Multi-channel sampling centrifugal tube

The multi-channel sampling centrifuge tubes split the liquid into a split tube via the main inlet tube and are equipped with a sealing component, which solves the problem of inconvenient operation of existing centrifuge tubes and achieves efficient sample dispensing and storage, making them suitable for clinical diagnosis and molecular biology research.

CN223543018UActive Publication Date: 2025-11-14TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH
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Patent Information

Application Number
CN202423093838.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-16
Publication Date
2025-11-14
Estimated Expiration
2034-12-16

AI Technical Summary

Technical Problem

Existing centrifuge tubes need to be dispensed into different centrifuge tubes during the sampling process, which cannot achieve simultaneous multi-tube sampling and retention, making the operation inconvenient and inefficient.

Method used

A multi-channel sampling centrifuge tube was designed, which automatically diverts the sample liquid into multiple diversion tubes through the main inlet tube. A sealing rubber column and a sealing component are set at the outlet end of the diversion tube to realize the diversion and sealing of the sample liquid. After the sample liquid enters the centrifuge tube, it can be directly centrifuged and stored.

Benefits of technology

It achieves simultaneous multi-tube sampling and retention, improving the efficiency of sample aliquoting, storage, and centrifugation, and is particularly suitable for clinical diagnosis and molecular biology research.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a multichannel sampling centrifuge tube, which comprises a liquid inlet main tube and a plurality of shunt tubes, the upper liquid inlet ends of the plurality of shunt tubes are communicated with the lower end of the liquid inlet main tube, and the liquid outlet ends of the plurality of shunt tubes are provided with centrifuge tubes; an upper threaded cover is arranged at the liquid outlet end of the flow dividing pipe, a sealing rubber column is fixed to the top face of the upper threaded cover, and a columnar hollow structure is formed in the sealing rubber column; a lower threaded cover is screwed and sealed at the upper end of the centrifugal tube, a movable cylinder is fixed on the top surface of the lower threaded cover, a plugging assembly is arranged in the movable cylinder, and an annular sealing plug is fixed on the inner peripheral wall of an upper threaded cover; and an upper liquid outlet hole and a lower liquid outlet hole are respectively formed in the upper threaded cover and the lower threaded cover. According to the multichannel sampling centrifugal tube, samples can be automatically shunted into branch tubes (sampling / centrifugal tubes) connected with each channel after entering the same main tube, a plurality of samples are separated by taking the branch tubes as units and are stored, and the multichannel sampling centrifugal tube can be directly used for centrifugation when being used.
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Description

Technical Field

[0001] This utility model relates to the field of sampling centrifuge tube technology, specifically to multi-channel sampling centrifuge tubes. Background Technology

[0002] Centrifuge tubes are tubular sample containers that can be sealed with a cap or a pressure cap. There are two common types of cap closures on the market: pressure cap centrifuge tubes, which are sealed by pressing and are commonly found in miniature centrifuge tubes; and screw cap centrifuge tubes, which can be further divided into flat caps (the top of the cap is flat) and stopper caps (the top of the cap has a stopper shape).

[0003] Existing centrifuge tubes require users to separate samples into different centrifuge tubes during the sampling process. The entire sample separation process cannot achieve simultaneous multi-tube sampling and retention, which is inconvenient and inefficient. Therefore, this application proposes a multi-channel sampling centrifuge tube to solve the above problems. Utility Model Content

