Embryo visceral organ imaging observation device
By designing an imaging observation device for embryonic internal organs, and using a microscope and an air bladder to drive the positioning plate to unfold mouse embryos, the problems of cumbersome operation and high damage in existing technologies have been solved, and stable unfolding and precise observation of embryonic internal organs have been achieved.
Patent Information
- Application Number
- CN202422374232.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-29
- Publication Date
- 2025-10-28
- Estimated Expiration
- 2034-09-29
AI Technical Summary
Existing embryonic visceral organ imaging and observation devices require squeezing multiple limb parts in sequence when fixing mice, which is cumbersome to operate and causes damage to the embryo.
An imaging observation device for embryonic internal organs was designed, which uses a microscope, support rod, imaging ring, mounting plate, push plate, positioning plate, microscope camera and imaging display. The positioning plate is moved by the downward movement of the microscope lens, so as to achieve stable unfolding and positioning of mouse embryos. Combined with an annular air bladder, piston cylinder, push rod, air inlet tube and air delivery mechanism, the operation process is simplified.
This method enables stable development and precise observation of mouse embryos, improving operational convenience and observation results while reducing damage to the embryos.
Smart Images

Figure CN223473900U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of medical device technology, specifically to an imaging observation device for embryonic internal organs. Background Technology
[0002] Mammalian embryonic development is a complex and dynamic process involving the formation and differentiation of multiple organs and tissues. By imaging and observing the internal organs of mouse embryos, scientists can intuitively understand the key events such as morphological changes, cell migration, and differentiation of these organs during development.
[0003] A search revealed that patent document CN218572481 U discloses a device for harvesting internal organs from embryonic mice. This device can extend the limbs of a curled-up embryonic mouse by fixing it in place. The chest and abdomen of the embryonic mouse are positioned by a trunk positioning groove, which is less prone to displacement and facilitates dissection. The cutting groove allows the operator to operate the scalpel in a straight line, solving the problem of easy displacement during dissection in the prior art. The ice box can continuously provide a cold source for the dissection table, providing the necessary low-temperature environment for dissection, which helps to improve dissection efficiency and specimen quality.
[0004] However, when using the above-mentioned device to fix the mouse, it is necessary to squeeze multiple limbs of the mouse in sequence, which is a cumbersome operation and causes significant damage to the embryo. Utility Model Content
[0005] In view of the problems existing in the above-mentioned embryonic visceral organ imaging observation device, this utility model is proposed.
[0006] Therefore, the purpose of this invention is to provide an imaging observation device for embryonic internal organs, which solves the problem of needing to compress multiple limbs of the mouse sequentially when fixing it.
[0007] To achieve the above objectives, this utility model provides the following technical solution:
[0008] An imaging observation device for embryonic internal organs includes a microscope. The microscope includes a lens part, a base, and a support column. The support column is fixedly disposed on the top of the base. The lens part is slidably sleeved on the outside of the support column, and a locking knob is provided between the side of the lens part and the outer wall of the support column. A microscope camera is fixedly disposed on the top of the lens part. An imaging display is fixedly disposed on the upper end of the outer wall of the support column. The microscope camera is connected to the imaging display.
[0009] The base has multiple support rods fixedly mounted on its top, and an imaging ring is fixedly mounted on the top of the multiple support rods. Two symmetrically arranged mounting plates are fixedly mounted on both sides of the outer wall of the imaging ring. Mounting rods are fixedly mounted inside the mounting plates. Push plates are rotatably fitted onto the walls of the mounting rods, and positioning plates are fixedly mounted on the lower ends of the push plates.
[0010] Preferably, the bottom of the imaging ring is fixed with two symmetrically arranged fixing plates, and the bottom of the two fixing plates is jointly fixed with an annular airbag, which is configured in conjunction with a plurality of push plates.
[0011] Preferably, the mounting rod is fitted with a torsion spring, and the two ends of the torsion spring are fixedly connected to the mounting rod and the push plate, respectively.
