Freeze-drying tray for a vial with a height limiting device

Abstract

The utility model provides a kind of with high limiting device's penicillin bottle freeze-drying tray, including freeze-drying tray and baffle strip, freeze-drying tray includes bottom plate and four vertical side plates, a group of opposite side plates are equipped with multiple groups of sockets, multiple baffle strips are parallelly installed on freeze-drying tray, the both ends of any baffle strip are respectively inserted in a group of corresponding sockets, and penicillin bottle placing space is formed between adjacent two baffle strips;Socket includes two clamping grooves, when baffle strip is inserted in the upper clamping groove of socket, the height of the top end of baffle strip is consistent with the height of penicillin bottle rubber plug after half-plugging;When baffle strip is inserted in the lower clamping groove of socket, the height of the top end of baffle strip is consistent with the height of penicillin bottle rubber plug when sealing.The utility model can move in socket by baffle strip, and keep different height, can limit half-plugging and full-plugging in penicillin bottle plug cover process, so as to guarantee that penicillin bottle rubber plug plug cover action is uniform, ensure that freeze-drying process is carried out smoothly, reduce the rate of defective products.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical pharmacy technical field, specifically, relate to a kind of penicillin bottle freeze-drying tray with height limiting device. BACKGROUND

[0002] Freeze-drying biological matrix is an important method for long-term storage of biological matrix, especially for some unstable substances, it is particularly important to keep the freeze-dried powder in a vacuum environment. Therefore, during the freeze-drying process of biological samples, the rubber plug capping is an important step. After the biological sample is prepared and divided into penicillin bottles according to the process, the rubber plug needs to be half-inserted into the bottle opening, so that the air in the bottle can communicate with the outside. Then the penicillin bottle is placed in the freeze-drying machine, and the door of the freeze-drying machine is kept sealed. After the freeze-drying machine runs the freeze-drying program, it will sequentially cool, vacuumize and increase the temperature according to the preset program steps.

[0003] The existing Chinese patent with publication number CN213832542U discloses a penicillin bottle tray. The penicillin bottle tray includes a tray body, which includes a side baffle, a rear baffle and a bottom plate. In the initial state, the support plate is located in the cavity of the shelf body and is clamped by the clamping piece. During use, the clamping groove part of the tray body can be lapped on the freeze-drying machine shelf, and the elastic push rod is pushed, so that the end of the elastic push rod pushes the push plate of the clamping piece, and the clamping plate rotates around the pivot, and the clamping plate of the clamping piece is separated from the clamping position of the support plate. The support plate is extended under the action of the spring, thereby supporting the bottom of the tray body. The tray body can be stably connected with the freeze-drying machine shelf without manual pushing, and the operation of the operator supporting the tray body is saved. The support plate supports the tray body to ensure that the tray body is flush with the freeze-drying machine shelf, and the operation is more simple and labor-saving.

[0004] Because the air in the penicillin bottle communicates with the space in the freeze-drying machine, the water in the matrix sublimates during the freeze-drying process, and the matrix becomes freeze-dried powder. At this time, the penicillin bottles in the freeze-drying machine are in a vacuum state, and the rubber plugs are fully inserted using the hydraulic gland device in the freeze-drying machine, so that the penicillin bottles are isolated from the space in the freeze-drying machine, and the vacuum in the penicillin bottles is maintained. The freeze-drying machine valve is opened to release the vacuum, and the freeze-dried penicillin bottles are taken out after the pressure returns to normal. Generally, a large number of penicillin bottles are freeze-dried at one time, and half-inserting the rubber plugs into the penicillin bottles before freeze-drying becomes a difficult problem. If the rubber plug is inserted too low, the air in the penicillin bottle cannot communicate with the outside, and the water cannot be removed by the freeze-drying machine, resulting in freeze-drying failure. If the rubber plug is inserted too high, the rubber plug may fall off during the final hydraulic gland device capping process, and the final sealing cannot be performed.

[0005] Therefore, the inventor believes that it is necessary to provide a freeze-drying tray for a vial bottle with a height limiting device, which limits half-sealing and full-sealing during a vial bottle stopper sealing process, ensures uniformity of the vial bottle stopper sealing operation, reduces misoperation, ensures smooth freeze-drying process, and reduces the rate of defective products. The utility model discloses

[0006] In view of the defects in the prior art, the utility model discloses a freeze-drying tray for a vial bottle with a height limiting device.

[0007] According to the freeze-drying tray for a vial bottle with a height limiting device, the two ends of any baffle strip are respectively inserted into a group of corresponding sockets, and a vial bottle placing space is formed between two adjacent baffle strips.

[0008] The socket comprises two upper and lower clamping grooves, when the baffle strip is inserted into the upper clamping groove of the socket, the height of the top end of the baffle strip is consistent with the height of the half-sealed stopper of the vial bottle.

[0009] When the baffle strip is inserted into the lower clamping groove of the socket, the height of the top end of the baffle strip is consistent with the height of the sealed stopper of the vial bottle.