[0004] To address the shortcomings of existing technologies, this invention provides a multi-channel sampling centrifuge tube. This multi-channel sampling centrifuge tube can automatically divert samples into branch tubes (sampling / centrifuge tubes) connected to each channel after the samples enter the same main tube. Multiple samples are separated by branch tubes and stored. When needed, they can be directly used for centrifugation.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a multi-channel sampling centrifuge tube, including a main inlet tube and multiple branch tubes, wherein the upper inlet ends of the multiple branch tubes are connected to the lower end of the main inlet tube, so as to uniformly distribute the sample liquid in the main inlet tube into the multiple branch tubes; the outlet ends of the multiple branch tubes are provided with centrifuge tubes for storing and collecting the sample liquid; the outlet end of each branch tube is provided with a downward-facing upper threaded cap, and a sealing rubber column inserted into the branch tube to seal its outlet end is fixed on the top surface of the upper threaded cap. The sealed rubber column has a columnar hollow structure inside; the upper end of the centrifuge tube is screwed with a lower threaded cap, and the top surface of the lower threaded cap is fixed with a movable cylinder that can be screwed with the upper threaded cap. The movable cylinder is equipped with a sealing component that can seal the columnar hollow structure when it moves upward. The inner circumferential wall of the upper threaded cap and near the bottom surface is fixed with an annular sealing plug that can slide and rotate to seal against the outer wall of the movable cylinder. The upper threaded cap and the lower threaded cap are respectively provided with an upper outlet hole and a lower outlet hole to allow the sample liquid in the liquid inlet tube to fall into the centrifuge tube.

[0006] Furthermore, the plurality of the diversion pipes are distributed equidistantly in a circle with the central axis of the main liquid inlet pipe as the center, and the diameter of the main liquid inlet pipe is larger than the diameter of the diversion pipes.

[0007] Furthermore, a lower sealing ring is fixed to the inner top wall of the lower threaded cover, and a lower threaded groove is opened on the outer peripheral wall of the centrifuge tube to be threadedly connected to the inner wall of the lower threaded cover.

[0008] Furthermore, an upper sealing ring is fixed to the inner top wall of the upper threaded cover, and the inner wall of the upper threaded cover is threaded on its inner wall and near the inner top wall. An upper threaded groove is opened on the outer peripheral wall of the movable cylinder near the top surface, which can be threadedly connected to the inner wall thread of the upper threaded cover.

[0009] Furthermore, the lower liquid outlet, upper liquid outlet pipe, diversion pipe, centrifuge pipe, and columnar hollow structure are all located on the same central axis. The diameter of the lower liquid outlet is smaller than the inner diameter of the centrifuge pipe and larger than the inner diameter of the lower sealing ring.

[0010] Furthermore, the lower opening of the columnar hollow structure is adapted to the upper liquid outlet hole.

[0011] Furthermore, the sealing assembly includes multiple pillars fixed to the inner peripheral wall of the movable cylinder and inclined upwards. The top of the multiple pillars is fixed with a horizontally arranged support plate, and the top surface of the support plate is fixed with a sealing column that can be inserted into the sealing rubber column.

[0012] Furthermore, the number of the support pillars is three, and they are equidistantly distributed in a circle with the central axis of the diversion pipe as the center. The top of the sealing pillar is a cone or a frustum. The columnar hollow structure is located on the same central axis as the sealing pillar, and the diameter of the columnar hollow structure is smaller than the diameter of the sealing pillar.

[0013] Compared with the prior art, the technical solution of this application has the following beneficial effects:

[0014] This multi-channel sampling centrifuge tube allows sample liquid to enter through the main inlet pipe and then be diverted into different diversion tubes before flowing back into the centrifuge tube, achieving simultaneous multi-tube sampling. After sampling, the diversion tubes can be sealed using a sealing mechanism to stop sampling. Then, the sealing rubber column is removed, separating the centrifuge tube from the diversion tube. The centrifuge tube, along with the collected sample liquid, can be stored, enabling simultaneous multi-tube sample retention. Furthermore, when the sample liquid in the centrifuge tube needs to be centrifuged, the centrifuge tube containing the retained sample liquid can be directly centrifuged, which is very convenient. The entire device is particularly suitable for experimental scenarios where multiple samples need to be aliquoted and processed simultaneously during liquid sampling, such as in clinical diagnosis, molecular biology, or biochemistry research. It effectively improves the efficiency of sample aliquoting and storage, as well as the convenience of centrifugation during use. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of this utility model;

[0016] Figure 2This is a schematic diagram of the connection structure between the diversion tube and the centrifuge tube of this utility model;

[0017] Figure 3 This utility model Figure 2 Enlarged structural diagram at point A in the middle;

[0018] Figure 4 This is a schematic diagram of the sealing mechanism of this utility model after sealing.

