Brush detection, sampling and collecting equipment for biliopancreatic duct cells
By designing a bile and pancreatic duct cell brush sampling and collection device, combined with negative pressure collection and vacuum suction, the problem of insufficient traditional cell brush sampling has been solved, the diagnosis rate and early diagnosis efficiency of bile and pancreatic malignant tumors have been improved, and more efficient sampling and contrast agent injection operations have been achieved.
Patent Information
- Application Number
- CN202422647984.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-31
- Publication Date
- 2025-10-28
- Estimated Expiration
- 2034-10-31
AI Technical Summary
Conventional cytology brushes have insufficient sampling capacity during endoscopic retrograde cholangiopancreatography, resulting in unsatisfactory sensitivity for the early diagnosis of suspected pancreatic and biliary lesions. Repeated procedures place a burden on patients and the healthcare system, and valuable treatment opportunities may be wasted.
A bile and pancreatic duct cytology brush sampling and collection device was designed, which includes a cytology brush, a handle tube, a negative pressure collection device, a guide wire locking cap, a collection bottle and a tissue collection device. The scraped pathological cells are collected by suction through the negative pressure collection device, and combined with vacuum suction and contrast agent injection operations to improve sampling efficiency.
It improves the diagnostic rate of suspected bile and pancreatic malignancies, increases the chance of capturing a small number of desquamated cancer cells, improves the efficacy of early diagnosis, and enables contrast agent injection after sampling.
Smart Images
Figure CN223473785U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of cell brushing technology, and more specifically, to a device for sampling and collecting bile and pancreatic duct cells by brushing. Background Technology
[0002] Traditional cell brushes mainly consist of an outer tube, a slider, a pull cable, a brush head, and a wristband. The slider connects to the outer tube, the pull cable passes through the slider and the outer tube, the brush head is fixed at the front end of the pull cable, and the wristband is fixed at the rear end of the pull cable. During operation, the brush head is moved back and forth by pulling the wristband, which is suitable for brushing tissue samples under endoscopy. The disadvantages of traditional cell brushes are: simple structure and single function.
[0003] Cell brushing in endoscopic retrograde cholangiopancreatography (ERCP) is the standard method for diagnosing biliary and pancreatic strictures, but its sensitivity is not satisfactory, mainly because traditional cell brushes are not good at collecting tissue cell samples.
[0004] For example, early diagnosis of suspicious biliary and pancreatic lesions relies heavily on adequate cellular brushing during endoscopic retrograde cholangiopancreatography (ERCP). In challenging cases, repeated procedures due to indeterminate pathology can place a significant burden on both patients and the healthcare system. Furthermore, valuable treatment opportunities may be wasted in cases where tissues receive such unsuccessful results.
[0005] The preceding description is intended to provide general background information and does not necessarily constitute prior art. Utility Model Content
[0006] The purpose of this invention is to provide a device for brushing and collecting bile and pancreatic duct cells, which improves the diagnostic rate of suspected malignant tumors of the bile and pancreas.
[0007] This utility model provides a biliary and pancreatic duct cell brush sampling and collection device, including a cell brush, a handle tube, an outer tube, a negative pressure collection device, a guidewire locking cap, a collection bottle, and a tissue collection device. One end of the handle tube is connected to the outer tube, and the other end of the handle tube is connected to the guidewire locking cap. The cell brush includes a pull cable, a brush head, and a handle ring. The brush head is located at the front end of the pull cable, and the handle ring is fixedly located at the rear end of the pull cable. The pull cable passes through the inner cavity of the guidewire locking cap, the handle tube, and the outer tube. The brush head extends out of the outer tube along with the front end of the pull cable, and the handle ring is located at the rear end of the guidewire locking cap. A connector communicating with the inside of the handle tube is provided on the side of the handle tube. The connector is connected to the negative pressure collection device. The tissue collection device is provided between the connector and the negative pressure collection device. A collection bottle is connected to the pipeline between the handle tube and the negative pressure collection device, and a valve is provided on the collection bottle.
[0008] Using the above-mentioned technical solution, the cell brush is fully sampled during endoscopic retrograde cholangiopancreatography (ERCP), and the scraped pathological cells are simultaneously collected by a negative pressure collection device. The simultaneous vacuum aspiration increases the chance of capturing a small number of exfoliated cancer cells. The simultaneous vacuum aspiration during ERCP can improve the diagnostic rate of suspected biliary and pancreatic malignancies, thereby further improving the efficacy of early diagnosis. On the other hand, after the entire cell brush is extracted, contrast agent can be injected through the negative pressure collection device.
