Tumor size measuring instrument for animal experiment

Abstract

The utility model belongs to the technical field of animal experiments, and particularly relates to a tumor size measuring instrument for animal experiments, one side of each clamping plate is provided with a clamping area and a measuring area, the clamping area is provided with a pressure sensor, the detection end of the pressure sensor and the measuring area are both flush with the clamping area, the number of the clamping plates is two, and the clamping plates are arranged in the measuring area. The two clamping plates are arranged in parallel and located at one end of the holding part, and the faces, provided with the clamping areas and the measuring areas, of the two clamping plates are oppositely arranged. The driving mechanism is arranged on the holding part and used for driving at least one clamping plate to move so that the two clamping plates can get close to each other or get away from each other. The distance measuring mechanism is used for measuring the distance between the measuring areas of the two clamping plates after the pressure sensors on the two clamping plates detect the pressure; the display screen is used for displaying the distance measured by the distance measuring mechanism. According to the utility model, the measurement efficiency and the measurement precision are improved, so that the experiment efficiency can be improved, the experiment error can be reduced as much as possible, and more accurate and effective experiment results can be obtained.

Description

Technical Field

[0001] The utility model belongs to the technical field of animal experiments, and particularly relates to a tumor size measuring instrument for animal experiments. Background Art

[0002] The morbidity and mortality rates of malignant tumors are increasing annually, posing a serious threat to human health and life. The establishment of animal tumor models, such as subcutaneous xenograft tumor models, provides powerful tools for studying the mechanisms of tumorigenesis and metastasis, as well as for screening and evaluating the efficacy of anticancer drugs. Tumor size (length, width, and height) measurement is essential for conducting research at various stages of an experiment. Inaccurate tumor size measurement can hinder the proper assessment of tumorigenesis, compromising the statistical power and reliability of subsequent experiments. Furthermore, in evaluating the efficacy of anticancer drugs, this can lead to misjudgment of drug effectiveness. For example, an effective drug may be misclassified as ineffective due to an inaccurate tumor volume measurement, and vice versa. When exploring biomarkers associated with tumor growth, inaccurate tumor size measurement can lead to erroneous associations between certain markers and tumor growth, misleading subsequent research directions. Therefore, the accuracy of tumor size measurement in animal tumor-related experiments has a significant impact on experimental results.

[0003] However, in the existing technology, a ruler is generally used to measure the tumor size of experimental animals. However, since the tumor is an irregular sphere, measurement is more troublesome, and the scale reading is subjective. Factors such as the measurer's visual angle and visual posture will affect the accuracy of the reading, resulting in errors being amplified and affecting the experimental results. Utility Model Content

[0004] The technical problem to be solved by the utility model is to provide a tumor size measuring instrument for animal experiments, which improves measurement efficiency and measurement accuracy and reduces experimental errors as much as possible.

[0005] The contents of this utility model include:

[0006] Grip;

[0007] A clamping plate, one side of which is provided with a clamping area and a measuring area, the clamping area is provided with a pressure sensor, the detection end and the measuring area of ​​the pressure sensor are flush with the clamping area, the clamping plate has two clamping plates, the two clamping plates are arranged in parallel and located at one end of the holding portion, and the clamping area and the measuring area of ​​the two clamping plates are arranged opposite each other;

[0008] A driving mechanism, provided on the gripping portion, for driving at least one of the clamping plates to move so that the two clamping plates move closer to or farther away from each other;

[0009] a distance measuring mechanism for measuring the distance between the measuring areas of the two clamping plates after the pressure sensors on the two clamping plates detect pressure;

[0010] A display screen is used to display the distance measured by the distance measuring mechanism.

[0011] Furthermore, the driving mechanism includes a motor, a screw and a nut, the screw is rotatably arranged on the holding part, the motor is arranged on the holding part and connected to the screw, the nut is arranged on the screw, and the movable splint is connected to the nut at one end away from the clamping area.

[0012] Furthermore, both of the clamping plates are movable.

