Intracranial nicking balloon drug perfusion catheter

Abstract

The utility model relates to the technical field of vascular intervention, in particular to an intracranial nicking balloon drug perfusion catheter which comprises a catheter far-end check valve, a nicking balloon, a drug perfusion hole, a balloon filling connector, a drug perfusion catheter body and a drug perfusion catheter opening. A balloon filling interface and a drug perfusion catheter port are arranged at the near end of the catheter, and a catheter far end check valve is arranged in an opening at the far end of the catheter. During actual operation, the nicking balloon and the common intracranial balloon respectively reach the far end and the near end of a target blood vessel, and the nicking balloon is used for pre-expanding the target blood vessel area and then relieving pressure; and the common intracranial balloon is filled for near-end blood flow plugging. The medicine enters the target blood vessel area from the medicine filling hole through the nicking balloon catheter tube cavity, the nicking balloon is filled again, medicine particles are embedded in plaque dents and plaque tiny cracks generated by pre-expansion, and therefore the medicine particles are retained in plaques. According to the intracranial drug balloon, the dilemma that an existing intracranial drug balloon cannot achieve rapid in-place and high in-place of intracranial blood vessels is thoroughly changed.

Description

TECHNICAL FIELD

[0001] The utility model relates to a blood vessel intervention technical field, concretely relates to a intracranial score balloon medicine perfusion catheter. BACKGROUND

[0002] In recent years, drug balloons have shown their advantages in the treatment of restenosis in stents and microvessel stenosis. In the treatment of restenosis in stents, drug balloons have almost become the only choice. With the increasing rejection of people to the implantation of foreign objects, the concept of "intervention without implantation" has been deeply rooted in people's minds. Related research has also confirmed that drug balloons are effective in the treatment of certain blood vessel problems, and the research and exploration of drug balloons have become increasingly in-depth in recent years.

[0003] At present, there is no intracranial drug balloon on the market. The intracranial drug balloons used in clinical trials are almost derived from the design concept of intracardiac intervention drug balloons. In intracardiac intervention, the blood vessel channel is relatively short and the related blood vessels are relatively straight, so there is no obvious problem of difficulty in transporting or positioning the drug balloon designed for intracardiac intervention. At the same time, the design of intracardiac intervention drug balloons emphasizes the common carrier properties of the balloon and the drug (the balloon wall is wrapped with the drug, and the balloon and the drug are the common carrier), so that the drug balloon emphasizes its rapid arrival at the target blood vessel area during use to reduce the loss of the drug during the transmission process. Therefore, the current intracardiac intervention drug balloon is abnormally hard and the diameter of the balloon drug carrier is large.

[0004] Neurointervention learns from the successful example of intracardiac intervention, and tries to change the strength or drug layer of the drug balloon to solve the related defects in the design concept of intracardiac intervention drug balloons. It is undeniable that these design optimizations of intracranial drug balloons have indeed changed the blood vessel positioning of intracranial drug balloons; however, the softness and high positioning of the intracranial balloon cannot be compared with the current intracranial drug balloon, and the distal blood vessel lesions of the intracranial blood vessels are not uncommon. In addition, the intracranial arterial blood vessels have their own particularity: the intracranial blood vessel lumen is tortuous, the intracranial arterial blood vessel wall is thinner, and the blood vessel lumen is thinner. The drug balloon lacking in flexibility is not easy to pass through the tortuous blood vessels, and cannot achieve rapid arrival at the target blood vessel site. The friction between the drug balloon and the blood vessel wall can easily cause the intracranial artery to bleed, and the design problem of the drug balloon carrier (the balloon wall is wrapped with the drug, and the balloon and the drug are the common carrier) makes the overall diameter of the drug balloon carrier larger, which cannot pass through the small intracranial blood vessel lumen.

[0005] Therefore, the intracranial drug balloon designed based on the concept of intracardiac intervention cannot meet the development and needs of neurointervention, and it is necessary to design a new drug balloon carrier to adapt to the progress and development of neurointervention. UTILITY MODEL CONTENT

[0006] The utility model discloses a purpose lies in providing a kind of intracranial score balloon medicine perfusion catheter, to solve the technical problems of the current intracranial drug balloon in intracranial vascular intervention surgery vessel difficult and unable to realize the high position of blood vessel.

[0007] To achieve the above object, the utility model provides an intracranial score balloon medicine perfusion catheter, including catheter distal end stop valve, score balloon, balloon mark point, medicine perfusion hole, balloon filling interface, medicine perfusion pipe body and medicine perfusion catheter mouth, the balloon filling interface and the medicine perfusion catheter mouth set the proximal end of the medicine perfusion pipe body, the catheter distal end stop valve is arranged in the opening of the medicine perfusion pipe body distal end, the score balloon and the medicine perfusion hole are sequentially arranged along the distal end of the medicine perfusion pipe body to the proximal end direction, the score balloon is arranged at the distal pipe wall outside of the medicine perfusion pipe body, the score balloon is connected with the balloon filling interface through pipe wall microchannel, the balloon mark point is arranged at the long axis of score balloon two sides, the medicine perfusion hole is distributed in the balloon mark point close to medicine perfusion catheter mouth side, the medicine perfusion hole is symmetrically distributed and is distributed in catheter two sides, and the medicine perfusion flow direction is from the proximal end of the medicine perfusion pipe body to the distal end.

