Blood collection tube and sample analysis system

Abstract

The utility model discloses a blood collection tube and a sample analysis system. The blood collection tube comprises an outer tube, an inner tube and a supporting part, the outer pipe is provided with a second inner cavity with one open end; the inner tube is contained in the second inner cavity and comprises a first containing part, the first containing part comprises a first bottom and a first side part connected to the first bottom, the first bottom and the first side part jointly define a first inner cavity used for containing a sample and provided with an opening in one end, and an opening of the first inner cavity faces an opening of the second inner cavity; a gap is formed between the first side part and the outer pipe, and the outer pipe supports the inner pipe through the supporting part, so that a set distance is formed between the first bottom part and the tail end of the outer pipe; within the axial extension range of the first side part, the inner diameter of the first accommodating part is basically consistent. Compared with the inner pipe with the equal-diameter section and the variable-diameter section, customization processing does not need to be conducted on a mold and a corresponding production process, and therefore the design cost and the production cost can be reduced.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical instrument technical field especially is involved in a kind of blood collection tube and sample analysis system. BACKGROUND

[0002] The inner cavity for storing blood sample in blood collection tube needs to be kept in sealed state, in order to inject blood into the inner cavity, part of air in the inner cavity needs to be extracted to form negative pressure, the volume of extracted air is equal to the volume of blood to be injected, so under the action of certain internal and external pressure difference, blood can be injected more smoothly. The inner cavity volume of typical blood collection tube is generally between 4ml to 5ml, if the amount of injected blood is less (for example 1ml), only 1ml of air will be extracted from the inner cavity, which causes the inner cavity to still maintain relatively high pressure, and the internal and external pressure difference is small, so as to reduce the speed of blood injection. Based on the foregoing problems, there is currently a double-layer blood collection tube, which includes an outer tube and an inner tube, the inner tube is placed in the outer tube, and the total volume of the inner cavity of the inner tube is small, so as to improve the problem of slow injection caused by too large inner cavity. However, the double-layer blood collection tube in the related art has the problems of high production cost. SUMMARY

[0003] The utility model aims at at least one of the technical problems existing in the prior art. To this end, the utility model provides a blood collection tube, which can improve the problem of high cost of blood collection tube.

[0004] The utility model further provides a sample analysis system.

[0005] According to the blood collection tube in the first embodiment of the utility model, the outer tube, the inner tube and the supporting portion are included.

[0006] The outer tube has a second inner cavity with one end open.

[0007] The inner tube is accommodated in the second inner cavity, and the inner tube includes a first accommodating portion, the first accommodating portion includes a first bottom and a first side portion connected to the first bottom, the first bottom and the first side portion jointly form a first inner cavity for accommodating samples with one end open, the opening of the first inner cavity faces the opening of the second inner cavity, and the first side portion has a gap with the outer tube, and the outer tube supports the inner tube through the supporting portion, so that the first bottom and the tail end of the outer tube are spaced apart by a certain distance.

[0008] Among them, the inner diameter of the first accommodating portion is substantially consistent within the axial extension range of the first side portion.

[0009] The blood collection tube according to the embodiments of the utility model has at least the following beneficial effects:

[0010] The inner diameter of the first accommodating portion is substantially consistent in the axial extension range of the first side portion, which does not need to customize the mold and the corresponding production process compared with the inner tube with the equal-diameter section and the variable-diameter section, and thus the design cost and the production cost can be reduced.

[0011] According to the blood collection tube in the second embodiment of the present application, the outer tube has a second inner cavity with one end being open, the inner tube is accommodated in the second inner cavity, the inner tube comprises a first accommodating portion, the first accommodating portion comprises a first bottom and a first side portion connected to the first bottom, the first bottom and the first side portion jointly surround a first inner cavity for accommodating a sample and with one end being open, the opening of the first inner cavity faces the opening of the second inner cavity, the first side portion has a gap with the outer tube, and the outer tube supports the inner tube through the support portion so that the first bottom and the tail end of the outer tube are spaced apart by a certain distance.

[0012] The outer tube has a second inner cavity with one end being open.

[0013] The inner tube is accommodated in the second inner cavity, the inner tube comprises a first accommodating portion, the first accommodating portion comprises a first bottom and a first side portion connected to the first bottom, the first bottom and the first side portion jointly surround a first inner cavity for accommodating a sample and with one end being open, the opening of the first inner cavity faces the opening of the second inner cavity, the outer tube supports the inner tube through the support portion so that the first bottom and the tail end of the outer tube are spaced apart by a certain distance.

[0014] In the axial extension range of the first side portion and in the direction from the end of the second inner cavity with the opening to the tail end of the outer tube, the inner diameter of the first accommodating portion gradually decreases.

[0015] According to the blood collection tube in the third embodiment of the present application, the outer tube has a second inner cavity with one end being open, the inner tube is accommodated in the second inner cavity, the inner tube comprises a first accommodating portion, the first accommodating portion comprises a first bottom and a first side portion connected to the first bottom, the first bottom and the first side portion jointly surround a first inner cavity for accommodating a sample and with one end being open, the opening of the first inner cavity faces the opening of the second inner cavity, the outer tube supports the inner tube through the support portion so that the first bottom and the tail end of the outer tube are spaced apart by a certain distance.

[0016] The outer tube has a second inner cavity with one end being open.

[0017] The inner tube is accommodated in the second inner cavity, the inner tube comprises a first accommodating portion, the first accommodating portion comprises a first bottom and a first side portion connected to the first bottom, the first bottom and the first side portion jointly surround a first inner cavity for accommodating a sample and with one end being open, the opening of the first inner cavity faces the opening of the second inner cavity, the outer tube supports the inner tube through the support portion so that the first bottom and the tail end of the outer tube are spaced apart by a certain distance.

[0018] The gap between the first side portion and the outer tube has an air pressure smaller than the atmospheric pressure.

[0019] In other embodiments of the present application, the air pressure in the gap is smaller than the air pressure in the first inner cavity.

[0020] In other embodiments of the present application, the air pressure in the gap between the first side portion and the outer tube is smaller than the atmospheric pressure.

[0021] In other embodiments of the present application, the air pressure in the gap is less than the air pressure in the first inner cavity.

[0022] In other embodiments of the present application, the first accommodating portion is in interference fit with the outer tube at the one end of the first inner cavity having an opening.

[0023] In other embodiments of the present application, the first accommodating portion further comprises an annular flange arranged on the outer surface of the first side portion for realizing the interference fit between the first accommodating portion and the outer tube.

[0024] In other embodiments of the present application, one end of the supporting portion is connected to the first bottom of the first accommodating portion, and the other end extends to the tail end of the outer tube and abuts against the outer tube.

[0025] In other embodiments of the present application, the outer tube comprises a second accommodating portion, the second accommodating portion comprises a second bottom and a second side portion connected to the second bottom, and the second bottom and the second side portion jointly form the second inner cavity.

[0026] In other embodiments of the present application, the second bottom has an inner surface arranged towards the opening of the second inner cavity and an outer surface arranged away from the opening, the axial distance between the nearest point of the inner surface closest to the outer surface and the farthest point of the outer surface farthest from the inner surface is equal to the set distance, the second bottom is arranged as the supporting portion, and the first bottom abuts against at least the nearest point of the inner surface of the second bottom.

[0027] In other embodiments of the present application, the inner tube is made of a first material, and the outer tube is made of a second material, and the first material is different from the second material.

[0028] In other embodiments of the present application, the first material is polypropylene, and the second material is polyethylene terephthalate.

[0029] In other embodiments of the present application, the wall thickness of the first side portion is substantially uniform.

[0030] In other embodiments of the present application, the inner diameter of the first accommodating portion is greater than or equal to 6 mm and less than or equal to 7.5 mm within the axial extension range of the first side portion.

[0031] And / or, the outer diameter of the outer tube is greater than or equal to 12 mm and less than or equal to 13 mm.

[0032] In other embodiments of the present application, the ratio of the inner diameter of the first accommodating portion to the outer diameter of the outer tube is greater than or equal to 0.5 and less than or equal to 0.63 within the axial extension range of the first side portion.

[0033] In other embodiments of the present application, the set distance is greater than or equal to 10 mm.

[0034] In other embodiments of the present application, the ratio of the length of the outer tube to the length of the first accommodating portion is greater than or equal to 1.3 and less than or equal to 2.

[0035] In other embodiments of the present application, the volume of the first inner cavity is not greater than 2.5 ml.

[0036] In other embodiments of the present application, the outer tube comprises a second accommodating portion, the second accommodating portion comprises a second bottom portion and a second side portion connected to the second bottom portion, and the second bottom portion and the second side portion jointly form the second inner cavity, wherein the inner diameter of the second accommodating portion is substantially uniform within the axial extension range of the second side portion.

[0037] According to the sample analysis system in the fourth embodiment of the present application, comprising:

[0038] The sample suction needle mechanism comprises a sample suction needle and a driving mechanism, the sample suction needle is installed on the driving mechanism, and the driving mechanism is used for controlling the sample suction needle to suck the sample from the blood collection tube in any one of the preceding embodiments;

[0039] The sensing mechanism is used for detecting the position of the interface between the plasma and the blood cells in the blood collection tube;

[0040] The controller is used for controlling the needle lowering height and the sample suction speed of the sample suction needle according to the detection signal of the sensing mechanism;

[0041] The reagent needle mechanism is used for sucking the reagent from the reagent carrying mechanism and mixing the sucked reagent with the sample sucked by the sample suction needle mechanism for reaction;

[0042] The detection mechanism is used for detecting the mixed solution of the reagent and the sample.