[0010] Preferably, the socket is in the shape of an inverted F, comprising a vertical groove and two transverse clamping grooves in communication with the vertical groove, and the baffle strip can move up and down in the vertical groove.

[0011] Preferably, the distance between the end of the transverse clamping groove of the two sockets located at the edge of the side plate and the end of the side plate is consistent with the diameter of the vial bottle.

[0012] Preferably, the distance between the two adjacent sockets is consistent with the diameter of the vial bottle.

[0013] Preferably, the baffle strip is in interference fit with the upper clamping groove or the lower clamping groove of the socket.

[0014] Preferably, the socket is arranged in the lower half of the side plate.

[0015] Preferably, the baffle strip is in the shape of a rectangular plate, the two ends of the baffle strip are formed with protrusions, and the protrusions are in clamping fit with the upper clamping groove or the lower clamping groove of the socket.

[0016] Preferably, the protrusions are arranged at the lower end of the end of the baffle strip.

[0017] Preferably, the baffle strip comprises a metal baffle strip, and the thickness of the baffle strip is 1-3 mm.

[0018] Preferably, the socket is in the shape of "I" or "匚".

[0019] Compared with the prior art, the utility model has the following beneficial effects:

[0020] By arranging a socket on the side plate of the freeze-drying tray, and the socket includes a vertical groove and at least two transverse card slots communicated with it, the baffle strip can move in the socket and maintain different heights, which can limit the semi-capping and full-capping during the capping process of the vial, so as to ensure the uniformity of the rubber stopper capping action of the vial, reduce misoperation, ensure the smooth progress of the freeze-drying process, and reduce the defective rate. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] By reading the detailed description of the non-restrictive embodiments with reference to the following drawings, other features, objects and advantages of the present utility model will become more obvious:

[0022] <00?00048>It is a schematic structure diagram mainly showing the freeze-drying tray of the present utility model;

[0023] Figure 2 [[ID=2?]]It is a schematic structure diagram mainly showing the baffle strip of the present utility model;

[0024] Figure 3 It is a schematic diagram mainly showing the baffle strip when the rubber stopper is semi-capped;

[0025] Figure 4 It is a schematic diagram mainly showing the baffle strip after the freeze-drying is completed and the cap is pressed.

[0026] Reference numerals: <?

[0027] Freeze-drying tray 1, Baffle strip 2 DETAILED DESCRIPTION OF THE EMBODIMENTS [[ID=?8]]

[0028] The present utility model will be described in detail below with reference to specific embodiments. The following embodiments will help those skilled in the art to further understand the present utility model, but do not limit the present utility model in any form. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present utility model, several changes and improvements can still be made. These all belong to the protection scope of the present utility model.

[0029] Such as Figures 1-4As shown in the figure, a freeze-dried tray for vials with a height-limiting device according to the present utility model includes a freeze-dried tray 1 and baffle strips 2. The freeze-dried tray 1 includes a bottom plate and four vertical side plates. Multiple sets of sockets are provided on a set of opposite side plates. A plurality of baffle strips 2 are installed in parallel on the freeze-dried tray 1. The two ends of any baffle strip 2 are respectively inserted into a set of corresponding sockets, and a vial placement space is formed between two adjacent baffle strips 2. The socket includes two upper and lower card slots. When the baffle strip 2 is inserted into the upper card slot of the socket, the top height of the baffle strip 2 is the same as the height of the vial after the rubber stopper is half-inserted. When the baffle strip 2 is inserted into the lower card slot of the socket, the top height of the baffle strip 2 is the same as the height of the vial when the rubber stopper is sealed.

[0030] The socket is in an inverted F shape and includes a vertical slot and two horizontal card slots connected thereto. The baffle strip 2 can move up and down in the vertical slot.

[0031] The distance between the end of the horizontal card slot of the two sockets at the edge of the side plate and the end of the side plate is the same as the diameter of the vial. The distance between two adjacent sockets is the same as the diameter of the vial. In this way, when the baffle strip 2 is inserted into the horizontal card slot, it just holds the vial, and at the same time, the vial can also ensure the stability of the baffle strip 2. When it is necessary to take or place the vial, the baffle strip 2 is placed and moved into the vertical slot of the inverted F socket, which is convenient for taking and placing the vial.

[0032] Preferably, the baffle strip 2 has an interference fit with the upper or lower card slot of the socket, and a little force is required to move the baffle strip 2 away, so as to ensure the firmness of the connection between the baffle strip 2 and the side plate.

[0033] Generally, the socket is arranged in the lower half of the side plate, which can make the baffle strip 2 stand more firmly.

[0034] The baffle strip 2 is in the shape of a rectangular plate. Protrusions are formed at both ends of the baffle strip 2, and the protrusions are in snap-fit with the upper or lower card slot of the socket. Preferably, the protrusions are arranged at the lower end of the end of the baffle strip 2, which is convenient for production and manufacturing.

