Limiting container for ostomy mouse
By designing a restraining container to limit the activities of mice, the problems of compression of the fistula tube and inconvenience of long-term drug administration after fistula creation in mice were solved, and a safe and continuous drug administration effect was achieved.
Patent Information
- Application Number
- CN202421699475.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-17
- Publication Date
- 2025-09-23
- Estimated Expiration
- 2034-07-17
AI Technical Summary
In the prior art, the post-fistula administration method for mice easily compresses the fistula tube, is inconvenient for long-term administration, and poses the risk of tube dislodgment and bites.
A restraining container for fistula mice is designed, which includes a limiting piece and a cover. The mouse's movement is restricted by the through hole and the accommodating cavity of the limiting piece. The cover is used for sealing to fix the mouse, and medication is delivered through the through hole to avoid compression of the fistula tube.
It effectively restricts the activities of mice, avoids compression and tube dislocation of the fistula tube, improves the safety and continuity of drug administration, reduces the risk of being bitten, and is suitable for long-term drug administration.
Smart Images
Figure CN223365693U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of biological experiment tools, in particular to a confinement container for fistula mice. Background Art
[0002] Mice are important model animals in basic medical research. Many gastrointestinal studies require the creation of fistulas (e.g., duodenostomy, ileostomy, and colostomy) in mice. After the fistula is created, an external fistula tube is placed for drug delivery (often exiting subcutaneously on the back). Current drug delivery methods typically involve manually lifting and pinching the mouse, which can easily compress the fistula tube. Allowing the mouse to move freely can easily pull on the tube, causing it to become dislodged. This is also inconvenient for continuous, prolonged drug delivery. Furthermore, manual delivery carries the risk of bites. Summary of the Invention
[0003] The purpose of the utility model is to improve the problem that when administering medicine to mice with fistula tubes, the fistula tubes are easily compressed or the medicine is administered for a long time, and to provide a restraining container for fistula mice.
[0004] The technical solutions to achieve the above objectives include the following:
[0005] A restraining container for ostomy mice, comprising: a restraining member and a cover, wherein the restraining member is provided with an opening, the cover is detachably mounted on the opening of the restraining member, a receiving cavity is formed in the restraining member, and the opening is communicated with the receiving cavity;
[0006] The limiting member has at least one first through hole, which passes through the inner side of the limiting member to the outer side of the limiting member, extends along the circumference of the limiting member, and is connected to the accommodating cavity.
[0007] In one embodiment, the limiting member includes a first tube body and a second tube body, the first tube body is mounted on the second tube body, a first cavity is formed in the first tube body, a second cavity is formed in the second tube body, and the first cavity is communicated with the second cavity;
[0008] The side wall of the second tube body has at least one second through hole, and the second through hole is communicated with the second cavity.
[0009] In one embodiment, there are a plurality of first through holes, and the plurality of first through holes are arranged along the axis of the first tube body, and / or the plurality of first through holes are staggered along the axis of the first tube body;
[0010] Furthermore, the plurality of first through holes are arranged parallel to each other.
[0011] In one embodiment, there are a plurality of second through holes, and the plurality of second through holes are arranged in a matrix on the outer wall of the second tube.
[0012] In one embodiment, the first through hole is a waist-shaped hole, the width of the first through hole is 5 mm to 10 mm, and the length of the first through hole is 10 mm to 20 mm.
[0013] In one embodiment, the diameter of the second through hole is 1 mm to 3 mm.
[0014] In one embodiment, the first tube body is a columnar structure; the second tube body is a cone structure, and the largest end of the second tube body is connected to the first tube body.
[0015] In one embodiment, the outer wall of the limiting member has a third through hole, and the third through hole is extended along the length direction of the limiting member;
[0016] An extension line of the third through hole intersects with an extension line of the first through hole.
[0017] In one embodiment, there are two third through holes, and the two third through holes are arranged opposite to each other.
[0018] In one embodiment, the outer wall of the cover has a plurality of anti-slip grooves, and the anti-slip grooves extend along the height direction of the cover.
