Economical and convenient mouse tail vein injection device
By designing an injection device using a binding tube and a stone-plastic finger ring, the problems of unstable fixation and limited light exposure during tail vein injection in mice were solved, achieving stable fixation and clear observation, thus improving the accuracy and safety of the experiment.
Patent Information
- Application Number
- CN202422210640.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-09
- Publication Date
- 2025-12-02
- Estimated Expiration
- 2034-09-09
AI Technical Summary
Current techniques for tail vein injection in mice are difficult due to the challenges of unstable fixation and limited lighting conditions, which affect the accuracy and safety of the experiment.
An injection device comprising a binding tube and a stone-plastic finger ring was designed. The binding tube is transparent and hollow with a vent hole. The tube cap is connected to the stone-plastic finger ring by threads. The stone-plastic finger ring has a groove for placing a yellow light strip to irradiate the tail vein.
It improves the accuracy and safety of tail vein injection in mice, adapts to various experimental conditions, prevents mice from struggling and biting, and ensures the smooth progress of experiments.
Smart Images
Figure CN223614966U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to an auxiliary tool for mouse experiments, specifically an economical and convenient tail vein injection device for mice. Background Technology
[0002] Mice are small, have a short growth period, high reproductive rate, low cost, and are easy to control, making them one of the most commonly used laboratory animals. Blood collection via the mouse tail vein, drug administration, or cell transplantation are common techniques in experimental research, and the success of these procedures largely determines the achievement of desired experimental results.
[0003] The applicant has discovered that the prior art has at least the following technical problems:
[0004] 1. In the existing technology; mice are small in size, sensitive to external stimuli, timid and easily startled. In addition, the veins in the tail of mice are very delicate, making it difficult to inject through the tail vein in medical experiments. Traditionally, the experimenter holds the mouse so that the tail cannot move during the injection. However, this method can lead to the experimenter being bitten by the mouse. At the same time, the existing mouse restraints cannot be perfectly matched to the mice required for the experiment, and cannot ensure that all experimental mice are properly restrained. This results in the mice not being properly restrained, causing them to struggle and their tails to slip off, leading to experimental failure. Alternatively, if the mice are restrained too tightly during the experiment, they may die, making it impossible to ensure the smooth progress of subsequent experiments.
[0005] 2. In existing technologies, researchers have employed various methods to dilate the tail veins of mice for observation, such as warm water baths, tungsten filament lamp irradiation, or disinfection with alcohol swabs. While these methods can help dilate blood vessels to some extent, their effectiveness is still limited by ambient lighting conditions. In low-light or complex experimental environments, the effectiveness of these methods is often significantly reduced, severely impacting the accuracy and efficiency of the experiment. Utility Model Content
[0006] The purpose of this invention is to provide an economical and convenient mouse tail vein injection device to solve the technical problem that the mouse tail vein is not easily observed during mouse tail vein injection.
[0007] To achieve the above objectives, the present invention provides the following technical solution:
[0008] This utility model provides an economical and convenient mouse tail vein injection device, including a restraint tube for fixing the mouse and a stone-plastic finger ring for fixing the mouse tail and for tail vein injection. The restraint tube is hollow and transparent, specifically including a tube body and a tube cap. The tube body has a cavity, and the bottom of the tube body is a conical part. The tube body is provided with several ventilation holes for the mouse to breathe freely. The tube cap has a through hole, the diameter of which matches the diameter of the mouse tail root, so that the mouse tail can pass through the tube cap and wrap around the stone-plastic finger ring.
[0009] Furthermore, a groove is provided on one side of the stone-plastic ring, and a light strip is placed in the groove, with the mouse's tail straightened and placed on the light strip.
[0010] Furthermore, the light strip is a yellow light strip, and the tail vein of the mouse can be clearly seen through the projection of the yellow light.
[0011] Furthermore, the pipe cap and the pipe body are connected at the pipe opening by threads.
[0012] Furthermore, the number of vent holes is set to 8-15, and the diameter of each vent hole is 3-4 mm.
[0013] Furthermore, the binding tube is a 50 mL EP centrifuge tube.
[0014] Based on the above technical solution, the embodiments of this utility model can produce at least the following technical effects:
[0015] (1) The present invention provides an economical and convenient mouse tail vein injection device. This device facilitates the fixation of mice and leaves the mouse tail outside the restraint tube, which can prevent the mouse from biting the experimenter and make it convenient for the experimenter to perform tail vein injection. In addition, the design of the restraint tube and the stone-plastic finger ring makes the mouse more stable during the experiment and improves the accuracy of injection.
[0016] (2) The economical and convenient mouse tail vein injection device provided by this utility model allows for clear visualization of the mouse's tail vein by setting a groove on a stone-plastic finger ring and placing a yellow light strip thereon, utilizing the transmission of yellow light. This method is non-invasive, harmless, and not limited by the lighting conditions of the injection environment, making it adaptable to various experimental conditions. The transmission of yellow light makes the tail vein more clearly visible, greatly improving the accuracy and efficiency of the experiment.
[0017] (3) The present invention provides an economical and convenient mouse tail vein injection device, the design of which takes into account the safety of the experimenters and the mice. The design of the restraint tube and the tube cap prevents the mice from struggling and biting during the injection process, while the setting of the vent hole ensures the normal breathing of the mice during the restraint process, thus improving the safety of the experiment. Attached Figure Description
[0018] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.
[0019] Figure 1 This is a schematic diagram of the mouse tail vein injection device of this utility model;
[0020] Figure 2 This is a side view of the mouse tail vein injection device of this utility model.
