52 results about "Electric Field Therapy" patented technology

The invention provides a tumor electric field treatment system, an electrode slice temperature detection method and an electrode slice anomaly detection method, the system comprises an alternating current signal generator, an electrode slice and a controller, the electrode slice comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the plurality of electrode units are connected with the controller. The grounding ends of the temperature detection units in each row group are jointly connected to the same grounding wire, and the signal ends of the temperature detection units in each column group are connected to the same dual-purpose signal wire after being in short circuit with the corresponding electrode units; when the dual-purpose signal line is connected to the temperature sampling point, the grounding wires are sequentially conducted, so that temperature detection signals detected by the temperature detection units are sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, alternating electric signals are transmitted to the electrode units. Therefore, the temperature of the electrode plate can be detected by using fewer conductive traces, and whether the electrode plate is abnormal or not can be judged through temperature detection.

The invention provides an adapter and a tumor electric field treatment system, an electrode plate comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the grounding ends of the temperature detection units in each row group are connected to the same grounding wire. The signal end of each temperature detection unit in each column group is in short circuit with the corresponding electrode unit and then is connected to the same dual-purpose signal line; a bidirectional change-over switch of the adapter is configured to switch a dual-purpose signal line to be connected to a temperature sampling point or an alternating power line, and when the dual-purpose signal line is connected to the temperature sampling point, each grounding line is conducted in sequence so that a temperature detection signal detected by each temperature detection unit is sampled based on the temperature sampling point; and when the dual-purpose signal line is communicated with the alternating power line, an alternating current signal is transmitted to each electrode unit through the dual-purpose signal line, so that partition control and comprehensive temperature detection of the electrode plate are realized.

The invention provides an electrode plate and a tumor electric field treatment system, the electrode plate comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the grounding ends of the temperature detection units in each row group are connected to a grounding pin through a control switch. The signal end of each temperature detection unit in each column group is connected to a bidirectional change-over switch through a dual-purpose signal line after being respectively in short circuit with the corresponding electrode unit; when the dual-purpose signal lines are connected to the temperature sampling points, temperature detection signals detected by the corresponding temperature detection units in the corresponding column groups are respectively sampled based on the temperature sampling points by configuring the on-off states of the control switches; when the dual-purpose signal lines are connected to the alternating power lines, alternating electric signals are applied to the electrode units in the corresponding column groups based on the alternating power lines. In this way, a plurality of electrode units can be zoned and controlled using fewer conductive traces.

The invention provides an adapter and tumor electric field therapy, the tumor electric field therapy comprises an electrode plate, the electrode plate is provided with a flexible circuit board, a plurality of electrode units and a handshake chip used for handshake communication, and each electrode unit comprises a dielectric element and a temperature sensor with a signal end and a grounding end. The flexible circuit board is provided with multiple paths of grounding wires connected to the grounding ends and multiple paths of dual-purpose signal wires connected to the signal ends, and the dielectric elements of the electrode units are in short circuit with the signal ends. The adapter is provided with a plurality of grounding switches and a plurality of bidirectional change-over switches, each grounding wire is grounded through a corresponding grounding switch, and each dual-purpose signal wire is electrically connected with a corresponding bidirectional change-over switch. The number of the bidirectional change-over switches is greater than or equal to the number of the dual-purpose signal lines and / or the number of the grounding switches is greater than or equal to the number of the grounding lines. The bidirectional change-over switch connects the dual-purpose signal line to an AC signal line so as to transmit an AC electric signal or a detection channel of the analog-to-digital converter so as to transmit a temperature signal of each temperature sensor.