[0043] In other embodiments of the present application, the detection mechanism is a blood coagulation analyzer.

[0044] Additional aspects and advantages of the present application will be given in part in the following description, will become apparent from the following description, or will be learned by practice of the present application. BRIEF DESCRIPTION OF DRAWINGS

[0045] The present application will be further described below in combination with the drawings and embodiments, wherein:

[0046] Figure 1 is a cross-sectional view of the blood collection tube in another embodiment of the present application;

[0047] Figure 2 is a cross-sectional view of the blood collection tube in another embodiment of the present application;

[0048] Figure 3 is a cross-sectional view of the blood collection tube in another embodiment of the present application.

[0049] Reference signs:

[0050] Blood collection tube 10, gap 11;

[0051] Inner tube 100, first inner cavity 101, first accommodating portion 110, first bottom 111, first side portion 112, annular flange 113;

[0052] Outer tube 200, second inner cavity 201, second accommodating portion 210, second bottom 211, inner surface 211a, outer surface 211b, second side portion 212;

[0053] Support portion 300;

[0054] Rubber plug 400;

[0055] Tube cover 500. DETAILED DESCRIPTION

[0056] The embodiments of the present application will be described in detail below, examples of which are shown in the drawings, wherein the same or similar notations represent the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by reference to the drawings are exemplary only, and are for the purpose of explanation of the present application, and are not to be understood as a limitation of the present application.

[0057] In the description of the present application, it is to be understood that, if the orientation description, such as the upper, lower, front, rear, left, right and the like, the orientation or position relationship is based on the orientation or position relationship shown in the drawings, and is only for the convenience of describing the present application and simplifying the description, and therefore cannot be understood as a limitation of the present application.

[0058] In the description of the present application, the meaning of several is more than one, the meaning of multiple is more than two, greater than, less than, more than and the like are not included in the number, above, below, within and the like are included in the number. If there is a description of the first, second, only for the purpose of distinguishing the technical features, and cannot be understood as indicating or implying the relative importance or implicitly indicating the number of indicated technical features or implicitly indicating the sequence of indicated technical features.

[0059] In the description of the utility model, unless otherwise expressly limited, the words such as setting, installation, connection should be understood broadly, and the skilled in the art can determine the specific meaning of the above words in the utility model in combination with the specific content of technical scheme.

[0060] In the description of the utility model, the description of reference terms "one embodiment", "some embodiments", "illustrative embodiment", "example", "specific example" or "some examples" means that the specific features, structures, materials or characteristics described in combination with the embodiment or example are contained in at least one embodiment or example of the utility model. In the specification, the illustrative description of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0061] As described previously, the double-layer blood collection tube in the related art has problems of high production cost, and specifically, the inner tube of the double-layer blood collection tube is usually divided into multiple sections, such as an equal-diameter section with a constant inner diameter and a variable-diameter section with a variable inner diameter. Since the inner tube has these different sections, it needs to customize the mold and the corresponding production process, thereby increasing the design cost and the production cost. Based on this, the utility model provides a blood collection tube, which can reduce the production cost, and the following will be described in combination with the drawings and specific embodiments.

[0062] Referring to Figure 1 , a cross-sectional view of the first embodiment of the utility model is shown, as shown in the figure, the blood collection tube 10 includes an inner tube 100 and an outer tube 200, wherein the outer tube 200 can be a conventional constant tube, which can be placed on a sample rack for transfer. The inner tube 100 is a micro tube, which can be accommodated in the outer tube 200, and the micro tube can also be loaded through the sample rack by taking the outer tube 200 as a carrier. It should be noted that the shape of the inner tube 100 can be adaptively designed according to the shape of the outer tube 200, so as to realize stable placement of the inner tube 100 without changing the outer tube 200. It should be noted that the blood collection tube 10 involved in the utility model can be used for storing conventional peripheral blood, and can be suitable for storing venous blood. In cooperation with the micro detection function of the coagulation analyzer, coagulation analysis can be realized through a small amount of blood sample, which can reduce the consumption of samples compared with the conventional coagulation analyzer.

[0063] As Figure 1As shown, the outer tube 200 has a second inner cavity 201 which is open at one end, the second inner cavity 201 can be used to contain a sample (e.g. a blood sample) when the outer tube 200 is used as a constant tube, and can be used to contain the inner tube 100 when used as a carrier of the inner tube 100, for the sake of description, the opening of the outer tube 200 is named as a second opening, and the end of the outer tube 200 having the opening is defined as a head end, and the end opposite to the head end is defined as a tail end. Specifically to Figure 1 In the embodiment shown, the outer tube 200 is approximately cylindrical in shape, and when the outer tube 200 is placed in a normal vertical posture, the second opening is arranged upward.

[0064] The inner tube 100 has a first inner cavity 101 which is open at one end, the first inner cavity 101 is used to contain a sample (e.g. a blood sample), for the sake of description, the opening of the inner tube 100 is named as a first opening, and the end of the inner tube 100 having the opening is also defined as a head end, and the end opposite to the head end is defined as a tail end, when the inner tube 100 is placed in a normal working posture in the outer tube 200, the first opening is arranged toward the second opening. Specifically to Figure 1 In the embodiment shown, the inner tube 100 is approximately cylindrical in shape, and when the inner tube 100 is placed in a normal vertical posture in the outer tube 200, the first opening is arranged upward. The air pressure in the first inner cavity 101 is lower than the atmospheric pressure, so as to adapt to the collection of venous blood.

[0065] In this embodiment, the inner tube 100 includes a first containing portion 110, the first containing portion 110 includes a first bottom 111 and a first side 112, the first side 112 is connected to the first bottom 111, and the two together define the aforementioned first inner cavity 101 which is open at one end. It should be noted that the first bottom 111 should be understood according to the usual meaning, that is, located at the tail end (or bottom end) of the inner tube 100 and constitutes the bottom of the first inner cavity 101, in order to further assist understanding, in Figure 1 The range of the first bottom 111 and the first side 112 is approximately identified by a dashed line in the figure, for example, the first bottom 111 is an arc-shaped bottom which is convex downward, the first side 112 is a cylindrical barrel structure, and the lower end of the first side 112 is connected to the upper end of the first bottom 111; for example, the second side 212 is tangent to the upper end of the first bottom 111, and the position where the two are tangent can be regarded as the boundary between the two.

[0066] In the embodiment, as described above, the first side portion 112 presents a cylindrical barrel structure, that is, the inner diameter of the first accommodating portion 110 is substantially uniform in the axial extension range of the first side portion 112, and it is to be noted that the “substantially uniform” herein includes the case of complete uniformity or negligible inner diameter variation under normal detection conditions, and the “negligible inner diameter variation” hereinafter is generally caused by production errors, draft angles, etc. Since the first side portion 112 cooperates with the first bottom portion 111 to define the first inner cavity 101, that is, the first side portion 112 extends to the first opening, it can be considered that the inner diameter of the part of the first accommodating portion 110 other than the first bottom portion 111 is substantially uniform, and compared with the inner tube having an equal diameter section and a variable diameter section, it does not need to customize the mold and the corresponding production process, thereby reducing the design and production costs.

[0067] On the basis of the first embodiment, in some embodiments, with reference to Figure 1 , Figure 2 , the blood collection tube 10 further comprises a support portion 300, and the outer tube 200 supports the inner tube 100 through the support portion 300, so that the first bottom portion 111 and the tail end of the outer tube 200 are spaced apart by a set distance. As described above, the outer tube 200 is a constant tube, the volume of the second inner cavity 201 is large, and the length is also relatively long. By supporting the inner tube 100 through the support portion 300, the first bottom portion 111 and the tail end of the outer tube 200 are spaced apart by a set distance H. In this way, the length of the inner tube 100 can be reduced without changing the length of the outer tube 200, thereby reducing the volume of the first inner cavity 101 of the inner tube 100. The set distance should be such that the volume of the first inner cavity 101 is suitable for injecting a small amount of blood. For example, by setting the support portion 300 to shorten the length of the inner tube 100, the volume of the first inner cavity 101 is 2ml. When 1ml is drawn from the first inner cavity 101 (so as to accommodate 1ml of blood), the air pressure of the first inner cavity 101 will decrease significantly, thereby facilitating smooth injection of blood. It is to be noted that the “distance between the first bottom portion 111 and the tail end of the outer tube 200” herein specifically refers to the distance between the farthest point of the first bottom portion 111 away from the first opening and the farthest point of the tail end of the outer tube 200. For example, when the first bottom portion 111 is an arc-shaped bottom portion protruding downward as shown in Figure 1 , the farthest point is specifically the lowest point. Similarly, when the tail end of the outer tube 200 is an arc-shaped tail end protruding downward as shown in Figure 1 , the farthest point is specifically the lowest point. For the purpose of auxiliary understanding, Figure 1 , the set distance H is also roughly identified by a dashed line.