[0019] The technical solution provided by the utility model has the following advantages and effects:
[0020] The limiting container is used in ostomy drug administration. The mouse after fistula is placed into the accommodating cavity through the opening, and then the opening is sealed with a cover body, thereby confining the mouse in the accommodating cavity. This can limit the range of movement of the mouse, avoid holding the mouse for drug administration, and avoid being bitten by the mouse. In ostomy drug administration, the mouse has a pre-set ostomy tube outside the body in advance. The drug dispenser can pass through any of the first through holes and correspond to the ostomy tube, so that the ostomy tubes at multiple positions on the chest, abdomen and back of the mouse correspond to the drug dispenser, thereby realizing the drug administration operation of the ostomy tube. The ostomy tube is in the accommodating cavity to prevent the ostomy tube from being compressed. At the same time, the limiting container limits the activity of the mouse, avoids pulling the ostomy tube during drug administration, and can continuously administer drugs for a long time. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] The accompanying drawings herein illustrate specific examples of the technical solutions described in the present invention, and together with the specific implementation methods constitute a part of the specification, and are used to explain the technical solutions, principles and effects of the present invention.
[0022] Unless otherwise specified or defined, the same reference numerals in different drawings represent the same or similar technical features, and the same or similar technical features may also be represented by different reference numerals.
[0023] Figure 1 It is a schematic diagram of a limiting container in one embodiment of the present utility model;
[0024] Figure 2 This is a schematic diagram of an explosion of a restricted container in one embodiment of the present utility model;
[0025] Figure 3 This is a schematic diagram of an arrangement of multiple first through holes in one embodiment of the present invention;
[0026] Description of reference numerals:
[0027] 100. Restriction container; 1. Cover; 11. Anti-slip groove; 2. Limiting member; 21. First tube; 211. First through hole; 212. Third through hole; 213. Opening; 22. Second tube; 221. Second through hole. DETAILED DESCRIPTION
[0028] In order to facilitate the understanding of the present invention, specific embodiments of the present invention will be described in more detail below with reference to the accompanying drawings.
[0029] Unless otherwise specified or defined, the "first, second..." used in this article is only used to distinguish names and does not represent a specific quantity or order.
[0030] Unless stated otherwise or defined otherwise, the term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.
[0031] It should be noted that when an element is considered to be "fixed to" another element, it can be directly fixed to the other element or there can be an intermediate element; when an element is considered to be "connected to" another element, it can be directly connected to the other element or there can be an intermediate element; when an element is considered to be "mounted on" another element, it can be directly mounted on the other element or there can be an intermediate element. When an element is considered to be "located on" another element, it can be directly located on the other element or there can be an intermediate element.
[0032] The present invention provides a confinement container 100 for a fistula mouse. Figures 1 to 2As shown, the container 100 includes a retaining member 2 and a cover 1. The retaining member 2 is provided with an opening 213. The cover 1 is detachably mounted on the opening 213 of the retaining member 2. A receiving cavity is formed in the retaining member 2, and the opening 213 is connected to the receiving cavity. The retaining member 2 has six first through holes 211. The first through holes 211 extend from the inner side of the retaining member 2 to the outer side of the retaining member 2. The first through holes 211 extend along the circumference of the retaining member 2 and are connected to the receiving cavity. Specifically, the restricting container 100 is used for drug administration during fistula formation. A mouse after fistula formation is placed into the receiving cavity through the opening 213. The opening 213 is then sealed with the cover 1, thereby confining the mouse in the receiving cavity. This can limit the mouse's range of movement, avoid holding the mouse during drug administration, and prevent the mouse from being bitten. For drug delivery via fistula, a fistula tube is pre-installed outside the mouse. A drug delivery device can be inserted through any of the first through-holes 211 and aligned with the fistula tube, allowing for drug delivery to be performed on fistula tubes located at various locations on the mouse's chest, abdomen, or back. The fistula tube is contained within the cavity, preventing compression. The restraining container 100 also restricts the mouse's movement, preventing the tube from being pulled during drug delivery, allowing for continuous drug delivery over an extended period.
