Magnetic separation device

Abstract

The utility model discloses a magnetic separation device and relates to the technical field of magnetic bead adsorption separation equipment. The reactor is used for producing magnetic beads, the magnetic assembly is arranged on the outer side of the reactor in a surrounding mode, the magnetic assembly comprises an upper magnetic group and a lower magnetic group, the magnetic field intensity of the upper magnetic group is larger than that of the lower magnetic group, and the directions of the magnetic fields are opposite. Through the design of the upper magnetic group and the lower magnetic group with different magnetic field intensities, an asymmetric magnetic field is formed, the production conditions of magnetic beads with different specifications can be met, and the compatibility of the device is improved; and the collapse condition of the magnetic beads in a uniform magnetic field is improved, the waste in the magnetic bead production process is reduced, and the separation efficiency of the magnetic beads is improved.

Description

Technical Field

[0001] This utility model relates to the technical field of magnetic microbead adsorption and separation equipment, and more specifically, to a magnetic separation device. Background Technology

[0002] Currently, the production of magnetic beads in mother liquor is mostly conducted in small-batch experimental production, and the corresponding magnetic separation equipment is mainly of a single specification, which cannot be well compatible with the production of products of different specifications and capacities. Generally, permanent magnets are used as the source of the magnetic field, and the relative position of the magnetic field and the reaction tank has certain process parameter requirements. Therefore, in the production of large-scale compatible products, the magnetic field often exerts an additional force on the magnetic beads in the mother liquor, causing the magnetic beads to be drawn away as waste liquid, resulting in waste. Utility Model Content

[0003] To address the shortcomings of existing technologies in producing magnetic beads compatible with large span specifications, this invention provides a magnetic separation device.

[0004] To solve the above-mentioned technical problems, this utility model proposes a magnetic separation device, which includes a reactor for containing magnetic beads and a magnetic assembly surrounding the outside of the reactor. The magnetic assembly includes an upper magnetic group, a lower magnetic group, and a mounting back plate. The magnetic force of the upper magnetic group is greater than that of the lower magnetic group. The reactor is liftable.

[0005] Furthermore, the magnetic field strength of the upper magnetic group is greater than that of the lower magnetic group.

[0006] Furthermore, the upper magnetic assembly includes an upper magnet fixing seat, an upper pressure plate, and a magnet; the upper magnet fixing seat is disposed on the mounting back plate, the upper magnet is installed in the upper magnet fixing seat, and an upper pressure plate is provided on its top.

[0007] Furthermore, the upper magnet is a permanent magnet arranged in an array.

[0008] Furthermore, the mounting backplate and the upper pressure plate are made of carbon steel magnetic material, forming a closed magnetic circuit with the upper magnet.

[0009] Furthermore, the lower magnetic assembly includes a lower magnet fixing seat, a mounting base plate, and a lower magnet; the lower magnet fixing seat is disposed on the mounting back plate, the lower magnet is disposed in the lower magnet fixing seat, and the mounting base plate is provided at its bottom.

[0010] Furthermore, the lower magnet is a permanent magnet arranged in an array.

[0011] Furthermore, the lower magnet fixing base is made of carbon steel.

[0012] Furthermore, the magnetic component is a ring composed of a mirror-symmetrical left half-ring and a right half-ring.

[0013] Furthermore, the magnetic separation device also includes a stainless steel protective cover that covers the upper magnetic assembly and the lower magnetic assembly.

[0014] Compared with the prior art, the present invention has the following advantages:

[0015] This invention, through the design of upper and lower magnetic groups with different magnetic field strengths, can meet the production conditions of magnetic beads of different specifications by adjusting the position of the reactor in the magnetic field, thus improving the compatibility of the device; it can also alleviate the collapse of magnetic beads, reduce waste in the production process, and improve the separation efficiency of magnetic beads. Attached Figure Description

[0016] The features and advantages of this utility model will be more clearly understood by referring to the accompanying drawings. The drawings are schematic and should not be construed as limiting the utility model in any way. In the drawings:

[0017] Figure 1 This is a top view of the magnetic separation device disclosed in this utility model;

[0018] Figure 2 This is a schematic diagram of the magnetic component of the magnetic separation device disclosed in this utility model.

[0019] Figure 3 This is a bottom view of the upper magnetic assembly in the magnetic component of the magnetic separation device disclosed in this utility model.

[0020] Figure 4 This is a top view of the lower magnetic assembly in the magnetic force component of the magnetic separation device disclosed in this utility model.

[0021] Figure 5 This is a schematic diagram of the magnetic separation device disclosed in this utility model for producing large-capacity magnetic beads.

[0022] Figure 6 This is a schematic diagram of the magnetic separation device disclosed in this utility model for producing small-capacity magnetic beads.

