Semi-automatic pelleter

By designing an array of slide placement slots and pick-up/drop-off notches in a semi-automatic slide preparation machine, combined with a humidification and dehumidification module and a temperature sensor, the problems of inconvenient manual placement of slides and unstable temperature and humidity in the slide tray structure are solved, achieving efficient slide processing and a stable operating environment.

CN223637199UActive Publication Date: 2025-12-05SHANGHAI LECHEN BIOLOGICAL SCI & TECH
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Patent Information

Application Number
CN202422784869.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-14
Publication Date
2025-12-05
Estimated Expiration
2034-11-14

AI Technical Summary

Technical Problem

In existing technologies, the slide tray structure is not convenient for manual placement of slides, has low throughput, unstable heating and dehumidification effects, and poor cooling effect.

Method used

A semi-automatic slide preparation machine was designed, comprising components such as an equipment compartment, a process control device, a three-dimensional motion mechanism, a liquid-dispensing robotic arm, a sample processing platform, and a slide tray. By setting arrayed slide placement slots and pick-up/placement notches on the slide tray, combined with a humidification module, a dehumidification module, and a temperature sensor, stable temperature and humidity control is achieved, and the three-dimensional motion mechanism and liquid-dispensing robotic arm improve operational efficiency.

Benefits of technology

It increased the throughput of glass slides, ensured the stability of temperature and humidity, and improved the stability and efficiency of the operating environment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a semi-automatic pelleter which comprises an equipment cabin, a processing flow control device, a three-dimensional movement mechanism, a liquid adding mechanical arm, a sample processing platform, a blood collection tube sample frame, a suction head bracket, a slide placing plate groove, a slide placing plate, a humidifying module and a dehumidifying module, a temperature and humidity sensor and a plurality of ventilation openings are arranged on the side wall of the equipment cabin, a sample processing platform is arranged at the bottom of an inner cavity of the equipment cabin, and the sample processing platform is used for placing or installing a blood collection tube sample frame, a suction head support, a slide placing plate groove and a slide placing plate; a humidification module and a dehumidification module are arranged below the sample treatment platform; and the heating module and the temperature sensor are correspondingly arranged below the slide tray placing groove. The glass slide placing plate facilitates overall manual taking and placing, the processing flux of the glass slides is improved, the ventilation openings for humidification and dehumidification are formed in the side wall of the equipment cabin in a surrounding mode, and the temperature and humidity stability of the operation environment is improved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to a biological sample processing instrument, concretely relates to a semi-automatic film maker. BACKGROUND

[0002] The cell sample processing equipment can automatically complete the harvesting process of metaphase chromosomes and cells of peripheral blood, bone marrow, amniotic fluid, umbilical cord blood, villus cells or other samples, and is applied to chromosome karyotype, micronucleus and FISH analysis. The harvesting of cells for cytogenetic analysis is a multi-step process, which can be manually operated or completed through an automatic instrument. At present, such biological sample processing instruments have initially realized the automation of sample processing.

[0003] In the automatic drop film process of peripheral blood lymphocyte samples in cytogenetic analysis, a dispersion chamber is used to provide a stable drop film temperature and humidity condition for the cell samples on the glass slide to prepare sample suspension drop film. The current scheme is to set a slide tray on the dispersion chamber, place the glass slide on the slide tray, and set a heating device and a cooling device at the bottom of the dispersion chamber. However, the current heating and humidifying effect of the dispersion chamber is unstable, and the cooling effect is poor. The structure of the slide tray is not convenient for manual placement of the glass slide. How to improve the processing throughput of the glass slide and provide stable temperature and humidity control is a technical problem to be solved. UTILITARY MODEL

[0004] In view of the problems existing in the prior art, the utility model provides a semi-automatic film maker, which is used to solve the technical problems that the structure of the slide tray is not convenient for manual placement of the glass slide, the processing throughput of the glass slide is low, the current heating and dehumidifying effect of the dispersion chamber is unstable, and the cooling effect is poor.