[0019] In the diagram: 1. Main inlet pipe; 2. Diverter pipe; 3. Centrifuge tube; 4. Upper threaded cap; 5. Lower threaded cap; 6. Movable cylinder; 7. Sealing rubber column; 8. Upper outlet hole; 9. Upper sealing ring; 10. Plug; 11. Lower sealing ring; 12. Support plate; 13. Support column; 14. Lower inlet hole; 15. Lower threaded groove; 16. Upper threaded groove; 17. Annular sealing plug. Detailed Implementation

[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0021] Please see Figure 1-4 The multi-channel sampling centrifuge tube in this embodiment includes a main inlet pipe 1 and multiple branch pipes 2. The upper inlet ends of the multiple branch pipes 2 are all connected to the lower end of the main inlet pipe 1. The multiple branch pipes 2 are distributed equidistantly in a circle with the central axis of the main inlet pipe 1 as the center. The diameter of the main inlet pipe 1 is larger than the diameter of the branch pipes 2. The multiple branch pipes 2 are integrally formed with the main inlet pipe 1. When the sample liquid enters the main inlet pipe 1, it can be evenly distributed into the multiple branch pipes 2 to achieve the effect of diversion.

[0022] Multiple shunt tubes 2 have centrifuge tubes 3 at their outlet ends for storing sample liquid. The sample liquid flows out from the lower end of the shunt tube 2 and enters the centrifuge tube 3. Specifically, the outlet end of the shunt tube 2 is provided with an upper threaded cap 4 with the opening facing downward. A sealing rubber column 7 is fixed to the top surface of the upper threaded cap 4 and inserted into the shunt tube 2 to seal its outlet end. The sealing rubber column 7 has a columnar hollow structure inside. It should be understood that when the sample liquid enters the shunt tube 2, it can flow out through the columnar hollow structure inside the sealing rubber column 7. The user can pull the sealing rubber column 7 out of the shunt tube 2 by pulling the upper threaded cap 4 downward. In addition, when the sealing rubber column 7 is inserted into the shunt tube 2, it can be in close contact with the inner wall of the shunt tube 2, that is, the sample liquid cannot flow out from the gap between the sealing rubber column 7 and the inner wall of the shunt tube 2.

[0023] Meanwhile, the upper end of the centrifuge tube 3 is screwed with a lower threaded cap 5. The top surface of the lower threaded cap 5 is fixed with a movable cylinder 6 that can be screwed with the upper threaded cap 4. The movable cylinder 6 is equipped with a sealing component that can seal the columnar hollow structure when it moves upward. The inner circumferential wall of the upper threaded cap 4 and near the bottom surface is fixed with an annular sealing plug 17 that can slide and rotate with the outer wall of the movable cylinder 6 to seal. The upper threaded cap 4 and the lower threaded cap 5 are respectively provided with an upper outlet hole 8 and a lower outlet hole to allow the sample liquid in the liquid inlet tube 1 to fall into the centrifuge tube 3.

[0024] The lower threaded cover 5 has a lower sealing ring 11 fixed on its inner top wall. The outer peripheral wall of the centrifuge tube 3 has a lower threaded groove 15 that is threaded to the inner wall of the lower threaded cover 5. The upper threaded cover 4 has an upper sealing ring 9 fixed on its inner top wall. The inner wall of the upper threaded cover 4 is threaded on its inner wall and close to the inner top wall. The outer peripheral wall of the movable cylinder 6 is open with an upper threaded groove 16 that can be threaded to the inner wall of the upper threaded cover 4. The lower liquid outlet, upper liquid outlet pipe, diversion pipe 2, centrifuge tube 3 and columnar hollow structure are all located on the same central axis. The diameter of the lower liquid outlet is smaller than the inner diameter of the centrifuge tube 3 and larger than the inner diameter of the lower sealing ring 11. The lower opening of the columnar hollow structure is adapted to the upper liquid outlet 8.

