Tissue crushing device for gene detection

Abstract

The utility model discloses a tissue smashing device for gene detection, which belongs to the technical field of gene detection and comprises a box body, stand columns are arranged at four corners of the bottom end of the box body, a conveying cylinder is arranged above the top end of the box body, a material guide frame is arranged on the side wall of the conveying cylinder, and the bottom end of the material guide frame extends into the box body. A feeding frame is fixedly installed on the side wall of the upper portion of the conveying cylinder, and a conveying assembly is arranged in the conveying cylinder. A smashing assembly is arranged in the box body, a water storage tank is fixedly installed on one side of the box body, a water inlet pipe is arranged at the top end of the water storage tank, a spraying assembly is arranged between the water storage tank and the box body, a discharging frame is arranged on the inner wall of the bottom end of the box body, and the bottom end of the discharging frame penetrates through the box body. Through the arrangement of the crushing assembly and the cooperation of the two crushing rollers, the multi-stage sample crushing effect is achieved, the sample crushing effect is improved, subsequent gene extraction is facilitated, and the crushing efficiency of the equipment is kept.

Description

TECHNICAL FIELD

[0001] The utility model relates to gene detection technical field more specifically, relate to a kind of tissue pulverizing device for gene detection. BACKGROUND

[0002] Gene is the basic unit of inheritance, carries DNA or RNA sequence of genetic information, and transmits genetic information to the next generation by replication, gene detection is the technology of detecting DNA through blood, other body fluids or cells, detects DNA molecule information in the cells of the person to be tested by specific equipment, analyzes the gene type and gene defect contained in it and whether the expression function is normal, one of the steps in gene detection needs to be pulverized by pulverizing device, to facilitate subsequent extraction of gene.

[0003] Patent No. 202321355397.7 discloses a kind of tissue pulverizing device for gene detection, including outer box, hopper, motor two, filter cartridge, pulverizing brush device and cleaning device, the hopper is located at the upper end of outer box, the motor two is located at the bottom of outer box, the filter cartridge is located at the power output end of motor two and rotates in the inside of outer box, the pulverizing brush device is located in the inside of filter cartridge, the cleaning device is located on the inner wall of outer box and closely adheres to the outer wall of filter cartridge. The utility model can reverse flush the filter cartridge, not only can guarantee the efficiency of filtration, but also can clean the filter cartridge for subsequent gene detection.

[0004] For the above-mentioned related technology, the device is pulverized by the sample through the pulverizing teeth, and then the filter cartridge is cleaned by the setting of the pulverizing brush device and the cleaning device, which helps to avoid the phenomenon of filter cartridge blockage, and facilitates subsequent collection of pulverized samples, but the pulverizing teeth are located in the middle of the filter cartridge, the sleeve two and the guide rod two are arranged above the bottom of the filter cartridge, which facilitates the cleaning of the filter cartridge, so that the pulverizing teeth have a certain distance from the bottom of the filter cartridge, and the sample falling to the bottom of the filter cartridge may not be completely pulverized, thereby affecting the subsequent extraction of gene by the staff and reducing the pulverizing effect of the device. UTILITY MODEL CONTENTS

[0005] In order to solve the above problems, the utility model provides a kind of tissue pulverizing device for gene detection, adopt the following technical solutions:

[0006] A kind of tissue pulverizing device for gene detection, including box, the box bottom end four corners are each equipped with stand, the box top is equipped with conveying cylinder above, the conveying cylinder side wall is equipped with guide frame, the guide frame bottom end extends into the box, the conveying cylinder upper portion side wall is fixedly installed with feed frame, the conveying cylinder is equipped with conveying assembly;

[0007] The box is internally provided with a crushing assembly, a water storage tank is fixedly installed on one side of the box, a water inlet pipe is arranged at the top end of the water storage tank, a spraying assembly is arranged between the water storage tank and the box, a discharging frame is arranged on the inner wall of the bottom end of the box, the bottom end of the discharging frame penetrates the box, mounting blocks are fixedly installed between the inner sides of two upright columns on the same side, and a collecting frame is arranged between the two mounting blocks.