[0005] In order to achieve the above purpose, the utility model adopts the following technical scheme:

[0006] A semi-automatic film maker, the semi-automatic film maker includes an equipment cabin, a processing flow control device, a three-dimensional motion mechanism, a liquid adding mechanical arm, a sample processing platform, a blood collection tube sample rack, a suction head support, a slide tray groove, a slide tray, a humidifying module, a dehumidifying module, a humidity sensor, a heating module and a temperature sensor.

[0007] The side wall of the equipment cabin is provided with the humidity sensor and a plurality of ventilation openings, the inner cavity bottom of the equipment cabin is provided with the sample processing platform, and the sample processing platform is used to place or install the blood collection tube sample rack, the suction head support, the slide tray groove and the slide tray; the slide tray groove extends to below the sample processing platform, and the slide tray is arranged in the groove of the slide tray groove; and the lower portion of the sample processing platform is provided with the humidifying module and the dehumidifying module.

[0008] The heating module and the temperature sensor are arranged below the slide tray groove;

[0009] The top surface of the slide tray is provided with a plurality of arrayed slide placing grooves, and a taking and placing notch is arranged on the same side of the slide placing groove, the taking and placing notch penetrates in and out in the radial direction of the slide tray, and the bottom of the taking and placing notch is flush with the groove bottom of the slide placing groove.

[0010] Further, the slide tray is rectangular, and one handle is arranged on each side in the radial direction of the slide tray.

[0011] Further, the groove bottom of the slide placing groove is inclined downward from one side of the taking and placing notch to the side away from the taking and placing notch.

[0012] Further, the liquid adding mechanical arm is arranged above the sample processing platform, and the liquid adding mechanical arm can move between the blood collection tube sample rack, the suction head support and the slide tray, the liquid adding mechanical arm sucks one suction head on the suction head support and sucks the culture medium from the culture medium container, the liquid adding mechanical arm sucks one suction head on the suction head support and sucks the sample from the blood collection tube sample rack and transfers the sample to the slide on the slide tray.

[0013] Further, the liquid adding mechanical arm is provided with an automatic barcode input module, the automatic barcode input module can scan and obtain the barcode of each blood collection tube on the blood collection tube sample rack, and the automatic barcode input module can scan and obtain the barcode of each slide on the slide tray.

[0014] Further, the two ends of the three-dimensional motion mechanism are connected to the equipment cabin and located above the sample processing platform, the liquid adding mechanical arm is installed on the three-dimensional motion mechanism, the three-dimensional motion mechanism drives the liquid adding mechanical arm to move, the processing flow control device is arranged outside the equipment cabin, and the processing flow control device is in signal connection with the liquid adding mechanical arm.

[0015] Further, the semi-automatic slide maker further comprises a waste gas adsorption treatment module; the waste gas adsorption treatment module is arranged on the top of the equipment cabin, the waste gas adsorption treatment module serves as an absorption and conveying device for gas in the equipment cabin; the waste gas adsorption treatment module comprises a waste gas exhaust fan, a waste gas adsorbent and a fan outer frame fixing frame; the waste gas exhaust fan is installed on the top of the equipment cabin through the fan outer frame fixing frame; and the waste gas adsorbent is arranged below the waste gas exhaust fan.

[0016] Further, the semi-automatic slide maker further comprises a UV disinfection module composed of multiple UV lamps, which is used for disinfecting the operation space area in the equipment cabin, the UV lamps are installed below the top of the equipment cabin, and the switches of the UV lamps are controlled by signal connection with the control system.

[0017] The semi-automatic slide maker provided by the application has the advantages that the slide tray is arranged on the sample processing platform, a plurality of array-arranged slide placing grooves are arranged on the top surface of the slide tray, the same side of the slide placing grooves is provided with a taking and placing notch, the slide can be conveniently taken and placed on the slide tray, the slide tray is convenient for being manually taken and placed as a whole, the processing flux of the slide is improved, the ventilation openings for humidification and dehumidification are arranged around the side wall of the equipment cabin, the humidity of the whole equipment cabin is controlled, and the temperature and humidity stability of the operation environment is improved. BRIEF DESCRIPTION OF DRAWINGS

[0018] Figure 1 It is an overall structural schematic view of the semi-automatic slide maker.