[0012] Preferably, a piston cylinder is fixedly provided at the lower end of the outer wall of the support column, a movable piston is slidably provided inside the piston cylinder, a push rod is fixedly provided on the side wall of the movable piston, the end of the push rod passes through the piston cylinder and extends to the outside, an air inlet pipe is provided between the piston cylinder and the annular airbag, and an air delivery mechanism is provided on the rod wall of the push rod.
[0013] Furthermore, the air supply mechanism includes a drive screw, a vertical plate is fixedly provided on the top of the piston cylinder, the drive screw is rotatably disposed inside the vertical plate, and a sliding plate is threadedly sleeved on the rod wall, the sliding plate is fixedly sleeved with the push rod, and a drive mechanism is provided on the rod wall of the drive screw.
[0014] Preferably, the driving mechanism includes a rack and a gear. The rack is fixedly disposed on the lower end of the outer wall of the lens portion, and the gear is fixedly sleeved with the driving screw and cooperates with the rack.
[0015] Preferably, all of the positioning plates are arc-shaped and are silicone soft plates.
[0016] Preferably, the outer wall of the piston cylinder is provided with a clamp, and is fixedly connected to the support column through the clamp.
[0017] Preferably, a transmission cable connects the microscope camera and the imaging display.
[0018] The technical effects and advantages provided by this utility model in the above technical solution are as follows:
[0019] 1. This utility model, through the provision of a microscope, support rod, imaging ring, mounting plate, mounting rod, push plate, positioning plate, microscope camera and imaging display, enables the stable unfolding and positioning of a mouse embryo before observing the internal organs of the embryo through a microscope, ensuring accurate and clear observation of the internal organs of the embryo.
[0020] 2. This utility model, through the provided annular airbag, piston cylinder, movable piston, push rod, air inlet pipe, air delivery mechanism and drive mechanism, can drive multiple positioning plates to move by the downward movement of the microscope's lens section, thereby completing the unfolding of mouse embryos and improving the ease of operation for imaging observation. Attached Figure Description
[0021] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this utility model. For those skilled in the art, other drawings can be obtained based on these drawings.
[0022] Figure 1 It is a structural diagram of the utility model;
[0023] Figure 2 For the utility model Figure 1 Enlarged schematic diagram of part A;
[0024] Figure 3 For the utility model Figure 1 Enlarged schematic diagram of part B;
[0025] Figure 4 This is a three-dimensional structural diagram of the annular airbag of this utility model;
[0026] Figure 5 This is an internal sectional view of the piston cylinder of this utility model.
[0027] Explanation of reference numerals in the attached figures:
[0028] 1. Lens unit; 2. Base; 3. Support column; 4. Locking knob; 5. Microscope camera; 6. Imaging display; 7. Support rod; 8. Imaging ring; 9. Mounting plate; 10. Mounting rod; 11. Push plate; 12. Positioning plate; 13. Fixing plate; 14. Annular airbag; 15. Torsion spring; 16. Piston cylinder; 17. Moving piston; 18. Push rod; 19. Air inlet pipe; 20. Drive screw; 21. Vertical plate; 22. Slide plate; 23. Rack; 24. Gear. Detailed Implementation
[0029] To enable those skilled in the art to better understand the technical solution of this utility model, the present utility model will be further described in detail below with reference to the accompanying drawings.
[0030] This utility model discloses an imaging observation device for embryonic internal organs.
[0031] Example 1
[0032] This utility model provides, for example Figure 1-5An embryonic visceral organ imaging observation device is shown, including a microscope. The microscope includes a lens part 1, a base 2 and a support column 3. The support column 3 is fixedly mounted on the top of the base 2. The lens part 1 is slidably sleeved on the outside of the support column 3, and a locking knob 4 is provided between the side and the outer wall of the support column 3. A microscope camera 5 is fixedly mounted on the top of the lens part 1. An imaging display 6 is fixedly mounted on the upper end of the outer wall of the support column 3. The microscope camera 5 is connected to the imaging display 6, and a transmission cable is provided between the microscope camera 5 and the imaging display 6.