[0025] When the lower threaded cap 5 is aligned with the centrifuge tube 3, the lower threaded cap 5 can be rotated. The lower threaded cap 5 is threadedly connected to the lower threaded groove 15. With the cooperation of the lower sealing ring 11, the lower threaded cap 5 can seal the upper end of the centrifuge tube 3. Before the sealing assembly seals the columnar hollow structure inside the sealing rubber column 7, the sample liquid can flow into the upper threaded cap 4 and the movable cylinder 6 through the upper outlet hole 8. Under the action of the annular sealing plug 17, the sample liquid will not flow out from the gap between the upper threaded cap 4 and the movable cylinder 6, and thus flow into the centrifuge tube 3 through the lower outlet hole.

[0026] It should be noted that the annular sealing plug 17 can keep the movable cylinder 6 and the inner wall of the upper threaded cover 4 sealed, but does not affect the sliding of the movable cylinder 6 in the upper threaded cover 4. During the sliding of the movable cylinder 6 in the upper threaded cover 4, the two can still be sealed due to the annular sealing plug 17. At the same time, when the movable cylinder 6 slides to the point where the upper threaded groove 16 corresponds to the thread on the inner wall of the upper threaded cover 4, the movable cylinder 6 can be rotated, thereby causing the movable cylinder 6 to screw into the upper threaded cover 4. When the movable cylinder 6 tightly presses the upper sealing ring 9, the movable cylinder 6 and the upper threaded cover 4 achieve a screw seal.

[0027] The sealing assembly includes multiple support columns 13 fixed to the inner circumferential wall of the movable cylinder 6 and inclined upwards. The top of the multiple support columns 13 is fixed with a horizontally arranged support plate 12. The top surface of the support plate 12 is fixed with a sealing column 10 that can be inserted into the sealing rubber column 7. There are three support columns 13, which are equidistantly distributed in a circle with the central axis of the diversion pipe 2 as the center. The top of the sealing column 10 is a cone or frustum. The columnar hollow structure is located on the same central axis as the sealing column 10, and the diameter of the columnar hollow structure is smaller than the diameter of the sealing column 10.

[0028] After the sample liquid in centrifuge tube 3 has been collected, centrifuge tube 3 can be slid upward, causing the movable cylinder 6 to slide into the upper threaded cap 4. During this process, the top of the sealing column 10 is first inserted into the cylindrical hollow structure inside the sealing rubber column 7. When the movable cylinder 6 slides to the point where the upper threaded groove 16 corresponds to the inner thread of the upper threaded cap 4, the movable cylinder 6 can be rotated to achieve a screw seal between the movable cylinder 6 and the upper threaded cap 4. At this time, the sealing column 10 is inserted into the cylindrical hollow structure inside the sealing rubber column 7, thereby preventing the sample liquid in the split tube 2 from flowing out of the cylindrical hollow structure, thus sealing the split tube 2. Since the sample liquid in centrifuge tube 3 has been collected, the upper threaded cap 4 can be pulled downward, thereby causing the sealing rubber column 7 to detach from the split tube, separating centrifuge tube 3 from the split tube 2. Centrifuge tube 3 can be stored with the collected sample liquid, thus achieving sample retention of the sample liquid collected in centrifuge tube 3. In addition, when the sample liquid in centrifuge tube 3 needs to be centrifuged, centrifuge tube 3 with the retained sample liquid can be directly centrifuged.

