Tool for preventing sample adding dislocation
By designing a tool to prevent sample dislocation, and using infrared sensors and positioning markers, the problem of position dislocation during sample loading in 96-well deep-well plates is solved, achieving efficient and accurate sample loading operations.
Patent Information
- Application Number
- CN202422508099.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-16
- Publication Date
- 2025-09-30
- Estimated Expiration
- 2034-10-16
AI Technical Summary
In medical molecular laboratories, sample position misalignment is prone to occur during the loading process of 96-well deep-well plates, resulting in slow loading speed, low efficiency and increased experiment time.
A tool to prevent sample misplacement has been designed, which includes a placement box, a U-shaped bar, a movable push piece and an infrared sensor. The infrared sensor monitors the sample loading progress and lights up the corresponding positioning mark to ensure accurate sample positioning.
Effectively avoid sample loading errors, improve loading efficiency, ensure loading quality, and reduce human errors through automated monitoring.
Smart Images
Figure CN223393459U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the field of medical supplies, and in particular relates to a tool for preventing sample addition dislocation. Background Art
[0002] The 96-well plate is a commonly used tool for pre-processing clinical biological samples. It is mainly used for high-throughput processing of samples. Whether it is protein precipitation, liquid-liquid extraction, or solid-phase extraction, it can be achieved using a 96-well plate.
[0003] In medical molecular laboratory testing, samples need to be added to a 96-well deep-well plate for subsequent automatic testing equipment. Due to the small size of the 96-well deep-well plate, it is impossible to number each sample on the deep-well plate. However, each original sample needs to be transferred from the original tube to the 96-well deep-well plate in a predetermined order to ensure that the sample number finally taken out of the equipment corresponds to the original number. In this process, it is necessary to accurately transfer the 96 samples into each deep well without misalignment, so the testing staff needs to be highly focused and remember the specific location of the deep well each time.
[0004] At present, the process of adding samples mainly relies on manual memory of the sample adding position, which can easily lead to the misplaced sample addition. Since sample addition requires manual memory, it is easy to forget if one is not careful. Recounting the position will increase the experimental time and slow down the sample addition speed. Summary of the Invention
[0005] The purpose of the utility model is to provide a tool for preventing sample misplacement which can effectively avoid the occurrence of sample misplacement, ensure quality and improve efficiency.
[0006] The technical solution is as follows:
[0007] A tool for preventing sample dislocation includes a placement box, a U-shaped bar is fixedly connected to the top of the placement box, a first groove track is opened on the inner side of the U-shaped bar, a movable push piece is slidably connected to the inside of the first groove track, a second groove track is opened on the right side of the placement box, a baffle is slidably connected to the inside of the second groove track, an installation cavity is opened on the bottom surface of the placement box, a clamping assembly is arranged on the right side of the installation cavity inside the placement box, a row positioning mark is arranged on the first side of the upper surface of the U-shaped bar, and a column positioning mark is arranged on the second side of the upper surface of the U-shaped bar, an infrared sensor is arranged on the left end of the movable push piece, and a microcontroller electrically connected to the row positioning mark and the infrared sensor is arranged in the placement box.
[0008] In one embodiment, the clamping assembly includes an abutment plate and a clamping plate, both of which are arranged inside the placement box, and at least four telescopic springs are fixedly connected between the abutment plate and the clamping plate, and the outer side of the abutment plate abuts against the inner side of the baffle.
[0009] In one embodiment, a clamping block is fixedly connected to the right side of the first groove track, and a limiting strip is fixedly connected to the left end of the movable push piece and the first groove track.
[0010] In one embodiment, four small electric push rods are fixedly installed on the bottom surface of the installation cavity, and the output ends of the four small electric push rods are fixedly connected to push plates.
[0011] In one embodiment, a battery compartment is provided on the bottom surface of the placement box and the left side of the installation cavity, and a cover is fixedly connected to the top of the battery compartment by screws.
[0012] In one embodiment, a charging interface for charging is provided at a position on the front side of the placement box corresponding to the battery compartment.
