Clinical diagnosis kit based on flow fluorescence method

Abstract

The utility model discloses a clinical diagnosis kit based on a flow type fluorescence method, which comprises a sealing cover and a plurality of kit bodies, the plurality of kit bodies are sequentially stacked from top to bottom, and the top end of the uppermost kit body is detachably connected with the sealing cover. A grating plate is connected to the center of the interior of each kit body. And four groups of storage cavities are separately arranged in the space of the kit body at the left end and the right end of the grating plate through a transverse plate and a vertical plate which are arranged in a crossed manner. Two groups of reagent hole sites are formed in each group of storage cavities. And each group of reagent hole sites is movably connected with a separation blade. On one hand, the reagent bottles are prevented from falling off from the reagent hole sites in the transportation process, and on the other hand, medical staff can conveniently grab components of the reagent bottles, and the inspection efficiency is improved.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically a clinical diagnostic reagent kit based on flow cytometry. Background Technology

[0002] In vitro diagnostics (IVD) refers to products and services that obtain clinical diagnostic information by testing human samples (blood, body fluids, tissues, etc.) outside the human body, thereby determining diseases or bodily functions. IVD products mainly consist of diagnostic equipment (instruments) and diagnostic reagents. The IVD industry and laboratory medicine form an organic whole that is both distinct and closely related. The IVD industry is the "tool" and "weapon" of laboratory medicine, while laboratory medicine is the "user" and "market" of the IVD industry; their common goal is to implement IVD. Approximately 80% of clinical diagnostic information comes from IVD, yet its cost accounts for less than 20% of medical expenses. IVD has become an increasingly important component of human disease prevention, diagnosis, and treatment, and is also an increasingly important part of ensuring human health and building a harmonious society.

[0003] Flow cytometry is a multi-index combined diagnostic technique that integrates flow cytometry principles, laser analysis, and high-speed digital signal processing. Using fluorescently encoded microspheres as its core, it achieves high-throughput, high-sensitivity parallel detection. This technology can accurately detect 2-500 different biomolecules simultaneously in a single tube and is widely used in immunoassays, nucleic acid research, enzymatic analysis, ligand recognition analysis of receptors, and many other fields. With the rapid development of the in vitro diagnostics (IVD) industry, the types and quantities of IVD testing reagents are constantly increasing, leading to a growing demand for reagent kit packaging. IVD testing kits, as an important component of IVD testing reagents, play a crucial role in protecting, fixing, and isolating reagents, ensuring that they are not contaminated or damaged during transportation and storage.

[0004] However, some existing diagnostic kits have liner that is either too tight or too loose. A liner that is too tight will cause excessive resistance when the operator picks up the reagent bottle, making it inconvenient to pick it up; while a liner that is too loose will not be able to secure the reagent bottle, causing the reagent to shake and bounce during transportation, which may lead to reagent spillage and damage.

[0005] Therefore, we propose a reagent kit that is both easy to use and can secure the reagent bottle to solve the problems mentioned above, so as to meet the actual needs of testing personnel and further improve the quality of diagnosis and treatment for patients. Utility Model Content

[0006] To address the aforementioned shortcomings in the existing technology, the purpose of this utility model is to provide a clinical diagnostic reagent kit based on flow cytometry, which solves the problem that some existing diagnostic reagent kits have liner that is too tight or too loose. A liner that is too tight will cause excessive resistance when the operator picks up the reagent bottle, making it inconvenient to pick up; while a liner that is too loose cannot fix the reagent bottle, causing the reagent to shake and bounce during transportation, which may lead to reagent spillage and damage.

[0007] The technical solution adopted by this utility model to achieve the above-mentioned objectives is as follows: a clinical diagnostic reagent kit based on flow cytometry, comprising a sealing cap and several reagent kit bodies, wherein the reagent kit bodies are stacked sequentially from top to bottom, and the top of the uppermost reagent kit body is detachably connected to the sealing cap. A grid plate is connected to the center of each reagent kit body. Four sets of storage cavities are respectively arranged in the space of the reagent kit bodies at the left and right ends of the grid plate by a horizontal plate and a vertical plate arranged in a cross pattern. Each set of storage cavities has two sets of reagent well positions. A baffle is movably connected to each set of reagent well positions.

[0008] To further improve the ease of use of clinical diagnostic kits based on flow cytometry, the present invention employs a spring element between the baffle and the reagent well.

[0009] To further improve the ease of use of clinical diagnostic kits based on flow cytometry, the present invention adopts the following solution: the spring component is configured as a tension spring structure, the first end of the tension spring structure is fixedly disposed at the inner bottom of the kit body, and the second end of the tension spring structure is fixedly connected to the baffle.

[0010] To further improve the ease of use of clinical diagnostic kits based on flow cytometry, the present invention adopts the following solution: a buffer sheet is attached to the inner bottom of the baffle.

[0011] To further improve the ease of use of clinical diagnostic kits based on flow cytometry, the present invention adopts the following solution: the buffer sheet is a sponge layer.

[0012] To further improve the ease of use of clinical diagnostic kits based on flow cytometry, the present invention adopts the following solution: the baffle is a square, circular, or arbitrary polygonal structure.

[0013] To further improve the ease of use of clinical diagnostic kits based on flow cytometry, the present invention adopts the following solution: each kit body has a hollow heat-insulating interlayer on its side wall, and the heat-insulating interlayer is filled with a heat-insulating medium.

[0014] To further improve the ease of use of clinical diagnostic kits based on flow cytometry, the present invention adopts the following solution: the heat preservation medium is iron powder, aqueous activated carbon, vermiculite, or water-absorbing resin filler.

[0015] To further improve the ease of use of clinical diagnostic kits based on flow cytometry, the present invention adopts the following solution: several reagent bottles are stored inside the reagent well positions.