[0013] Furthermore, there are two nuts, the threaded parts at both ends of the screw rod are opposite, the two nuts are correspondingly arranged on the threaded parts at both ends of the screw rod, and the two clamping plates have one end away from the clamping area correspondingly connected to the two nuts.

[0014] Furthermore, there are two motors, two screw rods and two nuts, both of which are rotatably arranged on the holding part, and the axes of the two screw rods are on the same straight line. The two motors are arranged on the holding part and are correspondingly connected to the two screw rods. The two nuts are correspondingly arranged on the two screw rods, and the two clamps have one end away from the clamping area and is correspondingly connected to the two nuts.

[0015] Furthermore, the driving mechanism is arranged inside the holding part, a guide groove is provided at one end of the holding part, and a guide slider is provided at the end of the movable splint away from the clamping area, the guide slider is inserted into the guide groove, and the driving mechanism drives the splint to move through the guide slider.

[0016] Furthermore, the distance measuring mechanism is a non-contact distance measuring sensor, which is arranged in a measuring area of ​​one of the clamping plates.

[0017] Furthermore, a mounting hole 1 is provided on the clamping area of ​​the two clamps, and the pressure sensor is arranged in the corresponding mounting hole 1; a mounting hole 2 is provided on the measuring area of ​​one clamp, and the non-contact ranging sensor is arranged in the mounting hole 2.

[0018] Furthermore, the display screen is arranged on the grip portion.

[0019] Furthermore, a scale is provided on one end of the gripping portion where the two clamps are located, and the scale is provided along the movable direction of the clamps.

[0020] The beneficial effect of this utility model is that, compared to the method of simply setting a scale in the area between two clamps and clamping the tumor area to be measured and reading the scale, the utility model can avoid the inconvenience of reading due to the clamps or the tumor area to be measured blocking the actual line of sight or the scale due to orientation problems. Measurement is convenient and fast, and it can more conveniently perform multi-dimensional dimensional measurements of the tumor area to be measured, respectively obtaining its length, width, height and other dimensional data, reducing measurement difficulty and avoiding the human error caused by scale reading. It improves measurement efficiency and measurement accuracy, thereby improving experimental efficiency, minimizing experimental errors, and obtaining more accurate and effective experimental results. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a schematic diagram of the structure of the tumor size measuring instrument for animal experiments of the present invention.

[0022] Figure 2 This is a structural diagram of the first configuration of the drive mechanism of the utility model.

[0023] Figure 3 This is a structural diagram of the second configuration of the drive mechanism of the present invention.

[0024] In the figure: 1. Grip; 11. Guide groove; 12. Push button switch; 13. Scale; 2. Clamp; 21. Pressure sensor; 22. Distance measuring mechanism; 23. Guide slider; 3. Drive mechanism; 31. Click; 32. Screw rod; 33. Nut; 4. Display screen. DETAILED DESCRIPTION

[0025] like Figure 1-Figure 3As shown, the present invention provides a tumor size measuring instrument for animal experiments, comprising a gripping portion 1, a clamping plate 2, a driving mechanism 3, a distance measuring mechanism 22, and a display screen 4. The gripping portion 1 is designed for the operator to grasp and is in the shape of a handle or other conveniently held shape. One side of the clamping plate 2 is provided with a clamping area and a measuring area. The clamping area is provided with a pressure sensor 21. The detection end and the measuring area of ​​the pressure sensor 21 are flush with the clamping area, that is, the detection end of the pressure sensor 21 is located on the same plane as the measuring area and the clamping area. There are two clamping plates 2, which are arranged parallel to each other and located at one end of the gripping portion 1. The sides of the two clamping plates 2 with the clamping and measuring areas are arranged opposite each other. The driving mechanism 3 is provided on the gripping portion 1 and is used to drive at least one of the clamping plates 2 to move the two clamping plates 2 closer to or farther from each other. The distance measuring mechanism 22 is used to stop the movement of the clamping plates 2 after the pressure sensors 21 on both clamping plates 2 detect pressure, and then measure the distance between the two clamping plates 2. The display screen 4 is used to display the distance measured by the distance measuring mechanism 22. The present invention further comprises a controller, and the pressure sensor 21, the driving mechanism 3, the distance measuring mechanism 22 and the display screen 4 are all electrically connected to the controller and work in coordination with each other through the controller.

