Tumor electric field treatment device

Abstract

The utility model provides a tumor electric field treatment device which comprises an electric field generator for generating alternating current signals and at least one pair of electrode plates electrically connected with the electric field generator, and each electrode plate comprises a flexible circuit board and a plurality of electrode units distributed on the flexible circuit board at intervals. The plurality of electrode units are divided into a plurality of row groups and a plurality of column groups in circuit connection, and a plurality of grounding traces in one-to-one correspondence with the plurality of row groups and a plurality of dual-purpose signal lines in one-to-one correspondence with the plurality of column groups are embedded in the flexible circuit board. Each path of grounding ground wire enables the corresponding part of each electrode unit in the corresponding row group to be short-circuited and grounded; each path of dual-purpose signal line enables the corresponding part of each electrode unit in the corresponding column group to be short-circuited and transmits an alternating current signal to each electrode unit in the corresponding column group in a first mode; and in the second mode, a direct current signal or a temperature detection signal detected by each electrode unit in the corresponding column group is transmitted to each electrode unit in the corresponding column group.

Description

Technical Field

[0001] This application relates to tumor treating fields (TTF) technology, and more particularly to a tumor treating fields device. Background Technology

[0002] Tumor electric field therapy is a treatment that uses low-intensity, medium-to-high-frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, inhibit the separation of intracellular organelles during cell division, and induce apoptosis in mitotic cells, thereby achieving the therapeutic effect on tumors.

[0003] Compared to traditional cancer treatments, TTF has an innovative mechanism of action. Certain physiological characteristics of tumor cells, such as their geometry and high-frequency mitosis, make them susceptible to TTF. TTF disrupts the normal aggregation of microtubules by applying directional forces to intracellular polar particles (such as macromolecules and organelles). These processes can lead to physical damage to the cell membrane and apoptosis. During the telophase of mitosis, the morphology of the cleavage groove leads to an uneven distribution of the electric field around it. Under the influence of TTF, the electric field strength at the cleavage groove is significantly enhanced, causing charged substances in the cell to move towards the cleavage groove, interfering with or even destroying cell structure formation, ultimately leading to cell division failure and apoptosis.

[0004] In existing tumor electric field therapy devices, an electric field application device transmits an alternating current signal for tumor electric field therapy to electrode pads, which then apply an alternating electric field to the patient's tumor site for tumor electric field therapy. When the tumor treatment electric field is applied to the patient's body, heat accumulates at the application site, causing a corresponding increase in temperature. Therefore, it is necessary to monitor the temperature at the application site. If the temperature becomes too high, the electric field intensity needs to be adjusted promptly to reduce the risk of burns to the patient's skin.

[0005] Tumor electric field therapy devices include at least one pair of electrode pads, each containing multiple electrode units. Even when the same alternating current signal is applied to each electrode unit, the heat generated on each unit will vary depending on its location. This means the temperature of each electrode unit across the entire electrode pad will not be completely uniform. Consequently, some electrode units may exceed a preset temperature while others remain at a normal temperature. To improve the effectiveness of tumor electric field therapy, individual control of overheating electrode units is necessary. However, with existing electrode pads, individual control of electrode units requires a conductive trace for each unit within the electrode pad's substrate. This increases the number of conductive traces within the substrate, making the electrode pad less flexible, and also thickens the cables connecting to the electrode pad, increasing its overall weight and hindering proper application.

[0006] Therefore, it is necessary to provide a tumor electric field therapy device that uses fewer conductive traces to control multiple electrode units in a zoned manner. Utility Model Content

[0007] One object of this application is to provide a tumor electric field therapy device to alleviate, reduce or eliminate problems in related technologies.

[0008] This application provides a tumor electric field therapy device, including an electric field generator that generates an alternating current signal and at least a pair of electrode sheets electrically connected to the electric field generator. The electrode sheets include a flexible circuit board and a plurality of electrode units spaced apart on the flexible circuit board. The plurality of electrode units are divided into a plurality of row groups and a plurality of column groups in terms of circuit connection. The flexible circuit board is embedded with a plurality of ground traces corresponding to a plurality of row groups and a plurality of dual-purpose signal lines corresponding to a plurality of column groups. Each ground trace short-circuits a corresponding part of each electrode unit in the corresponding row group to ground. Each dual-purpose signal line short-circuits a corresponding part of each electrode unit in the corresponding column group and transmits an alternating current signal to each electrode unit in the corresponding column group in a first mode, transmits a direct current signal to each electrode unit in the corresponding column group in a second mode, or transmits a temperature detection signal detected by each electrode unit in the corresponding column group.

[0009] According to one embodiment of this application, each electrode unit includes a transducer element for transmitting an AC signal and a temperature sensor for detecting temperature and transmitting a temperature detection signal. The temperature sensor has a ground terminal shorted to the corresponding ground trace and a signal terminal shorted to the corresponding dual-purpose signal line. The transducer element is shorted to the corresponding dual-purpose signal line.

[0010] According to one embodiment of this application, the grounding terminals of the temperature sensors of each electrode unit located in the same row group are all shorted to the same grounding trace.

[0011] According to one embodiment of this application, the transducer elements of each electrode unit located in the same column are all shorted to the same dual-purpose signal line.

[0012] According to one embodiment of this application, the signal terminals of the temperature sensors of each electrode unit located in the same column are all shorted to the same dual-purpose signal line.

[0013] According to one embodiment of this application, all of the multiple grounding traces are disconnected when the dual-purpose signal line transmits an AC signal.

[0014] According to one embodiment of this application, when the multiple grounding traces transmit DC signals or temperature detection signals on the dual-purpose signal lines, only one of them is turned on and the rest are turned off.

[0015] According to one embodiment of this application, the electric field generator has a preset temperature threshold, and the dual-purpose signal line transmits an AC signal with increased voltage or current amplitude to the corresponding electrode unit when the temperature detection signal detected by the temperature sensor is much lower than the preset temperature threshold.

[0016] According to one embodiment of this application, when the temperature detection signal detected by the temperature sensor is close to but still below the preset temperature threshold, the dual-purpose signal line transmits an AC signal with reduced voltage or current amplitude to the corresponding electrode unit.

[0017] According to one embodiment of this application, the dual-purpose signal line stops transmitting AC signals to the electrode unit when the temperature detection signal detected by the temperature sensor exceeds the preset temperature threshold.

[0018] The above description is only an overview of the technical solution of this application. In order to better understand the technical means of this application and to implement it in accordance with the contents of the specification, and to make the above and other objects, features and advantages of this application more obvious and understandable, the following are specific embodiments of this application. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of a tumor electric field therapy device according to an embodiment of this application;

[0020] Figure 2 for Figure 1 A schematic diagram of the electrode pads in the tumor electric field therapy device shown;

[0021] Figure 3 for Figure 1 The diagram shows the circuit connection between one electrode plate and the adapter in the tumor electric field system.

[0022] Figure 4 and Figure 3 Similarly, it is Figure 3 The diagram shows the connection between one electrode plate and another circuit of the adapter.

[0023] Figure 5 for Figure 1 The diagram shows the circuit connection between an electrode plate, an adapter, and an electric field generator in the tumor electric field system.

[0024] Figure 6 for Figure 1 A schematic block diagram of the internal structure of the adapter of the tumor electric field therapy device shown;

[0025] Figure 7 for Figure 1 A schematic block diagram of the internal structure of the electric field generator in the tumor electric field therapy device shown.