[0023] Figure 7 This is a schematic diagram of the magnetic separation device disclosed in this utility model.

[0024] Explanation of reference numerals in the attached figures:

[0025] 1. Magnetic assembly; 11. Mounting back plate; 12. Upper pressure plate; 13. Upper magnetic assembly; 14. Lower mounting base plate; 15. Upper magnet fixing seat; 16. Stainless steel protective cover; 17. Lower magnet fixing seat; 18. Lower magnetic assembly; 2. Reactor. Detailed Implementation

[0026] To make the above-mentioned objectives, features, and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a full understanding of this utility model. However, this utility model can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this utility model. Therefore, this utility model is not limited to the specific embodiments disclosed below.

[0027] A magnetic separation device, such as Figure 1-3 As shown, it includes a reactor 2 for containing magnetic beads and a magnetic assembly 1 surrounding the outside of the reactor 2. The reactor 2 has a suction pipe, the end of which is located at the bottom of the reactor 2. The magnetic assembly 1 includes an upper magnetic group 13, a lower magnetic group 18, and a mounting back plate 11. The magnetic force of the upper magnetic group 13 is greater than that of the lower magnetic group 18. By adjusting the position of the reactor 2 within the asymmetric magnetic field formed by the magnetic assembly 1, the magnetic beads produced in the reactor 2 are subjected to forces in different directions, thereby ensuring the uniformity of the produced magnetic beads. Furthermore, by adjusting the position of the reactor 2, the magnetic beads are distributed along the walls of the reactor 2, reducing the probability of the magnetic beads being sucked away by the suction pipe.

[0028] In some specific implementations, such as Figure 1-2 As shown, the magnetic component 1 is a circular ring composed of a mirror-symmetrical left and right half-ring. This facilitates the installation of the device, the construction of the magnetic field, and the matching of reactors 2 of different sizes.

[0029] In some specific embodiments, the upper magnetic assembly 13 includes an upper magnet fixing seat 15, an upper pressure plate 12, and an upper magnet. The upper magnet fixing seat 15 is disposed on the mounting back plate 11, and the upper magnet is installed in the upper magnet fixing seat 15. The upper pressure plate 12 is provided on its top. There is a repulsive force between the upper magnetic assembly 13 and the lower magnetic assembly 18, whose magnetic fields are opposite in direction. The upper magnet is fixed by the upper pressure plate 12 to maintain the stability of the upper magnetic assembly 13.

[0030] In some specific embodiments, the upper magnet is a permanent magnet arranged in an array, which stabilizes the magnetic field in the upper magnetic assembly 13. The mounting back plate 11 and the upper pressure plate 12 are made of carbon steel with magnetic conductivity, forming a closed magnetic circuit with the upper magnet.

[0031] In some specific embodiments, the lower magnetic assembly 18 includes a lower magnet fixing seat 17, a mounting base plate 14, and a lower magnet; the lower magnet fixing seat 17 is disposed on the mounting back plate 11, and the lower magnet is disposed in the lower magnet fixing seat 17, with the mounting base plate 14 at its bottom. The mounting base plate 14 is made of carbon steel, which can reduce the influence range of the magnetic field on the bottom of the device and reduce the defect rate of the magnetic beads.

[0032] In some specific embodiments, the lower magnet is a permanent magnet arranged in an array, and the lower magnet fixing base 17 is made of carbon steel.

[0033] Furthermore, the magnetic field strength of the upper magnetic assembly 13 is greater than that of the lower magnetic assembly 18. It should be noted that in this invention, the implementation of "the magnetic field strength of the upper magnetic assembly 13 being greater than that of the lower magnetic assembly 18" is not specifically limited; conventional techniques in the art can be used. For example, in some embodiments, when the number of magnets in the upper magnetic assembly 13 and the lower magnetic assembly 18 is the same, the volume of the upper magnet is larger than that of the lower magnet; or, when the magnet particle size is the same, the number of upper magnets is greater than the number of lower magnets. In other specific embodiments, the upper magnetic assembly 13 and the lower magnetic assembly 18 typically need to be sealed separately, and the outer sealing materials of the upper magnetic assembly 13 and the lower magnetic assembly 18 can be selected to achieve different upper and lower magnetic fields. In some specific embodiments, an asymmetric magnetic field can also be achieved by changing the shape of the upper pressure plate 12 and the mounting base plate 14. For example, the mounting base 14 is made of one-piece carbon steel, and the upper pressure plate 12 consists of multiple short carbon steel plates. Even if the magnets of the upper magnetic assembly 13 and the lower magnetic assembly 18 are exactly the same, different fixing methods can be used to fix the upper and lower magnets. After being sealed with an outer casing of the same material, different magnetic field strengths can be presented, thus forming an asymmetrical magnetic field. These specific implementation methods can also be combined arbitrarily.

