Manifold and tray for collecting tissue sample

Abstract

To provide improved tray, manifold, and method for collecting a tissue sample.SOLUTION: Provided are a tray and a manifold for collecting a tissue sample under an action of vacuum. The manifold includes a sleeve. The tray includes a seal member configured to be removably positioned in sealing engagement with the opening. A basket defines a tissue collecting cavity. A base part includes at least one rib arranged within the tissue collecting cavity. The rib defines a plurality of pockets arranged in series in a proximal-to-distal direction so as to provide low pressure regions when the tray is being removed from the sleeve. The rib may be traverse to a longitudinal axis, and / or arcuate in an arc shape complementary to the base part. The base part defines porous features that may be arranged in a plurality of groups. A seal edge seal in sealing engagement with an upper barrier of the sleeve may delay an onset of airflow entering the tissue collecting cavity.SELECTED DRAWING: Figure 10

Description

[Technical Field]

[0001] [Priority claims and related applications] This application is a continuation of U.S. Provisional Application No. 62 / 937,931, filed November 20, 2019. and priority to U.S. Provisional Application No. 63 / 008,026, filed April 10, 2020; The entire contents of each are incorporated herein by reference. This application is a continuation of International Application PCT / US2019 / 032 filed on May 17, 2019. 911, the entire contents of which are incorporated herein by reference.

[0002] The present disclosure is generally directed to devices, systems, and methods for surgical procedures. More specifically, but not exclusively, using a medical waste collection assembly. The present invention is directed to a surgical procedure involving the collection of tissue samples under [Background technology]

[0003] Certain surgical procedures involve the removal of tissue samples for evaluation. A Leapctomy is a procedure that removes tissue from a surgical site within the patient, such as the colon or the endometrial tissue that lines the uterus. This involves removing polyps. Often, polyps are removed using a medical waste collection assembly. Once collected in the suction path, the polysaccharide is drawn out by the suction applied at the surgical site. Recovering these traps is an area of ​​particular interest and development. Summary of the Invention [Problem to be solved by the invention]

[0004] Many known systems and methods are associated with several drawbacks, among them: Increased time and inconvenience during the surgical procedure, potential exposure to hazardous medical waste, multiple tissue samples Therefore, in the industry, the manifold and medical waste disposal Improved manifold and method for collecting tissue samples using a tissue collection assembly - Patents.com Law is needed. [Means for solving the problem]

[0005] A first aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. and a tray configured to collect tissue samples under the action of a vacuum. The tray sealingly engages the opening when the tray is removably positioned within the sleeve. The basket extends from the seal member and is configured to be disposed in the a base portion and an opposing member coupled to the base portion so as to collectively define a tissue collection cavity; The base portion includes a side portion having a tissue collection cavity for collecting a tissue sample. defining (i.e., defining or defining) a plurality of pore features (porosity features) The base portion includes a plurality of ribs disposed within the tissue collection cavity.

[0006] A second aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. and a tray configured to collect tissue samples under the action of a vacuum. The tray sealingly engages the opening when the tray is removably positioned within the sleeve. The basket extends from the seal member and is configured to be disposed in the a base portion and an opposing member coupled to the base portion so as to collectively define a tissue collection cavity; The base portion includes a side portion having a tissue collection cavity for collecting a tissue sample. The base portion extends between the opposed sides and defines a plurality of hole features. It includes ribs that divide the tee into multiple pockets.

[0007] A third aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. and a tray configured to collect tissue samples under the action of a vacuum. The tray sealingly engages the opening when the tray is removably positioned within the sleeve. The basket extends from the seal member and is configured to be disposed in the The basket is elongated and has a length greater than its width. a base portion and opposing sides coupled to the base portion so as to collectively define a tee. The base portion includes a tissue collection cavity and a plurality of hole features for collecting tissue samples. The base portion includes a rib within the tissue collection cavity. The rib is elongated and extends longitudinally. Oriented on an axis transverse to the adaxial axis.

[0008] A fourth aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. and a tray configured to collect tissue samples under the action of a vacuum. The tray sealingly engages the opening when the tray is removably positioned within the sleeve. The basket extends from the seal member and is configured to be disposed in the a base portion and an opposing member coupled to the base portion so as to collectively define a tissue collection cavity; The base portion is defined between an upper surface and an opposing lower surface, and the base portion includes a tray. When the battery is removed from inside the sleeve, it creates a pocket, which is a low pressure area. The rib extends upwardly from the upper surface a distance sufficient to

[0009] A fifth aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. and a tray configured to collect tissue samples under the action of a vacuum. The tray sealingly engages the opening when the tray is removably positioned within the sleeve. The basket includes a seal member configured to be disposed in the basket. a proximal portion extending from the base portion; opposing side portions connected to the proximal portion; and a base portion connected to the opposing side portions. and a distal portion coupled to the base portion and the opposing sides. The base portion and the distal portion collectively define a tissue collection cavity, The ribs, together with the ribs, define a plurality of hole features for collecting tissue samples. At least one conductor is disposed within the collection cavity and arranged in series between the proximal and distal portions. The sleeve defines two pockets that create a low pressure region when the tray is removed from within the sleeve. It is related to the area.

[0010] A sixth aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. and a tray configured to collect tissue samples under the action of a vacuum. The tray sealingly engages the opening when the tray is removably positioned within the sleeve. The basket extends from the seal member and is configured to be disposed in the a base portion and an opposing member coupled to the base portion so as to collectively define a tissue collection cavity; The base portion includes ribs that divide the tissue collection cavity into multiple pockets. The base defines a plurality of hole features in each pocket. Each pocket defines a plurality of hole features. wherein the plurality of hole features are spaced a first distance from one another. The groups are spaced equally apart from each other by a second distance greater than the first distance. are spaced apart from each other.

[0011] A seventh aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. and a tray configured to collect tissue samples under the action of a vacuum. The tray sealingly engages the opening when the tray is removably positioned within the sleeve. The seal member includes a shelf configured to be disposed at the seal member. The member is adapted to be disposed within the sleeve when the member is in sealing engagement with the opening. The basket is complementary in size and shape to the proximal portion extending from the shelf. a proximal portion, opposing side portions coupled to the proximal portion, a base portion coupled to the opposing side portions, and a base portion a distal portion coupled to a proximal portion, an opposing side portion, a base portion, The distal portion and the base portion collectively define a tissue collection cavity, and the distal portion defines a tissue collection cavity. Together they define a plurality of hole features for collecting tissue samples. It is flush with the top surface of the part.

[0012] An eighth aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. and a tray configured to collect tissue samples under the action of a vacuum. The tray sealingly engages the opening when the tray is removably positioned within the sleeve. The seal member includes a shelf configured to be disposed at the seal member. The member is adapted to be disposed within the sleeve when the member is in sealing engagement with the opening. The basket has a proximal portion extending from the shelf portion and a proximal portion extending from the shelf portion. a base portion coupled to the opposing sides; and a base portion and a and a distal portion coupled to the opposing sides. The portions collectively define a tissue collection cavity, and the base portion, together with the tissue collection cavity, The tray begins to be removed from the sleeve, defining a plurality of hole features for collecting fabric samples. When the sleeve is closed, air intrusion into the sleeve is prevented near the proximal part, while the sleeve The proximal portion is at least 5 mm wide so that air ingress is permitted near the base. It extends from the shelf.

[0013] A ninth aspect of the present disclosure provides a device for removably placing a device in a sleeve having an opening. The tray is directed toward the assembly that is drawn in through the first suction path. The tray is configured to collect the fabric sample. a seal member configured to be disposed in sealing engagement with the opening when the seal member is disposed The seal member includes a resiliently flexible portion. The first adjustment member extends from the seal member and the second adjustment member extends from the seal member. The second adjustment member extends from the seal member and is spaced apart from the first adjustment member. The basket extends from the seal member in a direction opposite the first and second adjustment members. The nozzle includes a plurality of nozzles for collecting a tissue sample from the liquid drawn through the first suction path. The first and second adjustment members are disposed on opposite sides of the resilient flexible portion and define a plurality of hole features. Sealed away from the opening to provide a second suction path through the mouth and sleeve. to receive an input for resiliently and pivotably moving at least a portion of the member; It is composed of:

[0014] A tenth aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. The tray is drawn in through the first suction path. The tray is configured to collect tissue samples. a seal member configured to be disposed in sealing engagement with the opening when displaceably positioned The seal member includes an upper region and a lower region. The first adjustment member extends from the upper region. The second adjustment member extends from the lower region and is spaced apart from the first adjustment member. The basket extends from the upper region in a direction opposite the first adjustment member. a plurality of hole features for collecting bubbles, and wherein no portion of the basket is in contact with the sealing member; The first and second adjustment members do not extend from the lower region. and a lower area of ​​the seal member to provide a second suction path through the opening and sleeve. an input to pivot the lower region relative to the upper region to move it away from the opening; is configured to accept

[0015] An eleventh aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. The tray is drawn in through the first suction path. The tray is configured to collect tissue samples. a seal member configured to be disposed in sealing engagement with the opening when displaceably positioned The seal members are separated by a living hinge including a thinned portion of the seal member. The basket includes a lower region and a lower region. The adjustment member extends from the upper region. The basket extends from the seal member in a pair of directions. The adjustment member includes a hole feature configured to provide a second suction path through the opening and the sleeve. a living hinge around which a lower region of the sealing member is moved away from the opening; It is configured to receive an input to pivot the lower region relative to the upper region.

[0016] A twelfth aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. The tray is drawn in under the action of suction (vacuum). The tray is configured to collect tissue samples. a seal member configured to be disposed in sealing engagement with the opening when displaceably positioned The adjustment member extends from the seal member. The basket is coupled to the seal member and includes a a base portion, opposing sides joined to the base portion so as to collectively define a tissue collection cavity; and a plurality of hole features defined in the base portion for collecting tissue samples. The basket has a base, opposing sides, and an upper aspect of the opposing sides. The basket has a first cross-sectional profile defined by a boundary of the adjustment member and The seal member further includes a neck region extending in an opposite direction from the seal member. a second transition surface defined between the lower transition surface of the A void space is formed between the tissue-collecting cavity and the seal member. As defined, the second cross-sectional profile is smaller than the first cross-sectional profile.