[0013] In one embodiment, an LED light button is fixedly installed on the left front end of the placement box, and a timer button is fixedly installed on the right front end of the placement box.
[0014] In one embodiment, a timer display screen is fixedly installed in the middle of the front side of the placement box.
[0015] In one embodiment, the microcontroller is fixedly mounted in the middle of the bottom surface of the mounting cavity.
[0016] In one embodiment, at least all of the row positioning marks and the column positioning marks are internally installed with LED lamp beads.
[0017] The technical solution provided by the utility model has the following advantages and effects:
[0018] 1. The pusher moves one column at a time, and then the infrared sensor lights up the row in the current column where the sample has been added, so that the inspection operator knows where to add the next sample. This can effectively avoid the situation where the sample is added to the wrong position, ensure quality and improve efficiency.
[0019] 2. By using a tool to prevent sample dislocation, the push piece can be moved to cover the holes that have not yet been loaded with samples, which can effectively avoid contamination. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 This is a schematic structural diagram of an embodiment of the present utility model;
[0021] Figure 2 This is an exploded view of the placement box and baffle in an embodiment of the present utility model;
[0022] Figure 3 This is a schematic diagram of the internal structure of the placement box in an embodiment of the present utility model;
[0023] Figure 4 This is a cross-sectional view of a placement box in an embodiment of the present utility model;
[0024] Figure 5 An exploded view of the U-shaped bar and the movable push piece in the embodiment of the present utility model;
[0025] Figure 6 It is a compression assembly in an embodiment of the present utility model.
[0026] Description of reference numerals:
[0027] 1. Placement box; 2. U-shaped bar; 3. First groove track; 4. Card block; 5. Moving push piece; 6. Limiting bar; 7. Row positioning mark; 8. Column positioning mark; 9. Mounting cavity; 10. Small electric push rod; 11. Push plate; 12. Battery compartment; 13. Clamping assembly; 1301. Abutment plate; 1302. Clamping plate; 1303. Telescopic spring; 14. Second groove track; 15. Baffle; 16. LED light button; 17. Timer display; 18. Timer button; 19. Charging port; 20. Microcontroller. DETAILED DESCRIPTION
[0028] In order to facilitate the understanding of the present invention, specific embodiments of the present invention will be described in more detail below with reference to the accompanying drawings.
[0029] Unless otherwise specified or defined, the "first, second..." used in this article is only used to distinguish names and does not represent a specific quantity or order.
[0030] Unless stated otherwise or defined otherwise, the term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.
[0031] It should be noted that, in this document, “fixed to” or “connected to” may mean directly fixing or connecting to an element, or indirectly fixing or connecting to an element.
[0032] like Figure 1 、 Figure 2 and Figure 3The tool for preventing sample dislocation shown in the figure comprises a placement box 1, a U-shaped bar 2 is fixedly connected to the top of the placement box 1, a first groove track 3 is provided inside the U-shaped bar 2, a mobile push piece 5 is slidably connected to the first groove track 3, and an infrared sensor (not shown in the figure) is installed on the mobile push piece 5 corresponding to the position of each row, which can sense the row currently being sampled. The first groove track 3 ensures the stable sliding of the mobile push piece 5, and the infrared sensor on the mobile push piece 5 can monitor the sample loading progress in real time, thereby improving the degree of automation of the operation. A second groove track 14 is provided on the right side of the placement box 1, and a baffle 15 is slidably connected to the inside of the second groove track 14. The bottom surface of the placement box 1 is provided with a mounting cavity 9, and four small electric push rods 10 are fixedly installed on the bottom surface of the mounting cavity 9. The output ends of the four small electric push rods 10 are fixedly connected to a push plate 11. The small electric push rods 10 provide a stable and controllable thrust, so that the 96-hole deep well plate can be smoothly pushed out after the sample loading is completed, thereby improving the convenience and efficiency of the operation. A clamping assembly 13 is provided on the inside of the placement box 1 and on the right side of the mounting cavity 9.