[0033] In some embodiments, as Figure 1 As shown, the limiting member 2 includes a first tube body 21 and a second tube body 22. The first tube body 21 is installed on the second tube body 22. A first cavity is formed in the first tube body 21, and a second cavity is formed in the second tube body 22. The first cavity is connected to the second cavity. The side wall of the second tube body 22 has at least one second through hole 221, and the second through hole 221 is connected to the second cavity. Specifically, the mouse enters the first tube body 21 through the opening 213, and the mouse can move into the second tube body 22, so that the mouse has a certain amount of space to move in the accommodating cavity. Since the mouse needs to be administered in the limiting container 100 for a long time; when the mouse is placed, the mouse's head is facing the second tube body 22, and the second through hole 221 is used to allow air to circulate inside and outside the second tube body 22. The mouse can breathe through the second through hole 221, so that the mouse can keep breathing smoothly during the administration process.
[0034] Preferably, Figure 1 As shown, there are six first through holes 211, arranged along the axis of the first tube 21; and the six first through holes 211 are arranged parallel to each other. Specifically, the six first through holes 211 form a set of drug delivery channels, with two groups of drug delivery channels arranged opposite each other. By arranging the first through holes 211 in parallel, multiple first through holes 211 are distributed along the sidewall of the first tube 21, so that the chest, abdomen, or back of the mouse can correspond to any of the first through holes 211. Furthermore, the circumference of the first through holes 211 can account for 30% to 40% of the circumference of the first tube 21.
[0035] Preferably, Figure 3 As shown, the six first through holes 211 can also be staggered in the axial direction of the first tube body 21, and the drug administration channel surrounds the first tube body 21 without dead angles. By staggering multiple first through holes 211, the fistula tube on the chest, abdomen and back of the mouse can be observed, thereby improving drug administration efficiency.
[0036] Preferably, there are multiple second through holes 221, which are arranged in a matrix on the outer wall of the second tube 22. Specifically, the multiple second through holes 221 can improve the air circulation efficiency inside and outside the second tube 22, further improving the smoothness of the mouse's breathing in the second tube 22.
[0037] Preferably, the first through hole 211 is a waist-shaped hole, with a width of 5mm to 10mm and a length of 10mm to 20mm. In this embodiment, the width of the first through hole 211 refers to the distance in the direction of the axis of the first tube 21, and the length of the first through hole 211 refers to the distance in the circumferential direction of the first tube 21. The diameter of the second through hole 221 is 1mm to 3mm. Specifically, the width of the first through hole 211 is 9mm, which facilitates the passage of the injection tube of the applicator while also preventing mice from passing through the first through hole 211, thus accommodating mice of most sizes. The diameter of the second through hole 221 is 2mm, which facilitates the passage of gas.
[0038] In some embodiments, as Figure 1 As shown, the first tube 21 has a columnar structure; the second tube 22 has a conical structure, with the largest end of the second tube 22 connected to the first tube 21. Specifically, the outer wall of the first tube 21 has external threads, and the inner wall of the cover 1 has internal threads. The cover 1 is threadedly connected to the opening 213 of the first tube 21, facilitating the installation and removal of the confinement container 100. The second tube 22 is configured as a conical structure to reduce the space for the mouse's head to move. When the mouse's head enters the second tube 22, the mouse cannot turn around in the second tube 22. This further limits the mouse's range of movement within the confinement container 100 and prevents the mouse from moving up and down in the confinement container 100.
[0039] In some embodiments, as Figure 1 As shown, the outer wall of the retaining member 2 has a third through hole 212 extending along the length of the retaining member 2; the extension line of the third through hole 212 intersects the extension line of the first through hole 211. Specifically, the third through hole 212 is provided to allow the mouse's tail to be exposed. During drug administration to the mouse, if the mouse's fistula tube cannot be administered through the first through hole 211, the mouse's tail can be picked up near the third through hole 212 and the mouse's posture can be adjusted so that the mouse's fistula tube corresponds to the first through hole 211, further facilitating drug administration through the mouse's fistula tube.