[0008] Through the above technical scheme, when the device is in use, the worker places the collecting frame below the box, then the worker puts the sample into the feeding frame, the sample enters the conveying cylinder through the feeding frame, then the sample moves towards the guide frame under the action of the conveying assembly, then the sample enters the box through the guide frame, the box is internally provided with a crushing assembly, which can crush the sample, the crushed sample falls into the collecting frame through the discharging frame, which is convenient for the worker to collect and use later, when it is necessary to clean the crushing assembly and the box, the water source in the water storage tank is sprayed to the surface of the crushing assembly through the spraying assembly, which can clean the crushing assembly, and the waste water falls into the collecting frame through the discharging frame, which can collect the waste water.

[0009] Further, the conveying assembly comprises a second rotating rod rotatably installed in the conveying cylinder, a spiral blade is fixedly sleeved on the side wall of the second rotating rod, an installation box is fixedly installed on one side of the conveying cylinder, a second speed reducer motor is fixedly installed in the installation box, one end of the second rotating rod penetrates the conveying cylinder and extends into the installation box, and the other end of the second rotating rod penetrating the installation box is fixedly connected with the output shaft end of the second speed reducer motor.

[0010] Through the above technical scheme, when the sample is put into the conveying cylinder, the second rotating rod is driven to rotate by the second speed reducer motor, the spiral blade is driven to rotate by the second rotating rod, the sample is conveyed towards the guide frame by the rotation of the spiral blade, the sample enters the box through the guide frame, which can realize the feeding function, and the spiral blade not only conveys the sample, but also stirs and mixes the sample, which facilitates uniform crushing of the sample later.

[0011] Further, the crushing assembly comprises two groups of first rotating rods arranged in the box, the first rotating rods in the same group are two and symmetrically arranged in the box, a crushing roller is fixedly sleeved on the side wall of each first rotating rod, one end of each first rotating rod away from the water storage tank penetrates the box, a drive gear is sleeved on the side wall of the end of each first rotating rod penetrating the box, the two drive gears in the same group are in meshing engagement, a support rod is rotatably installed on the side of the box away from the water storage tank, a transmission gear is fixedly sleeved on the side wall of the support rod, a first speed reducer motor is fixedly installed on the side of the box away from the water storage tank, and the output shaft of the first speed reducer motor is fixedly connected with the end of the support rod opposite to the transmission gear. The two drive gears are in meshing engagement with the transmission gear.

[0012] By adopting the above technical scheme, when the sample enters the inside of the box body, the first speed reducer drives the support rod to rotate, the support rod drives the transmission gear to rotate, the transmission gear drives the connected driving gear to rotate, the multiple driving gears are cooperatively driven to rotate the first rotating rod in the same group, the first rotating rod drives the crushing roller in the same group to rotate, thereby playing a role of crushing the sample, and the multiple crushing rollers are cooperatively used to play a role of multi-stage crushing the sample, thereby being beneficial to improving the crushing effect of the sample.

[0013] Further, the spraying assembly comprises a water pump arranged in the water storage tank, the water storage tank is provided with a second double connector at the top end, the bottom end of the second double connector penetrates into the water storage tank, a connecting pipe is connected between the opposite ends of the water pump and the second double connector, first double connectors are fixedly installed on both sides of the box body, the branch pipes of the two first double connectors both penetrate into the box body, the branch pipes of the two first double connectors are both provided with main pipes, the side walls of the main pipes are both provided with a plurality of spray heads arranged in a linear array, and conduits are arranged between the two first double connectors and the second double connector.

[0014] By adopting the above technical scheme, the water source in the water storage tank is introduced into the connecting pipe through the operation of the water pump, then is branched into the two conduits through the second double connector, then is branched into the main pipes through the first double connectors, and then the water source is sprayed onto the crushing roller through the spray heads, thereby playing a role of cleaning the crushing roller, being beneficial to maintaining the cleanliness of the inside of the box body and the crushing roller, and being convenient for subsequent reuse.