[0026] Explanation of reference numerals in the attached figures:

[0027] Tumor electric field therapy device 100, electrode pads 13, first cable 15, adapter 20, second cable 25, electric field generator 30, flexible circuit board 31, electrode unit 33, temperature sensor 34, grounding terminal 34-1, signal terminal 34-2, transducer element 35, diode 36, second power module 32, second controller 37, second communication unit 38, AC signal generator 39, AC signal switch 40, first controller 51, analog-to-digital converter 52, voltage divider resistor 53, grounding switch 54, first grounding switch 54-1, second grounding switch 54-2, third grounding switch 54-3, fourth grounding switch 54-4, bidirectional switching switch 55, first bidirectional switching switch 55-1, second bidirectional switching switch 55-4, etc. Switch 55-2, third bidirectional switch 55-3, fourth bidirectional switch 55-4, fifth bidirectional switch 55-5, first communication unit 56, AC signal line 57, first power module 58, grounding trace 18, first grounding trace 18-1, second grounding trace 18-2, third grounding trace 18-3, fourth grounding trace 18-4, dual-purpose conductive trace 19, first dual-purpose conductive trace 19-1, second dual-purpose conductive trace 19-2, third dual-purpose conductive trace 19-3, fourth dual-purpose conductive trace 19-4, fifth dual-purpose conductive trace 19-5, first connector 60, first plug 61, first socket 62, second connector 70, second plug 71, second socket 72. Detailed Implementation

[0028] The embodiments of the technical solution of this application will now be described in detail with reference to the accompanying drawings. These embodiments are only used to more clearly illustrate the technical solution of this application and are therefore merely examples, and should not be used to limit the scope of protection of this application.

[0029] Figure 1 The diagram shown is a schematic representation of the tumor electric field therapy device 100 of this invention. Figure 1 As shown, the tumor electric field therapy device 100 includes: at least one pair of electrode pads 13, an adapter 20 connected to the electrode pads 13, and an electric field generator 30 connected to the adapter 20. The electric field generator 30 supplies power to the electrode pads 13, causing the electrode pads 13 to generate a therapeutic electric field. The adapter 20 is electrically connected between the electrode pads 13 and the electric field generator 30, for transmitting the alternating current signal generated by the electric field generator 30 to the electrode pads 13. That is, the electric field generator 30 is capable of generating an alternating current signal, which is transmitted to each electrode pad 13 through the adapter 20, thereby generating a therapeutic electric field for treating tumors between the same pair of electrode pads 13. Figure 1As shown, in this embodiment, there are four electrode pads 13. Each electrode pad 13 includes a plurality of identical electrode units 33, and each electrode unit 33 is electrically connected to the adapter 20. Each electrode pad 13 has 20 electrode units 33. In other embodiments, the tumor electric field therapy device 100 may have more or fewer electrode pads 13. In other embodiments, each pair of electrode pads 13 has the same number of electrode units 33, and different pairs of electrode pads 13 may have different numbers of electrode units 33.

[0030] Figure 3 and Figure 4 This diagram illustrates the circuit connections between the electrode pad 13 and the adapter 20 in two operating states of the tumor electric field therapy device 100. It is worth noting that: Figure 3 and Figure 4 The arrangement of electrode units 33 shown is to more clearly illustrate the electrical connection between an electrode piece 13 and the adapter 20. Figure 3 and Figure 4 The arrangement of electrode units 33 shown does not represent their spatial arrangement. (Combined with...) Figure 1 , Figure 3 as well as Figure 4 The electrode sheet 13 includes: a flexible circuit board 31, multiple electrode units 33 electrically connected to the flexible circuit board 31 at intervals, and a first cable 15 electrically connected to the flexible circuit board 31. The flexible circuit board 31 has embedded multiple conductive traces (18, 19), including multiple grounding traces 18 and multiple dual-purpose conductive traces 19. The first cable 15 has multi-core wires (not shown), each of which is electrically connected to one-to-one with the multiple grounding traces 18 and the multiple dual-purpose conductive traces 19 of the flexible circuit board 31. The total number of grounding traces 18 and dual-purpose conductive traces 19 embedded in the flexible circuit board 31 does not exceed 10. Therefore, the number of wires in the first cable 15 does not exceed 10.

[0031] In this embodiment, each electrode sheet 13 has 20 electrode units 33. These 20 electrode units 33 are grouped in the circuit connection according to the order 1 to 20, forming four row groups and five column groups, i.e., the 20 electrode units 33 are arranged in a four-row, five-column configuration. Each electrode unit 33 includes a transducer element 35 and a temperature sensor 34. The temperature sensor 34 includes a ground terminal 34-1 and a signal terminal 34-2. Both the transducer element 35 and the temperature sensor 34 are soldered onto the flexible circuit board 31, and the transducer element 35 is short-circuited to the signal terminal 34-2 of the corresponding temperature sensor 34. Since multiple temperature sensors 34 are correspondingly arranged with multiple electrode units 33, the multiple temperature sensors 34 are also arranged in a four-row, five-column configuration in the circuit connection. It should be noted that this arrangement is for clearer illustration of the electrical connection between the electrode sheet 13 and the adapter 20, and does not represent the spatial arrangement of the electrode units 33. The spatial structure may be as follows: Figure 2 The structure shown is generally array-like, but it can also be other structures, such as petal-shaped or scattering-shaped, and can be regular or irregular. The transducer element 35 is configured to apply an alternating electric field to the patient's tumor site. The temperature sensor 34 is configured to detect the temperature of the patient's body surface in contact with the electrode pad 13 and output a temperature detection signal to the adapter 20. In this embodiment, the multi-purpose conductive trace 19 of the flexible circuit board 31 is respectively arranged in a one-to-one correspondence with multiple columns of the electrode unit 33, and is configured to transmit the AC signal generated by the electric field generator 30 to the transducer element 35 in each electrode unit 33 in the corresponding column. That is, the transducer elements 35 located in the same column are all short-circuited through the same multi-purpose conductive trace 19 of the flexible circuit board 31, and the transducer elements 35 located in different columns are respectively connected in parallel through different multi-purpose conductive traces 19 of the flexible circuit board 31. The dual-purpose conductive trace 19 of the flexible circuit board 31 is electrically connected to the first cable 15, and then electrically connected to the electric field generator 30 via the adapter 20. Furthermore, the dual-purpose conductive trace 19 of the flexible circuit board 31 receives the AC signal generated by the electric field generator 30 through the first cable 15 and the adapter 20.

[0032] Each of the multiple grounding traces 18 is configured to correspond one-to-one with a row group of electrode units 33. Each of the multiple grounding traces 18 is used to sequentially short-circuit and ground the temperature sensor 34 of each electrode unit 12 in each row group. That is, the grounding terminals 34-1 of multiple temperature sensors 34 located in the same row group are all short-circuited through the same grounding trace 18 on the flexible circuit board 31, while the grounding terminals 34-1 of temperature sensors 34 located in different row groups are connected in parallel through different grounding traces 18 on the flexible circuit board 31. During the temperature detection period, only one of the multiple grounding traces 18 is conducting at any given time, while the other three are disconnected.

[0033] Each of the multiplexed dual-purpose conductive traces 19 is further configured to short-connect the signal terminal 34-2 of the temperature sensor 34 of at most one electrode unit 33 in each row group to an external device for receiving detection signals. The signal terminals 34-2 of the temperature sensor 34 connected to each of the multiplexed dual-purpose conductive traces 19 are different to avoid subsequent output of duplicate signals by the dual-purpose conductive traces 19. That is, when the number of electrode units 33 in a row group is the same as the number of dual-purpose conductive traces 19, each dual-purpose conductive trace 19 is electrically connected to the signal terminal 34-2 of the temperature sensor 34 of a different electrode unit 33 in that row group; when the number of electrode units 33 in a row group is less than the number of dual-purpose conductive traces 19, at least one dual-purpose conductive trace 19 is not electrically connected to the signal terminal 34-2 of the temperature sensor 34 of the electrode unit 33, and the remaining dual-purpose conductive traces 19 are electrically connected to the signal terminal 34-2 of the temperature sensor 34 of a different electrode unit 33 in that row group. In this embodiment, the external device used to receive the detection signal is an adapter 20. The signal terminals 34-2 of multiple temperature sensors 34 located in different columns are connected in parallel through different dual-purpose conductive traces 19 of the flexible circuit board 31. The signal terminals 34-2 of multiple temperature sensors 34 located in the same column are all shorted to the same dual-purpose conductive trace 19 of the flexible circuit board 31.