[0009] Furthermore, the negative pressure collection device includes a filter and an electric negative pressure aspirator; the inlet end of the filter is connected to the tissue collection device, and the outlet end of the filter is connected to the suction port of the electric negative pressure aspirator; a pressure display screen is provided in front of the electric negative pressure aspirator, a negative pressure adjustment button is provided below the display screen, and an air outlet is provided at the other end of the electric negative pressure aspirator.
[0010] Using the above technical solution, the suction power of the electric negative pressure aspirator is adjusted by the negative pressure adjustment button, and the negative pressure value is displayed on the pressure display screen.
[0011] Furthermore, the tissue collection device includes a front cover, a rear cover, and a filter plate; both the front cover and the rear cover are hollow cylinders, with internal threads on the inner wall of the opening of the front cover and external threads on the outer side of the opening of the rear cover; the filter plate is circular, with a protrusion on the inner wall of the front cover, and the filter plate is placed on the protrusion; when the opening of the rear cover is located at the opening of the front cover, the external threads are screwed onto the internal threads, and the opening end of the rear cover presses against the filter plate.
[0012] Using the above technical solution, when the electric negative pressure aspirator is used, the tissue powder will be blocked inside the front cover by the filter plate; after aspiration, the tissue collection device can be removed, and the front and rear covers can be opened to obtain the collected tissue.
[0013] Furthermore, a developing ring is provided inside the tube hole at the front end of the outer tube. This is suitable for development under X-rays.
[0014] Furthermore, the guide wire locking cap includes a threaded tube, an elastic ring, and a cap; one end of the threaded tube is connected to one end of the handle tube, the elastic ring is located inside the threaded tube, and the cap is provided with an insertion tube, which has a guide wire hole and a cable hole; the cap uses the insertion tube to press the elastic ring against the handle tube end at the bottom of the threaded tube; the outer side of the cap is provided with an internal thread that mates with the threaded tube, and the cable passes through the cap and the elastic ring.
[0015] Using the above technical solution, it is only necessary to rotate the cap. Since the internal thread is fitted onto the external thread of the threaded tube, the entire cap is pressed down, thereby squeezing the elastic ring with the insertion tube. This causes the elastic ring to be compressed axially, and then expands inward on the inside, so that the elastic ring is in close contact with the cable, so as to lock the cable. When it is necessary to release the cable, it is only necessary to turn the cap in the opposite direction to release the pressure on the elastic ring.
[0016] Furthermore, the elastic ring is an elastic silicone ring with a central opening.
[0017] Furthermore, the collection bottle is cylindrical, and scale lines are provided on the side of the collection bottle.
[0018] Furthermore, the collection bottle is made of a transparent material.
[0019] Furthermore, the connection between the collection bottle and the pipe is provided with an arc-shaped bevel.
[0020] Furthermore, the surface of the handle tube is provided with anti-slip texture.
[0021] The bile and pancreatic duct cell brush sampling and collection device provided by this utility model fully samples the cell brush during endoscopic retrograde cholangiopancreatography (ERCP), and simultaneously collects the scraped pathological cells using a negative pressure collection device; the simultaneous vacuum aspiration increases the chance of capturing a small number of exfoliated cancer cells; the simultaneous vacuum aspiration during ERCP can improve the diagnostic rate of suspected bile and pancreatic malignancies, thereby further improving the efficacy of early diagnosis; on the other hand, contrast agent can be injected after the entire cell brush has been extracted. Attached Figure Description
[0022] Figure 1 A schematic diagram of the structure of the bile and pancreatic duct cell brush sampling and collection device provided in this embodiment of the utility model.
[0023] Figure 2 for Figure 1 A schematic diagram of the negative pressure collection device in the pancreatic duct cell brushing sampling and collection equipment.
[0024] Figure 3 for Figure 1 A schematic diagram of the negative pressure collection device of the pancreatic duct cell brushing sampling and collection equipment from another perspective.
[0025] Figure 4 for Figure 1 A schematic diagram of the cross-sectional structure of the collection bottle of the pancreatic duct cell brushing sampling and collection device.
[0026] Figure 5 for Figure 1 A schematic diagram of the disassembled structure of the tissue collection device in the pancreatic duct cell brushing sampling and collection equipment.
[0027] Figure 6 for Figure 1 Another disassembled structural diagram of the tissue collection device of the pancreatic duct cell brushing sampling and collection equipment.
[0028] Figure 7 for Figure 1 A schematic diagram of the cross-sectional structure of the guidewire locking cap of the pancreatic duct cell brush sampling and collection device.
