Mixing device for nucleic acid drug component detection

By designing a clamping assembly and a rotary drive assembly driven by an electric push rod and a servo motor, the problem of cumbersome replacement of clamping assemblies in the existing technology is solved, rapid clamping and mixing of test tubes is achieved, and the efficiency of nucleic acid drug testing is improved.

CN223381482UActive Publication Date: 2025-09-26SHANGHAI ORIENT BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422840821.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-21
Publication Date
2025-09-26
Estimated Expiration
2034-11-21

AI Technical Summary

Technical Problem

In the existing nucleic acid drug testing process, the clamping components of the mixing device are cumbersome to replace, which affects the experimental efficiency.

Method used

A mixing device including a placement rack, a clamping assembly and a rotation drive assembly was designed. It was driven by an electric push rod and a servo motor to achieve rapid clamping and shaking mixing of test tubes.

Benefits of technology

It improves the convenience of test tube clamping and mixing efficiency, saves time and improves experimental efficiency.

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Abstract

The utility model discloses a mixing device for nucleic acid medicine component detection, which relates to the field of medicine mixing and comprises a placing frame, a notch is arranged on a top plate where the placing frame is located, a placing groove is arranged on a bottom plate where the placing frame is located, the placing frame is mounted in a mounting frame, the placing frame is rotatably arranged on the mounting frame through a rotating shaft, and the rotating shaft is arranged in the placing groove. A rotary driving assembly for driving the rotating shaft to rotate is arranged on one side of the mounting frame, and a clamping assembly for fixing the test tube is arranged on the mounting frame. The clamping assemblies are arranged to clamp a test tube filled with nucleic acid medicine, the electric push rod drives the second fixing block to move backwards, the arc-shaped clamps hinged to the hinge rods clamp the test tube, the multiple arc-shaped clamps are connected through the connecting rods, the clamping assemblies in the same row can be controlled at the same time, and the operation is convenient. By arranging the rotary driving assembly, the placement rack can be conveniently driven to shake back and forth, so that nucleic acid drugs in the test tubes are fully mixed.
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Description

Technical Field

[0001] The utility model relates to the field of drug mixing, in particular to a mixing device for detecting nucleic acid drug components. Background Art

[0002] Nucleic acid drugs, also known as nucleotide drugs, include oligoribonucleotides (RNA) or oligodeoxyribonucleotides (DNA) with different functions, which mainly act at the genetic level. These drugs can be made from nucleic acids (including nucleotides and deoxynucleotides) extracted from animal or microbial cells, or prepared through artificial synthesis. They are substances with nucleic acid structure and pharmacological effects.

[0003] In the process of nucleic acid drug testing, sample mixing is a key step. In the existing technology, most mixing is usually done by clamping the test tube through a clamping assembly. After fixing it, the eccentric wheel is driven by a motor to rotate, causing it to swing up and down under the action of a spring to mix.

[0004] When using a mixing device, it is often necessary to shake multiple groups of test tubes at the same time. The existing clamping components are usually fixed by bolts, and they need to be removed and replaced one by one when replacing reagents. However, the disassembly and assembly process is cumbersome and difficult to operate smoothly, affecting experimental efficiency. Utility Model Content

[0005] Based on this, the purpose of the present invention is to provide a mixing device for detecting nucleic acid drug components to solve the technical problems mentioned in the above background technology.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a mixing device for detecting nucleic acid drug components, comprising a placing rack, a top plate where the placing rack is located is provided with a slot communicating with the interior, a bottom plate where the placing rack is located is provided with a placing slot, the placing rack is installed in the mounting rack, and the placing rack is rotatably arranged on the mounting rack through a rotating shaft, a rotating drive component that drives the rotating shaft to rotate is provided on one side of the mounting rack, and a clamping component for fixing the test tube is provided on the mounting rack, the clamping component comprises a plurality of groups of slide grooves provided on the top plate of the mounting rack, a slider is provided for sliding in the slide groove, an arc clamp is provided at the end of the slider, and every two arc clamps form a group, a fixing block is provided on the outer wall of the arc clamp, and the plurality of arc clamps are connected by a connecting rod, a first fixing plate is provided on one side of the mounting rack, and a driving mechanism that drives each group of arc clamps to move relative to each other is installed on the first fixing plate.