[0017] A thirteenth aspect of the present disclosure is a device for removably placing a device in a sleeve having an opening. The tray is drawn in through the first suction path. The tray is configured to collect tissue samples. a seal member configured to be disposed in sealing engagement with the opening when displaceably positioned The seal member includes a resiliently flexible portion. The adjustment member extends from the seal member and contacts the opening and and a second suction path through the sleeve and away from the opening. configured to receive an input to resiliently and pivotally move at least a portion thereof; The basket is coupled to the seal member and collectively defines a tissue collection cavity. Thus, the device comprises a base portion, opposing sides coupled to the base portion, and a support for collecting tissue samples. a plurality of hole features in the base for receiving the tissue and a plurality of hole features along the base in a direction away from the tissue collection cavity; and a leg including a plurality of opposed rails extending therefrom. The leg is configured to pass the second suction path therethrough. Constructed (to form).

[0018] In some embodiments, the tray has at least two pockets, for example, four pockets. One of the pockets may be between the rib and the proximal portion, and / or Alternatively, the basket may be defined between the rib and the distal portion. The socket may be elongated and have a length greater than its width so that it has a longitudinal axis. The ribs may be elongated and oriented along an axis transverse to the longitudinal axis. The plurality of hole features may be disposed between the ribs. There may be three ribs, which may be spaced equally apart from one another. More specifically, the three ribs define four pockets in the base portion. and a plurality of hole features are located within each of the four pockets. The base portion may be arcuate in shape and the opposing sides may be parallel to one another. The rib may be arcuate, and the arcuate shape of the base portion may be concave between the rib and the base portion. The plurality of hole features may be contoured to be complementary to the shape of the at least two hole features. Each of the groups may be arranged in a longitudinal direction along the base portion. The plurality of ribs may include at least two rows of the holes oriented in the hand direction. The above embodiment can be applied to any of the first to thirteenth embodiments of the tray. It may be included in one or more of them.

[0019] A fourteenth aspect of the present disclosure provides a manifold for collecting tissue samples through a suction tube. The manifold includes a housing having a sleeve defining an opening. The sleeve includes an inlet fitting that defines an inlet bore opening into the sleeve. The manifold includes a tray. The tray is any one of the first to thirteenth aspects of the tray. It can be any one or more.

[0020] A fourteenth aspect of the present disclosure provides a medical waste collection assembly including a receiver, the medical waste collection assembly including a receiver under vacuum. The present invention is directed to a method for collecting a sample by using a suction tube. The manifold is coupled to the inlet fitting of the receiver. The manifold is disposed within the opening of the receiver. (i) a sealing member of the tray is disposed in sealing engagement with the opening; and (ii) a distal portion of the tray is disposed in sealing engagement with the opening. (iii) the tissue collection cavity of the tray is positioned distal to the entrance bore; The medical waste is removably disposed within the sleeve in the first position so as to be open. The waste collection assembly is in a first position and works with the tray, and the sample is directed through a first aspiration path. The input moves the first and second adjustment members relative to one another. The first and second adjustment members are provided with a spring to allow the adjustment members to resiliently move toward the sealing member. The lower portion moves away from the opening to provide a second suction path. the input to the adjustment member is maintained while moving the tray from the first position to the second position; At this time, the sealing member moves away from the opening, and the sealing edge of the tray The distal portion of the tray remains in sealing engagement with the upper barrier that defines the second position. The first and second adjustment members remain positioned distal to the inlet bore in this position. The seal member is maintained in the open position while the valve is moved from the second position to the third position. The tray seal edge is moved further away from the mouth to provide a third suction path. Disengage the upper barrier that defines the sleeve. The distal portion of the tray is then disengaged, eliminating the first suction path. The nozzle is moved to a third position proximal to the inlet bore to provide a fourth suction path.

[0021] Benefits of the present disclosure may be obtained by reference to the following detailed description when considered in conjunction with the accompanying drawings. Thus, it will be readily understood when the present disclosure is better understood. [Brief explanation of the drawings]

[0022] [Figure 1] FIG. [Figure 2]FIG. 10 is a perspective view of the manifold with the tray removed from the sleeve. [Figure 3] FIG. 10 is a near-front elevation view of the manifold without the tray showing the internal features of the sleeve. [Figure 4] FIG. [Figure 5] FIG. [Figure 6] FIG. [Figure 7] FIG. 1 is a cross-sectional view of a manifold including a tray disposed within a sleeve, the tray being in a sealing configuration. [Figure 8] FIG. 1 is a cross-sectional view of a manifold including a tray disposed within a sleeve, the tray being in a bleed configuration. [Figure 9] FIG. [Figure 10] FIG. 10 is a top front perspective view of the tray of FIG. [Figure 11] FIG. 10 is a top plan view of the tray of FIG. 9. [Figure 12] 1 is a cross-sectional view of a portion of a manifold with a tray disposed within a sleeve in a first position and in a sealed configuration. [Figure 13] 1 is a cross-sectional view of a portion of the manifold with the tray disposed within 14 in a second position. [Figure 14] FIG. 10 is a cross-sectional view of a portion of a manifold with a tray disposed within a sleeve in a second position. [Figure 15] FIG. 15 is a detailed view of the portion of the manifold within detail 15-15 in FIG. DETAILED DESCRIPTION OF THE INVENTION

[0023] The extraction (aspiration) of tissue samples from within the patient is performed using a medical waste collection assembly, e.g. Manufactured by and jointly owned by Stryker Corporation (Kalamazoo, Michigan) Patent Nos. 7,621,898, 8,216,199, 8,740,866, Nos. 8,915,897, 9,579,428, and 9,782,524 (each of which Neptune 2 (registered trademark) disclosed in US Pat. No. 6,299,499, the entire contents of which are incorporated herein by reference. and can be facilitated with the Neptune 3® waste management system The medical waste collection assembly, in its broadest sense, is a device in fluid communication with the proximal end of the suction tube. The distal end of the suction tube includes a vacuum pump adapted to be placed in a closed position at the surgical site. As used herein, proximal refers to a device that is connected to a manifold. When engaged with the manifold 100, the rear of the manifold 100 and the medical waste collection assembly distal refers to the direction toward the front of the manifold 100 and the surgical site. (See Figure 1). The desired tissue sample is excised, for example, using a snare technique. The tissue sample is drawn into a suction tube toward a medical waste collection assembly.

[0024] The suction of semi-solid and solid materials, including tissue samples, is performed using the medical waste collection assembly. must be captured or appropriately filtered to avoid potential clogging of the components. The medical waste collection assembly is adapted to be removably engaged with the manifold 100. The medical waste collection assembly includes a manifold receiver. When the manifold 100 is engaged with the manifold receiver, the outlet opening of the manifold 100 and the fluid In one embodiment, the common owned rice National Patent No. 7,615,037, No. 8,518,002, No. 8,915,897, and and 9,579,428, the entire contents of each of which are incorporated herein by reference. As disclosed in the publication, the manifold receiver has an outlet opening that engages a boss that defines a bore. When rotated together, the bore can be rotated to align with the suction inlet. In another embodiment, the manifold receiver may include a valve body having a valve element of 2019. Co-owned U.S. Patent No. 10,471,188, issued November 12, 2003 (including The entire assembly is translatable as disclosed in The inlet mechanism may include a suction fitting configured to engage the outlet opening. The manifold 100 is adapted to receive a suction tube, thereby A suction path is established from the suction tube to the medical waste collection assembly through the manifold 100. Among other functions, the manifold 100 is used to aspirate blood from the surgical site. It captures semi-solids and solids entrained in the stream.

[0025] 1 and 2 show an embodiment of a manifold 100 for collecting tissue samples. The manifold 100 is adapted to be removably engaged with a manifold receiver. The housing 102 includes a main body (body) 104 and a cap. The manifold 100 may include a manifold volume (manifold volume). a manifold volume 108 and an outlet port in fluid communication with the manifold volume 108; A seal 110 may be coupled to the housing 102 and may define a mouth 109. The manifold body 104 can be sized to cover the port opening 109. The volume 108 may be defined by the body 104 and / or the cap portion 106, In some embodiments, the housing 102 may be an adapter for a suction tube. The body 104 may not define a manifold volume 108. a manifold receiver of the manifold assembly, the manifold receiver including a feature configured to engage a complementary feature of the manifold receiver of the manifold assembly; This is explained in more detail in the aforementioned U.S. Patent No. 10,471,188. The features of the housing 102 that are included include arms 116, locking elements 117, and a spine. The body 104 may include a catch 118, and / or a catch 119. The body 104 defines a gap 130. The first leg 126 and the second leg 126 are spaced apart from each other so as to fit together. The legs 128 may be included.

[0026] The housing 102 includes at least one inlet fitting adapted to receive a suction tube. The inlet fittings 112a, 112b include a manifold volume The valve 132 defines respective inlet bores 114a, 114b in fluid communication with the valve 132. , coupled to the housing 102 to prevent backflow from the manifold volume 108. The valve 132 can be coupled to the cap portion 106. In particular, the inner or proximal surface of the cap portion 106 may include a connecting portion such as a proximally extending protrusion. The valve 132 may be configured to be axially spaced from the connector 107 of the cap portion 106. A complementary coupler 137 is included. The coupler 137 is sized to engage the protrusion in an interference fit configuration. Additionally or alternatively, suitable fasteners such as adhesives, mechanical fasteners, etc. A bonding process can be used to join the valve 132 with the cap portion 106 . The valve 132 may include a pair of flappers 135, one of which may be Establishing communication between the accessory sleeve 113 and the manifold volume 108 The transfer bore 125 is configured to selectively cover the other flange. The valve 135 is configured to selectively cover the second one of the inlet bores 114b. 132 is moved in a proximal-to-distal direction under vacuum provided by a vacuum pump. The valve 13 may be made of an elastic material so as to be elastically deformable in the direction (direction). Some features of the present invention are disclosed in U.S. Patent No. 7,715,025, issued November 10, 2009. 37, the entire contents of which are incorporated herein by reference. The seals at the proximal ends of the inlet and transfer bores 114b, 125 are from the ring volume 108 to the accessory sleeve 113 and the inlet bore 114b, respectively. Prevents backflow and therefore possible spillage of waste materials.

[0027] The manifold 100 includes a filter element disposed within the housing 102 and within the suction path. 133. The filter element 133, in its broadest sense, is a filter element for medical waste collection. Liquid drawn through manifold 100 under the influence of the vacuum provided by the system configured to capture or collect semi-solid or solid waste material entrained within the waste material. The filter element 133 includes a plurality of pore features (porous features) or Apertures include, for example, holes, holes, and / or slots, among others. In this case, the suction path extends from the inlet bores 114a, 114b to the manifold volume 108, The filter element 133 and the outlet opening 109 are each provided to the suction inlet of the receiver. The filter element 133 can form a basket-like structure. The element 133 may be disposed within the manifold volume or may be disposed within the manifold volume 1. 08. The shape and configuration of the filter element 133 suitable for certain embodiments is a commonly owned 201 International Publication WO2018 / 170233 filed on March 15, 2018, and November 2019 The patents are disclosed in the international publication PCT / US2019 / 060732 filed on the 11th, The entire contents of which are incorporated herein by reference. Furthermore, the filter element 133 may comprise: It can be considered optional, and manifold designs are contemplated that do not include the filter element 133. can be.

