Surgical operation instrument suitable for taking brains of rats and mice

By designing surgical instruments suitable for brain removal in mice and rats, and using a water cooling system and refrigeration plates to control the temperature of the aluminum plate, the problem of unstable operating environment caused by melting ice was solved, thereby improving the success rate and efficiency of the operation.

CN223438671UActive Publication Date: 2025-10-17NANJING HOSPITAL OF TCM +1
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Patent Information

Application Number
CN202421248476.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-03
Publication Date
2025-10-17
Estimated Expiration
2034-06-03

AI Technical Summary

Technical Problem

In the prior art, brain removal surgery for rats and mice is unstable due to melting ice, which affects the efficiency and success rate of the surgery.

Method used

An operating device consisting of an acrylic water tank, a water cooling radiator, a cooling plate, a fan and a silent water pump was designed. The temperature of the aluminum plate was controlled to maintain surgical stability, and precise operation was performed in combination with a head fixator and an opener.

Benefits of technology

The stable control of temperature during brain harvesting surgery is achieved, which improves the success rate and efficiency of the surgery and avoids failures caused by temperature changes.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a surgical operation instrument suitable for taking brains of rats and mice. Comprising an acrylic water tank, a drainage pipe, a 12V mute water pump, an acrylic plate, a 240-type water cooling row, a fan, a power supply box, a semi-surrounding aluminum alloy fixing frame, a head fixator, a 12706-type refrigeration sheet, an aluminum plate and a mouth gag, wherein the fan is arranged on the 240-type water cooling row; the acrylic plate is arranged on the fan; the acrylic water tank is connected with the 12V mute water pump through a drain pipe and is arranged on the acrylic plate; the power supply box is arranged beside the 240 type water cooling bar; the 12706 type refrigeration sheet is arranged in the center of the aluminum plate; the surface, provided with the 12706 type refrigeration sheet, of the aluminum plate is downwards arranged on the half-surrounded aluminum alloy fixing frame; and the head fixator is arranged on one side surrounded by the semi-surrounded aluminum alloy fixator. The temperature of the aluminum plate is controlled to keep the temperature stable in the brain taking operation.
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Description

TECHNICAL FIELD

[0001] The utility model relates to the field of medical apparatus and instruments, and particularly relates to a surgical operating instrument suitable for brain taking of mice and rats. BACKGROUND

[0002] Brain taking of mice and rats is related to the fields of neurology, pathology and pharmacology. In the research of neurology, mice and rats are often used as model animals to study the pathogenesis, pathological process and treatment method of human nervous system diseases. In order to further explore the problems in these fields, researchers need to conduct detailed structural and functional analysis on the brain of the model animals. In brain taking of mice and rats, brain tissue sampling needs to be kept at low temperature to prevent protein denaturation. At present, the operation is usually performed on ice blocks, but in actual operation, because brain taking needs to take a lot of time, the ice blocks will melt with the change of time, affecting the operation environment during the operation, and when the brain taking operation is too long, the brain taking operation will also fail. SUMMARY

[0003] The utility model discloses a surgical operating instrument suitable for brain taking of mice and rats, which solves the problems in the prior art.

[0004] To achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a surgical operating instrument suitable for brain taking of mice and rats, comprising a acrylic water tank, a first drain pipe, a second drain pipe, a third drain pipe, a 12V mute water pump, an acrylic plate, a 240 type water cooling row, a fan, a power box, a semi-surrounding aluminum alloy fixing frame, a skull fixator, a 12706 type refrigeration sheet, an aluminum plate and an mouth gag, the fan is arranged on the 240 type water cooling row, the acrylic plate is arranged on the fan, the acrylic water tank side surface is connected with the 12V mute water pump through the third drain pipe and is arranged on the acrylic plate, the opposite side surface of the acrylic water tank is connected with the 240 type water cooling row through the first drain pipe, the other water outlet of the 12V mute water pump is connected with the 240 mute water pump through the second drain pipe, the power box is arranged beside the 240 type water cooling row, the 12706 type refrigeration sheet is arranged in the center of the aluminum plate, the aluminum plate is provided with the 12706 type refrigeration sheet on one side, the semi-surrounding aluminum alloy fixing frame is arranged on the aluminum plate, the skull fixator is arranged on one side of the semi-surrounding aluminum alloy fixing frame, the power box is connected with the 12V mute water pump through a power line, the power box is connected with the 12706 type refrigeration sheet through a power line, and the 240 type water cooling row is higher than the plane below the semi-surrounding aluminum alloy fixing frame by 5-8 cm.

[0005] Preferably, the power box is a flashable five-grade power box.

