99 results about "Electric Field Therapy" patented technology

The invention provides a tumor electric field treatment system, an electrode slice temperature detection method and an electrode slice anomaly detection method, the system comprises an alternating current signal generator, an electrode slice and a controller, the electrode slice comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the plurality of electrode units are connected with the controller. The grounding ends of the temperature detection units in each row group are jointly connected to the same grounding wire, and the signal ends of the temperature detection units in each column group are connected to the same dual-purpose signal wire after being in short circuit with the corresponding electrode units; when the dual-purpose signal line is connected to the temperature sampling point, the grounding wires are sequentially conducted, so that temperature detection signals detected by the temperature detection units are sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, alternating electric signals are transmitted to the electrode units. Therefore, the temperature of the electrode plate can be detected by using fewer conductive traces, and whether the electrode plate is abnormal or not can be judged through temperature detection.

The invention provides an adapter and a tumor electric field treatment system, an electrode plate comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the grounding ends of the temperature detection units in each row group are connected to the same grounding wire. The signal end of each temperature detection unit in each column group is in short circuit with the corresponding electrode unit and then is connected to the same dual-purpose signal line; a bidirectional change-over switch of the adapter is configured to switch a dual-purpose signal line to be connected to a temperature sampling point or an alternating power line, and when the dual-purpose signal line is connected to the temperature sampling point, each grounding line is conducted in sequence so that a temperature detection signal detected by each temperature detection unit is sampled based on the temperature sampling point; and when the dual-purpose signal line is communicated with the alternating power line, an alternating current signal is transmitted to each electrode unit through the dual-purpose signal line, so that partition control and comprehensive temperature detection of the electrode plate are realized.

The invention provides an electrode plate and a tumor electric field treatment system, the electrode plate comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the grounding ends of the temperature detection units in each row group are connected to a grounding pin through a control switch. The signal end of each temperature detection unit in each column group is connected to a bidirectional change-over switch through a dual-purpose signal line after being respectively in short circuit with the corresponding electrode unit; when the dual-purpose signal lines are connected to the temperature sampling points, temperature detection signals detected by the corresponding temperature detection units in the corresponding column groups are respectively sampled based on the temperature sampling points by configuring the on-off states of the control switches; when the dual-purpose signal lines are connected to the alternating power lines, alternating electric signals are applied to the electrode units in the corresponding column groups based on the alternating power lines. In this way, a plurality of electrode units can be zoned and controlled using fewer conductive traces.

Treatment of damaged, diseased, abnormal, obstructive, cancerous or undesired tissue (e.g. a tumor, a benign tumor, a malignant tumor, a cyst, or an area of diseased tissue, etc) is provided by delivering specialized pulsed electric field (PEF) energy to target tissue areas in a specific dose so as to obtain a superior outcome. The PEF energy and delivery has been optimized to provide advanced treatment of target tissue areas, including destruction of undesired tissue and generation of improved inflammatory and immune responses. These various types of treatment are controlled by a variety of factors including the electrode geometry, the dose of PEF energy delivered, the time the energy is delivered over, and the waveform of the PEF energy itself. The PEF energy is delivered in the form a dose which is considered to be one application of the specialized energy. Each dose creates a lesion in the target tissue area.

A system may include a processor-based system including at least one processor and memory comprising instructions. When executed by the processor-based system, the instructions cause the processor-based system to: access metrics of a subject who is being treated with a therapy that includes a magnetic non-parallel electric field (MNPEF) therapy or a magnetic non-parallel magnetic field (MNPMF) therapy, wherein the accessed metrics include at least one analyte, the at least one analyte including one or more of blood glucose data, lactate data, or pyruvate data, free fatty acid data, cholesterol data, and compliance data for complying with the therapy; use the accessed metrics as an input to a machine learning algorithm that is configured to determine a set of therapy parameters for the therapy, and program a controller operably connected to at least one energy field system to deliver the therapy according to the determined set of therapy parameters.

The present invention discloses an electric field enhancement guidance system based on the human body's natural cavities, comprising: an electric field guidance component for guiding the electric field of an external electrode deep into the human body; the electric field guidance component comprising a field-guiding electrode partially positioned within the human body's natural cavities and a field-guiding body, the field-guiding electrode being located at one end of the field-guiding body proximal to the human body's natural cavities; the field-guiding electrode comprising a field-guiding electrode body and a connecting electrode located at an end of the field-guiding body opposite the field-guiding electrode and proximal to the outer end of the human body's natural cavities; one or more second auxiliary electrodes positioned on the surface of human skin; the connecting electrode and the second auxiliary electrodes cooperating to form an electric field system. Also disclosed is the application of the electric field enhancement guidance system based on the human body's natural cavities in a tumor electric field therapy device. By utilizing the human body's natural cavities, the electric field is guided to a desired location within the body, resulting in a non-invasive treatment with improved therapeutic effects. The system is also larger in size, lacks a noticeable tip, and provides a larger heat distribution surface, preventing localized overheating and improving patient tolerance.