[0068] When the blood collection tube 10 further comprises the support portion 300, in some embodiments, with reference to Figure 1The support portion 300 is a part of the inner tube 100, one end of which is connected to the first bottom portion 111 of the first accommodating portion 110, and the other end of which extends to the tail end of the outer tube 200 and abuts against the outer tube 200. Exemplarily, the support portion 300 is a hollow tubular structure, the outer diameter of which is equal to or smaller than the outer diameter of the first accommodating portion 110, and the tail end of the support portion 300 abuts against the bottom portion of the outer tube 200. Exemplarily, the support portion 300 can also be a solid columnar structure, the center of which is connected to the first bottom portion 111. Exemplarily, the support portion 300 can also include a plurality of sub-support portions which are spaced apart along the circumference of the first accommodating portion 110.

[0069] When the blood collection tube 10 further includes the support portion 300, in some other embodiments, with reference to Figure 2 , the support portion 300 is a part of the outer tube 200. Specifically, the outer tube 200 includes a second accommodating portion 210, which includes a second bottom portion 211 and a second side portion 212, the second side portion 212 being connected to the second bottom portion 211, and the two together surround the aforementioned second inner cavity 201. It should be noted that the second bottom portion 211 should be understood according to the usual meaning, that is, located at the tail end (or referred to as the bottom end) of the outer tube 200 and constitutes the bottom of the second inner cavity 201. In order to further assist understanding, the range of the second bottom portion 211 and the second side portion 212 is roughly indicated by a dashed line in Figure 2 . Exemplarily, the second bottom portion 211 presents as an arc-shaped bottom portion which protrudes downward, and the second side portion 212 presents as a cylindrical barrel structure, and the lower end of the second side portion 212 is connected to the upper end of the second bottom portion 211; Exemplarily, the second side portion 212 is tangent to the upper end of the second bottom portion 211, and the tangent position of the two can be regarded as the boundary between the two.

[0070] In this embodiment, the second bottom portion 211 is provided as the support portion 300, that is, the support portion 300 and the second bottom portion 211 are the same structure, and the second bottom portion 211 has an inner surface 211a provided towards the opening of the second inner cavity 201 and an outer surface 211b provided away from the opening. Exemplarily, the inner surface 211a is the upper surface in Figure 2 , and the outer surface 211b is the lower surface in Figure 2 . The axial distance between the nearest point of the inner surface 211a closest to the outer surface 211b and the farthest point of the outer surface 211b farthest from the inner surface 211a is equal to the aforementioned set distance H. In other words, this embodiment is the same as Figure 1Compared to the illustrated embodiment, the bottom of the outer tube 200 is thickened, and the thickened portion supports the inner tube 100. For example, when the blood collection tube 10 is placed vertically, the closest point of the inner surface 211a to the outer surface 211b is the lowest point of the inner surface 211a, and the farthest point of the outer surface 211b from the inner surface 211a is the lowest point of the outer surface 211b. Furthermore, the first bottom 111 at least abuts against the closest point of the inner surface 211a of the second bottom 211, thus ensuring that the first bottom 111 is spaced from the tail end of the outer tube 200 by the aforementioned predetermined distance H.

[0071] It should be noted that the farthest point on the outer surface 211b from the inner surface 211a is not limited to the center point of the outer surface 211b, nor is it limited to a single point. Figure 2 For example, the outer surface 211b of the second bottom 211 is provided with a non-through groove. At this time, each point on the edge of the groove can be used as the farthest point of the outer surface 211b that is farthest from the inner surface 211a.

[0072] In other embodiments, the support portion 300 may also be a component independent of the inner tube 100 and the outer tube 200.

[0073] Based on the first embodiment, in some embodiments, reference is made to Figure 1 There is a gap 11 between the first side portion 112 and the outer tube 200. The presence of this gap 11 can reduce the outer diameter of the inner tube 100, and correspondingly reduce the inner diameter of the inner tube 100, thereby reducing the volume of the first inner cavity 101. Similarly, the size of the gap 11 should be such that the volume of the first inner cavity 101 is suitable for the injection of a small amount of blood, while also ensuring that the first inner cavity 101 is not too small to be suitable for inserting an injection needle, and reducing the probability of the injection needle touching the inner wall.

[0074] When there is a gap 11 between the first side portion 112 and the outer tube 200, in some embodiments, the air pressure in the gap 11 is less than atmospheric pressure. In this way, the leakage of gas in the gap 11 into the first inner cavity 101 can be reduced or eliminated, thereby giving the blood collection tube 10 a longer shelf life. Specifically, when the air pressure in the gap 11 is less than atmospheric pressure and less than or equal to the air pressure in the first inner cavity 101, the gas in the gap 11 will not leak into the first inner cavity 101. When the air pressure in the gap 11 is less than atmospheric pressure and greater than the air pressure in the first inner cavity 101, even if the gas in the gap 11 leaks into the first inner cavity 101 due to the pressure difference, the pressure difference can be reduced compared to the case where the air pressure in the gap 11 is equal to atmospheric pressure, thereby reducing the leakage.

[0075] Based on the first embodiment, in some embodiments, reference is made to Figure 1The blood collection tube 10 further comprises a rubber plug 400, which is elastic and easily punctured by the injection needle. At least a portion of the rubber plug 400 is inserted into the outer tube 200, thereby directly closing the second opening, so that the second inner cavity 201 is in a sealed state. In some embodiments, the portion of the rubber plug 400 in the outer tube 200 also abuts against the leading end of the inner tube 100, thereby directly closing the first opening, so that the first inner cavity 101 is in a sealed state. In other embodiments, the portion of the rubber plug 400 in the outer tube 200 does not directly abut against the leading end of the inner tube 100, but forms a sealing relationship between the leading end of the inner tube 100 and the inner wall of the outer tube 200, so that the first inner cavity 101 is also in a sealed state.

[0076] In some embodiments, an unpenetrated groove is formed on the end of the rubber plug 400 away from the outer tube 200 (e.g., the upper end in the drawings). The groove can reduce the thickness of the portion of the rubber plug 400 in the axial direction of the outer tube 200, thereby reducing the resistance when the injection needle passes through the rubber plug 400. Since the groove is unpenetrated, the sealing effect can be ensured.

[0077] In some embodiments based on the first embodiment, referring to Figure 1 The blood collection tube 10 further comprises a tube cover 500, which is wrapped on the outer side of the rubber plug 400 and is provided with a through hole corresponding to the position of the groove.

[0078] In some embodiments based on the first embodiment, referring to Figure 1 The first accommodating portion 110 is in interference fit with the outer tube 200 at the end of the first inner cavity 101 having the opening. Thus, when there is a gap 11 between the first side portion 112 and the outer tube 200, the gap 11 can be closed, so that the sample cannot enter the gap 11.

[0079] When the leading end of the first accommodating portion 110 having the opening is in interference fit with the outer tube 200, in some embodiments, the first accommodating portion 110 further comprises an annular flange 113, which is arranged on the outer surface 211b of the first side portion 112, for realizing the interference fit between the first accommodating portion 110 and the outer tube 200. By arranging the annular flange 113 in interference fit with the outer tube, the wall thickness of the first accommodating portion 110 can be kept uniform, thereby further reducing the design and production costs. For example, the upper end surface of the annular flange 113 is flush with the upper end surface of the first side portion 112.

[0080] In other embodiments, the first accommodating portion 110 can not be additionally provided with the annular flange 113 protruding obviously, but the outer diameter of the first accommodating portion 110 is arranged to gradually decrease from the leading end to the trailing end, that is, the wall thickness of the first accommodating portion 110 gradually decreases from the leading end to the trailing end, and the portion with the largest outer diameter is in interference fit with the outer tube 200.

[0081] On the basis of the first embodiment, in some embodiments, the inner tube 100 is made of a first material, and the outer tube 200 is made of a second material, the first material being different from the second material. Specifically, the first material is polypropylene (PP), and the second material is polyethylene terephthalate (PET), wherein some blood collection tubes 10 have liquid additives pre-placed in the first inner cavity 101. Polypropylene has good water retention performance, which can slow down the loss of water in the additives, thereby prolonging the effective period of the blood collection tube 10. Polyethylene terephthalate has good air isolation performance, which can ensure the sealing effect of the first inner cavity 101.

[0082] On the basis of the first embodiment, in some embodiments, the wall thickness of the first side portion 112 is substantially uniform, thereby being more convenient for production. It should be noted that the “substantially uniform wall thickness” referred to herein includes the case of complete uniformity or negligible wall thickness variation under normal detection conditions. The “negligible wall thickness variation” referred to later is usually caused by production errors and other factors.

[0083] On the basis of the first embodiment, in some embodiments, the inner diameter of the first accommodating portion 110 is greater than or equal to 6 mm and less than or equal to 7.5 mm in the axial extension range of the first side portion 112. For example, the inner diameter of the first accommodating portion 110 is 6.1 mm, 6.3 mm, 6.5 mm, 6.7 mm, 6.9 mm, 7.1 mm, 7.3 mm, etc. By limiting the inner diameter of the first accommodating portion 110, the volume of the first inner cavity 101 can be conveniently controlled.