A medical instrument is used for a device, a system and application of digestive tract electric field treatment and comprises a long and thin rod, a sleeve and an expandable component, the expandable component comprises a plurality of supporting rods and an electrode array film, when the long and thin rod slides forwards to a front limit position relative to the sleeve, the expandable component is in a contraction working state, and when the electrode array film slides forwards to a rear limit position relative to the sleeve, the expandable component is in a contraction working state. Each supporting rod is tightly attached to the outer surface of the slender rod; when the slender rod slides backwards relative to the sleeve from the front limit position, the expandable component is in an expanded working state, the front section supporting rods and the rear section supporting rods are in an unfolded umbrella shape, and the electrode array film is in an unfolded state. The device is used for ablating tissues of the alimentary canal and treating diseases such as diabetes mellitus and obesity.

The invention provides an electric field treatment system and an electrode patch thereof. The electrode patch comprises a backing, a transducer array pasted on the backing and a pasting piece pasted on the transducer array. The transducer array comprises a plurality of electrode units and a plurality of connecting parts for connecting two adjacent electrode units, and the transducer array comprises a left side part and a right side part which are symmetrically arranged left and right. The overall outer contours of the left side part and the right side part are in a half-water-drop shape, and each of the left side part and the right side part comprises a plurality of electrode units which are arranged at intervals from top to bottom. Each electrode unit comprises a main body part, a conducting strip located on the main body part and a dielectric layer covering the conducting strip. According to the electric field treatment system, the electrode patch and the transducer array thereof, the water-drop-shaped outer contour is adopted, the electrode units arranged at intervals are included, the relative position of each electrode unit can be properly adjusted, the pasting performance is better, in addition, a dielectric layer is adopted to replace a ceramic chip, the dead weight of the electrode patch is reduced, and pasting comfort is provided.

The invention provides a tumor electric field treatment system, which comprises a first pair of insulated electrodes and a second pair of insulated electrodes which are respectively configured on the surface of the trunk of a patient; the control signal generator generates a periodic control signal with a first output state and a second output state, the first output state has a first time period T1, the second output state has a second time period T2, and the first time period T1 and the second time period T2 are both between 700 ms and 980 ms; and an AC signal generator that generates a first AC signal having a frequency of 150 kHz between the first pair of insulated electrodes when the control signal is in a first output state, and generates a second AC signal having a frequency of 150 kHz between the second pair of insulated electrodes when the control signal is in a second output state, switching between the first output state and the second output state. According to the tumor electric field treatment system, through switching between the first output state and the second output state, the better effect of inhibiting tumor cell proliferation is achieved.

This application provides a tumor electric field therapy system and an electrode quality inspection method. The system includes an electrode sheet, each electrode sheet comprising multiple electrode units and multiple temperature detection units. The multiple electrode units are divided into multiple row groups and multiple column groups. The grounding terminals of each temperature detection unit in each row group are short-circuited to the same grounding line. The signal terminals of each temperature detection unit in each column group are short-circuited to the corresponding electrode unit and then connected to the same dual-purpose signal line. In this way, an electric field generator or adapter can use fewer conductive traces to control the multiple electrode units in zones and sample the temperature detection signals, and the quality of the electrode sheet can be inspected based on the sampled temperature detection signals.

The invention provides a tumor electric field treatment system and an electrode thereof, the electrode comprises an electrode array, the electrode array comprises a substrate and a plurality of temperature sensors arranged on the substrate, the substrate is provided with a plurality of main body parts and a plurality of connecting strips connecting two adjacent main body parts, and the plurality of temperature sensors are selectively arranged on part of the main body parts. Each temperature sensor is provided with a grounding end and a signal end, the plurality of main body parts have different areas, the main body parts with the largest area and the smallest area are respectively provided with the temperature sensors, conducting strips are arranged on the front surfaces of the main body parts, AC wires for transmitting AC electric signals are arranged on the front surfaces of the connecting strips, and the AC wires are electrically connected with the corresponding conducting strips; the back surface of the substrate is provided with a grounding wire used for being connected with a grounding end and a signal wire used for being connected with a signal end. By reasonably setting the positions and the number of the temperature sensors, the wiring difficulty is reduced, the projection overlapping area of the AC line and the signal line is reduced, and mutual crosstalk of AC electric signals and temperature measurement signals is avoided.