[0033] Please refer to Figure 6 As shown, the clamping assembly 13 includes an abutment plate 1301 and a clamping plate 1302, and the abutment plate 1301 and the clamping plate 1302 are both arranged inside the placement box 1, and at least four telescopic springs 1303 are fixedly connected between the abutment plate 1301 and the clamping plate 1302. The outer side of the abutment plate 1301 abuts against the inner side of the baffle 15. The clamping assembly 13 can be adaptively adjusted according to the size and shape of the deep well plate through the design of the telescopic spring 1303, thereby ensuring the stability of the deep well plate during the sample addition process and preventing sample overflow or dislocation.
[0034] Please refer to Figure 5 As shown, a clamping block 4 is fixedly connected to the right side of the first groove track 3 , and a limiting strip 6 is fixedly connected to the left end of the movable push piece 5 and the inside of the first groove track 3 .
[0035] Please refer to Figure 5 As shown, eight row positioning marks 7 are set on the left side of the upper surface of the U-shaped bar 2, and twelve column positioning marks 8 are set on the front or back side of the upper surface of the U-shaped bar 2. The eight row positioning marks 7 are marked with numbers 1-8 respectively, and the twelve column positioning marks 8 are marked with numbers 1-12 respectively.
[0036] In some examples, an infrared sensor covering all row positioning marks 7 may be installed on the movable push plate 5, and the row where the well currently being loaded is located is determined in the controller based on the infrared data.
[0037] Please refer to Figure 4 As shown, a battery compartment 12 is provided on the bottom surface of the placement box 1 and the left side of the installation cavity 9, and a cover is fixedly connected to the top of the battery compartment 12 by screws.
[0038] Please refer to Figure 1 As shown, a charging interface 19 for charging is provided at the front side of the placement box 1 corresponding to the battery compartment 12. The design of the battery compartment 12 enables the entire tool to operate independently of an external power supply, and the charging interface 19 provides a convenient charging method to ensure the continuous use of the tool.
[0039] Please refer to Figure 1 As shown, an LED light button 16 is fixedly installed on the left front end of the placement box 1, and a timer button 18 is fixedly installed on the right front end of the placement box 1.
[0040] Please refer to Figure 1 As shown, a timer display screen 17 is fixedly installed in the middle of the front side of the placement box 1, and the timer button 18 and the timer display screen 17 provide the user with real-time sample addition time information, which helps to monitor the operation efficiency and accuracy.
[0041] Please refer to Figure 4 As shown, a microcontroller 20 is fixedly installed in the middle of the bottom surface of the installation cavity 9. The microcontroller 20 serves as the control core of the entire tool, and can receive and process signals from various sensors and respond according to preset programs.
[0042] Please refer to Figure 5 As shown, both the row positioning mark 7 and the column positioning mark 8 are internally installed with LED lamp beads. The LED lamp beads light up and go out. The row positioning mark 7 can light up the row positioning mark 7 of the corresponding row according to the number of rows of the triggered infrared sensors. For example, if the wells in the third row are currently being loaded, when the loading head gradually extends into the wells in the third row from above, the infrared sensors in the third row on the movable push piece 5 are triggered accordingly, sending a corresponding electrical signal to the controller, which then lights up the row positioning mark 7 in the third row. The lighting of the column positioning mark 8 can be lit according to the maximum number of triggering times of the row positioning mark 7 recorded in the controller. For example, if the maximum number of triggering times of all row positioning marks 7 is 3, the column positioning mark 8 in the third column will be lit. This allows the inspection operator to know where to add the next sample, ensuring that the loading is correct. It is easy to understand that the row positioning mark 7 needs to be installed with an LED lamp bead, while the column positioning mark 8 can only display the text 1-12 and can have no LED lamp bead, because the current column of sample addition can be determined by moving the push piece 5 to the right and the text on the column positioning mark 8.