[0084] On the basis of the first embodiment, in some embodiments, the outer diameter of the outer tube 200 is greater than or equal to 12 mm and less than or equal to 13 mm. For example, the outer diameter of the outer tube 200 is 12.1 mm, 12.2 mm, 12.3 mm, 12.4 mm, 12.5 mm, 12.6 mm, 12.7 mm, 12.8 mm, 12.9 mm, etc. By limiting the outer diameter of the outer tube 200, the outer tube 200 can be adapted to common sample racks.

[0085] On the basis of the first embodiment, in some embodiments, the ratio of the inner diameter of the first accommodating portion 110 to the outer diameter of the outer tube 200 in the axial extension range of the first side portion 112 is greater than or equal to 0.5 and less than or equal to 0.63, and for example, the ratio is 0.51, 0.53, 0.55, 0.57, 0.59, 0.61, etc. By limiting the ratio of the inner diameter of the first accommodating portion 110 to the outer diameter of the outer tube 200, the common outer tube 200 can be adapted, and the volume of the first inner cavity 101 can be conveniently controlled. It should be noted that in the present embodiment, the ratio can be calculated by selecting a plane perpendicular to the axial direction of the inner tube 100 or the outer tube 200, cutting the blood collection tube at the plane to obtain the inner diameter of the first accommodating portion 110 and the outer diameter of the outer tube 200 on the cutting surface, and then obtaining the ratio. It should be noted that the ratio obtained according to different cutting surfaces can be the same or different.

[0086] On the basis of the first embodiment, in some embodiments, the distance is greater than or equal to 10 mm, and for example, the distance is 11 mm, 12 mm, 13 mm, 14 mm, 15 mm, 16 mm, etc. The lengths of the outer tubes 200 of the common manufacturers are usually the same or similar. By limiting the length of the distance, the length of the first accommodating portion 110 can be limited, and thus the volume of the first inner cavity 101 can be conveniently controlled.

[0087] On the basis of the first embodiment, in some embodiments, the ratio of the length of the outer tube 200 to the length of the first accommodating portion 110 is greater than or equal to 1.3 and less than or equal to 2, and for example, the ratio is 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, etc. The lengths of the outer tubes 200 of the common manufacturers are usually the same or similar. By limiting the ratio of the lengths, the length of the first accommodating portion 110 can be limited, and thus the volume of the first inner cavity 101 can be conveniently controlled. It should be noted that in the present embodiment, the length is measured from the maximum axial length of the inner tube 100 or the outer tube 200 from the first end to the tail end.

[0088] On the basis of the first embodiment, in some embodiments, the volume of the first inner cavity 101 is not greater than 2.5 ml, and for example, the volume of the first inner cavity 101 is 2.4 ml, 2.3 ml, 2.2 ml, 2.1 ml, 2.0 ml, 1.9 ml, etc. By limiting the volume of the first inner cavity 101, the storage of trace blood can be adapted.

[0089] On the basis of the first embodiment, in some embodiments, the outer tube 200 comprises a second accommodating portion 210, the second accommodating portion 210 comprises a second bottom portion 211 and a second side portion 212, the second side portion 212 is connected to the second bottom portion 211, and the two together form the aforementioned second inner cavity 201. The second accommodating portion 210 can be understood with reference to the foregoing embodiments.

[0090] In the second embodiment, the inner diameter of the second accommodating portion 210 is substantially uniform in the axial extension range of the second side portion, and when the outer diameter of the first accommodating portion 110 of the inner tube 100 is substantially uniform and the gap 11 between the first accommodating portion 110 and the outer tube 200 is provided, the cross-sectional area of the gap 11 is substantially constant. It should be noted that the "substantially uniform" referred to herein includes the case of complete uniformity or the presence of an ignorable inner diameter variation under normal detection conditions. The "ignorable inner diameter variation" referred to later is usually caused by production errors, draft angles, and the like. In some embodiments, the wall thickness of the second side portion 212 is substantially uniform. It should be noted that the "wall thickness is substantially uniform" referred to herein includes the case of complete uniformity or the presence of an ignorable wall thickness variation under normal detection conditions. The "ignorable wall thickness variation" referred to later is usually caused by production errors and the like.

[0091] The second embodiment of the utility model further provides a blood collection tube, which refers to Figure 3 which comprises an inner tube 100 and an outer tube 200, wherein the outer tube 200 can be a conventional constant tube which can be placed on a sample rack for transfer. The inner tube 100 is a micro tube which can be accommodated in the outer tube 200, so that the micro tube can also be loaded through the sample rack by taking the outer tube 200 as a carrier. It should be noted that the shape of the inner tube 100 can be adaptively designed according to the shape of the outer tube 200, so that the stable placement of the inner tube 100 is realized without changing the outer tube 200.

[0092] In the second embodiment, the outer tube 200 can be understood with reference to the first embodiment, and the inner tube 100 comprises a first bottom portion 111 and a first side portion 112, the first side portion 112 is connected to the first bottom portion 111, and the two together define the aforementioned first inner cavity 101 which is open at one end. The difference between the second embodiment and the first embodiment includes: in the first embodiment, the inner diameter of the first accommodating portion 110 is substantially uniform in the axial extension range of the first side portion 112, while in the second embodiment, the inner diameter of the first accommodating portion 110 gradually decreases in the axial extension range of the first side portion 112 and in the direction from the end of the second inner cavity 201 which is open to the tail end of the outer tube 200 (for example Figure 3 the direction from top to bottom). Since the first side portion 112 and the first bottom portion 111 together define the first inner cavity 101, that is, the first side portion 112 extends to the first opening, it can be considered that the inner diameter of the part of the first accommodating portion 110 other than the first bottom portion 111 as a whole presents a gradually decreasing effect. Compared with the inner tube having an equal diameter section and a variable diameter section, it does not need to be customized for the mold and the corresponding production process, so the design cost and the production cost can be reduced.

[0093] On the basis of the second embodiment, in some embodiments,Figure 3 The blood collection tube 10 further comprises a support portion 300, the inner tube 100 is supported by the support portion 300 to set a distance between the first bottom 111 and the tail end of the outer tube 200. As mentioned above, the outer tube 200 is a constant tube, the volume of the second inner cavity 201 is large, and the length is also long. The inner tube 100 is supported by the support portion 300 to set a distance H between the first bottom 111 and the tail end of the outer tube 200. In this way, the length of the inner tube 100 can be reduced without changing the length of the outer tube 200, thereby reducing the volume of the first inner cavity 101 of the inner tube 100. The distance should be set so that the volume of the first inner cavity 101 is suitable for injecting a small amount of blood. For example, by setting the support portion 300 to shorten the length of the inner tube 100, the volume of the first inner cavity 101 is 2ml. When 1ml is drawn from the first inner cavity 101 (so as to accommodate 1ml of blood), the air pressure in the first inner cavity 101 will decrease significantly, thereby facilitating smooth injection of blood. It should be noted that the "distance between the first bottom 111 and the tail end of the outer tube 200" specifically refers to the distance between the farthest point of the first bottom 111 away from the first opening and the farthest point of the tail end of the outer tube 200. For example, when the first bottom 111 is an arc-shaped bottom protruding downward as shown in Figure 3 For example, when the tail end of the outer tube 200 is an arc-shaped tail end protruding downward as shown in Figure 3 For the convenience of understanding, the distance H is also roughly identified by a dashed line in Figure 1 For the convenience of understanding, the distance H is also roughly identified by a dashed line in

[0094] When the blood collection tube 10 further comprises the support portion 300, in some embodiments, with reference to Figure 1 The support portion 300 is a part of the inner tube 100, one end of which is connected to the first bottom 111 of the first containing portion 110, and the other end extends to the tail end of the outer tube 200 and abuts against the outer tube 200. For example, the support portion 300 is a hollow tubular structure, the outer diameter of which is equal to or less than the outer diameter of the first containing portion 110, and the tail end of the support portion 300 abuts against the bottom of the outer tube 200. For example, the support portion 300 can also be a solid columnar structure, the center of which is connected to the first bottom 111. For example, the support portion 300 can also comprise a plurality of sub-support portions distributed along the circumference of the first containing portion 110.

[0095] When the blood collection tube 10 further comprises the support portion 300, in some embodiments, with reference to Figure 2, the support part 300 is a part of the outer tube 200, specifically, the outer tube 200 comprises a second accommodating part 210, the second accommodating part 210 comprises a second bottom part 211 and a second side part 212, the second side part 212 is connected to the second bottom part 211, and the two together surround the aforementioned second inner cavity 201. It should be noted that the second bottom part 211 should be understood according to the usual meaning, that is, located at the tail end (or called bottom end) of the outer tube 200 and constitutes the bottom of the second inner cavity 201. In order to further assist understanding, the range of the second bottom part 211 and the second side part 212 is roughly indicated by a dashed line in Figure 2 , for example, the second bottom part 211 presents an arc-shaped bottom part that protrudes downward, the second side part 212 presents a cylindrical structure, and the lower end of the second side part 212 is connected to the upper end of the second bottom part 211; for example, the second side part 212 is tangent to the upper end of the second bottom part 211, and the tangent position of the two can be regarded as the boundary of the two.