[0034] In this embodiment, with a temperature sensor 34 configured in each electrode unit 33 for temperature detection, the above-described circuit design reduces the number of wires in the first cable 15, preventing the cable from becoming thicker and harder, thus increasing the difficulty of cable fixation; simultaneously, it avoids the increased number of wires in the first cable 15 affecting the adhesion between the electrode pad 13 and the corresponding body surface of the patient's tumor site. The flexible circuit board 31 has a total of 9 embedded grounding traces 18 and dual-purpose conductive traces 19. Specifically, in this embodiment, the flexible circuit board 31 has 4 embedded grounding traces 18 and 5 embedded dual-purpose conductive traces 19. The number of grounding traces 18 is related to the number of rows M of the electrode unit 33, and is greater than or equal to the number of rows M, where M is a positive integer. The number of dual-purpose conductive traces 19 is related to the number of columns N of the electrode unit 33, and is greater than or equal to the number of columns N, where N is a positive integer. The number of lines H embedded in the flexible circuit board 31 of the electrode sheet 13 is equal to the sum of the number of grounding traces 18 and the number of dual-purpose conductive traces 19. In this embodiment, the number of grounding traces 18 is equal to the number of rows M of the electrode unit 33; the number of dual-purpose conductive traces 19 is equal to the number of columns N of the electrode unit 33.

[0035] Multiple electrode units 33 are arranged in a roughly two-dimensional array on the flexible circuit board 31 at intervals. For example... Figure 2As shown, the electrode sheet 13 in this embodiment includes 20 electrode units 33 and 20 temperature sensors 34 corresponding to the electrode units 33. The 20 electrode units 33 are arranged in a four-row and six-column array. Both the first row and the fourth row have four electrode units 33, and both the second row and the third row have six electrode units 33. The four electrode units 33 in each of the first row and the fourth row are located in the columns from the second column to the fifth column, and the six electrode units 33 in each of the second row and the third row are located in the columns from the first column to the sixth column. The 4 electrode units 33 in the first row are divided into region 1, the electrode units 33 in the first column of the second row, the first column of the third row, the second column and the third column of the fourth row are divided into region 2, the electrode units 33 in the sixth column of the second row, the sixth column of the third row, the fourth column and the fifth column of the fourth row are divided into region 3, the electrode units 33 in the second column and the third column of the second row and the second column and the third column of the third row are divided into region 4, and the electrode units 33 in the fourth column and the fifth column of the second row and the fourth column and the fifth column of the third row are divided into region 5. Each region (1 - 5) corresponds to a column group respectively. In some other embodiments, the 20 electrode units 33 can also be arranged in other ways. Of course, in some other embodiments, the electrode sheet 13 can also have other numbers of electrode units 33. In short, the implementation of the present utility model is not limited by the number and arrangement form of the electrode units 33 of the electrode sheet 13.

[0036] Each electrode unit 33 includes a transducer element 35 and a temperature sensor 34. In Figure 3 and Figure 4 In the shown embodiment, the transducer element 35 can be a dielectric ceramic sheet or a polymer dielectric layer made of a polymer material. The temperature sensor 34 can be a thermistor element. Of course, in some other embodiments, the temperature sensor 34 can also be other temperature sensors other than thermistors, and it can be arranged at any position on the electrode unit 33. In this embodiment, each transducer element 35 has a through hole (not labeled) penetrating through the middle, and a corresponding temperature sensor 34 is accommodated in the through hole (not labeled) of each transducer element 35. Each electrode unit 33 can also include a diode 36. The diode 36 is connected in series with the temperature sensor 34 of the same electrode unit 33, and it can prevent the reverse inflow of current to prevent the detection signal from other electrode units 33 from affecting this temperature sensor 34.

[0037] Refer Figure 3 or Figure 4As shown, the electrode sheet 13 of this embodiment includes four ground traces 18, and each ground trace 18 is used to ground the ground terminals 34-1 of the temperature sensors 34 in the same row group. The four ground traces 18 of the electrode sheet 13 are respectively the first ground trace 18-1, the second ground trace 18-2, the third ground trace 18-3, and the fourth ground trace 18-4. Among the four row groups of the electrode sheet 13, the first row group is electrode units 33-1 to electrode units 33-5, the second row group is electrode units 33-6 to electrode units 33-10, the third row group is electrode units 33-11 to electrode units 33-15, and the fourth row group is electrode units 33-16 to electrode units 33-20. Specifically, the first ground trace 18-1 is used to ground electrode units 33-1 to electrode units 33-5 in the first row group; the second ground trace 18-2 is used to ground electrode units 33-6 to electrode units 33-10 in the second row group; the third ground trace 18-3 is used to ground electrode units 33-11 to electrode units 33-15 in the third row group; the fourth ground trace 18-4 is used to ground electrode units 33-16 to electrode units 33-20 in the fourth row group. It should be noted that these ground traces 18 can be selectively closed or opened, which can be achieved by connecting each ground trace 18 in series with a switch respectively, and this will be described in detail below. The above "grounding the electrode unit 33" can refer to grounding the ground terminal 34-1 of the temperature sensor 34 in the electrode unit 33, or it can also refer to connecting the diode 36 in series with the temperature sensor 34 of the same electrode unit 33 and grounding them together. In short, each ground trace 18 shorts and grounds the ground terminals 34-1 of the temperature sensors 34 of all the electrode units 33 in each row group.

[0038] Refer Figure 3 Or Figure 4As shown, the electrode sheet 13 in this embodiment also includes five dual-purpose conductive traces 19. One end of each dual-purpose conductive trace 19 is connected to all electrode units 33 in each row group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting AC signals. That is, for each row group, each dual-purpose conductive trace 19 can be selectively connected to one of the electrode units 33 or not connected to any of the electrode units 33 in that row group to avoid the dual-purpose conductive trace 19 outputting repetitive signals in the future. Specifically, the five dual-purpose conductive traces 19 of the electrode sheet 13 include a first dual-purpose conductive trace 19-1, a second dual-purpose conductive trace 19-2, a third dual-purpose conductive trace 19-3, a fourth dual-purpose conductive trace 19-4, and a fifth dual-purpose conductive trace 19-5. One end of the first dual-purpose conductive trace 19-1 is simultaneously connected to the transducer element 35 and the signal terminal 34-2 of each of the four electrode units 33 (33-1, 33-6, 33-11, and 33-16) and their respective temperature sensors 34 in the first column group; one end of the second dual-purpose conductive trace 19-2 is simultaneously connected to the transducer element 35 and the signal terminal 34-2 of each of the four electrode units 33 (33-2, 33-7, 33-12, and 33-17) and their respective temperature sensors 34 in the second column group; one end of the third dual-purpose conductive trace 19-3 is simultaneously connected to the electrode units 33-3, 33-8, and 33-16 in the third column group. 3-13, Electrode units 33-18: Each of the four electrode units 33 has a transducer element 35 and a signal terminal 34-2 of its respective temperature sensor 34. One end of the fourth dual-purpose conductive trace 19-4 is simultaneously connected to the transducer element 35 and the signal terminal 34-2 of each of the four electrode units 33-4, 33-9, 33-14, and 33-19 located in the fourth column group. One end of the fifth dual-purpose conductive trace 19-5 is simultaneously connected to the transducer element 35 and the signal terminal 34-2 of each of the four electrode units 33-5, 33-10, 33-15, and 33-20 located in the fifth column group. In short, each dual-purpose conductive trace 19 short-circuits the transducer element 35 and the signal terminal 34-2 of each temperature sensor 34 of each electrode unit 33 located in the same column group in parallel for connection to an external device. It should be noted that these dual-purpose conductive traces 19 can selectively transmit AC signals or temperature detection signals. This can be achieved by connecting each dual-purpose conductive trace 19 in series with a bidirectional switching switch 55 and coordinating with the closing or opening of the grounding trace 18, which will be described in detail below.