[0028] 1 and 2, the cap portion 106 includes a cap head 142 and a cap cap 142. The cap head 142 includes a support frame 143 disposed distally of the support frame 143. 3 may be removably coupled to the cap faceplate 140 of the cap head 142, Alternatively, it may be formed integrally with the cap face plate 140 of the cap head 142. 06 includes an accessory sleeve 113, a first inlet fitting 112a, and a second inlet fitting More specifically, the accessory sleeve 113 further includes a support frame 143. The first inlet fitting 112a extends upward from the upper barrier 103. The first inlet bore 114a may extend through the upper barrier 103. The second inlet fitting 112b extends distally from the cap faceplate 140 and (as described herein) The second inlet bore 114b (also referred to herein as a bypass bore) is connected to the cap faceplate 140. The housing 102 of the manifold 100 extends through the accessory sleeve 113. It further defines an accessory opening 111 opening therein. As best shown in FIG. The accessory sleeve 113 is connected to the upper barrier 103, the lower barrier 122, and the upper barrier 1 122 and a plurality of opposed side barriers 123 extending between the The accessory sleeve 113 can be partially defined as an accessory opening. It may be further defined by an end barrier 124 opposite the mouth 111. The accessory sleeve 113 extends through the transfer bore 125 and the cap face plate 140. The manifold volume 108 is in fluid communication with the manifold volume 108 through the extending aperture 158. More specifically, the transfer bore 125 is formed between the lower barrier 122 and the side barrier 123. and a first end of at least one of the manifold volumes, e.g., aperture 15. The accessory sleeve 113 is defined between the first end and the second end that opens into the second end of the accessory sleeve 113. Positioning features 145 that define troughs 127 to be formed, and orientation features 18 It can contain 9.

[0029] The manifold 100 has an accessory opening 111 and a second inlet bore 114. The first cover 151a and the second cover 151b are configured to selectively cover the first and second covers 151a and 151b. 1 to 3, the first cover 151a has an accessory opening. The first cover 151a is molded to the contours of the 111. The first cover 151a is attached using a hinge or tether 149a. The first cover 151a can be coupled to the housing 102 by The first cover can be coupled to an accessory sleeve 113 near its distal end. 151a selectively positions the first cover 151a over the accessory opening 111 The first camera may include a grip configured to be manipulated by a user. Bar 151a is configured to engage accessory opening 111 with an interference fit engagement. The first cover 151a may include an inner seal rim formed therein. 11, the manifold 100 is coupled to a first inlet fitting 112a. The medical waste collection apparatus is connected to the first inlet bore 114a to provide a suction path from the suction tube through the first inlet bore 114a. In such a configuration, the tray 176 may be operable with the accessory assembly. The first cover 151a cannot be removably disposed within the sleeve 113. Maintain suction (vacuum) through the nifold 100. During operation of the medical waste collection assembly Disengaging the first cover 151a from the accessory opening 111 allows the medical waste Suction can be effectively interrupted without having to terminate operation of the collection assembly. The cover 151b may be coupled to the housing 102 using a tether 149b. In the example where the second inlet fitting 112 is not utilized, the second cover 151b is A friction or interference fit with the second inlet fitting 112b to selectively cover the bore 114b. The size is adjusted by combining the pieces.

[0030] The manifold 100 is adapted to be removably disposed within an accessory sleeve 113. The tray 176 includes the aforementioned tray 176 configured with a tissue collection cavity 182. a basket 180 defining a tissue collection cavity 182; and a plurality of pore features (porosity) within the tissue collection cavity 182. When the tray 176 is placed in the accessory sleeve 113, A plurality of hole features 186 are located in the suction path for collecting tissue samples. 76 is inserted into the accessory opening 11 when the tray 176 is in the accessory sleeve 113. The seal member 154 is adapted to be in sealing engagement with the nozzle 1. , a shelf 155, and a flange 156. The shelf 155 is 56 and is sized to be slightly smaller than accessory opening 111. Similarly, the outer periphery of the flange portion 156 is formed with respect to the accessory opening 111. Specifically, the accessory openings 111 are formed on the upper surface, the lower surface, and the opposing When collectively defined by the side barriers 103, 122, 123, the perimeter is and the adjacent edges of each of the barriers 103, 122, 123. The shelf 155 facilitates placement of the tray 176 within the accessory sleeve 113. This helps prevent loss of suction through the accessory opening 111. 156 defines a sealing surface 157, which is located around the periphery of the accessory opening 111. The tray 176 is in the accessory sleeve 113 and When sealing surface 157 contacts accessory sleeve 113, suction is applied to the medical waste collection accessory. The suction is maintained through the suction path during assembly operation.

[0031] The seal member 154 includes a resilient flexible portion 160. The flexible portion 160 is configured to have a spring, as will be further described. The seal is positioned away from the accessory opening 111 to provide a second suction path. The member 154 is configured to resiliently and pivotally move at least a portion of the member 154 . As shown in FIG. 6, the seal member 154 includes an upper region 170 and a lower region 172. In some configurations, the flexible section 160 may have a small gap between the upper and lower regions 170 and 172. In one example, the flexible portion 160 is disposed at least partially at the thinned portion ( A living hinge (a living hinge with a reduced thickness portion) ) 174, and the lower region 172 is connected to the upper region 170 about the living hinge 174. The frame is designed to be pivotable.

[0032] 4-6, basket 180 is extended distally from seal member 154. The basket 180 has a base portion 184 and a support portion 185 connected to the base portion 184. The base portion 184 includes a side portion 185 (also referred to herein as a side portion) that is joined to the base portion 184. As shown, the shape is arcuate and may be concave between the opposing sides 185, although alternatives may be used. The base and sides may be flat or of any suitable profile. 184, 185 extend from the seal member 154 and define a tissue collection cavity 182. Conventionally, the tissue collection cavity 182 can be positioned at the side 185 The hole feature is considered to open away from the base 184 in a direction parallel to the hole. A plurality of hole features 186 are defined within the base portion 184. The hole features 186 are formed on opposing side portions 181. 85. Further, the basket 180 may be defined on the opposing side 18 5 and may include a distal portion 190 that further defines a tissue collection cavity 182. The distal portion 190 can include multiple hole features 186. The number of hole features 186 is optional.

[0033] The tray 176 includes first and second adjustment sections adapted to accept input from a user. The first and second adjustment members 188a, 188b are baskets. The second adjustment member 188b extends from the seal member 154 in a second direction opposite the port 180. The first and second adjustment members 188a, 188b are grips that are held between the fingers of a user. The first adjustment member 188a may be configured to be spaced apart from the first adjustment member 188a. Typically, the gripping portion rotates the first adjustment member 188b toward the second adjustment member 188b for the functions described. The member 188a can be positioned to be grasped by a user to move the member 188a. be.

[0034] Referring to FIG. 6, the first adjustment member 188a extends from the upper region 170 of the seal member 154 to the The second adjustment member 188b extends from the lower region 170 of the seal member 154. In such a configuration, the first and second adjustment members 188a, 188b , can be disposed on the opposite side of the flexible portion 160 of the seal member 154. For example, 6 are first and second adjustment members 188a, 188b disposed on opposite sides of the living hinge 174. As a result, the first and second adjustment members 188a, 188b are positioned between the user's fingers. When pinched between the second adjustment member 188b, the second adjustment member 188b contacts the sealing surface 157 of the sealing member 154. It can be moved towards the first adjustment member 188a with a corresponding movement.

[0035] The configuration of the basket 180 may be such that (e.g., the first adjustment member 188b is moved toward the second adjustment member 188b) The first adjustment member 188a remains substantially stationary while the second adjustment member 188b (as opposed to the first adjustment member 188b) 188a, and is further configured to assist in the movement of the second adjustment member 188b toward the second adjustment member 188a, and thus Pivoting the lower region 172 of the seal member 154 away from the accessory opening 111 In particular, the basket 180 extends from the upper region 170 and any part of the basket 180 No portion extends from the lower region 172. The basket 180 is attached to the accessory sleeve 11. 3, the first and second flexible portions 160 can be positioned in a proper manner. By pinching the adjustment members 188a, 188a, the adjustment members 188a can be moved away from the accessory opening 111. This results in pivoting of the lower region 172 of the seal member 154 (see FIG. 8). The tissue collection cavity is larger than the height of the upper region 170 (close to the height of the basket 180). To accommodate the above-described configuration, the basket 180 is A void space 194 is defined between the cavity 182 and the lower region 172 of the seal member 154. The neck region 192 may include a neck region 192 having a reduced cross-sectional profile such that the In other words, the main portion of the basket 180 is (transverse to the longitudinal axis of the tray 176) The neck region 172 has a first cross-sectional profile (in a plane defined by the first cross-sectional profile). The first cross-sectional profile has a second cross-sectional profile that is smaller than the base. portion 184 and the opposing side portion 185 (and the boundary extending between the upper surfaces of the opposing side portions 185) The second cross-sectional profile can be defined by the lower portion of the neck region 192. The side connecting surface 196 and the opposing side 185 (and the upper surface of the opposing side 185) As a result, the bus The interface between the socket 180 and the seal member 154 is in the upper region 170. 96 and wall 198 are spaced apart so that the depth of the tissue collection cavity 182 is maximized overall. The tilt angle can be tilted downward in the vertical direction.

[0036] The tray 176 extends from a base portion 184 and, more particularly, a tissue collection cavity 182 and The base 184 may include legs 131 extending in opposite directions from the base 184. The base portion 184 is generally U-shaped and bounds a plurality of hole features 186 when viewed from the bottom. In some embodiments, the legs 131 may extend from the base near the sides 185. 4-6 show a plurality of opposed rails 136 extending from the portion 184. The rails 136 are shown facing each other with slots 138. 31 is illustrated when the tray 176 is fully positioned within the accessory sleeve 113. and a second suction path through the manifold volume 108. It will be appreciated that the axial length also defines the boundary of the bore 125 .