[0026] When the present invention is used, the tumor area to be measured is positioned between the clamping areas of the two clamps 2. The drive mechanism 3 drives at least one of the clamps 2 to move, bringing the two clamps 2 closer together. When the two clamps 2 are close enough that their clamping areas contact the epidermis of the tumor area to be measured, the drive mechanism 3 stops when the pressure sensors 21 on the two clamps 2 detect pressure. The distance measuring mechanism 22 measures the distance between the two clamps 2 at this point and displays the measured distance value on the display screen 4, which is the size of the tumor area to be measured in this clamping orientation. Compared to a method of setting a scale only in the area between the two clamps 2 on the grip 1 and then reading the scale after clamping the tumor area to be measured, the present invention can avoid the inconvenience of reading caused by the clamps 2 or the tumor area to be measured blocking the actual line of sight or the scale due to orientation issues. Based on the foregoing, the present invention is quick and easy to measure, and can more conveniently perform multi-dimensional size measurements of the tumor area to be measured, and obtain its length, width, height and other size data respectively, thereby reducing the measurement difficulty and avoiding the human error caused by scale readings. It improves measurement efficiency while improving measurement accuracy, thereby improving experimental efficiency, minimizing experimental errors as much as possible, and obtaining more accurate and effective experimental results.

[0027] In the present invention, the drive mechanism 3 includes a motor, a screw 32, and a nut 33. The screw 32 is rotatably mounted on the gripping portion 1. The motor is mounted on the gripping portion 1 and connected to the screw 32. The nut 33 is mounted on the screw 32. The end of the movable clamping plate 2 facing away from the clamping area is connected to the nut 33. Specifically, the motor and the controller are electrically connected in the drive mechanism 3. Based on this arrangement, while meeting the requirements for the movement of the clamping plate 2, the drive mechanism 3 is powered by electricity, eliminating the need for an air source or hydraulic system, and reducing pipeline connections.

[0028] In one embodiment of the present invention, one clamping plate 2 is fixed and the other clamping plate 2 is movable.

[0029] In a preferred embodiment of the present invention, both of the splints 2 are movable. Compared with the previous embodiment, this embodiment does not require manual adjustment of the position until one of the splints 2 just contacts the epidermis of the tumor area to be measured to trigger a pressure signal. The two pressure sensors 21 trigger a pressure signal when they just contact the epidermis of the tumor area to be measured during the movement driven by the driving mechanism 3.

[0030] In the embodiment in which both the two clamping plates 2 are movable, one of the configurations of the present invention is as follows: Figure 2 As shown, there are two nuts 33, and the number of motors and screw rods 32 is one. The threaded parts at both ends of the screw rod 32 are opposite, and the two nuts 33 are correspondingly arranged on the threaded parts at both ends of the screw rod 32. The ends of the two clamping plates 2 that are away from the clamping area are correspondingly connected to the two nuts 33. In this setting mode, only one motor is needed to drive the two clamping plates 2 to move. Another setting mode of the utility model is as follows Figure 3 As shown, there are two motors, two screw rods 32, and two nuts 33. Both screw rods 32 are rotatably mounted on the gripping portion 1, and the axes of the two screw rods 32 are collinear, i.e., the extension of the axis of one screw rod 32 coincides with the axis of the other screw rod 32. Two motors are mounted on the gripping portion 1 and connected to the two screw rods 32, respectively. Two nuts 33 are mounted on the two screw rods 32, respectively. The ends of the two clamping plates 2 facing away from the clamping area are connected to the two nuts 33, respectively. This arrangement allows the two clamping plates 2 to move independently, providing greater flexibility and preventing one clamping plate 2 from applying excessive pressure to the tumor area to be measured.

