Tooth comb for adjusting dosage of laboratory protein

Abstract

The utility model discloses a tooth comb for adjusting laboratory protein dosage, which relates to the technical field of electrophoresis combs and comprises a tooth comb base body and a comb tooth group, the comb tooth group comprises two fixed comb teeth and a plurality of movable comb teeth, the movable comb teeth are mounted on the tooth comb base body in a sliding manner, and the fixed comb teeth and the movable comb teeth are arranged on the tooth comb base body. A first tooth comb cover plate and a second tooth comb cover plate are slidably mounted on the two sides of the tooth comb base body respectively, first limiting grooves and second limiting grooves corresponding to the movable comb teeth are formed in the end faces, close to the tooth comb base body, of the first tooth comb cover plate and the second tooth comb cover plate in a multi-equally-divided mode respectively, and the number of the first limiting grooves is different from that of the second limiting grooves. The device can be used for adjusting the dosage of protein samples in a laboratory, can adjust the width of the experimental sample groove by changing the interval of the movable comb teeth, adapts to different sample adding amounts, and optimizes electrophoresis results; the movable comb teeth are effectively prevented from randomly moving to influence the forming of the concentrated gel sample loading hole, and meanwhile, unformed gel can be prevented from flowing into the comb from gaps among the movable comb teeth to corrode the comb.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of electrophoresis comb, especially to a tooth comb for adjusting the protein dosage of laboratory. BACKGROUND

[0002] Polyacrylamide gel electrophoresis has a wide range of uses in the research field of protein separation and identification due to its simple operation and good repeatability. In most laboratories, polyacrylamide gels are prepared according to actual needs, and the inherent mold "electrophoresis comb" plays a key role in the preparation of polyacrylamide gels. In the prior art, the electrophoresis comb can only be made into a fixed number of polyacrylamide gel lanes, and the protein loading amount is generally fixed, so it is not possible to freely select the number of lanes and the corresponding loading amount.

[0003] To improve the above problems, through retrieval, a kind of electrophoresis comb provided by patent announcement No.CN206556970U, electrophoresis comb includes comb base body and the comb tooth containing magnetic material, comb base body is equipped with recess, comb tooth is detachably arranged in recess. The polyacrylamide gel prepared by using the electrophoresis comb can be most conveniently and quickly adapted to various experimental requirements of different laboratories, and is very easy to operate. It can prepare polyacrylamide gels with different lanes and corresponding sample volumes.

[0004] Based on the above retrieval, combined with the prior art, it is found that the relative fixed mode of the above disclosed electrophoresis comb in the prior art has poor stability, and the two movable comb teeth adjacent to each other are easily attracted to each other, increasing the error of the comb tooth spacing. Therefore, a tooth comb for adjusting the protein dosage of laboratory is proposed to improve the above problems. UTILITY MODEL CONTENTS

[0005] The purpose of the present application is to provide a tooth comb for adjusting the protein dosage of laboratory to solve the problems raised in the background art.

[0006] To achieve the above purpose, the present application provides the following technical scheme: a tooth comb for adjusting the protein dosage of laboratory, comprising a tooth comb base body and a comb tooth group:

[0007] The comb tooth group comprises two fixed comb teeth and a plurality of movable comb teeth, the two fixed comb teeth are integrally arranged on both sides of the tooth comb base body respectively, and the plurality of movable comb teeth are located between the two fixed comb teeth and are slidingly installed on the tooth comb base body along the length direction of the tooth comb base body;

[0008] A first tooth comb cover plate is slidingly installed on one side of the tooth comb base body along the width direction thereof, and a second tooth comb cover plate is slidingly installed on the other side of the tooth comb base body along the width direction thereof;

[0009] The first and second tooth comb cover plates are respectively provided with first and second limiting grooves corresponding to the plurality of movable comb teeth at the end faces close to the tooth comb base, and the number of the first limiting grooves is different from that of the second limiting grooves.

[0010] As a further supplement to the scheme, the movable comb teeth are fixed with movable clamping seats close to the end of the tooth comb base, the movable clamping seats are slidingly clamped at the side ends of the tooth comb base, and the two side ends of the movable clamping seat away from the movable comb teeth are integrally provided with limiting sliding blocks one, and the two sides of the tooth comb base are provided with first limiting sliding grooves slidingly matched with the limiting sliding blocks one.

[0011] The width of the first limiting groove is consistent with the width of one movable clamping seat, and the width of the second limiting groove is consistent with the sum of the widths of the plurality of movable clamping seats.