[0037] 1 and 2, the tray 176 is only one-way relative to the upper barrier 103. In particular, the tissue collection cavity 182 opens toward the upper barrier 103. , the accessory sleeve 113 is inserted into the accessory sleeve 113 so as to place the tray 176 therein. Including an orientation feature 187 configured to engage three orientation features 189. Orientation features 189 of accessory sleeve 113 allow the opposing side barriers 123. In other words, each side near the upper barrier 103 The face barrier 123 flares outward to define the groove. The feature 187 extends outward from the side 185, particularly near the top surface of the tray 176. Complementary orientation features 187, 189 allow the rails to slide within the grooves. The connector can be configured to be movably engaged by a fastener.

[0038] 7 and 8, the tray 176 is removed into the accessory sleeve 113. When the seal member 154 is removably disposed, (i) the seal member 154 seals the accessory opening 111. (ii) tissue collection cavity 182 is disposed within accessory sleeve 113; , open toward the inlet bore 112a; and (iii) the base portion 184 and / or the side portion 185 The tray 176 is attached to the lower barrier 122 so as to provide a gap G between the base 184 of the tray 176 and the lower barrier 122. 113. In such a configuration, the accessory sleeve 113 engages with a locating feature 145. During operation of the medical waste collection assembly, the first suction path FSP is connected to the suction tube, the inlet bore 11 4a, tissue collection cavity 182, through transfer bore 125, and through exit opening 1 The first suction path is then passed through the manifold volume 108, which then passes through the manifold volume 108. The moving tissue samples are collected in tray 176 .

[0039] The presence of wall 198, e.g., a sloped surface, allows the collected tissue sample to pass through seal member 15. 4. Furthermore, as mentioned above, , as shown in FIGS. 1 and 2, the upper barrier 103 can be transparent. As a result, a user looking at the manifold 100 from above, although typical based on the operating height of the manifold 100 when coupled to the medical waste collection assembly, can quickly confirm whether a tissue sample has been collected and / or the quality of the collected tissue sample. In contrast, when there is no wall 198 to separate and settle the collected tissue sample from the seal member 154, the user needs to approach the manifold 100 to determine whether a tissue sample has been collected. And, of course, when there is no transparent upper barrier 103, the user needs to at least partially remove (remove) the tray 176 from the manifold 100 to determine whether a tissue sample has been collected.

[0040] The base portion 184 of the tray 176 may be arranged to be placed on the shelf portion of the shelf portion 147 so that the gap G is defined between the lower surface of the base portion 184 of the tray 176 and the upper surface of the valley 127, [[ID=2l]] or may be supported by the shelf portion 147 in other ways. The gap G can be considered to be below the tray 176 (i.e., on the opposite side of the tissue collection cavity 182 in the aforementioned convention). When the tray 176 is disposed within the accessory sleeve 113, the gap G communicates with the transfer bore 125 extending into the manifold volume 108. The orientation feature 187 of the tray 176 can further serve as an orientation feature for determining the vertical position of the base portion 184 relative to the lower barrier 122, and thus at least partially affect the size of the gap G. The upper surface of the tray l76 is slightly between the upper barrier 103 ​​​​​​​​​​​​It is further noted that the upper barrier 103 is positioned adjacent to the upper barrier 103 at a suitable distance.

[0041] When it is desired to retrieve the collected tissue sample, the tray 176 is inserted into the tissue collection container. Slidable from accessory sleeve 113 with tissue sample disposed within cavity 182 In known systems, the tissue specimen is removed (dismounted) by the fluid flow. tissue samples may be exposed to undesirable shocks (and associated forces). Instead, they may be swept along with the fluid flow and ejected from the tray. The manifold 100 of the present disclosure provides a method for detecting imperfections in tissue samples. By creating a second suction path SSP that is provided in such a way that the possibility of loss of For example, the gap G described above provides a second suction path to the tray 1. 76. Furthermore, the manifold 100 is configured to allow the first suction path to be temporarily restricted. It is advantageous to provide a second suction path of sufficient volume flow so that the second suction path can be added or eliminated. In other words, the manifold 100 is configured to allow the medical waste collection assembly to without the need to remove the drive 100 and / or deactivate the medical waste collection assembly. It is not necessary, perhaps temporarily, to reduce suction through the first suction path or It is advantageous to bring about "bleeding."

[0042] In operation, if the user desires to reduce or eliminate the first suction path: A user provides input to the first and second adjustment members 188a, 188b. The user can grasp the first and second adjustment members 188a, 188b. With particular reference to the first adjustment member 188a, the second adjustment member 188b moves or Pivot (P) to move manifold 100 from the sealing configuration to the bleed configuration. The movement of the second adjustment member 188b causes at least a portion of the seal member 154 to contact the lower burr. It will move away from a portion of the accessory opening 111 near the opening 122. For example, the lower region 172 of the seal member 154 is pivoted to move the lower region 172 away from the accessory opening 111; This pivot provides a second aspiration path SSP without disturbing the collected tissue sample. The hinge 174 may be centered.

[0043] The valley 127 extending to the accessory opening 111 is exposed to the atmosphere and provides a second suction path SSP. The gap G can be at least partially defined by a valley 127, and the second suction The drag path SSP encounters the tissue collection cavity 182 of the tray 176 due to fluid dynamics. The second beam is directed through the gap G without being directed toward it. The suction path SSP defines the base portion 184 of the tray 176 and the accessory sleeve 113. The accessory is inserted through a gap G between the lower barrier 122 of the housing and the accessory opening 111. Further, the legs 131 are provided with a second suction port toward the transfer bore 125. The rail 136 has a slot 138 through which the second suction path SSP passes. For example, legs 131 provide flow characteristics when manifold 100 is in the bleed configuration. When the second suction path SSP and the first suction path FSP are in a state where the difference in resistance between the first suction path FSP and the second suction path SSP is large, bleed configuration, thereby allowing the secondary suction path SSP to function as the primary suction path in the bleed configuration. The size of the gap G is such that negligible suction is maintained through the suction tube. (i.e., the distance from the base 184 to the lower barrier 122 defining the valley 127) This increases the effectiveness of the bleed function and also allows for the removal of collected tissue samples. The possibility of fluid flow in the second suction path SSP above the tray 176 that may be broken or ejected. This is understood to further reduce sexual activity.

[0044] A second suction path SSP to the end of the suction tube located significantly upstream at the surgical site. The resistance of the fluid (e.g., air) to entering the suction tube (as well as the density of the waste material in the suction tube relative to the air) ) is smaller, the fluid dynamics are such that the second suction path SSP is in the bleed configuration. Become the primary suction pathway, determining that negligible suction can be maintained through the suction tube The user immediately restores the primary aspiration pathway FSP as the primary (and only) aspiration pathway. If desired, the user may apply pressure to the first and / or second adjustment members 188a, 188b. The force applied to the seal member 154 is simply released. The second suction path SSP adjacent to the accessory opening 111 allows the seal member 154 to This results in the manifold 100 regaining its seal configuration. The manifold 100 can be transferred between lead configurations without undue difficulty and for medical disposal. This can be done as many times as necessary without having to stop the operation of the object collection assembly.

[0045] Also, as mentioned, the second suction path SSP is located below the tray 176 (i.e., in front of the tray 176). (opposite the tissue collection cavity 182 in the previously described practice). If the user desires to retrieve the tissue sample collected in tissue collection cavity 182, In this case, the user may remove the first and second trays 176 from the accessory sleeve 113. The gap G is adjacent to the upper barrier 103. 176. Therefore, the distance between the upper surfaces of the trays 176 is relatively large. When tray 176 is removed, substantially the entire second suction path SSP remains below tray 176. The tissue collection cavity 182 is then moved upward to allow the tray 176 to be drawn into the cavity. It is understood that the fluid flow in the moving second suction path SSP is reduced. Users can now use Tray 176 with more confidence without the risk of unintentionally losing collected tissue samples. It can be removed by

[0046] Collected tissue samples during removal of tray 176 from accessory sleeve 113 Sudden loss of pull is further minimized by a plurality of ribs 200 disposed within the basket 180. Next, referring to FIGS. 9 to 15, the tray can be made smaller than the embodiment described above. 176 is shown using the same numbers to indicate the same components and any parts that are not repeated multiple times. The intended embodiments are for the sake of brevity and should not be considered limiting.

[0047] The tray 176 includes a basket 180 defining a tissue collection cavity 182 and a tissue collection cavity 184. and a plurality of hole features 186 within the cavity 182. The tray 176 is When in accessory sleeve 113, it is in sealing engagement with accessory opening 111. The seal member 154 is configured to close the second suction path. At least one portion of the seal member 154 is spaced from the accessory opening 111 to provide The flexible portion 160 is configured to resiliently and pivotally move the flexible portion. The portion 160 is configured to facilitate pivoting of the lower region 172 relative to the upper region 170. The first and second adjustment members 188a, 188b may be a locking hinge 174. When held between the fingers, the first seal member 154 is moved with corresponding movement of the sealing surface 157 of the sealing member 154. The second adjustment member 188b can be moved toward the adjustment member 188a. The tissue collection cavity 182 is spaced apart from the lower region 172 of the seal member 154. A neck region 192 may be included to define a void space 194 .

[0048] The basket 180 has a base 184 and is arranged to define a tissue collection cavity 182. and a plurality of opposed sides 185 (also referred to herein as sides). A hole feature 186 is defined in the base portion 184. The plurality of hole features 186 are arranged in opposed It is contemplated that the basket 180 may be defined within the side 185. Further, the basket 180 may be defined within the opposite side The tissue collection cavity 182 includes a distal portion 190 extending between the distal end portions 185 and further defining the tissue collection cavity 182. The tray 176 can be mounted on legs 131 extending from a base 184, e.g., side portions 185. The rails 136 may include a plurality of opposed rails 136 extending from the base 184 near the The oriented rail 136 may have a slot 138 .

[0049] When the tray 176 is removably disposed within the accessory sleeve 113, the gap G is located between the base 184 of the tray 176 and the lower barrier 122, and forms a first suction path F The SP includes a suction tube, an inlet bore 114a, a tissue collection cavity 182, a transfer bore 12 5 and into a manifold volume 108 leading to an outlet opening 109 The tissue sample moving through the first suction path is When it is desired to retrieve the collected tissue sample, the tray 176 The tissue sample is then extracted from the accessory sleeve 113 along with the tissue sample disposed within the tissue collection cavity 182. As previously detailed, manifold 100 can be slidably removed from the 7 and 8, respectively, to move the manifold 100 from the sealing configuration to the bleed configuration. This results in creating a second suction path SSP under the tray 176.