[0039] Both the multi-path grounding trace 18 and the multi-path dual-purpose conductive trace 19 are conductive traces embedded in the flexible circuit board 31. The flexible circuit board 31 is electrically connected to the first cable 15. The multi-path grounding trace 18 and the multi-path dual-purpose conductive trace 19 embedded in the flexible circuit board 31 are electrically connected to the corresponding wires (not shown) in the first cable 15.

[0040] The tumor electric field therapy device 100 of this embodiment includes at least one pair of electrode pads 13 as described above, an adapter 20 electrically connected to the electrode pads 13, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode pads 13 and the electric field generator 30. The electric field generator 30 provides an alternating current signal to the transducer elements 35 in the plurality of electrode units 33 of the electrode pads 13 via the adapter 20 and the dual-purpose conductive traces 19 of the electrode pads 13, or is used to transmit temperature detection signals output by the temperature sensors 34 in the plurality of electrode units 33. The adapter 20 transmits the alternating current signal generated by the electric field generator 30 to the dual-purpose conductive traces 19 of the electrode pads 13, and is also configured to receive the temperature detection signals output by the multiple dual-purpose conductive traces 19 of the electrode pads 13.

[0041] refer to Figure 3 and Figure 4As shown, the adapter 20 includes: a first controller 51, multiple sets of analog-to-digital converters 52 connected to the first controller 51, multiple sets of voltage-reducing resistors 53 and multiple sets of grounding switches 54 corresponding to each set of analog-to-digital converters 52, multiple sets of bidirectional switching switches 55 corresponding to each set of analog-to-digital converters 52, a first communication unit 56, AC signal lines 57 corresponding to each set of bidirectional switching switches 55, and a first power module 58 connected to the first communication unit 56, the first controller 51, and the multiple sets of analog-to-digital converters 52. The first power module 58 provides DC power VCC to each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unlabeled). These multiple circuit lines (unlabeled) are electrically connected to multiple grounding traces 18 and multiple dual-purpose conductive traces 19 in the flexible circuit board 31 of the corresponding electrode plates 13 via first cables 15. The multiple circuit lines (unlabeled) include multiple AC signal lines 57 that transmit AC signals to the corresponding electrode 13 and are electrically connected to the multiple dual-purpose conductive traces 19 in the flexible circuit board 31 of the corresponding electrode 13; multiple circuit lines (unlabeled) that are electrically connected one-to-one to the multiple dual-purpose conductive traces 19 in the flexible circuit board 31 of the corresponding electrode 13 and are used to power the temperature sensors 34 of the electrode 13 or transmit the temperature detection signal of the electrode 13; and multiple circuit lines (unlabeled) that are electrically connected one-to-one to the multiple ground traces 18 in the flexible circuit board 31 of the corresponding electrode 13. The number l of circuit lines connected by the adapter 20 to one electrode 13 is equal to the sum of the number of rows and columns of the electrode units 33 of the electrode 13 plus one; the number L of circuit lines connected by the adapter 20 to X electrode 13 is equal to X times the number of circuit lines connected to a single electrode 13, that is, L = Xh = X*(M+N+1). The number of groups of grounding switches 54 and the number of groups of bidirectional switching switches 55 are both related to the number of electrode plates 13. The number of groups of grounding switches 54 is the same as the number of groups of bidirectional switching switches 55; and not less than the number of electrode plates 13. Preferably, the number of groups of grounding switches 54 and bidirectional switching switches 55 is the same as the number of electrode plates 13. The following detailed description only takes the electrical connection of an electrode plate 13 with 20 electrode units 33 to the adapter 20 as an example.

[0042] Each group of grounding switches 54 is equipped with multiple grounding switches 54, which are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multiple grounding traces 18 of a corresponding electrode piece 13, and are configured to control the conduction or disconnection of the multiple grounding traces 18. The circuit lines (unlabeled) that are each electrically connected to the multiple grounding traces 18 of the electrode piece 13 are grounded at the end closest to the grounding switch 54. The number of grounding switches 54 in each group of grounding switches 54 is related to the number of grounding traces 18 of the flexible circuit board 31 of the corresponding electrode piece 13, and in this embodiment, the two are equal. Figure 3 or Figure 4 As shown, in this embodiment, the multiple grounding switches 54 are respectively a first grounding switch 54-1, a second grounding switch 54-2, a third grounding switch 54-3, and a fourth grounding switch 54-4. The multiple grounding switches 54 in the same group each control the closing or opening of the corresponding grounding trace 18 of the same electrode plate 13. The first grounding switch 54-1 is used to control the closing or opening of the first grounding trace 18-1 of the corresponding electrode plate 13, and can then cooperate with the corresponding group of bidirectional switching switches 55 to control the energization and de-energization of the temperature sensors 34 of each of the five electrode units 33 from electrode unit 33-1 to electrode unit 33-5 in the first row group of the electrode plate 13; the second grounding switch 54-2 is used to control the closing or opening of the second grounding trace 18-2 of the electrode plate 13, and can then cooperate with the corresponding group of bidirectional switching switches 55 to control the energization and de-energization of the temperature sensors 34 of each of the five electrode units 33 from electrode unit 33-6 to electrode unit 33-10 in the second row group of the electrode plate 13; the... The three-way grounding switch 54-3 is used to control the opening or closing of the third grounding trace 18-3 of the electrode plate 13, and can cooperate with the corresponding set of bidirectional switching switches 55 to control the energization and de-energization of the temperature sensors 34 of each of the five electrode units 33 (33-11 to 33-15) in the third row of the electrode plate 13; the fourth grounding switch 54-4 is used to control the opening or closing of the fourth grounding trace 18-4 of the electrode plate 13, and can cooperate with the corresponding set of bidirectional switching switches 55 to control the energization and de-energization of the temperature sensors 34 of each of the five electrode units 33 (33-16 to 33-20) in the fourth row of the electrode plate 13. The grounding switches 54 can be mechanical switches, such as relays. The grounding switches 54 can also be electronic switches, and each grounding switch 54 can be opened and closed by an additional first controller 51.

[0043] In this embodiment, all sets of grounding switches 54 are electronic switches. The first controller 51 is communicatively connected to the multiple sets of grounding switches 54, and is used to sequentially and cyclically control the opening and closing states of multiple grounding switches 54 in each set, thereby sequentially and individually activating each of the multiple grounding traces 18 of the corresponding electrode pad 13 and coordinating with the switching of the corresponding bidirectional switching switch 55, to continuously and in real-time collect the patient's body surface temperature detected by all temperature sensors 34 on the electrode pad 13. The number of grounding switches 54 in each set is not less than the number of grounding traces 18 on the flexible circuit board 31 of the corresponding electrode pad 13. In this embodiment, the number of grounding switches 54 in each set is the same as the number of grounding traces 18 on the corresponding electrode pad 13.