[0015] Further, the opposite sides of the two mounting blocks are both provided with sliding grooves, sliding blocks are slidingly installed in the two sliding grooves, and the opposite sides of the two sliding blocks are both fixedly connected to the opposite side of the collecting frame.

[0016] By adopting the above technical scheme, the collecting frame is fixedly connected to the sliding grooves formed in the opposite sides of the two mounting blocks through the sliding blocks, which is convenient for the subsequent disassembly of the collecting frame by the staff to collect the crushed sample, and the collecting frame is provided with a drain pipe on one side, which is convenient for subsequent drainage of wastewater for cleaning the box body.

[0017] Further, rubber sleeves are fixedly sleeved on the side walls of the two sliding blocks.

[0018] By adopting the above technical scheme, the rubber sleeves arranged on the side walls of the sliding blocks are beneficial to increasing the friction between the sliding blocks and the sliding grooves on the same side, and are beneficial to maintaining the stability of the installation of the collecting frame.

[0019] Further, a counterweight is arranged at the bottom of the side of the box body away from the water storage tank, and a supporting block is arranged between the box body and the conveying cylinder.

[0020] By adopting the technical scheme, the counterweight is arranged on one side of the box body, so that the box body is balanced, and the stability of the box body in use is maintained.

[0021] In summary, the utility model has the following beneficial technical effects:

[0022] (1) In the utility model, the two crushing rollers are matched to play a multi-stage crushing sample role, so that the crushing effect of the sample is improved, the gene is conveniently extracted, and the crushing efficiency of the equipment is maintained.

[0023] (2) In the utility model, the water source in the water storage tank is sprayed to the same side crushing roller through the spray head by the water pump, so that the crushing roller and the box body are cleaned, and the cleanliness of the internal structure of the box body is maintained.

[0024] (3) In the utility model, the second rotating rod is driven to rotate by the second speed reducer motor, the spiral blade is driven to rotate by the second rotating rod, the sample is conveyed, the sample is mixed, and the sample is uniformly crushed. BRIEF DESCRIPTION OF DRAWINGS

[0025] Figure 1 It is a structure schematic view of the first perspective of the utility model;

[0026] Figure 2 It is an enlarged view of A in the utility model; Figure 1

[0027] Figure 3 It is a structure schematic view of the second perspective of the utility model;

[0028] Figure 4 It is a sectional view of the utility model;

[0029] Figure 5 It is an enlarged view of B in the utility model; Figure 4

[0030] Figure 6 It is an explosion view of the crushing assembly in the utility model.

[0031] Explanation of reference numerals in the drawing:

[0032] ​​1, box; 2, water storage tank; 3, conduit; 4, first double connector; 5, guide frame; 6, conveying cylinder; 7, feeding frame; 8, mounting box; 9, drive gear; 10, first rotating rod; 11, first speed reducer motor; 12, mounting block; 13, sliding block; 14, collection frame; 15, transmission gear; 16, support rod; 17, second double connector; 18, chute; 19, spiral blade; 20, second rotating rod; 21, second speed reducer motor; 22, main pipe; 23, nozzle; 24, crushing roller; 25, connecting pipe; 26, water pump; 27, discharging frame. DETAILED DESCRIPTION

[0033] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0034] In the description of the present application, it should be noted that the terms "upper", "lower", "inner", "outer", "top / bottom end" and the like indicate the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the present application. In addition, the terms "first", "second" are only for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0035] In the description of the present application, it should be noted that unless otherwise explicitly specified and limited, the terms "mounting", "provided with", "sleeved / connected", "connected" and the like should be broadly understood, for example, "connected" can be fixedly connected, or can be detachably connected, or integrally connected; can be mechanically connected, or can be electrically connected; can be directly connected, or can be indirectly connected through an intermediate medium; can be the communication inside two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0036] The following will be described in detail with reference to the accompanying drawings Figures 1-6 The present application will be further described in detail.