[0029] Figure 8 for Figure 1 A schematic diagram of the cross-sectional structure of the guidewire locking cap and handle tube of the pancreatic duct cell brush sampling and collection device.
[0030] The reference numerals and components involved in the accompanying drawings are shown below:
[0031] 1. Cell brush 11. Pull cord 12. Brush head
[0032] 13. Handle ring 2, Handle tube 21, Connector
[0033] 22. Anti-slip texture; 3. Outer pipe; 4. Negative pressure collection equipment
[0034] 41. Filter; 42. Electric negative pressure suction device; 43. Pressure display screen
[0035] 44. Negative pressure adjustment button; 45. Air outlet; 5. Guide wire locking cap.
[0036] 51. Threaded pipe 52. Elastic ring 53. Cap
[0037] 54. Insertion tube; 55. Guide wire hole; 56. Cable hole
[0038] 6. Collection bottle 61, valve 62, graduation mark
[0039] 63. Curved inclined plane; 7. Tissue collection device; 71. Front end cap.
[0040] 72. Rear end cap; 73. Filter plate; 74. Internal thread.
[0041] 75. External thread; 76. Raised protrusion; 8. Three-way valve Detailed Implementation
[0042] The specific embodiments of this utility model will be described in further detail below with reference to the accompanying drawings and examples. The following examples are used to illustrate this utility model, but are not intended to limit its scope.
[0043] The terms "first," "second," "third," "fourth," etc., used in the specification and claims of this utility model are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence.
[0044] Example 1
[0045] Figure 1 This is a schematic diagram of the structure of the bile and pancreatic duct cell brush sampling and collection device provided in this embodiment of the utility model. Figure 4 for Figure 1 A schematic diagram of the cross-sectional structure of the collection bottle in the pancreatic duct cell brushing sampling and collection device. Please refer to... Figure 1 , Figure 4 The bile and pancreatic duct cell brushing sampling and collection device provided in this embodiment includes a cell brush 1, a handle tube 2, an outer tube 3, a negative pressure collection device 4, a guidewire locking cap 5, a collection bottle 6, and a tissue collection device 7. One end of the handle tube 2 is connected to the outer tube 3, and the other end of the handle tube 2 is connected to the guidewire locking cap 5. The cell brush 1 includes a pull cable 11, a brush head 12, and a handle ring 13. The brush head 12 is located at the front end of the pull cable 11, and the handle ring 13 is fixedly located at the rear end of the pull cable 11. The pull cable 11 is connected to the guidewire locking cap 5, the outer tube 3, the guidewire locking cap 6, and the tissue collection device 7. The handle tube 2 and the outer tube 3 pass through the inner cavity of the handle tube 2 and the outer tube 3. The brush head 12 extends out of the outer tube 3 along with the front end of the pull cable 11. The handle ring 13 is located at the rear end of the guide wire locking cap 5. A connector 21 communicating with the inside of the handle tube 2 is provided on the side of the handle tube 2. The connector 21 is connected to the negative pressure collection device 4. The tissue collection device 7 is provided between the connector 21 and the negative pressure collection device 4. A collection bottle 6 is connected to the pipeline between the handle tube 2 and the negative pressure collection device 4. A valve 61 is also provided on the collection bottle 6.
[0046] It should be noted that during endoscopic retrograde cholangiopancreatography (ERCP), the cell brush 1 thoroughly samples the tissue, while the negative pressure collection device 4 aspirates and collects the scraped pathological cells. Simultaneous vacuum aspiration increases the chance of capturing a small number of exfoliated cancer cells. Vacuum aspiration during ERCP can improve the diagnostic rate of suspected malignant tumors of the biliary and pancreatic tract, thereby further improving the efficacy of early diagnosis. Furthermore, after the entire cell brush 1 is removed, contrast agent injection can be performed. The collection bottle 6 is used to collect the aspirated tissue fluid. Specifically, the connection between the collection bottle 6 and the tubing is provided with an arc-shaped bevel 63 to facilitate the flow of tissue fluid into the collection bottle 6. The collection bottle 6 is cylindrical, with graduation lines 62 on its side. The collection bottle 6 is made of transparent material to facilitate observation of the collected tissue fluid content.
[0047] Figure 2 for Figure 1 A schematic diagram of the negative pressure collection device in the pancreatic duct cell brushing sampling and collection equipment. Figure 3 for Figure 1 A schematic diagram of the negative pressure collection device of the pancreatic duct cell brushing sampling and collection equipment from another perspective. Please refer to... Figure 2 , Figure 3 The negative pressure collection device 4 of this utility model includes a filter 41 and an electric negative pressure aspirator 42; the inlet end of the filter 41 is connected to the tissue collection device 7, and the outlet end of the filter 41 is connected to the suction port of the electric negative pressure aspirator 42; a pressure display screen 43 is provided in front of the electric negative pressure aspirator 42, a negative pressure adjustment button 44 is provided below the display screen 43, and an air outlet 45 is provided at the other end of the electric negative pressure aspirator 42.