[0044] Each group of bidirectional switching switches 55 is provided with multiple bidirectional switching switches 55. The multiple bidirectional switching switches 55 in each group are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) corresponding to the multi-purpose conductive traces 19 of the corresponding electrode plate 13. The number of bidirectional switching switches 55 in each group of bidirectional switching switches 55 is related to the number of dual-purpose conductive traces 19 of the flexible circuit board 31 of the corresponding electrode plate 13, which is greater than or equal to the number of dual-purpose conductive traces 19 of the flexible circuit board 31 of the corresponding electrode plate 13. In this embodiment, the two are equal. Each bidirectional switch 55 has two ends labeled 1 and 2. The ends of multiple bidirectional switches 55 in the same group are electrically connected to the corresponding detection channels A, B, C, D, and E of the corresponding set of analog-to-digital converters 52. The ends of each bidirectional switch 55 in the same group are electrically connected to the same corresponding AC signal line 57 and are configured to control the multi-purpose conductive trace 19 to connect to the corresponding AC signal line 57 to transmit AC signals or to connect to the corresponding detection channel of the corresponding set of analog-to-digital converters 52 to receive the temperature detection signal output by the temperature sensor 34.

[0045] like Figure 3 or Figure 4As shown, taking the electrical connection of one electrode plate 13 with the adapter 20 as an example, in this embodiment with 20 electrode units 33, the multiple bidirectional switching switches 55 are respectively the first bidirectional switching switch 55-1, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3, the fourth bidirectional switching switch 55-4, and the fifth bidirectional switching switch 55-5. The multiple bidirectional switching switches 55 in the same group each control the switching of a corresponding dual-purpose conductive trace 19 in the multi-channel dual-purpose conductive trace 19 of the same electrode plate 13 between transmitting AC power signals and transmitting temperature detection signals. Specifically, the first bidirectional switching switch 55-1 is used to control the switching of the first dual-purpose conductive trace 19-1 of the corresponding electrode 13 between transmitting AC signals and transmitting temperature detection signals. This controls the switching between the conduction of each transducer element 35 of the electrode units 33-1, 33-6, 33-11, and 33-16 in the first column of the electrode 13 and the conduction of the signal terminal 34-2 of each temperature sensor 34 of the electrode units 33-1, 33-6, 33-11, and 33-16 in the first column, and coordinates with the corresponding grounding switches 54-1, 54-2, 54-3, and 54-4 to enable the first column of electrode units 33-1, 33-6, 33-11, and 33-16 to transmit AC signals to the patient or output the temperature detection signals collected by the temperature sensors 34 of these electrode units 33 to the corresponding analog-to-digital converter 52. The second bidirectional switching switch 55-2 is used to control the switching of the second dual-purpose conductive trace 19-2 of the corresponding electrode 13 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the conduction of each transducer element 35 of the electrode units 33-2, 33-7, 33-12, and 33-17 in the second column of the electrode 13 and the conduction of the signal terminals 34-2 of each temperature sensor 34 of the electrode units 33-2, 33-7, 33-12, and 33-17 in the second column of the electrode 13. The switching between the two is also coordinated with the corresponding grounding switches 54-1, 54-2, 54-3, and 54-4, so that the second column of electrode units 33-2, 33-7, 33-12, and 33-17 transmits AC signals to the patient or outputs temperature detection signals collected by the temperature sensors 34 of these electrode units 33 to the corresponding analog-to-digital converter 52.The third bidirectional switching switch 55-3 is used to control the switching of the third dual-purpose conductive trace 19-3 of the corresponding electrode pad 13 between transmitting AC signals and transmitting temperature detection signals. This controls the conduction of each transducer element 35 of the electrode units 33-3, 33-8, 33-13, and 33-18 in the third column of the electrode pad 13, and the conduction of the signal terminals 34-2 of each temperature sensor 34 of the electrode units 33-3, 33-8, 33-13, and 33-18 in the third column. It also coordinates with the corresponding grounding switches 54-1, 54-2, 54-3, and 54-4 to enable the third column of electrode units 33-3, 33-8, 33-13, and 33-18 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 34 of these electrode units 33 to the corresponding analog-to-digital converter 52. The fourth bidirectional switching switch 55-4 is used to control the switching of the fourth dual-purpose conductive trace 19-4 of the corresponding electrode 13 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the conduction of each transducer element 35 of the electrode units 33-4, 33-9, 33-14, and 33-19 in the fourth column of the electrode 13 and the conduction of the signal terminals 34-2 of each temperature sensor 34 of the electrode units 33-4, 33-9, 33-14, and 33-19 in the fourth column of the electrode 13. The switching between the two is also coordinated with the corresponding grounding switches 54-1, 54-2, 54-3, and 54-4, so that the fourth column of electrode units 33-4, 33-9, 33-14, and 33-19 can transmit AC signals to the patient or output the temperature detection signals collected by the temperature sensors 34 of these electrode units 33 to the corresponding analog-to-digital converter 52.The fifth bidirectional switching switch 55-5 is used to control the switching of the fifth dual-purpose conductive trace 19-5 of the corresponding electrode 13 between transmitting AC signals and transmitting temperature detection signals. This controls the switching between the conduction of each transducer element 35 of the electrode units 33-5, 33-10, 33-15, and 33-20 in the fifth column of the electrode 13 and the conduction of the signal terminals 34-2 of each temperature sensor 34 of the electrode units 33-5, 33-10, 33-15, and 33-20 in the fifth column. It also cooperates with the corresponding grounding switches 54-1, 54-2, 54-3, and 54-4 to enable the fifth column of electrode units 33-5, 33-10, 33-15, and 33-20 to transmit AC signals to the patient or output the temperature detection signals collected by the temperature sensors 34 of these electrode units 33 to the corresponding analog-to-digital converter 52. When both ends of each bidirectional switching switch 55 are on and one end is off, AC signals can be transmitted to the transducer elements 35 of each electrode unit 33 of the corresponding electrode plate 13. When one end of each bidirectional switching switch 55 is on and both ends are off, it can cooperate with each grounding switch 54 in the corresponding group of grounding switches 54 to transmit the temperature detection signals collected by the temperature sensors 34 of each electrode unit 33 on the electrode plate 13 in a time-division manner. The bidirectional switching switch 55 can be a mechanical switch, such as a relay. The bidirectional switching switch 55 can also be an electronic switch, and each bidirectional switching switch 55 can be switched by an additional first controller 51.

[0046] In this embodiment, all of the multiple sets of bidirectional switching switches 55 are electronic switches. The first controller 51 is communicatively connected to the multiple sets of bidirectional switching switches 55 and is used to control the switching of multiple bidirectional switching switches 55 in each set between their respective terminals 1 and 2, and to cooperate with the closing or opening of the corresponding grounding switch 54, so as to continuously monitor the temperature of the patient's body surface detected by all the temperature sensors 34 on the electrode pad 13 or to transmit AC signals to the patient.

[0047] In this embodiment, each group of analog-to-digital converters 52 is electrically connected to one end of each of the multiple bidirectional switching switches 55 in the corresponding group through multiple circuit lines (unlabeled) within the adapter 20, and is configured to receive temperature detection signals transmitted by the multi-channel dual-purpose conductive traces 19 of the corresponding electrode sheet 13, and convert the temperature detection signals from analog signals to digital signals. Each group of analog-to-digital converters 52 includes multiple detection channels A, B, C, D, and E, and each detection channel A, B, C, D, and E is used to connect to one corresponding dual-purpose conductive trace 19 in the multi-channel dual-purpose conductive traces 19 through the corresponding bidirectional switching switch 55. For example... Figure 3 or Figure 4As shown, each group of analog-to-digital converters 52 includes five detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose conductive trace 19-1 through terminal 1 of the first bidirectional switch 55-1; the second detection channel B is connected to the second dual-purpose conductive trace 19-2 through terminal 1 of the second bidirectional switch 55-2; the third detection channel C is connected to the third dual-purpose conductive trace 19-3 through terminal 1 of the third bidirectional switch 55-3; the fourth detection channel D is connected to the fourth dual-purpose conductive trace 19-4 through terminal 1 of the fourth bidirectional switch 55-4; and the fifth detection channel E is connected to the fifth dual-purpose conductive trace 19-5 through terminal 1 of the fifth bidirectional switch 55-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal collected by the temperature sensor 34 of the electrode unit 33 connected to the corresponding dual-purpose conductive trace 19. In addition, each detection channel A, B, C, D, and E is connected to a first power supply module 58 via a corresponding voltage divider resistor 53 in the adapter 20. The first power supply module 58 provides DC power to the detection channel A, B, C, D, and E.