[0019] Figure 2 It is a top view of the sample processing platform.

[0020] Figure 3 It is a schematic view of the internal structure of the sample processing platform.

[0021] Figure 4 It is a bottom view of the sample processing platform.

[0022] Figure 5 It is a schematic view of the dehumidification module.

[0023] Figure 6 It is a schematic view of the blood collection tube sample rack.

[0024] Figure 7 It is a schematic view of the slide tray.

[0025] Figure 8 It is a schematic view of the liquid adding mechanical arm arranged on the three-dimensional movement mechanism.

[0026] Figure 9 It is a schematic view of the waste gas adsorption treatment module.

[0027] Figure 10 It is a schematic view of the UV disinfection module.

[0028] The symbols in the drawing are as follows:

[0029] Device cabin 1, processing flow control device 2, three-dimensional motion mechanism 3, liquid adding mechanical arm 4, automatic barcode input module 41, sample processing platform 5, blood collection tube sample rack 6, suction head support 7, slide tray groove 8, slide tray 9, slide tray placing groove 91, taking and placing notch 92, handle 93, humidification module 10, dehumidification module 11, heating module 12, temperature sensor 13, waste gas adsorption treatment module 14, waste gas exhaust fan 141, waste gas adsorbent 142, fan outer frame fixing frame 143, ultraviolet disinfection module 15, ultraviolet lamp 151. DETAILED DESCRIPTION

[0030] The utility model will be further explained in connection with the drawings.

[0031] In this embodiment, referring to Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 、 Figure 5 , a semi-automatic slide maker comprises a device cabin 1, a processing flow control device 2, a three-dimensional motion mechanism 3, a liquid adding mechanical arm 4, a sample processing platform 5, a blood collection tube sample rack 6, a suction head support 7, a slide tray groove 8, a slide tray 9, a humidification module 10, a dehumidification module 11, a humidity sensor, a heating module 12 and a temperature sensor 13. Preferably, the humidification module 10 is a gasification humidifier, the dehumidification module 11 is a fan, and the heating module 12 is an electric heater.

[0032] The side wall of the device cabin 1 is provided with the humidity sensor and a plurality of ventilation openings, water vapor is blown out of the ventilation openings to control the humidity of the entire device cabin 1, the inner cavity bottom of the device cabin 1 is provided with the sample processing platform 5, the sample processing platform 5 is used for placing or mounting the blood collection tube sample rack 6, the suction head support 7, the slide tray groove 8 and the slide tray 9, the slide tray groove 8 extends to below the sample processing platform 5, the slide tray 9 is arranged at the groove opening of the slide tray groove 8, the humidification module 10 and the dehumidification module 11 are arranged below the sample processing platform 5, and the heating module 12 and the temperature sensor 13 are arranged below the slide tray groove 8. The temperature sensor 13 and the humidity sensor can be connected to the processing flow control device to report the detected temperature and humidity in the device cabin, the processing flow control device adjusts the humidification module 10, the dehumidification module 11 and the heating module 12 in real time according to the temperature and humidity in the device cabin. The humidification module 10, the dehumidification module 11 and the humidity sensor work cooperatively to meet the humidity requirement, and the heating module 12 and the temperature sensor 13 work cooperatively to meet the temperature requirement.

[0033] Referring to Figure 2 、 Figure 6The top surface of the slide tray 9 is provided with a plurality of arrayed slide placing grooves 91, and the same side of the slide placing grooves 91 is provided with a taking and placing notch 92 which penetrates in and out in the radial direction of the slide tray 9, and the bottom of the taking and placing notch 92 is flush with the groove bottom of the slide placing groove 91. The taking and placing notch 92 can facilitate the taking and placing of the slide in the slide placing groove 91 on the slide tray 9, and the slide tray 9 is convenient to take and place as a whole, thereby improving the processing throughput of the slide.

[0034] Referring to Figure 2 , Figure 6 In the embodiment, the slide tray 9 is rectangular, and each side of the radial direction of the slide tray 9 is provided with a handle 93. The handle 93 can facilitate the taking and placing of the slide tray 9 as a whole, thereby improving the processing throughput of the slide.