[0012] As a further supplement to the scheme, the first and second limiting grooves are provided with chamfers close to the side slots of the movable clamping seat.

[0013] As a further supplement to the scheme, the first and second tooth comb cover plates are integrally provided with limiting sliding blocks two close to the two ends of the side of the tooth comb base, and the two sides of the tooth comb base are provided with second limiting sliding grooves slidingly matched with the limiting sliding blocks two.

[0014] As a further supplement to the scheme, the two sides of the tooth comb base are rotatably provided with adjusting screws, one of the adjusting screws is threaded through the first tooth comb cover plate, and the other adjusting screw is threaded through the second tooth comb cover plate.

[0015] As a further supplement to the scheme, the first and second tooth comb cover plates are fixed with magnetic attraction pieces away from the end faces of the tooth comb base.

[0016] In summary, the technical effects and advantages of the utility model are as follows:

[0017] 1、In the utility model, through the cooperation of the movable comb teeth, the first and second tooth comb cover plates, and the first limiting grooves on the first tooth comb cover plate and the second limiting grooves on the second tooth comb cover plate, the plurality of movable comb teeth can be in a stable and equal division state, can be applied to laboratory adjustment of protein sample dosage, can adjust the experimental sample groove width by changing the interval of the movable comb teeth, is suitable for different sample addition amounts, and optimizes electrophoresis results.

[0018] 2. The utility model discloses, through the cooperation of movable comb tooth, first tooth comb cover plate, second tooth comb cover plate and the first limiting slot on the first tooth comb cover plate and the second limiting slot on the second tooth comb cover plate, can make multiple movable comb tooth be in stable equal division state, effectively prevent movable comb tooth from moving at will and influence the forming of concentrated glue sample hole, can prevent the unformed gel from flowing into the tooth comb and corroding the tooth comb from the gap between movable comb tooth simultaneously. BRIEF DESCRIPTION OF DRAWINGS

[0019] In order to more clearly illustrate the technical scheme in the embodiments of the present application or the prior art, the drawings needed to be used in the embodiments or prior art description will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can also be obtained according to these drawings without creative labor for those skilled in the art.

[0020] Figure 1 It is a front structure schematic view in the embodiment of the present application in the equal interval distribution state of movable comb tooth.

[0021] Figure 2 It is a front structure schematic view in the embodiment of the present application in the equal interval distribution state of movable comb tooth. Figure 1

[0022] Figure 3 It is a front structure schematic view in the embodiment of the present application in the equal interval distribution state of movable comb tooth.

[0023] Figure 4 It is a front structure schematic view in the embodiment of the present application in the equal interval distribution state of movable comb tooth. Figure 3

[0024] Figure 5 It is a front structure schematic view in the embodiment of the present application in the equal interval distribution state of movable comb tooth.

[0025] Figure 6 It is a front structure schematic view in the embodiment of the present application in the equal interval distribution state of movable comb tooth.

[0026] Figure 7 It is a front structure schematic view in the embodiment of the present application in the equal interval distribution state of movable comb tooth.

[0027] In the drawing: 1, tooth comb base; 101, first limiting sliding groove; 102, second limiting sliding groove; 2, fixed comb tooth; 3, movable comb tooth; 4, movable clamp seat; 5, limiting sliding block one; 6, first tooth comb cover plate; 601, first limiting slot; 7, second tooth comb cover plate; 701, second limiting slot; 8, limiting sliding block two; 9, adjusting screw. DETAILED DESCRIPTION

[0028] ​​Clearly and completely describe the technical scheme in the embodiments of the utility model with reference to the drawings in the embodiments of the utility model, obviously, the described embodiments are only some embodiments of the utility model, not all embodiments. Based on the embodiments in the utility model, all other embodiments obtained by the ordinary skilled in the art without creative labor belong to the scope of protection of the utility model.

[0029] Embodiment: refer to Figures 1-7 The utility model discloses a tooth comb for adjusting laboratory protein dosage, including tooth comb base body 1 and comb tooth group.

[0030] Among them, the comb tooth group includes two fixed combs 2 and a plurality of movable combs 3, two fixed combs 2 are vertically integrated to be arranged on the both sides of tooth comb base body 1 respectively, and a plurality of movable combs 3 are located between the two fixed combs 2 and are slidably installed on tooth comb base body 1 along the length direction of tooth comb base body 1, and the gap between movable combs 3 can be adjusted according to actual needs.