[0037] Please refer to Figures 1-6The utility model provides a kind of tissue pulverizing device for gene detection, including box 1, box 1 bottom end four corners are equipped with stand, box 1 top is equipped with conveying cylinder 6 above, conveying cylinder 6 side wall is equipped with guide frame 5, guide frame 5 bottom end extends into box 1, conveying cylinder 6 upper side wall is fixedly installed with feed frame 7, box 1 bottom end inner wall is equipped with blanking frame 27, blanking frame 27 bottom end penetrates box 1, between the inboard of same side two stands, two mounting blocks 12 are fixedly installed, collecting frame 14 is equipped between two mounting blocks 12, two mounting blocks 12 opposite side are all set with sliding slot 18, two sliding slots 18 are all slidably installed with sliding block 13, the opposite side of two sliding blocks 13 is all fixedly connected with the opposite side of collecting frame 14, the side of collecting frame 14 is equipped with handle, the side of collecting frame 14 close to handle is equipped with drain pipe, and the side wall of two sliding blocks 13 is all fixedly covered with rubber sleeve.

[0038] When the device is in use, the worker places the collecting frame 14 below the box 1, and the collecting frame 14 is fixedly engaged with the sliding slots 18 on the opposite sides of the two mounting blocks 12 through the sliding blocks 13, which facilitates the worker to disassemble the collecting frame 14 for collecting the pulverized samples later, and the side of the collecting frame 14 is provided with a drain pipe, which facilitates the subsequent discharge of wastewater for cleaning the box 1, and the side wall of the sliding block 13 is provided with a rubber sleeve, which is helpful to increase the friction between the sliding block 13 and the sliding slot 18 on the same side and to maintain the stability of the installation of the collecting frame 14.

[0039] The conveying cylinder 6 is provided with a conveying assembly, which includes a second rotating rod 20 rotatably installed in the conveying cylinder 6, and a spiral blade 19 fixedly sleeved on the side wall of the second rotating rod 20, and the conveying cylinder 6 is fixedly installed with a mounting box 8 on one side, and the mounting box 8 is fixedly installed with a second speed reducer 21 inside, and one end of the second rotating rod 20 penetrates the conveying cylinder 6 and extends into the mounting box 8, and the end of the second rotating rod 20 penetrating the mounting box 8 is fixedly connected with the output shaft end of the second speed reducer 21, the worker puts the sample into the feed frame 7, and the sample enters the conveying cylinder 6 through the feed frame 7, then the second rotating rod 20 is driven to rotate by the second speed reducer 21, the spiral blade 19 is driven to rotate by the second rotating rod 20, and the sample is conveyed towards the guide frame 5 by the rotation of the spiral blade 19, and the sample enters the box 1 through the guide frame 5, which can play the role of feeding, and the spiral blade 19 not only plays the role of conveying the sample, but also plays the role of stirring and mixing the sample, which facilitates the uniform pulverization of the sample later.

[0040] The box 1 is provided with a crushing assembly, the crushing assembly comprises two groups of first rotating rods 10 arranged in the box 1, the same group of first rotating rods 10 is two and is symmetrically distributed in the box 1, the side wall of the first rotating rod 10 is fixedly sleeved with a crushing roller 24, the end of the first rotating rod 10 away from the water storage tank 2 penetrates the box 1, and the side wall of the end of the first rotating rod 10 penetrating the box 1 is sleeved with a driving gear 9, the two driving gears 9 of the same group are in meshing, the box 1 is rotatably installed with a supporting rod 16 on the side away from the water storage tank 2, the side wall of the supporting rod 16 is fixedly sleeved with a transmission gear 15, the box 1 is fixedly installed with a first speed reducer 11 on the side away from the water storage tank 2, and the output shaft of the first speed reducer 11 is fixedly connected with the end of the supporting rod 16 opposite to the side wall, wherein the two driving gears 9 are in meshing with the transmission gear 15, when the sample enters the inside of the box 1, the supporting rod 16 is driven to rotate by the first speed reducer 11, the supporting rod 16 drives the transmission gear 15 to rotate, the transmission gear 15 drives the driving gear 9 connected therewith to rotate, the first rotating rod 10 of the same group is driven to rotate through the cooperation of the plurality of driving gears 9, the first rotating rod 10 drives the crushing roller 24 of the same group to rotate, and the sample can be crushed, the sample can be crushed in multiple stages through the cooperation of the plurality of crushing rollers 24, and the crushing effect of the sample is improved.