[0035] Referring to Figure 2 , Figure 6 In the embodiment, the groove bottom of the slide placing groove 91 is inclined downward from one side of the taking and placing notch 92 to the side far away from the taking and placing notch 92. This structure can make the slide in the slide placing groove 91 tilt up at one side of the taking and placing notch 92, thereby facilitating the taking of the edge of the slide from the position of the taking and placing notch 92.

[0036] Referring to Figure 8 In the embodiment, the liquid adding mechanical arm 4 is arranged above the sample processing platform 5, and the liquid adding mechanical arm 4 can move between the blood collection tube sample rack 6, the suction head support 7 and the slide tray 9. The liquid adding mechanical arm 4 sucks a suction head on the suction head support 7, sucks the sample in the blood collection tube in the blood collection tube sample rack 6, and transfers the sample to the slide on the slide tray 9.

[0037] In the embodiment, the liquid adding mechanical arm 4 is provided with an automatic barcode input module 41 which can scan and obtain the barcode of each blood collection tube on the blood collection tube sample rack 6, and the automatic barcode input module 41 can scan and obtain the barcode of each slide on the slide tray 9. In this way, the barcode of the blood collection tube and the barcode of the slide can be associated with each other, the blood collection tube and the slide can be matched one by one, and the traceability management is facilitated.

[0038] In the embodiment, the slide tray 9 can also be manually operated. When manually operated, the automatic barcode input module 41 does not need to be used.

[0039] Referring to Figure 1 , Figure 8In the embodiment, the two ends of the three-dimensional movement mechanism 3 are connected to the equipment cabin 1 and located above the sample processing platform 5, the liquid adding mechanical arm 4 is installed on the three-dimensional movement mechanism 3, the three-dimensional movement mechanism 3 drives the liquid adding mechanical arm 4 to move, and the processing flow control device 2 is arranged outside the equipment cabin 1 and signal-connected with the liquid adding mechanical arm 4.

[0040] The three-dimensional movement mechanism 3 is composed of an X-axis motor, a Y-axis motor, a Z-axis motor and corresponding transmission mechanisms, and the combination movement of the three motors realizes the transfer operation of the liquid adding mechanical arm 4.

[0041] Referring to Figure 9 In the embodiment, the semi-automatic slide maker further comprises a waste gas adsorption and treatment module 14; the waste gas adsorption and treatment module 14 is arranged at the top of the equipment cabin 1, and serves as a gas absorption and conveying device in the equipment cabin 1; the waste gas adsorption and treatment module 14 comprises a waste gas exhaust fan 141, a waste gas adsorbent 142 and a fan outer frame fixing frame 143; the waste gas exhaust fan 141 is installed at the top of the equipment cabin 1 through the fan outer frame fixing frame 143; and the waste gas adsorbent 142 is arranged below the waste gas exhaust fan 141. The waste gas adsorption and treatment module 14 can ensure that the gas in the equipment cabin 1 is treated and then discharged, thereby avoiding air pollution.

[0042] Referring to Figure 10 In the embodiment, the semi-automatic slide maker further comprises an ultraviolet disinfection module 15, which is composed of a plurality of ultraviolet lamps 151 and used for disinfecting the operation space region in the equipment cabin 1; the ultraviolet lamps 151 are installed below the top of the equipment cabin 1, and the switches of the ultraviolet lamps 151 are controlled by signal connection with the control system. The ultraviolet disinfection module 15 can disinfect the slide tray 9, the blood collection tube sample rack 6 and the suction head support 7 in the equipment cabin 1, thereby avoiding environmental pollution of the detection result.

[0043] The semi-automatic slide maker provided in the application comprises a sample processing platform 5, a slide tray 9 arranged on the sample processing platform 5, a plurality of arrayed slide placing grooves 91 arranged on the top surface of the slide tray 9, a take-and-place notch 92 arranged on the same side of the slide placing grooves 91, a liquid adding mechanical arm 4, a processing flow control device 2, a heating module 12, a temperature sensor 13, a humidifying module 10, a dehumidifying module 11 and an ultraviolet disinfection module 15.