[0050] The tray 176 is configured to be moved within the accessory sleeve 113 in a proximal-distal direction. More specifically, the accessory sleeve 113 is inserted distally into the accessory sleeve 113 and proximally into the accessory sleeve 113. The accessory sleeve 113 is configured to be removed from the accessory sleeve 113. During removal of the tray 176 from the tray 176, the second suction path SSP is used to remove the collected tissue samples. Minimizing collapse aids in removal of tray 176 from accessory sleeve 113. For the most part, the second suction path S passes without encountering the tissue collection cavity 182 of the tray 176. Although the air is directed through the SP, some air may be directed over or through the upper edge 202 of the seal member 154. It can be moved around and into the tissue collection cavity 182 .

[0051] The base portion 184 includes at least one rib 2 disposed within the tissue collection cavity 182. 00. In the most general sense, the rib 200 may be located near the base 184. The tissue collection cavity 182 is separated (divided) into at least two pockets 204. , when the tray 176 is removed from the accessory sleeve 113, at least one of When the pocket 204 is a low pressure area, the tissue collection cavity 182 Any air encountered is forced with sufficient force to dislodge or expel the collected tissue sample. Ribs 200 are used to secure the tray 17 from the accessory sleeve 113. 6 before, during, and after removal of the collected tissue sample along the base portion 184 It is further understood that a barrier can be provided to prevent migration.

[0052] The base portion 184 has at least two ribs disposed therein along with the tissue collection cavity 182. 200. The ribs 200 can extend between the opposing sides 185. With continued reference to FIGS. 9-11, the rib 200 is connected to each of the opposing sides 185. In one example, the ribs are elongated and extend along the longitudinal axis of the tray 176. 11. In other words, the longitudinal axis of the tray 176 is The adaxial axis is oriented in the proximal-distal direction, and the ribs 200 are oriented transverse to the longitudinal axis LA. This configuration prevents the accessory sleeve from sliding in the direction of removal of the tray 176 (and therefore during removal). 113). , thereby providing low pressure regions within the plurality of pockets 204.

[0053] In some embodiments, multiple ribs 200 are provided. For example, in the illustrated embodiment The base includes three ribs 200a-200c that define four pockets 204a-204d. The following disclosure is directed to the three ribs 200a-200c. However, any number of ribs is contemplated. Ribs 200a-200c are equally spaced from each other. The ribs 200a to 200c may be spaced apart and / or oriented parallel to one another. 200c may be generally straight and continuous in configuration, or may have irregular shapes (e.g., zigzag). The positions and orientations of the ribs 200a to 200c may be different from those described above. Pockets 204a to 204d are arranged in series between proximal portion 206 and distal portion 190. In other words, the pockets 204a to 204d are arranged almost adjacent to each other in the proximal and distal directions ( FIG. 11 shows the rib 200a positioned between the proximal portion 206 and the first rib 200a. A first pocket 204a is defined between the first rib 200a and the second rib 200b. A second pocket 204b is defined between the second rib 200b and the third rib 200c. a third pocket 204c defined between the third rib 200c and the distal portion 190; The fourth pocket 204d is shown. The pockets 204a-204d are tissue collection cavities. The proximal-distal alignment may be related to the accessory sleeve. During removal of the tray 176 from the chamber 113, the collected tissue sample is deposited in the pocket 204a. When moving between ~204d, redundancy can be provided. For example, The collected tissue sample placed in the first pocket 204a is then transferred to the second pocket 204. b, it remains within the low pressure region (region II) of the tissue collection cavity 182. Further air in the tissue collection cavity 182 transports the collected tissue sample to a second It is unlikely that the item will be moved further from pocket 204b to a third pocket 204c, etc. The possibility of this being related to sufficient force to dislodge or expel the collected tissue sample is entirely unknown. It's highly unlikely.

[0054] Referring again to FIGS. 9-11, base portion 184 is arcuate between opposing sides 185. The ribs 200a to 200c may be arc-shaped, and the base The base portion 184 may have a contour that is complementary to the arcuate shape of the base portion 184. Opposite the upper arcuate surface 208 that partially defines the tissue collection cavity 182 is a lower arcuate surface (particularly The ribs 200a to 200c may extend upward from the upper arcuate surface 208. Extending from the rib 200a, the rib 200b extends to conform to the contour of the upper arcuate surface 208. In such an embodiment, the rib 200a 200c is the shaft height, and as can be seen generally from FIGS. 9 and 10, The ribs 200a-200c may appear sun-moon shaped (measured perpendicular to the longitudinal axis). (when specified) 0.5 mm, 1 mm, 2 mm, or 3 mm may extend upwardly from upper arcuate surface 208 by a torr or more millimeters. In one embodiment, ribs 200a-200c extend upwardly by approximately 1 millimeter. In another convention, the ribs 200a-200c extend from the depth of the tissue-collecting cavity 182. 0% upwardly from the upper arcuate surface 208. Additionally or alternatively, The ribs 200a to 200c are formed such that at least almost the entirety of the ribs 200a to 200c is at the interface 210 (where opposing side portions 185 transition into base portion 184) It may extend upwardly from the arcuate surface 208 .

[0055] With reference to what will be further described in connection with the sealing edge 212, the rib 200a extends into the airflow AF. The effect of ∼200°C is introduced with reference to Figure 15. In known systems, the tray After the airflow is partially removed, the airflow assaults the tray in a distal direction, creating turbulence within the tray 176. Turbulent airflow often causes tissue samples, such as polyps, to be collected. This causes a pinball-like effect in the tissue samples. The pinball-like effect of the pull TS ejects it from the tray through the exposed portion of the tray. As shown schematically in FIG. 15, airflow AF can be directed through tissue collection cavity 182. When striking distally within the The tissue sample TS encounters (is directed towards) a low pressure region within the pocket 204b. In the illustrated example, the airflow AF extends above the rib 200c adjacent to the tissue sample T. There is a high probability that the ball will come into contact with the upper surface of the S, causing the pinball-like effect mentioned above. Furthermore, the illustrated example is unlikely to have the necessary lift to 200c, which is oriented transversely to the direction of F, shows tissue sample TS adjacent to rib 200c. 00 before, during, and after removal of the tray 176 from the accessory sleeve 113 , the movement of the collected tissue sample along the base portion 184 can be mechanically prevented.

[0056] As previously mentioned, a plurality of hole features 186 are defined within the base portion 184. A feature 186 is located in the aspiration path for collecting tissue samples. before, during, and after removal of the tray 176 from the accessory sleeve 113. 184. The tissue sample collection system 184 is configured to further limit or prevent movement of the collected tissue sample along the base portion 184. 9-11, the plurality of hole features 186 may be formed by the rib 200a. The plurality of hole features 186 may be disposed between the first pocket and the second pocket. The first pocket 204a, the second pocket 204b, the third pocket 204c, and / or the fourth pocket In the illustrated embodiment, the plurality of hole features 186 may be disposed within the slot 204d. , are disposed in each of the four pockets 204a to 204d.

[0057] The hole features 186 may be arranged in groups 214. When used, a group refers to two or more groups equally spaced apart from each other by a first distance. The plurality of groups 214 themselves are defined to include the above (more than two) hole features. , are spaced apart from one another by a second distance greater than the first distance. , dashed lines defining the boundaries of the first group 214a and dashed lines defining the boundaries of the second group 214b. The first and second groups 214a, 214b are shown in the dashed lines defining the base portion 184. are separated from each other by a center aspect 216 of The width of the central surface 216 is the width of the hole features 11 of the first and second groups 214a, 214b. 86. The first and second groups 214a, 214b of the illustrated embodiment b each includes five rows of hole features 186 longitudinally arranged along the base portion 184. Groups 214 may include two, three, four, six, or more rows of hole features. It should be understood that the pocket 204 may also include a pocket 186. There are two groups 214 for each of a to d. Similarly, there are three groups 214 in the pocket 204. It should be understood that there may be one, five, or more groups. The pockets 204 do not have to contain the same number of groups and / or and groupings that, among other things, provide the desired flow characteristics through the tissue collection cavity 182. This may vary based on the

[0058] The base 184 is arcuate and concave between opposing sides 185 to provide a tissue support. The sample TS may descend to the central plane 216 under the action of gravity, as shown in FIG. The absence of the plurality of hole features 186 in the central surface 216 prevents the airflow from passing through the plurality of hole features 186. This airflow reduces the possibility of tissue samples moving upward through the 184 and possibly distally within the tissue collection cavity 182. At least in this respect, the rib 200 a to 200c, and a plurality of groups 214 are trays from the accessory sleeve 113. Movement of tissue sample TS within basket 180 before, during, and after removal of 176 Work together to limit

[0059] As previously described in detail, the flexible portion 160, neck region 172, and gap of the seal member 154 The gap G is the gap between the second suction path SSP and the bleeder 100 when the manifold 100 is in the bleed configuration. The upper region 170 of the seal member 154 is located below the accessory opening 176. When remaining engaged with the mouth 111, the bleed arrangement provides a first suction path FSP However, the tissue collection cavity 182 is not exposed to the environment. The tray 176 is positioned proximal to the accessory opening 111. When actively removed, the airflow AF can enter the tissue collection cavity 182. The advantage of this tray 176 is that it slows the onset of any airflow AF entering the tissue collection cavity 182. The tissue collection cavity 182 includes a sealing edge 212 configured to allow the airflow AF within the tissue collection cavity 182 to flow. The delayed start of the second flow is particularly noticeable in the lower part of the ribs 200a-200c and the basket 180. In combination with the suction path SSP, the collected tissue samples from the tray 176 Prevent removal and discharge.

[0060] The seal member 154 may include a shelf 155 extending distally from a flange portion 156. The flange portion 156 includes a sealing surface 157. The shelf portion 155 is configured to support the accessory sleeve. 113. The accessory opening 111 is disposed in sealing engagement with a plurality of inner surfaces defining the accessory opening 111. One of these inner surfaces is the upper barrier 103. In some embodiments, the previously introduced The proximal portion 206 extends from the shelf 155. The proximal portion 206 defines the tissue collection cavity 182. For example, FIG. 10 shows a cross-section of a slit extending between opposing sides 185. a proximal portion 206 that includes an upstanding surface 220 that extends from the proximal end of the tissue collection cavity 182; The wall 198 may slope downward in a distal direction, away from the upright surface 220.