[0033] Multiple support rods 7 are fixedly mounted on the top of the base 2. An imaging ring 8 is fixedly mounted on the top of the multiple support rods 7. Two symmetrically arranged mounting plates 9 are fixedly mounted on both sides of the outer wall of the imaging ring 8. An mounting rod 10 is fixedly mounted inside the mounting plate 9. A push plate 11 is rotatably sleeved on the rod wall of the mounting rod 10. A positioning plate 12 is fixedly mounted on the lower end of the push plate 11. Multiple positioning plates 12 are all arc-shaped and are all silicone soft plates. A torsion spring 15 is sleeved on the rod wall of the mounting rod 10. The two ends of the torsion spring 15 are fixedly connected to the mounting rod 10 and the push plate 11, respectively.
[0034] Before observing the internal organs of a mouse embryo, the mouse embryo is placed on a glass slide, which is then placed above the base 2 of the microscope. At this time, the bottom of the lens 1 of the microscope can observe the mouse embryo through the imaging ring 8. Before observing the mouse embryo, it can be laid flat and unfolded. At this time, multiple positioning plates 12 are set on the surface of the mouse embryo due to their own softness. Then, multiple push plates 11 can be pushed, causing the push plates 11 to rotate under the rotation support of the mounting rod 10. At this time, the multiple positioning plates 12 can move and push the limbs of the mouse embryo, so that the mouse embryo changes from a curled-up state to an unfolded state. At this time, the lens 1 of the microscope can observe the internal organs directly and clearly. With the cooperation of the microscope camera 5 and the imaging display 6, the internal observation of the microscope can be displayed directly from the outside, improving the observation effect.
[0035] Example 2
[0036] Example 2, based on Example 1, aims to enable multiple push plates 11 to rotate simultaneously and drive the positioning plate 12 to unfold the embryo, such as... Figure 1 and Figure 4As shown, two symmetrically arranged fixing plates 13 are fixed at the bottom of the imaging ring 8. An annular airbag 14 is fixed at the bottom of the two fixing plates 13. The annular airbag 14 is configured to cooperate with multiple push plates 11. A piston cylinder 16 is fixed at the lower end of the outer wall of the support column 3. A clamp is provided on the outer wall of the piston cylinder 16 and it is fixedly connected to the support column 3 through the clamp. A movable piston 17 is slidably inserted inside the piston cylinder 16. A push rod 18 is fixed on the side wall of the movable piston 17. The end of the push rod 18 passes through the piston cylinder 16 and extends to the outside. An air inlet pipe 19 is connected between the piston cylinder 16 and the annular airbag 14.
[0037] After the location of the mouse embryo and the positions of the multiple positioning plates 12 are determined, the push rod 18 can be pushed, causing the push rod 18 to drive the moving piston 17 to move inside the piston cylinder 16. By compressing the internal space of the piston cylinder 16 through the moving piston 17, the air inside the piston cylinder 16 can enter the annular airbag 14 through the air inlet pipe 19, causing the annular airbag 15 to malfunction and push the multiple push plates 11, thereby driving the push plates 11 to rotate and drive the positioning plates 12 to unfold the embryo.
[0038] Example 3
[0039] Example 3, based on Example 2, involves positioning the embryo to ensure stable movement of the moving piston 17 inside the piston cylinder 16, such as... Figure 1-3 and Figure 5 As shown, the push rod 18 has an air supply mechanism on its rod wall. The air supply mechanism includes a drive screw 20. A vertical plate 21 is fixedly provided on the top of the piston cylinder 16. The drive screw 20 is rotatably disposed inside the vertical plate 21. A sliding plate 22 is threadedly sleeved on the rod wall. The sliding plate 22 is fixedly sleeved with the push rod 18.
[0040] The drive screw 20 has a drive mechanism on its rod wall. The drive mechanism includes a rack 23 and a gear 24. The rack 23 is fixedly mounted on the lower end of the outer wall of the lens part 1. The gear 24 is fixedly sleeved with the drive screw 20 and is configured to cooperate with the rack 23.