[0031] The drive mechanism 3 is arranged inside the gripping portion 1, that is, the drive mechanism 3 and other structures are installed in the gripping portion 1. In one arrangement of the present invention, Figure 1As shown, a pressure sensor 21 is located at the upper end of the splint 2, and a distance measuring mechanism 22 is located at the lower end of the splint 2. Both the pressure sensor 21 and the distance measuring mechanism 22 are located outside the gripping portion 1. The length of the splint 2 is sufficient to clamp the tumor area to be measured without the epidermis being within the measurement range of the distance measuring mechanism 22. The end of the splint 2 facing away from the clamping area is the end where the measurement area is located. The gripping portion 1 is provided with a guide groove 11 at one end, and the length of the guide groove 11 is arranged along the movable direction of the splint 2. The end of the movable splint 2 facing away from the clamping area is provided with a guide slider 23. The guide slider 23 is inserted into the guide groove 11 and slidably engages with it. The driving mechanism 3 drives the splint 2 to move via the guide slider 23. In another setting of the present invention, the pressure sensor 21 is located at the upper end of the splint 2, the distance measuring mechanism 22 is located at the lower end of the splint 2, the pressure sensor 21 is located outside the holding portion 1, and the distance measuring mechanism 22 is located inside the holding portion 1. A guide groove 11 is provided at one end of the holding portion 1, and the length of the guide groove 11 is arranged along the movable direction of the splint 2. The measuring area on the splint 2 is located inside the holding portion 1. The position between the measuring area and the clamping area on the splint 2 slides with the guide groove 11. The end of the splint 2 that is away from the clamping area is the end where the measuring area is located. The end of the splint 2 that is away from the clamping area is connected to the nut 33, and the driving mechanism 3 drives the splint 2 to move through this end of the splint 2. Both of these settings can meet the use requirements, and the movement of the splint 2 can be guided by the width direction of the guide groove 11 to avoid lateral deviation of the splint 2 during movement.

[0032] The distance measuring mechanism 22 is a non-contact distance measuring sensor, which is arranged in the measuring area of ​​one of the clamping plates 2. The non-contact distance measuring sensor can be a laser distance measuring sensor or an infrared distance measuring sensor, and its distance measuring principle is prior art and will not be described in detail here.

[0033] The clamping areas of the two clamping plates 2 are provided with mounting holes 1, and the pressure sensors 21 are installed in the corresponding mounting holes 1. The measuring area of ​​one clamping plate 2 is provided with mounting holes 2, and the non-contact distance sensor is installed in the mounting holes 2. This ensures that the detection ends of the pressure sensors 21 and the non-contact distance sensor are flush with the surfaces of the clamping and measuring areas.

[0034] The display screen 4 can be externally mounted or integrated. When the display screen 4 is externally mounted, it is specifically mounted on an external controller. The controller is electrically connected to the electrical components on the grip 1. The power supply can be supplied by connecting a power outlet via a wire. The button switch 12 for turning on the measuring instrument is electrically mounted on the controller. In this arrangement, the arrangement of the controller, the display screen 4 and other components is not limited by the volume of the grip 1. When the display screen 4 is integrated, as shown in FIG. Figure 1As shown, the display screen 4 is provided on the grip 1. In this configuration, the controller is specifically a control board, which is built into the grip 1. A rechargeable battery is provided inside the grip 1. The battery is electrically connected to the control board to provide power. A button switch 12 for turning on the measuring instrument is provided on the surface of the grip 1 and is electrically connected to the control board. This configuration provides better integration of the measuring instrument and makes it easier to store and carry. In the above two configurations, the preset usage is as follows: press the button switch 12 once, the drive mechanism 3 drives the two splints 2 closer to each other. When both pressure sensors 21 detect pressure, the drive mechanism 3 stops moving the splints 2, the distance measuring mechanism 22 starts measuring the distance and displays it on the display screen 4. Press the button switch 12 again, and the drive mechanism 3 drives the two splints 2 away from each other and resets.