[0096] In the embodiment, the second bottom part 211 is provided as the support part 300, that is, the support part 300 and the second bottom part 211 are the same structure, the second bottom part 211 has an inner surface 211a provided towards the opening of the second inner cavity 201 and an outer surface 211b provided away from the opening, for example, the inner surface 211a is the upper surface in Figure 2 , and the outer surface 211b is the lower surface in Figure 2 . The axial distance between the nearest point of the inner surface 211a closest to the outer surface 211b and the farthest point of the outer surface 211b farthest from the inner surface 211a is equal to the aforementioned set distance H, in other words, compared with the embodiment shown in Figure 1 , the bottom of the outer tube 200 is thickened in this embodiment, and the inner tube 100 is supported by the thickened part. For example, when the blood collection tube 10 is placed vertically, the nearest point of the inner surface 211a closest to the outer surface 211b is the lowest point of the inner surface 211a, and the farthest point of the outer surface 211b farthest from the inner surface 211a is the lowest point of the outer surface 211b. In addition, the first bottom part 111 at least abuts the nearest point of the inner surface 211a of the second bottom part 211, so that the first bottom part 111 and the tail end of the outer tube 200 are also separated by the aforementioned set distance H.

[0097] It should be noted that the farthest point of the outer surface 211b farthest from the inner surface 211a is not limited to the center point of the outer surface 211b, nor is it limited to one point, for example, the outer surface 211b of the second bottom part 211 is provided with a groove that does not penetrate through, at this time, each point of the edge of the groove can be regarded as the farthest point of the outer surface 211b farthest from the inner surface 211a. Figure 2

[0098] ​In some embodiments, the support 300 can be independent of the inner tube 100 and the outer tube 200.

[0099] In some embodiments, the first side 112 of the inner tube 100 is spaced apart from the outer tube 200. Figure 3 In some embodiments, the first side 112 of the inner tube 100 is spaced apart from the outer tube 200, and the gap 11 can reduce the outer diameter of the inner tube 100, and accordingly, the inner diameter of the inner tube 100, so as to reduce the volume of the first inner cavity 101. The size of the gap 11 should be such that the volume of the first inner cavity 101 is suitable for the injection of a small amount of blood, and the first inner cavity 101 is not too small to be inserted into the injection needle and the probability of the injection needle touching the inner wall is reduced.

[0100] In some embodiments, when the first side 112 of the inner tube 100 is spaced apart from the outer tube 200, the air pressure in the gap 11 is less than the atmospheric pressure, so as to reduce or eliminate the leakage of the gas in the gap 11 into the first inner cavity 101, thereby prolonging the effective period of the blood collection tube 10. Specifically, when the air pressure in the gap 11 is less than the atmospheric pressure and less than or equal to the air pressure in the first inner cavity 101, the gas in the gap 11 will not leak into the first inner cavity 101. When the air pressure in the gap 11 is less than the atmospheric pressure and greater than the air pressure in the first inner cavity 101, even if the gas in the gap 11 leaks into the first inner cavity 101 due to the pressure difference, the pressure difference can be reduced compared to the case where the air pressure in the gap 11 is equal to the atmospheric pressure, and thus the leakage amount is reduced.

[0101] In some embodiments, the first side 112 of the inner tube 100 is spaced apart from the outer tube 200. Figure 3 In some embodiments, the blood collection tube 10 further comprises a rubber plug 400, which is elastic and easy to be pierced by the injection needle. At least a portion of the rubber plug 400 is inserted into the outer tube 200, so as to directly seal the second opening and make the second inner cavity 201 in a sealed state. In some specific embodiments, the portion of the rubber plug 400 in the outer tube 200 can abut against the leading end of the inner tube 100, so as to directly seal the first opening and make the first inner cavity 101 in a sealed state. In other specific embodiments, the portion of the rubber plug 400 in the outer tube 200 does not directly abut against the leading end of the inner tube 100, but forms a sealing relationship between the leading end of the inner tube 100 and the inner wall of the outer tube 200, so as to also make the first inner cavity 101 in a sealed state.

[0102] In some specific embodiments, an unpenetrated groove is formed on the end of the rubber plug 400 away from the outer tube 200 (e.g., the upper end in the drawings), which can reduce the thickness of this portion of the rubber plug 400 in the axial direction of the outer tube 200, so as to reduce the resistance when the injection needle passes through the rubber plug 400. Since the groove is unpenetrated, the sealing effect can be ensured.

[0103] On the basis of the second embodiment, in some embodiments, referring to Figure 3 The blood collection tube 10 further comprises a tube cover 500, which is wrapped outside the rubber plug 400 and has a through hole corresponding to the position of the groove.

[0104] On the basis of the second embodiment, in some embodiments, referring to Figure 3 The first accommodating portion 110 is in interference fit with the outer tube 200 at the end with the opening of the first inner cavity 101, so that when there is a gap 11 between the first side portion 112 and the outer tube 200, the gap 11 can be closed to prevent the sample from entering the gap 11.

[0105] When the first end of the first accommodating portion 110 with the opening is in interference fit with the outer tube 200, in some specific embodiments, the first accommodating portion 110 further comprises an annular flange 113, which is arranged on the outer surface 211b of the first side portion 112 for interference fit between the first accommodating portion 110 and the outer tube 200. By arranging the annular flange 113 in interference fit with the outer tube, the wall thickness of the first accommodating portion 110 can be kept consistent, further reducing the design and production cost. For example, the upper end surface of the annular flange 113 is flush with the upper end surface of the first side portion 112.

[0106] In other specific embodiments, referring to Figure 3 The first accommodating portion 110 can also not be additionally provided with an obvious annular flange 113, but the outer diameter of the first accommodating portion 110 is arranged to gradually decrease from the first end to the tail end. In the case that the wall thickness of the first accommodating portion 110 is kept consistent as a whole, the part with the largest outer diameter is in interference fit with the outer tube 200.

[0107] On the basis of the second embodiment, in some embodiments, the inner tube 100 is made of a first material, the outer tube 200 is made of a second material, and the first material is different from the second material. Specifically, the first material is polypropylene (PP), and the second material is polyethylene terephthalate (PET). In some blood collection tubes 10, a liquid additive is pre-placed in the first inner cavity 101. Polypropylene has good water retention performance, which can slow down the loss of water in the additive, thereby prolonging the effective period of the blood collection tube 10. Polyethylene terephthalate has good air isolation performance, which can ensure the sealing effect in the first inner cavity 101.

[0108] On the basis of the second embodiment, in some embodiments, the wall thickness of the first side portion 112 is substantially consistent, thereby being more convenient for production. It should be noted that the "substantially consistent wall thickness" referred to herein includes the case of complete consistency or negligible wall thickness variation under normal detection conditions. The "negligible wall thickness variation" referred to later is usually caused by production errors and other factors.

[0109] On the basis of the second embodiment, in some embodiments, the inner diameter of the first accommodating portion 110 is greater than or equal to 6 mm and less than or equal to 7.5 mm in the axial extension range of the first side portion 112. For example, the inner diameter of the first accommodating portion 110 is 6.1 mm, 6.3 mm, 6.5 mm, 6.7 mm, 6.9 mm, 7.1 mm, 7.3 mm, or the like. By limiting the inner diameter of the first accommodating portion 110, the volume of the first inner cavity 101 can be controlled. It should be noted that, in the present embodiment, the inner diameter of the first accommodating portion 110 being greater than or equal to 6 mm and less than or equal to 7.5 mm means that the minimum inner diameter of the first accommodating portion 110 is greater than or equal to 6 mm and less than or equal to 7.5 mm, and the maximum inner diameter of the first accommodating portion 110 is also greater than or equal to 6 mm and less than or equal to 7.5 mm.

[0110] On the basis of the second embodiment, in some embodiments, the outer diameter of the outer tube 200 is greater than or equal to 12 mm and less than or equal to 13 mm. For example, the outer diameter of the outer tube 200 is 12.1 mm, 12.2 mm, 12.3 mm, 12.4 mm, 12.5 mm, 12.6 mm, 12.7 mm, 12.8 mm, 12.9 mm, or the like. By limiting the outer diameter of the outer tube 200, the outer tube 200 can be adapted to common sample racks. It should be noted that, when the outer diameter of the outer tube 200 also gradually decreases from the first end to the second end, the outer diameter of the outer tube 200 being greater than or equal to 12 mm and less than or equal to 13 mm means that the minimum outer diameter of the outer tube 200 is greater than or equal to 12 mm and less than or equal to 13 mm, and the maximum outer diameter of the outer tube 200 is also greater than or equal to 12 mm and less than or equal to 13 mm.

[0111] On the basis of the second embodiment, in some embodiments, the ratio of the inner diameter of the first accommodating portion 110 to the outer diameter of the outer tube 200 is greater than or equal to 0.5 and less than or equal to 0.63 in the axial extension range of the first side portion 112. For example, the ratio is 0.51, 0.53, 0.55, 0.57, 0.59, 0.61, or the like. By limiting the ratio of the inner diameter of the first accommodating portion 110 to the outer diameter of the outer tube 200, the outer tube 200 can be adapted to common sample racks, and the volume of the first inner cavity 101 can be controlled. It should be noted that, in the present embodiment, the ratio of the inner diameter of the first accommodating portion 110 to the outer diameter of the outer tube 200 can be calculated by selecting a plane perpendicular to the axial direction of the inner tube 100 or the outer tube 200, cutting the blood collection tube at the plane to obtain the inner diameter of the first accommodating portion 110 and the outer diameter of the outer tube 200 on the cutting surface, and then obtaining the ratio. It should be further noted that, the ratio obtained according to different cutting surfaces can be the same or different.