[0061] The proximal portion 206 includes a sealing edge 212. The sealing edge 212 is in contact with the uppermost edge of the upstanding surface 220. Additionally or alternatively, sealing edge 212 may be considered to be a top surface 222 of shelf 155. In other words, the shelf 155 and the proximal portion 206 may be approximately flush in appearance. Alternatively, the shelves 155 and baskets 180 may be unitary. The sealing edge 212 may be separate (but may be formed as a single unit). When removably positioned within accessory sleeve 113, the accessory is attached to the shelf. Displaced away from flange portion 156 so as to extend a greater distance within resleeve 113 Referring to FIG. 12, the sealing edge 212 is positioned between the shelf 155 and the accessory opening. The upper barrier with the border identified at 223 being significantly more distal than the seal engagement at 111 103. For example, the distance between the flange portion 156 and the sealing edge 212 is The separation should be at least 3 mm, 5 mm, 7 mm, or 9 mm. It can be 1 / 2 a millimeter or more.

[0062] The sealing edge 212 is secured to the tray 176 when it is removed from the accessory sleeve 113. This delays the onset of any airflow AF entering the fabric collection cavity 182. 1 shows the tray 176 in a resting or fully inserted position, and the manifold in a sealed configuration. The inner surface 224 of the distal portion 190 of the tray 176 is inlet bore 114a. The first suction path FSP is therefore located distal to the distal-most portion 226 of the suction tube, the inlet through the bore 114a, the tissue collection cavity 182, the transfer bore 125, and the exit It extends into a manifold volume 108 that leads to an opening 109. Collected tissue sample , the tissue sample TS is deposited in the second pocket 204 adjacent to the second rib 200b. 13 shows the tray 176 in the second position, and FIG. The tray 176 is shown in the third position. To move, the user applies an input to the first and second adjustment members 118a, 118b. For example, the tray 176 is pulled in the proximal direction by grasping the gripping portion. The flexible region 160 allows the tray 176 to move freely into the accessory sleeve upon pinching. Before or simultaneously with the initiation of proximal movement within the manifold 113, It can be instantly moved from a seal configuration to a bleed configuration (see, for example, Figure 8).

[0063] FIG. 13 shows the tray 176 positioned more proximally in the second position than in the first position. The seal surface 157 and the abutment created by moving the manifold 100 to the bleed configuration In addition to the space between the accessory sleeve 111 and the accessory opening 111, a further gap is provided between the accessory sleeve 111 and the accessory opening 111. The airflow is provided by the proximal movement of the tray 176 in the second The first suction path SSP can be passed through the second suction path F. The sealing edge 212 is in sealing engagement with the lower surface 218 of the upper barrier 103. Thus, in the second position, airflow is directed into the tissue collection cavity 182. In the illustrated example, the tissue sample TS is inserted into the second pocket adjacent to the second rib 200b. The tray 176 remains in the slot 204b, and the inner surface 224 of the distal portion 190 of the tray 176 is in the inlet bore 1 It remains positioned distal to the distal-most portion 226 of 14a.

[0064] FIG. 14 shows a further increased clearance between the sealing surface 157 and the accessory opening 111. 1 shows the tray 176 in a third position (more proximal to the first and second positions) in which the tray 176 is positioned. The sealing edge 212 is no longer in sealing engagement with the lower surface 218 of the upper barrier 103. In other words, the sealing edge 212 is moved proximally of the accessory opening 111, At this point, at least a portion of the tissue collection cavity 182 is exposed to the surroundings. The suction path TSP is located between the tissue collection chamber 102 and the sealing edge 212, specifically between the upper barrier 103. The airflow entering the cavity 182 may be provided. The movement of the sample TS is controlled by (i) the ribs 200a to 200c forming a pocket 2 that provides a low pressure region. (ii) the ribs 200a to 200c define the barriers ( and (iii) the base portion 184 is arcuate and the central surface 216 has a plurality of holes. Any one of the advantageous features between the plurality of groups 214 of features 186 can be minimized or eliminated on multiple basis.

[0065] Once the sealing edge 212 is no longer in sealing engagement with the upper barrier 103, the tray 17 The inner surface 224 of the distal portion 190 of the inlet bore 114a is no longer located distal to the distal-most portion 226 of the inlet bore 114a. In other words, the distal portion 190 is positioned such that the tissue-collecting cavity 182 is not exposed to the surroundings. As the tissue moves, it begins to traverse the inlet bore 114a. Among other advantages, this configuration When the sample TS is moving within the tray 176, the tissue sample TS moves to the distal portion 190. Additionally, the distal portion 190 across the inlet bore 114a prevents the first suction This effectively eliminates the path FSP and creates a fourth suction path XSP. The fourth suction path XSP is , suction tube, inlet bore 114a, accessory sleeve 113 distal to tray 176, through the spheric bore 125 and into the manifold volume 108 to the outlet opening 109 The tray 176 extends from the accessory sleeve 113 to the transfer bore 125. Distal slot 23 is provided in leg 131 to accommodate fourth suction path XSP for movement to 0 (see FIG. 10). Thus, the third suction chamber in the tissue collection cavity 182 can Despite the existence of the suction path TSP, the second suction path SSP and the fourth suction path XSP The volume flow rate allowed by this is significantly larger compared to the third suction path TSP, and the fluid dynamics are The third suction path TSP has a relatively small volume flow rate and disturbs the collected tissue sample. In particular, the ribs 200a to 200b determine the path of least resistance. In combination with the group 214 of hole features 186, the user can Confidently remove tray 176 with minimal risk of unintentional loss of fabric samples can be done.

[0066] In some embodiments, the cap portion 106 and the body 104 are detachable from one another. 1 and 2, the cap portion 106 is attached to at least the body 104. At least one keyway 148 or at least one keyway 148 configured to be removably coupled with the body connector. Each includes one key 146 or head coupler. The keys 146 are diametrically opposed to each other. and may have a plurality of keys 146 extending proximally from the cap portion 106. 8 may have a plurality of keyways 148 that are diametrically opposed to one another. The shaft may include a shank and a barb extending from the shank. As a result, during assembly of the manifold 100 and When it is desired to couple the cap portion 106 to the body 104, the cap portion 106 may be The barb 164 is attached to the body 104 so as to be rotationally aligned with the insert in the keyway 148. After the barb extends through the insertion portion, the cap portion 106 is attached to the body 104. 148. The key 146 is rotated relative to the keyway 148 to move the key 146 into an interference fit configuration. The ball prevents axial movement of the cap portion 106 relative to the body 104 and is secured to a body 104 to form a housing 102 of the manifold 100. It can be considered.

[0067] The cap portion 106 and / or the body 104 are capped. The cap portion 106 is in a locking configuration to be fixed to the body 104, or the cap portion 106 is in a locking configuration to be fixed to the body 104. Indicia 15 configured to indicate whether the device is in an unlocked configuration that can be separated from 104 0, 152. More particularly, in the lock configuration, the key 146 may include the As described above, in order to prevent axial movement of the cap portion 106 relative to the body 104, the keyway 1 48. Indicia 150 on cap portion 106 are shown in FIGS. 104. The lock icon and the unlock icon may be included on the main body 104. Indicia 150 indicates that manifold 100 is in a locked configuration or that manifold 100 is in a locked configuration. One of the lock and unlock icons based on whether the The arrow may be configured to point adjacent to the arrowhead. Of course, the reverse configuration is also possible. Figures 1 and 2 show a lock icon with an arrow pointing towards it. 1 shows the manifold 100 in a locking configuration. When the main body 106 rotates relative to the cap 106, the arrow moves relative to the cap 106, unlocking the It is positioned adjacent to and facing the icon.

[0068] The removable connection between the cap portion 106 and the body 104 is formed by the filter element 133. can provide access to the manifold volume 108 disposed therein. Among other advantages, access to the filter element 133 allows for further access during certain surgical procedures. Waste materials, most notably the Polyps or tissue samples may be allowed to be retrieved by the user. International Publication WO2013 / 090579 (of which: The entire contents of which are incorporated herein by reference are used to collect polyp or tissue samples. In some embodiments, the present invention discloses a manifold that includes a tissue trap for The manifold 100, including the cap 106, provides additional support to aid in the collection of tissue samples. The cap portion 106 may be required to be separated from the body 104. When the manifold volume 104 of the body 104 is filled, the steps of the method described above are reversed. 8 may be accessed.

[0069] In some embodiments, the cap portion 106 and the body 104 are bonded together using a suitable bonding process, For example, rigidly connected by spin welding, solvent bonding, adhesives, mechanical fasteners, etc. As previously mentioned, the housing 102 is a single unit so that there are no separate heads and bodies. Alternatively, the housing 102 may be of monolithic construction. Suitable manufacturing processes for this include, among others, injection molding, 3D printing, computer numerical This may include controlled (CNC) machining, polymer casting, vacuum forming, and blow molding. Suitable materials for forming the housing 102 include polymers, composites, metals, ceramics, and combinations thereof. The material may be sufficiently durable to prevent degradation when exposed to waste materials. Maintains integrity under vacuum levels provided by medical waste collection systems and is corrosion resistant Polyethylene, polypropylene, polyvinyl chloride, poly Polyethylene terephthalate (PET, PETE), polystyrene, polycarbonate, and and poly(methyl methacrylate), polymers that are manipulable in low-cost, disposable embodiments. It may be particularly well suited for hold 100.

[0070] Some embodiments can be described with reference to the following exemplary clauses.

[0071] Clause 1 - A first suction path is provided in a sleeve having an opening and is removably disposed therein. a tray configured to collect a tissue sample drawn therethrough, the tray comprising: wherein the tray is disposed in sealing engagement with the opening when removably positioned within the sleeve; a seal member configured to seal the seal member, the seal member including a resilient flexible portion; a first adjustment member extending from the seal member and spaced apart from the first adjustment member; The second adjustment member is positioned in the opposite direction to the first and second adjustment members. a basket extending from the first suction path, the basket receiving the liquid drawn through the first suction path. The first and second adjustment members define a plurality of hole features for collecting tissue samples from the body. , positioned opposite the resilient flexible portion and providing a second suction path through the opening and sleeve. and resiliently and pivotably moving at least a portion of the seal member away from the opening. The tray is configured to receive input to operate the tray.

[0072] Clause 2 - The basket shall have a void space defined between the basket and the sealing member. 1. The method of claim 1, further comprising: Tray as described.

[0073] Clause 3 - The basket shall comprise a base, and a and opposing sides coupled to the base, a plurality of hole features defined within the base, The base is arcuate in shape and concave between the opposing sides. Tray.

[0074] Clause 4 - extending along the base and configured to pass (form) a second suction path The method according to any one of clauses 1 to 3, further comprising: Tray.

[0075] Clause 5 - A train according to clause 4, wherein each of the opposed rails defines a slot. stomach.