[0048] In this embodiment, the first communication unit 56 is configured to acquire digital signals output by multiple sets of analog-to-digital converters 52 and send the digital signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage of the AC signal provided to the multiple electrode units 33 of the electrode sheet 13 according to the received digital signals. For example, when any of the received digital signals exceeds a preset threshold, it indicates that the temperature detected by at least one transducer element 35 in the electrode sheet 13 exceeds the preset threshold temperature (e.g., 41°C, 42°C, etc.). At this time, the voltage of the AC signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode units 33 of the electrode sheet 13 becoming too hot when the AC signal is applied, which could cause low-temperature burns to the patient's skin. The preset threshold temperature and the preset threshold can be determined according to human safety thresholds. The first communication unit 56 is controlled by the first controller 51 and serially transmits the digital signals converted by the multiple sets of analog-to-digital converters 52. In this embodiment, the preset temperature threshold can be a value within the range of 36°C to 45°C.

[0049] refer to Figure 5 and Figure 6In this embodiment, the first power module 58 is electrically connected to the second power module 32 of the electric field generator 30 and is configured to supply power to the first controller 51, multiple analog-to-digital converters 52, and the first communication unit 56 of the adapter 20. Each electrode 13 is connected to the adapter 20 via a first connector 60, which is adapted to connect the corresponding electrode 13 to the adapter 20. The first connector 60 includes a first plug 61 located at the end of the first cable 15 away from the electrode 13 and a first socket 62 located on the adapter 20. The first plug 61 and the first socket 62 are press-type spring connectors, meaning the first connector 60 connects the adapter 20 to the electrode 13 using a connector method. Each first cable 15 has five wires electrically connected to each bidirectional switch 55 in a corresponding group of bidirectional switches 55 and four wires electrically connected to each grounding switch 54 in a corresponding group of grounding switches 54. That is, each first connector 60 is electrically connected to a set of bidirectional switching switches 55 and a set of grounding switches 54 corresponding to the adapter 20 through 9 wires; and is connected to the electric field generator 30 through a corresponding AC signal line 57 of the adapter 20.

[0050] A second connector 70 is provided between the adapter 20 and the electric field generator 30, and the second connector 70 is adapted to connect the electric field generator 300 to the adapter 20. The adapter 20 also includes a second cable 25 connected to the second connector 70. The second connector 70 includes a second plug 71 located at the end of the second cable 25 away from the first controller 51 and a second socket 72 located on the electric field generator 30. The second plug 71 and the second socket 72 are push-button spring connectors, that is, the second connector 70 connects the adapter 20 and the electric field generator 30 by means of a connector. Each first connector 60, such as X1, Y1, X2 and Y2, is connected to the second connector 70 through a corresponding AC signal line 57. The first connectors 60, such as X1, Y1, X2 and Y2, are also connected to a corresponding set of grounding switches 54 and a corresponding set of analog-to-digital converters 52, respectively. Each first connector 60 is connected to the second connector 70 and the corresponding set of analog-to-digital converters 52 through a corresponding set of bidirectional switching switches 55. The second cable 25 has eight wires, including four wires 1 to 4 that are electrically connected to the corresponding AC signal lines 57 for transmitting AC signals, one wire 5 that is electrically connected to the data receiving line RX of the first communication unit 56, one wire 6 that is electrically connected to the data transmitting line TX of the first communication unit 56, one wire 7 that is electrically connected to the VCC power line of the first power module 58, and one wire 8 that is electrically connected to the GND line of the first power module 58. The second connector 70 is connected to the first communication unit 56 via the data receiving line RX and the data transmitting line TX. The VCC pin of the second connector 70 is connected to the VVC power line of the first power module 58, and the GND pin of the second connector 70 is connected to the GND line of the first power module 58 and grounded. The VCC pin of the second connector 70 is also connected to the corresponding group of voltage regulators 53 and the corresponding group of analog-to-digital converters 52 via the VCC power line of the first power module 58.

[0051] refer to Figure 5 and Figure 7The electric field generator 30 includes: a second power supply module 32, a second controller 37 electrically connected to the second power supply module 32, an AC signal generator 39 connecting both the second power supply module 32 and the second controller 37, a second communication unit 38 electrically connected to the second controller 37, and a set of AC signal switches 40 electrically connected to the AC signal generator 39. The VCC pin of the second connector 70 is also electrically connected to the VCC power line of the second power supply module 32, and the GND pin of the second connector 70 is grounded through the GND line of the second power supply module 32. The second power supply module 32 is also connected to and supplies power to the second controller 37 and the AC signal generator 39, respectively. The second communication unit 38 is electrically connected to the wire 5 of the second connector 70 through its data receiving line RX and to the wire 6 of the second connector 70 through its data transmitting line TX, thereby enabling information exchange between the electric field generator 30 and the adapter 20. The second controller 37 is also electrically connected to the second communication unit 38, the AC signal generator 39, and a set of AC signal switches 40. The second controller 37 is configured to control the opening and closing of each AC signal switch 40 in the set of AC signal switches 40 and adjust the relevant parameters of the AC signal applied by the AC signal generator 39 according to the relevant digital signals received from the adapter 20 by the second communication unit 38. The AC signal generator 39 is electrically connected to the wires 1 to 4 of the second connector 70 through the set of AC signal switches 40. The set of AC signal switches 40 includes multiple AC signal switches 40, and the multiple AC signal switches 40 are arranged one-to-one with multiple electrode plates 13. Each AC signal switch 40 is electrically connected to the corresponding wires 1, 2, 3, and 4 of the second connector 70 through an AC signal line 41-1, 41-2, 41-3, 41-4, and is also electrically connected to the corresponding electrode plate 13 through the corresponding wires 1, 2, 3, and 4 of the second connector 70 to transmit an AC signal to each electrode plate 13. The AC signal generator 39 is electrically connected to all AC signal switches 40-1, 40-2, 40-3, and 40-4 in the group of AC signal switches 40 via an AC signal line 41. Specifically, the number of AC signal switches 40 in the electric field generator 30 is related to the number of electrode plates 13. In this embodiment, the number of AC signal switches 40 and the number of electrode plates 13 are both four. The AC signal switches 40 include a first AC signal switch 40-1, a second AC signal switch 40-2, a third AC signal switch 40-3, and a fourth AC signal switch 40-4, which are electrically connected to the wires 1 to 4 of the second connector 70 respectively.One end of the first AC signal switch 40-1 is electrically connected to the AC signal generator 39, and the other end is electrically connected to the corresponding AC signal transmission wire 1 in the second connector 70 through an AC signal line 41-1, and then electrically connected to an AC signal line 57 in the adapter 20 corresponding to the corresponding electrode 13 through the wire 1 of the second connector 70, so as to transmit an AC signal to the electrode 13; one end of the second AC signal switch 40-2 is electrically connected to the AC signal generator 39, and the other end is electrically connected to the corresponding AC signal transmission wire 2 in the second connector 70 through an AC signal line 41-2, and then electrically connected to an AC signal line 57 in the adapter 20 corresponding to the corresponding electrode 13 through the wire 2 of the second connector 70, so as to transmit an AC signal to the electrode 13. One end of the third AC signal switch 40-3 is electrically connected to the AC signal generator 39, and the other end is electrically connected to the corresponding AC signal transmission wire 3 in the second connector 70 via an AC signal line 41-3, and then electrically connected to an AC signal line 57 in the adapter 20 corresponding to the corresponding electrode 13 via the wire 3 of the second connector 70, so as to transmit AC signals to the electrode 13. One end of the fourth AC signal switch 40-4 is electrically connected to the AC signal generator 39, and the other end is electrically connected to the corresponding AC signal transmission wire 4 in the second connector 70 via an AC signal line 41-4, and then electrically connected to an AC signal line 57 in the adapter 20 corresponding to the corresponding electrode 13 via the wire 4 of the second connector 70, so as to transmit AC signals to the electrode 13. The four AC signal lines 57 in the adapter 20 are electrically connected to their respective X1, Y1, X2, and Y2 ports, and transmit alternating electrical signals to the corresponding electrode 13 through the corresponding ports.