[0048] It should be noted that the suction power of the electric negative pressure suction device 42 is adjusted by the negative pressure adjustment button 44, and the negative pressure value is displayed by the pressure display screen 43.
[0049] Figure 5 for Figure 1 A schematic diagram showing the disassembled structure of the tissue collection device in the pancreatic duct cell brushing sampling and collection equipment. Figure 6 for Figure 1 Another disassembled structural diagram of the tissue collection device in the bile duct cell brushing sampling and collection equipment. Please refer to... Figure 5 , Figure 6 The tissue collection device 7 of this utility model includes a front cover 71, a rear cover 72, and a filter plate 73. The front cover 71 and the rear cover 72 are both hollow cylinders. The inner wall of the opening of the front cover 71 is provided with an internal thread 74, and the outer side of the opening of the rear cover 72 is provided with an external thread 75. The filter plate 73 is circular. The inner wall of the front cover 71 is provided with a protrusion 76, and the filter plate 73 is placed on the protrusion 76. When the opening of the rear cover 72 is closed at the opening of the front cover 71, the external thread 75 is screwed onto the internal thread 74, and the opening end of the rear cover 72 presses against the filter plate 73.
[0050] It should be noted that when the electric negative pressure suction device 42 suctions, the tissue powder will be blocked inside the front cover 71 by the filter plate 73; after suction, the tissue collection device 7 is removed, and the front cover 71 and the rear cover 72 are opened to obtain the collected tissue.
[0051] Furthermore, a developing ring is provided inside the tube hole at the front end of the outer tube 3. This is suitable for development under X-rays.
[0052] Figure 7 for Figure 1 A schematic diagram of the cross-sectional structure of the guidewire locking cap in the pancreatic duct cell brush sampling and collection device. Figure 8 for Figure 1 A schematic diagram of the cross-sectional structure of the guidewire locking cap and handle tube of the pancreatic duct cell brush sampling and collection device. Please refer to... Figure 7 , Figure 8 The guide wire locking cap 5 of this utility model includes a threaded tube 51, an elastic ring 52, and a cap 53; one end of the threaded tube 51 is connected to one end of the handle tube 2, the elastic ring 52 is located inside the threaded tube 51, and the cap 53 is provided with an insertion tube 54, which is provided with a guide wire hole 55 and a cable hole 56; the cap 53 uses the insertion tube 54 to press the elastic ring 52 against the end of the handle tube 2 at the bottom of the threaded tube 51; the outer side of the cap 53 is provided with an internal thread that mates with the threaded tube 51, and the cable 11 passes through the cap 53 and the elastic ring 52.
[0053] It should be noted that the elastic ring 52 is an elastic silicone ring with a central opening. By simply rotating the cap 53, the internal thread is fitted onto the external thread of the threaded tube 51, and the entire cap 53 is pressed down, thereby causing the insertion tube 54 to squeeze the elastic ring 52. This compresses the elastic ring 52 axially, causing it to expand inward, thus making the elastic ring 52 in close contact with the cable 11 for locking the cable 11. When it is necessary to release the cable 11, simply turn the cap 53 in the opposite direction to release the pressure on the elastic ring 52.
[0054] Furthermore, the elastic ring 52 of this utility model is an elastic silicone ring with a central opening; anti-slip texture 22 is provided on the surface of the handle tube 2.
[0055] As can be seen from the above description, the advantages of this utility model are:
[0056] 1. The bile and pancreatic duct cell brush sampling and collection device of this utility model fully samples the cells from the cell brush 1 during endoscopic retrograde cholangiopancreatography (ERCP), while simultaneously collecting the scraped pathological cells using a negative pressure collection device 4; the simultaneous vacuum aspiration increases the chance of capturing a few exfoliated cancer cells; the simultaneous vacuum aspiration during ERCP can improve the diagnostic rate of suspected malignant tumors of the bile and pancreas, thereby further improving the efficacy of early diagnosis; on the other hand, contrast agent injection can be performed after the entire cell brush 1 has been extracted.
[0057] 2. The bile and pancreatic duct cell brushing sampling and collection device of this utility model greatly improves the success rate of brushing suspected cancerous tissue, and also greatly improves the success rate of collecting cancerous tissue.