[0029] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0030] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A multi-channel sampling centrifuge tube, characterized in that, include: The liquid inlet main pipe (1) and multiple diversion tubes (2) are provided. The upper liquid inlet end of the multiple diversion tubes (2) is connected to the lower end of the liquid inlet main pipe (1) so that the sample liquid in the liquid inlet main pipe (1) is evenly diverted into the multiple diversion tubes (2). The liquid outlet end of the multiple diversion tubes (2) is provided with a centrifuge tube (3) for storing and taking sample liquid. The outlet end of the diversion pipe (2) is provided with an upper threaded cap (4) with the opening facing downward. A sealing rubber column (7) is fixed on the top surface of the upper threaded cap (4) and inserted into the diversion pipe (2) to seal its outlet end. The sealing rubber column (7) has a columnar hollow structure inside. The upper end of the centrifuge tube (3) is screwed with a lower threaded cap (5). The top surface of the lower threaded cap (5) is fixed with a movable cylinder (6) that can be screwed with the upper threaded cap (4). The movable cylinder (6) is provided with a sealing component that can seal the columnar hollow structure when it moves upward. The inner circumferential wall of the upper threaded cap (4) and near the bottom surface is fixed with an annular sealing plug (17) that can slide and rotate to seal with the outer wall of the movable cylinder (6). The upper threaded cap (4) and the lower threaded cap (5) are respectively provided with an upper outlet hole (8) and a lower outlet hole, which allow the sample liquid in the liquid inlet pipe (1) to fall into the centrifuge tube (3).

2. The multi-channel sampling centrifuge tube according to claim 1, characterized in that: Multiple diverter pipes (2) are distributed equidistantly around the central axis of the main inlet pipe (1), and the diameter of the main inlet pipe (1) is larger than the diameter of the diverter pipes (2).

3. The multi-channel sampling centrifuge tube according to claim 1, characterized in that: The inner top wall of the lower threaded cover (5) is fixed with a lower sealing ring (11), and the outer peripheral wall of the centrifuge tube (3) is provided with a lower threaded groove (15) that is threadedly connected to the inner wall of the lower threaded cover (5).

4. The multi-channel sampling centrifuge tube according to claim 1, characterized in that: The upper sealing ring (9) is fixed on the inner top wall of the upper threaded cover (4). The inner wall thread of the upper threaded cover (4) is located on its inner wall and near the inner top wall. The outer peripheral wall of the movable cylinder (6) near the top surface is provided with an upper threaded groove (16) that can be threadedly connected to the inner wall thread of the upper threaded cover (4).

5. The multi-channel sampling centrifuge tube according to claim 1, characterized in that: The lower liquid outlet, upper liquid outlet pipe, diversion pipe (2), centrifuge pipe (3) and columnar hollow structure are all located on the same central axis. The diameter of the lower liquid outlet is smaller than the inner diameter of the centrifuge pipe (3) and larger than the inner diameter of the lower sealing ring (11).

6. The multi-channel sampling centrifuge tube according to claim 5, characterized in that: The lower opening of the columnar hollow structure is adapted to the upper liquid outlet (8).

7. The multi-channel sampling centrifuge tube according to claim 6, characterized in that: The sealing assembly includes multiple support columns (13) fixed to the inner peripheral wall of the movable cylinder (6) and inclined upwards. The top of the multiple support columns (13) is fixed with a horizontally arranged support plate (12). The top surface of the support plate (12) is fixed with a sealing column (10) that can be inserted into the sealing rubber column (7).

8. The multi-channel sampling centrifuge tube according to claim 7, characterized in that: The number of the support pillars (13) is three and they are distributed equidistantly in a circle with the central axis of the diversion pipe (2) as the center. The top of the sealing pillar (10) is a cone or a frustum. The columnar hollow structure is located on the same central axis as the sealing pillar (10) and the diameter of the columnar hollow structure is smaller than the diameter of the sealing pillar (10).