[0006] Preferably, the acrylic plate is partially hollowed out.

[0007] Preferably, the aluminum plate is laid with a non-stick wear-resistant thermal conductive silicone pad, so that the temperature of the aluminum plate is uniform.

[0008] Preferably, the semi-enclosed aluminum alloy fixing frame has a groove on the inner side, and the two long edges of the aluminum plate can be placed in the groove.

[0009] Preferably, the head fixing device is provided with an adjustable nut.

[0010] Preferably, the semi-enclosed aluminum alloy fixing frame is provided with a fixing belt, which further fixes the body of the mouse and prevents the mouse from affecting the operation.

[0011] Preferably, the mouth opener is a water drop-shaped blunt mouth, and the handle is provided with anti-slip patterns.

[0012] Preferably, the power box can be externally connected with a 12V, 8.5A industrial power supply.

[0013] Compared with the prior art, the utility model has the beneficial effects that:

[0014] The utility model discloses a temperature of the aluminum plate is controlled to keep the temperature stable during brain taking operation. BRIEF DESCRIPTION OF DRAWINGS

[0015] Figure 1 It is the whole structure schematic diagram of the utility model.

[0016] Figure 2 It is the side view of the mouth opener of the utility model.

[0017] Label explanation: acrylic water tank - 10, first drain pipe - 20, second drain pipe - 21, third drain pipe - 22, 12V silent water pump - 30, acrylic plate - 40, 240 type water cooling row - 50, fan - 60, power box - 70, semi-enclosed aluminum alloy fixing frame - 80, head fixing device - 90, 12706 type refrigeration piece - 100, aluminum plate - 110, mouth opener - 120. DETAILED DESCRIPTION

[0018] In order to make the personnel in the technical field better understand the scheme of the present application, the technical scheme in the embodiments of the present application will be clearly and completely described below in combination with the drawings in the embodiments of the present application, as follows.

[0019] Please refer to Figure 1 The utility model provides a kind of surgical operating instrument suitable for mouse brain taking, including acrylic water tank 10, first drain pipe 20, second drain pipe 21, third drain pipe 22, 12V silent water pump 30, acrylic plate 40, 240 type water cooling row 50, fan 60, power box 70, semi-enclosed aluminum alloy fixing frame 80, head fixing device 90, 12706 type refrigeration piece 100, aluminum plate 110, mouth opener 120;

[0020] The fan 60 is arranged on the 240-type water cooling row 50; the acrylic plate 40 is arranged above the fan 60; the acrylic water tank 10 and the 12V silent water pump 30 are connected through the third drain pipe 22, the acrylic water tank 10 and the 12V silent water pump 30 are arranged on the acrylic plate 40; the acrylic water tank 10 is connected with the 240-type water cooling row 50 through the first drain pipe 20; the water outlet of the 12V silent water pump 30 is connected with the 240-type water cooling row 50 through the second drain pipe 21; the power box 70 is arranged beside the 240-type water cooling row 50; the 12706-type refrigeration fin 100 is arranged in the center of the aluminum plate 110; the aluminum plate 110 is arranged on the semi-enclosed aluminum alloy fixing frame 80, and one side of the aluminum plate 110 with the 12706-type refrigeration fin 100 is downward; the head fixing device 90 is arranged on one side of the semi-enclosed aluminum alloy fixing frame 80; the power box 70 is electrically connected with the 12V silent water pump 30 through the power line; the power box 70 is connected with the 12706-type refrigeration fin 100 through the power line; the 240-type water cooling row 50 is higher than the plane below the semi-enclosed aluminum alloy fixing frame 80 by 5-8 cm.

[0021] Preferably, the power box 70 is a flashable five-grade power box, which can adjust five gears to ensure the required temperature during operation and keep the temperature stable.

[0022] Preferably, the acrylic plate 40 is partially hollowed out, which can achieve better heat dissipation.

[0023] Preferably, the acrylic plate 40 is 3-5 cm away from the 240-type water cooling row 50, so that better air circulation can be achieved between the two, facilitating heat dissipation.

[0024] Preferably, the power box 70 can be externally connected with a 12V, 8.5A industrial power supply, which can be used for a long time without heating, reducing safety hazards.

[0025] Preferably, the aluminum plate 100 is paved with a non-adhesive wear-resistant heat-conducting silicone pad, so that the temperature of the aluminum plate 100 is uniform.

[0026] Preferably, the semi-enclosed aluminum alloy fixing frame 80 has a groove on the inner side, and the two long edges of the aluminum plate 110 can be placed in the groove, facilitating installation and disassembly.