Combination therapies for the treatment of cancers are provided. In some aspects, a nucleic acid encoding a transdifferentiation determinant is administered in combination with a chemotherapeutic, electric fields therapy (e.g., TTField), or electromagnetic fields therapy to synergistically treat a cancer such as a glioma or glioblastoma (GBM).

This invention relates to a device for electric field therapy of the human digestive tract, comprising: an inner guide rod, an outer sleeve, a rotating ring, and a supporting component, with an electrode array membrane spirally wound around the supporting component. When the supporting component is in a radially contracted state, the invention can be placed within the surgical instrument channel of a commonly used gastroscopy. When the supporting component is in a radially expanded state, it supports the electrode array membrane, enabling accurate electric field therapy of the upper digestive tract, particularly the inner wall of the duodenum.

The invention belongs to the technical field of gene application and tumor treatment, and particularly relates to a personalized tumor electric field treatment system and method based on DAPK2 gene feedback regulation. The invention provides the application of the expression of the DAPK2 gene as a marker for optimizing tumor electric field treatment parameters, and the tumor electric field treatment parameters are optimized and adjusted by utilizing the expression change condition of the DAPK2 gene. The invention further provides a tumor electric field treatment parameter optimization device. The tumor electric field treatment parameter optimization device comprises a clinical biopsy detection unit, a treatment parameter control unit, a data processing unit and the like. Through a dynamic feedback regulation mechanism, optimization of personalized tumor electric field treatment is realized, the treatment effect is ensured to be maximized, side effects are reduced, and the life quality of a patient is improved.

The application provides an implantable electrode and an electric field treatment device for intracranial tumor treatment. The implantable electrode for intracranial tumor treatment comprises a flexible electrode, the flexible electrode comprises a flexible base layer and at least one electrode unit arranged on the flexible base layer, at least one end of the flexible base layer is not covered by the electrode unit, and an extension section is formed at the part of the flexible base layer not covered by the electrode unit. The electric field treatment device comprises a control module and the implantable electrode, the control module and the flexible electrode of the implantable electrode are electrically connected to generate an alternating electric field. The flexible electrode can be attached to the surface of a tumor cavity by surface adhesion, and the extension section can extend out of the tumor cavity and be attached to the surface of brain tissue, so that the flexible electrode can be stably fixed in the body. Therefore, the targeting of tumor electric field treatment can be obviously improved, the stability of the electric field in the related area can be improved, the compliance of the patient can be improved, adverse reactions can be reduced, and the treatment effect can be improved as a whole.

The invention provides a tumor electric field treatment system which comprises an electrode plate and a controller, the electrode plate comprises a plurality of electrode units and a handshake chip, and each electrode unit comprises a dielectric element and a temperature sensor with a signal end and a grounding end. The plurality of electrode units are arranged in at least two rows and two columns on the circuit, the grounding ends of the temperature sensors in the same row are in short circuit through the same path of grounding wire, and the signal ends of the temperature sensors in the same column group are in short circuit through the same path of dual-purpose signal wire. The dual-purpose signal line is configured to transmit an alternating current signal to the corresponding dielectric element in a first mode, and transmit a direct current signal or a temperature signal detected by the corresponding temperature sensor to the signal end of the corresponding temperature sensor in a second mode. The controller is configured to communicate with the handshake chip so as to judge the connection state of the electrode slices, and is configured to combine and control the states of the grounding wire and the dual-purpose signal line when the electrode slices are normally connected so as to enable the dual-purpose signal line to be switched between transmission of an alternating current electric signal and transmission of a temperature detection signal.