[0112] On the basis of the second embodiment, in some embodiments, the set distance is greater than or equal to 10 mm, and exemplary set distances are 11 mm, 12 mm, 13 mm, 14 mm, 15 mm, 16 mm, etc. The lengths of the outer tubes 200 of common manufacturers are usually the same or similar, and by limiting the length of the set distance, the length of the first accommodating portion 110 can be limited, thereby facilitating control of the volume of the first inner cavity 101.

[0113] On the basis of the second embodiment, in some embodiments, the ratio of the length of the outer tube 200 to the length of the first accommodating portion 110 is greater than or equal to 1.3 and less than or equal to 2, and exemplary ratios are 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, etc. The lengths of the outer tubes 200 of common manufacturers are usually the same or similar, and by limiting the ratio of the lengths, the length of the first accommodating portion 110 can be limited, thereby facilitating control of the volume of the first inner cavity 101. It should be noted that in this embodiment, the length is measured as the maximum axial length from the first end to the tail end of the inner tube 100 or the outer tube 200.

[0114] On the basis of the second embodiment, in some embodiments, the volume of the first inner cavity 101 is not greater than 2.5 ml, and exemplary volumes are 2.4 ml, 2.3 ml, 2.2 ml, 2.1 ml, 2.0 ml, 1.9 ml, etc. By limiting the volume of the first inner cavity 101, it can be adapted to store a small amount of blood.

[0115] On the basis of the second embodiment, in some embodiments, the outer tube 200 includes a second accommodating portion 210, the second accommodating portion 210 includes a second bottom portion 211 and a second side portion 212, the second side portion 212 is connected to the second bottom portion 211, and the two together form the aforementioned second inner cavity 201. The second accommodating portion 210 can be understood with reference to the foregoing embodiments.

[0116] In this embodiment, the inner diameter of the second accommodating portion 210 is substantially uniform within the axial extension range of the second side portion. When the outer diameter of the first accommodating portion 210 of the inner tube 100 is substantially uniform, and there is a gap 11 between the first accommodating portion 110 and the outer tube 200, the cross-sectional area of the gap 11 remains substantially constant. It should be noted that the term "substantially uniform" as used herein includes the case where it is completely uniform or there is a negligible change in the inner diameter under normal detection conditions. The term "negligible change in the inner diameter" as used later is usually caused by production errors, draft angles, etc. In some specific embodiments, the wall thickness of the second side portion 212 is substantially uniform. It should be noted that the term "substantially uniform wall thickness" as used herein includes the case where it is completely uniform or there is a negligible change in the wall thickness under normal detection conditions. The term "negligible change in the wall thickness" as used later is usually caused by production errors, etc.

[0117] The third embodiment of the utility model also proposes a blood collection tube, which comprises an inner tube 100 and an outer tube 200, wherein the outer tube 200 can be a conventional constant tube, which can be placed on a sample rack for transfer. The inner tube 100 is a micro tube, which can be accommodated in the outer tube 200, so that the micro tube can also be loaded through the sample rack by taking the outer tube 200 as a carrier. It should be noted that the shape of the inner tube 100 can be adaptively designed according to the shape of the outer tube 200, so that the stable placement of the inner tube 100 is realized without changing the outer tube 200.

[0118] In the embodiment, the outer tube 200 can be understood with reference to the first embodiment, the inner tube 100 comprises a first bottom 111 and a first side 112, the first side 112 is connected to the first bottom 111, and the two together define the aforementioned first inner cavity 101 which is open at one end. The inner tube 100 can be understood with reference to the aforementioned first embodiment, or can be understood with reference to the aforementioned second embodiment, or can be other forms of inner tube 100, such as an inner tube with a constant diameter section and a variable diameter section. In the embodiment, the first side 112 has a gap 11 with the outer tube 200, the existence of the gap 11 can reduce the outer diameter of the inner tube 100, and correspondingly reduce the inner diameter of the inner tube 100, thereby reducing the volume of the first inner cavity 101. The size of the gap 11 should be such that the volume of the first inner cavity 101 is suitable for injecting a small amount of blood, and at the same time, the first inner cavity 101 is not too small to be suitable for inserting a liquid injection needle, and the probability of the liquid injection needle touching the inner wall is reduced.

[0119] In addition, in the embodiment, the air pressure in the gap 11 is less than the atmospheric pressure, so that the leakage of the gas in the gap 11 into the first inner cavity 101 can be reduced or eliminated, thereby making the blood collection tube 10 have a longer effective period. Specifically, when the air pressure in the gap 11 is less than the atmospheric pressure and less than or equal to the air pressure in the first inner cavity 101, the gas in the gap 11 will not leak into the first inner cavity 101. When the air pressure in the gap 11 is less than the atmospheric pressure and greater than the air pressure in the first inner cavity 101, even if the gas in the gap 11 leaks into the first inner cavity 101 due to the pressure difference, compared with the case where the air pressure in the gap 11 is equal to the atmospheric pressure, the pressure difference can be reduced, and the leakage amount can be reduced.

[0120] On the basis of the third embodiment, in some embodiments, with reference to Figure 1 , Figure 2, the blood collection tube 10 further comprises a support portion 300, the outer tube 200 supports the inner tube 100 through the support portion 300, so that the first bottom 111 is spaced apart from the tail end of the outer tube 200 by a set distance, as described above, the outer tube 200 is a constant tube, the volume of the second inner cavity 201 is large, and the length is also relatively long, and the inner tube 100 is supported by the support portion 300 to be spaced apart from the tail end of the outer tube 200 by a set distance H. In this way, the length of the inner tube 100 can be reduced without changing the length of the outer tube 200, thereby reducing the volume of the first inner cavity 101 of the inner tube 100. The set distance should be such that the volume of the first inner cavity 101 is suitable for injecting a small amount of blood. For example, by setting the support portion 300 to shorten the length of the inner tube 100, the volume of the first inner cavity 101 is 2ml, when 1ml is drawn from the first inner cavity 101 (so as to accommodate 1ml of blood), the air pressure of the first inner cavity 101 will decrease significantly, thereby facilitating smooth injection of blood. It should be noted that the "distance between the first bottom 111 and the tail end of the outer tube 200" referred to here specifically refers to the distance between the farthest point of the first bottom 111 away from the first opening and the farthest point of the tail end of the outer tube 200. For example, when the first bottom 111 is an arc-shaped bottom that protrudes downward as shown in Figure 1 , the farthest point is specifically the lowest point. Similarly, when the tail end of the outer tube 200 is an arc-shaped tail end that protrudes downward as shown in Figure 1 , the farthest point is specifically the lowest point. For the convenience of understanding, Figure 1 , the set distance H is also roughly identified by a dashed line.

[0121] When the blood collection tube 10 further comprises the support portion 300, in some embodiments, with reference to Figure 1 , the support portion 300 is a part of the inner tube 100, one end of which is connected to the first bottom 111 of the first containing portion 110, and the other end extends to the tail end of the outer tube 200 and abuts against the outer tube 200. For example, the support portion 300 is a hollow tubular structure, the outer diameter of which is equal to or less than the outer diameter of the first containing portion 110, and the tail end of the support portion 300 abuts against the bottom of the outer tube 200. For example, the support portion 300 can also be a solid columnar structure, which is connected to the center of the first bottom 111. For example, the support portion 300 can also comprise a plurality of sub-support portions spaced apart along the circumference of the first containing portion 110.

[0122] When the blood collection tube 10 further comprises the support portion 300, in some embodiments, with reference to Figure 2, the support part 300 is a part of the outer tube 200, specifically, the outer tube 200 comprises a second accommodating part 210, the second accommodating part 210 comprises a second bottom part 211 and a second side part 212, the second side part 212 is connected to the second bottom part 211, and the two together surround the aforementioned second inner cavity 201. It should be noted that the second bottom part 211 should be understood according to the usual meaning, that is, located at the tail end (or called bottom end) of the outer tube 200 and constitutes the bottom of the second inner cavity 201. In order to further assist understanding, the range of the second bottom part 211 and the second side part 212 is roughly indicated by a dashed line in Figure 2 , for example, the second bottom part 211 presents an arc-shaped bottom part that protrudes downward, the second side part 212 presents a cylindrical structure, and the lower end of the second side part 212 is connected to the upper end of the second bottom part 211; for example, the second side part 212 is tangent to the upper end of the second bottom part 211, and the tangent position of the two can be regarded as the boundary of the two.