[0041] The box 1 is rotatably installed with a supporting rod 16 on the side away from the water storage tank 2, the side wall of the supporting rod 16 is fixedly sleeved with a transmission gear 15, the box 1 is fixedly installed with a first speed reducer 11 on the side away from the water storage tank 2, and the output shaft of the first speed reducer 11 is fixedly connected with the end of the supporting rod 16 opposite to the side wall, wherein the two driving gears 9 are in meshing with the transmission gear 15, when the sample enters the inside of the box 1, the supporting rod 16 is driven to rotate by the first speed reducer 11, the supporting rod 16 drives the transmission gear 15 to rotate, the transmission gear 15 drives the driving gear 9 connected therewith to rotate, the first rotating rod 10 of the same group is driven to rotate through the cooperation of the plurality of driving gears 9, the first rotating rod 10 drives the crushing roller 24 of the same group to rotate, and the sample can be crushed, the sample can be crushed in multiple stages through the cooperation of the plurality of crushing rollers 24, and the crushing effect of the sample is improved.

[0042] Through the operation of the water pump 26, the water source in the water storage tank 2 enters the connecting pipe 25, then is shunted to the two pipes 3 through the second double connector 17, then is shunted to the main pipe 22 through the first double connector 4, and then the water source is sprayed on the crushing roller 24 through the spray head 23, so that the crushing roller 24 can be cleaned, the cleanliness of the inside of the box 1 and the crushing roller 24 can be maintained, and the subsequent reuse is facilitated.

[0043] The box 1 is rotatably installed with a supporting rod 16 on the side away from the water storage tank 2, the side wall of the supporting rod 16 is fixedly sleeved with a transmission gear 15, the box 1 is fixedly installed with a first speed reducer 11 on the side away from the water storage tank 2, and the output shaft of the first speed reducer 11 is fixedly connected with the end of the supporting rod 16 opposite to the side wall, wherein the two driving gears 9 are in meshing with the transmission gear 15, when the sample enters the inside of the box 1, the supporting rod 16 is driven to rotate by the first speed reducer 11, the supporting rod 16 drives the transmission gear 15 to rotate, the transmission gear 15 drives the driving gear 9 connected therewith to rotate, the first rotating rod 10 of the same group is driven to rotate through the cooperation of the plurality of driving gears 9, the first rotating rod 10 drives the crushing roller 24 of the same group to rotate, and the sample can be crushed, the sample can be crushed in multiple stages through the cooperation of the plurality of crushing rollers 24, and the crushing effect of the sample is improved.

[0044] The working personnel puts the collecting frame 14 under the box body 1 during use of the device, then the working personnel puts the sample into the feeding frame 7, the sample enters the conveying cylinder 6 through the feeding frame 7, then the sample moves to the direction of the guide frame 5 under the action of the conveying assembly, then the sample enters the box body 1 through the guide frame 5, the box body 1 is provided with a crushing assembly, the crushing assembly can crush the sample, the crushed sample falls into the collecting frame 14 through the discharging frame 27, and the working personnel can conveniently collect and use the sample subsequently; when it is necessary to clean the crushing assembly and the box body 1, the water source in the water storage tank 2 is sprayed to the surface of the crushing assembly through the spraying assembly, the crushing assembly can be cleaned, waste water falls into the collecting frame 14 through the discharging frame 27, and the waste water can be collected.

[0045] The above are preferred embodiments of the utility model, and do not limit the protection scope of the utility model, so that: equivalent changes made according to the structure, shape and principle of the utility model should be covered in the protection scope of the utility model.