1. The name of the design product: electrode sheet. 2. The use of the design product: the product is used to match the electric field therapy instrument or other physiotherapy instrument output electric field signal. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: design 1 perspective view. 5. Design 1 is designated as the basic design. 6. The cable part of the product of design 1 to design 6 is not fixed length, the length adopts the omission drawing method; the part indicated by A in the perspective view of design 1 is transparent material; the outer layer of the part indicated by B in the perspective view of design 2 is transparent material; the outer layer of the part indicated by C in the perspective view of design 3 is transparent material; the part indicated by D in the perspective view of design 4 is transparent material; the outer layer of the part indicated by E in the perspective view of design 5 is transparent material; the outer layer of the part indicated by F in the perspective view of design 6 is transparent material.

Devices are provided having human anatomical dimensions, regardless of materials made, that can deliver iEF therapy for treatment of cancer. For instance, aspects can be implemented as a wearable device for treating solid tumors. The device includes a coil of electrically conductive material supported by the wearable garment. Further, the wearable device includes a controller electrically coupled to the coil to produce an induced field for therapy.

Provided in the present application are an electric field therapy system and an electrode patch. The electrode patch comprises a backing, an electrode array and several adhesive members, wherein the electrode array comprises several electrode units and several connecting portions connecting two adjacent electrode units; the front side of each electrode unit is provided with a conductive sheet, the front side of each connecting portion is provided with an AC wire, and the AC wire is connected to and in conduction with the conductive sheets of the electrode units that are respectively located on two ends of the connecting portion; and the several electrode units are divided into a plurality of electrode unit groups, each electrode unit group is jointly formed by two adjacent electrode units and the connecting portion connecting the two electrode units, the electrode array further comprises dielectric layers disposed corresponding to the electrode unit groups, and each dielectric layer directly covers and conductively connects the two conductive sheets in the respective electrode unit groups and the respective AC wire. In the electrode patch of the present application, every two adjacent electrode units are formed into an electrode unit group by means of a dielectric layer, and when an electrical performance test is performed on the electrode patch, the test is performed in units of electrode unit groups, so that the test efficiency can be improved.

The invention provides a tumor electric field treatment system which comprises at least one pair of electrode plates and an electric field generator, each electrode plate is provided with a flexible circuit board, a plurality of electrode units and a handshake chip, and each electrode unit comprises a dielectric element and a temperature sensor with a signal end and a grounding end. The flexible circuit board is provided with multiple paths of grounding wires connected to the grounding ends and multiple paths of dual-purpose signal wires connected to the signal ends, and the dielectric elements of the same electrode unit are in short circuit with the signal ends. The electric field generator sends a handshake signal to the handshake chip, the handshake chip sends a feedback signal to the electric field generator after receiving the handshake signal, and the electric field generator transmits an alternating current signal to each dielectric element through each dual-purpose signal line in a first mode after receiving the feedback signal; in the second mode, direct current signals or temperature signals detected by the temperature sensors are transmitted to the signal ends through the dual-purpose signal lines, and the grounding lines are in an off state in the first mode and are in an on state in the second mode.

The invention provides a tumor electric field treatment system which comprises at least one pair of electrode plates and an electric field generator, each electrode plate is provided with a flexible circuit board, a plurality of electrode units and a handshake chip, and each electrode unit comprises a dielectric element and a temperature sensor with a signal end and a grounding end. The flexible circuit board is provided with multiple paths of grounding wires connected to the grounding ends and multiple paths of dual-purpose signal wires connected to the signal ends, and the dielectric elements of the same electrode unit are in short circuit with the signal ends. The electric field generator sends a handshake signal to the handshake chip, the handshake chip sends a feedback signal to the electric field generator after receiving the handshake signal, and the electric field generator transmits an alternating current signal to each dielectric element through each dual-purpose signal line in a first mode after receiving the feedback signal; in the second mode, direct current signals or temperature signals detected by the temperature sensors are transmitted to the signal ends through the dual-purpose signal lines, and the grounding lines are in an off state in the first mode and are in an on state in the second mode.