[0123] In this embodiment, the second bottom part 211 is provided as the support part 300, that is, the support part 300 and the second bottom part 211 are the same structure, the second bottom part 211 has an inner surface 211a provided towards the opening of the second inner cavity 201 and an outer surface 211b provided away from the opening, for example, the inner surface 211a is the upper surface in Figure 2 , and the outer surface 211b is the lower surface in Figure 2 . The axial distance between the nearest point of the inner surface 211a closest to the outer surface 211b and the farthest point of the outer surface 211b farthest from the inner surface 211a is equal to the aforementioned set distance H, in other words, compared with the embodiment shown in Figure 1 , the bottom of the outer tube 200 is thickened in this embodiment, and the inner tube 100 is supported by the thickened part. For example, when the blood collection tube 10 is placed vertically, the nearest point of the inner surface 211a closest to the outer surface 211b is the lowest point of the inner surface 211a, and the farthest point of the outer surface 211b farthest from the inner surface 211a is the lowest point of the outer surface 211b. In addition, the first bottom part 111 at least abuts the nearest point of the inner surface 211a of the second bottom part 211, so that the first bottom part 111 and the tail end of the outer tube 200 are also separated by the aforementioned set distance H.

[0124] It should be noted that the farthest point of the outer surface 211b farthest from the inner surface 211a is not limited to the center point of the outer surface 211b, nor is it limited to one point, for example, the outer surface 211b of the second bottom part 211 is provided with a groove that does not penetrate through, at this time, each point of the edge of the groove can be regarded as the farthest point of the outer surface 211b farthest from the inner surface 211a. Figure 2

[0125] ​In some embodiments, the support 300 can be a component independent of the inner tube 100 and the outer tube 200.

[0126] In some embodiments, the support 300 can be a component independent of the inner tube 100 and the outer tube 200. Figure 1 、 Figure 2 In some embodiments, the blood collection tube 10 further comprises a rubber plug 400, which is elastic and easy to be punctured by the injection needle. At least a portion of the rubber plug 400 is inserted into the outer tube 200, thereby directly sealing the second opening, so that the second inner cavity 201 is in a sealed state. In some specific embodiments, the portion of the rubber plug 400 in the outer tube 200 can abut against the leading end of the inner tube 100, thereby directly sealing the first opening, so that the first inner cavity 101 is in a sealed state. In other specific embodiments, the portion of the rubber plug 400 in the outer tube 200 does not directly abut against the leading end of the inner tube 100, but forms a sealing relationship between the leading end of the inner tube 100 and the inner wall of the outer tube 200. In this way, the first inner cavity 101 can also be in a sealed state.

[0127] In some specific embodiments, an unpenetrated groove is formed on the end of the rubber plug 400 away from the outer tube 200 (e.g., the upper end in the figure). The groove can reduce the thickness of the rubber plug 400 in the axial direction of the outer tube 200, thereby reducing the resistance when the injection needle passes through the rubber plug 400. At the same time, since the groove is not penetrated, the sealing effect can be ensured.

[0128] In some embodiments, the support 300 can be a component independent of the inner tube 100 and the outer tube 200. Figure 1 、 Figure 2 In some embodiments, the blood collection tube 10 further comprises a tube cover 500, which is wrapped on the outer side of the rubber plug 400 and is provided with a through hole corresponding to the position of the groove.

[0129] In some embodiments, the support 300 can be a component independent of the inner tube 100 and the outer tube 200. Figure 1 、 Figure 2 In some embodiments, the support 300 can be a component independent of the inner tube 100 and the outer tube 200.

[0130] In some specific embodiments, when the leading end of the first accommodating portion 110 with the opening is in interference fit with the outer tube 200, the first accommodating portion 110 further comprises an annular flange 113, which is arranged on the outer surface 211b of the first side portion 112 and used for interference fit between the first accommodating portion 110 and the outer tube 200. By arranging the annular flange 113 in interference fit with the outer tube, the wall thickness of the first accommodating portion 110 can be kept consistent, thereby further reducing the design and production costs. For example, the upper end surface of the annular flange 113 is flush with the upper end surface of the first side portion 112.

[0131] In some embodiments, the first accommodating portion 110 can not be additionally provided with the obvious annular flange 113, but the outer diameter of the first accommodating portion 110 is gradually reduced from the first end to the second end, and the part with the largest outer diameter is in interference fit with the outer tube 200.

[0132] On the basis of the third embodiment, in some embodiments, the inner tube 100 is made of a first material, and the outer tube 200 is made of a second material, and the first material is different from the second material. Specifically, the first material is polypropylene (PP), and the second material is polyethylene terephthalate (PET), wherein some blood collection tubes 10 have liquid additives pre-placed in the first inner cavity 101. Polypropylene has good water retention performance, which can slow down the loss of water in the additives, thereby prolonging the effective period of the blood collection tube 10. Polyethylene terephthalate has good air isolation performance, which can guarantee the sealing effect in the first inner cavity 101.

[0133] On the basis of the third embodiment, in some embodiments, the wall thickness of the first side portion 112 is substantially uniform, thereby being more convenient for production. It needs to be noted that the “substantially uniform wall thickness” herein includes the case of completely uniform or negligible wall thickness variation under normal detection conditions. The “negligible wall thickness variation” in the following description is usually caused by production errors and other factors.

[0134] On the basis of the third embodiment, in some embodiments, the inner diameter of the first accommodating portion 110 is greater than or equal to 6 mm and less than or equal to 7.5 mm in the axial extension range of the first side portion 112. For example, the inner diameter of the first accommodating portion 110 is 6.1 mm, 6.3 mm, 6.5 mm, 6.7 mm, 6.9 mm, 7.1 mm, 7.3 mm, etc. By limiting the inner diameter of the first accommodating portion 110, the volume of the first inner cavity 101 can be controlled.

[0135] On the basis of the third embodiment, in some embodiments, the outer diameter of the outer tube 200 is greater than or equal to 12 mm and less than or equal to 13 mm. For example, the outer diameter of the outer tube 200 is 12.1 mm, 12.2 mm, 12.3 mm, 12.4 mm, 12.5 mm, 12.6 mm, 12.7 mm, 12.8 mm, 12.9 mm, etc. By limiting the outer diameter of the outer tube 200, the outer tube 200 can be adapted to common sample racks.

[0136] On the basis of the third embodiment, in some embodiments, the ratio of the inner diameter of the first accommodating portion 110 to the outer diameter of the outer tube 200 in the axial extension range of the first side portion 112 is greater than or equal to 0.5 and less than or equal to 0.63, and for example, the ratio is 0.51, 0.53, 0.55, 0.57, 0.59, 0.61, etc. By limiting the ratio of the inner diameter of the first accommodating portion 110 to the outer diameter of the outer tube 200, the common outer tube 200 can be adapted, and the volume of the first inner cavity 101 can be conveniently controlled. It should be noted that in the present embodiment, the ratio can be calculated by selecting a plane perpendicular to the axial direction of the inner tube 100 or the outer tube 200, cutting the blood collection tube at the plane to obtain the inner diameter of the first accommodating portion 110 and the outer diameter of the outer tube 200 on the cutting surface, and then obtaining the ratio. It should be noted that the ratio obtained according to different cutting surfaces can be the same or different.

[0137] On the basis of the third embodiment, in some embodiments, the distance is greater than or equal to 10 mm, and for example, the distance is 11 mm, 12 mm, 13 mm, 14 mm, 15 mm, 16 mm, etc. The lengths of the outer tubes 200 of the common manufacturers are usually the same or similar. By limiting the length of the distance, the length of the first accommodating portion 110 can be limited, and thus the volume of the first inner cavity 101 can be conveniently controlled.

[0138] On the basis of the third embodiment, in some embodiments, the ratio of the length of the outer tube 200 to the length of the first accommodating portion 110 is greater than or equal to 1.3 and less than or equal to 2, and for example, the ratio is 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, etc. The lengths of the outer tubes 200 of the common manufacturers are usually the same or similar. By limiting the ratio of the lengths, the length of the first accommodating portion 110 can be limited, and thus the volume of the first inner cavity 101 can be conveniently controlled. It should be noted that in the present embodiment, the length is measured from the maximum axial length of the inner tube 100 or the outer tube 200 from the first end to the second end.

[0139] On the basis of the third embodiment, in some embodiments, the volume of the first inner cavity 101 is not greater than 2.5 ml, and for example, the volume of the first inner cavity 101 is 2.4 ml, 2.3 ml, 2.2 ml, 2.1 ml, 2.0 ml, 1.9 ml, etc. By limiting the volume of the first inner cavity 101, the storage of trace blood can be adapted.

[0140] On the basis of the third embodiment, in some embodiments, the outer tube 200 comprises a second accommodating portion 210, the second accommodating portion 210 comprises a second bottom portion 211 and a second side portion 212, the second side portion 212 is connected to the second bottom portion 211, and the second bottom portion 211 and the second side portion 212 together form the second inner cavity 201. The second accommodating portion 210 can be understood with reference to the foregoing embodiments.

[0141] In the embodiment, the inner diameter of the second accommodating portion 210 is substantially uniform in the axial extension range of the second side portion, and when the outer diameter of the first accommodating portion 110 of the inner tube 100 is substantially uniform and the first accommodating portion 110 has a gap 11 with the outer tube 200, the sectional area of the gap 11 is substantially constant. It should be noted that the "substantially uniform" referred to herein includes the case of complete uniformity or existence of negligible inner diameter variation under normal detection conditions. The "negligible inner diameter variation" referred to later is usually caused by production errors, draft angles, and the like. In some embodiments, the wall thickness of the second side portion 212 is substantially uniform. It should be noted that the "wall thickness substantially uniform" referred to herein includes the case of complete uniformity or existence of negligible wall thickness variation under normal detection conditions. The "negligible wall thickness variation" referred to later is usually caused by production errors and the like.