[0031] Regarding the sliding installation design between movable comb 3 and tooth comb base body 1, specifically, movable comb 3 is fixed with movable clamp seat 4 close to the end of tooth comb base body 1, movable clamp seat 4 is slidably clamped on the side end of tooth comb base body 1, and limit sliding block one 5 is integrally arranged on the two side ends of movable clamp seat 4 away from movable comb 3, and the both sides of tooth comb base body 1 are provided with first limit sliding groove 101 slidably matched with limit sliding block one 5, as Figure 7 Limit sliding block one 5 is inverted L-shaped, which can effectively prevent it from being separated from first limit sliding groove 101.

[0032] In order to relatively fix movable comb 3 and tooth comb base body 1, first tooth comb cover plate 6 is slidably installed on one side of tooth comb base body 1 along the width direction thereof, and second tooth comb cover plate 7 is slidably installed on the other side of tooth comb base body 1 along the width direction thereof, wherein first tooth comb cover plate 6 and second tooth comb cover plate 7 are respectively divided into multiple first limit grooves 601 and second limit grooves 701 corresponding to a plurality of movable combs 3 close to the end face of tooth comb base body 1, and the number of first limit grooves 601 is different from that of second limit grooves 701, the width of first limit groove 601 is consistent with the width of one movable clamp seat 4, and the width of second limit groove 701 is consistent with the sum of the widths of a plurality of movable clamp seats 4, and first tooth comb cover plate 6 and second tooth comb cover plate 7 relatively fix movable comb 3 and tooth comb base body 1 through first limit groove 601 and second limit groove 701 respectively.

[0033] Due to the number of first limiting grooves 601 is different from the number of second limiting grooves 701, specifically, taking 13 movable combs 3, 13 first limiting grooves 601 and 5 second limiting grooves 701 as an example: in use, 13 first limiting grooves 601 on the first comb cover plate 6 are used to correspondingly clamp 13 movable combs 3, forming a type of comb shape; 5 second limiting grooves 701 on the second comb cover plate 7 are used to equally clamp 13 movable combs 3 and two fixed combs 2 (two fixed combs 2 correspond to two movable combs 3 to form two groups of comb parts, and the remaining 9 movable combs 3 form 3 groups of comb parts according to 3 in a group), forming another type of comb shape.

[0034] The above two kinds of comb cover plates can prevent the movable combs 3 from moving at will and affecting the formation of the concentrated glue sample hole, and can also prevent unformed gel from flowing into the comb from the gap between the movable combs 3 to corrode the comb.

[0035] Regarding the sliding installation design between the first comb cover plate 6 and the second comb cover plate 7 and the comb base 1, specifically, the first comb cover plate 6 and the second comb cover plate 7 are integrally provided with limiting sliding blocks two 8 at both ends of the side close to the comb base 1, and the two sides of the comb base 1 are provided with second limiting sliding grooves 102 which are slidingly matched with the limiting sliding blocks two 8, as shown in Figure 5 It is shown that the limiting sliding blocks two 8 are T-shaped, which can effectively prevent them from being separated from the second limiting sliding grooves 102.

[0036] Among them, as shown in Figure 5 It is shown that the first limiting grooves 601 and the second limiting grooves 701 are provided with chamfers at the side slots close to the movable clamping seat 4, and the chamfers can increase the fault tolerance in the process of clamping the movable combs 3 into the first limiting grooves 601 and the second limiting grooves 701, and the adjustment is more convenient.

[0037] In order to enable the first comb cover plate 6 and the second comb cover plate 7 to stably limit the movable combs 3, the two sides of the comb base 1 are rotatably installed with adjusting screws 9, one of which is threaded through the first comb cover plate 6, and the other is threaded through the second comb cover plate 7.

[0038] In use, the experimenter only needs to manually turn the corresponding adjusting screw 9 on the first comb cover plate 6 or the second comb cover plate 7, which can drive the first comb cover plate 6 or the second comb cover plate 7 to move along the width direction of the comb base 1, so as to relatively fix the movable combs 3 with the comb base 1, which is more stable and reliable.

[0039] In addition, in order to facilitate stable placement of the tooth comb, the first tooth comb cover plate 6 and the second tooth comb cover plate 7 are fixed with magnetic attraction pieces (not shown in the figure) away from the end face of the tooth comb base 1, which facilitates the stable adsorption of the tooth comb on the ferromagnetic shelf or shelf plate by the magnetic attraction pieces, and the storage is more convenient.

