96-well plate

Abstract

The utility model discloses a 96-well plate which comprises a plate body, the upper side of the plate body is covered with a sealing cover in fit sliding connection, a fit plate is arranged at the top of the inner side of the sealing cover in a limiting sliding mode, the top face of the fit plate is horizontal and keeps sliding vertically, pressure applying conical heads which are distributed at equal intervals are fixed to the top face of the fit plate, and the pressure applying conical heads are fixed to the top face of the fit plate. Elastic columns which are annularly distributed at equal intervals are fixed to the inner wall of the sealing cover and located over the pressure applying conical head, the top of the pressure applying conical head is arranged between the elastic columns in a penetrating mode, and the outer wall of the pressure applying conical head is elastically connected with the elastic columns in a sliding mode in an attached mode; according to the utility model, the laminating plate can be pressed to be completely laminated with the top surface of the hole by using the covering pressure of the sealing cover, so that the problem of inaccurate experiment result caused by hole crossing due to volatilization of a sample in the hole in the experiment process is completely avoided, and meanwhile, the laminating plate and the sealing cover have single-point pressure application, so that the laminating plate can be ensured to be completely laminated with the surface of the hole.

Description

Technical Field

[0001] The utility model relates to the technical field of 96-well plates, in particular to a 96-well plate. Background Art

[0002] The 96-well plate is a laboratory instrument widely used in fields such as biochemistry, molecular biology, and drug screening. Made from imported, optically transparent pure polystyrene and sterilized with gamma rays to ensure sterility, the 96-well plate is typically made from polymers such as polypropylene (PP) or polystyrene (PS). It exhibits excellent chemical compatibility and can be used with a variety of polar organic solvents, acidic and alkaline solutions. Its design allows experimenters to process up to 96 samples simultaneously, significantly improving experimental efficiency. Furthermore, the 96-well plate's excellent sealing properties effectively prevent sample volatilization and cross-contamination.

[0003] During the use of 96-well plates, some of the various sample experiments in the wells need to be sealed to prevent sample volatilization from affecting adjacent samples. However, with ordinary sealing, it is inevitable that some positions between the 96 wells will not be completely fitted, resulting in multiple wells being connected, affecting the experimental results. Therefore, it is urgent to design a 96-well plate to solve the above problems. Utility Model Content

[0004] To solve the above technical problems, the present invention provides a 96-well plate that can apply pressure to cover the 96 wells so that all positions of the 96 wells can be sealed, thereby improving the accuracy of sample experiments inside the 96-well plate.

[0005] The 96-well plate provided by the utility model:

[0006] The utility model comprises a plate body, wherein the upper side of the plate body is covered with a sealing cover which is fitted and slidably connected, a fitting plate is provided on the top inner side of the sealing cover for limiting sliding, the top surface of the fitting plate is horizontal and keeps sliding vertically, the top surface of the fitting plate is fixed with equidistantly arranged pressure cone heads, the inner wall of the sealing cover is directly above the pressure cone heads and is fixed with annularly equidistantly distributed elastic columns, the top of the pressure cone heads is passed through between the elastic columns, and the outer wall of the pressure cone heads is elastically and slidably connected to the elastic columns.

[0007] Preferably, symmetrical elastic hooks are fixed to the bottom of both sides of the sealing cover, and the bottom ends of the elastic hooks are elastically hooked on the inner side of the outer wall of the plate body. The setting of the elastic hooks can make the sealing cover and the plate body integrated by the elastic hooks at the bottom of the elastic hooks after the sealing cover and the plate body are covered, thereby ensuring the sealing effect of the sealing cover fitting the top surface of the 96 holes inside the plate body.

[0008] Preferably, a limit stop ring is fixed in the middle of the inner wall of the sealing cover, and the outer wall of the bottom surface of the bonding plate is bonded to the top surface of the limit stop ring. The limit stop ring can block the bonding plate inside the sealing cover when the sealing cover is not in use, thereby improving the convenience of using the bonding plate.

[0009] Preferably, a horizontal baffle is vertically fixed at the edge of the top surface of the bonding plate, and the outer wall of the horizontal baffle slides in contact with the inner wall of the sealing cover. The horizontal baffle connected to the outer wall of the top surface of the bonding plate can increase the side wall height of the bonding plate, thereby increasing the bonding area between the bonding plate and the inner wall of the sealing cover, and improving the horizontality of the bonding plate sliding up and down.

[0010] Preferably, 96 holes are provided on the inner side of the top surface of the plate body, and the position where the pressure cone head is connected to the bonding plate is located directly above the plane of the staggered positions between the 96 holes. The pressure cone head is located directly above the plane of the staggered positions of the 96 holes, so that when the bonding plate is bonded to the top surface of the plate body, the pressure cone head can just apply pressure to the plane between the 96 holes, thereby improving the sealing effect between the 96 holes.