[0142] The fourth embodiment of the utility model further provides a sample analysis system, the sample analysis system includes sample needle mechanism, sensing mechanism, controller, reagent needle mechanism and detection mechanism, sample needle mechanism includes sample needle and drive mechanism, sample needle is installed in drive mechanism, drive mechanism is used for controlling sample needle to suck sample from blood collection tube 10, sensing mechanism is used for detecting the interface position of blood plasma and blood cell in blood collection tube 10, controller is used for controlling the needle height of sample needle and sample suction speed according to the detection signal of sensing mechanism, reagent needle mechanism is used for sucking reagent from reagent carrier mechanism and mixing the sample sucked by sample needle mechanism, detection mechanism is used for detecting the mixed solution of reagent and sample. With the implementation, the interface of blood plasma and blood cell is detected by sensing mechanism, and the needle height of sample needle and sample suction speed can be quickly controlled to improve the analysis efficiency of sample. In some embodiments, the sensing mechanism includes a vision device that identifies the interface of blood plasma and blood cells.

[0143] On the basis of the fourth embodiment, the drive mechanism in some embodiments can be a two-dimensional or three-dimensional drive mechanism to drive the sample needle to move in a two-dimensional or three-dimensional space. The reagent needle mechanism in some embodiments includes a reagent needle that moves in a two-dimensional or three-dimensional space under the drive of a two-dimensional or three-dimensional drive mechanism.

[0144] On the basis of the fourth embodiment, the detection mechanism in some embodiments can include a reaction device and a light measurement device. The reaction device has at least one placement position for placing a reaction cup and incubating a reaction solution in the reaction cup. For example, the reaction device can be a reaction disc arranged in a disc structure, having one or more placement positions for placing reaction cups, and the reaction disc can rotate and drive the reaction cups in the placement positions to rotate, for scheduling the reaction cups in the reaction disc and incubating the reaction solution in the reaction cups. The light measurement device is used for light measurement on the incubated reaction solution, to obtain reaction data of the sample. For example, the light measurement device detects the luminescence intensity of the to-be-measured reaction solution, and calculates the concentration of the to-be-measured component in the sample through a calibration curve.

[0145] On the basis of the fourth embodiment, the detection mechanism in some embodiments is a coagulation analyzer, which can suck the venous blood in the blood collection tube 10 and perform coagulation analysis.

[0146] The embodiments of the utility model are described in detail above in combination with the drawings, but the utility model is not limited to the above-mentioned embodiments, and various changes can be made within the knowledge range possessed by the ordinary skilled in the art without departing from the purpose of the utility model. In addition, the embodiments of the utility model and the features in the embodiments can be combined with each other without conflict.

Claims

1. A blood collection tube, characterized in that, Includes outer tube, inner tube, and support structure; The outer tube has a second inner cavity that is open at one end; The inner tube is housed in the second inner cavity. The inner tube includes a first receiving portion, which includes a first bottom and a first side portion connected to the first bottom. The first bottom and the first side portion together form a first inner cavity for receiving a sample and open at one end. The opening of the first inner cavity faces the opening of the second inner cavity. There is a gap between the first side portion and the outer tube. The outer tube supports the inner tube through the support portion so that there is a set distance between the first bottom and the tail end of the outer tube. Within the axial extension range of the first side portion, the inner diameter of the first receiving portion is basically consistent.

2. The blood collection tube according to claim 1, characterized in that, The air pressure in the gap between the first side and the outer tube is less than atmospheric pressure.

3. The blood collection tube according to claim 2, characterized in that, The air pressure in the gap is less than the air pressure in the first inner cavity.

4. A blood collection tube, characterized in that, Includes outer tube, inner tube, and support structure; The outer tube has a second inner cavity that is open at one end; The inner tube is housed in the second inner cavity. The inner tube includes a first receiving portion, which includes a first bottom and a first side portion connected to the first bottom. The first bottom and the first side portion together form a first inner cavity for receiving a sample and open at one end. The opening of the first inner cavity faces the opening of the second inner cavity. There is a gap between the first side portion and the outer tube. The outer tube supports the inner tube through the support portion so that there is a set distance between the first bottom and the tail end of the outer tube. Within the axial extension range of the first side portion, and along the direction from the end of the second inner cavity with an opening to the tail end of the outer tube, the inner diameter of the first receiving portion gradually decreases.

5. The blood collection tube according to claim 4, characterized in that, The air pressure in the gap between the first side and the outer tube is less than atmospheric pressure.

6. The blood collection tube according to claim 5, characterized in that, The air pressure in the gap is less than the air pressure in the first inner cavity.

7. A blood collection tube, characterized in that, Includes outer tube, inner tube, and support structure; The outer tube has a second inner cavity that is open at one end; The inner tube is housed in the second inner cavity. The inner tube includes a first receiving portion, which includes a first bottom and a first side portion connected to the first bottom. The first bottom and the first side portion together form a first inner cavity for receiving a sample and open at one end. The opening of the first inner cavity faces the opening of the second inner cavity. The outer tube supports the inner tube through the support portion so that there is a set distance between the first bottom and the tail end of the outer tube. There is a gap between the first side portion and the outer tube, and the air pressure in the gap is less than atmospheric pressure.

8. The blood collection tube according to claim 7, characterized in that, The air pressure in the gap is less than the air pressure in the first inner cavity.

9. The blood collection tube according to any one of claims 1 to 8, characterized in that, The first receiving portion is press-fitted with the outer tube at the end of the first inner cavity that has an opening.

10. The blood collection tube according to claim 9, characterized in that, The first receiving portion further includes an annular flange, which is disposed on the outer surface of the first side portion to achieve an interference fit between the first receiving portion and the outer tube.

11. The blood collection tube according to any one of claims 1 to 8, characterized in that, One end of the support is connected to the first bottom of the first receiving part, and the other end extends toward the tail end of the outer tube and abuts against the outer tube.

12. The blood collection tube according to any one of claims 1 to 8, characterized in that, The outer tube includes a second receiving portion, the second receiving portion including a second bottom and a second side portion connected to the second bottom, the second bottom and the second side portion together forming the second inner cavity; The second bottom has an inner surface with an opening facing the second inner cavity and an outer surface with an opening away from the opening. The axial distance between the closest point of the inner surface to the outer surface and the farthest point of the outer surface from the inner surface is equal to the set distance. The second bottom is configured as the support portion. The first bottom abuts against at least the closest point of the inner surface of the second bottom.

13. The blood collection tube according to any one of claims 1 to 8, characterized in that, The inner tube is made of a first material, and the outer tube is made of a second material, wherein the first material and the second material are different.

14. The blood collection tube according to claim 13, characterized in that, The first material is polypropylene, and the second material is polyethylene terephthalate.

15. The blood collection tube according to any one of claims 1 to 8, characterized in that, The wall thickness of the first side is basically the same.

16. The blood collection tube according to any one of claims 1 to 8, characterized in that, Within the axial extension range of the first side portion, the inner diameter of the first receiving portion is greater than or equal to 6 mm and less than or equal to 7.5 mm; And / or, the outer diameter of the outer tube is greater than or equal to 12 mm and less than or equal to 13 mm.

17. The blood collection tube according to any one of claims 1 to 8, characterized in that, Within the axial extension range of the first side portion, the ratio of the inner diameter of the first receiving portion to the outer diameter of the outer tube is greater than or equal to 0.5 and less than or equal to 0.

63.

18. The blood collection tube according to any one of claims 1 to 8, characterized in that, The set distance is greater than or equal to 10mm.

19. The blood collection tube according to any one of claims 1 to 8, characterized in that, The ratio of the length of the outer tube to the length of the first receiving part is greater than or equal to 1.3 and less than or equal to 2.

20. The blood collection tube according to any one of claims 1 to 8, characterized in that, The volume of the first inner cavity is no more than 2.5 ml.

21. The blood collection tube according to any one of claims 1 to 8, characterized in that, The outer tube includes a second receiving portion, which includes a second bottom and a second side portion connected to the second bottom. The second bottom and the second side portion together form the second inner cavity, wherein the inner diameter of the second receiving portion is substantially the same within the axial extension range of the second side portion.

22. A sample analysis system, characterized in that, include: A sampling needle mechanism includes a sampling needle and a driving mechanism, wherein the sampling needle is mounted on the driving mechanism, and the driving mechanism is used to control the sampling needle to draw samples from the blood collection tube according to any one of claims 1 to 21; The sensing mechanism is used to detect the interface position between plasma and blood cells in the blood collection tube; The controller is used to control the insertion height and sampling speed of the sampling needle based on the detection signal of the sensing mechanism; A reagent needle mechanism is used to draw reagents from a reagent carrier and mix the drawn reagents with the sample drawn by the sampling needle mechanism to form a mixed solution of the reagents and the sample. A testing facility for testing the mixed solution.

23. The sample analysis system according to claim 22, characterized in that, The testing device is a coagulation analyzer.

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