The utility model provides a tumor electric field treatment device and an electrode patch thereof, the electrode patch comprises an electrode array and one or more pasting pieces, and the electrode array is provided with a plurality of electrode units, a plurality of connecting parts for connecting two adjacent electrode units and a wiring part. The pasting piece is provided with a first layer covering the electrode array and a second layer used for being pasted to the body surface of a patient, and the viscosity of the first layer is larger than that of the second layer. According to the tumor electric field treatment device and the electrode patch thereof, the stickiness of the first layer covering the electrode array is higher than that of the second layer attached to the body surface of the patient, the electrode array can be tightly attached to the body surface of the patient without a backing, and the heat dissipation effect of the electrode patch attached to the body surface of the patient can be improved; and the sticking piece can be prevented from being separated from the electrode array when the electrode patch is removed from the body surface of the patient.

1. The name of this design product: Tumor electric field therapy device host. 2. Purpose of this design product: used for electric field therapy of tumors. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: Stereoscopic drawing 1.

The invention provides an adapter and tumor electric field therapy, the tumor electric field therapy comprises an electrode plate, the electrode plate is provided with a flexible circuit board, a plurality of electrode units and a handshake chip used for handshake communication, and each electrode unit comprises a dielectric element and a temperature sensor with a signal end and a grounding end. The flexible circuit board is provided with multiple paths of grounding wires connected to the grounding ends and multiple paths of dual-purpose signal wires connected to the signal ends, and the dielectric elements of the electrode units are in short circuit with the signal ends. The adapter is provided with a plurality of grounding switches and a plurality of bidirectional change-over switches, each grounding wire is grounded through a corresponding grounding switch, and each dual-purpose signal wire is electrically connected with a corresponding bidirectional change-over switch. The number of the bidirectional change-over switches is greater than or equal to the number of the dual-purpose signal lines and / or the number of the grounding switches is greater than or equal to the number of the grounding lines. The bidirectional change-over switch connects the dual-purpose signal line to an AC signal line so as to transmit an AC electric signal or a detection channel of the analog-to-digital converter so as to transmit a temperature signal of each temperature sensor.

A medical instrument is used for a device, a system and application of digestive tract electric field treatment and comprises a long and thin rod, a sleeve and an expandable component, the expandable component comprises a plurality of supporting rods and an electrode array film, when the long and thin rod slides forwards to a front limit position relative to the sleeve, the expandable component is in a contraction working state, and when the electrode array film slides forwards to a rear limit position relative to the sleeve, the expandable component is in a contraction working state. Each supporting rod is tightly attached to the outer surface of the slender rod; when the slender rod slides backwards relative to the sleeve from the front limit position, the expandable component is in an expanded working state, the front section supporting rods and the rear section supporting rods are in an unfolded umbrella shape, and the electrode array film is in an unfolded state. The device is used for ablating tissues of the alimentary canal and treating diseases such as diabetes mellitus and obesity.

This invention relates to a device for electric field therapy of the digestive tract, comprising a catheter, a support, an electrode array membrane, and a pulse generator; the pulse generator includes a current sensor for sensing the current flowing through the electrode pairs; during an initial time period, in a first sequence of pulse waves, the voltage amplitude of subsequent pulses is greater than the voltage amplitude of preceding pulses, and the current sensor senses a current equal to or exceeding a lower limit value I of a set range. S(MIN) At that time, in the next time period, the absolute value U of the voltage amplitude of each pulse of the second sequence pulse wave S Equal. This invention controls the output voltage amplitude of the pulse generator through feedback from a current sensor, making treatment safer for the human body.