[0076] Clause 6 - The resilient flexible portion includes a living hinge including a thinned portion of the sealing member. Clause 1 - A tray according to any one of clauses 5 to 5.

[0077] Clause 7 - A first suction path is provided in a sleeve having an opening and is removably disposed therein. a tray configured to collect a tissue sample drawn therethrough, the tray comprising: wherein the tray is disposed in sealing engagement with the opening when removably positioned within the sleeve; the seal member includes an upper region and a lower region, and a seal member configured to a first adjustment member extending from the lower region and spaced apart from the first adjustment member; a second adjustment member disposed in the upper region of the basket; and a basket extending from the upper region in a direction opposite to that of the first adjustment member. , the basket defining a plurality of hole features for collecting tissue samples, No portion of the seat extends from the area below the seal member, and the first and second adjustment members are A second suction path is provided through the opening and sleeve without disturbing the collected tissue sample. the lower region of the seal member is moved away from the opening relative to the upper region to The tray is configured to accept an input to pivot the lower region.

[0078] Clause 8 - The basket shall have a void space between the basket and the area below the sealing member. a neck region having a reduced cross-sectional profile of the basket as defined, Trays as described in clause 7.

[0079] Clause 9 - The basket shall comprise a base, and a and opposing sides coupled to the base, a plurality of hole features defined within the base, The ray extends along the base and includes a plurality of opposed suction channels configured to pass through the second suction path. 9. A tray according to clause 7 or clause 8, further comprising a rail of

[0080] Clause 10 - A traction device as described in Clause 9, wherein each of the opposed rails defines a slot. Ray.

[0081] Clause 11 - A first suction path is removably disposed within a sleeve having an opening. a tray configured to collect tissue samples drawn through the tray; is disposed in sealing engagement with the opening when the tray is removably disposed within the sleeve. The seal member includes a rib including a thinned portion of the seal member. an upper region and a lower region separated by a hinge; an adjustment member extending from the upper region; a basket extending from the seal member in a direction opposite the member, the basket being adapted to engage the tissue The adjustment member includes a plurality of hole features for collecting samples, and the adjustment member passes through the opening and the sleeve. and moving a lower region of the seal member away from the opening to provide a second suction path. and receiving an input to pivot the lower region relative to the upper region about the living hinge so as to A tray that is configured to

[0082] Clause 12 - The basket shall be such that a void space is defined between the basket and the sealing member. Clause 1 includes a neck region having a reduced cross-sectional profile of the basket so that the basket can be 1. The tray according to claim 1.

[0083] Clause 13 - The basket comprises a base, which collectively define a tissue collection cavity; and opposing sides coupled to the base, wherein the plurality of hole features are defined within the base; The base is arcuate in shape and concave between the opposing sides. Tray as described.

[0084] Clause 14 - An opposing member extending along the base and configured to pass a second suction path therethrough. 14. The tray according to any one of clauses 11 to 13, further comprising a plurality of rails.

[0085] Clause 15 - Each of the opposed rails defines a slot, as described in Clause 14. Tray.

[0086] Article 16 - Trays for collecting tissue samples that are drawn in under suction (vacuum) wherein the tray is configured to be removably placed within a sleeve having an opening. and a tray that seals with the opening when the tray is removably placed within the sleeve. a seal member configured to be disposed in the seal member; an adjustment member extending from the seal member; a basket coupled to the support member, the basket collectively defining the tissue collection cavity. a base, and opposing sides coupled to the base, and configured to collect a tissue sample, as defined in a plurality of hole features defined in a base for collecting the basket; a first cross-sectional profile defined by the opposing side and the boundary between the upper surfaces of the opposing side; the basket having a neck region extending from the seal member in a direction opposite to the adjustment member. The neck region further includes a lower connecting surface of the neck region and an upper surface of the opposing side. a second cross-sectional profile defined by the void space and the tissue collection cavity; The second cross-sectional profile is larger than the first cross-sectional profile as defined between the members. A smaller tray.

[0087] Clause 17 - The base is arcuate in shape and concave between the opposing sides. Clause 1 6. The tray according to claim 6.

[0088] Clause 18 - Clause 16 or further including a plurality of opposed rails extending along the base. Trays as described in clause 17.

[0089] Clause 19 - Each of the opposed rails defines a slot, as described in Clause 18. Tray.

[0090] Clause 20 - A first suction path is removably disposed within a sleeve having an opening. a tray configured to collect tissue samples drawn through the tray; is disposed in sealing engagement with the opening when the tray is removably disposed within the sleeve. The seal member includes a resilient flexible portion and a seal member configured to be inserted into the seal member. and extending away from the opening to provide a second suction path through the opening and sleeve. and receiving an input for resiliently and pivotally moving at least a portion of the seal member. and a basket coupled to the seal member, The scaffold includes a base, a sac, and a base coupled thereto so as to collectively define a tissue collection cavity. opposing sides, a plurality of hole features in the base for collecting tissue samples, and a tissue collection The legs include a plurality of opposed rails extending along the base in a direction away from the collection cavity. The tray further includes a leg configured to pass a second suction path therethrough.

[0091] Clause 21 - Each of the opposed rails defines a slot, as described in Clause 20. Tray.

[0092] Clause 22 - The basket further includes walls that collectively define a tissue collection cavity, The tissue sample is removed from the seal member so that it is visible through the sleeve when viewed from above. 22. A tray according to any one of clauses 1 to 21, configured to be spaced apart. .

[0093] Clause 23 - further comprising a distal end extending from the base and extending between the opposed sides; 23. The traction device of any one of clauses 1 to 22, wherein the distal end includes an additional plurality of hole features. Ray.

[0094] Clause 24 - A manifold for collecting tissue samples through a suction tube, comprising: a sleeve including an upper barrier that is at least partially transparent, and a tray configured to be disposed in sealing engagement with the opening when removably disposed within the sleeve a seal member attached to the seal member, an adjustment member extending from the seal member, and a seal member extending in a direction opposite to the adjustment member. a basket extending from the tube member, the basket being opaque and adapted to receive tissue samples; a base defining a plurality of hole features for collecting the a wall extending downwardly away from the seal member, the wall including a base, opposing sides, and The walls collectively define a tissue collection cavity, and the walls, when viewed from above, extend through the upper barrier. The tissue sample is configured to be spaced away from the seal member as seen in the figure. , manifold.

[0095] Clause 25 - The wall is spaced from the sealing member to allow the tissue sample to descend towards the base. 25. The manifold of claim 24, wherein the manifold is a ramp that slopes downward so that the

[0096] Clause 26 - The sleeve includes shelves defining valleys (recesses) between the shelves, and a second suction channel. A manifold according to clause 24 or clause 25, wherein the passage extends through the valley.

[0097] Clause 27 - A manifold for collecting tissue samples through a suction tube, The tool includes a tray according to any one of clauses 1 to 22 and a sleeve. hold.

[0098] Article 28 - Sample under vacuum from medical waste collection assembly including receiver 1. A method of collecting a liquid comprising: coupling a suction tube to an inlet fitting of a manifold defining an inlet bore; and disposing a manifold within the opening of the receiver, wherein the tray comprises: (ii) a sealing member of the tray is disposed in sealing engagement with the opening; and (iii) a distal portion of the tray is disposed in the inlet port. (iii) the tissue collection cavity of the tray opens toward the inlet bore. a manifold removably disposed within the sleeve at a first position such that the manifold is and operating the medical waste collection assembly with the tray in the first position. wherein the sample is drawn into the tissue collection cavity through a first suction path; and applying an input to resiliently move the first and second adjustment members toward each other. to the first and second adjustment members, and a lower portion of the seal member is provided with a second suction path. and applying an input to the first and second adjustment members, the first and second adjustment members moving away from the opening to provide an input. and moving the first and second adjustment members while moving the tray from the first position to the second position. and maintaining the input force to the seal member such that the seal member moves away from the opening. The tray seal edge remains in sealing engagement with the upper barrier that defines the sleeve. and the distal portion of the tray remains positioned distal to the inlet bore in the second position, input and maintaining the first and second adjustments while moving the tray from the second position to the third position. The force applied to the joint member is maintained, and the seal member is then moved further away from the opening. and the sealing edge of the tray defines a sleeve to provide a third suction path. The upper barrier is disengaged and the distal portion of the tray is opened, eliminating the first suction path and opening the fourth suction path. and moving the input to a third position proximal to the inlet bore to provide a path for the input. Methods including:

[0099] Clause 29 - Providing an input to the first and second adjustment members, and adjusting the tray to the first The steps of moving the first position to the second position are performed simultaneously. Law.

[0100] The foregoing description is not intended to be exhaustive or to limit the present invention to any particular form. The terminology which has been used is intended to be in the nature of words of description rather than of limitation. Many modifications and variations are possible in light of the above teachings, and the present invention may be practiced in accordance with the teachings of the present invention as specifically described. It may be implemented in other ways different from those shown.

Claims

1. The assembly is performed under vacuum by being removably placed in a sleeve having an opening. A tray configured to collect fabric samples, A tray is provided in sealing engagement with the opening when removably positioned within the sleeve. a seal member configured to be disposed when the a basket extending from the seal member; Equipped with The basket includes a base portion and a distal end portion, the base portion and the distal end portion collectively defining a tissue collection cavity. Opposed sides coupled to a base; The base portion, together with the tissue collection cavity, provides a tissue sample collection cavity. defining a plurality of hole features; the base portion includes a plurality of ribs disposed within the tissue collection cavity. 。

2. The assembly is performed under vacuum by being removably placed in a sleeve having an opening. A tray configured to collect fabric samples, A tray is provided in sealing engagement with the opening when removably positioned within the sleeve. a seal member configured to be disposed when the a basket extending from the seal member; Equipped with The basket includes a base portion and a distal end portion, the base portion and the distal end portion collectively defining a tissue collection cavity. Opposed sides coupled to a base; The base portion, together with the tissue collection cavity, provides a tissue sample collection cavity. defining a plurality of hole features; The base portion extends between the opposing sides and defines the tissue collection cavity. A tray with ribs that divide the pockets.

3. The assembly is performed under vacuum by being removably placed in a sleeve having an opening. A tray configured to collect fabric samples, A tray is provided in sealing engagement with the opening when removably positioned within the sleeve. a seal member configured to be disposed when the a basket extending from the seal member; Equipped with The basket has a width such that the basket is elongated and has a longitudinal axis. and The basket includes a base portion and a distal end portion, the base portion and the distal end portion collectively defining a tissue collection cavity. Opposed sides coupled to a base; The base portion, together with the tissue collection cavity, provides a tissue sample collection cavity. defining a plurality of hole features; The base portion includes ribs within the tissue collection cavity, the ribs being elongated and A tray oriented with an axis transverse to the longitudinal axis.