[0035] The baffle strip 2 includes a metal baffle strip, and the thickness of the baffle strip 2 is from 1 to 3 mm. The baffle strip 2 should be made of a hard and low-temperature-resistant material, such as stainless steel, and its length and height need to match the sizes of the freeze-dried tray 1 and the vial.

[0036] The design of the socket can have various forms. In other specific embodiments, the socket is in the shape of "I", "匚", etc. When the shape of the socket is adjusted, the position of the protrusion of the baffle strip 2 also needs to be adjusted to ensure the stability of the baffle strip 2. The socket design needs to ensure that it has a vertical slot and at least two horizontal card slots connected thereto, that is, it can be adjusted in two height positions up and down to hold the heights of the half-inserted and fully tightened rubber stoppers, and it needs to be adjusted slightly horizontally left and right to facilitate the taking and placing of the freeze-dried vials.

[0037] The operation method of the present application is as follows: when the action of half-plugging the rubber plug is needed, the baffle strip 2 is adjusted into the upper clamping groove of the spout, at this time the height of the baffle strip 2 is just consistent with the height after the rubber plug is half-plugged, which can prevent the rubber plug from being plugged too low or too high. After the half-plugging is completed, the baffle strip 2 is adjusted into the lower clamping groove of the spout, at this time the height of the baffle strip 2 is consistent with the height when the rubber plug is sealed, so that the rubber plug cannot be tightly plugged due to the obstruction of the baffle strip 2 when the hydraulic device is pressed down, and the vial is sealed, thereby ensuring that the sealing of the freeze-dried vial is uniform.

[0038] If the height of the baffle strip 2 is too high, the rubber plug cannot be completely plugged in, and if the height is too low, since the pressing process of the hydraulic device is manually controlled, and the area of the pressing plate is large, when the number of vials in the freeze-dried tray 1 is small and cannot cover the entire freeze-dried tray 1, the pressing plate may be tilted, the rubber plug of the vial may be pressed in unevenly, or the vial may be crushed.

[0039] The present application solves the difficulty of the action of half-plugging the rubber plug in the freeze-drying process by the height-adjustable baffle strip 2, can better control the quality of the action of half-plugging the rubber plug, ensure that the action of plugging the rubber plug of the vial is uniform and consistent, reduce misoperation, ensure that the freeze-drying process proceeds smoothly, and reduce the rate of defective products.

[0040] In the description of the present application, it should be understood that the orientations or positional relationships indicated by the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer" and the like are based on the orientations or positional relationships shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and therefore cannot be understood as indicating or implying that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the present application.

[0041] The specific embodiments of the present application are described above. It should be understood that the present application is not limited to the specific implementation described above, and those skilled in the art can make various changes or modifications within the scope of the claims, which does not affect the essential content of the present application. In the case of no conflict, the embodiments of the present application and the features in the embodiments can be arbitrarily combined with each other.

Claims

1. A vial freeze-drying tray with a height limiting device, characterized in that, Comprising: A freeze-drying tray (1) and baffle strips (2), the freeze-drying tray (1) includes a bottom plate and four vertical side plates, multiple groups of sockets are provided on a set of opposite side plates, and multiple baffle strips (2) are installed in parallel on the freeze-drying tray (1), and both ends of any baffle strip (2) are respectively inserted into a set of corresponding sockets, and a space for placing vials is formed between adjacent two baffle strips (2); The socket includes two upper and lower card slots. When the baffle strip (2) is inserted into the upper card slot of the socket, the top height of the baffle strip (2) is consistent with the height of the vial after the rubber stopper is semi-inserted; When the baffle strip (2) is inserted into the lower card slot of the socket, the top height of the baffle strip (2) is consistent with the height of the vial when the rubber stopper is sealed; The socket is in an inverted F shape, including a vertical slot and two transverse card slots communicated with it, and the baffle strip (2) can move up and down in the vertical slot; The baffle strip (2) is in a rectangular plate shape, and protrusions are formed at both ends of the baffle strip (2), the protrusions are arranged at the lower ends of the ends of the baffle strip (2), and the protrusions are in snap-fit with the upper card slot or the lower card slot of the socket.

2. The vial freeze-drying tray with height limiting device as described in claim 1, characterized in that, The distance between the end of the transverse card slot of the two sockets at the edge of the side plate and the end of the side plate is consistent with the diameter of the vial.

3. The vial freeze-drying tray with height limiting device as described in claim 1, characterized in that, The distance between adjacent two sockets is consistent with the diameter of the vial.

4. The vial freeze-drying tray with height limiting device as described in claim 1, characterized in that, The baffle strip (2) is in interference fit with the upper card slot or the lower card slot of the socket.

5. The vial freeze-drying tray with height limiting device as described in claim 1, characterized in that, The socket is arranged in the lower half of the side plate.

6. The capping device of claim 1, wherein the capping device is a capping device for a lyophilization tray of a plurality of vials. The baffle strip (2) includes a metal baffle strip, and the thickness of the baffle strip (2) is 1-3 mm.

7. The vial freeze-drying tray with height limiting device as described in claim 1, characterized in that, The socket is in an "I" shape or a "匚" shape.

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