A computer-implemented method includes: obtaining a three-dimensional model of a subject; identifying radiation therapy regions in the model to deliver radiation therapy to a tumor of the subject, the radiation therapy regions including first and second radiation therapy regions for receiving first and second doses, respectively, of radiation therapy; identifying a tumor therapy electric field therapy region in the model to deliver tumor therapy electric field therapy to the tumor, the tumor therapy electric field therapy region including the first radiation therapy region; identifying a first dose of the tumor therapy electric field therapy for the first radiation therapy region to compensate for the first dose of radiation therapy being less than the second dose of radiation therapy; and selecting one or more transducer layouts to deliver a tumor therapy electric field to the subject based on the first dose of the tumor therapy electric field therapy for the first radiation therapy region.

1. The name of the design product: electrode sheet. 2. The use of the design product: the product is used to match the electric field therapy instrument or other physiotherapy instrument output electric field signal. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: design 1 perspective view 1. 5. Design 1 is designated as the basic design. 6. Other circumstances that need to be explained: the cable part of the product of design 1 to design 6 is an elongated object, the length adopts the omission drawing method; the part indicated by A in design 1 perspective view 1 is transparent material; the outer layer of the part indicated by B in design 2 perspective view 1 is transparent material; the outer layer of the part indicated by C in design 3 perspective view 1 is transparent material; the part indicated by D in design 4 perspective view 1 is transparent material; the outer layer of the part indicated by E in design 5 perspective view 1 is transparent material; the outer layer of the part indicated by F in design 6 perspective view 1 is transparent material.

This invention discloses a tumor electric field therapy device and system. The tumor electric field therapy device consists of a frame and electrode modules. The frame forms the skeleton structure of the therapy device, and the electrode modules are attached to the frame. Each electrode module has several electrode contacts, and each electrode contact can be either an active or passive contact. The active contacts can form a circuit with a radio frequency generation module. When the therapy device is implanted into the tumor resection site, all electrode contacts become active contacts, and each electrode contact forms a circuit with the radio frequency generation module, distinguishing between normal tissue and diseased tissue. After distinguishing between normal tissue and diseased tissue, the electrode contacts in the normal tissue area become passive contacts, and the electrode contacts in the diseased tissue area become active contacts, enabling targeted treatment of the diseased tissue and thus reducing the side effects of electric field therapy.

A method for improving electric field therapy administered to a patient having a tumor, wherein regimen parameters are selected for characteristics of the tumor. Methods of electric field therapy, methods of treating tumors using electric field therapy, and devices programmed to give an electric field therapy regimen are also described.

The application provides a tumor electric field treatment system and an alternating electric signal application method, which are used for applying an alternating electric field to a tumor part of a human body. The system comprises an electric field treatment device and at least two pairs of electrodes electrically connected to the electric field treatment device. The electric field treatment device cyclically and alternately outputs AC voltages to each pair of electrodes. One cycle is defined as one time of outputting an AC voltage to each pair of electrodes by the electric field treatment device. The peak-to-peak voltage in each cycle is a specific voltage. The electric field treatment device is provided with an initial voltage V c and a maximum specific voltage for the AC voltage output to each pair of electrodes. When the electric field treatment device starts to work, the AC voltage output to each pair of electrodes is increased from the initial voltage to the maximum specific voltage by a voltage increasing step △V in a preset total voltage increasing time T0. The tumor electric field treatment system of the application can avoid the generation of electric stimulation and prevent the patient from feeling uncomfortable during treatment.

The invention provides a tumor electric field treatment system, which comprises an electrode plate and a controller, the electrode plate comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the grounding ends of the temperature detection units in each row group are jointly connected to the same grounding wire. The signal end of each temperature detection unit in each column group is in short circuit with the corresponding electrode unit and then is connected to the same dual-purpose signal line; a direct current signal or an alternating current signal can be accessed to the dual-purpose signal line, and when the direct current signal is accessed to the dual-purpose signal line, all the grounding wires are sequentially conducted so that temperature detection signals detected by all the temperature detection units can be collected line by line; when the dual-purpose signal line is connected with an alternating-current electric signal, the alternating-current electric signal is transmitted to each electrode unit. In this way, temperature detection and zone control can be performed on the electrode plate by using fewer conductive traces.

