclosed embodiments is intended to enable one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present application. Therefore, the present application is not limited to the embodiments shown herein, but is intended to encompass the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A blood flow deviation test device for a blood purifier, the blood purifier having a test liquid inlet and a test liquid outlet, the blood purifier including a plurality of membrane filaments fixed by a sealing glue, the test liquid inlet being located at a first end of the blood purifier, and the test liquid outlet being located at a second end of the blood purifier, characterized in that: The blood deviation test device includes: a test stand, a sampler and a plurality of flow meters; The test bench is used to vertically fix the blood purifier so that the second end of the blood purifier faces downward; The sampler is detachably mounted on the second end of the blood purifier, and comprises a plurality of connecting tubes, wherein the first ends of the connecting tubes are used to communicate with the membrane wire; The first end of the flow meter is connected to the second end of the connecting pipe and is used to detect the flow rate of the test liquid in the corresponding connecting pipe.

2. The device according to claim 1, characterized in that The test bench includes a vertical rod, a platform base, a first lifter and a fixing clamp; The vertical rod is installed on the platform base; The first lifter is mounted on the vertical rod; One end of the fixing clamp is connected to the first lifter, and the other end of the fixing clamp has a clamping structure, and the clamping structure is used to fix the blood purifier; The first lifter is used to control the lifting and lowering of the blood purifier.

3. The device according to claim 1, characterized in that The sampler is a circular sampler, which includes a circular cover body. The inner side of the circular cover body is provided with a thread shape that matches the thread shape of the blood purifier shell, so that when the circular sampler is set at the second end of the blood purifier, the end face of the connecting tube is tightly fitted with the end face of the blood purifier; the circular cover body is provided with a connecting hole for connecting the catheter.

4. The device according to claim 3, characterized in that Also included is a first conduit and a container; The first end of the first conduit is connected to the connecting hole of the circular sampler; The container is arranged on the platform base and is used for receiving the test liquid flowing out of the first conduit.

5. The device according to claim 4, characterized in that Also included is a second conduit; The first end of the second conduit is connected to the second end of the flow meter; The container is also used to receive the test liquid flowing out of the second catheter.

6. The device according to claim 2, characterized in that The test bench includes a second lifter; The sampler is a square sampler, and the square sampler includes a square cover; The second lifter is connected to one end of the square sampler and is used to control the lifting of the square sampler.

7. The device according to claim 1, characterized in that Also included is a third conduit and container; The first end of the third conduit is connected to the second end of the flow meter; The container is arranged on the platform base and is used for receiving the outflowing test liquid.

8. The device according to claim 1, characterized in that Also included is a chromatography data processing system; The chromatography data processing system is communicatively connected with the flow meter; The chromatography data processing system is used to record the data in the flow meter and calculate the relative standard deviation of the blood purifier based on the data.

9. The device according to claim 3, characterized in that The area where the connecting tube of the circular sampler is provided is no larger than the test liquid outlet area of ​​the blood purifier.

10. The device according to claim 6, characterized in that The area where the connecting tube of the square sampler is provided is not smaller than the test liquid outlet area of ​​the blood purifier.

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