[0007] By adopting the above technical solution, when mixing is required, the test tube containing the nucleic acid drug is first inserted into the placement slot along the slot, and the arc clamp is driven by the driving mechanism to clamp the test tube. After clamping is completed, the rotating shaft is driven to rotate by the rotating drive assembly, so that the placement rack swings left and right in the mounting rack to fully mix the nucleic acid drug in the test tube.

[0008] The utility model is further configured such that the driving mechanism includes a hinged rod rotatably arranged on one group of fixed blocks, the hinged rod is rotatably connected to a second fixed block at one end away from the fixed block, and the end of the second fixed block is connected to a linear drive device.

[0009] As a preferred embodiment, it is convenient to clamp the test tube, which saves time and improves efficiency.

[0010] The present invention is further configured such that the linear drive device includes an electric push rod, and the electric push rod is fixedly arranged on the first fixed plate.

[0011] Preferably, it is convenient to push the second fixing block to move back and forth, thereby controlling the clamping assembly to clamp.

[0012] The utility model is further configured such that a protective pad is provided on the inner wall of the arc-shaped clamp, and the protective pad is made of rubber.

[0013] As a preferred embodiment, it is convenient to increase the friction force and protect the test tube at the same time.

[0014] The utility model is further configured such that the rotation drive assembly includes a mounting frame mounted on one side of the mounting frame, a first mounting slot being provided on the mounting frame, a threaded rod being installed in the first mounting slot, one end of the threaded rod being connected to the output end of the servo motor, a driving block being threadedly sleeved on the outer surface of the threaded rod, a rack being provided on the top of the driving block, a gear being meshed with the rack being provided above the rack, and the gear being sleeved on the rotating shaft.

[0015] Preferably, the placement rack is driven to rock back and forth to mix the test tubes.

[0016] The present invention is further configured such that a second mounting groove is provided on the mounting frame, and the second mounting groove is used for mounting the servo motor.

[0017] As a preferred embodiment, it is convenient to install the servo motor, so that the servo motor is more stable during operation.

[0018] The present invention is further configured such that a soft pad is provided in the placement groove, and the soft pad is made of rubber.

[0019] As a preferred embodiment, it is convenient to protect the bottom of the test tube. Rubber has good elasticity and protective properties, which can better protect the test tube.

[0020] In summary, the present invention has the following beneficial effects:

[0021] 1. The utility model achieves the purpose of clamping a test tube containing a nucleic acid drug by setting a clamping assembly. The second fixed block is driven to move forward and backward by the electric push rod. When the electric push rod drives the second fixed block to move forward, the two arc-shaped clamps hinged to the hinged rod move to both sides and open. After the test tube is placed in, the second fixed block is driven to move backward by the electric push rod to clamp the test tube. Multiple arc-shaped clamps are connected by connecting rods. By driving one group of arc-shaped clamps, it is convenient to simultaneously operate the same row of clamping assemblies. This method saves time and improves efficiency.

[0022] 2. The utility model is convenient for driving the placement rack to rock back and forth by setting a rotary drive assembly, starting the servo motor to drive the threaded rod to rotate, thereby driving the driving block to move back and forth, causing the rack set on the upper end of the driving block to move back and forth, causing the gear meshing with the rack to rotate, driving the rotating shaft to rotate, thereby driving the placement rack to rock back and forth to mix the test tubes. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0024] Figure 2 This is a schematic diagram of the structure of the clamping assembly of the present utility model;

[0025] Figure 3 This is a schematic diagram of the structure of the rotary drive assembly of the utility model;

[0026] Figure 4 This is a schematic diagram of the driving mechanism structure of the utility model.

[0027] Description of reference numerals:

[0028] 100. Placement rack; 101. Mounting rack; 102. Rotating shaft; 103. Notch; 104. Placement slot; 200. Mounting frame; 201. First mounting slot; 202. Second mounting slot; 203. Threaded rod; 204. Drive block; 205. Servo motor; 206. Rack; 207. Gear; 300. Slide; 301. Slider; 302. Arc clamp; 303. Protective pad; 304. Fixed block; 400. First fixed plate; 401. Electric push rod; 402. Second fixed block; 403. Articulated rod; 404. Connecting rod. DETAILED DESCRIPTION

[0029] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. The embodiments described below with reference to the drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0030] The following describes an embodiment of the present invention based on its overall structure.