This application provides an electric field generator, a tumor electric field therapy system, and a method for detecting the quality of electrode pads. The system includes an electrode pad, each electrode pad comprising multiple electrode units and multiple temperature detection units. The multiple electrode units are divided into multiple row groups and multiple column groups. The grounding terminals of each temperature detection unit in each row group are connected to a grounding pin via a control switch. The signal terminals of each temperature detection unit in each column group are shorted to their respective electrode units and then connected to a bidirectional switching switch via a dual-purpose signal line. Thus, multiple electrode units can be controlled in zones and temperature detection signals can be sampled using fewer conductive traces. Furthermore, based on the sampled temperature detection signals, it is possible to monitor whether the electrode pad is damaged or unqualified.

The application provides a tumor treatment electric field system, which comprises an electric field treatment instrument and multiple pairs of insulated electrodes electrically connected with the electric field treatment instrument, the electric field treatment instrument comprises an MCU control unit, an inverter voltage boost control unit electrically connected with the MCU control unit, a DC power supply control unit electrically connected with the MCU control unit and the inverter voltage boost control unit, an AC voltage control unit electrically connected with the inverter voltage boost control unit, and a direction control unit electrically connected with the MCU control unit and used for controlling the on and off of the AC voltage control unit and the corresponding pair of insulated electrodes, the electric field treatment instrument further has an alternating electric signal direction switching period, the MCU control unit is configured to control the on and off of the communication between the MCU control unit and the DC power supply control unit and whether to output a direct current electric signal to the inverter voltage boost control unit according to the alternating electric signal direction switching period.

1. The name of the design product: electrode sheet (No. 5). 2. The use of the design product: used for matching electric field therapy instrument or other physiotherapy instrument output electric field signal. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: front view. 5. The design contains colors.

The invention provides an electrode patch and an electric field treatment system.The electrode patch is provided with an electrode array used for applying a tumor electric field, the electrode array comprises a plurality of electrode units of different shapes, and at least one electrode unit is provided with a temperature detection unit and a stretching layer used for positioning the temperature detection unit; and the stretching layers divide the corresponding electrode units into a plurality of conductive regions with different areas. An electrode patch is divided into a plurality of electrode units in different shapes to adapt to attachment of different body surface skin positions, and part of the electrode units are provided with stretching layers to further divide the corresponding electrode units into a plurality of conductive areas in different areas to disperse heat accumulation of the corresponding electrode units. And the duration of applying the therapeutic electric field by the electrode patch is prolonged.

The invention provides an adapter, a tumor electric field treatment system, an electrode slice temperature detection method and an electrode slice overtemperature detection method. The adapter is electrically connected with the electrode plate, the electrode plate comprises a flexible circuit board and a plurality of electrode units which are arranged on the flexible circuit board and are arranged in multiple rows and multiple columns in a circuit, each electrode unit is provided with a dielectric element and a temperature sensor, and the flexible circuit board is provided with multiple paths of grounding wires and multiple paths of dual-purpose signal wires. Each grounding wire is in short circuit connection with the grounding end of each temperature sensor in the corresponding row, and each dual-purpose signal wire is connected with the dielectric element of each electrode unit in the corresponding column and the signal end of each temperature sensor. The adapter is provided with a plurality of grounding switches which are respectively connected with the grounding wires in series and a plurality of bidirectional change-over switches which are respectively connected with the dual-purpose signal wires in series. The dual-purpose signal line is connected to an alternating-current electric signal or a direct electric signal in a switching mode through the bidirectional change-over switch so that the electrode unit can be switched between a first mode of applying the alternating-current electric signal and a second mode of detecting or collecting temperature.