Claims

1. A tissue pulverizing device for genetic testing, comprising a box (1), characterized in that: The box (1) bottom end four corners are provided with stand columns, the box (1) top end is provided with a conveying cylinder (6), the conveying cylinder (6) side wall is provided with a material guide frame (5), the material guide frame (5) bottom end extends into the box (1), the conveying cylinder (6) upper portion side wall is fixedly installed with a feeding frame (7), the conveying cylinder (6) is provided with a conveying assembly; The box (1) is provided with a crushing assembly, the box (1) one side is fixedly installed with a water storage tank (2), the water storage tank (2) top end is provided with a water inlet pipe, the water storage tank (2) and the box (1) are provided with a spraying assembly, the box (1) bottom end inner wall is provided with a discharging frame (27), the discharging frame (27) bottom end penetrates the box (1), the same side two stand column inner sides are fixedly installed with mounting blocks (12), and the two mounting blocks (12) are provided with a collecting frame (14).

2. The tissue pulverizing apparatus for genetic testing according to claim 1, wherein: The conveying assembly comprises a second rotating rod (20) rotatably installed in the conveying cylinder (6), the second rotating rod (20) side wall is fixedly sleeved with a spiral blade (19), one side of the conveying cylinder (6) is fixedly installed with a mounting box (8), the mounting box (8) is fixedly installed with a second speed reducer motor (21), one end of the second rotating rod (20) penetrates the conveying cylinder (6) and extends into the mounting box (8), and one end of the second rotating rod (20) penetrating the mounting box (8) is fixedly connected with the second speed reducer motor (21) output shaft end.

3. The tissue pulverizing apparatus for genetic testing according to claim 1, characterized by: The crushing assembly comprises two groups of first rotating rods (10) arranged in the box (1), the first rotating rods (10) in the same group are two and symmetrically distributed in the box (1), the first rotating rod (10) rotating rod side wall is fixedly sleeved with a crushing roller (24), and one end of the first rotating rod (10) away from the water storage tank (2) rotatably penetrates the box (1), and the first rotating rod (10) one end side wall penetrating the box (1) is sleeved with a drive gear (9), the two drive gears (9) in the same group are in meshing engagement, the box (1) side away from the water storage tank (2) is rotatably installed with a supporting rod (16), the supporting rod (16) side wall is fixedly sleeved with a transmission gear (15), the box (1) side away from the water storage tank (2) is fixedly installed with a first speed reducer motor (11), and the first speed reducer motor (11) output shaft is fixedly connected with the one end of the supporting rod (16) opposite to each other, wherein the two drive gears (9) are in meshing engagement with the transmission gear (15).

4. The tissue pulverizing apparatus for genetic testing according to claim 1, wherein: The spraying assembly comprises a water pump (26) arranged in a water storage tank (2), the water storage tank (2) is provided with a second double connector (17) at the top end, the bottom end of the second double connector (17) penetrates into the water storage tank (2), a connecting pipe (25) is connected between the opposite end of the water pump (26) and the second double connector (17), the box (1) is fixedly provided with a first double connector (4) on both sides, the branch pipes of the two first double connectors (4) penetrate into the box (1), the branch pipes of the two first double connectors (4) are provided with a main pipe (22), the side walls of the main pipe (22) are provided with a plurality of spray heads (23) arranged in a straight line, and the two first double connectors (4) and the second double connector (17) are provided with a conduit (3).

5. The tissue pulverizing apparatus for genetic testing according to claim 1, wherein: The opposite sides of the two mounting blocks (12) are provided with sliding grooves (18), the two sliding grooves (18) are slidably provided with sliding blocks (13), the opposite sides of the two sliding blocks (13) are fixedly connected with the opposite sides of the collecting frame (14), one side of the collecting frame (14) is provided with a handle, and one side of the collecting frame (14) close to the handle is provided with a drain pipe.

6. The tissue pulverizing apparatus for genetic testing according to claim 5, wherein: The side walls of the two sliding blocks (13) are fixedly provided with rubber sleeves.

7. The tissue pulverizing apparatus for genetic testing according to claim 1, wherein: The bottom of the side of the box (1) away from the water storage tank (2) is provided with a counterweight, and the box (1) and the conveying cylinder (6) are provided with a supporting block.

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