[0021] In the above figures, the component names corresponding to the reference numerals are as follows:
[0022] 100. Binding tube; 101. Tube body; 102. Tube cap; 103. Conical part; 104. Vent hole; 105. Through hole; 200. Stone-plastic ring; 201. Groove; 202. Light strip. Detailed Implementation
[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only a part of the embodiments of the present utility model, and not all of them. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model. In addition, the technical solutions of the various embodiments can be combined with each other, but this must be based on the ability of those skilled in the art to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be considered that such combination of technical solutions does not exist and is not within the protection scope claimed by the present utility model.
[0024] In this utility model, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.
[0025] This utility model is achieved through the following technical solution:
[0026] Example 1:
[0027] This embodiment provides an economical and convenient mouse tail vein injection device, such as... Figure 1 As shown, the device includes a restraint tube 100 for fixing a mouse and a stone-plastic finger ring 200 for fixing the mouse tail and for tail vein injection. The restraint tube 100 is hollow and transparent, specifically comprising a tube body 101 and a cap 102. The cap 102 and the tube body 101 are connected at the opening by threads. The tube body 101 has a cavity inside, and the bottom of the tube body 101 is a conical part 103. The tube body 101 is provided with several ventilation holes 104 for the mouse to breathe freely. The cap 102 has a through hole 105, the diameter of which matches the diameter of the base of the mouse tail, so that the mouse tail can pass through the cap 102 and wrap around the stone-plastic finger ring 200. This device facilitates the fixation of the mouse while leaving the mouse tail outside the restraint tube, which can prevent the mouse from biting the experimenter and make it convenient for the experimenter to perform tail vein injection. In addition, the design of the restraint tube and the stone-plastic finger ring makes the mouse more stable during the experiment and improves the accuracy of the injection.
[0028] In this embodiment, 15 ventilation holes 104 are provided to facilitate free breathing of the mice, and the diameter of each ventilation hole 104 is 3 mm.
[0029] In this embodiment, the binding tube 100 is a 50mL EP centrifuge tube.
[0030] The method for manufacturing a mouse tail vein injection device includes the following steps:
[0031] Step 1: Mouse restraint tube: Use a welding torch to puncture several holes in the wall of a 50ml EP centrifuge tube as ventilation holes for the mouse; puncture a larger hole in the cap of the 50ml EP centrifuge tube as a through hole so that the mouse's tail can pass through the cap.
[0032] Step 2: Injecting a stone-plastic ring into the tail vein: Make a ring using stone-plastic clay according to the size of the left middle finger. Make a suitable groove on the surface of the ring to embed the yellow light strip, and this groove can also accommodate the mouse's tail.
[0033] Procedure for using the mouse tail vein injection device:
[0034] Place the mouse inside the restraint tube, with its tail protruding through the tube cap hole. Place the tail vein injection stone-plastic finger ring on the index finger of your left hand, straighten the mouse's tail, and place it on the yellow light strip. The tail vein of the mouse can be clearly seen through the projection of the yellow light.
[0035] Example 2:
[0036] The difference between this embodiment and Embodiment 1 is that, as Figure 2 As shown in this embodiment, in order to clearly visualize the mouse's tail vein under different experimental conditions and environments, a groove 201 is provided on one side of the stone-plastic finger ring 200. A light strip 202 is placed in the groove 201, and the mouse's tail is stretched straight and placed on the light strip 202. The light strip 202 is a yellow light strip, and the mouse's tail vein is clearly visible through the projection of the yellow light. This method is non-invasive, harmless, and not limited by the lighting conditions of the injection environment, making it adaptable to various experimental conditions.
[0037] In this embodiment, eight ventilation holes 104 are provided to facilitate free breathing in mice, and each ventilation hole 104 has a diameter of 4 mm. The other structures and working principles of this embodiment are the same as those in Embodiment 1, and will not be repeated here.
[0038] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.
Claims
1. An economical and convenient tail vein injection device for mice, characterized in that, The device includes a restraint tube (100) for fixing mice and a stone-plastic finger ring (200) for fixing the mouse tail and for tail vein injection. The restraint tube (100) is hollow and transparent, specifically including a tube body (101) and a tube cap (102). The tube body (101) has a cavity inside, and the bottom of the tube body (101) is a conical part (103). The tube body (101) is provided with several ventilation holes (104) for the mouse to breathe freely. The tube cap (102) has a through hole (105). The diameter of the through hole (105) matches the diameter of the root of the mouse tail so that the mouse tail can pass through the tube cap (102) and wrap around the stone-plastic finger ring (200).
2. The economical and convenient mouse tail vein injection device according to claim 1, characterized in that, The stone-plastic ring (200) has a groove (201) on one side, and a light strip (202) is placed in the groove (201). The mouse's tail is straightened and placed on the light strip (202).
3. The economical and convenient mouse tail vein injection device according to claim 2, characterized in that, The light strip (202) is a yellow light strip, through which the tail vein of the mouse can be clearly seen.
4. The economical and convenient mouse tail vein injection device according to claim 1, characterized in that, The pipe cap (102) and the pipe body (101) are connected at the pipe opening by threads.
5. The economical and convenient mouse tail vein injection device according to claim 1, characterized in that, The number of vent holes (104) is set to 8-15, and the diameter of each vent hole (104) is 3-4 mm.
6. The economical and convenient mouse tail vein injection device according to claim 1, characterized in that, The binding tube (100) is a 50 mL EP centrifuge tube.