The present application provides a tumor electric field therapy system, an adapter, and a tumor treatment device. The system includes at least one pair of electrode sheets, each of which includes multiple electrode units and multiple temperature detection units corresponding to the multiple electrode units. The multiple electrode units are divided into row groups and column groups. The temperature detection units in each row group are connected in series and are correspondingly provided with a rectifier switching unit. The adapter includes multiple groups of control switches, multiple groups of temperature sampling points, and multiple multiplexing switching units corresponding to the multiple electrode sheets. The number of control switches in each group is equal to the number of column groups of the corresponding electrode sheet. The ground terminals of the temperature detection units in each column group of the corresponding electrode sheet are grounded via the control switches. The number of temperature sampling points in each group is equal to the number of row groups of the corresponding electrode sheet. The multiplexing switching unit is connected to the corresponding rectifier switching unit via the dual-purpose signal line of the corresponding electrode sheet and is configured to switch the dual-purpose signal line of the corresponding electrode sheet to the temperature sampling point or the alternating power line of the corresponding group.

1. Name of the product in this design: Electrode Array. 2. Purpose of this design: This product is used to transmit electrical signals in conjunction with electric field therapy equipment or other physiotherapy equipment. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The invention relates to the technical field of tumor electric field treatment, and discloses a tumor electric field treatment system and a power supply switching device.The tumor electric field treatment system comprises a plurality of power supply devices and a load, and each power supply device is suitable for supplying power to the load so as to apply an alternating electric field to the tumor part of the human body; the power supply switching device comprises a plurality of power supply input ends and a power supply output end, each power supply input end in the plurality of power supply input ends is connected with the power supply end of the corresponding power supply device, and the power supply output end is connected with the load; the power supply switching circuit is configured to communicate one of the plurality of power supply input ends with the power supply output end based on the power supply voltage of each power supply device, so that the plurality of power supply devices are seamlessly switched to supply power to the load, and the power supply is ensured not to be interrupted; the effective treatment electric field duration of the tumor electric field therapeutic apparatus applied to the tissue area of the tumor is improved, and the treatment effect is improved.

The present invention discloses a high-frequency electrotherapy protection device and method. This device can directly sample data from the treatment circuit, providing direct data support for treatment efficacy. This allows for differentiated treatment of different treatment sites, enabling precise, quantified treatment of diseased areas, ensuring both treatment effectiveness and accuracy. It also enables early prediction of treatment mishaps, providing dual protection against potential safety hazards. The device comprises a high-frequency electric field therapy unit, a treatment energy monitoring unit, and a control unit.

1. The name of the design product: implantable electrode device. 2. The use of the design product: the design product is used for intracranial tumor electric field therapy. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view. 5. The rear view is the same as the front view, and the rear view is omitted; the left view is the same as the front view, and the left view is omitted; the right view is the same as the front view, and the right view is omitted.

The invention provides an electric field treatment system and an electrode patch thereof. The electrode patch comprises a backing, a transducer array pasted on the backing and a pasting piece pasted on the transducer array. The transducer array comprises a plurality of electrode units and a plurality of connecting parts for connecting two adjacent electrode units, and the transducer array comprises a left side part and a right side part which are symmetrically arranged left and right. The overall outer contours of the left side part and the right side part are in a half-water-drop shape, and each of the left side part and the right side part comprises a plurality of electrode units which are arranged at intervals from top to bottom. Each electrode unit comprises a main body part, a conducting strip located on the main body part and a dielectric layer covering the conducting strip. According to the electric field treatment system, the electrode patch and the transducer array thereof, the water-drop-shaped outer contour is adopted, the electrode units arranged at intervals are included, the relative position of each electrode unit can be properly adjusted, the pasting performance is better, in addition, a dielectric layer is adopted to replace a ceramic chip, the dead weight of the electrode patch is reduced, and pasting comfort is provided.

The present invention relates to a device for performing electric field therapy on the digestive tract. The device comprises a support, an electrode array membrane, and a pulse generator. The electrodes are coupled to the pulse generator via electrode leads embedded in the membrane body. A heating wire is also embedded in the membrane body and coupled to the pulse signal output terminal of the pulse generator via heating wire leads embedded in the membrane body. On the electrode array membrane, there is at least one electrical connection point between the heating wire and the electrodes, and the voltage signal between the heating wire lead and the electrode lead serves as a temperature sensing signal. The present invention combines a temperature sensing circuit with an electric heating circuit, resulting in a simple circuit and a reduced number of leads on the electrode array membrane.

The invention provides a tumor electric field treatment system, which comprises a first pair of insulated electrodes and a second pair of insulated electrodes which are respectively configured on the surface of the trunk of a patient; the control signal generator generates a periodic control signal with a first output state and a second output state, the first output state has a first time period T1, the second output state has a second time period T2, and the first time period T1 and the second time period T2 are both between 700 ms and 980 ms; and an AC signal generator that generates a first AC signal having a frequency of 150 kHz between the first pair of insulated electrodes when the control signal is in a first output state, and generates a second AC signal having a frequency of 150 kHz between the second pair of insulated electrodes when the control signal is in a second output state, switching between the first output state and the second output state. According to the tumor electric field treatment system, through switching between the first output state and the second output state, the better effect of inhibiting tumor cell proliferation is achieved.