[0041] After the slide containing the mouse embryo is placed on the base 2, the longitudinal position of the lens section 1 can be adjusted with the support of the support column 3, and the position of the lens section 2 can be fixed with the help of the locking knob 4. During the downward adjustment of the lens section 1, the rack 23 moves down and drives the gear 24 to rotate, so that the gear 24 drives the drive screw 20 to rotate. At this time, under the sliding limit inside the piston cylinder 16, the slide plate 22 can drive the push rod 18 to move laterally, thereby completing the airflow delivery, which facilitates the rapid unfolding of multiple positioning plates 12 to complete the unfolding of the embryo, and improves the convenience of observation of the internal organs of the embryo.
[0042] The foregoing description only illustrates certain exemplary embodiments of the present invention. Undoubtedly, those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.
Claims
1. An imaging observation device for embryonic internal organs, comprising a microscope, characterized in that, The microscope includes a lens part (1), a base (2) and a support column (3). The support column (3) is fixedly mounted on the top of the base (2). The lens part (1) is slidably sleeved on the outside of the support column (3), and a locking knob (4) is provided between the side and the outer wall of the support column (3). A microscope camera (5) is fixedly mounted on the top of the lens part (1). An imaging display (6) is fixedly mounted on the upper end of the outer wall of the support column (3). The microscope camera (5) is connected to the imaging display (6). The top of the base (2) is fixedly provided with multiple support rods (7), and the top of the multiple support rods (7) is fixedly provided with an imaging ring (8). Two symmetrically arranged mounting plates (9) are fixedly provided on both sides of the outer wall of the imaging ring (8). An mounting rod (10) is fixedly provided inside the mounting plate (9). A push plate (11) is rotatably sleeved on the rod wall of the mounting rod (10). A positioning plate (12) is fixedly provided at the lower end of the push plate (11).
2. The embryonic visceral organ imaging observation device according to claim 1, characterized in that, The bottom of the imaging ring (8) is fixed with two symmetrically arranged fixing plates (13), and the bottom of the two fixing plates (13) is fixed with an annular airbag (14), which is configured in conjunction with multiple push plates (11).
3. The embryonic visceral organ imaging observation device according to claim 1, characterized in that, The mounting rod (10) has a torsion spring (15) sleeved on its wall, and the two ends of the torsion spring (15) are fixedly connected to the mounting rod (10) and the push plate (11) respectively.
4. The embryonic visceral organ imaging observation device according to claim 1, characterized in that, A piston cylinder (16) is fixedly provided at the lower end of the outer wall of the support column (3). A movable piston (17) is slidably provided inside the piston cylinder (16). A push rod (18) is fixedly provided on the side wall of the movable piston (17). The end of the push rod (18) passes through the piston cylinder (16) and extends to the outside. An air inlet pipe (19) is provided between the piston cylinder (16) and the annular airbag (14). An air delivery mechanism is provided on the rod wall of the push rod (18).
5. The embryonic visceral organ imaging observation device according to claim 4, characterized in that, The air delivery mechanism includes a drive screw (20), a vertical plate (21) is fixedly provided on the top of the piston cylinder (16), the drive screw (20) is rotatably disposed inside the vertical plate (21), and a sliding plate (22) is threadedly sleeved on the rod wall. The sliding plate (22) is fixedly sleeved with the push rod (18), and a drive mechanism is provided on the rod wall of the drive screw (20).
6. The embryonic visceral organ imaging observation device according to claim 5, characterized in that, The driving mechanism includes a rack (23) and a gear (24). The rack (23) is fixedly disposed on the lower end of the outer wall of the lens part (1). The gear (24) is fixedly sleeved with the driving screw (20) and is configured to cooperate with the rack (23).
7. The embryonic visceral organ imaging observation device according to claim 1, characterized in that, All of the aforementioned positioning plates (12) are arranged in an arc shape and are all silicone soft plates.
8. The embryonic visceral organ imaging observation device according to claim 4, characterized in that, The piston cylinder (16) is provided with a clamp on its outer wall and is fixedly connected to the support column (3) through the clamp.
9. The embryonic visceral organ imaging observation device according to claim 1, characterized in that, A transmission cable connects the microscope camera (5) and the imaging display (6).
Citation Information
Patent Citations
Sampling device for visceral tissues and organs of embryonic mouse
CN218572481U