[0031] See also Figure 1-Figure 4 , including a placement rack 100, a notch 103 communicating with the interior is provided on the top plate where the placement rack 100 is located, a placement slot 104 is provided on the bottom plate where the placement rack 100 is located, and the placement rack 100 is installed in the mounting rack 101. When mixing is required, the test tube containing the nucleic acid drug is first inserted into the placement slot 104 along the notch 103, and the placement rack 100 is rotated on the mounting rack 101 through the rotating shaft 102. A rotating drive component that drives the rotating shaft 102 to rotate is provided on one side of the mounting rack 101. A clamping component for fixing the test tube is provided on the mounting rack 101, and the clamping component includes a plurality of slide grooves 300 provided on the top plate of the mounting rack 101. The slide grooves 300 A slider 301 is provided for internal sliding, and an arc-shaped clamp 302 is provided at the end of the slider 301, and every two arc-shaped clamps 302 form a group. A fixed block 304 is provided on the outer wall of the arc-shaped clamp 302, and multiple arc-shaped clamps 302 are connected by connecting rods 404. A first fixed plate 400 is provided on one side of the mounting frame 101, and a driving mechanism for driving each group of arc-shaped clamps 302 to move relative to each other is installed on the first fixed plate 400. The second fixed block 402 is driven to move backward by the electric push rod 401 to clamp the test tube. After clamping is completed, the rotating shaft 102 is driven to rotate by the rotating drive assembly, so that the placement rack 100 swings left and right in the mounting rack 101 to fully mix the nucleic acid drugs in the test tube.

[0032] In the above embodiment, please refer to Figure 4 The driving mechanism includes a hinged rod 403 rotatably arranged on one set of fixed blocks 304, and the hinged rod 403 is rotatably connected to a second fixed block 402 at one end away from the fixed block 304, and the end of the second fixed block 402 is connected to a linear drive device.

[0033] The second fixed block 402 is driven to move forward and backward by a linear drive device. When the linear drive device drives the second fixed block 402 to move forward, the two arc clamps 302 hinged to the hinge rod 403 move to both sides and open. The multiple arc clamps 302 are connected by a connecting rod 404. By driving one group of arc clamps 302, it is convenient to simultaneously operate the same row of clamping components. After the test tube is placed in, the second fixed block 402 is driven backward by the linear drive device to clamp the test tube. This method saves time and improves efficiency.

[0034] In the above embodiment, please refer to Figure 4 The linear drive device includes an electric push rod 401, and the electric push rod 401 is fixedly set on the first fixed plate 400.

[0035] The electric push rod 401 is provided to facilitate pushing the second fixing block 402 to move back and forth, thereby controlling the clamping assembly to clamp.

[0036] In the above embodiment, please refer to Figure 4 A protective pad 303 is provided on the inner wall of the arc-shaped clamp 302, and the protective pad 303 is made of rubber.

[0037] The protection pad 303 is provided to increase friction. The rubber material has greater friction and a certain elasticity, and can protect the test tube.

[0038] In the above embodiment, please refer to Figure 3 The rotation drive assembly includes a mounting frame 200 mounted on one side of the mounting frame 101, and a first mounting slot 201 is opened on the mounting frame 200. A threaded rod 203 is installed in the first mounting slot 201, and one end of the threaded rod 203 is connected to the output end of the servo motor 205. A driving block 204 is threadedly sleeved on the outer surface of the threaded rod 203, and a rack 206 is provided at the top of the driving block 204. A gear 207 meshing with the rack 206 is provided above the rack 206, and the gear 207 is sleeved on the rotating shaft 102.

[0039] The servo motor 205 is started to drive the threaded rod 203 to rotate, thereby driving the driving block 204 to move back and forth, causing the rack 206 set on the upper end of the driving block 204 to move back and forth, causing the gear 207 meshing with the rack 206 to rotate, driving the rotating shaft 102 to rotate, thereby driving the placement rack 100 to rock back and forth to mix the test tubes.

[0040] In the above embodiment, please refer to Figure 1 The installation frame 200 is provided with a second installation slot 202 , and the second installation slot 202 is used for installing the servo motor 205 .

[0041] The second installation slot 202 is provided to facilitate installation of the servo motor 205 , so that the servo motor 205 is more stable during operation.

[0042] In the above embodiment, please refer to Figure 1 A soft pad is provided in the placement groove 104, and the soft pad is made of rubber.