[0027] Preferably, the head fixing device 90 is provided with an adjustable nut, which facilitates adjustment of the length of the fixing device, so that the head of the mouse can be better fixed.

[0028] Preferably, the semi-enclosed aluminum alloy fixing frame 80 can be provided with a fixing belt, which further fixes the body of the mouse, preventing it from affecting the operation.

[0029] Preferably, the mouth gag 120 is a water droplet-shaped blunt mouth, preventing brain tissue damage during surgery.

[0030] Preferably, the mouth gag handle has anti-slip patterns, preventing slipping when holding.

[0031] In use, the power switch is turned on, one end of the 12706 type refrigeration fin 100 absorbs heat, the other end releases heat, energy transfer is generated to form a temperature difference, thereby achieving the purpose of refrigeration, the released heat is transferred from the heat source to the acrylic water tank 10, the water in the acrylic water tank 10 is circulated in the 240 type water cooling row 50 by the 12V silent water pump 30 to exchange heat, and then the heat is blown out by the fan 60, thereby achieving the purpose of heat dissipation. At this time, the gear can be switched through the power box 70 to ensure that the temperature of the aluminum plate 110 drops until the required temperature is reached. The mouse is placed on the aluminum plate 110 and fixed by the skull fixator 90. After craniotomy, the mouth gag 120 is used to pull, to ensure the complete exposure of the brain tissue and ensure the smooth operation of the operation.

[0032] The above only describes the preferred embodiments of the present application and is not intended to limit the present application. Those skilled in the art can make various changes and modifications to the present application. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.

Claims

1. A surgical instrument suitable for brain removal from mice and rats, characterized by: The invention comprises an acrylic water tank (10), a first drain pipe (20), a second drain pipe (21), a third drain pipe (22), a 12V silent water pump (30), an acrylic plate (40), a 240 type water cooling radiator (50), a fan (60), a power supply box (70), a semi-enclosed aluminum alloy fixing frame (80), a skull fixator (90), a 12706 type cooling plate (100), an aluminum plate (110), and an opener (120), wherein the fan (60) is arranged on the 240 type water cooling radiator (50); the acrylic plate (40) is arranged on the fan (60); the side of the acrylic water tank (10) is connected to the 12V silent water pump (30) by the third drain pipe (22) and is arranged on the acrylic plate (40); the opposite side of the acrylic water tank (10) is connected by the third drain pipe (22). A drainage pipe (20) is connected to the 240 type water cooling row (50); the other water outlet of the 12V silent water pump (30) is connected to the 240 silent water pump (30) by a second drainage pipe (21); the power supply box (70) is arranged next to the 240 type water cooling row (50); the 12706 type refrigeration plate (100) is arranged at the center of the aluminum plate (110); the aluminum plate (110) is provided with the 12706 type refrigeration plate (100) on one side facing downward on the semi-enclosed aluminum alloy fixing frame (80); the skull fixator (90) is arranged on one side surrounded by the semi-enclosed aluminum alloy fixing frame (80); the power supply box (70) is connected to the 12V silent water pump (30) by a power line; the power supply box (70) is connected to the 12706 type refrigeration plate (100) by a power line.

2. A surgical instrument for removing brains from mice and rats as claimed in claim 1, characterized in that: The 240-type water cooling row (50) is 5 to 8 centimeters higher than the lower plane of the semi-enclosed aluminum alloy fixing frame (80).

3. The surgical instrument for removing brains from mice and rats as claimed in claim 1, characterized in that: The acrylic plate (40) is 3 to 5 centimeters away from the 240-type water cooling radiator (50).

4. The surgical instrument for removing brains from mice and rats as claimed in claim 1, characterized in that: The power supply box (70) is a power supply box capable of flashing in five gears.

5. The surgical instrument for removing brains from mice and rats as claimed in claim 1, characterized in that: The acrylic plate (40) is partially hollowed out.

6. The surgical instrument for removing brains from mice and rats as claimed in claim 1, characterized in that: The inner side of the semi-enclosed aluminum alloy fixing frame (80) is provided with a groove, and the two long sides of the aluminum plate (110) can just be placed in the groove.

7. The surgical instrument for removing brains from mice and rats as claimed in claim 1, characterized in that: The skull fixator (90) is equipped with an adjustable nut.

8. The surgical instrument for removing brains from mice and rats as claimed in claim 1, characterized in that: The opener (120) is a teardrop-shaped blunt end.

9. The surgical instrument for removing brains from mice and rats as claimed in claim 1, characterized in that: The handle of the opener (120) is provided with anti-slip grooves.