[0052] The following will refer to Figures 3 to 5 The working principle of the tumor electric field therapy device 100 in this embodiment is described in detail.

[0053] Specifically, when it is necessary to detect the temperature of each electrode unit 33 of a certain electrode plate 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each of the multiple bidirectional switching switches 55 of a set of bidirectional switching switches 55 electrically connected to the electrode plate 13 to turn on one end and turn off the other end, so as to disconnect the AC signal applied to the electrode plate 13; at the same time, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each of the grounding switches 54 of a set of grounding switches 54 electrically connected to the electrode plate 13 to turn on in sequence. At this time, the temperature detection signals collected by each temperature sensor 34 of each electrode unit 33 in each row of the electrode plate 13 can be collected in sequence in time through the multiple detection channels A, B, C, D, E of a set of analog-to-digital converters 52 corresponding to the electrode plate 13. Each detection channel A, B, C, D, and E of each group of analog-to-digital converters 52 simultaneously acquires only the temperature detection signal of the temperature sensor 34 of the corresponding electrode unit 33 in the same row of electrode plates 13. This temperature detection signal can be characterized by voltage values. Of the four grounding switches 54 corresponding to the electrode plate 13, only one can be on at any given time, while the other three are off. All five bidirectional switching switches 55 of the group of analog-to-digital converters 52 are switched to their respective terminals 1, so that each dual-purpose conductive trace 19 of the electrode plate 13 is electrically connected to the corresponding detection channels A, B, C, D, and E of the corresponding analog-to-digital converter 52. With this configuration, the group of analog-to-digital converters 52 can acquire the voltage values ​​of all temperature sensors 34 of each electrode unit 33 in the same row of electrode plates 33 that are shorted by one grounding trace 18 corresponding to the on-circuit grounding switch 54.

[0054] Specifically, when grounding switch 54-1 is closed, grounding switches 54-2, 54-3, and 54-4 are all open, and the first bidirectional switching switch 55-1, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3, the fourth bidirectional switching switch 55-4, and the fifth bidirectional switching switch 55-5 are all switched to their respective terminals 1, the temperature sensors 34 of electrode units 33-1 to 33-5 in the first row group are energized, while the temperature sensors 34 of electrode units 33-6 to 33-20 in the remaining rows are de-energized. Since electrode units 33-1, 33-6, 33-11, and 33-2 are short-circuited on the first detection channel A of the analog-to-digital converter 52 in this group... Each of the six temperature sensors 34 has a signal terminal 34-2. However, only the ground terminal 34-1 of the temperature sensor 34 in electrode unit 33-1 is connected to ground, while the ground terminals 34-1 of the temperature sensors 34 in electrode units 33-6, 33-11, and 33-16 are disconnected. Each electrode unit 33 has a diode 36 connected in series with the temperature sensor 34, which does not affect the resistance of the temperature sensor 34 in electrode unit 33-1. Therefore, only the temperature sensor 34 of electrode unit 33-1 is effectively operating on the first detection channel A of this group of analog-to-digital converters 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 34 in electrode unit 33-1. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 in electrode unit 33-2. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 in electrode unit 33-3. The voltage value acquired on the fourth detection channel D of the analog-to-digital converter 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-4. The voltage value acquired on the fifth detection channel E of the analog-to-digital converter 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-5.

[0055] When grounding switch 54-2 is closed, and grounding switches 54-1, 54-3, and 54-4 are all open, and the first bidirectional switching switch 55-1, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3, the fourth bidirectional switching switch 55-4, and the fifth bidirectional switching switch 55-5 are all switched to their respective terminals 1, the temperature sensors 34 of electrode units 33-6 to 33-10 in the second row are energized, while the temperature sensors 34 of electrode units 33-1 to 33-5 and electrode units 33-11 to 33-20 in the other rows are de-energized. Since electrode units 33-1, 33-6, and 33-11 are short-circuited on the first detection channel A of the analog-to-digital converter 52 in this group,... Each of the electrode units 33-16 has a signal terminal 34-2 for its temperature sensor 34. However, only the ground terminal 34-1 of the temperature sensor 34 in electrode unit 33-6 is connected to ground, while the ground terminals 34-1 of the temperature sensors 34 in electrode units 33-1, 33-11, and 33-16 are disconnected. Each electrode unit 33 has a diode 36 connected in series with the temperature sensor 34, which does not affect the resistance of the temperature sensor 34 in electrode unit 33-6. Therefore, only the temperature sensor 34 of electrode unit 33-6 is effectively operating on the first detection channel A of this group of analog-to-digital converters 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 34 in electrode unit 33-6. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 in electrode unit 33-7. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 in electrode unit 33-8. The voltage value acquired on the fourth detection channel D of the analog-to-digital converter 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-9. The voltage value acquired on the fifth detection channel E of the analog-to-digital converter 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-10.

[0056] When grounding switch 54-3 is closed, and grounding switches 54-1, 54-2, and 54-4 are all open, and the first bidirectional switching switch 55-1, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3, the fourth bidirectional switching switch 55-4, and the fifth bidirectional switching switch 55-5 are all switched to their respective terminals 1, the temperature sensors 34 of electrode units 33-11 to 33-15 in the third row are energized, while the temperature sensors 34 of electrode units 33-1 to 33-10 and electrode units 33-16 to 33-20 in the other rows are de-energized. Since electrode units 33-1, 33-6, and 33-11 are short-circuited on the first detection channel A of the analog-to-digital converter 52 in this group,... Each of the electrode units 33-16 has a signal terminal 34-2 for its temperature sensor 34. However, only the ground terminal 34-1 of the temperature sensor 34 in electrode unit 33-11 is connected to ground. The ground terminals 34-1 of the temperature sensors 34 in electrode units 33-1, 33-6, and 33-16 are disconnected. Each electrode unit 33 has a diode 36 connected in series with the temperature sensor 34, which does not affect the resistance of the temperature sensor 34 in electrode unit 33-11. Therefore, only the temperature sensor 34 in electrode unit 33-11 is effectively operating on the first detection channel A of this group of analog-to-digital converters 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 34 in electrode unit 33-11. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 in electrode unit 33-12. The voltage value acquired on the third detection channel C of this group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of electrode unit 33-13. The voltage value acquired on the fourth detection channel D of this group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of electrode unit 33-14. The voltage value acquired on the fifth detection channel E of this group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of electrode unit 33-15.