[0011] Preferably, a lifting seat is fixed at the center of the top surface of the sealing cover, and a universal ball is rotatably connected to the inner side of the top of the lifting seat. A lifting ring is hinged at the center of the top of the universal ball. The lifting seat at the center of the top surface of the sealing cover can cooperate with the universal ball, so that when the sealing cover is removed or moved, the lifting ring is directly pulled to make the sealing cover horizontal and drive the plate body to move, thereby ensuring the smooth movement of the samples inside the 96 holes.

[0012] Compared with related technologies, the 96-well plate provided by the present invention has the following beneficial effects:

[0013] 1. The utility model is provided with a sealing cover on the upper part of the plate body, which can completely cover the 96 wells of the plate body and use the covering pressure to press the bonding plate to completely fit the top surface of the 96 wells, thereby completely avoiding the problem of cross-holes caused by the volatilization of samples in the 96 wells during the experiment, which leads to inaccurate experimental results. At the same time, the bonding plate and the sealing cover have single-point pressure to ensure that the surface between the bonding plate and the 96 wells is completely fitted.

[0014] 2. The top surface of the bonding plate is provided with a pressure cone head corresponding to the staggered plane between the 96 holes, and an elastic column is provided on the inner wall of the sealing cover. When the bonding plate is pressed down, the elastic column applies a thrust to the pressure cone head, thereby improving the fit between the staggered plane between the bonding plate and the 96 holes and ensuring long-term stable fit. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 A schematic structural diagram of a preferred embodiment of a 96-well plate provided by the present invention;

[0016] Figure 2 for Figure 1A schematic diagram of the structure of the middle section shown;

[0017] Figure 3 for Figure 2 The structure of the sealing cover is shown in the exploded and enlarged schematic diagram;

[0018] Figure 4 for Figure 1 The structure of the elastic hook position is shown in the exploded and enlarged schematic diagram.

[0019] Numbers in the figure: 1. Plate body; 2. Sealing cover; 3. Fitting plate; 4. Pressure cone head; 5. Elastic column; 6. Elastic hook; 7. Limiting ring; 8. Horizontal retaining frame; 9. 96 holes; 10. Lifting seat; 11. Universal ball; 12. Lifting ring. DETAILED DESCRIPTION

[0020] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0021] The specific implementation of the present invention is described in detail below with reference to specific embodiments.

[0022] Please see the attached Figures 1-4 The 96-well plate provided in the embodiment of the present invention comprises:

[0023] The plate body 1 has 96 wells 9 on its top surface. The 96 wells 9 can hold 96 groups of samples, providing ample experimental space for the samples while maintaining separation between the samples.

[0024] A sealing cover 2 is provided on the upper part of the plate body 1, which can cover the plate body 1 to ensure the sealing of the space inside the upper part of the plate body 1. A bonding plate 3 is provided on the upper side of the sealing cover 2 to limit vertical sliding. The bonding plate 3 itself is in a horizontal state. The bottom surface of the bonding plate 3 is bonded to the top surface of the plate body 1 to cover and seal the 96 holes 9. The bonding plate 3 covering the 96 holes 9 can ensure that the 96 holes 9 are completely sealed, and there will be no connection between the 96 holes 9, thereby improving the accuracy of the sample experimental results inside the 96 holes 9.

[0025] A pressure cone head 4 is provided on the top surface of the bonding plate 3, directly above the plane at the staggered position between the 96 holes 9, and a plurality of groups of elastic columns 5 are fixed on the inner side of the sealing cover 2, directly above the pressure cone head 4, in a circular but equidistantly distributed manner. The elastic columns 5 are arranged corresponding to the pressure cone head 4, and the pressure cone head 4 is passed through the center of the elastic column 5 of the circular design. At the same time, the outer wall of the pressure cone head 4 is elastically connected to the plurality of elastic columns 5.

[0026] When the sealing cover 2 is closed, the bonding plate 3 will contact the top surface of the plate body 1. At this time, as the sealing cover 2 is closed, the bonding plate 3 will move up inside the sealing cover 2, and then the pressure cone head 4 will be connected to the elastic column 5, so that the elastic column 5 can apply downward pressure on the bonding plate 3 for the pressure cone head 4, so that the bonding plate 3 can be pressed against the plane between the 96 holes 9 on the top surface of the plate body 1, ensuring that all 96 holes 9 can be completely sealed with each other.

[0027] A limit ring 7 is provided in the middle of the inner wall of the sealing cover 2. The limit ring 7 can keep the bonding plate 3 inside the sealing cover 2 when the sealing cover 2 is not in use, thereby avoiding separation of the bonding plate 3 from the sealing cover 2, reducing the bonding operation between the bonding plate 3 and the plate body 1, and making the use of this device more convenient and efficient.