[0008] Wherein, the catheter distal end stop valve is prepared using elastic plastic material, is set to annular closed loop in non-extrusion state, and can accommodate micro guide wire to be inserted through in extrusion state.

[0009] Wherein, the score balloon is set to 1.5mm / 2.0mm / 2.5mm in ball diameter size specification, and the different lengths of corresponding balloon long axis are set to 1.0cm / 1.5cm / 2.0cm, a plurality of score particles are evenly arranged on the outside of the score balloon, and the score particles are set in the appearance as conical convex.

[0010] Wherein, the lumen outer diameter of the medicine perfusion pipe body is set to 1.7F in size, and is set to 160cm in length.

[0011] In actual operation, score balloon and ordinary intracranial balloon reach target blood vessel distal and proximal ends respectively, score balloon pre-dilates target blood vessel area and depressurizes, and ordinary intracranial balloon is inflated to block proximal blood flow. Medicine enters target blood vessel area through score balloon catheter lumen and medicine perfusion hole, score balloon is inflated again, and medicine particles are embedded in plaque indentation and plaque microcracks generated by pre-dilation, so that medicine particles are retained in plaque. The utility model will completely change the current intracranial drug balloon and realize the difficulty of rapid intracranial vascular positioning and high positioning. BRIEF DESCRIPTION OF DRAWINGS

[0012] In order to more clearly illustrate the technical solutions of the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiments or the prior art description. Obviously, the drawings described in the following are only some embodiments of the present application, and for those skilled in the art, other drawings can also be obtained from these drawings without creative labor.

[0013] Figure 1 is a structural schematic diagram of an intracranial scoring balloon drug perfusion catheter of the present application.

[0014] Figure 2 is a cross-sectional structural schematic diagram of a scoring balloon of the present application.

[0015] Figure 3 is a process schematic diagram of introducing an intracranial target blood vessel using a neural micro guide wire of the present application.

[0016] Figure 4 is a schematic diagram of using an intracranial scoring balloon drug perfusion catheter of the present application in cooperation with a common intracranial balloon.

[0017] Figure 5 is a drug flow direction schematic diagram of intracranial scoring balloon drug perfusion catheter of the present application.

[0018] 1-catheter distal end stop valve, 2-scoring balloon, 3-balloon marker point, 4-drug perfusion hole, 5-balloon filling interface, 6-drug perfusion tube, 7-drug perfusion catheter port, 8-scoring particles, 9-micro guide wire, 10-common intracranial balloon. DETAILED DESCRIPTION

[0019] The embodiments of the present application will be described in detail below, and examples of the embodiments are shown in the drawings, wherein the same or similar reference signs represent the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary and are intended to explain the present application, and cannot be understood as a limitation of the present application.

[0020] Please refer to Figures 1 to 5The utility model provides a kind of intracranial score balloon drug perfusion catheter, including catheter distal end stop valve 1, score balloon 2, balloon marker point 3, drug perfusion hole 4, balloon filling interface 5, drug perfusion pipe body 6 and drug perfusion catheter mouth 7, the balloon filling interface 5 and the drug perfusion catheter mouth 7 setting the proximal end of the drug perfusion pipe body 6, the catheter distal end stop valve 1 is arranged in the opening of the drug perfusion pipe body 6 distal end, the score balloon 2 and the drug perfusion hole 4 are sequentially arranged along the distal end of the drug perfusion pipe body 6 to proximal end direction, the score balloon 2 is arranged at the outer side of the distal tube wall of the drug perfusion pipe body 6, the score balloon 2 is connected with the balloon filling interface 5 by tube wall microchannel, the balloon marker point 3 is arranged at the long axis both sides of score balloon 2, the drug perfusion hole 4 is arranged at the proximal tube wall both sides of balloon marker point 3, and it is set as double holes of opposite sides, and the drug perfusion flow direction is from the proximal end to the distal end of the drug perfusion pipe body 6.

[0021] The catheter distal end stop valve 1 is made of elastic plastic material, and the stop valve can allow the micro guide wire 9 to pass through and prevent blood flow and drug from passing through after the micro guide wire 9 is withdrawn.

[0022] The score balloon 2 is provided in sizes of 1.5mm, 2.0mm and 2.5mm to adapt to the intracranial blood vessel diameter, and different lengths (1.0cm, 1.5cm, 2.0cm) of the score balloon of corresponding size are provided to cover the plaque in the blood vessel, a plurality of groups of score particles 8 are uniformly arranged on the outer side of the score balloon 2, the score particles 8 are arranged in the form of conical protrusions, and the score balloon 2 is made of a material rich in elasticity such as polyurethane.