The present invention relates to the field of medical instrument technology, and specifically to equipment and circuits for electrical stimulation and electric field therapy. The circuit includes a DC unit for providing a reference voltage to an AC / DC unit; the AC / DC unit is connected to a controller and an electrode, respectively; a feedback unit is connected to the AC / DC unit and the controller, respectively, for feeding back an electrical signal from the AC / DC unit to the controller; the controller is configured to adjust the reference voltage based on the electrical signal when the circuit operates in a first mode for electrical stimulation; and is further configured to adjust the drive signal of the AC / DC unit based on the electrical signal when the circuit operates in a second mode for electric field therapy. The objects adjusted vary depending on the operating mode of the circuit for electrical stimulation and electric field therapy, ensuring high-precision current control, thereby enabling applications of head and muscle electrical stimulation and electric field therapy with high current control accuracy.

This application provides a tumor electric field therapy system and an electrode quality inspection method. The system includes an electrode sheet, each electrode sheet comprising multiple electrode units and multiple temperature detection units. The multiple electrode units are divided into multiple row groups and multiple column groups. The grounding terminals of each temperature detection unit in each row group are short-circuited to the same grounding line. The signal terminals of each temperature detection unit in each column group are short-circuited to the corresponding electrode unit and then connected to the same dual-purpose signal line. In this way, an electric field generator or adapter can use fewer conductive traces to control the multiple electrode units in zones and sample the temperature detection signals, and the quality of the electrode sheet can be inspected based on the sampled temperature detection signals.

The invention provides a tumor electric field treatment system and an electrode thereof, the electrode comprises an electrode array, the electrode array comprises a substrate and a plurality of temperature sensors arranged on the substrate, the substrate is provided with a plurality of main body parts and a plurality of connecting strips connecting two adjacent main body parts, and the plurality of temperature sensors are selectively arranged on part of the main body parts. Each temperature sensor is provided with a grounding end and a signal end, the plurality of main body parts have different areas, the main body parts with the largest area and the smallest area are respectively provided with the temperature sensors, conducting strips are arranged on the front surfaces of the main body parts, AC wires for transmitting AC electric signals are arranged on the front surfaces of the connecting strips, and the AC wires are electrically connected with the corresponding conducting strips; the back surface of the substrate is provided with a grounding wire used for being connected with a grounding end and a signal wire used for being connected with a signal end. By reasonably setting the positions and the number of the temperature sensors, the wiring difficulty is reduced, the projection overlapping area of the AC line and the signal line is reduced, and mutual crosstalk of AC electric signals and temperature measurement signals is avoided.

Combination therapies for the treatment of cancers are provided. In some aspects, a nucleic acid encoding a transdifferentiation determinant is administered in combination with a chemotherapeutic, electric fields therapy (e.g., TTField), or electromagnetic fields therapy to synergistically treat a cancer such as a glioma or glioblastoma (GBM).

This invention relates to a device for electric field therapy of the human digestive tract, comprising: an inner guide rod, an outer sleeve, a rotating ring, and a supporting component, with an electrode array membrane spirally wound around the supporting component. When the supporting component is in a radially contracted state, the invention can be placed within the surgical instrument channel of a commonly used gastroscopy. When the supporting component is in a radially expanded state, it supports the electrode array membrane, enabling accurate electric field therapy of the upper digestive tract, particularly the inner wall of the duodenum.

The invention belongs to the technical field of gene application and tumor treatment, and particularly relates to a personalized tumor electric field treatment system and method based on DAPK2 gene feedback regulation. The invention provides the application of the expression of the DAPK2 gene as a marker for optimizing tumor electric field treatment parameters, and the tumor electric field treatment parameters are optimized and adjusted by utilizing the expression change condition of the DAPK2 gene. The invention further provides a tumor electric field treatment parameter optimization device. The tumor electric field treatment parameter optimization device comprises a clinical biopsy detection unit, a treatment parameter control unit, a data processing unit and the like. Through a dynamic feedback regulation mechanism, optimization of personalized tumor electric field treatment is realized, the treatment effect is ensured to be maximized, side effects are reduced, and the life quality of a patient is improved.