[0035] A scale 13 is provided on the grip portion 1 at one end where the two clamps 2 are located. The scale 13 is arranged along the movable direction of the clamps 2, that is, along the line connecting the two clamps 2, and is located at the edge of the guide slot 11. The zero position of the scale 13 is set at the center point of the line connecting the two clamps 2 at this end of the grip portion 1, and the two ends of the scale 13 extend along this center point toward the position of the two clamps 2. The readings of the two clamps 2 at both ends of the scale 13 are read separately, and then added together to obtain the distance between the two clamps 2. Based on this arrangement, it can be used to assist operators in judging the accuracy of the distance measuring sensor during routine calibration or maintenance of the instrument.

[0036] Those skilled in the art should understand that the discussion of any of the above embodiments is merely illustrative and is not intended to imply that the scope of protection of the present application is limited to these examples. In line with the present application, the technical features in the above embodiments or different embodiments may be combined, the steps may be implemented in any order, and there are many other variations of different aspects of one or more embodiments of the present application as described above, which are not provided in detail for the sake of simplicity.

[0037] The one or more embodiments of this application are intended to encompass all such substitutions, modifications, and variations that fall within the broad scope of this application. Therefore, any omissions, modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of one or more embodiments of this application should be included in the scope of protection of this application.

Claims

1. A tumor size measuring instrument for animal experiments, characterized in that: include: A grip portion (1); A clamping plate (2), one side of the clamping plate (2) is provided with a clamping area and a measuring area, the clamping area is provided with a pressure sensor (21), the detection end and the measuring area of ​​the pressure sensor (21) are both flush with the clamping area, the clamping plate (2) has two clamping plates (2), the two clamping plates (2) are arranged in parallel and located at one end of the holding portion (1), and the clamping area and the measuring area of ​​the two clamping plates (2) are arranged opposite to each other; A driving mechanism (3), the driving mechanism (3) comprising a motor, a screw rod (32) and a nut (33), wherein the motor, the screw rod (32) and the nut (33) each have two, the two screw rods (32) are rotatably arranged on the holding portion (1), and the axes of the two screw rods (32) are on the same straight line, the two motors are arranged on the holding portion (1) and are correspondingly connected to the two screw rods (32), the two nuts (33) are correspondingly arranged on the two screw rods (32), and the ends of the two clamping plates (2) facing away from the clamping area are correspondingly connected to the two nuts (33), so that both clamping plates (2) can move; A distance measuring mechanism (22) is used to measure the distance between the measuring areas of the two clamping plates (2) after the pressure sensors (21) on the two clamping plates (2) detect pressure; The display screen (4) is used to display the distance measured by the distance measuring mechanism (22).

2. The tumor size measuring instrument for animal experiments according to claim 1, wherein: The driving mechanism (3) is arranged inside the holding portion (1), and a guide slide groove (11) is provided at one end of the holding portion (1). A guide slider (23) is provided at the end of the movable clamping plate (2) away from the clamping area, and the guide slider (23) is inserted into the guide slide groove (11). The driving mechanism (3) drives the clamping plate (2) to move via the guide slider (23).

3. The tumor size measuring instrument for animal experiments according to claim 1, wherein: The distance measuring mechanism (22) is a non-contact distance measuring sensor, which is arranged in a measuring area of ​​one of the clamping plates (2).

4. The tumor size measuring instrument for animal experiments according to claim 3, wherein: The clamping areas of the two clamping plates (2) are provided with mounting holes one, and the pressure sensors (21) are arranged in the corresponding mounting holes one; the measuring area of ​​one clamping plate (2) is provided with mounting holes two, and the non-contact distance measuring sensor is arranged in the mounting holes two.

5. The tumor size measuring instrument for animal experiments according to any one of claims 1 to 4, characterized in that: The display screen (4) is arranged on the gripping portion (1).

6. The tumor size measuring instrument for animal experiments according to any one of claims 1 to 4, characterized in that: A scale (13) is provided on one end of the gripping portion (1) where the two clamps (2) are located, and the scale (13) is provided along the movable direction of the clamps (2).

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