[0058] 3. The bile and pancreatic duct cell brush sampling and collection device of this utility model has a segmented brush head 12 at the front end, which can increase the number of diseased tissue samples brushed and the temporary storage space of tissue cells, thereby increasing the sample capture rate.
[0059] The above description is merely a specific embodiment of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the protection scope of the claims.
Claims
1. A device for brush sampling and collection of bile and pancreatic duct cells, characterized in that, It includes a cell brush (1), a handle tube (2), an outer tube (3), a negative pressure collection device (4), a guide wire locking cap (5), a collection bottle (6), and a tissue collection device (7); One end of the handle tube (2) is connected to the outer tube (3), and the other end of the handle tube (2) is connected to the guide wire locking cap (5); the cell brush (1) includes a pull cable (11), a brush head (12) and a handle ring (13). The brush head (12) is located at the front end of the pull cable (11), and the handle ring (13) is fixedly located at the rear end of the pull cable (11). The pull cable (11) passes through the inner cavity of the guide wire locking cap (5), the handle tube (2) and the outer tube (3). The brush head (12) extends out of the outer tube (3) along with the front end of the pull cable (11). The handle ring (13) is located at the rear end of the guide wire locking cap (5). A connector (21) communicating with the inside of the handle tube (2) is provided on the side of the handle tube (2). The connector (21) is connected to the negative pressure collection device (4). The tissue collection device (7) is provided between the connector (21) and the negative pressure collection device (4). A collection bottle (6) is connected to the pipeline between the handle tube (2) and the negative pressure collection device (4). A valve (61) is also provided on the collection bottle (6).
2. The bile and pancreatic duct cell brushing sampling and collection device according to claim 1, characterized in that, The negative pressure collection device (4) includes a filter (41) and an electric negative pressure suction device (42); The inlet end of the filter (41) is connected to the tissue collection device (7), and the outlet end of the filter (41) is connected to the suction port of the electric negative pressure aspirator (42). A pressure display screen (43) is provided in front of the electric negative pressure suction device (42), a negative pressure adjustment button (44) is provided below the display screen (43), and an air outlet (45) is provided at the other end of the electric negative pressure suction device (42).
3. The bile and pancreatic duct cell brushing sampling and collection device according to claim 1, characterized in that, The tissue collection device (7) includes a front cover (71), a rear cover (72), and a filter plate (73); Both the front cover (71) and the rear cover (72) are hollow cylinders. The inner wall of the opening of the front cover (71) is provided with an internal thread (74), and the outer side of the opening of the rear cover (72) is provided with an external thread (75). The filter plate (73) is circular, and a protrusion (76) is provided on the inner wall of the front end cover (71), and the filter plate (73) is placed on the protrusion (76); When the opening of the rear cover (72) is located at the opening of the front cover (71), the external thread (75) is screwed onto the internal thread (74), and the opening end of the rear cover (72) presses against the filter plate (73).
4. The bile and pancreatic duct cell brushing sampling and collection device according to claim 1, characterized in that, A developing ring is provided in the tube hole at the front end of the outer tube (3).
5. The bile and pancreatic duct cell brushing sampling and collection device according to claim 1, characterized in that, The guide wire locking cap (5) includes a threaded tube (51), an elastic ring (52), and a cap (53); one end of the threaded tube (51) is connected to one end of the handle tube (2), the elastic ring (52) is located inside the threaded tube (51), and the cap (53) is provided with an insertion tube (54), the insertion tube (54) is provided with a guide wire hole (55) and a cable hole (56); the cap (53) uses the insertion tube (54) to press the elastic ring (52) against the end of the handle tube (2) at the bottom of the threaded tube (51); the outer side of the cap (53) is provided with an internal thread that mates with the threaded tube (51), and the cable (11) passes through the cap (53) and the elastic ring (52).
6. The bile and pancreatic duct cell brushing sampling and collection device according to claim 5, characterized in that, The elastic ring (52) is an elastic silicone ring with a central opening.
7. The bile and pancreatic duct cell brushing sampling and collection device according to claim 1, characterized in that, The collection bottle (6) is cylindrical, and scale lines (62) are provided on the side of the collection bottle (6).
8. The bile and pancreatic duct cell brushing sampling and collection device according to claim 7, characterized in that, The collection bottle (6) is made of transparent material.
9. The bile and pancreatic duct cell brushing sampling and collection device according to claim 7, characterized in that, The connection between the collection bottle (6) and the pipe is provided with an arc-shaped bevel (63).
10. The bile and pancreatic duct cell brushing sampling and collection device according to claim 1, characterized in that, The surface of the handle tube (2) is provided with anti-slip texture (22).