[0040] The utility model discloses working principle: with 13 movable combs 3, 13 first limit slots 601 and 5 second limit slots 701 for example:

[0041] When using, the experimenter moves 13 movable combs 3 to thirteen equal division states, then manually twists the adjusting screw 9 corresponding on the first tooth comb cover plate 6, and 13 first limit slots 601 on the first tooth comb cover plate 6 are respectively corresponded 13 movable combs 3 and are clamped, and the tooth comb shape of a use type is formed;

[0042] The experimenter moves 13 movable combs 3 with two fixed combs 2 to five equal division states, then manually twists the adjusting screw 9 corresponding on the second tooth comb cover plate 7, and 5 second limit slots 701 on the second tooth comb cover plate 7 are divided and clamped 13 movable combs 3 and two fixed combs 2 (two fixed combs 2 respectively correspond two movable combs 3 and form two groups of comb parts, and the remaining 9 movable combs 3 form 3 groups of comb parts according to 3 one group), and the tooth comb shape of another use type is formed.

[0043] The tooth comb in the scheme is applied to the laboratory adjustment protein sample dosage, the interval between movable combs 3 is adjusted, the experimental sample groove width is adjusted, different sample adding amounts can be adapted, and electrophoresis results are optimized.

[0044] Finally, it should be noted that: the above only for preferred embodiment of the utility model, and does not limit the utility model, although the utility model has been described in detail with reference to the foregoing embodiments, for the person skilled in the art, still can modify the technical scheme recorded in the foregoing each embodiment, or equivalent replacement to part of technical features, any modification, equivalent replacement, improvement etc. that is made within the spirit and principles of the utility model, should be included in the protection scope of the utility model.

Claims

1. A tooth comb for adjusting the amount of protein used in a laboratory, comprising a tooth comb base (1) and a comb tooth group, characterized in that: The comb teeth group comprises two fixed comb teeth (2) and a plurality of movable comb teeth (3), the two fixed comb teeth (2) are respectively and vertically integrated on both sides of the tooth comb base (1), and the plurality of movable comb teeth (3) are all located between the two fixed comb teeth (2) and are slidably mounted on the tooth comb base (1) along the length direction of the tooth comb base (1); A first tooth comb cover plate (6) is slidably mounted on one side of the tooth comb base (1) along its width direction, and a second tooth comb cover plate (7) is slidably mounted on the other side of the tooth comb base (1) along its width direction; The first tooth comb cover plate (6) and the second tooth comb cover plate (7) are respectively provided with a first limiting groove (601) and a second limiting groove (701) corresponding to the plurality of movable comb teeth (3) at the end surfaces close to the tooth comb base (1), and the number of the first limiting grooves (601) is different from the number of the second limiting grooves (701). The first tooth comb cover plate (6) and the second tooth comb cover plate (7) respectively fix the movable comb teeth (3) relative to the tooth comb base (1) through the first limiting groove (601) and the second limiting groove (701).

2. A tooth comb for adjusting the amount of protein used in a laboratory according to claim 1, characterized in that: A movable card seat (4) is fixed to the end of the movable comb teeth (3) close to the tooth comb base (1), and the movable card seat (4) is slidably clamped on the side end of the tooth comb base (1). The two side ends of the movable card seat (4) away from the movable comb teeth (3) are integrally provided with a limiting slider (5), and both sides of the tooth comb base (1) are provided with a first limiting sliding groove (101) that is slidably adapted to the limiting slider (5); The width of the first limiting groove (601) is consistent with the width of one movable card seat (4), and the width of the second limiting groove (701) is consistent with the sum of the widths of multiple movable card seats (4).

3. A tooth comb for adjusting the amount of protein used in a laboratory according to claim 2, characterized in that: The first limiting groove (601) and the second limiting groove (701) are provided with chamfers at the notches on one side close to the movable card seat (4).

4. The tooth comb for adjusting the amount of protein used in a laboratory according to claim 1, characterized in that: The first tooth comb cover plate (6) and the second tooth comb cover plate (7) are both integrally provided with a limiting slider (8) at both ends of one side close to the tooth comb base (1), and both sides of the tooth comb base (1) are provided with a second limiting sliding groove (102) that is slidably adapted to the limiting slider (8).

5. The tooth comb for adjusting the amount of protein used in a laboratory according to claim 1, characterized in that: Adjusting screws (9) are rotatably mounted on both sides of the tooth comb base (1), one of the adjusting screws (9) is threadedly passed through the first tooth comb cover plate (6), and the other adjusting screw (9) is threadedly passed through the second tooth comb cover plate (7).

6. The tooth comb for adjusting the amount of protein used in a laboratory according to claim 1, characterized in that: Magnetic sheets are fixed to the end surfaces of the first tooth comb cover plate (6) and the second tooth comb cover plate (7) away from the tooth comb base (1).

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