[0016] The beneficial effects of this invention are as follows: Each baffle of this clinical diagnostic reagent kit based on flow cytometry can cover the reagent bottle in the reagent well to prevent it from falling off, and also plays a role in preventing it from falling off during transportation; when the baffle is rotated at a certain angle, the covering restriction on the reagent can be released, and when the baffle is pressed down, the corresponding reagent bottle can be exposed for grasping and use. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0018] Figure 2 This is an exploded view of the entire utility model;

[0019] Figure 3 This is a top view of the main body of the reagent kit of this utility model;

[0020] Figure 4 This is a schematic diagram of the internal structure of the reagent well position in the first embodiment of this utility model;

[0021] Figure 5 This is a schematic diagram of the internal structure of the reagent well position in the second embodiment of this utility model.

[0022] In the diagram: 1. Reagent kit body, 2. Sealing cap, 3. Grating plate, 4. Horizontal plate, 5. Vertical plate, 6. Storage cavity, 7. Reagent well, 8. Spring, 9. Baffle, 10. Buffer plate, 11. Reagent bottle. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] Please see Figures 1 to 5This invention discloses a clinical diagnostic reagent kit based on flow cytometry, comprising a sealing cap 2 and several reagent kit bodies 1, which are stacked sequentially from top to bottom. The top of the uppermost reagent kit body 1 is detachably connected to the sealing cap 2. A grid plate 3 is connected to the center of each reagent kit body 1. Four storage cavities 6 are respectively arranged within the space of the reagent kit body 1 at the left and right ends of the grid plate 3, divided by a horizontal plate 4 and a column 5. Each storage cavity 6 has two sets of reagent ports 7. A baffle 9 is movably connected to each reagent port 7, and several reagent bottles 11 are stored inside each reagent port 7. When the operator uses the kit, rotating the corresponding baffle 9 allows for quick removal of the corresponding reagent bottle.

[0025] Furthermore, a spring 8 is provided between the baffle 9 and the reagent hole 7, so that the baffle 9 can be released from covering the reagent bottle 11 when it is rotated 45° by the spring 8.

[0026] Specifically, the spring member 8 is configured as a tension spring structure, with the first end of the tension spring structure fixedly disposed at the inner bottom of the reagent kit body 1, and the second end of the tension spring structure fixedly connected to the baffle 9 so as to rotate to open or close the baffle 9.

[0027] Furthermore, the baffle 9 is square, circular or any polygonal structure, and the shape of the baffle 9 with the highest adaptability can be selected according to actual needs. A buffer sheet 10 is attached to the inner bottom of the baffle 9, and the buffer sheet 10 plays a buffering role when in contact with the reagent bottle.

[0028] Specifically, the buffer sheet 10 is a sponge layer with high elasticity, strong fibers and good elasticity, which can bring the advantages of enhanced support and elastic cushioning.

[0029] In addition, each of the reagent kit bodies 1 has a hollow insulating layer on its sidewall, which is filled with an insulating medium, such as iron powder, hydrated activated carbon, vermiculite, or a water-absorbing resin filler. This insulating structure effectively prevents moisture intrusion, protects against drug deterioration, and significantly extends the effective shelf life of the drugs.

[0030] All standard parts used in this utility model can be purchased from the market, and irregular parts can be customized according to the description and drawings. The specific connection methods of each part adopt conventional methods such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts and equipment adopt conventional models in the prior art. In addition, the circuit connection adopts conventional connection methods in the prior art, which will not be described in detail here. The contents not described in detail in this specification belong to the prior art known to those skilled in the art.

[0031] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A clinical diagnostic kit based on flow cytometry, comprising a sealing cap (2) and several kit bodies (1), characterized in that: Several of the reagent kit bodies (1) are stacked sequentially from top to bottom; The top of the reagent kit body (1) located at the top is detachably connected to the sealing cap (2); Each of the reagent kit bodies (1) has a grid plate (3) connected to the center inside; Four storage cavities (6) are respectively set in the space of the reagent kit body (1) at the left and right ends of the grid plate (3) by a horizontal plate (4) and a vertical plate (5) that are arranged in a cross pattern; Each of the storage cavities (6) is provided with two sets of reagent ports (7); Each reagent well position (7) in each group is movably connected to a baffle (9).

2. The clinical diagnostic kit based on flow cytometry according to claim 1, characterized in that: A spring (8) is provided between the baffle (9) and the reagent hole (7).

3. A clinical diagnostic kit based on flow cytometry according to claim 2, characterized in that: The spring member (8) is configured as a tension spring structure. The first end of the tension spring structure is fixed to the inner bottom of the reagent kit body (1), and the second end of the tension spring structure is fixedly connected to the baffle (9).

4. A clinical diagnostic kit based on flow cytometry according to claim 1, characterized in that: A buffer sheet (10) is attached to the inner bottom of the baffle (9).

5. A clinical diagnostic kit based on flow cytometry according to claim 4, characterized in that: The buffer sheet (10) is a sponge layer.

6. A clinical diagnostic kit based on flow cytometry according to claim 1, characterized in that: The baffle (9) is a square, circular or arbitrary polygonal structure.

7. A clinical diagnostic kit based on flow cytometry according to claim 1, characterized in that: Each of the reagent kit bodies (1) has a hollow heat-insulating interlayer on its side wall, and the heat-insulating interlayer is filled with a heat-insulating medium.

8. A clinical diagnostic kit based on flow cytometry according to claim 7, characterized in that: The insulation medium is iron powder, water-containing activated carbon, vermiculite, or water-absorbing resin filler.

9. A clinical diagnostic kit based on flow cytometry according to claim 1, characterized in that: The reagent well (7) contains several reagent bottles (11).

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