[0023] The score particles 8 are symmetrically distributed in the working state of the balloon, and there are not less than four score particles in the cross section of the smallest balloon size (1.5mm balloon size), and the score balloon 2 has developing mark points at both ends of the long axis direction.

[0024] The drug perfusion holes 4 are distributed on the side close to the drug perfusion catheter mouth 7 of the balloon marker point 3, the drug perfusion double holes are symmetrically distributed and distributed on both sides of the catheter, and the perfusion drug can be stably filled in the blood vessel through the drug perfusion double holes.

[0025] The outer diameter of the lumen of the drug perfusion pipe body 6 is set to 1.7F, and the length is set to 160cm, so as to realize the rapid positioning of the drug perfusion catheter in the intracranial artery and the high positioning of the distal end of the intracranial artery.

[0026] In the embodiment, the proximal end of the drug perfusion tube body 6 is the operation area of the medical staff, the distal end of the drug perfusion tube body 6 enters the intracranial blood vessel for operation implementation, the catheter distal end stop valve 1, the notched balloon 2 and the drug perfusion hole 4 are all located at the distal end, in actual operation, the micro guide wire 9 is inserted through the catheter distal end stop valve 1 to guide the intracranial notched balloon drug perfusion catheter to reach the target blood vessel, and another micro guide wire guides the intracranial ordinary balloon 10 to the proximal end of the target blood vessel area; the notched balloon 2 is pre-dilated through the balloon inflation interface 5, the micro guide wire 9 is withdrawn after the pressure of the notched balloon 2, and the catheter distal end stop valve 1 is in the working state. The catheter distal end stop valve 1 is made of elastic memory material, the micro guide wire 9 can be inserted through the catheter distal end stop valve 1, but the catheter distal end stop valve 1 restores to the original state and remains closed after the micro guide wire 9 is withdrawn, and the perfusion drug cannot pass through the catheter distal end stop valve 1.

[0027] Further, the notched particles 8 outside the notched balloon 2 generate a plurality of plaque indentations and micro cracks in the vascular plaque when the notched balloon 2 is pre-dilated, the ordinary intracranial balloon 10 is inflated in the target blood vessel after the pressure of the notched balloon 2 is released, and when the ordinary intracranial balloon 10 is inflated and completely stops bleeding, the drug slowly enters the target blood vessel area through the lumen of the drug perfusion tube body 6 and from the drug perfusion hole 4, the drug is retained in the front part of the ordinary intracranial balloon 10 and the vascular gap around the notched balloon 2, and the vascular plaque indentations and micro cracks generated by the pre-dilation of the notched balloon 2, and the notched balloon 2 is slowly inflated again, and the perfusion drug particles are firmly impacted in the plaque indentations and micro cracks, so as to achieve the purpose of long-term local retention of the drug in the plaque.

[0028] The above only discloses a preferred embodiment of the utility model, and of course cannot limit the scope of the utility model, and those skilled in the art can understand that all or part of the processes of the above embodiment are implemented, and equivalent changes made according to the utility model claims still belong to the range covered by the utility model.

Claims

1. An intracranial scoring balloon drug perfusion catheter, characterized in that, It comprises a catheter distal end stop valve, a scoring balloon, a balloon marker point, a drug perfusion hole, a balloon inflation interface, a drug perfusion tube and a drug perfusion catheter port, the balloon inflation interface and the drug perfusion catheter port are arranged at the proximal end of the drug perfusion tube, the catheter distal end stop valve is arranged in the opening at the distal end of the drug perfusion tube, the scoring balloon and the drug perfusion hole are arranged in sequence along the distal end to the proximal end of the drug perfusion tube, the scoring balloon is arranged outside the distal tube wall of the drug perfusion tube, the scoring balloon is connected with the balloon inflation interface through the tube wall microchannel, the balloon marker point is arranged on both sides of the long axis of the scoring balloon, the drug perfusion holes are distributed on the side of the balloon marker point close to the drug perfusion catheter port, the drug perfusion holes are symmetrically distributed and distributed on both sides of the catheter, and the drug perfusion flow direction is from the proximal end to the distal end of the drug perfusion tube.

2. The intracranial scoring balloon drug perfusion catheter of claim 1, characterized in that, The catheter distal end stop valve is made of elastic plastic material and is arranged in a ring-shaped closed loop in a non-extrusion state and can accommodate a micro guide wire inserted through in an extrusion state.

3. The intracranial scoring balloon drug perfusion catheter of claim 2, characterized in that, The scoring balloon has a ball diameter size of 1.5mm / 2.0mm / 2.5mm and a corresponding balloon long axis length of 1.0cm / 1.5cm / 2.0cm, and a plurality of scoring particles are uniformly arranged on the outside of the scoring balloon, and the scoring particles are arranged in a conical protruding shape.

4. The intracranial scoring balloon drug perfusion catheter of claim 3, characterized in that, The lumen outer diameter of the drug perfusion tube is 1.7F and the length is 160cm.

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