[0044] The utility model embodiment has carried on the explanation above union the drawing, but the utility model is not limited to the above -mentioned embodiment, still can make multiple changes according to the utility model's invention creation's purpose, all should be the equivalent replacement mode for the change, the modification, the substitution, the combination or the simplification of the spirit essence and principle under the utility model technical scheme of according to the utility model, as long as the invention purpose of the utility model, as long as not departing from the technical principle and invention idea of the utility model, all belong to the protection scope of the utility model.

Claims

1. A semi-automatic tablet making machine characterized in that, The semi-automatic slide maker comprises a device cabin, a processing flow control device, a three-dimensional motion mechanism, a liquid adding mechanical arm, a sample processing platform, a blood collection tube sample rack, a suction head support, a slide tray groove, a slide tray, a humidification module, a dehumidification module, a humidity sensor, a heating module and a temperature sensor; The side wall of the device cabin is provided with the humidity sensor and a plurality of ventilation openings, and the inner cavity bottom of the device cabin is provided with the sample processing platform, which is used for placing or mounting the blood collection tube sample rack, the suction head support, the slide tray groove and the slide tray; the slide tray groove extends to below the sample processing platform, and the slide tray is arranged in the groove of the slide tray groove; The bottom of the sample processing platform is provided with the humidification module and the dehumidification module; The bottom of the slide tray groove is provided with the heating module and the temperature sensor; The top surface of the slide tray is provided with a plurality of arrayed slide placing grooves, the same side of the slide placing groove is provided with a taking and placing notch, the taking and placing notch penetrates in and out in the radial direction of the slide tray, and the bottom of the taking and placing notch is flush with the groove bottom of the slide placing groove.

2. The semi-automatic tablet maker according to claim 1, wherein The slide tray is rectangular, and one handle is arranged on each side in the radial direction of the slide tray.

3. The semi-automatic tablet maker according to claim 1, wherein, The groove bottom of the slide placing groove is inclined downward from one side of the taking and placing notch to the side away from the taking and placing notch.

4. The semi-automatic tablet maker according to claim 1, wherein The liquid adding mechanical arm is arranged above the sample processing platform, and the liquid adding mechanical arm can move between the blood collection tube sample rack, the suction head support and the slide tray; the liquid adding mechanical arm sucks one suction head on the suction head support and transfers the sample from the blood collection tube sample rack to the slide on the slide tray.

5. The semi-automatic tablet maker according to claim 4, wherein An automatic barcode input module is arranged on the liquid adding mechanical arm, the automatic barcode input module can scan and obtain the barcode of each blood collection tube on the blood collection tube sample rack, and the automatic barcode input module can scan and obtain the barcode of each slide on the slide tray.

6. The semi-automatic tablet maker according to claim 1, wherein Both ends of the three-dimensional motion mechanism are connected to the device cabin and located above the sample processing platform, the liquid adding mechanical arm is installed on the three-dimensional motion mechanism, the three-dimensional motion mechanism drives the liquid adding mechanical arm to move, the processing flow control device is arranged outside the device cabin, and the processing flow control device is signal connected with the liquid adding mechanical arm.

7. The semi-automatic tablet maker of claim 1, wherein, The semi-automatic slide maker further comprises a waste gas adsorption treatment module; the waste gas adsorption treatment module is arranged on the top of the device cabin, the waste gas adsorption treatment module serves as a gas absorption and conveying device in the device cabin; the waste gas adsorption treatment module comprises a waste gas exhaust fan, a waste gas adsorbent and a fan outer frame fixing frame; the waste gas exhaust fan is installed on the top of the device cabin through the fan outer frame fixing frame; and the waste gas adsorbent is arranged below the waste gas exhaust fan.

8. The semi-automatic tablet maker of claim 1, wherein, The semi-automatic tablet machine further comprises a UV disinfection module composed of multiple UV lamps, which is used for disinfecting the operation space area in the equipment cabin, the UV lamps are installed below the top of the equipment cabin, and the switches of the UV lamps are controlled by signal connection with the control system.