[0040] In addition, the first through hole 211, the second through hole 221, and the third through hole 212 are all hollow holes, and external light can be projected into the accommodating cavity, avoiding causing a feeling of oppression to the mouse and allowing the mouse to maintain a relatively stable state during the drug administration process.
[0041] Preferably, Figure 1 and Figure 2 As shown, there are two third through holes 212, which are arranged opposite to each other. Specifically, by providing two third through holes 212, the tail of the mouse can be more easily extended outside the confinement container 100, which facilitates adjusting the position of the mouse in the accommodating cavity.
[0042] Preferably, Figure 1 As shown, the outer wall of the cover 1 has a plurality of anti-skid lines 11, which extend along the height direction of the cover 1. Specifically, the anti-skid lines 11 are used to increase the friction resistance between the fingers and the cover 1, making it easier to screw in or out of the cover 1.
[0043] It should be noted that the restraining container 100 is used to administer medication to mice during fistula experiments. Once the mouse enters the restraining container 100, it restricts its range of movement within the containment chamber and allows medication delivery from the outside through the first through-hole 211. In other embodiments, the mouse can be restrained in other containers, and medication can be delivered from the outside through the through-hole. This is not particularly limiting.
[0044] When quoting drawing descriptions, new features that appear are described; in order to avoid repeated quoting of drawings which would result in a less concise description, features that have been described clearly will not be quoted from the drawings one by one.
[0045] The purpose of the above embodiments is to exemplify and deduce the technical solution of the utility model, and to fully describe the technical solution, purpose and effect of the utility model. Its purpose is to enable the public to have a more thorough and comprehensive understanding of the disclosed content of the utility model, and it does not limit the scope of protection of the utility model.
[0046] The above embodiments are not exhaustive of the present invention, and there may be many other embodiments not listed. Any replacements and improvements made without violating the concept of the present invention are within the scope of protection of the present invention.
Claims
1. A restraining container for ostomy mice, characterized in that: include: A limiting member and a cover body, wherein the limiting member is provided with an opening, the cover body is detachably mounted on the opening of the limiting member, an accommodating cavity is formed in the limiting member, and the opening is communicated with the accommodating cavity; The limiting member has at least one first through hole, the first through hole extending from the inner side of the limiting member to the outer side of the limiting member, the first through hole extending along the circumference of the limiting member, and the first through hole communicating with the accommodating cavity; The limiting member includes a first tube body and a second tube body, the first tube body is mounted on the second tube body, a first cavity is formed in the first tube body, a second cavity is formed in the second tube body, and the first cavity is communicated with the second cavity; The side wall of the second tube body has at least one second through hole, and the second through hole is connected to the second cavity; There are a plurality of the first through holes, and the plurality of first through holes are arranged along the axis direction of the first tube body, and / or; The plurality of first through holes are staggeredly arranged along the axis direction of the first tube body; Furthermore, the plurality of first through holes are arranged parallel to each other.
2. The restraining container for ostomy mice according to claim 1, wherein: There are a plurality of second through holes, and the plurality of second through holes are arranged in a matrix on the outer wall of the second tube body.
3. The restraining container for ostomy mice according to claim 1, wherein: The first through hole is a waist-shaped hole, the width of the first through hole is 5 mm to 10 mm, and the length of the first through hole is 10 mm to 20 mm.
4. The restraining container for ostomy mice according to claim 1, wherein The diameter of the second through hole is 1 mm to 3 mm.
5. The restraining container for ostomy mice according to claim 1, wherein The first tube body has a columnar structure; the second tube body has a cone-shaped structure, and the largest end of the second tube body is connected to the first tube body.
6. The restraining container for ostomy mice according to any one of claims 1 to 5, characterized in that: The outer wall of the limiting member has a third through hole, and the third through hole is extended along the length direction of the limiting member; An extension line of the third through hole intersects with an extension line of the first through hole.
7. The restraining container for ostomy mice according to claim 6, wherein: There are two third through holes, and the two third through holes are arranged opposite to each other.
8. The restraining container for ostomy mice according to any one of claims 1 to 5, characterized in that: The outer wall of the cover body has a plurality of anti-slip grooves, and the anti-slip grooves are extended along the height direction of the cover body.