[0043] Working principle: When using the tool, first pull down the baffle 15, then place the 96-well deep-well plate into the placement box 1, then place the clamping assembly 13 on the right side of the 96-well deep-well plate. After closing the baffle 15, the telescopic spring 1302 will push and tighten to fix the 96-well deep-well plate. There is an infrared sensor on the movable push piece 5. When a well of sample is added, the infrared sensor sends a signal. The microcontroller 20 receives the signal and converts it to light up the LED lamp beads in the row positioning mark 7. In this way, the LED lamp beads of the corresponding row of each well will turn red after adding a well, thereby marking which rows in the current column have been loaded with samples. When all rows in a column have completed loading, push the movable push piece 5 to the right to display a new column of wells that need to be loaded with samples. Press the LED light button 16 to turn off the LED lamp beads of all row positioning marks 7, and then load each well.
[0044] After all samples are added, the microcontroller accumulates that the LED lamp beads of each row positioning mark 7 have been lit up 12 times, and then clears all the lighting times. The output end of the small electric push rod 10 extends to push the 96-well deep-well plate out through the push plate 11. According to the time when the timer button 18 is pressed and the current time, the elapsed time is displayed on the timer display screen 17, which is used to calculate the sample addition time, monitor efficiency, etc.
[0045] The above embodiments are not exhaustive of the present invention, and there may be many other embodiments not listed. Any replacements and improvements made without violating the concept of the present invention are within the scope of protection of the present invention.
Claims
1. A tool for preventing sample dislocation, characterized in that: The utility model comprises a placement box, wherein a U-shaped bar is fixedly connected to the top of the placement box, a first groove track is provided on the inner side of the U-shaped bar, a movable push piece is slidably connected to the inside of the first groove track, a second groove track is provided on the right side of the placement box, a baffle is slidably connected to the inside of the second groove track, an installation cavity is provided on the bottom surface of the placement box, a plurality of row positioning marks are provided on the first side of the upper surface of the U-shaped bar, a plurality of column positioning marks are provided on the second side of the upper surface of the U-shaped bar, a clamping assembly is provided on the right side of the installation cavity inside the placement box, an infrared sensor is provided on the left end of the movable push piece, and a microcontroller electrically connected to the row positioning mark and the infrared sensor is provided in the placement box.
2. The tool for preventing sample dislocation according to claim 1, wherein: The clamping assembly includes an abutment plate and a clamping plate, both of which are arranged inside the placement box. At least four telescopic springs are fixedly connected between the abutment plate and the clamping plate, and the outer side of the abutment plate abuts against the inner side of the baffle.
3. The tool for preventing sample dislocation according to claim 1, wherein: A clamping block is fixedly connected to the right side of the first groove track, and a limiting strip is fixedly connected to the left end of the movable push piece and the first groove track.
4. The tool for preventing sample dislocation according to claim 1, wherein: Four small electric push rods are fixedly installed on the bottom surface of the installation cavity, and the output ends of the four small electric push rods are fixedly connected to push plates.
5. The tool for preventing sample dislocation according to any one of claims 1 to 4, characterized in that: A battery compartment is provided on the bottom surface of the placement box and the left side of the installation cavity, and a cover plate is fixedly connected to the battery compartment via screws.
6. The tool for preventing sample dislocation according to any one of claims 1 to 4, characterized in that: A charging interface for charging is provided at a position corresponding to the battery compartment on the front side of the placement box.
7. The tool for preventing sample dislocation according to any one of claims 1 to 4, characterized in that: An LED light button is fixedly installed at the left end of the front side of the placement box, and a timer button is fixedly installed at the right end of the front side of the placement box.
8. The tool for preventing sample dislocation according to claim 1, wherein: A timer display screen is fixedly installed on the middle part of the front side of the placement box.
9. The tool for preventing sample dislocation according to any one of claims 1 to 3, characterized in that: The microcontroller is fixedly mounted in the middle of the bottom surface of the mounting cavity.
10. The tool for preventing sample loading dislocation according to claim 4, wherein: At least all of the row positioning marks among the column positioning marks and the row positioning marks are internally installed with LED lamp beads.