[0057] When grounding switch 54-4 is closed, and grounding switches 54-1, 54-2, and 54-3 are all open, and the first bidirectional switching switch 55-1, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3, the fourth bidirectional switching switch 55-4, and the fifth bidirectional switching switch 55-5 are all switched to their respective terminals 1, the temperature sensors 34 of electrode units 33-16 to 33-20 in the fourth row are energized, while the temperature sensors 34 of electrode units 33-1 to 33-15 in the other rows are de-energized. Since electrode units 33-1, 33-6, 33-11, and 33-16 are short-circuited on the first detection channel A of the analog-to-digital converter 52 in this group... The signal terminal 34-2 of the temperature sensor 34 is connected, but only the ground terminal 34-1 of the temperature sensor 34 in electrode unit 33-16 is grounded. The ground terminals 34-1 of the temperature sensors 34 in electrode units 33-1, 33-6, and 33-11 are disconnected. Each electrode unit 33 has a diode 36 connected in series with the temperature sensor 34, which does not affect the resistance of the temperature sensor 34 in electrode unit 33-16. Therefore, only the temperature sensor 34 in electrode unit 33-16 is effectively operating on the first detection channel A of this group of analog-to-digital converters 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 34 in electrode unit 33-16. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 in electrode unit 33-17. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 in electrode unit 33-18. The voltage value acquired on the fourth detection channel D of the analog-to-digital converter 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-19. The voltage value acquired on the fifth detection channel E of the analog-to-digital converter 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-20.

[0058] Therefore, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can acquire the temperature detection signals of the temperature sensors 34 of all electrode units 33 of a certain electrode plate 13 by controlling a set of bidirectional switching switches 55 and a set of grounding switches 54 that are electrically connected to a certain electrode plate 13. Similarly, the temperature detection signals of the temperature sensors 34 of each electrode unit 33 of other electrode plates 13 can be obtained.

[0059] The first controller 51, multiple sets of analog-to-digital converters 52, and multiple sets of bidirectional switching switches 55 can automatically perform operations through pre-programmed program code. For example, the first controller 51 first controls all bidirectional switching switches 55 in the corresponding set to switch to end 1, so that all ends 1 of these bidirectional switching switches 55 are turned on and all ends 2 are turned off, so that each dual-purpose conductive trace 19 of the corresponding electrode plate 13 is electrically connected to the corresponding set of analog-to-digital converters 52. Then, it closes the grounding switch 54-1 in the corresponding set of grounding switches 54 and opens the remaining grounding switches 54-2 to 54-4 in the set of grounding switches 54. During this period, the set of analog-to-digital converters 52... Each detection channel A, B, C, D, and E of the corresponding electrode 13 acquires the temperature detection signals of each temperature sensor 34 of each electrode unit 33 located in the first row group, converts them into digital signals, and stores them in a separately set memory. Then, after a preset interval, the first controller 51 closes ground switch 54-2 in the group of ground switches 54 and opens ground switches 54-1, 54-3, and 54-4 in the group of ground switches 54. During this period, each detection channel A, B, C, D, and E of the group of analog-to-digital converters 52 acquires the temperature detection signals of each temperature sensor 34 of each electrode unit 33 located in the second row group. By sequentially turning on each ground switch 54 in the group of ground switches 54 individually, the temperature detection signals of all temperature sensors 34 on the electrode 13 can be obtained. Similarly, through this operation, the temperature detection signals of all temperature sensors 34 on at least one pair of electrode 13 can be obtained.

[0060] When it is necessary to apply an AC signal to the patient through each electrode unit 33 of an electrode pad 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls all the grounding switches 54 in a set of grounding switches 54 corresponding to the electrode pad 13 to be disconnected, and at the same time controls all the bidirectional switching switches 55 in a set of bidirectional switching switches 55 corresponding to the electrode pad 13 to be switched to their respective 2 ends, so that all 1 ends of these bidirectional switching switches 55 are disconnected and all 2 ends are connected, so that each dual-purpose conductive trace 19 of the electrode pad 13 is electrically connected to an AC signal line 57 corresponding to the electrode pad 13 in the adapter 20, thereby transmitting the AC signal to each electrode unit 33 of the electrode pad 13. When the temperature detection signals of the temperature sensors 34 of all electrode units 33 of the detected electrode plate 13 are much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 through its second controller 37 to continue generating an AC signal with increased voltage or current amplitude, which is then transmitted to the corresponding counter electrode plate 13 through the corresponding AC signal line 57 of the adapter 20, so that the counter electrode plate 13 continues to apply an AC signal; when the temperature detection signals of the temperature sensors 34 of all electrode units 33 of the detected electrode plate 13 are lower than but close to the preset temperature threshold, the electric field generator 30 controls the AC signal generator 39 .... When the preset temperature threshold is stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the voltage or current of the AC signal generated by the AC signal generator 39 through the second controller 37, thereby reducing the voltage or current of the AC signal applied to the electrode pads 13. When the temperature detection signal of the temperature sensor 34 of an electrode unit 33 on a certain electrode pad 13 is detected to be greater than the preset temperature threshold, the electric field generator 30 controls the AC signal switch 40 electrically connected to the electrode pad 13 to disconnect through the second controller 37, so as to stop applying the AC signal to the electrode pad 13. In this way, the tumor electric field therapy device 100 controls the application of the AC signal based on the temperature detection signal, and dynamically adjusts the applied AC signal in real time based on the detected temperature to avoid low-temperature burns to the user.

[0061] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and not to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application, and they should all be covered within the scope of the claims and specification of this application. In particular, as long as there is no structural conflict, the various technical features mentioned in the embodiments can be combined in any way. This application is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A tumor electric field therapy device, comprising an electric field generator for generating alternating current signals and at least a pair of electrode plates electrically connected to the electric field generator, characterized in that, The electrode sheet includes a flexible circuit board and multiple electrode units spaced apart on the flexible circuit board. The multiple electrode units are divided into multiple row groups and multiple column groups in terms of circuit connection. The flexible circuit board is embedded with multiple ground traces corresponding to the multiple row groups and multiple dual-purpose signal lines corresponding to the multiple column groups. Each ground trace short-circuits the corresponding part of each electrode unit in the corresponding row group to ground. Each dual-purpose signal line short-circuits the corresponding part of each electrode unit in the corresponding column group and transmits AC signals to each electrode unit in the corresponding column group in a first mode, and transmits DC signals or temperature detection signals detected by each electrode unit in the corresponding column group in a second mode.

2. The tumor electric field therapy device according to claim 1, characterized in that, Each of the electrode units includes a transducer element for transmitting an AC signal and a temperature sensor for detecting and transmitting a temperature detection signal. The temperature sensor has a ground terminal shorted to the corresponding ground trace and a signal terminal shorted to the corresponding dual-purpose signal line. The transducer element is shorted to the corresponding dual-purpose signal line.

3. The tumor electric field therapy device according to claim 2, characterized in that, The grounding terminals of the temperature sensors of each electrode unit located in the same row group are all shorted to the same grounding trace.

4. The tumor electric field therapy device according to claim 2, characterized in that, The transducer elements of each electrode unit located in the same column are all shorted to the same dual-purpose signal line.

5. The tumor electric field therapy device according to claim 2, characterized in that, The signal terminals of the temperature sensors of each electrode unit located in the same column are all shorted to the same dual-purpose signal line.

6. The tumor electric field therapy device according to claim 1, characterized in that, All of the aforementioned grounding traces are disconnected when the dual-purpose signal lines transmit AC signals.

7. The tumor electric field therapy device according to claim 1, characterized in that, When the grounding traces are transmitting DC signals or temperature detection signals on the dual-purpose signal lines, only one of them is conducting while the others are disconnected.

8. The tumor electric field therapy device according to any one of claims 1 to 7, characterized in that, The electric field generator has a preset temperature threshold. When the temperature detection signal detected by the temperature sensor is much lower than the preset temperature threshold, the dual-purpose signal line transmits an AC signal with increased voltage or current amplitude to the corresponding electrode unit.

9. The tumor electric field therapy device according to claim 8, characterized in that, When the temperature detection signal detected by the temperature sensor is close to but still below the preset temperature threshold, the dual-purpose signal line transmits an AC signal with reduced voltage or current amplitude to the corresponding electrode unit.

10. The tumor electric field therapy device according to claim 8, characterized in that, The dual-purpose signal line stops transmitting AC signals to the electrode unit when the temperature detection signal detected by the temperature sensor exceeds the preset temperature threshold.

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