[0028] The horizontal retaining frame 8 provided on the outer wall of the top surface of the bonding plate 3 can increase the side height of the bonding plate 3, thereby increasing the contact area between the side of the bonding plate 3 and the inner wall of the sealing cover 2, so that the bonding plate 3 can maintain a more stable horizontal lifting effect when moving.

[0029] A lifting seat 10 is connected to the center of the top surface of the sealing cover 2, and a universal ball 11 is rotatably connected to the center of the top surface of the lifting seat 10. A lifting ring 12 is hinged on the top of the universal ball 11. The setting of the lifting ring 12 and the universal ball 11 allows the sealing cover 2 to be moved horizontally by pulling the lifting ring 12 when moving.

[0030] Furthermore, when the sealing cover 2 is pulled to drive the plate body 1 to move, the horizontal sealing cover 2 can drive the plate body 1 to move horizontally, thereby ensuring the stability of the samples inside the 96 wells 9.

[0031] When the bottom of the sealing cover 2 contacts the plate body 1, the elastic hook 6 provided on the side of the sealing cover 2 will be grooved into the side hook groove of the plate body 1, and the sealing cover 2 will be opened. Figure 4 It can be seen that at this time, the plate body 1 and the sealing cover 2 are integrated into one, completing the complete sealing of the 96 holes 9 inside the plate body 1.

[0032] Usage process:

[0033] After placing the sample inside the 96 holes 9 on the top surface of the plate body 1, the sealing cover 2 can be covered on the outside of the plate body 1 if sealing is required. During the covering process, as the sealing cover 2 descends, the fitting plate 3 inside the sealing cover 2 will fit with the top surface of the plate body 1, and the 96 holes 9 are covered with the fitting plate 3. As the sealing cover 2 continues to descend, the pressure cone head 4 on the top surface of the fitting plate 3 will contact the elastic column 5 on the top surface of the sealing cover 2. When the bottom end of the sealing cover 2 fits with the plate body 1, the pressure cone head 4 will penetrate between the elastic columns 5. At this time, the elastic column 5 will apply an elastic thrust to the pressure cone head 4, allowing the pressure cone head 4 to apply pressure to the plane between the 96 holes 9, thereby completing the complete sealing between the 96 holes 9, ensuring the experimental sealing of the samples inside the 96 holes, and improving the accuracy of the experimental results.

[0034] The circuits and controls involved in the present invention are all prior art and will not be described in detail here.

[0035] The above description is merely an embodiment of the present invention and does not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the contents of the description and drawings of the present invention, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. 96-well plate, characterized in that The invention comprises a plate body (1), wherein the upper side of the plate body (1) is covered with a sealing cover (2) which is fitted and slidably connected to the outer wall of the side of the plate body (1), the inner top of the sealing cover (2) is provided with a fitting plate (3) for limiting sliding, the top surface of the fitting plate (3) is horizontal and keeps vertical sliding, the top surface of the fitting plate (3) is fixed with equidistantly arranged pressure cone heads (4), the inner wall of the sealing cover (2) is located directly above the pressure cone heads (4) and is fixed with annular equidistantly distributed elastic columns (5), the top of the pressure cone heads (4) is passed through between the elastic columns (5), and the outer wall of the pressure cone heads (4) is fitted and elastically slidably connected to the elastic columns (5).

2. The 96-well plate according to claim 1, wherein Symmetrical elastic hooks (6) are fixed to the bottoms of both sides of the sealing cover (2), and the bottom ends of the elastic hooks (6) are elastically hooked to the inner side of the outer wall of the plate body (1).

3. The 96-well plate according to claim 1, wherein A limit stop ring (7) is fixed to the middle of the inner wall of the sealing cover (2), and the outer wall of the bottom surface of the bonding plate (3) is bonded to the top surface of the limit stop ring (7).

4. The 96-well plate according to claim 1, wherein A horizontal retaining frame (8) is vertically fixed at the edge of the top surface of the laminating plate (3), and the outer wall of the horizontal retaining frame (8) is fitted and slid on the inner wall of the sealing cover (2).

5. The 96-well plate according to claim 1, wherein 96 holes (9) are provided on the inner side of the top surface of the plate body (1), and the position where the pressure cone head (4) is connected to the bonding plate (3) is located directly above the plane of the staggered positions between the 96 holes (9).

6. The 96-well plate according to claim 1, wherein A lifting seat (10) is fixed at the center of the top surface of the sealing cover (2), a universal ball (11) is rotatably connected to the inner side of the top of the lifting seat (10), and a lifting ring (12) is hinged at the center of the top of the universal ball (11).

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