4. The assembly is performed under vacuum by being removably placed in a sleeve having an opening. A tray configured to collect fabric samples, A tray is provided in sealing engagement with the opening when removably positioned within the sleeve. a seal member configured to be disposed when the a basket extending from the seal member; Equipped with The basket includes a base portion and a distal end portion, the base portion and the distal end portion collectively defining a tissue collection cavity. Opposed sides coupled to a base; The base portion, together with the tissue collection cavity, provides a tissue sample collection cavity. defining a plurality of hole features; The base portion is defined between an upper surface and an opposing lower surface, and the base portion is a distance sufficient to create a pocket, which is a low pressure area, when the pressure is removed from within the sleeve. a tray comprising ribs extending upwardly from said top surface by a distance of 100 mm;

5. The assembly is performed under vacuum by being removably placed in a sleeve having an opening. A tray configured to collect fabric samples, A tray is provided in sealing engagement with the opening when removably positioned within the sleeve. a seal member configured to be disposed when the a proximal portion extending from the seal member; opposing side portions coupled to the proximal portion; a base portion coupled to the opposing side, and a distal portion coupled to the base portion and the opposing side. a basket having a proximal portion, an opposing side portion, a base portion, and a front portion; The distal portions collectively define a tissue collection cavity, and the base portion defines a distal end of the distal portion that is in contact with the tissue collection cavity. the basket, together with the tee, defining a plurality of hole features for collecting the tissue samples. To and within the tissue collection cavity and disposed in series between the proximal and distal portions. a rib defining at least two pockets; Equipped with The at least two pockets are configured to be spaced apart when the tray is removed from within the sleeve. Associated with low pressure areas, tray.

6. 6. The tray of claim 5, wherein the at least two pockets comprise four pockets. 。

7. 6. The method of claim 5, wherein one of the pockets is defined between the rib and the proximal portion.

7. The tray according to claim 6.

8. 6. The method of claim 5, wherein one of the pockets is defined between the rib and the distal portion.

7. The tray according to claim 6.

9. The basket has a width such that the basket is elongated and has a longitudinal axis. and the ribs are elongated and oriented along an axis transverse to the longitudinal axis.

6. The tray according to claim 2, claim 4, or claim 5, wherein:

10. The tray of claim 1 , wherein the plurality of hole features are disposed between the ribs.

11. The tray of claim 1 , wherein the ribs further comprise three ribs.

12. The traction control device according to any one of claims 2 to 5, wherein the rib further comprises three ribs. Ray.

13. 13. The tray of claim 12, wherein the three ribs are equally spaced from one another. 。

14. The three ribs define four pockets in the base portion, and the plurality of hole features define the four pockets.

14. A tray according to claim 12 or claim 13, wherein the tray is within each of the four pockets.

15. The three ribs according to any one of claims 12 to 14, wherein the three ribs are parallel to each other. Tray.

16. The base is arcuate in shape and concave between the opposing sides, and the ribs , and is arcuate and contoured complementary to the arcuate shape of the base portion. Item 14. The tray according to any one of items 13.

17. The plurality of hole features are arranged in at least two groups, according to claims 1 to 1.

7. A tray according to any one of claims 6 to 6.

18. Each of the at least two groups is oriented longitudinally along the base portion.

18. The tray of claim 17, comprising at least two rows of holes.

19. 18. The tray of claim 17, wherein the rib separates the at least two groups.

20. The assembly is performed under vacuum by being removably placed in a sleeve having an opening. A tray configured to collect fabric samples, A tray is provided in sealing engagement with the opening when removably positioned within the sleeve. a seal member configured to be disposed when the a basket extending from the seal member; Equipped with The basket includes a base portion and a distal end portion, the base portion and the distal end portion collectively defining a tissue collection cavity. Opposed sides coupled to a base; the base portion includes ribs that divide the tissue collection cavity into a plurality of pockets; The base portion defines a plurality of hole features in each pocket, and each pocket defines a plurality of hole features. a plurality of groups of hole features, the hole features being equally spaced a first distance from one another; the plurality of groups are spaced apart by a second distance greater than the first distance. Trays that are spaced apart from each other by a distance.

21. Each of the plurality of groups includes at least one longitudinally oriented group along the base portion.

21. The tray of claim 20, comprising two rows of holes.

22. The assembly is performed under vacuum by being removably placed in a sleeve having an opening. A tray configured to collect fabric samples, A tray is provided in sealing engagement with the opening when removably positioned within the sleeve. a seal member configured to be disposed when the a ledge extending from the seal member, the seal member being in sealing engagement with the opening; a complementary size to the sleeve so as to be disposed within the sleeve when the sleeve is and the shelf portion is shaped as a proximal portion extending from the shelf; opposing side portions coupled to the proximal portion; a base portion coupled to the opposite side portion, and a distal portion coupled to the base portion and the opposite side portion. A basket with Equipped with The proximal portion, the opposing side portions, the base portion, and the distal portion form a tissue collection cavity. collectively define the The base portion, together with the tissue collection cavity, provides a tissue sample collection cavity. defining a plurality of hole features; A tray wherein the sealing edge of the proximal portion is flush with the upper surface of the shelf portion.

23. a top surface of the proximal portion, including the sealing edge, is flush with a top surface of the shelf.

23. A tray according to 22.

24. The assembly is performed under vacuum by being removably placed in a sleeve having an opening. A tray configured to collect fabric samples, A tray is provided in sealing engagement with the opening when removably positioned within the sleeve. a seal member configured to be disposed when the a ledge extending from the seal member, the seal member being in sealing engagement with the opening; a complementary size to the sleeve so as to be disposed within the sleeve when the sleeve is and the shelf portion is shaped as a proximal portion extending from the shelf; opposing side portions coupled to the proximal portion; a base portion coupled to the opposite side portion, and a distal portion coupled to the base portion and the opposite side portion. A basket with Equipped with The proximal portion, the opposing side portions, the base portion, and the distal portion form a tissue collection cavity. collectively define the The base portion, together with the tissue collection cavity, provides a tissue sample collection cavity. defining a plurality of hole features; When the tray begins to be removed from the sleeve, air ingress into the sleeve Ingress of air is prevented near the proximal portion, while ingress of air into the sleeve is prevented near the base portion. The proximal portion extends from the shelf by at least 5 millimeters to allow for close coverage. , tray.

25. The shelf has a thickness defined between the distal surface and the seal member, the thickness being 5.

25. The tray of claim 24, which is smaller than a millimeter.

26. 26. Claim 24 or claim 25, wherein the upper surface of the proximal portion is flush with the upper surface of the shelf. The tray described in

27. a manifold for collecting tissue samples through a suction tube, a housing having a sleeve defining an opening; Tray and Equipped with the sleeve includes an inlet fitting defining an inlet bore opening into the sleeve; The tray is A seal is formed between the opening and the tray when the tray is removably positioned within the sleeve. a seal member configured to be disposed in engagement; a proximal portion coupled to the seal member; opposing side portions coupled to the proximal portion; a base portion coupled to an opposing side thereof; and a base portion coupled to the opposing side thereof. a basket having a distal portion; Equipped with The proximal portion, the opposing side portions, the base portion, and the distal portion form a tissue collection cavity. collectively define the The base portion, together with the tissue collection cavity, provides a tissue sample collection cavity. defining a plurality of hole features; the proximal portion includes a sealing edge; The distance between the opening and the inlet bore is greater than the distance between the sealing edge and the distal portion. A smaller manifold.

28. a manifold for collecting the tissue sample through a suction tube, A tray according to any one of claims 1 to 26; The sleeve; A manifold comprising:

29. a manifold for collecting tissue samples through a suction tube, a sleeve defining an opening; Tray and Equipped with The tray is The tray is inserted into and removed from the sleeve in a proximal-distal direction. a seal member configured to be disposed in sealing engagement with the opening when the seal member is inserted into the opening; a basket extending from the seal member and collectively defining a tissue collection cavity; The basket includes a base portion and opposing sides coupled to the base portion. To and Equipped with The base portion, together with the tissue collection cavity, provides a tissue sample collection cavity. defining a plurality of hole features; The base portion includes a rib disposed within the tissue collection cavity, the rib having a front A plurality of pockets are defined within the tissue collection cavity and disposed in the proximal and distal directions. 、 The pocket is configured to open when the tray is removed from the sleeve. configured to provide a region of low pressure to retain the tissue sample within one of the Manifold.

30. 30. The manifold of claim 29, wherein the ribs are oriented toward the longitudinal axis of the tray. 。

31. a manifold for collecting tissue samples through a suction tube, a sleeve defining an opening; Tray and Equipped with The tray is The tray is inserted into and removed from the sleeve in a proximal-distal direction. a seal member configured to be disposed in sealing engagement with the opening when the seal member is inserted into the opening; a ledge extending from the seal member, the seal member sealingly engaging the opening; a complementary size to the sleeve so as to be disposed within the sleeve when the sleeve is the shelf being sized and shaped; a proximal portion extending from the shelf; an opposing side portion coupled to the proximal portion; a base portion coupled to the distal end portion, and a distal portion coupled to the base portion and the opposing side portion. With a basket provided, Equipped with The proximal portion, the opposing side portions, the base portion, and the distal portion form a tissue collection cavity. collectively define the The base portion, together with the tissue collection cavity, provides a tissue sample collection cavity. defining a plurality of hole features; The seal member is disengaged from the opening and the shelf is removed from the sleeve. When the proximal portion is removed, the sealing edge of the proximal portion remains temporarily engaged with the upper surface of the sleeve. A manifold configured to accommodate

32. 32. The method of claim 31, wherein the proximal portion extends from the shelf by at least 5 millimeters. manifold.

33. The assembly is performed under vacuum by being removably placed in a sleeve having an opening. A tray configured to collect fabric samples, A tray is provided in sealing engagement with the opening when removably positioned within the sleeve. a seal member configured to be disposed when the a basket coupled to the seal member; Equipped with The basket includes a base portion and a distal end portion, the base portion and the distal end portion collectively defining a tissue collection cavity. Opposed sides coupled to a base; The base portion, together with the tissue collection cavity, provides a tissue sample collection cavity. defining a plurality of hole features; the base portion is arcuate in shape and concave between the opposed sides; The base portion includes ribs within the tissue collection cavity, the ribs extending from the base portion. The tray has an arc shape complementary to the arc shape of the tray.

34. 34. The tray of claim 33, wherein the ribs are crescent-shaped.

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