[0043] The bottom of the test tube can be protected by providing a soft pad. The rubber has good elasticity and protective properties, and can better protect the test tube.

[0044] During the specific operation of the present invention: when mixing is required, the test tube containing the nucleic acid drug is first inserted into the placement groove 104 along the slot 103, and the second fixed block 402 is driven to move back and forth by the electric push rod 401. When the electric push rod 401 drives the second fixed block 402 to move forward, the two arc clamps 302 hinged to the hinge rod 403 move to both sides and open. The multiple arc clamps 302 are connected by a connecting rod 404. By driving one group of arc clamps 302, it is convenient to simultaneously operate the same row of clamping components. After the test tube is placed, the second fixed block 402 is driven backward by the electric push rod 401 to clamp the test tube. After clamping is completed, the rotating shaft 102 is driven to rotate by the rotating drive component, so that the placement rack 100 swings left and right in the mounting rack 101, thereby fully mixing the nucleic acid drug in the test tube.

[0045] Although embodiments of the present invention have been shown and described, these specific embodiments are merely explanations of the present invention and are not limitations on the present invention. The specific features, structures, materials, or characteristics described may be combined in a suitable manner in any one or more embodiments or examples. After reading this specification, those skilled in the art may make modifications, substitutions, and variations to the embodiments as needed without departing from the principles and purpose of the present invention, but as long as they are within the scope of the claims of the present invention, they are protected by patent law.

Claims

1. A mixing device for detecting nucleic acid drug components, comprising a placement rack (100), a top plate on which the placement rack (100) is located having a notch (103) communicating with the interior, and a bottom plate on which the placement rack (100) is located having a placement groove (104), characterized in that: The placing rack (100) is installed in the mounting rack (101), and the placing rack (100) is rotatably arranged on the mounting rack (101) via a rotating shaft (102). A rotating drive assembly for driving the rotating shaft (102) to rotate is provided on one side of the mounting rack (101). A clamping assembly for fixing the test tube is provided on the mounting rack (101). The clamping assembly includes a plurality of groups of slide grooves (300) provided on the top plate of the mounting rack (101). The slide grooves (300) slide into the test tubes. A slider (301) is provided, an arc-shaped clamp (302) is provided at the end of the slider (301), and each two arc-shaped clamps (302) form a group. A fixing block (304) is provided on the outer wall of the arc-shaped clamp (302), and a plurality of the arc-shaped clamps (302) are connected by a connecting rod (404). A first fixing plate (400) is provided on one side of the mounting frame (101), and a driving mechanism for driving each group of arc-shaped clamps (302) to move relative to each other is installed on the first fixing plate (400).

2. A mixing device for detecting nucleic acid drug components according to claim 1, characterized in that: The driving mechanism comprises a hinged rod (403) rotatably arranged on one of the fixed blocks (304); one end of the hinged rod (403) away from the fixed block (304) is rotatably connected to a second fixed block (402); and the end of the second fixed block (402) is connected to a linear driving device.

3. A mixing device for detecting nucleic acid drug components according to claim 2, characterized in that: The linear drive device comprises an electric push rod (401), and the electric push rod (401) is fixedly arranged on the first fixed plate (400).

4. A mixing device for detecting nucleic acid drug components according to claim 1, characterized in that: A protective pad (303) is provided on the inner wall of the arc-shaped clamp (302), and the protective pad (303) is made of rubber.

5. A mixing device for detecting nucleic acid drug components according to claim 1, characterized in that: The rotary drive assembly comprises a mounting frame (200) mounted on one side of a mounting frame (101), a first mounting slot (201) being provided on the mounting frame (200), a threaded rod (203) being installed in the first mounting slot (201), one end of the threaded rod (203) being connected to the output end of a servo motor (205), a driving block (204) being threadedly sleeved on the outer surface of the threaded rod (203), a rack (206) being provided at the top end of the driving block (204), a gear (207) being meshed with the rack (206) being provided above the rack (206), and the gear (207) being sleeved on the rotating shaft (102).

6. A mixing device for detecting nucleic acid drug components according to claim 5, characterized in that: The installation frame (200) is provided with a second installation slot (202), and the second installation slot (202) is used for installing a servo motor (205).

7. A mixing device for detecting nucleic acid drug components according to claim 1, characterized in that: A soft pad is provided in the placement groove (104), and the soft pad is made of rubber.