[0034] In some specific embodiments, the magnetic separation device further includes a stainless steel protective cover 16, which integrally covers and seals the upper magnetic assembly 13 and the lower magnetic assembly 18, thereby enabling the magnetic separation device to be used in underwater and other environments, protecting the stability of the internal magnetic field and the durability of the device.

[0035] In some specific implementations, such as Figure 7 As shown, reactor 2 is connected to a telescopic mechanism that allows it to move up and down; magnetic component 1 is connected to a push-pull mechanism that allows it to move left and right. During production, as the liquid level in reactor 2 decreases, reactor 2 moves upward, causing the liquid level to be flush with or slightly higher than the upper surface of magnetic component 1.

[0036] Working principle:

[0037] When the liquid level is high, such as Figure 5As shown, reactor 2 is located within the magnetic field generated by the upper magnetic group 13 and the lower magnetic group 18. The magnetic beads in the liquid are subject to the buoyancy of the water, the attraction of the surrounding magnetic groups, their own weight, and the supporting force after adhering to the tank wall. After the magnetic beads are separated, the waste liquid is pumped away from the top of the reaction tank. As the liquid is pumped away, the buoyancy acting on the magnetic beads disappears. At this time, the attraction force generated by the upper magnetic group 13 and the lower magnetic group 18 on the magnetic beads is higher than the weight of the magnetic beads themselves. Therefore, the magnetic beads will not move down with the tank wall, and no magnetic beads will be pumped away with the liquid at the bottom of the tank.

[0038] When the liquid level is low, such as Figure 6 As shown, when reactor 2 rises into the magnetic field generated by the upper magnetic group, the adsorption force of the upper magnetic group 13 on the magnetic beads is higher than that of the lower magnetic group 18 on the magnetic beads, which can effectively prevent the magnetic beads from collapsing and improve product quality. After the magnetic beads are separated, as the liquid is pumped away, the adsorption force of the upper magnetic group 13 on the magnetic beads is higher than that of the lower magnetic group 18 on the magnetic beads and the weight of the magnetic beads themselves. Therefore, the magnetic beads will not move down with the barrel wall, and no magnetic beads will be pumped away with the liquid at the bottom of the barrel, thus avoiding waste of magnetic beads.

[0039] Although embodiments of the present invention have been described in conjunction with the accompanying drawings, those skilled in the art can make various modifications and variations without departing from the spirit and scope of the present invention, and such modifications and variations all fall within the scope defined by the appended claims.

Claims

1. A magnetic separation device, comprising a reactor (2) for containing magnetic beads and a magnetic assembly (1) surrounding the outside of said reactor (2), characterized in that, The magnetic assembly (1) includes an upper magnetic group (13), a lower magnetic group (18) and a mounting back plate (11), wherein the magnetic force of the upper magnetic group (13) is greater than that of the lower magnetic group (18); the reactor (2) is liftable.

2. The magnetic separation device according to claim 1, characterized in that, The magnetic field strength is greater than that of the lower magnetic group (18).

3. The magnetic separation device according to claim 1, characterized in that, The upper magnetic assembly (13) includes an upper magnet fixing seat (15), an upper pressure plate (12), and an upper magnet; the upper magnet fixing seat (15) is disposed on the mounting back plate (11), the upper magnet is installed in the upper magnet fixing seat (15), and the upper pressure plate (12) is provided on its top.

4. The magnetic separation device according to claim 3, characterized in that, The upper magnet is a permanent magnet arranged in an array.

5. The magnetic separation device according to claim 3, characterized in that, The mounting backplate (11) and the upper pressure plate (12) are made of carbon steel magnetic material, forming a closed magnetic circuit with the upper magnet.

6. The magnetic separation device according to claim 1, characterized in that, The lower magnetic assembly (18) includes a lower magnet fixing seat (17), a mounting base plate (14), and a lower magnet; the lower magnet fixing seat (17) is disposed on the mounting back plate (11), the lower magnet is disposed in the lower magnet fixing seat (17), and the mounting base plate (14) is provided at its bottom.

7. The magnetic separation device according to claim 6, characterized in that, The lower magnet is a permanent magnet arranged in an array.

8. The magnetic separation device according to claim 6, characterized in that, The lower magnet fixing base (17) is made of carbon steel.

9. The magnetic separation device according to claim 1, characterized in that, The magnetic component (1) is a circular ring composed of a mirror-symmetrical left half ring and a right half ring.

10. The magnetic separation device according to any one of claims 1-9, characterized in that, The magnetic separation device further includes a stainless steel protective cover (16) covering the upper magnetic group (13) and the lower magnetic group (18).

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