The present invention relates to the field of medical instrument technology, and specifically to a control device and electronic device for electrical stimulation and electric field therapy equipment, wherein the electrical stimulation and electric field therapy equipment includes a feedback unit and an AC / DC unit, and the device is used to perform the following method: obtaining the setting results of the current control parameters of the electrical stimulation and electric field therapy equipment, wherein the current control parameters include the current operating mode and configuration parameters, wherein the current operating mode includes a first mode for electrical stimulation or a second mode for electric field therapy; obtaining the electrical signal fed back by the feedback unit; and adjusting the reference voltage or drive signal of the AC / DC unit based on the current operating mode, the configuration parameters, and the electrical signal. This method adopts different control strategies for different operating modes, ensuring high-precision current control, thereby realizing high-current control precision head and muscle electrical stimulation and electric field therapy applications, and expanding the application range of the control.

The application provides an implantable electrode and an electric field treatment device for intracranial tumor treatment. The implantable electrode for intracranial tumor treatment comprises a flexible electrode, the flexible electrode comprises a flexible base layer and at least one electrode unit arranged on the flexible base layer, at least one end of the flexible base layer is not covered by the electrode unit, and an extension section is formed at the part of the flexible base layer not covered by the electrode unit. The electric field treatment device comprises a control module and the implantable electrode, the control module and the flexible electrode of the implantable electrode are electrically connected to generate an alternating electric field. The flexible electrode can be attached to the surface of a tumor cavity by surface adhesion, and the extension section can extend out of the tumor cavity and be attached to the surface of brain tissue, so that the flexible electrode can be stably fixed in the body. Therefore, the targeting of tumor electric field treatment can be obviously improved, the stability of the electric field in the related area can be improved, the compliance of the patient can be improved, adverse reactions can be reduced, and the treatment effect can be improved as a whole.

The present application provides a tumor electric field therapy system, including an electric field generator and a plurality of electrode patches arranged in pairs, wherein the plurality of pairs of electrode patches include a pair of first electrode patches and a pair of second electrode patches, wherein the first electrode patches and the second electrode patches are each provided with a plurality of electrode units, wherein the plurality of electrode units in the same row of the first electrode patch have centers on the same arc line, and the plurality of electrode units in the same row of the second electrode patch have centers on the same horizontal line. The tumor electric field therapy system of the present application includes a first electrode patch and a second electrode patch, wherein the electrode units of the first electrode patch and the second electrode patch are distributed in different ways, wherein the current density mean of the first electrode patch is relatively low, and the current density uniformity of the second electrode patch is better, and corresponding electrode patches can be applied to different areas of the patient.

The invention provides a tumor electric field treatment system which comprises an electrode plate and a controller, the electrode plate comprises a plurality of electrode units and a handshake chip, and each electrode unit comprises a dielectric element and a temperature sensor with a signal end and a grounding end. The plurality of electrode units are arranged in at least two rows and two columns on the circuit, the grounding ends of the temperature sensors in the same row are in short circuit through the same path of grounding wire, and the signal ends of the temperature sensors in the same column group are in short circuit through the same path of dual-purpose signal wire. The dual-purpose signal line is configured to transmit an alternating current signal to the corresponding dielectric element in a first mode, and transmit a direct current signal or a temperature signal detected by the corresponding temperature sensor to the signal end of the corresponding temperature sensor in a second mode. The controller is configured to communicate with the handshake chip so as to judge the connection state of the electrode slices, and is configured to combine and control the states of the grounding wire and the dual-purpose signal line when the electrode slices are normally connected so as to enable the dual-purpose signal line to be switched between transmission of an alternating current electric signal and transmission of a temperature detection signal.

The invention is suitable for the technical field of pulsed electric field treatment and computer simulation, and provides a COMSOL-based tumor ablation preoperative needle arrangement scheme generation system and device. In the embodiment of the invention, a three-dimensional simulation geometric model of a target tissue is constructed through COMSOL multi-physics field simulation software, and then an initial needle arrangement scheme is determined through the three-dimensional simulation geometric model. The method comprises the following steps: establishing a three-dimensional simulation geometric model, determining material parameters and boundary conditions of the three-dimensional simulation geometric model, constructing a multi-physical field tumor ablation simulation model, determining electric field energy distribution data during an ablation operation according to an initial needle arrangement scheme through the simulation model, and comparing the data with a target region to determine a target needle arrangement scheme. According to the method, the electric field and the thermal field are combined in construction of the multi-physics field tumor ablation simulation model, and the corresponding conductivity is set when the model material parameters are set, so that the problems of lack of multi-physics field coupling analysis and insufficient dynamic parameter optimization in the prior art are solved, and the accuracy of a needle arrangement scheme is improved.